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TAKAHASHI Yoshiki  高橋 芳樹

ORCIDConnect your ORCID iD *help
… Alternative Names

高橋 芳樹  タカハシ ヨシキ

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Researcher Number 80292019
External Links
Affiliation (based on the past Project Information) *help 2005: 医薬品食品衛生研, 研究員
2003: 国立医薬品食品衛生研究所, 療品部, 研究員
2002: 北海道大学, 大学院・薬学研究科, 助手
1998 – 2000: 北海道大学, 大学院・薬学研究科, 助手
Review Section/Research Field
Principal Investigator
Environmental pharmacy / Environmental pharmacy / Biological pharmacy
Except Principal Investigator
Biological pharmacy / 応用薬理学・医療系薬学 / Environmental pharmacy
Keywords
Principal Investigator
Xenobiotic-responsive element / receptor / Aryl hydrocarbon / DNAのメチル化 / 異物応答配列 / 芳香族炭化水素受容体 / プロモータ / STAT5 / 性差 / クロマチン / CYP2C12 … More
Except Principal Investigator
… More P450 / チトクロームP450 / CYP3A4 / 薬物代謝 / トランスジェニックマウス / EBPα / C / p53 / CYP3A7 / poor metabolizer / CYP2D6 / gene analysis / genetic polymorphism / 遺伝子解析 / 遺伝的多型 / FMO / 発現系 / 遺伝子多型 / サルモネラ菌 / 代謝的活性化 / transgenic mouse / gene regulation / development / fetal toxicity / 時期特異的発現調節 / 個人差 / 発現調節 / ヒト肝 / CYP3A5 / 胎児 / 転写制御 / 発生 / 胎児毒性 / DRUG DEVELOPMENT / RECOMBINANT / DRUG INTERACTION / DRUG METANBOISM / INHIBITION / PLATE READER / HIGH THROUGH PUT / 水溶性ポリマー / 薬物間相互作用 / チトクロームb_5 / 大腸菌発現系 / ハイスループットシステム / 医薬品開発 / 遺伝子組換え / 薬物相互作用 / 阻害 / プレートリーダー / ハイスループット / CYP2D6^*36 / Adverse reaction / cytochrome P450 / drug metabolism / フレームシフト型変異 / CYP2D6^*10C / 遺伝的解析 / 薬の効き過ぎ / CYP2D6*36 / 薬の効きすぎ / human genome / heterologous expression / gene therapy / genetic disease / trimethylamine / 代謝欠損 / クローニング / ノックアウトマウス / ヒトゲノム / 異種細胞発現系 / 遺伝子治療 / 遺伝病 / トリメチルアミン / Lung cancer / Genetic polymorphism / Metabolic activation / Mutation assay / Salmonella typhimurium / P450アロマターゼ / がん原物質活性化 / 遺伝子導入マウス / Ahレセプター / アロマターゼ / CYP1A2 / CYP1A1 / 発現制御 / DNAアダクト / がん原物質 / 肺がん / 変異原性試験 / 寿命制御遺伝子 / 遺伝子欠損型多型 / ニコチン / 肺がんリスク / 煙草 / ニトロソアミン / ヒト型マウス / タバコ / CYP2A6 / がん Less
  • Research Projects

    (9 results)
  • Co-Researchers

    (15 People)
  •  新規なイントロン由来アンチセンスプロモーターによるダイオキシン受容体の発現制御Principal Investigator

    • Principal Investigator
      高橋 芳樹
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  クロマチン構造の変化に由来するCYPの性特異的発現調節Principal Investigator

    • Principal Investigator
      高橋 芳樹
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Institute of Health Sciences
      Hokkaido University
  •  CYP2A6のpharmacogenomics的研究

    • Principal Investigator
      KAMATAKI Tetsuya
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hokkaido University
  •  Transcriptional regulation of the CYP3A7 gene specifically expressed in the human fetal liver.

    • Principal Investigator
      KAMATAKI Tetsuya
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Metabolic activation of procarcinogens and cancer risk

    • Principal Investigator
      KAMATAKI Tetsuya
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  ANALYSIS OF GENE MUTATION IN THAI CAUSING FISH ODOR SYNDROME

    • Principal Investigator
      KAMATAKL Tetsuya
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Developmental study for effective high-through-put screening system for new drug registration

    • Principal Investigator
      KAMATAKI Tetsuya
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Molecular mechanism (s) responsible for species difference in dioxin toxicityPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Yoshiki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hokkaido University
  •  GENETIC POLYMORPHISM OF DRUG METABOLIZING-ENZYME ; ANALYSIS OF NOVEL POLYMORPHISM AND DEVELOPMENT OF GENOTYPING METHOD

    • Principal Investigator
      ARIYOSHI Noritaka
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      HOKKAIDO UNIVERSITY
  • 1.  FUJITA Ken-ichi (60281820)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  ARIYOSHI Noritaka (00243957)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  KAMATAKI Tetsuya (00009177)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  NAKAYAMA Kazuo (20261323)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  YAMAZAKI Hiroshi (30191274)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KAMIDATE Tamio (70185990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  江角 浩安 (70160364)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  島田 力 (50158961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  船江 良彦 (00047268)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  杉山 雄一 (80090471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  川尻 要 (50142112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  原田 信広 (00189705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MINE Tsuyoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KOBAYASHI Satoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  UJJIN Pailin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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