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Watanabe Naoki  渡邊 直樹

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WATANABE Naoki  渡邊 直樹

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Researcher Number 80303816
Other IDs
External Links
Affiliation (Current) 2025: 京都大学, 生命科学研究科, 教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 京都大学, 生命科学研究科, 教授
2011: Tohoku University, 生命科学研究科, 教授
2010: 東北大学, 大学院・生命科学研究科, 教授
2007 – 2009: Kyoto University, 医学研究科, 准教授
2003 – 2006: 京都大学, 医学研究科, 助教授
Review Section/Research Field
Principal Investigator
Biological Sciences / General medical chemistry / Medium-sized Section 50:Oncology and related fields / Medium-sized Section 48:Biomedical structure and function and related fields / Cell biology
Except Principal Investigator
Orthopaedic surgery / Cerebral neurosurgery
Keywords
Principal Investigator
アクチン重合 / 細胞シグナル / 生体分子 / 一分子計測 / 細胞・組織 / フォルミンファミリー / ナノバイオ / Rho / mDia1 / mDia … More / Formin / 超解像顕微鏡 / キナーゼ阻害薬 / processive capping / actin polymerization / single-molecule imaging / 単分子イメージング / mDial / 恒常性 / アクチン線維切断 / G蛋白質 / 細胞運動 / 分子モーター / 葉状仮足 / 細胞伸展 / ミオシン / 抗体改変技術 / アクチンオリゴマー / 分子アンフォールディング / 多重細胞マーカー検出 / 細胞分子イメージング / 逆説的活性化 / アロステリック効果 / 物理ストレス / アクチン / 接着斑 / 力覚センサー / Src / 分子標的薬 / アクチン重合センサー / 蛍光単分子イメージング / ブラウンラチェット仮説 / アクチン流動 / 細胞接着 / アロステリック作用 / 逆説的標的分子活性化 / がん治療キナーゼ阻害薬 / 超解像可視化用プローブ / 動的不安定性 / ブラウンラチェット / メカノトランスダクション / globular actin / homeostasis / formin family / 単量体アクチン / プロセッシブキャップ / フォルミン蛋白質 / profilin / molecular motor / Formin family / スペックル顕微鏡 / モーター分子 / 1分子イメージング / プロセッシブキャッピング / プロフィリン / 分子モニター / Forminファミリー / コフィリン / 組織 / 細胞 / Rhoファミリー / キャッピングプロテイン / クラッチモデル / 癌細胞浸潤 / レトログレードフロー / 3複合体 / ARP2 / アクチン求心性流動 … More
Except Principal Investigator
細胞内骨格 / ケモカイン / 成長軟骨 / 骨折 / mDial / Rho / 浸潤 / SDF-1α / 接着班 / 神経膠芽腫 / mDia1 / Rbo Less
  • Research Projects

    (13 results)
  • Research Products

    (223 results)
  • Co-Researchers

    (10 People)
  •  分子・構造変換のリアルタイム可視化からの病気の解明と治療戦略Principal Investigator

    • Principal Investigator
      渡邊 直樹
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Kyoto University
  •  Elucidation of mechanotransduction mechanisms with visualization of moleculesPrincipal Investigator

    • Principal Investigator
      Watanabe Naoki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Kyoto University
  •  アクチン単量体-線維のホメオスターシスを司る細胞シグナルによる物理ストレス応答Principal Investigator

    • Principal Investigator
      渡邊 直樹
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
      Kyoto University
  •  Elucidation of acute actin polymerization signaling using single molecule imaging of filament end factorsPrincipal Investigator

    • Principal Investigator
      WATANABE Naoki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  SDF-1 plays a role in bone growth and repair by cytoskeleton modulation

    • Principal Investigator
      ITO Hiromu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto University
  •  癌細胞浸潤の細胞伸展縁アクチンの求心性流動変化による制御Principal Investigator

    • Principal Investigator
      渡邊 直樹
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  アクチン重合端振動の細胞内可視化Principal Investigator

    • Principal Investigator
      渡邊 直樹
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Single-molecule imaging analysis of cell structural reorganization processes downstream of G protein signalingPrincipal Investigator

    • Principal Investigator
      WATANABE Naoki
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Actin-polymerization-driven molecular dynamics of Formin homology proteins in live cellsPrincipal Investigator

    • Principal Investigator
      WATANABE Naoki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  癌細胞浸潤における細胞内アクチンの求心性流動の役割Principal Investigator

    • Principal Investigator
      渡邊 直樹
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  悪性神経膠芽腫におけるRho情報伝達系による浸潤機構の解析と創薬の探索

    • Principal Investigator
      橋本 信夫
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kyoto University
  •  癌細胞浸潤における細胞内アクチンの求心性流動の役割Principal Investigator

    • Principal Investigator
      渡邊 直樹
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Identification of intracellular signaling cascade of Rho and mDia1 based on high sensitivity live-cell imagingPrincipal Investigator

    • Principal Investigator
      WATANABE Naoki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Kyoto University

All 2023 2022 2021 2020 2019 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] Plasma Membrane Shaping "Brownian ratchet force sensor at the contacting point between F-actin barbed end and lamellipodium tip plasma membrane"2022

    • Author(s)
      Naoki Watanabe
    • Publisher
      Elsevir
    • ISBN
      9780323899116
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Book] 決定版 阻害剤・活性化剤ハンドブック 「アクチン細胞骨格系阻害薬」の項2019

    • Author(s)
      渡邊 直樹、清末 優子(秋山 徹、河府 和義 編)
    • Total Pages
      648
    • Publisher
      羊土社
    • ISBN
      9784758120999
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Book] ライフサイエンス新着論文レビューhttp://first.lifesciencedb.jp/archives/18962011

    • Author(s)
      渡邊直樹, 水野裕昭
    • Publisher
      アクチン線維の二重らせん鎖にそったフォルミンmDia1の回転運動
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Book] A possible role of homeostasis between monomeric and filamentous actin in filament nucleation revealed by pharmacokinetic modeling. Systems Biology The Challenge of Complexity2009

    • Author(s)
      Watanabe, N., Higashida, C.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] Systems Biology The Challenge of Complexity. Chapter : "A possible role of homeostasis between monomeric and filamentous actin in filament nucleation reveald by pharmacokinetic modeling."2009

    • Author(s)
      Watanabe. N., Higashida, C.
    • Total Pages
      7
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] Nat. Cell Biol. 11(Migration without a clutch.)2009

    • Author(s)
      Narumiya, S., Watanabe, N.
    • Publisher
      News and Views
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] Systems Biology The Challenge of Complexity. Chapter : "A possible role of homeostasis between monomeric and filamentous actin in filament nucleation reveald by pharmacokinetic modeling."2009

    • Author(s)
      Watanabe N. and Higashida C.
    • Total Pages
      7
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] Systems Biology The Challenge of Complexity. Chapter : "A possible role of homeostasis between monomeric and filamentous actin in filament nucleation reveald by pharmacokinetic modeling. "2009

    • Author(s)
      Watanabe N., Higashida C.
    • Total Pages
      7
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Book] Systems Biology The Challenge of Complexity. Chapter : "A possible role of homeostasis between monomeric and filamentous actin in filament nucleation reveald by pharmacokinetic modeling."2009

    • Author(s)
      Watanabe N., Higashida C.
    • Total Pages
      7
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Book] A possible role of homeostasis between monomeric and filamentous actin in filament nucleation reveald by pharmacokinetic modeling2008

    • Author(s)
      Watanabe N. and Higashida C.
    • Publisher
      Systems Biology The Challenge of Complexity. Springer
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Book] アクチン重合システムを解く分子イメージング:みえない脱重合反応をとらえる分子細胞治療2007

    • Author(s)
      渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 非侵襲・可視化技術ハンドブック-ナノ・バイオ・医療から情報システムまで-(共著)第8章第10節 アクチン細胞骨格のダイナミクスの可視化2007

    • Author(s)
      渡邊 直樹(小川誠二, 上野照剛編)
    • Total Pages
      81080
    • Publisher
      エヌ・ティー・エス出版
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] アクチン細胞骨格のダイナミクスの可視化非侵襲・可視化技術ハンドブック-ナノ・バイオ・医療から情報システムまで-2007

    • Author(s)
      渡邊直樹
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 非侵襲・可視化技術ハンドブックーナノ・バイオ・医療から情報システムまで-(共著)第8章第10節 アクチン細胞骨格のダイナミクスの可視化2007

    • Author(s)
      渡邊 直樹(小川誠二, 上野照剛編)
    • Total Pages
      8
    • Publisher
      エヌ・ティー・エス出版
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Book] 生理活性物質のケミカルバイオロジーを開拓した論文(Mayer, T.U. et. al. )2007

    • Author(s)
      木下専, 渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 単分子イメージングが明らかにした生細胞内アクチン重合機構日本臨床2007

    • Author(s)
      辻貴宏, 渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] アクチンダイナミクス蛋白質核酸酵素2006

    • Author(s)
      渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 単分子スペックル顕微鏡によるアクチンダイナミックス観察実 験医学2006

    • Author(s)
      渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] アクチン細胞骨格とアクチン調節タンパク質実験医学第24巻第13号増刊形と運動を司る細胞のダイナミクス2006

    • Author(s)
      馬渕一誠, 渡邊直樹, 寺崎朝子, 高稲正勝, 斧正一郎
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 細胞の中を分子でのぞく-Less is moreとSerendipity-学術月報2005

    • Author(s)
      渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] アクチン重合が駆動する細胞運動の謎に挑む単分子イメージング生物物理2005

    • Author(s)
      渡邊直樹, 東田知陽, 三好拓志
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] Forminファミリー2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] mDia1とForminファミリー:アクチン伸長端をサーフィンするプロセッシブキャッパー生化学2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 単分子スペックル顕微鏡がみせるアクチン重合の細胞内分子キネティクス日本薬理学雑誌2005

    • Author(s)
      渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 単分子スペックル顕微鏡によるアクチン生化学の一分子イメージング蛋白質核酸酵素2005

    • Author(s)
      東田知陽, 三好拓志, 渡邊直樹
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Book] 単分子スペックル顕微鏡法によるアクチン重合ダイナミクス解析 わかる実験医学シリーズ 細胞骨格・運動がわかる2004

    • Author(s)
      渡邊直樹, 東田知陽
    • Total Pages
      5
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] Brownian Ratchet-based Force Sensor, Lamellipodium2023

    • Author(s)
      WATANABE Naoki
    • Journal Title

      Seibutsu Butsuri

      Volume: 63 Issue: 3 Pages: 143-147

    • DOI

      10.2142/biophys.63.143

    • ISSN
      0582-4052, 1347-4219
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Journal Article] 多重高密度超解像顕微鏡IRISによる多分子複合体マッピングの病理診断への応用2023

    • Author(s)
      宮本章歳、渡邊直樹
    • Journal Title

      Precision Medicine

      Volume: 6 Pages: 33-37

    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Journal Article] Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin2023

    • Author(s)
      Yamashiro Sawako、Rutkowski David M.、Lynch Kelli Ann、Liu Ying、Vavylonis Dimitrios、Watanabe Naoki
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 8468-8468

    • DOI

      10.1038/s41467-023-44018-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06150, KAKENHI-PUBLICLY-22H04843, KAKENHI-PUBLICLY-23H04310, KAKENHI-PROJECT-22H00456
  • [Journal Article] 超解像顕微鏡用の迅速解離抗体断片の作製法2023

    • Author(s)
      張千里; 宮本章歳; 渡邊直樹
    • Journal Title

      STAR Protocols

      Volume: 4 Issue: 3 Pages: 102523-102523

    • DOI

      10.1016/j.xpro.2023.102523

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05963, KAKENHI-PROJECT-22H00456
  • [Journal Article] 特集 がん遺伝子の発見は現代医療を進歩させたか Ⅰ.がん遺伝子研究の新しい展開 阻害薬による標的キナーゼの構造的活性化とがん増殖シグナルの誘発2023

    • Author(s)
      渡邊 直樹
    • Journal Title

      生体の科学

      Volume: 74 Issue: 4 Pages: 332-335

    • DOI

      10.11477/mf.2425201703

    • ISSN
      0370-9531, 1883-5503
    • Year and Date
      2023-08-15
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Journal Article] ブラウンラチェットを介する力の受容器ラメリポディア2023

    • Author(s)
      渡邊直樹
    • Journal Title

      生物物理

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Journal Article] Brownian ratchet force sensor at the contacting point between F-actin barbed end and lamellipodium tip plasma membrane2023

    • Author(s)
      Watanabe Naoki
    • Journal Title

      Plasma Membrane Shaping (Elsevier)

      Volume: ー Pages: 295-306

    • DOI

      10.1016/b978-0-323-89911-6.00015-7

    • ISBN
      9780323899116
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Journal Article] ミオシン張力によるアクチン線維安定化の細胞内蛍光単分子イメージング解析2022

    • Author(s)
      山城佐和子、渡邊直樹
    • Journal Title

      BIO Clinica

      Volume: 37 Pages: 1062-1066

    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Journal Article] A mechanism with severing near barbed ends and annealing explains structure and dynamics of dendritic actin networks2022

    • Author(s)
      Holz Danielle、Hall Aaron R、Usukura Eiji、Yamashiro Sawako、Watanabe Naoki、Vavylonis Dimitrios
    • Journal Title

      eLife

      Volume: 11

    • DOI

      10.7554/elife.69031

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06150, KAKENHI-PUBLICLY-21H05780, KAKENHI-PROJECT-22H00456, KAKENHI-PUBLICLY-22H04843, KAKENHI-ORGANIZER-19H05794
  • [Journal Article] Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy2022

    • Author(s)
      Qianli Zhang, Akitoshi Miyamoto, Shin Watanabe, Takao Arimori, Masanori Sakai, Madoka Tomisaki, Tai Kiuchi, Junichi Takagi, Naoki Watanabe
    • Journal Title

      Cell Reports Methods

      Volume: 2 Issue: 10 Pages: 100301-100301

    • DOI

      10.1016/j.crmeth.2022.100301

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06168, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-22H00456, KAKENHI-PROJECT-23K21290
  • [Journal Article] 細胞内蛍光単分子イメージングによるミオシン張力依存的なアクチン線維安定化の証明2021

    • Author(s)
      山城佐和子、渡邊直樹
    • Journal Title

      生体の科学

      Volume: 72

    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Journal Article] A mechanism with severing near barbed ends and annealing explains structure and dynamics of dendritic actin networks2021

    • Author(s)
      Holz Danielle、Hall Aaron R.、Usukura Eiji、Yamashiro Sawako、Watanabe Naoki、Vavylonis Dimitrios
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2021.03.31.437985

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Journal Article] Fast-dissociating but highly specific antibodies are novel tools in biology, especially useful for multiplex super-resolution microscopy2021

    • Author(s)
      Miyoshi Takushi, Friedman Thomas B., Watanabe Naoki
    • Journal Title

      STAR Protocols

      Volume: 2 Issue: 4 Pages: 100967-100967

    • DOI

      10.1016/j.xpro.2021.100967

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Journal Article] Paradoxical activation of c-Src as a drug-resistant mechanism2021

    • Author(s)
      Higuchi Makio、Ishiyama Kenichi、Maruoka Masahiro、Kanamori Ryosuke、Takaori-Kondo Akifumi、Watanabe Naoki
    • Journal Title

      Cell Reports

      Volume: 34 Issue: 12 Pages: 108876-108876

    • DOI

      10.1016/j.celrep.2021.108876

    • NAID

      120006997013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Journal Article] Semi-automated single-molecule microscopy screening of fast-dissociating specific antibodies directly from hybridoma cultures2021

    • Author(s)
      Miyoshi Takushi、Zhang Qianli、Miyake Takafumi、Watanabe Shin、Ohnishi Hiroe、Chen Jiji、Vishwasrao Harshad D.、Chakraborty Oisorjo、Belyantseva Inna A.、Perrin Benjamin J.、Shroff Hari、Friedman Thomas B.、Omori Koichi、Watanabe Naoki
    • Journal Title

      Cell Reports

      Volume: 34 Issue: 5 Pages: 108708-108708

    • DOI

      10.1016/j.celrep.2021.108708

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Journal Article] mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse.2020

    • Author(s)
      Thumkeo, D., Katsura, Y., Nishimura, Y., Kanchanawong, P., Tohyama, K., Ishizaki, T., Kitajima, S., Takahashi, C., Hirata, T., Watanabe, N., Krummel, M. F., and Narumiya, S.
    • Journal Title

      Sci. Adv.

      Volume: 6 Issue: 1 Pages: 2432-2432

    • DOI

      10.1126/sciadv.aay2432

    • NAID

      120006777011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07621, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17K08339, KAKENHI-PROJECT-17K08591, KAKENHI-PROJECT-19H01020, KAKENHI-PROJECT-20H03509
  • [Journal Article] Quantitative high-precision imaging of myosin-dependent filamentous actin dynamics.2020

    • Author(s)
      Yamashiro Sawako, Watanabe Naoki
    • Journal Title

      Journal of Muscle Research and Cell Motility

      Volume: 41 Issue: 1 Pages: 163-173

    • DOI

      10.1007/s10974-019-09541-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06217, KAKENHI-PROJECT-19H01020
  • [Journal Article] Single-molecule visualization of mechanotransduction though actin network systems2020

    • Author(s)
      渡邊 直樹、山城 佐和子
    • Journal Title

      生化学

      Volume: 92 Issue: 1 Pages: 84-93

    • DOI

      10.14952/SEIKAGAKU.2020.920084

    • NAID

      40022176132

    • ISSN
      0037-1017
    • Year and Date
      2020-02-25
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Journal Article] 蛍光単分子イメージングが解き明かすミオシン張力によるアクチン線維安定化2019

    • Author(s)
      山城 佐和子、渡邊 直樹
    • Journal Title

      メディカル・サイエンス・ダイジェスト

      Volume: 45 Pages: 434-437

    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Journal Article] RECK in Neural Precursor Cells Plays a Critical Role in Mouse Forebrain Angiogenesis2019

    • Author(s)
      Li Huiping、Miki Takao、Almeida Glicia Maria de、Hanashima Carina、Matsuzaki Tomoko、Kuo Calvin J.、Watanabe Naoki、Noda Makoto
    • Journal Title

      iScience

      Volume: 19 Pages: 559-571

    • DOI

      10.1016/j.isci.2019.08.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07675, KAKENHI-PLANNED-16H06483, KAKENHI-PROJECT-19H03237, KAKENHI-PROJECT-19H01020
  • [Journal Article] Lamellipodium tip actin barbed ends serve as a force sensor2019

    • Author(s)
      Koseki Kazuma、Taniguchi Daisuke、Yamashiro Sawako、Mizuno Hiroaki、Vavylonis Dimitrios、Watanabe Naoki
    • Journal Title

      Genes to Cells

      Volume: 24 Issue: 11 Pages: 705-718

    • DOI

      10.1111/gtc.12720

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06217, KAKENHI-PROJECT-19H01020
  • [Journal Article] Rotational movement of the formin mDia1 along the double helical strand of an actin filament2011

    • Author(s)
      Mizuno, H., Higashida, C, Yuan, Y., Ishizaki, T., Narumiya, S., Watanabe, N.
    • Journal Title

      Science

      Volume: 331 Pages: 80-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Journal Article] Inside view of cell locomotion through single-molecule : fast F-/G-actin cycle and G-actin regulation of polymer restoration2010

    • Author(s)
      Watanabe, N.
    • Journal Title

      Proc.Jpn.Acad.B.Phys.Biol.Sci.

      Volume: 86 Pages: 62-83

    • NAID

      130000149634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Journal Article] Inside view of cell locomotion through single-molecule : fast F-/G-actin cycle and G-actin regulation of polymer restoration.2010

    • Author(s)
      Watanabe, N.
    • Journal Title

      Proc. Jpn. Acad. B. Phys. Biol. Sci. 86

      Pages: 62-83

    • NAID

      130000149634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Inside view of cell locomotion through single-molecule: fast F-/G-actin cycle and G-actin regulation of polymer restoration.2010

    • Author(s)
      Watanabe, N.
    • Journal Title

      Proc. Jpn. Acad. B. Phys. Biol. Sci. 86

      Pages: 62-83

    • NAID

      130000149634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Inside view of cell locomotion through single-molecule : fast F-/G-actin cycle and G-actin regulation of polymer restoration2010

    • Author(s)
      Watanabe, N.
    • Journal Title

      Proc.Jpn.Acad.B.Phys.Biol.Sci. 86

      Pages: 62-83

    • NAID

      130000149634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Journal Article] Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during PDGF-dependent chemotaxis.2009

    • Author(s)
      Monypenny, J., Zicha, D., Higashida, C, Oceguera-Yanez, F., Narumiya, S., Watanabe, N
    • Journal Title

      Molecular and Cellular Biology

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during PDGF-dependent chemotaxis.2009

    • Author(s)
      Monypenny, J., Zicha, D., Higashida, C., Oceguera-Yanez, F., Narumiya, S., Watanabe, N.
    • Journal Title

      Mol. Cell. Biol. 29

      Pages: 2730-2747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase : requirements of myristoylation and srchomology 3 domain.2009

    • Author(s)
      Fujita, A., Shishido, T., Yuan, Y., Inamoto, E., Narumiya, S., Watanabe. N.
    • Journal Title

      Molecular Pharmacology 75

      Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase : requirements of myristoylation and src homology 3 domain.2009

    • Author(s)
      Fujita, A., Shishido, T., Yuan, Y.Inamoto, E., Narumiya, S., Watanabe, N.
    • Journal Title

      Molecular Pharmacolgy 75

      Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase: requirements of myristoylation and src homology 3 domain.2009

    • Author(s)
      Fujita, A., Shishido, T., Yuan, Y., Inamoto, E., Narumiya, S., Watanabe, N.
    • Journal Title

      Mol. Pharmacol 75

      Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during PDGF-dependent chemotaxis2009

    • Author(s)
      Monypenny, J., Zicha, D., Higashida, C., Oceguera-Yanez, F., Narumiya, S. and Watanabe, N.
    • Journal Title

      Molecular and Cellular Biology

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] An order of magnitude faster AIPl-associated actin disruption than nucleation by the Arp2/3 complex in lamellipodia.2009

    • Author(s)
      Tsuji, T., Miyoshi, T., Higashida, C, Narumiya, S., Watanabe, N.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] An order of magnitude faster AIP1 associated actin disruption than nucleation by the Arp2/3 complex in lamellipodia2009

    • Author(s)
      Tsuji, T., Miyoshi, T., Higashida, C.,Narumiya, S. Watanabe, N.
    • Journal Title

      PLoS ONE 4

    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] An order of magnitude faster AIP1-associated actin disruption than nucleation by the Arp2/3 complex in lamellipodia.2009

    • Author(s)
      Tsuji, T., Miyoshi, T., Higashida, C., Narumiva, S. and Watanabe, N.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] An order of magnitude faster AIP1-associated actin disruption than nucleation by the Arp2/3 complex in lamellipodia.2009

    • Author(s)
      Tsuji, T., Miyoshi, T., Higashida, C., Narumiya, S., Watanabe, N.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Imatinib mesylate (STI571)-induced cell edge translocation of kinase active and kinase defective Abelson kinase : requirements of myristoylation and src homology 3 domain2009

    • Author(s)
      Fujita, A., Shishido, T., Yuan, Y., Inamoto, E., Narumiya, S. and Watanabe, N.
    • Journal Title

      Mol. Pharmacol 75

      Pages: 75-84

    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during PDGF dependent chemotaxis2009

    • Author(s)
      Monypenny, J., Zicha, D., Higashida, C., Oceguera-Yanez, F., Narumiya, S. and Watanabe, N.
    • Journal Title

      Mol.Cell. Biol. 29

      Pages: 2730-2747

    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase : requirements of myristoylation and src homology 3 domain2009

    • Author(s)
      Fujita, A., Shishido, T., Yuan, Y., Inamoto, E., Narumiya, S., Watanabe, N.
    • Journal Title

      Molecular Pharmacology 75

      Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Journal Article] Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during PDGF-dependent chemotaxis2009

    • Author(s)
      Monypenny, J., Zicha, D., Higashida, C., Oceguera-Yanez, F., Narumiya, S., Watanabe, N.
    • Journal Title

      Molecular and Cellular Biology 29

      Pages: 2730-2747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Journal Article] Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase : requirements of myristoylation and srchomology 3 domain2009

    • Author(s)
      Fujita, A., Shishido, T., Yuan, Y., Inamoto, E., Narumiya, S. and Watanabe, N.
    • Journal Title

      Molecular Pharmacology 75

      Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] An order of magnitude魚ster AIP1-associated actin disrupti on than nucleation by the Arp2/3 complex in lamellipodia2009

    • Author(s)
      Tsuji, T., Miyoshi, T., Higashida, C., Narumiya, S., Watanabe, N.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] An order of magnitude faster AIP1-associated actin disruption than nucleation by the Arp2/3 complex in lamellipodia2009

    • Author(s)
      Tsuji, T., Miyoshi, T., Higashida, C., Narumiya, S., Watanabe, N.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Journal Article] Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during PDGF-denendent chemotaxis.2009

    • Author(s)
      Monypenny, J., Zicha, D., Higashida, C., Oceguera-Yanez, F., Narumiya, S., Watanabe, N.
    • Journal Title

      Molecular and Cellular Biology 29

      Pages: 2730-2747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] G-actin regulates rapid induction of actin nucleation by mDial to restore cellular actin polymers.2008

    • Author(s)
      Higashida, C., Suetsugu, S., Tsuji, T., Monypenny, J., Narumiya, S. and Watanabe, N.
    • Journal Title

      Journal of Cell Science 121

      Pages: 3403-3412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon utgrowth2008

    • Author(s)
      Shimada T, Toriyama M, Uemura1 K, Kamiguchi H, Sugiura T, Watanabe N, *Inagaki N.
    • Journal Title

      J. Cell Biol. 181

      Pages: 817-829

    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth.2008

    • Author(s)
      Shimada, T., Toriyama, M., Uemura, K., Kamiguchi, H., Sugiura, T., Watanabe, N., Inagaki, N.
    • Journal Title

      J. Cell Biol. 181

      Pages: 817-829

    • NAID

      120005830838

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] G-actin regulates rapid induction of actin nucleation by mDial to restore cellular actin polymers.2008

    • Author(s)
      Higashida, C., Suetsugu, S., Tsuji, T., Monypenny, J., Narumiya, S., Watanabe, N.
    • Journal Title

      Journal of Cell Science 121

      Pages: 3403-3412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Shootinl interacts with actin retrograde flow and Ll-CAM to promoteaxon outgrowth2008

    • Author(s)
      Shimada, T., Toriyama, M., Uemura, K., Kamiguchi, H., Sugiura, T., Watanabe, N., and Inagaki, N.
    • Journal Title

      Journal of Cell Biology 181

      Pages: 817-829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] mDia2 Induces the Actin Scaffold for the Contractile Ring and Stabilizes its Position during Cytokinesis in NIH 3T3 Cells.2008

    • Author(s)
      Watanabe S., Ando Y., Yasuda S., Hosoya, H., Watanabe N., Ishizaki T. and Narumiya S.
    • Journal Title

      Molecular Biology of the Cell (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Shootinl interacts with actin retrograde flow and LI-CAM to promote axon outgrowth.2008

    • Author(s)
      Shimada, T., Toriyama, M., Uemura, K., Kamiguchi, H., Sugiura, T., Watanabe. N., Inagaki, N.
    • Journal Title

      Journal of Cell Biology 181

      Pages: 817-829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells.2008

    • Author(s)
      Watanabe, S., Ando, Y., Yasuda, S., Hosoya, H., Watanabe. N., Ishizaki, T., Narumiya, s.
    • Journal Title

      Molecular Biology of the Cell 19

      Pages: 2328-2338

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells.2008

    • Author(s)
      Watanabe, S., Ando, Y., Yasuda, S., Hosoya, H., Watanabe, N., Ishizaki, T., Narumiya, S.
    • Journal Title

      Mol. Biol. Cell 19

      Pages: 2328-2338

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers.2008

    • Author(s)
      Higashida, C., Suetsugu, S., Tsuji, T., Monypenny, J., Narumiya, S., Watanabe, N.
    • Journal Title

      J. Cell Sci. 121

      Pages: 3403-3412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells2008

    • Author(s)
      Watanabe S, Ando Y, Yasuda S, Hosoya H, Watanabe N, Ishizaki T, *Narumiya S.
    • Journal Title

      Mol.Biol. Cell 19

      Pages: 2328-2338

    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells.2008

    • Author(s)
      Watanabe, S., Ando, Y., Yasuda, S., Hosoya, H., Watanabe, N., Ishizaki, T., and Narumiya, S.
    • Journal Title

      Molecular Biology of the Cell 19

      Pages: 2328-2338

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers2008

    • Author(s)
      Higashida, C., Suetsugu, S., Tsuji, T., Monypenny, J., Narumiya, S. Watanabe, N.
    • Journal Title

      J. Cell Sci. 121

      Pages: 3403-3412

    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] mDia2 Induces the Actin Scaffold for the Contractile Ring and Stabilizes its Position during Cytokinesis in NIH 3T3 Cells.2008

    • Author(s)
      Watanabe S., Ando Y., Yasuda S., Hosoya, H., Watanabe N., Ishizaki T. and Narumiya S.
    • Journal Title

      Molecular Biology of the Cell (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Actin polymerization machinery in live cells as revealed by single-molecule imaging.2007

    • Author(s)
      Tsuji T., Watanabe N.
    • Journal Title

      Jpn.J.Clin.Medicine 65(2)

      Pages: 235-241

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] アクチン重合システムを解く分子イメージング:みえない脱重合反応をとらえる2007

    • Author(s)
      渡邊 直樹
    • Journal Title

      分子細胞治療 第6巻

      Pages: 77-82

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] アクチン重合システムを解く分子イメージング:みえない脱重合反応をとらえる2007

    • Author(s)
      渡邊 直樹
    • Journal Title

      分子細胞治療 第6巻

      Pages: 77-82

    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] アクチンダイナミクス2006

    • Author(s)
      渡邊直樹
    • Journal Title

      蛋白質 核酸 酵素 51

      Pages: 522-528

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] 単分子スペックル顕微鏡によるアクチンダイナミックス観察2006

    • Author(s)
      渡邊直樹
    • Journal Title

      実験医学 24

      Pages: 186-193

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] 単分子イメージングが明らかにした生細胞内アクチン重合機構2006

    • Author(s)
      辻貴宏, 渡邊直樹
    • Journal Title

      日本臨床 65

      Pages: 235-241

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] 単分子スペックル顕微鏡によるアクチンダイナミックス観察2006

    • Author(s)
      渡邊直樹
    • Journal Title

      実験医学 24

      Pages: 186-193

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] Actin dynamics2006

    • Author(s)
      Watanabe N.
    • Journal Title

      Tanpakushitsu Kakusan Koso 51(6)

      Pages: 522-528

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] Probing actin dynamics using single-molecule speckle microscopy.2006

    • Author(s)
      Watanabe N.
    • Journal Title

      Experimental Medicine 24(13)

      Pages: 186-193

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] 単分子イメージングが明らかにした生細胞内アクチン重合機構2006

    • Author(s)
      辻貴宏, 渡邊直樹
    • Journal Title

      日本臨床 65

      Pages: 235-241

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] Actin turnover-dependent fast dissociation of capping protein in the dendritic nucleation actin network : evidence of frequent filament severing.2006

    • Author(s)
      Miyoshi, T., Tsuji, T., Higashida, C., Hertzog, M., Fujita, A., Narumiya, S., Scita, G., Watanabe, N.
    • Journal Title

      Journal of Cell Biology 175

      Pages: 947-955

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] 単分子イメージングが明らかにした生細胞内アクチン重合機構2006

    • Author(s)
      辻貴宏, 渡邊直樹
    • Journal Title

      日本臨床 65

      Pages: 235-241

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] アクチンダイナミクス2006

    • Author(s)
      渡邊直樹
    • Journal Title

      蛋白質 核酸 酵素 51

      Pages: 522-528

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Actin turnover-dependent fast dissociation of capping protein in the dendritic nucleation actin network: evidence of frequent filament severing.2006

    • Author(s)
      Miyoshi, T., Tsuji, T., Higashida, C., Hertzog, M., Fujita, A., Narumiya, S., Scita, G., Watanabe, N.
    • Journal Title

      J. Cell Biol. 175

      Pages: 947-955

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] アクチンダイナミクス2006

    • Author(s)
      渡邊直樹
    • Journal Title

      蛋白質 核酸 酵素 51

      Pages: 522-528

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] Actin turnover-dependent fast dissociation of capping protein in the dendritic nucleation actin network : evidence of frequent filament severing.2006

    • Author(s)
      Miyoshi, T., Tsuji, T., Higashida, C., Hertzog, M., Fujita, A., Narumiya, S., Scita, G., Watanabe, N.
    • Journal Title

      Journal of Cell Biology 175

      Pages: 947-955

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] Actin turnover-dependent fast dissociation of capping protein in the dendritic nucleation actin network : evidence of frequent filament severing.2006

    • Author(s)
      Miyoshi, T., Tsuji, T., Higashida, C., Hertzog, M., Fujita, A., Narumiya, S., Scita, G., Watanabe, N.
    • Journal Title

      Journal of Cell Biology 175

      Pages: 947-955

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] 単分子スペックル顕微鏡によるアクチンダイナミックス観察2006

    • Author(s)
      渡邊直樹
    • Journal Title

      実験医学 24

      Pages: 186-193

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] mDialとForminファミリー:アクチン伸長端をサーフィンするプロセッシブキャッパー2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      生化学 第77巻第2号

      Pages: 136-140

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] 単分子スペックル顕微鏡がみせるアクチン重合の細胞内分子キネティクス2005

    • Author(s)
      渡邊直樹
    • Journal Title

      日本薬理学雑誌 第125巻第2号

      Pages: 103-108

    • NAID

      10014465589

    • Data Source
      KAKENHI-PROJECT-17014050
  • [Journal Article] Actin polymerization-driven motor "Formin family proteins". (article in Japanese)2005

    • Author(s)
      Watanabe N., Higashida C.
    • Journal Title

      Chemistry and Chemical Industry 58(2)

      Pages: 150-152

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] 単分子スペックル顕微鏡によるアクチン生化学の一分子イメージング2005

    • Author(s)
      東田知陽, 三好拓志, 渡邊直樹
    • Journal Title

      蛋白質核酸酵素 第50巻 第11号

      Pages: 1436-1442

    • NAID

      40006927840

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] mDialとForminファミリー:アクチン伸長端をサーフィンするプロセッシブキャッパー2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      生化学 77・2

      Pages: 136-140

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] アクチン重合駆動モーター"Forminファミリー"2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      化学と工業 第58号第2号

      Pages: 150-152

    • NAID

      10014363505

    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] 単分子スペックル顕微鏡がみせるアクチン重合の細胞内分子キネティクス2005

    • Author(s)
      渡邊直樹
    • Journal Title

      日本薬理学雑誌 第125巻 第2号

      Pages: 103-108

    • NAID

      10014465589

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] アクチン重合駆動モーター"Fominファミリー"2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      化学と工業 第58巻第2号

      Pages: 150-152

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] mDia1とForminファミリー:アクチン伸長端をサーフィンするプロセッシブキャッパー2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      生化学 77・2

      Pages: 136-140

    • NAID

      10015547849

    • Data Source
      KAKENHI-PROJECT-16022234
  • [Journal Article] アクチン重合駆動モーター"Forminファミリー"2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      化学と工業 第58巻第2号

      Pages: 150-152

    • NAID

      10014363505

    • Data Source
      KAKENHI-PROJECT-17014050
  • [Journal Article] 単分子スペックル顕微鏡がみせるアクチン重合の細胞内分子キネティクス2005

    • Author(s)
      渡邊直樹
    • Journal Title

      日本薬理学雑誌 第125巻第2号

      Pages: 103-108

    • NAID

      10014465589

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] mDialとForminファミリー:アクチン伸長端をサーフィンするプロセッシブキャッパー2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      生化学 第77巻 第2号

      Pages: 136-140

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Probing actin polymerization-driven cell motility machinery by single-molecule imaging.2005

    • Author(s)
      Watanabe N., Higashida C., Miyoshi T.
    • Journal Title

      Seibutsu Butsuri 45(6)

      Pages: 292-296

    • NAID

      10016895448

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] 単分子スペックル顕微鏡によるアクチン生化学の一分子イメージング2005

    • Author(s)
      東田知陽, 三好拓志, 渡邊直樹
    • Journal Title

      蛋白質 核酸 酵素 第50巻第11号

      Pages: 1436-1442

    • NAID

      40006927840

    • Data Source
      KAKENHI-PROJECT-17014050
  • [Journal Article] 単分子スペックル顕微鏡によるアクチン生化学の一分子イメージング2005

    • Author(s)
      東田知陽, 三好拓志, 渡邊直樹
    • Journal Title

      蛋白質 核酸 酵素 第50巻第11号

      Pages: 1436-1442

    • NAID

      40006927840

    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] 単分子スペックル顕微鏡がみせるアクチン重合の細胞内分子キネティクス2005

    • Author(s)
      渡邊直樹
    • Journal Title

      日本薬理学雑誌 125・2

      Pages: 103-108

    • NAID

      10014465589

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] mDialとForminファミリー:アクチン伸長端をサーフィンするプロセッシブキャッパー2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      生化学 第77巻第2号

      Pages: 136-140

    • Data Source
      KAKENHI-PROJECT-17014050
  • [Journal Article] アクチン重合駆動モーター"Forminファミリー"2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      化学と工業 第58巻第2号

      Pages: 150-152

    • NAID

      10014363505

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] 単分子スペックル顕微鏡によるアクチン生化学の一分子イメージング2005

    • Author(s)
      東田知陽, 三好拓志, 渡邊直樹
    • Journal Title

      蛋白質 核酸 酵素 50

      Pages: 1436-1442

    • NAID

      40006927840

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] mDia1とForminファミリー:アクチン伸長端をサーフィンするプロセッシブキャッパー2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      生化学 第77巻第2号

      Pages: 136-140

    • NAID

      10015547849

    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] アクチン重合が駆動する細胞運動の謎に挑む単分子イメージング2005

    • Author(s)
      渡邊直樹, 東田知陽, 三好拓志
    • Journal Title

      生物物理 第45巻第6号

      Pages: 292-296

    • NAID

      10016895448

    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] アクチン重合が駆動する細胞運動の謎に挑む単分子イメージング2005

    • Author(s)
      渡邊直樹, 東田知陽, 三好拓志
    • Journal Title

      生物物理 第45巻第6号

      Pages: 292-296

    • NAID

      10016895448

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] Actin polymerization kinetics in living cells disclosed by single-molecule speckle microscopy. (article in Japanese)2005

    • Author(s)
      Watanabe N.
    • Journal Title

      Forlia Pharmacol.Jpn. 125(2)

      Pages: 103-108

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] アクチン重合駆動モーター"Forminファミリー"2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      化学と工業 58・2

      Pages: 150-152

    • NAID

      10014363505

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] アクチン重合駆動モーター"Forminファミリー"2005

    • Author(s)
      渡邊直樹, 東田知陽
    • Journal Title

      化学と工業 58・2

      Pages: 150-152

    • NAID

      10014363505

    • Data Source
      KAKENHI-PROJECT-16022234
  • [Journal Article] Probing actin biochemistry in living cells using single-molecule speckle microscopy.2005

    • Author(s)
      Higashida C., Miyoshi T., Watanabe N.
    • Journal Title

      Tanpakushitsu Kakusan Koso 50(11)

      Pages: 1436-1442

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] 単分子スペックル顕微鏡によるアクチン生化学の一分子イメージング2005

    • Author(s)
      東田知陽, 三好拓志, 渡邊直樹
    • Journal Title

      蛋白質 核酸 酵素 第50巻第11号

      Pages: 1436-1442

    • NAID

      40006927840

    • Data Source
      KAKENHI-PROJECT-17049018
  • [Journal Article] mDia1 and Formins : Processive cappers surfing along with the fast-growing actin end. (article in Japanese)2005

    • Author(s)
      Watanabe N., Higashida C.
    • Journal Title

      Seikagaku 137(2)

      Pages: 136-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] 単分子スペックル顕微鏡がみせるアクチン重合の細胞内分子キネティクス2005

    • Author(s)
      渡邊直樹
    • Journal Title

      日本薬理学雑誌 125・2

      Pages: 103-108

    • NAID

      10014465589

    • Data Source
      KAKENHI-PROJECT-16022234
  • [Journal Article] 単分子スペックル顕微鏡がみせるアクチン重合の細胞内分子キネティクス2005

    • Author(s)
      渡邊直樹
    • Journal Title

      日本薬理学雑誌 第125巻第2号

      Pages: 103-108

    • NAID

      10014465589

    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] アクチン重合が駆動する細胞運動の謎に挑む単分子イメージング2005

    • Author(s)
      渡邊直樹, 東田知陽, 三好拓志
    • Journal Title

      生物物理 45

      Pages: 292-296

    • NAID

      10016895448

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390077
  • [Journal Article] アクチン重合が駆動する細胞運動の謎に挑む単分子イメージング2005

    • Author(s)
      渡邊直樹, 東田知陽, 三好拓志
    • Journal Title

      生物物理 第45巻第6号

      Pages: 292-296

    • NAID

      10016895448

    • Data Source
      KAKENHI-PROJECT-17014050
  • [Journal Article] アクチン重合が駆動する細胞運動の謎に挑む単分子イメージング2005

    • Author(s)
      渡邊直樹, 東田知陽, 三好拓志
    • Journal Title

      生物物理 第45巻 第6号

      Pages: 292-296

    • NAID

      10016895448

    • Data Source
      KAKENHI-PROJECT-17079004
  • [Journal Article] Actin polymerization-driven molecular movement of mDia1 in living cells.2004

    • Author(s)
      Higashida C., Miyoshi T., Fujita A., Oceguera-Yanez F., Monypenny J., Andou Y., Narumiya S., Watanabe N.
    • Journal Title

      Science 303(5666)

      Pages: 2007-2010

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] Actin polymerization-driven molecular movement of mDial in living cells.2004

    • Author(s)
      Higashida C., Miyoshi T., Fujita A., Oceguera-Yanez F., Monypenny J., Andou Y., Narumiya S., Watanabe N.
    • Journal Title

      Science 303

      Pages: 2007-2010

    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] Formins : Processive cappers of growing actin filaments.2004

    • Author(s)
      Watanabe, N., Higashida, C.
    • Journal Title

      Experimental Cell Research 301

      Pages: 16-22

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] Formins : Processive cappers of growing actin filaments.2004

    • Author(s)
      Watanabe N., Higashida C.
    • Journal Title

      Experimental Cell Research 301

      Pages: 16-22

    • Data Source
      KAKENHI-PROJECT-16022234
  • [Journal Article] Actin polymerization-driven molecular movement of mDial in living cells.2004

    • Author(s)
      Higashida, C., Miyoshi, T., Fujita, A., Oceguera-Yanez, F., Monypenny, J., Andou, Y., Narumiya, S., Watanabe, N.
    • Journal Title

      Science 303

      Pages: 2007-2010

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] Formins : Processive cappers of growing actin filaments.2004

    • Author(s)
      Watanabe N., Higashida C.
    • Journal Title

      Experimental Cell Research 301

      Pages: 16-22

    • Data Source
      KAKENHI-PROJECT-15370086
  • [Journal Article] Actin polymerization-driven molecular movement of mDia1 in living cells.2004

    • Author(s)
      Higashida C., Miyoshi T., Fujita A., Oceguera-Yanez F., Monypenny J., Andou Y., Narumiya S., Watanabe N.
    • Journal Title

      Science 303

      Pages: 2007-2010

    • Data Source
      KAKENHI-PROJECT-16022234
  • [Journal Article] Shootinl interacts with actin retrograde flow and L1-CAM to promote axono utgrowth.

    • Author(s)
      Shimada T., Toriyama M., Uemura K., Kamiguchi H., Sugiura T, , Watanabe N. and Inagaki N.
    • Journal Title

      Journal of Cell Biology (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Journal Article] Shootinl interacts with actin retrograde flow and L1-CAM to promote axon outgrowth.

    • Author(s)
      Shimada T, Toriyama M., Uemura K., Kamiguchi H, Sugiura T., Watanabe N. and Inagaki N.
    • Journal Title

      Journal of Cell Biology (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Patent] 多重抗原検出用抗体2023

    • Inventor(s)
      渡邊直樹、宮本章歳、張千里
    • Industrial Property Rights Holder
      国立大学法人京都大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Patent] 多重抗原検出用抗体2022

    • Inventor(s)
      渡邊直樹、宮本章歳、張千里
    • Industrial Property Rights Holder
      国立大学法人京都大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-126485
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] 無制限多重染色を実現する超解像顕微鏡と細胞マーカー検出のためのモノクローナル抗体断片変異導入戦略2023

    • Author(s)
      宮本 章歳、渡邊 直樹
    • Organizer
      第46回日本分子生物学会年会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Vinculin-talin complexes flow over mature focal adhesions as revealed by fluorescence single-molecule speckle (SiMS) microscopy2023

    • Author(s)
      劉穎、山城佐和子、渡邊直樹
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Live-cell fluorescence single-molecule speckle (SiMS) microscopy analysis of Vinculin-Talin and actin network2023

    • Author(s)
      劉穎、山城佐和子、渡邊直樹
    • Organizer
      第75回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] 次世代超解像イメージングIRISのための抗体改変プローブ2023

    • Author(s)
      渡邊直樹、張千里、宮本章歳、有森貴夫、高木淳一
    • Organizer
      生体運動研究合同班会議 2023
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Talin の elastic transient clutch による力伝達機構2023

    • Author(s)
      山城佐和子、David M. Rutkowski、Kelli Ann Lynch、Dimitrios Vavylonis、渡邊直樹
    • Organizer
      第75回日本細胞生物学会大会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] 細胞内蛍光単分子イメージングで明らかにする流動力伝達の仕組み2023

    • Author(s)
      山城佐和子、渡邊直樹
    • Organizer
      第46回日本分子生物学会年会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Force Transmission via dynamic stretching of Talin as revealed by live-cell single-molecule imaging2023

    • Author(s)
      Sawako Yamashiro, David M. Rutkowski, Kelli Ann Lynch, Ying Liu, Dimitrios Vavylonis, Naoki Watanabe
    • Organizer
      American Physical Society March Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] 蛍光単分子イメージングで明らかにする細胞内力伝達機構2023

    • Author(s)
      山城佐和子、David M. Rutkowski、Kelli Ann Lynch、Ying Liu、Dimitrios Vavylonis、渡邊直樹
    • Organizer
      第61回日本生物物理学会年会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Quantitative analysis of paxillin dynamics measured by live-cell fluorescence single-molecule speckle (SiMS) microscopy2023

    • Author(s)
      楊雅婷、山城佐和子、渡邊直樹
    • Organizer
      第75回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Force sensing at the lamellipodium tip by actin barbed ends: Brownian ratchet relationship or catastrophic disassembly?2023

    • Author(s)
      Naoki Watanabe
    • Organizer
      第75回日本細胞生物学会大会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Engineered fast-dissociating recombinant antibody and synapse molecular mapping by IRIS super-resolution imaging2022

    • Author(s)
      張千里、宮本章歳、有森貴夫、木内泰、高木淳一、渡邊直樹
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Translation of mechanical forces into cell structure remodeling revealed by single-molecule imaging2022

    • Author(s)
      Naoki Watanabe
    • Organizer
      9th World Congress of Biomechanics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Single-molecule speckle (SiMS) analysis of vinculin-actin interaction in lamellipodia2022

    • Author(s)
      Ying LIU, Sawako YAMASHIRO, Naoki WATANABE
    • Organizer
      2022年生体運動研究合同班会議
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Motion Analysis Of Actin Oligomer In Lamellipodia By SiMS Microscopy2022

    • Author(s)
      臼倉英治、山城佐和子、渡邊直樹
    • Organizer
      2022年生体運動研究合同班会議
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] 迅速解離リコンビナント抗体によるシナプス分子の超解像マッピング2022

    • Author(s)
      張千里、宮本章歳、有森貴夫、木内泰、高木淳一、渡邊直樹
    • Organizer
      第95回生化学会
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] チロシンキナーゼ阻害薬が引き起こす逆説的Src活性化とがん細胞増殖2022

    • Author(s)
      渡邊直樹、樋口牧郎
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] 抗がんキナーゼ阻害薬が標的を活性化する危険性2022

    • Author(s)
      渡邊直樹
    • Organizer
      2022年生体運動研究合同班会議
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Development of fast-dissociating recombinant antibody probes for multiplexed super-resolution molecular mapping2022

    • Author(s)
      張千里、宮本章歳、有森貴夫、木内泰、高木淳一、渡邊直樹
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy IRIS2022

    • Author(s)
      Qianli Zhang , Akitoshi Miyamoto, Takao Arimori, Tai Kiuchi, Junichi Takagi, Naoki Watanabe
    • Organizer
      KU-OIST Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] ずり応力が引き起こす細胞膜分子勾配形成の蛍光1分子イメージング解析2022

    • Author(s)
      山城佐和子、野村実里、渡邊直樹
    • Organizer
      第74回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-22H00456
  • [Presentation] Contemplation on ‘spare molecules’ in G/F-actin homeostasis and formin homology proteins2021

    • Author(s)
      Naoki Watanabe
    • Organizer
      第73回日本細胞生物学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Paradoxical Src activation and cancer cell proliferation induced by tyrosine kinase inhibitors2021

    • Author(s)
      Naoki Watanabe and Makio Higuchi
    • Organizer
      CellBio Virtual 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] 抗がん薬による逆説的な細胞増殖促進&先導端アクチンの動的不安定性2021

    • Author(s)
      渡邊直樹
    • Organizer
      「認識と形成」研究会
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] アクチン線維流動と接着斑分子ダイナミクスの定量的単分子イメージング解析2021

    • Author(s)
      山城佐和子、劉穎、渡邊直樹
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] 高精度単分子イメージングによるアクチン繊維流動-接着斑連関の可視化解明2021

    • Author(s)
      山城佐和子、劉穎、渡邊直樹
    • Organizer
      第73回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] New insights into the retrograde F-actin flow associated motions of focal adhesion molecules visualized by single-molecule speckle (SiMS) microscopy2020

    • Author(s)
      Sawako Yamashiro, Ying Liu, Dimitrios Vavylonis, Naoki Watanabe
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] ラメリポディアが動物細胞に普遍的に存在する理由2020

    • Author(s)
      渡邊 直樹、山城 佐和子
    • Organizer
      生体運動研究合同班会議 2020
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Retrograde actin flow-associated motions of focal adhesion molecules visualized by single-molecule speckle (SiMS) microscopy2020

    • Author(s)
      Sawako Yamashiro, Ying Liu, Naoki Watanabe
    • Organizer
      American Society for Cell Biology/EMBO Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Translation of mechanical forces through cellular actin systems2019

    • Author(s)
      Naoki Watanabe
    • Organizer
      The 11th TOYOTA RIKEN International Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] The change of the direction of F-actin caused by the filament disassembly around focal adhesions2019

    • Author(s)
      Kiyoshi Tohyama, Sawako Yamashiro, Naoki Watanabe
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] 無制限多重染色と高精細画像を実現した超解像顕微鏡IRIS2019

    • Author(s)
      渡邊 直樹
    • Organizer
      JASIS 2019 ライフサイエンスイノベーションゾーン基調講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Coupling between actin retrograde flow and focal adhesion molecules visualized by single-molecule speckle microscopy2019

    • Author(s)
      Yamashiro S, Liu Y, Watanabe N
    • Organizer
      American Society for Cell Biology / EMBO 2019 meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] 単分子イメージングによるアクチン線維流動-接着斑分子連結機構の可視化解明2019

    • Author(s)
      山城 佐和子、劉 穎、渡邊 直樹
    • Organizer
      第19回日本蛋白質科学会・第71回日本細胞生物学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Single-Molecule Dissection of Physico-Biochemical Coupling in Actin System2019

    • Author(s)
      Naoki Watanabe
    • Organizer
      ZEISS-iCeMS Innovation Core Founding Commemorative Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Visualizing the rotation of single actin filaments in living cells2019

    • Author(s)
      通山 潔、山城 佐和子、渡邊 直樹
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Retrograde flow-induced biased distribution of actin probes in live cells2019

    • Author(s)
      Yamashiro S, Taniguchi D, Tanaka S, Kiuchi T, Vavylonis D, Watanabe N.
    • Organizer
      The 11th TOYOTA RIKEN International Workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01020
  • [Presentation] Single-molecule observation of mechanosensitive actin polymerization by Formins2011

    • Author(s)
      Watanabe N.
    • Organizer
      The 2nd UCL-Tohoku symposium
    • Place of Presentation
      仙台
    • Year and Date
      2011-01-23
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Presentation] Mechanosensitive actin nucleation by mDia1 and a possible role of actin polymer homeostasis2010

    • Author(s)
      Watanabe N.
    • Organizer
      "The Cellular Cytoskeleton : Common Organizing Principles in Mitosis, Motility and Cell Polarization" Conference
    • Place of Presentation
      米国コロラド州フォートコリンズ
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Presentation] Regulation of processive actin nucleation and elongation by Formins visualized by single-molecule imaging2010

    • Author(s)
      Mizuno H., Higashida C., Watanabe N.
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Presentation] 細胞内分子イメージングと低分子化合物研究の融合に向けて2010

    • Author(s)
      渡邊直樹
    • Organizer
      第2回定量生物の会
    • Place of Presentation
      大阪
    • Year and Date
      2010-01-10
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Presentation] Mechanosensitive actin nucleation and filament regeneration2010

    • Author(s)
      Watanabe N., Mizuno H., Masahiro M., Higashida C.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Presentation] 細胞内分子イメージングと低分子化合物研究の融合に向けて2010

    • Author(s)
      渡邊直樹
    • Organizer
      第2回定量生物の会
    • Place of Presentation
      大阪
    • Year and Date
      2010-01-10
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] STI571 induced cell edge translocation of abl kinase2009

    • Author(s)
      Yuan Y., Fujita A., Shishido T., Narumiya S., Watanabe N
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜(speaker)
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] Rapid actin polymer restoration against mechanical force : Roles of G-and F-actin homeostasis and mDial2009

    • Author(s)
      Watanabe. N., Higashida, C., Mizuno, H.
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] STI571に誘導されるablの細胞辺縁トランスロケーション2009

    • Author(s)
      Yuan Y., Fujita A., Shishido T., Narumiya S., Watanabe N. (speaker)
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] A Role of G-and F-actin Homeostasis in Actin Polymer Resto ration2009

    • Author(s)
      Watanabe. N., Higashida, C., Mizuno, H.
    • Organizer
      Symposium on Watching Biomolecules in Action
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-15
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] STI571-induced cell edge translocation of abl kinase.2009

    • Author(s)
      Yuan Y., Fujita A., Shishido T., Narumiya S., ○Watanabe N. (○:speaker)
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] A Role of G- and F-actin Homeostasis in Actin Polymer Restoration2009

    • Author(s)
      Watanabe, N., Higashida, C., Mizuno, H.
    • Organizer
      Symposium on Watching Biomolecules in Action
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-15
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Presentation] STI571に誘導されるablめ細胞辺縁トランスロケーション2009

    • Author(s)
      Yuan Y., Fujita A., Shishido T., Narumiya S.,Watanabe N. (speaker)
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Rapid actin polymer restoration against mechanical force : Roles of G- and F-actin homeostasis and mDia12009

    • Author(s)
      Watanabe, N., Higashida, C., Mizuno, H.
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-21390078
  • [Presentation] A Role of G- and F-actin Homeostasis in Actin Polymer Restoration.2009

    • Author(s)
      Watanabe N., Higashida C., Mizuno H.
    • Organizer
      Symposium on Watching Biomolecules in Action
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-15
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Rapid actin polymer restoration against mechanical force: Roles of G- and F-actin homeostasis and mDia1.2009

    • Author(s)
      Watanabe N., Higashida C., Mizuno H.
    • Organizer
      第61回日本細胞生物学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Rapid actin polymer restoration mechanism by mDia1 and othe actin nucleators regulated by concentration fluctuation of G-actin2008

    • Author(s)
      Higashida C., Suetsugu S., Narumiya S., Watanabe N.
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会シンポジウム(企画・主催)
    • Place of Presentation
      神戸(speaker)
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] A role of homeostasis between G- and F-actin in filament nucleation and actin polymer restoration by mDial.2008

    • Author(s)
      Higashida C., Watanabe N.
    • Organizer
      第48回アメリカ細胞生物学会
    • Place of Presentation
      米国サンフランシスコ
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] A paradoxical effect of actin monomer inhibitors to increase drug-free G-actin in cells : an unexpected role of G-actin revealed by pharmacokinetic simulation2008

    • Author(s)
      Watanabe, N. and Higashida,C.
    • Organizer
      THE. UEHARA MEMORIAL FOUNDATION SYMPOSIUM-2008 Systems Biology : The Challenge of Complexity
    • Place of Presentation
      東京
    • Year and Date
      2008-07-01
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] (speaker) Rapid actin polymer restoration mechanism by mDia1 and other actin nucleators regulated by concentration fluctuation of G-actin.2008

    • Author(s)
      Higashida C., Suetsugu S., Narumiya S., Watanabe N.
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会シンポジウム(企画・主催)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] A paradoxical effect of actin monomer inhibitors to increase drug free G actin in cells : an unexpected role of G actin revealed by pharmacokinetic simulation2008

    • Author(s)
      Watanabe N., Higashida C.
    • Organizer
      The Uehara Memorial Foundation Symposium 2008.; Systems Biology : the Challenge of Complexity
    • Place of Presentation
      東京
    • Year and Date
      2008-07-01
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] A role of homeostasis between G-and F-actin in filament nucleation and actin polymer restoration by mDial2008

    • Author(s)
      Higashida C., Watanabe N.
    • Organizer
      第48回アメリカ細胞生物学会
    • Place of Presentation
      米国サンフランシスコ
    • Year and Date
      2008-12-15
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Rapid actin polymer restoration mechanism by mDial and other actin nucleators regulated by concentration fluctuation of G-actin2008

    • Author(s)
      Higashida C., Suetsugu S., Narumiya S., Watanabe N. (speaker)
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(備考 : シンポジウム主催)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] A paradoxical effect of actin monomer inhibitors to increase drug-free G-actin in cells : an unexpected role of G-actiti revealed by pharmacokinetic simulation.2008

    • Author(s)
      Watanabe, N., Higashida, C.
    • Organizer
      THE UEHARA MEMORIAL FOUNDATIONSYMPOSIUM-2008 Systems Biology : The Challenge of Complexity
    • Place of Presentation
      東京
    • Year and Date
      2008-07-01
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] Rapid actin polymer restoration mechanism by mDial and other actin nucleators regulated by concentration fluctuation of G-actin.2008

    • Author(s)
      Higashida C., Suetsugu S., Narumiya S., Watanabe N. (speaker)
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(備考 : シンポジウム主催)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] A paradoxical effect of actin monomer inhibitors to increase drug-free G-actin in cells: an unexpected role of G-actin revealed by pharmacokinetic simulation.2008

    • Author(s)
      Watanabe N., Higashida C.
    • Organizer
      The Uehara Memorial Foundation Symposium 2008. Systems Biology: the Challenge of Complexity
    • Place of Presentation
      東京
    • Year and Date
      2008-07-01
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] 細胞内G&Fアクチンのホメオスターシス2007

    • Author(s)
      渡邊 直樹
    • Organizer
      「アクチン・ミオシン:分子と細胞を如何にして結び付けるか」の会(特定領域研究「生体ナノシステムの制御」主催)
    • Place of Presentation
      東京(早稲田大学)
    • Year and Date
      2007-11-10
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Lessons from single-molecule microscopy of cellular actin systems. Part1: frequent severing-annealing of filaments.2007

    • Author(s)
      Watanabe N., Higashida C. (joint speaker)
    • Organizer
      Part 2: acute filament restoration by mDia1. 英国癌研究所(Cancer Research UK)
    • Place of Presentation
      イギリスロンドン
    • Year and Date
      2007-05-10
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Molecular kinetics of AIP1, a cofilin-dependent actin barbed end interacting protein. in lamellipodia: Evidence for frequent filament severing.2007

    • Author(s)
      Naoki Watanabe
    • Organizer
      SEMM Workshop on Cell Migration: from Molecules to Organisms and Diseases.
    • Place of Presentation
      イタリア・ミラノ
    • Year and Date
      2007-05-13
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] 細胞内G&Fアクチンのホメオスターシス2007

    • Author(s)
      渡邊 直樹
    • Organizer
      「アクチン・ミオシン:分子と細胞を如何にして結び付けるか」の会(特定領域研究「生体ナノシステムの制御」主催)
    • Place of Presentation
      東京(早稲田大学)
    • Year and Date
      2007-11-10
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] Challenging frequent filament severing annealing hypothesis by single molecule imaging of AIP1, a cofilin dependent actin barbed end interacting protein2007

    • Author(s)
      Watanabe N., Higashida C., Tsuji T.
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大8会合同大会ワークショップ(企画・主催)
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] 細胞内G&Fアクチンのホメオスターシス「アクチン・ミオシン:分子と細胞を如何にして結び付けるか」2007

    • Author(s)
      渡邊直樹
    • Organizer
      の会(特定領域研究「生体ナノシステムの制御」主催
    • Place of Presentation
      東京・早稲田大学
    • Year and Date
      2007-11-10
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Challenging frequent filament severing-annealing hypothesis by single-molecule imaging of AIP1, a cofilin-dependent actin barbed end interacting protein.2007

    • Author(s)
      Watanabe N., Higashida C., Tsuji T.
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大8会合同大会ワークショップ(企画・主催)
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Challenging frequent filament severing-annealing hypothesis by single-molecule imaging of AIP1, a cofilin-dependent actin barbed end interacting protein.2007

    • Author(s)
      Naoki Watanabe
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] Molecular kinetics of AIP1, a cofilin-dependent actin barbed end interacting protein, in lamellipodia: Evidence for frequent filament severing.2007

    • Author(s)
      Naoki Watanabe
    • Organizer
      SEMM Workshop on Cell Migration: from Molecules to Organisms and Diseases.
    • Place of Presentation
      イタリア・ミラノ
    • Year and Date
      2007-05-13
    • Data Source
      KAKENHI-PROJECT-19390075
  • [Presentation] (○: speaker) Molecular kinetics of AIP1, a cofilin-dependent actin barbed end interacting protein, in lamellipodia: Evidence for frequent filament severing.2007

    • Author(s)
      Tsuji T., Higashida C., ○Watanabe N.
    • Organizer
      SEMM Workshop on Cell Migration: from Molecules to Organisms and Diseases
    • Place of Presentation
      イタリアミラノ
    • Year and Date
      2007-05-13
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Challenging frequent filament severing-annealing hypothesis by single-molecule imaging of AIP1, a cofilin-dependent actin barbed end interacting protein.2007

    • Author(s)
      Naoki Watanabe
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Acute actin polymerization mechanisms by mDia1 in living cells.2006

    • Author(s)
      渡邊直樹
    • Organizer
      日本分子生物学会2006フォーラム
    • Place of Presentation
      名古屋
    • Year and Date
      2006-12-06
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Molecular Kinetics of the Arp 2/3 Complex and Capping Proteins at the Leading Edge.2005

    • Author(s)
      Miyoshi T., Higashida C., ○Watanabe N. (○: speaker)
    • Organizer
      Keystone Symposia, Cell Migration and Adhesion
    • Place of Presentation
      日米国ユタ州スノーバード
    • Year and Date
      2005-04-10
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] 単分子イメージングによる細胞内アクチン重合機構の解析2005

    • Author(s)
      渡邊直樹
    • Organizer
      第14回日本バイオイメージング学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2005-10-27
    • Data Source
      KAKENHI-PROJECT-17079004
  • [Presentation] Evidence of constitutive actin filament severing in lamellipodia.2005

    • Author(s)
      Miyoshi T., Higashida C., ○Watanabe N. (○: speaker)
    • Organizer
      第58回日本細胞生物学会大会
    • Place of Presentation
      埼玉県大宮
    • Year and Date
      2005-06-17
    • Data Source
      KAKENHI-PROJECT-17079004
  • 1.  TASHIRO Kei (10263097)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  NAKAMURA Takashi (10201675)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  ITO Hiromu (70397537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  橋本 信夫 (40135570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  荒川 芳輝 (20378649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  山城 佐和子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 7.  平田 多佳子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  木内 泰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  宮本 章歳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  三木 貴雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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