YUHKI koh-ichi 結城幸一

… Alternative Names

Yuhki Koh-ichi 結城幸一

YUHKI Koh-ichi 結城幸一

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Researcher Number	80302420
Other IDs
Affiliation (Current)	2025: 旭川医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2022: 旭川医科大学, 医学部, 准教授 2011 – 2014: 旭川医科大学, 医学部, 准教授 2006 – 2011: 旭川医科大学, 医学部, 講師 2000 – 2006: 旭川医科大学, 医学部, 助手 1999: 筑波大学, 臨床医学系, 助手
Review Section/Research Field	Principal Investigator General pharmacology / Circulatory organs internal medicine / Basic Section 47040:Pharmacology-related / Circulatory organs internal medicine Except Principal Investigator General pharmacology / Pathological medical chemistry / Basic Section 47040:Pharmacology-related / Pathological medical chemistry / Circulatory organs internal medicine
Keywords	Principal Investigator 受容体欠損マウス / プロスタノイド / 心筋梗塞 / 虚血-再灌流障害 / プロスタグランジン / トロンボキサン / 心筋細胞 / 心不全 / 非アルコール性脂肪肝炎 / Ischemia-reperfusion injury … More / Receptor knock out mice / Myocardial infarction / Prostanoid / プロスタグラシン / 虚血-再灌流 / プレコンディショニング / プロスタグランジンE_2 / 再灌流障害 / 心筋虚血 / 虚血-再潅流 / 心肥大 / 心筋虚血-再灌流障害 / エネルギー代謝不全 / エンドセリン … More Except Principal Investigator プロスタノイド / プロスタグランジン / トロンボキサン / 線維化 / 心臓 / 心筋梗塞 / 循環器 / プロスタグランジンI_2 / マウス / 心肥大 / 心筋リモデリング / NASH / mice / cardiac remodeling / cardiac fibrosis / cardiac hypertrophy / prostanoid receptors / prostaglandin I_2 / prostanoids / プロスタグランジン I_2 / 受容体 / thromboxane / prostaglandin / prostanoid / 虚血・再潅流 / 血管 / 心虚血再還流傷害 / 糖質コルチコイド / 肝炎 / 免疫依存性肝炎 / 誘発肝炎 / Con A / 腎間質繊維化 / 動脈硬化 / 内皮前駆細胞 / 臨床心血管病態学 / 血小板 / 脳血栓 / 腎線維化 / 循環器疾患 / 循環器系疾患 / 心筋細胞 / アスピリン / 寒冷ストレス / 非ステロイド性抗炎症薬 / 肝機能障害 / 肝再生 / 受容体欠損マウス / 四塩化炭素 / 急性肝機能障害 Less

Elucidation of the role of prostaglandin D2 in non-alcoholic steatohepatitisPrincipal Investigator
- Principal Investigator
  
  Yuhki Koh-ichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Asahikawa Medical College
Elucidation of the role of prostanoids in the development of liver fibrosis
- Principal Investigator
  
  Ushikubi Fumitaka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Asahikawa Medical College
Regulation of cardiac prostanoid synthesis by glucocorticoid and its pathophysiological meaning
- Principal Investigator
  
  USHIKUBI Fumitaka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
The elucidation of the signal transduction system of ischemic myocardial protection of prostanoidsPrincipal Investigator
- Principal Investigator
  
  YUHKI KOH-ICHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
Roles of the prostanoids in the regulation of immunological responses
- Principal Investigator
  
  USHIKUBI Fumitaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
Roles of the prostanoids in the pathogenesis of cardiovascular diseases
- Principal Investigator
  
  USHIKUBI Fumitaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
Role of prostanoids in the bone marrow derived endothelial cells
- Principal Investigator
  
  OKADA Motoi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Asahikawa Medical College
The mechanism elucidation of the protective effect of prostanoids in ischemic myocardial protectionPrincipal Investigator
- Principal Investigator
  
  YUHKI Koh-Ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
Roles of prostanoids in the pathogenesis of cardiovascular diseases
- Principal Investigator
  
  USHIKUBI Fumitaka
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
A study of the roles of prostanoids and its therapeutic application in cardiovascular remodeling
- Principal Investigator
  
  HARA Akiyoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  International University of Health and Welfare
Roles of the prostanoids in the myocardial infarction and application to the treatmentPrincipal Investigator
- Principal Investigator
  
  YUHKI Koh-Ichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Asahikawa Medical College
受容体欠損マウスを用いた虚血-再灌流障害におけるプロスタグランジンE_2の役割解明Principal Investigator
- Principal Investigator
  
  結城幸一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Asahikawa Medical College
A study of roles of the prostanoids in cardiovascular remodeling using mice lacking deficient in prostanoid receptors
- Principal Investigator
  
  HARA Akiyoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Asahikawa Medical College
プロスタノイドの肝機能障害・肝再生におけるプロスタノイドの役割解明
- Principal Investigator
  
  USHIKUBI Fumitaka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Asahikawa Medical College
Roles of prostanoids in cardiovascular system revealed from studies using knockout mice
- Principal Investigator
  
  USHIKUBI Fumitaka
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Asahikawa Medical College
心肥大・心不全における内因性プロスタノイドの役割の解明Principal Investigator
- Principal Investigator
  
  結城幸一
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Asahikawa Medical College
心不全の心筋におけるエンドセリン産生の転写調節機構に関する分子生物学的研究Principal Investigator
- Principal Investigator
  
  結城幸一
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Asahikawa Medical College
  University of Tsukuba

[Book] NSAIDsの使い方コツと落とし穴2006
- Author(s)
  結城幸一
- Publisher
  中山書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] 非アルコール性脂肪肝炎におけるプロスタノイドの役割2018
- Author(s)
  結城幸一、粂井志麻、柏木仁、今道力敬、牛首文隆
- Journal Title
  
  炎症と免疫
  
  Volume: 26 Pages: 24-29
- Data Source
  KAKENHI-PROJECT-18H02576
[Journal Article] 虚血による神経障害の分子メカニズム　プロスタノイドの役割2014
- Author(s)
  小島史章、結城幸一、柏木仁、粂井志麻、牛首文隆
- Journal Title
  
  日本臨牀
  
  Volume: 72
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] Prostacyclin Stimulated Integrin-Dependent Angiogenic Effects of Endothelial Progenitor Cells and Mediated Potent Circulation Recovery in Ischemic Hind Limb Model2013
- Author(s)
  油川陽子、川辺淳一、岡田基　その他
- Journal Title
  
  Circ J
  
  Volume: 77 Issue: 4 Pages: 1053-1062
- DOI
  10.1253/circj.CJ-12-0897
- NAID
  10031139011
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590765, KAKENHI-PROJECT-23590294
[Journal Article] Prostacyclin stimulated integrin-dependent angiogenic effects of endothelial progenitor cells and mediated potent circulation recovery in ischemic hind limb model2013
- Author(s)
  Aburakawa Y, Kawabe J, Okada M,Yamauchi A, Asanome A, Kabara M,Matsuki M, Takehara N, Nakagawa N,Okumura S, Minami Y, Mizukami Y, YuhkiK, Ushikubi F, Hasebe N
- Journal Title
  
  Circ J
  
  Volume: 77(4) Pages: 1053-1062
- NAID
  10031139011
- Data Source
  KAKENHI-PROJECT-22590765
[Journal Article] Prostacyclin stimulated integrin-dependent angiogenic effects of endothelial progenitor cells and mediated potent circulation recovery in ischemic hind limb model2013
- Author(s)
  Aburakawa Y, Yuhki K, Ushikubi F, Hasebe N, et al
- Journal Title
  
  Circ J
  
  Volume: 77 Pages: 1053-1062
- NAID
  10031139011
- Data Source
  KAKENHI-PROJECT-22390045
[Journal Article] Prostacyclin stimulated integrin-dependent angiogenic effects of endothelial progenitor cells and mediated potent circulation recovery in ischemic hind limb model2013
- Author(s)
  Aburakawa Y, Yuhki K, Ushikubi F, Hasebe N, et al
- Journal Title
  
  Circ J
  
  Volume: 77 Pages: 1053-1062
- NAID
  10031139011
- Data Source
  KAKENHI-PROJECT-23659130
[Journal Article] プロスタノイド受容体欠損マウスを用いた心血管系におけるプロスタノイドの作用2012
- Author(s)
  結城幸一、柏木仁、小島史章、牛首文隆
- Journal Title
  
  血栓と循環
  
  Volume: 20 Pages: 4-8
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] 17β-Estradiol is critical for the preovulatory induction of prostaglandin E_2 synthesis in mice2012
- Author(s)
  Toda K, Yuhki K, Ushikubi F, Saibara T, et al
- Journal Title
  
  J Gastroenterol. In press. Mol Cell Endocrinol
  
  Volume: 362 Pages: 176-182
- Data Source
  KAKENHI-PROJECT-22390045
[Journal Article] 17β-Estradiol is critical for the preovulatory induction of prostaglandin E_2 synthesis in mice2012
- Author(s)
  Toda K, Yuhki K, Ushikubi F, Saibara T, et al
- Journal Title
  
  J Gastroenterol. In press. Mol Cell Endocrinol.
  
  Volume: 362 Pages: 176-182
- Data Source
  KAKENHI-PROJECT-23659130
[Journal Article] The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice.2012
- Author(s)
  Nakagawa N, Yuhki K, Kawabe J, Fujino T, Takahata O, Kabara M, Abe K, Kojima F, Kashiwagi H, Hasebe N, Kikuchi K, Sugimoto Y, Narumiya S, Ushikubi F.
- Journal Title
  
  Kidney International
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] The intrinsic prostaglandin E_2-EP_4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice2012
- Author(s)
  Nakagawa N, Yuhki K, Kojima F, Kashiwagi H, Ushikubi F, et al
- Journal Title
  
  T. Kidney Int
  
  Volume: 82 Pages: 158-171
- Data Source
  KAKENHI-PROJECT-23659130
[Journal Article] The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice2012
- Author(s)
  Nakagawa N, Yuhki K, et al.
- Journal Title
  
  Kidney International
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390045
[Journal Article] The intrinsic prostaglandin E_2-EP_4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice2012
- Author(s)
  Nakagawa N, Yuhki K, Kojima F, Kashiwagi H, Ushikubi F, et al
- Volume
  82
- Pages
  158-171
- Data Source
  KAKENHI-PROJECT-22390045
[Journal Article] 牛首文隆PG/LTと炎症2012
- Author(s)
  小島史章, 結城幸一, 柏木仁, 粂井志麻
- Journal Title
  
  日本臨床
  
  Volume: 70巻(suppl.8) Pages: 231-235
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] プロスタノイド受容体欠損マウスを用いた心血管系におけるプロスタノイドの作用2012
- Author(s)
  結城幸一, 柏木仁, 小島史章, 牛首文隆
- Journal Title
  
  血栓と循環
  
  Volume: 20巻 Pages: 4-8
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] 17β-Estradiol is critical for the preovulatory induction of prostaglandin E_2 synthesis in mice2012
- Author(s)
  Toda K, Ono M, Yuhki K, Ushikubi F, Saibara T
- Journal Title
  
  Mol. Cell. Endocrinol
  
  Volume: 362 Pages: 176-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] エイコサノイド2012
- Author(s)
  結城幸一、柏木仁、小島史章、牛首文隆
- Journal Title
  
  臨床検査
  
  Volume: 56 Pages: 145-150
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] エイコサノイド2012
- Author(s)
  結城幸一, 柏木仁, 小島史章, 牛首文隆
- Journal Title
  
  臨床検査
  
  Volume: 56巻 Pages: 145-150
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] PG/LT系と炎症2012
- Author(s)
  小島史章、結城幸一、柏木仁、粂井志麻、牛首文隆
- Journal Title
  
  日本臨床
  
  Volume: 70 Suppl.8 Pages: 231-235
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice.2012
- Author(s)
  Nakagawa N, Yuhki K, Kawabe J, et al.
- Journal Title
  
  Kidney International
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659130
[Journal Article] The intrinsic prostaglandin E_2-EP_4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice2012
- Author(s)
  Nakagawa N, Yuhki K, Kawabe J, Fujino T, Takahata O, et al
- Journal Title
  
  Kidney Int
  
  Volume: 82 Pages: 158-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] 17β-Estradiol is critical for the preovulatory induction of prostaglandin E2 synthesis in mice.2012
- Author(s)
  Toda K, Ono M, Yuhki K, Ushikubi F, and Saibara T.
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 362 Issue: 1-2 Pages: 176-182
- DOI
  10.1016/j.mce.2012.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590294, KAKENHI-PROJECT-23590979, KAKENHI-PROJECT-24590981
[Journal Article] プロスタノイド受容体ノックアウトマウス2011
- Author(s)
  結城幸一, 他
- Journal Title
  
  The Lipid
  
  Volume: 22 Pages: 120-127
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular system: Novel insights from knockout mouse studies2011
- Author(s)
  Yuhki K, Kojima F, Kashiwagi H, Ushikubi F, et al
- Journal Title
  
  Pharmacol Ther
  
  Volume: 129 Pages: 195-205
- Data Source
  KAKENHI-PROJECT-22390045
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases : Novel insights from knockout mouse studies.2011
- Author(s)
  Yuhki K, Kojima F, Kashiwagi H, Kawabe J, Fujino T, Narumiya S, Ushikubi F
- Journal Title
  
  Pharmacol.Ther. 129
  
  Pages: 195-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases : Novel insights from knockout mouse studies.2011
- Author(s)
  Yuhki, K., et al.
- Journal Title
  
  Pharmaology & Therapeutics
  
  Volume: 129 Pages: 195-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular system: Novel insights from knockout mouse studies2011
- Author(s)
  Yuhki K, Kojima F, Kashiwagi H, Ushikubi F, et al
- Journal Title
  
  Pharmacol Ther
  
  Volume: 129 Pages: 195-205
- Data Source
  KAKENHI-PROJECT-23659130
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases: Novel insightsfrom knockout mouse studies2011
- Author(s)
  Yuhki K,Kojima F, Kashiwagi H, Kawabe J, Fujino T
- Journal Title
  
  Narumiya S and Ushikubi F. PharmacoTherap
  
  Volume: 129 Pages: 195-205
- Data Source
  KAKENHI-PROJECT-22590765
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases.2010
- Author(s)
  Yuhki, K., et al.
- Journal Title
  
  Int.Angiol. 29(2 Suppl 1)
  
  Pages: 19-27
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases2010
- Author(s)
  Yuhki, K., Kashiwagi, H., Kojima, F., Kawabe, J., Ushikubi, F.
- Journal Title
  
  Int Angiol. 29(Suppl 2)
  
  Pages: 19-27
- Data Source
  KAKENHI-PROJECT-19390060
[Journal Article] Selective activation of the prostaglandin E_2 receptor subtype EP_2 or EP_4 leads to inhibition of platelet aggregation2010
- Author(s)
  Kuriyama S, Kashiwagi H, Yuhki K, Kojima F, Ushikubi F, et al
- Journal Title
  
  Thromb Haemost
  
  Volume: 104 Pages: 796-803
- Data Source
  KAKENHI-PROJECT-22390045
[Journal Article] Prostaglandin I_2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling2010
- Author(s)
  Kawabe, J., Yuhki, K., Okada, M., Kanno, T., Yamauchi, A., Tashiro, N., Sasaki, T., Okumura, S., Nakagawa, N., Aburakawa, Y., Takehara, N., Fujino, T., Hasebe, N., Narumiya, S., Ushikubi, F.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 30
  
  Pages: 464-470
- Data Source
  KAKENHI-PROJECT-19390060
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases.2010
- Author(s)
  Yuhki K, Kashiwagi H, Kojima F, Kawabe J, Ushikubi F
- Journal Title
  
  Int.Angiol. 29(2 Suppl)
  
  Pages: 19-27
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Selective activation of the prostaglandin E_2 receptor subtype EP_2 or EP_4 leads to inhibition of platelet aggregation.2010
- Author(s)
  Kuriyama S, Kashiwagi H, , Yuhki K, Kojima F, Yamada T, Fujino T, Hara A, Takayama K, Maruyama T, Yoshida A, Narumiya S, Ushikubi F
- Journal Title
  
  Thromb.Haemost. 104
  
  Pages: 796-803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling2010
- Author(s)
  Kawabe J, Yuhki KI,Okada M, Kanno T, Yamauchi A, Tashiro N,Sasaki T, Okumura S, Nakagawa N,Aburakawa Y, Takehara N, Fujino T, HasebeN, Narumiya S, Ushikubi F
- Journal Title
  
  Atheroscler.Thromb Vasc Biol
  
  Volume: 30 Pages: 464-470
- Data Source
  KAKENHI-PROJECT-22590765
[Journal Article] プロスタノイドと循環器疾患2009
- Author(s)
  結城幸一, 他
- Journal Title
  
  The Lipid 20
  
  Pages: 277-283
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Prostaglandin I_2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling2009
- Author(s)
  Kawabe, J., Yuhki, K., et al.
- Journal Title
  
  Arterioscler.Thromb.Vasc.Biol. 30
  
  Pages: 464-470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390060
[Journal Article] プロスタノイドの循環器疾患における役割〜受容体欠損マウスを用いた解析〜2009
- Author(s)
  結城幸一
- Journal Title
  
  生化学 81
  
  Pages: 84-94
- NAID
  10024915785
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] プロスタノイド受容体欠損マウスの解析から明らかになったその病態生理における役割2008
- Author(s)
  結城幸一
- Journal Title
  
  最新医学 63
  
  Pages: 1964-1971
- Data Source
  KAKENHI-PROJECT-20590244
[Journal Article] Prostaglandin I_2 plays a key role in zymosan-induced mouse pleurisy2008
- Author(s)
  Yuhki, K., Ushikubi, F., Naraba, H., Ueno, A., Kato, H., Kojima, F., Narumiya, S., Sugimoto, Y., Matsushita, M., Oh-ishi, S.
- Journal Title
  
  J Pharmacol Exp Ther. 325
  
  Pages: 601-609
- Data Source
  KAKENHI-PROJECT-19390060
[Journal Article] Prostaglandin I_2 plays a key role in zymosan-induced mouse pleurisy.2008
- Author(s)
  Yuhki K
- Journal Title
  
  J. Pharmacol. Exp. Ther. 325
  
  Pages: 601-609
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] Prostaglandin I_2 plays a key role inzymosan-induced mouse pleurisy.2008
- Author(s)
  Yuhki, K.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 325
  
  Pages: 601-609
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] The role of the prostanoids in inflammatory tachycardia.2006
- Author(s)
  Yuhki K
- Journal Title
  
  Am. J. Physiol. 290
  
  Pages: 1751-1751
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] The role of the prostanoids in inflammatory tachycardia.2006
- Author(s)
  Yuhki, K
- Journal Title
  
  American Journal of Physiology 290
  
  Pages: 1751-1751
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] Fat, keeping the heart healthy?2005
- Author(s)
  Yuhki, K.
- Journal Title
  
  Nature Medicine 325
  
  Pages: 1048-1049
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] Fat, keeping the heart healthy?2005
- Author(s)
  Yuhki, K
- Journal Title
  
  Nature Medicine 11・10
  
  Pages: 1048-1049
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] Fat, keeping the heart healthy?2005
- Author(s)
  Yuhki K
- Journal Title
  
  Nat. Med. 11
  
  Pages: 1048-1049
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] Prostaglandin E_2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP_42004
- Author(s)
  Xiao, C.-Y., Yuhki, K.et al.
- Journal Title
  
  Circulation 109
  
  Pages: 2462-2468
- Data Source
  KAKENHI-PROJECT-14370049
[Journal Article] Prostaglandin receptors, EP2,EP3 and IP, mediate exudate formation in carrageenin-induced mouse pleurisy.2004
- Author(s)
  Yuhki, K
- Journal Title
  
  J.Pharmacol.Exp.Ther. 311
  
  Pages: 1218-1224
- Data Source
  KAKENHI-PROJECT-15790374
[Journal Article] Prostaglandin E_2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP_4.2004
- Author(s)
  Xiao, C.-Y., Yuhki, K.et al.
- Journal Title
  
  Circulation 109
  
  Pages: 2462-2468
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370049
[Journal Article] Prostaglandin I_2 plays a key role in zymosan-induced mouse pleurisy.
- Author(s)
  Yuhki, K., et. al.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590211
[Journal Article] 牛首文隆虚血による神経障害の分子メカニズムプロスタノイドの役割
- Author(s)
  小島史章, 結城幸一, 柏木仁, 粂井志麻
- Journal Title
  
  日本臨牀
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23590294
[Journal Article] Selective activation of prostaflandin E_2 receptor subtype EP_2 or EP_4 leads to inhibition of platelet aggregation
- Author(s)
  Kuriyama, S., Kashiwagi, H., Yuhki, K., Kojima, F., Yamada, T., Fujino, T., Hara, A., Takayama, K., Maruyama, T., Yoshida, A., Narumiya, S., Ushikubi F.
- Journal Title
  
  Thromb Haemost. (In press)
- Data Source
  KAKENHI-PROJECT-19390060
[Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases : Novel insights from knockout mouse studies
- Author(s)
  Yuhki, K., Kojima, F., Kashiwagi, H., Kawabe, J., Fujino, T., Narumiya, S., Ushikubi, F.
- Journal Title
  
  Pharmacol Ther. (In press)
- Data Source
  KAKENHI-PROJECT-19390060
[Journal Article] Prostaglandin I_2 plays a key role in zymosan-induced mouse pleurisy
- Author(s)
  Yuhki, K., Ushikubi, F., et. al.
- Journal Title
  
  J. Pharmacol. Exp. Ther. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390060
[Presentation] Roles of prostanoids in hepatic stellate cell function2022
- Author(s)
  結城幸一、大久保知子、中山恒、成宮周、牛首文隆
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07096
[Presentation] マウス肝再生におけるプロスタグランジン I2 と TNF-a の役割2021
- Author(s)
  結城幸一、平田朋浩、今道力敬、柏木仁、中山恒、成宮周、牛首文隆
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07096
[Presentation] マウス肝再生におけるプロスタグランジンI2とTNF-aの役割2021
- Author(s)
  結城幸一、平田朋浩、今道力敬、柏木仁、中山恒、成宮周、牛首文隆
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02576
[Presentation] Thromboxane A_2 plays a critical role in reduction of the anti-platelet effect of prostaglandin I_2 receptor agonist beraprost after repeated administration2014
- Author(s)
  Kashiwagi H, Yuhki K, Kojima F, Kumei S, Sakai Y, Narumiya S, Ushikubi F
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台(発表は21日)
- Data Source
  KAKENHI-PROJECT-23590294
[Presentation] Thromboxane A2 plays a critical role in reduction of the anti-platelet effect of prostaglandin I2 receptor agonist beraprost after repeated administration.2014
- Author(s)
  Kashiwagi H, Yuhki K, Kojima F, Kumei S, Sakai Y, Narumiya S, Ushikubi F.
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590294
[Presentation] シスプラチン誘発急性腎障害におけるプロスタグランジンE2受容体サブタイプEP1の役割2013
- Author(s)
  小島史章、結城幸一、柏木　仁、粂井志麻、成宮周、牛首文隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590294
[Presentation] Inhibition of thromboxane A2 synthase prevents reduction in the anti-platelet effect of a prostaglandin I2 receptor agonist after repeated administration2012
- Author(s)
  Kashiwagi H, Yuhki K, Kojima F, Sakai Y, Narumiya S, and Ushikubi F
- Organizer
  日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590294
[Presentation] 腎間質線維化におけるプロスタグランジンE2-EP4系の役割2011
- Author(s)
  中川直樹、結城幸一、小島史章、柏木仁、藤野貴行、川辺淳一、長谷部直幸、牛首文隆
- Organizer
  日本薬理学会北部会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590294
[Presentation] トロンボキサンA2合成酵素の阻害はプロスタグランジンI2受容体の脱感作を抑制する2011
- Author(s)
  柏木仁、結城幸一、小島史章、酒井芳紀、牛首文隆
- Organizer
  日本薬理学会北部会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590294
[Presentation] プロスタグランジンE2はEP4受容体を介して心臓における後期虚血プレコンディショニングを仲介している2009
- Author(s)
  菅野貴康、川辺淳一、結城幸一、竹原有史、長谷部直幸、牛首文隆
- Organizer
  第60回日本薬理学会北部会
- Place of Presentation
  富山
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20590244
[Presentation] 循環器疾患におけるプロスタノイドの役割2009
- Author(s)
  結城幸一、成宮周、牛首文隆
- Organizer
  第46回日本生化学会北海道支部会
- Place of Presentation
  旭川
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20590244
[Presentation] 循環器疾患におけるプロスタノイドの役割2009
- Author(s)
  結城幸一, 他
- Organizer
  日本生化学会北海道支部第46回例会
- Place of Presentation
  旭川
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20590244
[Presentation] 炎症性頻脈における一酸化窒素の役割2009
- Author(s)
  金井麻子、結城幸一, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590244
[Presentation] The Cardioprotective Effect of Prostaglandin E2/EP4 System is Important for the Late Phase2009
- Author(s)
  Kanno T, Kawabe J, Yuhki K, Takehara N, Ushikubi F, Hasebe N
- Organizer
  Preconditioning American Heart Association Scientific Sessions 2009
- Place of Presentation
  アメリカ/オーランド
- Year and Date
  2009-11-16
- Data Source
  KAKENHI-PROJECT-20590244
[Presentation] プロスタグランジンE_2受容体サブタイプEP_2とEP_4の活性化は血小板凝集を抑制する2009
- Author(s)
  柏木仁、結城幸一, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590244
[Presentation] 血管リモデリング形成に及ぼす内因性プロスタグランジンI_2の役割2008
- Author(s)
  高畑治、結城幸一、他
- Organizer
  日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] プロスタグランジンE_2はその受容体EP_3を介して虚血-再灌流障害から心臓を保護する2007
- Author(s)
  結城幸一、肖春陽、原明義、川辺純一、成宮周、牛首文隆
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2007-03-16
- Data Source
  KAKENHI-PROJECT-18590229
[Presentation] Prostaglandin E_2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP_3-2007
- Author(s)
  結城幸一
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] Prostaglandin E_2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP_3.2007
- Author(s)
  Yuhki K
- Organizer
  80th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Nagoya.
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] Key rols of complement activation and prostaglandin I_2 for exudate formation in zymosan-induced mouse pleurisy.2006
- Author(s)
  Yuhki K
- Organizer
  79th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Yokohama.
- Year and Date
  2006-03-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] Roles of the prostanoids in the cardiovascular system.2006
- Author(s)
  Yuhki K
- Organizer
  79th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Yokohama.
- Year and Date
  2006-03-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] Roles of the prostanoids in the cardiovascular system.2006
- Author(s)
  結城幸一
- Organizer
  第79回日本薬理学会年会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2006-03-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] Key roles of complement activation and prostaglandin I_2 for exudate formation inzymosan-induced mouse pleurisy.2006
- Author(s)
  結城幸一
- Organizer
  第79回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2006-03-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] The prostaglandin E_2-EP_4 system protects the heart from ischemia-reperfusion injury.2005
- Author(s)
  Yuhki K
- Organizer
  12TH WORLD CONGRESS ON HEART DISEASE
- Place of Presentation
  Canada.
- Year and Date
  2005-07-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590211
[Presentation] The prostaglandin E_2-EP_4 system protects the heart from ischemia-reperfusion injury.2005
- Author(s)
  Yuhki, K
- Organizer
  12TH WORLD CONGRESS ON HEART DISEASE-NEW TRENDS IN RESEARCH, DIAGNOSIS AND TREATMENT
- Place of Presentation
  Canada
- Year and Date
  2005-07-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590211

1. USHIKUBI Fumitaka (50243035)

# of Collaborated Projects: 8 results

# of Collaborated Products: 18 results
2. KASHIWAGI Hitoshi (60510609)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
3. HARA Akiyoshi (90164988)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. KOJIMA Fumiaki (30550545)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 藤野貴行 (70322914)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 今道力敬 (00570194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. SUZUKI Yasuhiro (80451459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKADA Motoi (80431427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KAWABE Junichi (10400087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. HANAKAI Takahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KONDO Yuhki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YANAGISAWA Terufumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YUHKI koh-ichi 結城 幸一

Yuhki Koh-ichi 結城 幸一

YUHKI Koh-ichi 結城 幸一

Research Projects

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Co-Researchers

Elucidation of the role of prostaglandin D2 in non-alcoholic steatohepatitisPrincipal Investigator

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The elucidation of the signal transduction system of ischemic myocardial protection of prostanoidsPrincipal Investigator

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The mechanism elucidation of the protective effect of prostanoids in ischemic myocardial protectionPrincipal Investigator

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Roles of the prostanoids in the myocardial infarction and application to the treatmentPrincipal Investigator

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受容体欠損マウスを用いた虚血-再灌流障害におけるプロスタグランジンE_2の役割解明Principal Investigator

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YUHKI koh-ichi 結城幸一

Yuhki Koh-ichi 結城幸一

YUHKI Koh-ichi 結城幸一

[Book] NSAIDsの使い方コツと落とし穴2006

[Journal Article] 虚血による神経障害の分子メカニズム　プロスタノイドの役割2014