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Hara Akiyoshi
原 明義
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Alternative Names
HARA Akiyoshi 原 明義
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Researcher Number
90164988
Other IDs
External Links
Affiliation (Current)
2022: 東北医科薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information)
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2006 – 2008: 国際医療福祉大学, 薬学部, 教授
1999 – 2005: 旭川医科大学, 医学部, 助教授
1994 – 1996: 旭川医科大学, 医学部, 助手
1994: Asahikawa Medical College, School of Medicine, Assistant, 医学部・薬理学講座, 助手
Review Section/Research Field
Principal Investigator
General pharmacology
/
General pharmacology
/
Pathological medical chemistry
Except Principal Investigator
General pharmacology
/
Pathological medical chemistry
Keywords
Principal Investigator
心機能 / エネルギー代謝 / アデノシン / 心臓 / ラット / ジラゼップ / プロスタノイド / 心筋リモデリング / 心肥大 / マウス
…
More
/ プロスタグランジンI_2 / 低酸素 / ATP感受性Kチャネル / Hydrogen peroxide / フリーラジカル / 脂質過酸化 / 長鎖アシルカルニチン / K-7259 / 非ステロイド性抗炎症薬 / 寒冷ストレス / アスピリン / 心筋細胞 / 受容体 / 線維化 / プロスタグランジン I_2 / prostanoids / prostaglandin I_2 / prostanoid receptors / cardiac hypertrophy / cardiac fibrosis / cardiac remodeling / mice
…
More
Except Principal Investigator
プロスタノイド / プロスタグランジン / トロンボキサン / 虚血・再潅流 / prostaglandin / 活性酸素 / dilazep / 虚血・再潅流障害 / 心筋 / ノックアウトマウス / プロスタノイド受容体 / 血小板 / prostanoids / thromboxane / knockout mice / prostanoid receptor / platelets / 過酸化水素 / 細胞内Ca^<2+>濃度 / lysophosphatidylcholine / d-propranolol / ラット心室筋細胞 / [Ca^<2+>]_<in> / veratridine / Na^+チャネル / propranolol / リドカイン / OXYGEN RADICAL / HYDROGEN PEROXIDE / INTRACELLULAR CALCIUM / LYSOPHOPHATIDYLCHOLINE / d-PROPRANOLOL / DILAZEP / リゾホスファチジルコリン / パルミトイル-L-カルニチン / 一酸化窒素 / 虚血-再潅流障害 / 心筋保護 / K-7259 / NO / ラット / 摘出心臓 / L-NAME / Myocardium / ischemia / reperfusion damage / oxygen radicals / Lysophosphatidylcholine / Palmitoylcarnitin / Nitric oxide / 循環器系 / 循環器 / 心筋虚血 / 心肥大 / cardiovascular system / ischemia-reperfusion / 受精 / アレルギー性喘息 / 中枢神経機能 / 肺高血圧症 / 気管支喘息 / 大腸癌 / fertilization / allergic asthma / ischemia-reperfusipn / 心臓 / 血管 / prostanoid
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Research Projects
(
10
results)
Research Products
(
5
results)
Co-Researchers
(
11
People)
Project Start Year (Newest)
Project Start Year (Oldest)
A study of the roles of prostanoids and its therapeutic application in cardiovascular remodeling
Principal Investigator
Principal Investigator
HARA Akiyoshi
Project Period (FY)
2006 – 2008
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General pharmacology
Research Institution
International University of Health and Welfare
A study of roles of the prostanoids in cardiovascular remodeling using mice lacking deficient in prostanoid receptors
Principal Investigator
Principal Investigator
HARA Akiyoshi
Project Period (FY)
2003 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Asahikawa Medical College
Roles of prostanoids in cardiovascular system revealed from studies using knockout mice
Principal Investigator
USHIKUBI Fumitaka
Project Period (FY)
2002 – 2004
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Asahikawa Medical College
Roles of prostanoids in cardiovascularsystem revealed from studies using knockout mice
Principal Investigator
USHIKUBI Fumitaka
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General pharmacology
Research Institution
Asahikawa Medical College
Physiological and Pathophysiological roles of prostanoids revealed from studies using mice lacking their receptors
Principal Investigator
USHIKUBI Fumitaka
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General pharmacology
Research Institution
Asahikawa Medical College
長鎖アシルカルニチンによる心筋障害とその防御に関する薬理学的研究
Principal Investigator
Principal Investigator
原 明義
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General pharmacology
Research Institution
Asahikawa Medical College
フリーラジカルによる心筋障害を防御する薬物とその作用機構に関する研究
Principal Investigator
Principal Investigator
原 明義
Project Period (FY)
1995
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
General pharmacology
Research Institution
Asahikawa Medical College
The role of nitric oxide in ischemia/reperfusion damage in the heart
Principal Investigator
ABIKO Yasushi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General pharmacology
Research Institution
Asahikawa Medical College
フリーラジカルによる心筋障害に対する生体内防御機構の解明
Principal Investigator
Principal Investigator
原 明義
Project Period (FY)
1994
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
General pharmacology
Research Institution
Asahikawa Medical College
Pharmacological study on the derangements of myocardial cells induced by oxygen radicals, and protection from the derangements
Principal Investigator
ABIKO Yasushi
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General pharmacology
Research Institution
Asahikawa Medical College
All
2009
2007
2005
All
Journal Article
Presentation
[Journal Article] Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I_2 receptor
2005
Author(s)
Akiyoshi Hara
Journal Title
Circulation 112・1
Pages
: 84-92
Data Source
KAKENHI-PROJECT-15590265
[Journal Article] Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor
2005
Author(s)
Akiyoshi Hara
Journal Title
Circulation 112・1
Pages
: 84-92
Description
「研究成果報告書概要(和文)」より
Data Source
KAKENHI-PROJECT-15590265
[Presentation] 寒冷ストレスによる心肥大形成に対するアスピリンの作用
2009
Author(s)
原 明義, 花開孝宏, 近藤祐樹, 柳沢照史
Organizer
日本薬学会第129年会
Place of Presentation
国立京都国際会館(京都)
Year and Date
2009-03-28
Data Source
KAKENHI-PROJECT-18590229
[Presentation] 寒冷ストレスによる心肥大形成に対するアスピリンの作用
2009
Author(s)
原 明義、花開 孝宏、近藤 祐樹、柳沢 照史
Organizer
日本薬学会第129年会
Place of Presentation
国立京都国際会館(京都市)
Year and Date
2009-03-28
Data Source
KAKENHI-PROJECT-18590229
[Presentation] プロスタグランジンE_2はその受容体EP_3を介して虚血-再灌流障害から心臓を保護する
2007
Author(s)
結城幸一、肖 春陽、原 明義、川辺純一、成宮 周、牛首文隆
Place of Presentation
名古屋国際会議場(名古屋市)
Year and Date
2007-03-16
Data Source
KAKENHI-PROJECT-18590229
# of Projects (Dsc)
# of Projects (Asc)
1.
YUHKI Koh-ichi
(80302420)
# of Collaborated Projects:
4 results
# of Collaborated Products:
2 results
2.
USHIKUBI Fumitaka
(50243035)
# of Collaborated Projects:
4 results
# of Collaborated Products:
1 results
3.
ABIKO Yasushi
(90041821)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
4.
HASHIZUME Hiroko
(00154021)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
藤野 貴行
(70322914)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
YAZAWA Kazuto
(90212274)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
KOBAYASHI Takuya
(20311730)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
BITO Haruhiko
(00291964)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
HANAKAI Takahiro
# of Collaborated Projects:
1 results
# of Collaborated Products:
2 results
10.
KONDO Yuhki
# of Collaborated Projects:
1 results
# of Collaborated Products:
2 results
11.
YANAGISAWA Terufumi
# of Collaborated Projects:
1 results
# of Collaborated Products:
2 results
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