HISAMOTO Naoki 久本直毅

… Alternative Names

久本直毅ヒサモトナオキ

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Researcher Number	80283456
Other IDs
Affiliation (Current)	2025: 名古屋大学, 理学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2025: 名古屋大学, 理学研究科, 教授 2015 – 2016: 名古屋大学, 理学研究科, 准教授 2015: 名古屋大学, 大学院理学研究科, 准教授 2011 – 2015: 名古屋大学, 理学(系)研究科(研究院), 准教授 2009 – 2011: 名古屋大学, 大学院・理学研究科, 准教授 … More 2008 – 2010: Nagoya University, 理学研究科, 准教授 2007: Nagoya University, Biological Science, Associate professor 2006: 名古屋大学, 大学院理学研究科, 助教授 2004 – 2006: 名古屋大学, 大学院・理学研究科, 助教授 2000 – 2003: 名古屋大学, 大学院・理学研究科, 助手 2001: Nagoya University, Graduate School of Science, Division of Biological Science, Research Associate, 院理, 助手 1997 – 1998: 名古屋大学, 大学院・理学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Cell biology / Molecular biology / General medical chemistry / Biological Sciences / Basic Section 44020:Developmental biology-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / General medical chemistry / Basic Section 46010:Neuroscience-general-related / Neurophysiology / General neuroscience / Medical genome science … More Except Principal Investigator … More Functional biochemistry / Cell biology / Cell biology Less
Keywords	Principal Investigator C. elegans / MAPキナーゼ / C.elegans / 神経軸索再生 / C.エレガンス / シグナル伝達 / 神経科学 / 軸索再生 / JNK / C. エレガンス … More / p38 / 神経再生 / ダイイングコード / パーキンソン病 / LRRK2 / 細胞内シグナル伝達 / 線虫 / C.eelgans / RNAi / 神経 / ストレス / シナプス / 血液脳関門 / 透明魚 / モデル生物 / オートファジー / svh / neuron / kinase / Polarized transport / Celegans / キナーゼ / 極性輸送 / ストレス応答 / アルツハイマー病 / APP / アナンダミド / Cエレガンス / LRK-1 / ストレスセンサー / 活性酸素 / 酸化ストレス / P38 … More Except Principal Investigator cDNA / シグナル伝達 / 再生医学 / 軸索再生 / 脳・神経 / 神経科学 / 遺伝学 / gene knockout / cell-specific expression / phospholipase D superfamily / pld-1 gene / phospholipase D / Caenorhabditis elegans / SL-1 / GFP / 遺伝子破壊 / 体内局在 / ホスホリパーゼD類縁遺伝子 / 遺伝子 / ホスホリパーゼD / 線虫 / MVB sorting / EGF受容体 / MVB sortin / ESCRT-0 / ダイニンモータ / エンドサイトーシス / EGF受容 / endocytosis / endosome / EGFR / LRRK1 / モーター蛋白質 / プロテインキナーゼ / 細胞内トラフィック Less

神経軸索再生を制御するシグナルネットワークの解明Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Nagoya University
透明魚を用いた血液脳関門の維持・破綻メカニズムの解明Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Nagoya University
神経軸索再生におけるオートファジー制御因子の役割Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
線虫をモデルとした神経軸索再生制御機構Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Nagoya University
切断軸索からのダイイングコードPrincipal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Analysis of svh genes regulating axon regenerationPrincipal Investigator
- Principal Investigator
  
  Hisamoto Naoki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Nagoya University
残存軸索断片が発信する神経軸索再生制御シグナルPrincipal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
遠位切断軸索からのダイイングコードPrincipal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Regulation of axon regeneration in C. elegansPrincipal Investigator
- Principal Investigator
  
  Hisamoto Naoki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Global identification of factors acting with Parkinson disease/Alzheimer disease genes.Principal Investigator
- Principal Investigator
  
  Hisamoto Naoki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical genome science
- Research Institution
  Nagoya University
アナンダミドによる軸索再生抑制機構の解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Mechanism of signal transduction regulating axon regeneration
- Principal Investigator
  
  MATSUMOTO Kunihiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
酸化ストレスセンサーによるＭＡＰＫカスケード活性化機構の解明Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Analyses of factors acting with Parkinson's disease gene LRRK2 using nematode as a model organismPrincipal Investigator
- Principal Investigator
  
  HISAMOTO Naoki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
MAPキナーゼカスケードを活性化する酸化ストレスセンサーの網羅的同定Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Spatio-temporal regulation of cellular trafficking and signal transduction
- Principal Investigator
  
  MATSUMOTO Kunihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
Genome-wide analysis of C.elegans JNK cascadePrincipal Investigator
- Principal Investigator
  
  HISAMOTO Naoki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
Analysis of LRK-1 kinase which regulates polarized sorting in neuronsPrincipal Investigator
- Principal Investigator
  
  HISAMOTO Naoki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
神経細胞の極性輸送を制御するキナーゼLRK-1の解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
線虫C.elegansをモデル動物としたp38MAPKカスケードの解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Nagoya University
Analysis of stress-activated signal transduction pathway by using nematode as a model animal.Principal Investigator
- Principal Investigator
  
  HISAMOTO Naoki
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
線虫C・elegansをモデル動物としたシナプス局在制御機礎の解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
線虫C.elegansをモデル動物としたp38MAPKカスケードの解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Nagoya University
Functional analysis of phospholipase D (PLD) superfamily in Caenorhabditis elegans
- Principal Investigator
  
  NAKASHIMA Shigeru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Gifu University
線虫C.elegansの神経回路形成に関与するMAPキナーゼ経路の解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
線虫C.elegansの神経特異的な新規MAPキナーゼカスケードの解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
線虫C.elegansの神経特異的な新規MAPキナーゼカスケードの解析Principal Investigator
- Principal Investigator
  
  久本直毅
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Nagoya University

[Journal Article] LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport2022
- Author(s)
  Hanafusa Hiroshi、Kedashiro Shin、Gotoh Mako、Saitoh Ko-hei、Inaba Hironori、Nishioka Tomoki、Kaibuchi Kozo、Inagaki Masaki、Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  Journal of Cell Science
  
  Volume: 135 Issue: 21
- DOI
  10.1242/jcs.259999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06219, KAKENHI-PROJECT-19H00979, KAKENHI-PUBLICLY-22H04643, KAKENHI-PROJECT-21H02578
[Journal Article] Histidine dephosphorylation of the Gβ protein GPB‐1 promotes axon regeneration in C. elegans2022
- Author(s)
  Sakai Yoshiki、Hanafusa Hiroshi、Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  EMBO reports
  
  Volume: 23 Issue: 12
- DOI
  10.15252/embr.202255076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21J15589, KAKENHI-PROJECT-19H00979, KAKENHI-PUBLICLY-22H04643, KAKENHI-PROJECT-21H02578
[Journal Article] The ULK complex?LRRK1 axis regulates Parkin-mediated mitophagy via Rab7 Ser-72 phosphorylation2022
- Author(s)
  Fujita Keitaro、Kedashiro Shin、Yagi Takuya、Hisamoto Naoki、Matsumoto Kunihiro、Hanafusa Hiroshi
- Journal Title
  
  Journal of Cell Science
  
  Volume: 135 Issue: 23
- DOI
  10.1242/jcs.260395
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H00979, KAKENHI-PUBLICLY-22H04643, KAKENHI-PROJECT-21H02578
[Journal Article] Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor2021
- Author(s)
  Shimizu Tatsuhiro、Pastuhov Strahil I.、Hanafusa Hiroshi、Sakai Yoshiki、Todoroki Yasuko、Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 41 Issue: 11 Pages: 2373-2381
- DOI
  10.1523/jneurosci.1024-20.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16911, KAKENHI-PUBLICLY-19H04958, KAKENHI-PROJECT-19H00979, KAKENHI-PROJECT-18H02612, KAKENHI-PROJECT-21H02578
[Journal Article] UNC-16 alters DLK-1 localization and negatively regulates actin and microtubule dynamics in Caenorhabditis elegans regenerating neurons2021
- Author(s)
  Kulkarni Sucheta S、Sabharwal Vidur、Sheoran Seema、Basu Atrayee、Matsumoto Kunihiro、Hisamoto Naoki、Ghosh-Roy Anindya、Koushika Sandhya P
- Journal Title
  
  Genetics
  
  Volume: 219 Issue: 3
- DOI
  10.1093/genetics/iyab139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02578
[Journal Article] CDK14 Promotes Axon Regeneration by Regulating the Noncanonical Wnt Signaling Pathway in a Kinase-Independent Manner2021
- Author(s)
  Hisamoto N, Sakai Y, Ohta K, Shimizu T, Li C, Hanafusa H, Matsumoto K.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 41 Issue: 40 Pages: 8309-8320
- DOI
  10.1523/jneurosci.0711-21.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04958, KAKENHI-PROJECT-18H02612, KAKENHI-PROJECT-21H02578
[Journal Article] BRCA1?BARD1 Regulates Axon Regeneration in Concert with the Gqα?DAG Signaling Network2021
- Author(s)
  Sakai Yoshiki、Hanafusa Hiroshi、Shimizu Tatsuhiro、Pastuhov Strahil I.、Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 41 Issue: 13 Pages: 2842-2853
- DOI
  10.1523/jneurosci.1806-20.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16911, KAKENHI-PUBLICLY-19H04958, KAKENHI-PROJECT-19H00979, KAKENHI-PROJECT-18H02612, KAKENHI-PROJECT-21H02578
[Journal Article] The integrin signaling network promotes axon regeneration via the Src?ephexin?RhoA GTPase signaling axis2021
- Author(s)
  Sakai Yoshiki、Tsunekawa Mayuka、Ohta Kohei、Shimizu Tatsuhiro、Pastuhov Strahil Iv.、Hanafusa Hiroshi、Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 41 Issue: 22 Pages: 4754-4767
- DOI
  10.1523/jneurosci.2456-20.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16911, KAKENHI-PUBLICLY-19H04958, KAKENHI-PROJECT-18H02612, KAKENHI-PROJECT-21H02578
[Journal Article] LRRK1 phosphorylation of Rab7 at S72 links trafficking of EGFR-containing endosomes to its effector RILP2019
- Author(s)
  Hanafusa Hiroshi、Yagi Takuya、Ikeda Haruka、Hisamoto Naoki、Nishioka Tomoki、Kaibuchi Kozo、Shirakabe Kyoko、Matsumoto Kunihiro
- Journal Title
  
  Journal of Cell Science
  
  Volume: 132 Issue: 11
- DOI
  10.1242/jcs.228809
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06911, KAKENHI-PUBLICLY-19H04958, KAKENHI-PUBLICLY-17H06001, KAKENHI-PROJECT-19H00979, KAKENHI-PROJECT-17H03544, KAKENHI-PROJECT-18H02612
[Journal Article] C. elegans Tensin Promotes Axon Regeneration by Linking the Met-like SVH-2 and Integrin Signaling Pathways2019
- Author(s)
  Hisamoto Naoki、Shimizu Tatsuhiro、Asai Kazuma、Sakai Yoshiki、Pastuhov Strahil I.、Hanafusa Hiroshi、Matsumoto Kunihiro
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 39 Issue: 29 Pages: 5662-5672
- DOI
  10.1523/jneurosci.2059-18.2019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16911, KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-19H00979, KAKENHI-PROJECT-17H03544, KAKENHI-PROJECT-18H02612
[Journal Article] N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans2019
- Author(s)
  Shimizu Tatsuhiro、Kato Yuka、Sakai Yoshiki、Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  Genetics
  
  Volume: 213 Issue: 2 Pages: 491-500
- DOI
  10.1534/genetics.119.302492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J14097, KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-19H00979, KAKENHI-PROJECT-17H03544
[Journal Article] TDP2 Negatively Regulates Axon Regeneration by Inducing SUMOylation of an Ets Transcription Factor2019
- Author(s)
  Sakai Yoshiki、Hanafusa Hiroshi、Pastuhov Strahil Iv、Shimizu Tatsuhiro、Li Chun、Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  EMBO reports
  
  Volume: 20 Issue: 10
- DOI
  10.15252/embr.201847517
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16911, KAKENHI-PUBLICLY-19H04958, KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-19H00979, KAKENHI-PROJECT-17H03544, KAKENHI-PROJECT-18H02612
[Journal Article] The C. elegans BRCA2‐ALP/Enigma complex regulates axon regeneration via a Rho GTPase- ROCK-MLC phosphorylation pathway2018
- Author(s)
  Shimizu, T., Pastuhov, S., Matsumoto, K., Hisamoto, N.
- Journal Title
  
  Cell Rep.
  
  Volume: 24 Issue: 7 Pages: 1880-1889
- DOI
  10.1016/j.celrep.2018.07.049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02388, KAKENHI-PUBLICLY-17H05501, KAKENHI-PROJECT-17H03544
[Journal Article] Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration.2018
- Author(s)
  Hisamoto, N., Tsuge, A., Pastuhov, S., Shimizu, T., Hanafusa, H., Matsumoto, K.
- Journal Title
  
  Nature Commun.
  
  Volume: 9 Issue: 1 Pages: 3099-3099
- DOI
  10.1038/s41467-018-05478-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02388, KAKENHI-PUBLICLY-17H05501, KAKENHI-PROJECT-17H03544, KAKENHI-PROJECT-18H02612
[Journal Article] Heavy Metal Stress Assay of Caenorhabditis elegans2017
- Author(s)
  Pastuhov Strahil、Shimizu Tatsuhiro、Hisamoto Naoki
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 7 Issue: 11 Pages: 2312-2312
- DOI
  10.21769/bioprotoc.2312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16F16113, KAKENHI-PUBLICLY-17H05501, KAKENHI-PROJECT-17H03544
[Journal Article] Signal transduction cascades in axon regeneration: insights from C. elegans2017
- Author(s)
  Hisamoto Naoki、Matsumoto Kunihiro
- Journal Title
  
  Curr. Opin. Genet. Dev.
  
  Volume: 44 Pages: 54-60
- DOI
  10.1016/j.gde.2017.01.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02388, KAKENHI-PUBLICLY-17H05501, KAKENHI-PROJECT-17H03544
[Journal Article] UNC-16/JIP3 regulates early events in synaptic vesicle protein trafficking via LRK-1/LRRK2 and AP complexes2017
- Author(s)
  Choudhary Bikash、Kamak Madhushree、Ratnakaran Neena、Kumar Jitendra、Awasthi Anjali、Li Chun、Nguyen Ken、Matsumoto Kunihiro、Hisamoto Naoki、Koushika Sandhya P.
- Journal Title
  
  PLOS Genetics
  
  Volume: 13 Issue: 11 Pages: 1-25
- DOI
  10.1371/journal.pgen.1007100
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19032, KAKENHI-PUBLICLY-17H05501, KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-17H03544
[Journal Article] Endocannabinoid signaling regulates regenerative axon navigation in C. elegans via the GPCRs NPR-19 and NPR-32.2016
- Author(s)
  Pastuhov, S., Matsumoto, K., Hisamoto, N.
- Journal Title
  
  Genes Cells
  
  Volume: 21 Issue: 7 Pages: 696-705
- DOI
  10.1111/gtc.12377
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-16F16113, KAKENHI-PUBLICLY-15H01375, KAKENHI-PROJECT-26293063
[Journal Article] Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans2016
- Author(s)
  Tanimul Alam, Hiroki Maruyama, Chun Li, Strahil Iv. Pastuhov, Paola Nix, Michael Bastiani, Naoki Hisamoto& Kunihiro Matsumoto
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 10388-10388
- DOI
  10.1038/ncomms10388
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J03481, KAKENHI-PROJECT-26640123, KAKENHI-PROJECT-15H02388, KAKENHI-PUBLICLY-15H01375, KAKENHI-PROJECT-26293063
[Journal Article] Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi2016
- Author(s)
  Fukuzono T, Pastuhov SI, Fukushima O1, Li C, Hattori A, Iemura SI, Natsume T, Shibuya H, Hanafusa H, Matsumoto K, Hisamoto N.
- Journal Title
  
  Genes　Cells．
  
  Volume: 21(4) Issue: 4 Pages: 311-24
- DOI
  10.1111/gtc.12338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-26640123, KAKENHI-PUBLICLY-15H01375, KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-26293063, KAKENHI-PROJECT-16K19032
[Journal Article] The C. elegans discoidin domain receptor DDR-2 modulates the Met-like RTK-JNK signaling pathway in axon regeneration.2016
- Author(s)
  Hisamoto, N., Nagamori, Y., Shimizu, T., Pastuhov, S., Matsumoto, K.
- Journal Title
  
  PLoS Genet.
  
  Volume: 12 Issue: 12 Pages: e1006475-e1006475
- DOI
  10.1371/journal.pgen.1006475
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02388, KAKENHI-PUBLICLY-15H01375, KAKENHI-PROJECT-26293063
[Journal Article] The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Signaling Pathway in Axon Regeneration.2016
- Author(s)
  Pastuhov SI, Fujiki K, Tsuge A, Asai K, Ishikawa S, Hirose K, Matsumoto K, Hisamoto N.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 36 Pages: 9710-9721
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Journal Article] The core molecular machinery used for engulfment of apoptotic cells regulates the JNK pathway mediating axon regeneration in Caenorhabditis elegans.2016
- Author(s)
  Pastuhov SI, Fujiki K, Tsuge A, Asai K, Ishikawa S, Hirose K, Matsumoto K, Hisamoto N.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 12 Issue: 37 Pages: 9710-9721
- DOI
  10.1523/jneurosci.0453-16.2016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16F16113, KAKENHI-PROJECT-15K18910, KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-26293063
[Journal Article] Axon regeneration is regulated by Ets–C/EBP transcription complexes generated by activation of the cAMP/Ca2+ signaling pathways.2015
- Author(s)
  Li, C., Hisamoto, N., and Matsumoto, K.
- Journal Title
  
  PLoS Genet.
  
  Volume: 11 Issue: 10 Pages: e1005603-e1005603
- DOI
  10.1371/journal.pgen.1005603
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24247025, KAKENHI-PUBLICLY-15H01375, KAKENHI-PROJECT-15H02388, KAKENHI-PROJECT-26293063
[Journal Article] Axon regeneration is regulated by Ets-C/EBP transcription complexes generated by activation of the cAMP/Ca2+–p38 MAPK signaling pathways.2015
- Author(s)
  Li C, Hisamoto N, and Matsumoto K
- Journal Title
  
  PLoS Genetics
  
  Volume: 11
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26640123
[Journal Article] MAP kinase cascades regulating axon regeneration in <i>C. elegans</i>2015
- Author(s)
  Pastuhov SI, Hisamoto N., Matsumoto K.
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 91 Issue: 3 Pages: 63-75
- DOI
  10.2183/pjab.91.63
- NAID
  130004802307
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25116713, KAKENHI-PROJECT-26640123, KAKENHI-PUBLICLY-15H01375, KAKENHI-PROJECT-26293063
[Journal Article] The C. elegans HGF/plasminogen-like protein SVH-1 has protease-dependent and -independent functions.2014
- Author(s)
  Hisamoto, N., Li, C., Yoshida, M., Matsumoto, K.
- Journal Title
  
  Cell Reports
  
  Volume: 9 Issue: 5 Pages: 1628-1634
- DOI
  10.1016/j.celrep.2014.10.056
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03077, KAKENHI-PUBLICLY-25116713, KAKENHI-PROJECT-26293063, KAKENHI-PROJECT-26640123
[Journal Article] 軸索再生とMAPキナーゼ2013
- Author(s)
  久本直毅、松本邦弘
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 667-668
- Data Source
  KAKENHI-PROJECT-23590331
[Journal Article] The C. elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complex2013
- Author(s)
  Ayuna Hattori
- Journal Title
  
  PLOS Genetics
  
  Volume: 9 Issue: 2 Pages: e1003315-e1003315
- DOI
  10.1371/journal.pgen.1003315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J03280, KAKENHI-PROJECT-23590331, KAKENHI-PROJECT-23770217, KAKENHI-PUBLICLY-25116713, KAKENHI-PUBLICLY-23117708
[Journal Article] 軸索再生とMAPキナーゼ2013
- Author(s)
  久本直毅、松本邦弘
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 31 Pages: 667-668
- Data Source
  KAKENHI-PUBLICLY-25116713
[Journal Article] Forgetting in C. elegans is accelerated by neuronal communication via the TIR-1/JNK-1 pathway.2013
- Author(s)
  Inoue A, Sawatari E, Hisamoto N, Kitazono T, Teramoto T, Fujiwara M, Matsumoto K, Ishihara T.
- Journal Title
  
  Cell Reports
  
  Volume: 3(3) Issue: 3 Pages: 808-819
- DOI
  10.1016/j.celrep.2013.02.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23370002, KAKENHI-PROJECT-23570007, KAKENHI-PROJECT-23590331, KAKENHI-PROJECT-24247025, KAKENHI-PROJECT-24650167, KAKENHI-PUBLICLY-25116713, KAKENHI-PLANNED-20115003, KAKENHI-PUBLICLY-23117708
[Journal Article] The growth factor SVH-1 regulates axon regeneration in C.elegans via the JNK MAPK cascade2012
- Author(s)
  Chun Li
- Journal Title
  
  Nature Neuroscience
  
  Volume: 15 Issue: 4 Pages: 551-557
- DOI
  10.1038/nn.3052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09457, KAKENHI-PROJECT-21247031, KAKENHI-PUBLICLY-23117708, KAKENHI-PROJECT-23590331, KAKENHI-PROJECT-23770217, KAKENHI-PROJECT-24247025
[Journal Article] Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling.2012
- Author(s)
  Pastuhov et al.
- Journal Title
  
  Nature Communications
  
  Volume: 3 Issue: 1 Pages: 1136-1136
- DOI
  10.1038/ncomms2136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590331, KAKENHI-PROJECT-24657001, KAKENHI-PUBLICLY-23117708
[Journal Article] Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins2011
- Author(s)
  Hayakawa, T., Kato, K., Hayakawa, R., Hisamoto, N., Matsumoto, K., Takeda, K. and Ichijo, H.
- Journal Title
  
  Genetics
  
  Volume: 187 Issue: 3 Pages: 785-792
- DOI
  10.1534/genetics.110.124883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-21247031, KAKENHI-PUBLICLY-23117510, KAKENHI-PROJECT-23590331
[Journal Article] Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegans2011
- Author(s)
  Yuan, Y., Cao, P., Smith, M. A., Kramp, K., Huang, Y., Hisamoto, N., Matsumoto, K., Hatzoglou, M., Jin, H., and Feng, Z
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 8 Pages: e22354-e22354
- DOI
  10.1371/journal.pone.0022354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031, KAKENHI-PUBLICLY-22020016, KAKENHI-PUBLICLY-23117708, KAKENHI-PROJECT-23590331
[Journal Article] elegans JIP3 protein UNC-16 functions as an adaptor to link kinesin-1 with cytoplasmic dynein.2011
- Author(s)
  Arimoto M, Koushika SP, Choudhary B, Li C, Matsumoto K, Hisamoto N The C.
- Journal Title
  
  J.Neurosci. 31
  
  Pages: 2216-2224
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways2011
- Author(s)
  Nix, P., Hisamoto, H., Matsumoto, K., and Bastiani, M
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 108 Issue: 26 Pages: 10738-10743
- DOI
  10.1073/pnas.1104830108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031, KAKENHI-PUBLICLY-23117708, KAKENHI-PROJECT-23590331
[Journal Article] The C. elegans JIP3 protein UNC-16 functions as an adaptor to link kinesin-1 with cytoplasmic dynein2011
- Author(s)
  Arimoto, M., Koushika, S. P., Choudhary, B. C., Li, C., Matsumoto, K., and Hisamoto, N
- Journal Title
  
  J. Neurosci
  
  Volume: 31 Issue: 6 Pages: 2216-2224
- DOI
  10.1523/jneurosci.2653-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031, KAKENHI-PROJECT-23590331
[Journal Article] Regulation of Anoxic Death in Caenorhabditis elegans by Mammalian Apoptosis Signal-Regulating Kinase (ASK) Family Proteins.2011
- Author(s)
  Hayakawa T, Kato K, Hayakawa R, Hisamoto N, Matsumoto K, Takeda K, Ichijo H.
- Journal Title
  
  Genetics. 187
  
  Pages: 785-792
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans.2010
- Author(s)
  Okuyama T, Inoue H, Ookuma S, Satoh T,Kano K, Honjoh S, Hisamoto N, Matsumoto K, Nishida E.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 30274-30281
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans2010
- Author(s)
  Okuyama, T., Inoue, H., Ookuma, S., Satoh, T., Kano, K., Honjoh, S., Hisamoto, N., Matsumoto, K. and Nishida, E.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Issue: 39 Pages: 30274-30281
- DOI
  10.1074/jbc.m110.146274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227004, KAKENHI-PROJECT-21247031
[Journal Article] Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans2010
- Author(s)
  Shivers, R. P., Pagano, D. J., Kooistra1, T., Richardson, C. E., Reddy, K. C., Whitney, J. K., Matsumoto, K., Hisamoto, N., and Kim, D. H
- Journal Title
  
  PLoS Genet
  
  Volume: 6 Issue: 4 Pages: e1000892-e1000892
- DOI
  10.1371/journal.pgen.1000892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031
[Journal Article] Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans.2010
- Author(s)
  Shivers RP, Pagano DJ, Kooistra T, Richardson CE, Reddy KC, Whitney JK, Kamanzi O, Matsumoto K, Hisamoto N, Kim DH.
- Journal Title
  
  PLoS Genet. 6
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the c-Jun N-terminal kinase signaling pathway mediating the stress response.2010
- Author(s)
  Fujiki K, Mizuno T, Hisamoto N, Matsumoto K.
- Journal Title
  
  Mol.Cell.Biol. 30
  
  Pages: 995-1003
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] Phosphorylation of the Conserved Transcription Factor ATF-7 by PMK-1 p38 MAPK Regulates Innate Immunity in Caenorhabditis elegans.2010
- Author(s)
  Shivers, R.P., Pagano, D.J., Kooistra, T., Richardson, C.E., Reddy, K.C., Whitney, J.K., Matsumoto, K., Hisamoto, N., Kim, D.H.
- Journal Title
  
  PloS Genet.
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031
[Journal Article] The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the JNK signaling pathway mediating the stress response2010
- Author(s)
  Fujiki, K., Mizuno, T., Hisamoto, N., and Matsumoto, K
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 30 Issue: 4 Pages: 995-1003
- DOI
  10.1128/mcb.01131-09
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031
[Journal Article] C. elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation2009
- Author(s)
  Hiatt, S.M., Duren, H.M., Shyu, Y.J., Ellis, R.E., Hisamoto, N., Matsumoto, K., Kariya, K., Kerppola, T.M., Hu, C-D.
- Journal Title
  
  Mol.Biol.Cell 20
  
  Pages: 3888-3895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031
[Journal Article] LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans.2009
- Author(s)
  Saha S, Guillily MD, Ferree A, Lanceta J, Chan D, Ghosh J, Hsu CH, Segal L, Raghavan K, Matsumoto K, Hisamoto N, Kuwahara T, Iwatsubo T, Moore L, Goldstein L, Cookson M, Wolozin B.
- Journal Title
  
  J.Neurosci. 29
  
  Pages: 9210-9218
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] The Germinal Center Kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C. elegans germline2009
- Author(s)
  Schouest, K. R., Kurasawa, Y., Furuta, T., Hisamoto, N., Matsumoto, K., and Schumacher, J. M
- Journal Title
  
  PLoS One
  
  Volume: 4 Issue: 10 Pages: e7450-e7450
- DOI
  10.1371/journal.pone.0007450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031
[Journal Article] C. elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation2009
- Author(s)
  Hiatt, S. M., Duren, H. M., Shyu, Y. J., Ellis, R. E., Hisamoto, N., Matsumoto, K., Kariya, K., Kerppola, T. M., and Hu, C-D
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 20 Issue: 17 Pages: 3888-3895
- DOI
  10.1091/mbc.e08-08-0833
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031
[Journal Article] The germinal center kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C.elegans germline.2009
- Author(s)
  Schouest KR, Kurasawa Y, Furuta T, Hisamoto N, Matsumoto K, Schumacher JM.
- Journal Title
  
  PLoS One 4
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] LRRK2 modulates vulnerability to mitochondrial dysfunction in C. elegans2009
- Author(s)
  Saha, S., Guillily, M., Ferree, A., Lanceta, J., Chan, D., Ghosh, J., Hsu, C., Segal, L., Raghavan, K., Matsumoto, K., Hisamoto, N., Kuwahara, T., Iwatsubo, T., Moore, L., Goldstein, L., Cookson, M., and Wolozin, B
- Journal Title
  
  J. Neurosci
  
  Volume: 29 Issue: 29 Pages: 9210-9218
- DOI
  10.1523/jneurosci.2281-09.2009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247031
[Journal Article] Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation.2009
- Author(s)
  Hiatt SM, Duren HM, Shyu YJ, Ellis RE, Hisamoto N, Matsumoto K, Kariya K, Kerppola TK, Hu CD.
- Journal Title
  
  Mol.Biol.Cell. 20
  
  Pages: 3888-3895
- Data Source
  KAKENHI-PROJECT-20570181
[Journal Article] C. elegans WNK-STE20 pathway regulates tube formation by modulating C1C channel activity.2008
- Author(s)
  Hisamoto N, et. al.
- Journal Title
  
  EMBO reports 9
  
  Pages: 70-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570174
[Journal Article] C. elegans WNK-STE20 pathway regulates tube formation by modulating CIC channel activity2008
- Author(s)
  Hisamoto, N, et. al.
- Journal Title
  
  EMBO reports 9
  
  Pages: 70-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570174
[Journal Article] C. elegans WNK-STE20 pathway regulates tube formation by mod ulating ClC channel activity.2008
- Author(s)
  Hisamoto N, et. al.,
- Journal Title
  
  EMBO reports 9
  
  Pages: 70-75
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570174
[Journal Article] LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins.2007
- Author(s)
  Sakaguchi-Nakashima, A., Meir, J. Y., Jin, Y., ^*Matsumoto, K., Hisamoto, N.
- Journal Title
  
  Curr. Biol. 17
  
  Pages: 592-598
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] Regulation of the Caenorhabditis elegans oxidative stress defence protein SKN-1 by glycogen synthase kinase-3.2005
- Author(s)
  An, J. H., Vranas, K., Lucke, M., Inoue, H., Hisamoto, N., Matsumoto, K., ^*Blackwell, T. K.
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A. 102
  
  Pages: 16275-16280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] The Caenorhabditis elegans UNC-14 RUN domain protein binds to the Kinesin-1/UNC-16 complex and regulates synaptic vesicle localization.2005
- Author(s)
  Sakamoto, R., Byrd, D. T., Hisamoto, N., ^*Matsumoto, K., ^*Jin, Y.
- Journal Title
  
  Mol. Biol. Cell 16
  
  Pages: 483-496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.2005
- Author(s)
  Moriguchi, T., Urushiyama, S., Hisamoto N., Iemura, S., Uchida, S., Natsume, T., Matsumoto, K., ^*Shibuya H.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 42685-42693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response.2005
- Author(s)
  Inoue, H., Hisamoto, N., An, J. H., Oliveira, R. P., Nishida, E., Blackwell, T. K., ^*Matsumoto, K.
- Journal Title
  
  Genes Dev. 19
  
  Pages: 2278-2283
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] The C. elegans UNC-14 RUN domain protein binds to the Kinesin-1/UNC-16 complex and regulates synaptic vesicle localization.2004
- Author(s)
  Sakamoto, R., Byrd, D. T., Hisamoto, N., Matsumoto, K., ^*Jin, Y.
- Journal Title
  
  Mol. Biol. Cell 16
  
  Pages: 483-496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans.2004
- Author(s)
  ^*Nishiwaki, K., Kubota, Y., Chigira, Y., Roy, S. K., Suzuki, M., Schvarzstein, M., Jigami, Y., Hisamoto, N., Matsumoto, K.
- Journal Title
  
  Nat. Cell Biol. 6
  
  Pages: 31-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] Roles of MAP kinase cascades in Caenorhabditis elegans.2004
- Author(s)
  Sakaguchi, A., Matsumoto, K., Hisamoto, N.
- Journal Title
  
  J. Biochem. (Tokyo) 136
  
  Pages: 7-11
- NAID
  10016200538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase.2004
- Author(s)
  Kim, D. H., Liberati, N. T., Mizuno, T., Hisamoto, N., Matsumoto, K., ^*Ausubel, F. M
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 101
  
  Pages: 10990-10994
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response.2004
- Author(s)
  Mizuno, T., Hisamoto, N., Terada, T., Kondo, T., Adachi, M., Nishida, E., Kim, D. H., Ausubel, F. M., ^*Matsumoto, K.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2226-2234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Journal Article] A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.2002
- Author(s)
  Kim, D. H., Feinbaum, R., Alloing, G., Emerson, F. E., Garsin, D. A., Inoue, H., Tanaka-Hino, M., Hisamoto, N., Matsumoto, K., Tan, M. W., ^*Ausubel, F. M.
- Journal Title
  
  Science 297
  
  Pages: 623-626
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14086206
[Presentation] BRCA1-BARD1はGqα-DAGシグナルネットワークと協調して神経軸索再生を制御する2021
- Author(s)
  酒井　芳樹・久本　直毅・松本　邦弘
- Organizer
  第４４回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02578
[Presentation] 線虫におけるケミカルシグナル-GPCR-Gqα経路を介した神経軸索再生の制御機構2021
- Author(s)
  杉浦　佳代子・久本　直毅・松本　邦弘
- Organizer
  第４４回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02578
[Presentation] SWI/SNFクロマチンリモデリング複合体による神経軸索再生制御機構2021
- Author(s)
  出原　魁人・久本　直毅・松本　邦弘
- Organizer
  第４４回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02578
[Presentation] インテグリンシグナルネットワークはSrc-Ephexin-RhoAシグナル軸を介して神経軸索再生を促進する2021
- Author(s)
  恒川　真有香・久本　直毅・松本　邦弘
- Organizer
  第４４回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02578
[Presentation] Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration.2019
- Author(s)
  Pastuhov SI, Hisamoto N, tsuge A, Shimizu T, Hanafusa H, Matsumoto K.
- Organizer
  22st International C. elegans Conference, Los Angeles, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03544
[Presentation] C. elegans Tensin promotes axon regeneration by connecting the Met-like SVH-2 and integrin signaling pathway.2019
- Author(s)
  Shimizu T, Asai K, Sakai Y, Pastuhov SI, Hanafusa H, Matsumoto K, Hisamoto N.
- Organizer
  22st International C. elegans Conference, Los Angeles, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03544
[Presentation] C. elegans TDP2 homolog negatively regulates axon regeneration by inducing SUMOylatiuon of an Ets transcription factor.2019
- Author(s)
  Sakai Y, Hanafusa H, Li C, Shimizu T, Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  22st International C. elegans Conference, Los Angeles, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03544
[Presentation] 線虫EnigmaホモログによるRhoキナーゼシグナルを介した神経軸索再生制御2017
- Author(s)
  清水達太、松本邦弘、久本直毅
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05501
[Presentation] 線虫においてコンドロイチン硫酸は加齢依存的な神経軸索の再生能低下に関与する2017
- Author(s)
  竹生実希子、松本邦弘、久本直毅
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03544
[Presentation] N-glycosylation is required for axon regeneration in Caenorhabditis elegans through modification of discoidin domain receptor.2017
- Author(s)
  Takeo M, Kato Y, Matsumoto K, K, Hisamoto N
- Organizer
  21st International C. elegans Conference, Los Angeles, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05501
[Presentation] The role of serotonin in C. elegans axon regeneration.2017
- Author(s)
  Hisamoto N
- Organizer
  International Workshop on NeuroScience, Nagoya, Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03544
[Presentation] The role of serotonin in C. elegans axon regeneration.2017
- Author(s)
  Hisamoto N
- Organizer
  International Workshop on NeuroScience, Nagoya, Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05501
[Presentation] Discoidin domain receptor DDR-2 modulates the Met-like RTK-JNK signaling pathway in axon regeneration.2017
- Author(s)
  T. Shimizu, Y. Nagamori, K. Matsumoto, N. Hisamoto, S. Pastuhov
- Organizer
  21st International C. elegans Conference、UCLA, 2017.7
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16113
[Presentation] 線虫においてコンドロイチン硫酸は加齢依存的な神経軸索の再生能低下に関与する2017
- Author(s)
  竹生実希子、松本邦弘、久本直毅
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05501
[Presentation] N-glycosylation is required for axon regeneration in Caenorhabditis elegans through modification of discoidin domain receptor.2017
- Author(s)
  Takeo M, Kato Y, Matsumoto K, K, Hisamoto N
- Organizer
  21st International C. elegans Conference, Los Angeles, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03544
[Presentation] 線虫EnigmaホモログによるRhoキナーゼシグナルを介した神経軸索再生制御2017
- Author(s)
  清水達太、松本邦弘、久本直毅
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03544
[Presentation] 細胞死シグナルによる神経軸索再生の制御機構2016
- Author(s)
  柘植杏菜, 久本直毅, 松本邦弘
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] hoシグナル伝達経路はアクチン/ミオシン細胞骨格の再構成を介して線虫の神経軸索再生を制御する2016
- Author(s)
  アラムタニムル, 久本直毅, 松本邦弘
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Axotomy-induced HIF-serotonin signallyng axis promotes axon regeneration in C. elegans.2016
- Author(s)
  Alam T, Maruyama H, Li C, Pastuhov SI, Nix P, Bastiani M, Hisamoto N, Matsumoto K.
- Organizer
  Neuronal development, synaptic function & behavior C. elegans topic meeting 2016. Nagoya, Japan, Jul. 27-30, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Regulation of axon regeneration by axotomy-induced serotonin signaling.2016
- Author(s)
  Strahil SI, Hisamoto N, Matsumoto K.
- Organizer
  The 1st Indian C. elegans meeting
- Place of Presentation
  India, Munbai
- Year and Date
  2016-01-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Axotomy-induced HIF-serotonin signallyng axis promotes axon regeneration in C. elegans.2016
- Author(s)
  Alam T, Maruyama H, Li C, Pastuhov SI, Nix P, Bastiani M, Hisamoto N, Matsumoto K.
- Organizer
  7th Asia-pacific C. elegans meeting, Beijing, China, Jun. 25-29, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Regulation of axon regeneration by axotomy-induced serotonin signaling2016
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  The 1st Indian C. elegans meeting
- Place of Presentation
  Munbai, India
- Year and Date
  2016-01-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Axotomy-induced HIF-serotonin signallyng axis promotes axon regeneration in C. elegans.2016
- Author(s)
  Alam T, Maruyama H, Li C, Pastuhov SI, Nix P, Bastiani M, Hisamoto N, Matsumoto K.
- Organizer
  Neuronal development, synaptic function & behavior C. elegans topic meeting 2016. Nagoya, Japan, Jul. 27-30, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Engulfment machinery regulates axon regeneration via the JNK pathway.2016
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  7th Asia-pacific C. elegans meeting
- Place of Presentation
  Beijing, China
- Year and Date
  2016-06-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16113
[Presentation] 乳癌原因遺伝子BRCA2の線虫ホモログBRC-2はRho-ROCK-MLCリン酸化経路で神経軸索再生を制御する2016
- Author(s)
  清水達太, 久本直毅, 松本邦弘
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Rhoシグナル伝達経路はアクチン/ミオシン細胞骨格の再構成を介して線虫の神経軸索再生を制御する2016
- Author(s)
  アラムタニムル, 久本直毅, 松本邦弘
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Engulfment machinery regulates axon regeneration via the JNK pathway.2016
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  7th Asia-pacific C. elegans meeting, Beijing, China, Jun. 25-29, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Axon regeneration is regulated by Ets-C/EBP transcription complexes generated by activation of the cAMP-Ca2+ signaling pathways.2016
- Author(s)
  Li C, Hisamoto N, Matsumoto K.
- Organizer
  7th Asia-pacific C. elegans meeting, Beijing, China, Jun. 25-29, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Engulfment machinery regulates axon regeneration via the JNK pathway.2016
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  Neuronal development, synaptic function & behavior C. elegans topic meeting 2016. Nagoya, Japan, Jul. 27-30, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Engulfment machinery regulates axon regeneration via the JNK pathway.2016
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  7th Asia-pacific C. elegans meeting, Beijing, China, Jun. 25-29, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] インテグリンー Rac貪食経路はJNK経路を活性化し、線虫の神経軸索再生を促進する2016
- Author(s)
  Strahil Iv. Pastuhov, 松本邦弘, 久本直毅
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] 細胞死シグナルによる神経軸索再生の制御機構2016
- Author(s)
  柘植杏菜, 久本直毅, 松本邦弘
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Axotomy-induced HIF-serotonin signallyng axis promotes axon regeneration in C. elegans.2016
- Author(s)
  Alam T, Maruyama H, Li C, Pastuhov SI, Nix P, Bastiani M, Hisamoto N, Matsumoto K.
- Organizer
  7th Asia-pacific C. elegans meeting, Beijing, China, Jun. 25-29, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] 乳癌原因遺伝子BRCA2の線虫ホモログBRC-2はRho-ROCK-MLCリン酸化経路で神経軸索再生を制御する2016
- Author(s)
  清水達太, 久本直毅, 松本邦弘
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Engulfment machinery regulates axon regeneration via the JNK pathway.2016
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  Neuronal development, synaptic function & behavior C. elegans topic meeting
- Place of Presentation
  Nagoya Japan
- Year and Date
  2016-07-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16113
[Presentation] インテグリンー Rac貪食経路はJNK経路を活性化し、線虫の神経軸索再生を促進する2016
- Author(s)
  Strahil Iv. Pastuhov, 松本邦弘, 久本直毅
- Organizer
  第39回日本分子生物学会年会、2016.11.30　横浜
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Axon regeneration is regulated by Ets-C/EBP transcription complexes generated by activation of the cAMP-Ca2+ signaling pathways.2016
- Author(s)
  Li C, Hisamoto N, Matsumoto K.
- Organizer
  7th Asia-pacific C. elegans meeting, Beijing, China, Jun. 25-29, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Engulfment machinery regulates axon regeneration via the JNK pathway.2016
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  Neuronal development, synaptic function & behavior C. elegans topic meeting 2016. Nagoya, Japan, Jul. 27-30, 2016.
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] UNC-16 regulates early steps of synaptic vesicle protein trafficking via LRK-1 and UNC-101.2015
- Author(s)
  Choudhary B, Kamak M, Kumar M, Awasthi A, Fukuzono T, Li C, Nguyen K, Matsumoto K, Hisamoto N, Koushika S.
- Organizer
  20th International C. elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2015-06-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] トランスサイレチン様因子TTR-11による神経軸索再生の制御機構2015
- Author(s)
  柘植杏菜、久本直毅、松本邦弘
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] トランスサイレチン様因子TTR-11による神経軸索再生の制御機構2015
- Author(s)
  柘植杏菜、久本直毅、松本邦弘
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Identification of endocannabinoid receptors regulating axon regeneration in C. elegans2015
- Author(s)
  パストゥホフストラヒル、久本直毅、松本邦弘
- Organizer
  6th International Conference on Phospholipase A2 and Lipid Mediators (PLM2015)
- Place of Presentation
  Keyo Plaza Hotel, Tokyo
- Year and Date
  2015-02-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] Cyclic AMP and an Ets transcription factor are required for the transcriptional induction of svh-2 by axon severing.2015
- Author(s)
  Li C, Hisamoto N, Matsumoto K.
- Organizer
  20th International C. elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] A tensin3 homolog SVH-6 regulates axon regeneration by stabilization of a MET-like receptor tyrosine kinase SVH-22015
- Author(s)
  Alam T, Asai K, Hisamoto N, Matsumoto K.
- Organizer
  20th International C. elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] UNC-16 regulates early steps of synaptic vesicle protein trafficking via LRK-1 and UNC-101.2015
- Author(s)
  Choudhary B, Kamak M, Kumar M, Awasthi A, Fukuzono T, Li C, Nguyen K, Matsumoto K, Hisamoto N, Koushika S.
- Organizer
  20th International C. elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] 線虫のBRCA2はRhoシグナル-MLCリン酸化経路で神経軸索再生を制御する2015
- Author(s)
  清水達太、久本直毅、松本邦弘
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] A tensin3 homolog SVH-6 regulates axon regeneration by stabilization of a MET-like receptor tyrosine kinase SVH-22015
- Author(s)
  Alam T, Asai K, Hisamoto N, Matsumoto K.
- Organizer
  20th International C. elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01375
[Presentation] Cyclic AMP and an Ets transcription factor are required for the transcriptional induction of svh-2 by axon severing.2015
- Author(s)
  Li C, Hisamoto N, Matsumoto K.
- Organizer
  20th International C. elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] 線虫のBRCA2はRhoシグナル-MLCリン酸化経路で神経軸索再生を制御する2015
- Author(s)
  清水達太、久本直毅、松本邦弘
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] 線虫の神経軸再生を制御するエンドカンナビノイド受容体の同定2014
- Author(s)
  パストゥホフストラヒル、久本直毅、松本邦弘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] セロトニン伝達経路による神経軸索再生の制御機構2014
- Author(s)
  丸山裕生、アラムタニムル、久本直毅、松本邦弘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] SVH-5 transcription factor regulates axon regeneration in C. elegans by activating the transcription of the svh-2 gene encoding a receptor tyrosine kinase2014
- Author(s)
  Chun Li, Naoki Hisamoto, Kunihiro Matsumoto
- Organizer
  C. elegans Development, Cell Biology and Gene Expression Meeting in association with The 6th Asia-Pacific C. elegans Meeting
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2014-07-15
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] 線虫のRhoシグナル伝達経路はミオシン軽鎖のリン酸化を介して神経軸索再生を制御する2014
- Author(s)
  アラムタニムル、丸山裕生、久本直毅、松本邦弘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] セロトニン・Rhoシグナル伝達経路による神経軸索再生の制御機構2014
- Author(s)
  アラムタニムル、久本直毅、松本邦弘
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂東大寺総合文化センター
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] 糖鎖修飾因子群による神経軸索の再生制御2014
- Author(s)
  加藤優佳、久本直毅、松本邦弘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] 線虫HGF/プラスミノーゲン様タンパク質SVH-1は増殖因子としてだけではなく細胞外マトリクスを調節するプロテアーゼとしても機能する2014
- Author(s)
  久本直毅、李春、吉田誠希、松本邦弘
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] The UNC-23–HSP-1 chaperone system determines localization of Parkinson disease-related kinase LRK-1 in C. elegans2014
- Author(s)
  Tanimul Alam, Takashi Fukuzono, Strahil Pastuhov, Okinobu Fukushima, Chun Li, Ayuna Hattori, Hiroshi Hanafusa, Kunihiro Matsumoto, Naoki Hisamoto
- Organizer
  Society for Neuroscience annual meeting 2014
- Place of Presentation
  Walter E. Washington Convention Center
- Year and Date
  2014-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] The C. elegans plasminogen/HGF-like protein SVH-1 is required for larval developmental growth.2013
- Author(s)
  Naoki Hisamoto
- Organizer
  19th International C.elegans meeting
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-23590331
[Presentation] Regulatory mechanism of axonal regeneration in C. elegans2013
- Author(s)
  永盛友樹、久本直毅、松本邦弘
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインクあいち
- Data Source
  KAKENHI-PROJECT-24247025
[Presentation] The C. elegans plasminogen/HGF-like protein SVH-1 is required for larval developmental growth.2013
- Author(s)
  Naoki Hisamoto
- Organizer
  19th International C.elegans meeting
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] Regulation of axon regeneration via a JNK pathway in C. elegans.2012
- Author(s)
  久本直毅
- Organizer
  日本神経科学学会
- Place of Presentation
  名古屋国際会議場 (愛知県)
- Data Source
  KAKENHI-PROJECT-23590331
[Presentation] Regulation of axon regeneration via a JNK pathway in C. elegans.2012
- Author(s)
  久本直毅
- Organizer
  日本神経科学学会
- Place of Presentation
  名古屋国際会議場 (愛知県)
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PUBLICLY-23117708
[Presentation] MAPキナーゼホスファターゼによる神経軸索再生制御2011
- Author(s)
  久本直毅
- Organizer
  日本生化学会
- Place of Presentation
  京都国際会館(招待講演)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PUBLICLY-23117708
[Presentation] 線虫新規増殖因子SVH-1とその受容体チロシンキナーゼSVH-2はJNK型MAPK経路を介して神経軸索再生を制御する2011
- Author(s)
  李春,久本直毅, Nix Paola,金尾朱夏,水野智亮, Bastiani Michael,松本邦弘
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21247031
[Presentation] WNK-1 negatively regulates formation of diacylglycerol in C. elegans2011
- Author(s)
  福薗嵩,久本直毅,松本邦弘
- Organizer
  18th International C. elegans Meeting
- Place of Presentation
  アメリカUniversity of California
- Data Source
  KAKENHI-PROJECT-21247031
[Presentation] MAPキナーゼホスファターゼによる神経軸索再生制御2011
- Author(s)
  久本直毅
- Organizer
  日本生化学会(招待講演)
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23590331
[Presentation] 線虫をモデル動物とした神経再生を誘導する因子/受容体の解析2010
- Author(s)
  李春、水野智亮、久本直毅、松本邦弘
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21247031
[Presentation] The Chaperone Complex BAG2-HSC70/HSP70 determines localization of C. elegans leucine-repeat kinase LRK-1 in the regulation of Axonal-Dendritic Polarity.
- Author(s)
  Alam T, Fukuzono T, Pastuhov, SI, Fukushima O, Li C, Hattori A, Hanafusa H, Matsumoto K, Hisamoto N.
- Organizer
  Society for Neuroscience 2014
- Place of Presentation
  Wasington, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] セロトニン-Rho/cAMPシグナル伝達経路による神経軸索再生の制御機構
- Author(s)
  丸山　裕生、Tanimul Alam、Paola Nix、Michael Bastiani、久本　直毅、松本　邦弘
- Organizer
  日本分子生物学会第３６回年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] Identification of two endocannabinoid receptors involved in regulation of axon regeneration in C.elegans
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] 糖鎖修飾因子群による神経軸索再生制御
- Author(s)
  加藤優桂、久本直毅、松本邦弘
- Organizer
  日本分子生物学会第３６回年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] セロトニン-Rho/cAMPシグナル伝達経路による神経軸索再生の制御機構
- Author(s)
  丸山　裕生、Tanimul Alam、Paola Nix、Michael Bastiani、久本　直毅、松本　邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] セロトニン-Rho/cAMPシグナル伝達経路による神経軸索再生の制御機構
- Author(s)
  丸山　裕生、Tanimul Alam、Paola Nix、Michael Bastiani、久本　直毅、松本　邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] SVH-5 transcription factor regulates axon regeneration in C. elegans by activating the transcription of the svh-2 gene encoding a receptor tyrosine kinase.
- Author(s)
  Chun Li, Naoki Hisamoto, Kunihiro Matsumoto
- Organizer
  The 6th Asia-Pacific C. elegans meeting and C. elegans topic meeting on Development, Cell Biology and Gene Expression Meeting
- Place of Presentation
  California, USA
- Year and Date
  2014-07-15 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Identification of endocannabinoid receptors regulating axon regeneration in C.elegans
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  6th international conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  Tokyo, JAPAN
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] Endocannabinoid AEA as injury signal in axon regeneration.
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  2013 FASEB Summer Research Conference on Lysophospholipid and Other Related Mediators
- Place of Presentation
  Niseko, Hokkaido, JAPAN
- Year and Date
  2014-08-04 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] 線虫HGF/プラスミノーゲン様タンパク質SVH-1は増殖因子としてだけではなく細胞外マトリクスを調節するプロテアーゼとしても機能する
- Author(s)
  久本直毅、李春、吉田誠希、松本邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] SVH-5 transcription factor regulates axon regeneration in C. elegans by activating the transcription of the svh-2 gene encoding a receptor tyrosine kinase.
- Author(s)
  Chun Li, Naoki Hisamoto, Kunihiro Matsumoto
- Organizer
  The 6th Asia-Pacific C. elegans meeting and C. elegans topic meeting on Development, Cell Biology and Gene Expression Meeting
- Place of Presentation
  Nara, JAPAN
- Year and Date
  2014-06-15 – 2014-06-19
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] 線虫HGF/プラスミノーゲン様タンパク質SVH-1は増殖因子としてだけではなく細胞外マトリクスを調節するプロテアーゼとしても機能する
- Author(s)
  久本直毅、李春、吉田誠希、松本邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Identification of two endocannabinoid receptors involved in regulation of axon regeneration in C.elegans
- Author(s)
  Strahil Pastuhov, Naoki Hisamoto, Kunihiro Matsumoto
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Rhoシグナル伝達経路はミオシン軽鎖のリン酸化を介して線虫の神経軸索再生を制御する
- Author(s)
  アラム　タニムル、久本　直毅、松本　邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Identification of two endocannabinoid receptors involved in regulation of axon regeneration in C.elegans
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  日本分子生物学会第３６回年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] 糖鎖修飾因子群による神経軸索再生制御
- Author(s)
  加藤優桂、久本直毅、松本邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] SVH-5 transcription factor regulates axon regeneration in C. elegans by activating the transcription of the svh-2 gene encoding a receptor tyrosine kinase.
- Author(s)
  Li C, Hisamoto N, Matsumoto K.
- Organizer
  The 6th Asia-Pacific C. elegans meeting and C. elegans topic meeting on Development, Cell Biology and Gene Expression Meeting
- Place of Presentation
  Nara, JAPAN
- Year and Date
  2014-06-15 – 2014-06-19
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] The Chaperone Complex BAG2-HSC70/HSP70 determines localization of C. elegans leucine-repeat kinase LRK-1 in the regulation of Axonal-Dendritic Polarity
- Author(s)
  Alam T, Fukuzono T, Pastuhov SI, Fukushima O, Li C, Hattori A, Hanafusa H, Matsumoto K, Hisamoto N.
- Organizer
  Society for Neuroscience 2014
- Place of Presentation
  Wasington, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] Endocannabinoid AEA as injury signal in axon regeneration.
- Author(s)
  Strahil Pastuhov, Naoki Hisamoto, Kunihiro Matsumoto
- Organizer
  2013 FASEB Summer Research Conference on Lysophospholipid and Other Related Mediators
- Place of Presentation
  Niseko, Hokkaido, JAPAN
- Year and Date
  2014-08-04 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Identification of endocannabinoid receptors regulating axon regeneration in C.elegans.
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  6th international conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  Tokyo, JAPAN
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] The Chaperone Complex BAG2-HSC70/HSP70 determines localization of C. elegans leucine-repeat kinase LRK-1 in the regulation of Axonal-Dendritic Polarity
- Author(s)
  Alam T, Fukuzono T, Pastuhov SI, Fukushima O, Li C, Hattori A, Hanafusa H, Matsumoto K, Hisamoto N.
- Organizer
  Society for Neuroscience 2014
- Place of Presentation
  Washington, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] Endocannabinoid AEA as injury signal in axon regeneration.
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  2013 FASEB Summer Research Conference on Lysophospholipid and Other Related Mediators
- Place of Presentation
  Niseko, Hokkaido, JAPAN
- Year and Date
  2014-08-04 – 2014-08-09
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] Identification of endocannabinoid receptors regulating axon regeneration in C.elegans.
- Author(s)
  Pastuhov SI, Hisamoto N, Matsumoto K.
- Organizer
  6th international conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  Tokyo, JAPAN
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-26293063
[Presentation] Rhoシグナル伝達経路はミオシン軽鎖のリン酸化を介して線虫の神経軸索再生を制御する
- Author(s)
  アラム　タニムル、久本　直毅、松本　邦弘
- Organizer
  日本分子生物学会第３６回年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] 線虫HGF/プラスミノーゲン様タンパク質SVH-1は増殖因子としてだけではなく細胞外マトリクスを調節するプロテアーゼとしても機能する
- Author(s)
  久本直毅、李春、吉田誠希、松本邦弘
- Organizer
  日本分子生物学会第３６回年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26640123
[Presentation] 糖鎖修飾因子群による神経軸索再生制御
- Author(s)
  加藤優桂、久本直毅、松本邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25116713
[Presentation] Rhoシグナル伝達経路はミオシン軽鎖のリン酸化を介して線虫の神経軸索再生を制御する
- Author(s)
  アラム　タニムル、久本　直毅、松本　邦弘
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25116713

1. HANAHUSA Hiroshi (00345844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. MATSUMOTO Kunihiro (70116375)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
3. NAKASHIMA Shigeru (60188935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. BANNO Yoshiko (50116852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 伊藤翼 (60978724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. PASTUHOV STRAHIL

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
7. NATSUME Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 白壁恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 武田弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 一條秀憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 西田栄介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 李春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 稲葉弘哲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. LI Chun

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 井上和秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 石原健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 伊佐正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 饗場篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HISAMOTO Naoki 久本 直毅

久本 直毅 ヒサモト ナオキ

Research Projects

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Co-Researchers

神経軸索再生を制御するシグナルネットワークの解明Principal Investigator

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透明魚を用いた血液脳関門の維持・破綻メカニズムの解明Principal Investigator

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神経軸索再生におけるオートファジー制御因子の役割Principal Investigator

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線虫をモデルとした神経軸索再生制御機構Principal Investigator

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切断軸索からのダイイングコードPrincipal Investigator

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Analysis of svh genes regulating axon regenerationPrincipal Investigator

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残存軸索断片が発信する神経軸索再生制御シグナルPrincipal Investigator

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遠位切断軸索からのダイイングコードPrincipal Investigator

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Regulation of axon regeneration in C. elegansPrincipal Investigator

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Global identification of factors acting with Parkinson disease/Alzheimer disease genes.Principal Investigator

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アナンダミドによる軸索再生抑制機構の解析Principal Investigator

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Mechanism of signal transduction regulating axon regeneration

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酸化ストレスセンサーによるＭＡＰＫカスケード活性化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

HISAMOTO Naoki 久本直毅

久本直毅ヒサモトナオキ