Kimura Yoko 木村洋子

… Alternative Names

KIMURA Yoko 木村洋子

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Researcher Number	80291152
Other IDs
External Links
Affiliation (Current)	2025: 静岡大学, 農学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 静岡大学, 農学部, 教授 2015 – 2017: 静岡大学, 農学部, 教授 2014: 静岡大学, (連合)農学研究科(研究院), 教授 2012 – 2013: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主任研究員 2011: (財)東京都医学総合研究所, 生体分子先端研究分野, 主任研究員 … More 2011: 財団法人東京都医学総合研究所, 生体分子先端研究分野, 主任研究員 2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 2002 – 2003: Tokyo Metropolitan Institute of Medical Science, Researcher, 東京都臨床医学総合研究所, 研究員 2000 – 2001: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1999: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1998: 財団法人東京都臨床医学総合研究所, 腫瘍細胞研究部門, 研究員 1997: (財)東京都臨床医学総合研究所, 腫瘍細胞研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / Cell biology / Basic Section 38060:Applied molecular and cellular biology-related / Basic Section 44010:Cell biology-related / Biological Sciences Except Principal Investigator Eating habits
Keywords	Principal Investigator ポリグルタミン / 分子シャペロン / 酵母 / 凝集体 / VCP / p97 / Hsp104 / 神経変性変異 / 出芽酵母 / 熱ストレス … More / ホメオスタシス / エンドソーム / 脱ユビキチン化酵素 / ユビキチン / Cdc48 / アミロイド / Cdc37 / Hfl1 / 陥入形成 / 相分離 / 形態変化 / 液胞 / Alix / Rfu1 / Bro1 / タンパク質分解 / 神経変性疾患 / cross-seeding / AAA superfamily蛋白質 / 酵母プリオン / コンフォーメーション / コンフォーメーション病 / タンパク質キナーゼ / Cdc28 / たんぱく質キナーゼ / Hsp90 / 核膜 / 膜 / 核 / Atg8 / 膜陥入 / 核膜孔複合体 / 陥入 / aggregates / AAA superfamily protein / amyloid / molecular chaperone / neurodegerative disease / polyglutamine / 構造変換 / AAA+ スーパーファミリー蛋白質 / AAAスーパーファミリー蛋白質 / V ドメイン / Ｒｉｍ２０ / Vドメイン / endosome / 熱ショックストレス / ubiquitin / Rsp5 / ユビキチンリガーゼ / 蛋白質分解 / Ufd3(Doa1) / VCP/Cdc48 / IBMPFD / ミトコンドリア / AAA+ superfamily蛋白質 / AAA+ Superfamily蛋白質 / 細胞障害性機構 / コンバージョン / hsp104 … More Except Principal Investigator ウイルス / IRF / 転写因子 / インターフェロン / 糖尿病 / 認知症 / 認知症予防 / カテキン / テアニン / 脳老化 / ストレス / コアクティベーター / サイトカイン / 培養細胞 / 転写制御 / 遺伝子制御 / ウイルス感染 / IFN Less

Analysis of morophological changes of vacuoles in resonse to chronic heat stressPrincipal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Shizuoka University
Cellular responses to chronic heat stress in yeastPrincipal Investigator
- Principal Investigator
  
  Kimura Yoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Shizuoka University
Mechanism of brain aging promotion by stress and diabetes mellitus and its prevention by food components
- Principal Investigator
  
  Keiko Unno
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  University of Shizuoka
Regulation of ubiquitin homeostasis at endosomesPrincipal Investigator
- Principal Investigator
  
  Kimura Yoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Shizuoka University
ユビキチンホメオスタシスの制御機構Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Funational analysis of Rfu1 that regulates ubiquitin homeostasisPrincipal Investigator
- Principal Investigator
  
  KIMURA Yoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
ポリグルタミンの凝集体形成、細胞障害におけるストレス蛋白質の役割Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ポリグルタミンの凝集体形成、細胞障害におけるストレス蛋白質の役割Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ポリグルタミンのアミロイド凝集体形成における分子シャペロンの役割Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
The Role of stress proteins in the aggregation and cytotoxicity of polyglutaminePrincipal Investigator
- Principal Investigator
  
  KIMURA Yoko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ポリグルタミンによる凝集体生成と細胞障害機構の解明Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
シャペロンCdc37の機能解析Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Cdc37と細胞内基質の相互作用の解析Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
転写因子IRF-3による細胞生理機能の制御
- Principal Investigator
  
  藤田尚志
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
分子シャペロンCdc37とその細胞内基質の相互作用の解析Principal Investigator
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
I型インターフェロン系で機能する転写抑制因子の解析
- Principal Investigator
  
  藤田尚志
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] タンパク質の品質管理と神経変性2014
- Author(s)
  木村洋子, 垣塚彰
- Publisher
  Annual Review 神経
- Data Source
  KAKENHI-PROJECT-23570184
[Book] Annual Review 神経　20142014
- Author(s)
  木村洋子　垣塚彰
- Total Pages
  6
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23570184
[Journal Article] Physicochemical properties of the vacuolar membrane and cellular factors determine formation of vacuolar invaginations2023
- Author(s)
  Kimura Yoko、Tsuji Takuma、Shimizu Yosuke、Watanabe Yuki、Kimura Masafumi、Fujimoto Toyoshi、Higuchi Miyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 16187-16187
- DOI
  10.1038/s41598-023-43232-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06818, KAKENHI-PROJECT-23K05145, KAKENHI-PUBLICLY-22H04654
[Journal Article] 熱ストレスによる酵母細胞の形態的、生理的変化と生存戦略2022
- Author(s)
  木村洋子
- Journal Title
  
  日本醸造協会誌
  
  Volume: 7 Pages: 446-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06620
[Journal Article] ストレスに対する液胞の形態変化2022
- Author(s)
  木村洋子
- Journal Title
  
  生体の科学
  
  Volume: 73 Pages: 230-234
- Data Source
  KAKENHI-PROJECT-20K06620
[Journal Article] 酵母細胞内のふるまいを観る2021
- Author(s)
  木村洋子
- Journal Title
  
  日本醸造協会誌
  
  Volume: 116 Pages: 133-133
- Data Source
  KAKENHI-PROJECT-20K06620
[Journal Article] S-Adenosylhomocysteine Analogue of a Fairy Chemical, Imidazole-4-carboxamide, as its Metabolite in Rice and Yeast and Synthetic Investigations of Related Compounds2021
- Author(s)
  Hitoshi Ouchi , Takuya Namiki , Kenji Iwamoto , Nobuo Matsuzaki , Makoto Inai , Mihaya Kotajima , Jing Wu , Jae-Hoon Choi , Yoko Kimura , Hirofumi Hirai , Xiaonan Xie , Hirokazu Kawagishi , Toshiyuki Kan
- Journal Title
  
  J Nat Prod .
  
  Volume: 84 Issue: 2 Pages: 453-458
- DOI
  10.1021/acs.jnatprod.0c01269
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06620, KAKENHI-PROJECT-18K05452, KAKENHI-PROJECT-19K05460, KAKENHI-PROJECT-20K15958, KAKENHI-PROJECT-20H05620
[Journal Article] Conserved Mode of Interaction between Yeast Bro1 Family V Domains and YP(X)nL Motif-Containing Target Proteins2015
- Author(s)
  Yoko Kimura, Mirai Tanigawa, Junko Kawawaki, Kenji Takagi, Tsunehiro Mizushima, Tatsuya Maeda, Keiji Tanaka
- Journal Title
  
  Eukaryotic Cell
  
  Volume: 14 Issue: 10 Pages: 976-982
- DOI
  10.1128/ec.00091-15
- NAID
  120005671359
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440070, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-25291042, KAKENHI-PROJECT-26000014
[Journal Article] Ubiquitin is phosphorylated by PINK1 to activate parkin.2014
- Author(s)
  Koyano, F., Okatsu, K., Kosako, H., Tamura, Y., Go, E., Kimura, M., Kimura, Y., Tsuchiya, H., Yoshihara, H., Hirokawa, T., Endo, T., Fon. E. A., Trempe, J. F., Saeki, Y., Tanaka, K., and Matsuda, N.
- Journal Title
  
  Nature
  
  Volume: 510(in press) Issue: 7503 Pages: 162-166
- DOI
  10.1038/nature13392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23570231, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24657072, KAKENHI-PUBLICLY-25112522, KAKENHI-PROJECT-25870311, KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26440070, KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-22227003
[Journal Article] The ESCRT-III adaptor protein Brol controls functions of regulator for free ubiauitin chains 1 (Rful) in ubiquitin homeostasis2014
- Author(s)
  Kimura Y, Kawawaki J, Kakiyama Y, Shimoda A, and Tanaka K
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 31 Pages: 21760-21769
- DOI
  10.1074/jbc.m114.550871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-26440070
[Journal Article] Different dynamic movements of wild-type and pathogenic VCPs and their cofactors to damaged mitochondria in a Parkin-mediated mitochondrial quality control system2013
- Author(s)
  Kimura Y, Fukushi J., Hori S., Matsuda N., Okatsu K. Kakiyama Y., Kawawaki J. Kakizuka A., and Tanaka K.
- Journal Title
  
  Genes to Cells
  
  Volume: 18 Pages: 1131-1143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570184
[Journal Article] Different dynamic movements of wild-type and pathogenic VCPs and the ir cofactors to damaged mitochondria in a Parkin-mediated mitochondrial quality control system2013
- Author(s)
  Yoko Kimura, Junpei Fukushi, Seiji Hori, Noriyuki Matsuda, Kei Okatsu, Yukie Kakiyama, Junko Kawawaki, Akira Kakizuka, Keiji Tanaka
- Journal Title
  
  Genes to Cells
  
  Volume: 18 Issue: 12 Pages: 1131-43
- DOI
  10.1111/gtc.12103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-23570184
[Journal Article] Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model2012
- Author(s)
  Weiss K, Kimura Y, Lee W, and Littleton T.
- Journal Title
  
  Genetics
  
  Volume: 190 Pages: 581-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570184
[Journal Article] Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington’s disease model.2012
- Author(s)
  Weiss K, Kimura Y., Lee W, and Littleton T.
- Journal Title
  
  Genetics
  
  Volume: 190 Issue: 2 Pages: 581-600
- DOI
  10.1534/genetics.111.133710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570184, KAKENHI-PUBLICLY-23117529
[Journal Article] Rescue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs2012
- Author(s)
  Takata T, Kimura Y, Ohnuma Y, Kawawaki J, Kakiyama Y, Tanaka K, and Kakizuka A.
- Journal Title
  
  J. Struct. Biol.
  
  Volume: 179 Pages: 93-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570184
[Journal Article] Rescue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs.2012
- Author(s)
  Takata T et al.
- Journal Title
  
  J. Str. Biology
  
  Volume: 173 Issue: 2 Pages: 93-103
- DOI
  10.1016/j.jsb.2012.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-23570184, KAKENHI-PUBLICLY-23117529
[Journal Article] 脱ユビキチン化酵素酵素の制御機構2011
- Author(s)
  木村洋子
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 1945-1949
- Data Source
  KAKENHI-PUBLICLY-23117529
[Journal Article] 脱ユビキチン化酵素の制御機構2011
- Author(s)
  木村洋子
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 1945-1949
- Data Source
  KAKENHI-PROJECT-23570184
[Journal Article] The role of preexisting aggregates in Hsp104-dependent polyglutamine aggregate formation and epifenetic change of yeast prion2004
- Author(s)
  Kimura, Y., Koitabshi, S., Kakizuka, A., Fujita, T.
- Journal Title
  
  Genes to Cells 9
  
  Pages: 685-696
- Data Source
  KAKENHI-PROJECT-16015338
[Journal Article] ポリグルタミン病における分解系システムの役割2004
- Author(s)
  木村洋子
- Journal Title
  
  実験医学 22
  
  Pages: 293-297
- Data Source
  KAKENHI-PROJECT-15032262
[Journal Article] ポリグルタミン凝集体形成機構2004
- Author(s)
  木村洋子
- Journal Title
  
  蛋白質核酸酵素 49
  
  Pages: 1122-1123
- Data Source
  KAKENHI-PROJECT-16015338
[Journal Article] ポリグルタミン病における分解系システムの役割2004
- Author(s)
  木村洋子
- Journal Title
  
  実験医学 22
  
  Pages: 293-297
- Data Source
  KAKENHI-PROJECT-16015338
[Journal Article] The role of preexisting aggregates in Hsp104-dependent polyglutamine aggregate formation and epifenetic change of yeast prion2004
- Author(s)
  Kimura, Y., Koitabshi, S., Kakizuka, A., Fujita, T.
- Journal Title
  
  Genes to Cells 9
  
  Pages: 685-696
- Data Source
  KAKENHI-PROJECT-15032262
[Journal Article] ポリグルタミン凝集体形成機構2004
- Author(s)
  木村洋子
- Journal Title
  
  蛋白質核酸酵素 49
  
  Pages: 1122-1123
- Data Source
  KAKENHI-PROJECT-15032262
[Journal Article] Polyglutamine diseases and molecular chaperones.2003
- Author(s)
  Kimura, Kakizuka.
- Journal Title
  
  IUBMB Life. 55
  
  Pages: 337-345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] Analysis of yeast prion aggregates with amyloid-staining compound in vivo.2003
- Author(s)
  Kimura et al.
- Journal Title
  
  Cell Struc. Func. 28
  
  Pages: 187-193
- NAID
  10011619544
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] Analysis of yeast piron aggregates with amyloid-staining compound in vivo.2003
- Author(s)
  Kimura Y., et al.
- Journal Title
  
  Cell Struc. Func. 28
  
  Pages: 187-193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] Polyglutamine diseases and molecular chaperones2003
- Author(s)
  Kimura et al.
- Journal Title
  
  IUBMB Life 55
  
  Pages: 337-345
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] Circumvention of chaperone requirement for aggregate formation of a short polyglutamine tract by the co-expression of a long polyglutamine tract.2002
- Author(s)
  Kimura Y, et al.
- Journal Title
  
  J.Biol.Chem. 277
  
  Pages: 37536-37541
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] Circumvention of chaperone requirement for aggregate formation of a short polyglutamine tract by the co-expression of a long polyglutamine tract2002
- Author(s)
  Kimura Y. et al.
- Journal Title
  
  J. Biol. Chem. 277
  
  Pages: 37536-37541
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] ポリグルタミン病と分子シャペロン2002
- Author(s)
  木村洋子
- Journal Title
  
  神経研究の進歩 46
  
  Pages: 697-703
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] Polyglutamine-byo to bunshi-shaperon.2002
- Author(s)
  Kimura Y.
- Journal Title
  
  Shinkei-kenkyu no shinpo 46
  
  Pages: 697-703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] T : Initial process of polyglutamine aggregate formation in vivo.2001
- Author(s)
  Kimura Y, et al.
- Journal Title
  
  Genes Cells 6
  
  Pages: 887-897
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Journal Article] Initial process of polyglutamine aggregate formation in vivo.2001
- Author(s)
  Kimura Y, et al.
- Journal Title
  
  Genes Cells 6
  
  Pages: 887-897
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Presentation] 出芽酵母におけるユビキチン・プロテアソーム系による核膜孔複合体の品質管理2023
- Author(s)
  清水翔太、清水直樹、服部里菜、木村洋子
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 熱ストレス時の核膜孔複合体の品質管理2023
- Author(s)
  清水翔太、清水直樹、山田龍明、木村洋子
- Organizer
  第15回日本臨床ストレス応答学会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] Physicochemical properties of the vacuolar membrane and cellular factors determine formation of vacuolar invaginations2023
- Author(s)
  Yoko Kimura, Takuma Tsuji, Yousuke Shimizu, Masafumi Kimura, Toyoshi Fujimoto, Miyuki Higuchi
- Organizer
  Cold Spring Harbor Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] Atg8結合液胞膜タンパク質Hfl1の液胞融合における新規機能解析2023
- Author(s)
  安藤亮汰、木村洋子
- Organizer
  酵母遺伝学フォーラム第56回研究報告会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 熱ストレスによる酵母液胞の形態と機能変化の解析2023
- Author(s)
  清水耀介、木村将文、木村洋子
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 亜致死的熱ストレスに対するSaccharomyces cerevisiaeの緩和応答の解析2023
- Author(s)
  大場由美子、加藤拓、只見秀代、木村洋子
- Organizer
  酵母遺伝学フォーラム第56回研究報告会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 出芽酵母の液胞膜ホメオスタシス制御機構の解明2023
- Author(s)
  木村将文、清水耀介、木村洋子
- Organizer
  酵母遺伝学フォーラム第56回研究報告会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 持続的熱ストレス時の核膜孔複合体の品質管理2023
- Author(s)
  清水翔太、清水直樹、服部里菜、木村洋子
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 出芽酵母における浸透圧ストレスによる熱耐性獲得機構の解明2023
- Author(s)
  大場由美子、加藤拓、只見秀代、木村洋子
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 熱ストレス時におけるユビキチン・プロテアソーム系による核膜孔複合体の品質管理2023
- Author(s)
  清水翔太、清水直樹、服部里菜、木村洋子
- Organizer
  酵母遺伝学フォーラム第56回研究報告会
- Data Source
  KAKENHI-PROJECT-23K05145
[Presentation] 持続的熱ストレスに対する酵母ミトコンドリア脆弱性の解明2022
- Author(s)
  高橋直花、木村洋子
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 出芽酵母におけるユビキチン・プロテアソーム系による熱ストレス時の核膜孔複合体の品質管理2022
- Author(s)
  清水翔太、服部里菜、清水直樹、木村洋子
- Organizer
  日本臨床ストレス応答学会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 熱ストレス時の酵母液胞の形態変化2022
- Author(s)
  清水耀介、辻琢磨、木村将文、藤本豊士、木村洋子
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 液胞膜陥入形成に関与するAtg8結合タンパク質Hfl1の解析2022
- Author(s)
  渡邊祐希、樋口美由紀、木村洋子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 熱ストレス時の液胞膜とその動態の解析2022
- Author(s)
  渡邊祐希、辻　琢磨、樋口美由紀、藤本豊士、木村洋子
- Organizer
  酵母遺伝学フォーラム
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 出芽酵母のおけるユビキチン・プロテアソーム系による熱ストレス時の核膜孔複合体の品質管理2022
- Author(s)
  清水翔太、服部里菜、木村洋子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 酵母における持続的な熱ストレス時の液胞形態変化と液胞膜ホメオスタシス制御機構の解析2021
- Author(s)
  木村洋子
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] ICAの代謝産物であるS-ICAr-Hの存在意義についての研究2021
- Author(s)
  古田島美颯、崔宰熏、呉静、謝肖男、木村洋子、道羅英夫、大西利幸、平井浩文、浅川倫宏、大内仁志、稲井誠、菅敏幸、河岸洋和
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 持続的な熱ストレス時の細胞内変化と機能制御2021
- Author(s)
  木村洋子
- Organizer
  第23回酵母合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 持続的な熱ストレスによる出芽酵母の液胞の形態変化2020
- Author(s)
  木村洋子
- Organizer
  第９３日本生化学会年会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 持続的な熱ストレス時の液胞の形態変化と液胞形態維持機構の解明2020
- Author(s)
  小山彩・林加奈・石井彩音・渡邊祐希・高橋直花・木村洋子
- Organizer
  酵母遺伝学フォーラム第53回研究報告会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 液胞の形態変化からみる熱ストレス応答と液胞膜ホメオスタシス2020
- Author(s)
  木村洋子
- Organizer
  Biothermology Workshop 2020
- Invited
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] 酵母Alixファミリータンパク質とその標的タンパク質との特異的相互作用の解析2020
- Author(s)
  浅川琴美、木村洋子
- Organizer
  日本生化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-20K06620
[Presentation] Green soybean extracts increases neuritogenesis in SH-SY5Y cells and BDNF expression in mouse brain2018
- Author(s)
  Monira Pervin, Keiko Unno, Yuya Nakayama, Hiroyuki Ikemoto, Shinjiro Imai, Kazuaki Iguchi, Akira Minami, Yoko Kimura, Yoriyuki Nakamura
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K00828
[Presentation] Analysis of interaction between yeast Bro1 family V domains and YP(X)nL motif-containing target proteins2016
- Author(s)
  Yoko Kimura
- Organizer
  14th International Congress on Yeasts
- Place of Presentation
  Awaji Yumebudai, Awaji, Hyogo, Japan
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440070
[Presentation] Suppression of cognitive dysfunctionby green tea catechin2015
- Author(s)
  Monira Pervin, Aimi Nakagawa, Aya Hara, Fumio Nanjo, Shinjiro Imai, Yoko Kimura, Yuriyuki Nakamura, Keiko Unno
- Organizer
  19th International Conference of Functional Food Center
- Place of Presentation
  Kobe, Japan
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00828
[Presentation] Conserved Mode of Interaction between Yeast Bro1 Family V Domains and YP(X)nL Motif-Containing Target Proteins2015
- Author(s)
  Yoko Kimura, Mirai Tanigawa, Junko Kawawaki, Kenji Takagi, Tsunehiro Mizushima, Tatsuya Maeda, Keiji Tanaka
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（神戸市中央区）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440070
[Presentation] 酵母Bro1およびRim20のV ドメインの解析2015
- Author(s)
  木村　洋子、谷川美頼、川脇純子、高木賢治、水島恒裕、前田達哉・田中啓二
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  広島大学〈広島県東広島市）
- Year and Date
  2015-08-31
- Data Source
  KAKENHI-PROJECT-26440070
[Presentation] ユビキチンホメオスタシスの制御機構2013
- Author(s)
  木村洋子
- Organizer
  第86回日本生化学会大会シンポジウム「タンパク質の品質管理と疾患」
- Place of Presentation
  横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Dynamics of normal and pathogenic p97/VCP upon mitochondria stress2013
- Author(s)
  Yoko Kimura, Akira Kakizuka, and Keiji Tanaka.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-23117529
[Presentation] 単量体ユビキチンの量を制御するRfu1の局在と分解はBro1に依存している2013
- Author(s)
  木村洋子, 川脇純子, 柿山幸恵, 田中啓二
- Organizer
  第46回酵母遺伝学フォーラム
- Place of Presentation
  仙台
- Year and Date
  2013-09-10
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Dynamics of normal and pathogenic p97/VCP upon mitochondria stress2013
- Author(s)
  Yoko Kimura, Akira Kakizuka, and Keiji Tanaka.
- Organizer
  1^<st> International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  Tokyo Japan
- Year and Date
  2013-02-01
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] ミトコンドリアストレスにおける変異VCPの動態解析2012
- Author(s)
  木村洋子, 垣塚彰, 田中啓二
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] 疾患型VCPは酵母cdc48変異体の増殖欠損を抑圧する2012
- Author(s)
  高田尚寛、木村洋子、大沼洋平、川脇純子、柿山幸恵、田中啓二、垣塚彰
- Organizer
  第45回酵母遺伝学フォーラム
- Place of Presentation
  京都
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PUBLICLY-23117529
[Presentation] ミトコンドリアストレスにおける正常型と疾患型VCPの動態変化2012
- Author(s)
  木村洋子, 田中啓二
- Organizer
  新学術領域「修飾シグナル病」研究交流会
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] ミトコンドリアストレスにおけるVCPの動態解析2012
- Author(s)
  木村洋子
- Organizer
  学術領域[修飾シグナル病]若手ワークショップ
- Place of Presentation
  湯河原
- Data Source
  KAKENHI-PUBLICLY-23117529
[Presentation] ミトコンドリアストレスにおける変異VCPの動態解析2012
- Author(s)
  木村洋子、垣塚彰　田中啓二
- Organizer
  第８５回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PUBLICLY-23117529
[Presentation] ミトコンドリアストレスにおけるVCPの動態解析2012
- Author(s)
  木村洋子
- Organizer
  新学術領域[修飾シグナル病]若手ワークショップ
- Place of Presentation
  湯河原
- Year and Date
  2012-10-04
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Rescue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs2012
- Author(s)
  Kimura Y., Takata, T., Kakizuka A., and Tanaka K.
- Organizer
  FASEB Summer Research Conference(Ubiquitin and Cellular Regulation)Vermont Academy
- Place of Presentation
  Saxtons River, Vermont, USA
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Rescue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs2012
- Author(s)
  Kimura Y., Takata, T., Kakizuka A., and Tanaka K.
- Organizer
  FASEB Summer Research Conference　（Ubiquitin and Cellular Regulation）
- Place of Presentation
  Saxtons River, Vermont, USA
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] 疾患型VCPは酵母cdc48変異体の増殖欠損を抑圧する2012
- Author(s)
  高田尚寛, 木村洋子, 大沼洋平, 川脇純子, 柿山幸恵, 田中啓二, 垣塚彰
- Organizer
  第45回酵母遺伝学フォーラム
- Place of Presentation
  京都
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] escue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs.2012
- Author(s)
  Kimura Y., Takata, T., Kakizuka A., and Tanaka K.
- Organizer
  FASEB Summer Research Conference　（Ubiquitin and Cellular Regulation）
- Place of Presentation
  Vermont Academy, Saxtons River, Vermont, USA
- Year and Date
  2012-06-24
- Data Source
  KAKENHI-PUBLICLY-23117529
[Presentation] 単量体のユビキチン量を制御する因子Rfu1の制御機構2011
- Author(s)
  木村洋子、川脇純子、下田鮎美、柿山幸恵、田中啓二
- Organizer
  第44回酵母遺伝学フォーラム
- Place of Presentation
  福岡
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PUBLICLY-23117529
[Presentation] Dynamics of normal and pathogenic p97/VCP upon mitochondira stress2011
- Author(s)
  Yoko Kimura, Akira Kakizuka Keiji Tanaka
- Organizer
  The 9th International Conference on AAA proteins
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Regulatory mechanism of ubiquitin homeostasis2011
- Author(s)
  木村洋子
- Organizer
  「奈良先端未来開拓コロキウム」シンポジウム
- Place of Presentation
  奈良先端科学技術大学
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Dynamics of normal and pathogenic p97/VCP upon mitochondira stress2011
- Author(s)
  Yoko Kimura, Akira Kakizuka Keiji Tanaka
- Organizer
  The 9th International Conference on AAA proteins
- Place of Presentation
  熊本
- Year and Date
  2011-11-09
- Data Source
  KAKENHI-PUBLICLY-23117529
[Presentation] 単量体のユビキチン量を制御する因子Rfu1の制御機構2011
- Author(s)
  木村洋子, 川脇純子, 下田鮎美, 柿山幸恵, 田中啓二
- Organizer
  第44会酵母遺伝学フォーラム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] ユビキチンホメオスタシスの制御機構2011
- Author(s)
  木村洋子
- Organizer
  新学術領域「修飾シグナル病」第一回領域推進会議
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] ユビキチンホメオスタシスの制御機構2011
- Author(s)
  木村洋子
- Organizer
  新学術領域「修飾シグナル病」第2回研究交流
- Place of Presentation
  東京大学 (若手ポスター発表会)
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Dynamics of normal and pathogenic p97/VCP upon mitochondria stress Oral presentation2011
- Author(s)
  Yoko Kimura , Akira Kakizuka , and Keiji Tanaka.
- Organizer
  The 9^<th> International Conference on AAA proteins
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2011-11-09
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Regulatory mechanism of ubiquitin homeostasis2011
- Author(s)
  木村洋子
- Organizer
  「奈良先端未来開拓コロキウム」シンポジウム(招待講演)
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] ミトコンドリアストレスにおける変異VCPの動態解析
- Author(s)
  木村洋子、垣塚彰　田中啓二
- Organizer
  第８５回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] Dynamics of normal and pathogenic p97/VCP upon mitochondria stress
- Author(s)
  Yoko Kimura, Akira Kakizuka, and Keiji Tanaka.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23570184
[Presentation] VCP/Cdc48過剰発現スクリーニングから得られたgpi10変異体の解析
- Author(s)
  大沼洋平・木村洋子・川脇純子・田中啓二・垣塚彰
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  東京大学・東京
- Year and Date
  2014-09-01 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-26440070
[Presentation] エンドソーム関連タンパク質Bro1とユビキチンの量的制御因子Rfu1の相互作用の解析
- Author(s)
  A1木村洋子.川脇純子.田中啓二
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜・横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26440070
[]

1. KAKIZUKA Akira (80204329)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. 藤田尚志 (10156870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 米山光俊 (40260335)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Keiko Unno (10106437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 住吉晃 (80612530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ISHII Sanae

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. PERVIN Monira

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. NAKAMURA Yoriyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 田中啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 辻琢磨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Yoko 木村 洋子

KIMURA Yoko 木村 洋子

Research Projects

Research Products

Co-Researchers

Analysis of morophological changes of vacuoles in resonse to chronic heat stressPrincipal Investigator

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Cellular responses to chronic heat stress in yeastPrincipal Investigator

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Mechanism of brain aging promotion by stress and diabetes mellitus and its prevention by food components

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Regulation of ubiquitin homeostasis at endosomesPrincipal Investigator

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ユビキチンホメオスタシスの制御機構Principal Investigator

Principal Investigator

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Funational analysis of Rfu1 that regulates ubiquitin homeostasisPrincipal Investigator

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ポリグルタミンの凝集体形成、細胞障害におけるストレス蛋白質の役割Principal Investigator

Principal Investigator

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ポリグルタミンの凝集体形成、細胞障害におけるストレス蛋白質の役割Principal Investigator

Principal Investigator

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ポリグルタミンのアミロイド凝集体形成における分子シャペロンの役割Principal Investigator

Principal Investigator

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The Role of stress proteins in the aggregation and cytotoxicity of polyglutaminePrincipal Investigator

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ポリグルタミンによる凝集体生成と細胞障害機構の解明Principal Investigator

Principal Investigator

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シャペロンCdc37の機能解析Principal Investigator

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Cdc37と細胞内基質の相互作用の解析Principal Investigator

Principal Investigator

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Kimura Yoko 木村洋子

KIMURA Yoko 木村洋子

[Book] Annual Review 神経　20142014