KAWASAKI Hiroshi 河崎寛

… Alternative Names

川崎寛カワサキヒロシ

河さき寛カワサキヒロシ

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Researcher Number	80280957
External Links
Affiliation (based on the past Project Information) *help	2009: 東京大学, 医科学研究所, 助教 2007: The University of Tokyo, Institute of Medical Science, Assistant Professor 1996 – 2006: 東京大学, 医科学研究所, 助手 1999: 東京大学, 大学院・医科学研究所, 助手
Review Section/Research Field	Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学 / Biological Sciences Except Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator サイトカイン / ケモカイン / signal transduction / cytokine / シグナル伝達 / 受容体 / 自己免疫 / chemokine / 情報伝達 / 樹状細胞 … More / Autoimmunity / 炎症 / dendritic cell / receptor / Immunology / PCR / 免疫学 / Signal Transduction / Interanl Medicine / アレルギー / 免疫 / 内科学 / Tumor Immunity / Innate Immunity / Acquired Immunity / Receptor / Cytokine / 癌免疫 / 自然免疫 / 獲得免疫 / autoimmunity / infalmmation / allergy / antigen presentation / 自己免疫疾患 / 抗原提示 / チロシンリン酸化 / genetic engineering / hybridoma / 遺伝子工学 / ハイブリドーマ / monoclonal antibody / molecular biology / 箪クローン抗体 / レセプター / 単クローン抗体 / 分子生物学 / 腫瘍免疫 / 免疫療法 … More Except Principal Investigator CD26 / DPPIV / チロシンリン酸化 / CD4メモリーT細胞 / RANTES / Caveolin-1 / CD86 / CD28 / HIV感染 / Tetanus Toxid / CD45RA / ERK / lck / Fyn / Cas-L / T細胞共刺激 / CD4 memory T cells / CD40 / CD27 / SDF-1α / Dipeptidyl peptidase IV / Adenosine deaminase / DPPIV酵素 / 自己免疫疾患 / 共刺激分子 / interference RNA / cord T cell / GVHD / T細胞シグナル / リピッドラフト / アデノシンデアミナーゼ / dipepetidyl peptidase IV / リガンド / 可溶性CD26 / 干渉RNA / 臍帯血T細胞 / autoioimmune diseases / p2l^<ciple> / costimulatory molecule / 共刺激シグナル / 細胞遊走 / IL-2 / CD45 / ラフト分面 / p21^<cipl> / p21^<cip1> / tyrosine phosphorylation / tax transgenic mice / Rheumatoid Arthritis / signal molecule / β1 integrin / β2GPI / 自己抗原 / アポトーシス / 共刺激 / CD9 / CD45ROメモリー / CD45RAナイーブ / T細胞 / taxトランスジェニックマウス / 関節リウマチ / シグナル分子 / β1インテグリン / BM stromal cells / cyclin-dependent kinase / p27(Kip1) / Extracelluar signal-regulated kinase / integrin α5β1 / B cell progenitors cells / T細胞遊走 / Cas-L分子 / インテグリン / VLA / CD29 / p27^<ldpl> / ストローマル細胞 / p27^<kipl> / Extracellular signal-regulated Kinase(ERK) / β1 / インテグリンα1 / 前駆B細胞 / insulin-like growth factor II receptor / mannose 6-phosphate / T cell costimulation / adenosine deaminase / dipeptidyl peptidase IV / リンパ球遊走 / MIP-1β / インスリン成長因子II受容体 / マンノース6リン酸 / ADA / T cell migration / DPPIV enzyme / CD4 naive T cells / CD70 / TNF受容体族 / リンパ球遊送 / CD4ナイーブT細胞 / リンパ球遊素 / DPPIV 酵素 / CD4 メモリーT細胞 / CD4 ナイーブT細胞 / adenosine / Costimulatory molecule / TCR複合体 / CD3 / co-stimulatory分子 / ADA結合蛋白 / costimylatory分子 / アデノシン / Costimulatory / Dipeptidyl peptidaseIV / IRAK-1 / Tollip / CARMA-1 / 共刺激リガンド / メモリーT細胞 / エフェクターT細胞 / TIA-1陽性T細胞 / CD26陽性T細胞 / 異種GVHDマウス / ヒト化CD26抗体 / caveolin.1 / Xeno-GVHD / CD8T細胞 / caveolin-1 / 臨床免疫学 / リウマチ学 / 膠原病 / 抗原提示細胞 / AIDA / AIDS / EBVトランスフォーメーション / リウマトイド因子 / 抗原特異的T細胞 Less

The role of Integrin-downstream signaling molecules in the expression of chemokine receptorsPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
Basic Approach for the Development of Molecular Target Therapy for Autoimmune Diseases and Immune-Mediated Disorders.
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
The isolation and characterization of monoclonal antibodies against human IL-23 receptor.Principal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
Basic study of molecular target therapy for autoimmune diseases and immune deficiency diseases based on CD26
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
IL-12-mediated regulation of human chemokine receptor functionPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
ヒトCD8陽性樹状細胞およびCD8陰性樹状細胞の免疫学的解析と癌免疫療法への応用Principal Investigator
- Principal Investigator
  
  河崎寛
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis of the function of lymphocyte adhesion molecules and its clinical significances in autoimmune diseases
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
The development of specific immune regulatory drugs utilizing the structure and function of CD26
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
The ummunobiology of IL 12 receptors expressed on human dendritic cellsPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Analysis of CD29/VLA integrin in T cell immune regulation and its clinical significance
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Development of specific imuune regulatoly drugs by the cell surface molecules.
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Physiology and pathophysiology of human Interleukin 12 receptor systemPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Determination of molecular basis of immunoregulation of human T cell circuit and its clinical significances
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
HIV感染者におけるウイルス抗原特異的T細胞の誘導
- Principal Investigator
  
  HOSONO Osamu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Development of immunoregulatory therapy via CD26 activation pathway.
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Structural and Functional Analysis of Human Interleukin-12 ReceptorPrincipal Investigator
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo

All 2010 2009 2007 2006 2005 2004

All Journal Article Book

[Book] 内科最新の治療戦略2006
- Author(s)
  河崎寛分担執筆
- Total Pages
  2
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-16590977
[Book] 内科最新の治療専門家からのアドバイス2006
- Author(s)
  河崎寛(分担執筆)
- Total Pages
  456
- Publisher
  南江堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591103
[Book] 腎炎2004
- Author(s)
  河崎寛, 分担執筆
- Total Pages
  173
- Publisher
  文光堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590977
[Journal Article] Microscopic polyangiitis initiated with liver dysfunction, calf pain and fever of unknown origin.2010
- Author(s)
  Ohnuma K, Hosono O, Katayose T, Yoshikawa N, Kawasaki H, Fujii T, Oyaizu N, Tanaka H, Morimoto C
- Journal Title
  
  Rheumatol Int. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] SHP-2 inhibits tyrosine phosphorylation of Cas-L and regulates cell migration2009
- Author(s)
  Yo K, Iwata S, Hashizume Y, Kondo S, Nomura S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 210-4
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] An adult case of Henoch-Schonlein purpura complicating common peroneal nerve mononeuropathy2009
- Author(s)
  Ohnuma K, Hosono O, Kawasaki H, Yoshikawa N, Katayose T, Oyaizu N, Tanaka H, Morimoto C.
- Journal Title
  
  Mod Rheumatol. 19
  
  Pages: 73-9
- NAID
  10025112125
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Microscopic polyangiitis initiated with liver dysfunction, calf pain and fever of unknown origin2009
- Author(s)
  Ohnuma K, Hosono O, Katayose T, Yoshikawa N, Kawasaki H, Fujii T, Oyaizu N, Tanaka H, Morimoto C.
- Journal Title
  
  Rheumatol Int.
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] An adult case of Henoch-Schonlein purpura complicating common peroneal nerve mononeuropathy.2009
- Author(s)
  Ohnuma K, Hosono O, Kawasaki H, Yoshikawa N, Katayose T, Oyaizu N, Tanaka H, Morimoto C
- Journal Title
  
  Mod Rheumatol. 19
  
  Pages: 73-79
- NAID
  10025112125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells.2009
- Author(s)
  Yo K, Iwata S, Hashizume Y, Kondo S, Nomura S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 210-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad72007
- Author(s)
  Inamoto S, Iwata S, Inamoto T, Nomura S, Sasaki T, Urasaki Y, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Oncogene 26
  
  Pages: 893-904
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Current Therapy of Internal Medicine2006
- Author(s)
  Kawasaki H., et. al.
- Journal Title
  
  Medicine, Nankodo, Tokyo, Japan
  
  Pages: 456-456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591103
[Journal Article] HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L)2005
- Author(s)
  Iwata S, Souta-Kuribara A, Yamakawa A, Sasaki T, Shimizu T, Hosono O, Kawasaki H, Tanaka H, Dang NH, Watanabe T, Arima N, Morimoto C.
- Journal Title
  
  Oncogene 24
  
  Pages: 1262-71
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells2005
- Author(s)
  Ohnuma K, Yamochi T, Uchiyama M, Nishibashi K, Iwata S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7743-57
- Data Source
  KAKENHI-PROJECT-17109011

1. HOSONO Osamu (50190210)

# of Collaborated Projects: 10 results

# of Collaborated Products: 9 results
2. MORIMOTO Chikao (30119028)

# of Collaborated Projects: 10 results

# of Collaborated Products: 9 results
3. TANAKA Hirotoshi (00171794)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. IWATA Satoshi (00396871)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. HOMMA Toshio (10282526)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NOJIMA Yoshihisa (90201699)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. WATANABE Sumiko (60240735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TANAKA Toshiaki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YAMOCHI Tadanori (80306844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. OHNUMA Kei (10396872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. IKEDA Teturo (10360489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐藤克明 (40301147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 別宮好文 (70199454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWASAKI Hiroshi 河崎 寛

川崎 寛 カワサキ ヒロシ

河さき 寛 カワサキ ヒロシ

Research Projects

Research Products

Co-Researchers

The role of Integrin-downstream signaling molecules in the expression of chemokine receptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The isolation and characterization of monoclonal antibodies against human IL-23 receptor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IL-12-mediated regulation of human chemokine receptor functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトCD8陽性樹状細胞およびCD8陰性樹状細胞の免疫学的解析と癌免疫療法への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The ummunobiology of IL 12 receptors expressed on human dendritic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiology and pathophysiology of human Interleukin 12 receptor systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

KAWASAKI Hiroshi 河崎寛

川崎寛カワサキヒロシ

河さき寛カワサキヒロシ

[Book] 内科最新の治療戦略2006

[Book] 内科最新の治療専門家からのアドバイス2006