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Kurokawa Kenji  黒川 健児

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… Alternative Names

KUROKAWA KENJI  黒川 健児

黒川 健児  クロカワ ケンジ

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Researcher Number 80304963
Other IDs
Affiliation (Current) 2025: 長崎国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2013 – 2017: 長崎国際大学, 薬学部, 准教授
2004 – 2005: 東京大学, 大学院・薬学系研究科, 講師
2002 – 2003: 東京大学, 大学院・薬学系研究科, 助手
2001: 東京大学, 大学院・薬学研究科, 助手
2000: 長崎大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Environmental and hygienic pharmacy / Biological pharmacy / Biological pharmacy
Except Principal Investigator
Biological Sciences / Bacteriology (including mycology) / Biological pharmacy
Keywords
Principal Investigator
黄色ブドウ球菌 / DNA複製 / 細胞壁タイコ酸 / 免疫賦活化 / 細菌宿主相互作用 / DnaAタンパク質 / グラム陽性菌 / 塩基性リン脂質 / 酸性リン脂質 / ATP結合 … More / DnaA蛋白 / 樹状細胞 / ドイツ / アメリカ合衆国 / 韓国 / 国際情報交換 / 韓国:米国:ドイツ / DnaIタンパク質 / DnaBタンパク質 / グラム陽性最近 / 複製開始 / AAA+タンパク質 / oriC / dnaD遺伝子 / mprF遺伝子 / AAAスーパーファミリー蛋白質 / DNAポリメラーゼIII βサブユニット / DNA複製伸長装置 / ATPase / 大腸菌 / DNA複製開始調節 / DnaA蛋白質 … More
Except Principal Investigator
MIP-T3 / IL13RBP1 / TRAF3 / IL-13 / インターロイキン / 大型ウイルス / 進化 / 黄色ブドウ球菌 / MRSA / 普遍形質導入 / 遺伝子の水平伝播 / ファージ / signaltransduction / STATG / Yeast tri-hybrid / レセプター / シグナル伝達 / サイトカイン / Th2 / アレルギー / インターロイキン13 / signal transduction / STAT6 / HeLa細胞 / カスパーゼ / RNAi / ICRF-193 / マウス初期胚 / 遺伝子ノックアウトマウス / DNAトポイソメラーゼ / アポトーシス / 酵母細胞 / シュナイダー細胞 / 血清飢餓 / G0期 / ノックアウトマウス / 細胞周期 / トポイソメラーゼ / イムノトキシン / 遺伝子治療 / アデノウイルス Less
  • Research Projects

    (9 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (14 People)
  •  Identification of innate immune ligands to induce the protection from MRSA infectionPrincipal Investigator

    • Principal Investigator
      Kurokawa Kenji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      Nagasaki International University
  •  Analysis of MRSA evolution mechanism by generalized transduction

    • Principal Investigator
      UCHIYAMA JUMPEI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Azabu University
  •  Protection against MRSA infection using conserved antigen among Gram-positive bacterial cell surfacePrincipal Investigator

    • Principal Investigator
      KUROKAWA KENJI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      Nagasaki International University
  •  黄色ブドウ球菌の染色体複製開始因子DnaAの機能制御Principal Investigator

    • Principal Investigator
      黒川 健児
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  マウスDNAトポイソメラーゼIIαの細胞周期制御における役割に関する分子遺伝学

    • Principal Investigator
      関水 和久
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  黄色ブドウ球菌の複製開始因子DnaAの生化学的解析とその活性制御因子の新規同定Principal Investigator

    • Principal Investigator
      黒川 健児
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  アデノウイルスベクターによるIL-13Rα2遺伝子の癌細胞への導入-IL13トキシンによる癌遺伝子治療

    • Principal Investigator
      MURATA Takashi
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagasaki University
  •  染色体DNA複製開始蛋白DnaAの活性調節因子の新規同定Principal Investigator

    • Principal Investigator
      黒川 健児
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
      Nagasaki University
  •  CHARACTERIZATION OF SIGNAL TRANSDUCTION SYSTEM OF IL-13 RECEPTOR -MOLECULAR CLONING OF A NOVEL SIGNAL TRANSDUCTION MOLECULES FOR IL-13 SIGNALING.

    • Principal Investigator
      MURATA Takashi
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagasaki University

All 2017 2016 2015 2014 2013 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Adsorption of Staphylococcus viruses S13´ and S24-1 on Staphylococcus aureus strains with different glycosidic linkage patterns of wall teichoic acids.2017

    • Author(s)
      Uchiyama, J., Taniguchi, M., Kurokawa, K., Takemura-Uchiyama, I., Ujihara, T., Shimakura, H., Sakaguchi, Y., Murakami, H., Sakaguchi, M., Matsuzaki, S.
    • Journal Title

      J. Gen. Virol.

      Volume: 98(8) Issue: 8 Pages: 2171-2180

    • DOI

      10.1099/jgv.0.000865

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08785, KAKENHI-PROJECT-17K15385, KAKENHI-PROJECT-15K07756, KAKENHI-PROJECT-15K08056, KAKENHI-PROJECT-15K10756, KAKENHI-PROJECT-15K19095
  • [Journal Article] The staphylococcal surface-glycopolymer wall teichoic acid (WTA) is crucial for complement activation and immunological defense against Staphylococcus aureus infection.2016

    • Author(s)
      Kurokawa K, Takhashi K, and Lee BL.
    • Journal Title

      Immunobiology

      Volume: 221 Issue: 10 Pages: 1091-1101

    • DOI

      10.1016/j.imbio.2016.06.003

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08056
  • [Journal Article] ヒト血清による黄色ブドウ球菌の認識と貪食の誘導機構2015

    • Author(s)
      黒川健児
    • Journal Title

      化学と生物

      Volume: 53 Pages: 319-325

    • NAID

      130005146581

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Journal Article] Human anti-peptidoglycan-IgG-mediated opsonophagocytosis is controlled by calcium mobilization in phorbol myristate acetate-treated U937 cells.2015

    • Author(s)
      Kim MJ, Rah SY, An JH, Kurokawa K, Kim UH, and Lee BL.
    • Journal Title

      BMB Rep.

      Volume: 48 Pages: 36-41

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Journal Article] Surface glycopolymers are crucial for in vitro anti-wall teichoic acid IgG-mediated complement activation and opsonophagocytosis of Staphylococcus aureus.2015

    • Author(s)
      Lee JH, Kim NH, Winstel V, Kurokawa K, Larsen J, An JH, Khan A, Seong MY, Lee MJ, Andersen PS, Peschel A, and Lee BL.
    • Journal Title

      Infect Immun.

      Volume: 83 Issue: 11 Pages: 4247-4255

    • DOI

      10.1128/iai.00767-15

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08056
  • [Journal Article] ヒト血清による黄色ブドウ球菌の認識と貪食の誘導機構2015

    • Author(s)
      黒川健児
    • Journal Title

      KAGAKU TO SEIBUTSU

      Volume: 53 Issue: 5 Pages: 319-325

    • DOI

      10.1271/kagakutoseibutsu.53.319

    • NAID

      130005146581

    • ISSN
      0453-073X, 1883-6852
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08056
  • [Journal Article] Human SAP is a novel peptidoglycan recognition protein that induces complement-independent phagocytosis of Staphylococcus aureus.2013

    • Author(s)
      An JH, Kurokawa K, Jung DJ, Kim MJ, Kim CH, Fujimoto Y, Fukase K, Coggeshall KM, and Lee BL.
    • Journal Title

      J. Immunol.

      Volume: 191 Issue: 6 Pages: 3319-3327

    • DOI

      10.4049/jimmunol.1300940

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Journal Article] Intradermal immunization with wall teichoic acid (WTA) elicits and augments an anti-WTA IgG response that protects mice from methicillin-resistant Staphylococcus aureus infection independent of mannose-binding lectin status.2013

    • Author(s)
      Takahashi K, Kurokawa K, Moyo P, Jung DJ, An JH, Chigweshe L, Paul E, and Lee BL.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 8 Pages: e69739-e69739

    • DOI

      10.1371/journal.pone.0069739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Journal Article] Glycoepitopes of staphylococcal wall teichoic acid govern complement-mediated opsonophagocytosis via human serum antibody and mannose-binding lectin.2013

    • Author(s)
      Kurokawa K, Jung DJ, An JH, Fuchs K, Jeon YJ, Kim NH, Li X, Tateishi K, Park JA, Xia G, Matsushita M, Takhashi K, Park HJ, Peschel A, and Lee BL.
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Issue: 43 Pages: 30956-30968

    • DOI

      10.1074/jbc.m113.509893

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Journal Article] Isolation of a temperature-sensitive dnaA mutant of Staphylococcus aureus.2006

    • Author(s)
      Murai, M., Kurokawa, K., et al.
    • Journal Title

      FEMS Microbiol Lett. 254・1

      Pages: 19-26

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Journal Article] Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from S.aureus.2006

    • Author(s)
      Nishida, S., Kurokawa, K., et al.
    • Journal Title

      J.Biol.Chem. 281・3

      Pages: 1714-1724

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Journal Article] Participation of Rho-dependent transcription termination in oxidative stress sensitivity caused by an rpoB mutation.2005

    • Author(s)
      Kawamura, N., Kurokawa, K., et al.
    • Journal Title

      Genes Cells 10・5

      Pages: 477-487

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Journal Article] Induction of fusion-component myoblast-specific gene expression during myogenic differentiation of Drosophila Schneider cells by DNA double-strand or replication inhibition.2005

    • Author(s)
      Hossain, M.S., Kurokawa, K., Sekimizu, K
    • Journal Title

      B.B.A. 1743・1-2

      Pages: 176-186

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Journal Article] Silkworm-pathogenic bacteria infection model for identification of novel virulence genes.2005

    • Author(s)
      Kaito, C., Kurokawa, K., et al.
    • Journal Title

      Molecular Microbiology (In press)

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Journal Article] Silkworm-pathogenic bacteria infection model for identification of novel virulence genes.2005

    • Author(s)
      Kaito.C., Kurokawa.K., et al.
    • Journal Title

      Mol.Microbiol. 56・4

      Pages: 934-944

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Journal Article] Participation of Rho-dependent transcription termination in oxidatvie stress sensitivity caused by an rpoB mutation.2005

    • Author(s)
      Kawamura, N., Kurokawa, K., et al.
    • Journal Title

      Genes to Cells 10

      Pages: 477-487

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Journal Article] DNA topoiomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast.2004

    • Author(s)
      Hossain, M.S., Kurokawa, K., Akimitsu, N., Sekimizu, K.
    • Journal Title

      Genes to Cells 9・10

      Pages: 905-917

    • Data Source
      KAKENHI-PROJECT-16689003
  • [Presentation] Staphylococcus viruses S13' and S24-1 on Staphylococcus aureus strains with different glycosidic linkage patterns of wall teichoic acids.2017

    • Author(s)
      Uchiyama J, Taniguchi M, Kurokawa K, Takemura-Uchiyama I, Ujihara T, Shimakura H, Sakaguchi Y, Murakami H, Sakaguchi M, and Matsuzaki S.
    • Organizer
      The 16th Awaji International Forum on Infection and Immunity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08056
  • [Presentation] Analysis of adsorption of phages, S13' and S24-1, belonging to the family Podoviridae genus P68virus, using Staphylococcus aureus strains with different glycosidic linkage patterns of wall teichoic acids.2017

    • Author(s)
      Uchiyama J, Kurokawa K, Takemura-Uchiyama I, Ujihara T, Sakaguchi Y, Sakaguchi M, and Matsuzaki S.
    • Organizer
      International Union of Microbiology Societies (IUMS) 2017 congresses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08056
  • [Presentation] Analysis of adsorption of phages, S13’ and S24-1, belonging to the family Podoviridae genus P68virus, using Staphylococcus aureus strains with different glycosidic linkage patterns of wall teichoic acids2017

    • Author(s)
      Jumpei Uchiyama, Kenji Kurokawa, Iyo Takemura-Uchiyama, Takako Ujihara, Yoshihiko, Sakaguchi, Masahiro Sakaguchi, Shigenobu Matsuzaki
    • Organizer
      IUMS (International Union of Microbiological Societies Congress) 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19095
  • [Presentation] Adsorption of Staphylococcus viruses S13' and S24-1 on Staphylococcus aureus strains with different glycosidic linkage patterns of wall teichoic acids2017

    • Author(s)
      Jumpei Uchiyama, Maya Taniguchi, Kenji Kurokawa, Iyo Takemura-Uchiyama, Takako Ujihara, Hidekatsu Shimakura, Yoshihiko Sakaguchi, Hironobu Murakami, Masahiro Sakaguchi, Shigenobu Matsuzaki
    • Organizer
      The 16th Awaji International Forum on Infection and Immunity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19095
  • [Presentation] Study of adsorption of AHJD-like phages infecting Staphylococcus aureus2017

    • Author(s)
      内山淳平、黒川健児、内山伊代、氏原隆子、阪口義彦、松崎茂展、阪口雅弘
    • Organizer
      第90回日本細菌学会総会
    • Place of Presentation
      仙台国際センター、宮城県
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-15K19095
  • [Presentation] Surface-glycopolymers are crucial for anti-WTA IgG-mediated complement activation and opsonophagocytosis of Staphylococcus aureus.2015

    • Author(s)
      Lee JH, Kim NH, Kurokawa K, and Lee BL.
    • Organizer
      第52回日本補体学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-15K08056
  • [Presentation] 各種ファージに対する黄色ブドウ球菌受容体の解析2015

    • Author(s)
      内山淳平、黒川健児、阪口義彦、内山(竹村)伊代、氏原隆子、村上雅尚、大畑雅典、松崎茂展
    • Organizer
      第88回日本細菌学会総会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] Complement classical and lectin pathways utilize S. aureus wall teichoic acid glycoepitopes2014

    • Author(s)
      Kurokawa K
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] 黄色ブドウ球菌に対するレクチンと主要抗体は細胞壁タイコ酸の修飾糖をエピトープとする2014

    • Author(s)
      黒川健児, 高橋和枝, 松下操, 姫野勝, 李副律
    • Organizer
      第59回日本ブドウ球菌研究会
    • Place of Presentation
      東京農工大学(府中)
    • Year and Date
      2014-08-04
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] Wall teichoic acid glycoepitopes govern innate and adaptive host defense against Staphylococcus aureus2013

    • Author(s)
      Kurokawa K, Jung DJ, An JH, Jeon YJ, Kim NH, Matsushita M, Himeno M, Lee BL
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] tarS-harboring Staphylococcus aureus strains are opsonophagocytosed by human anti-wall teichoic acid-IgG.

    • Author(s)
      Kim NH, Lee JH, Winstel V, Kurokawa K, An JH, Khan A, Seong MY, Lee MJ, Peschel A, and Lee BL.
    • Organizer
      The 16th International Symposium on Staphylococci and Staphylococcal Infections.
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2014-08-26 – 2014-08-29
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] 微生物リガンドの同定によって垣間見る、細菌と自然免疫の攻防

    • Author(s)
      黒川 健児
    • Organizer
      第4回薬学研究発表会
    • Place of Presentation
      佐世保
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] WTAをターゲットとした、MRSA感染症の予防と治療

    • Author(s)
      黒川健児
    • Organizer
      長崎ビジネス交流会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] 微生物リガンドの同定によって垣間見る、細菌と自然免疫の攻防

    • Author(s)
      黒川健児、姫野勝
    • Organizer
      第26回微生物シンポジウム
    • Place of Presentation
      都市センターホテル(東京)
    • Year and Date
      2014-09-19 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] Novel staphylococcal wall teichoic acid (WTA)-derivative shows protective effects against USA300 MRSA infection in a murine model.

    • Author(s)
      Khan A, Lee MJ, Lee JH, Seong MY, Kurokawa K, Takahashi K, Ahn DH, Peschel A, and Lee BL.
    • Organizer
      The 16th International Symposium on Staphylococci and Staphylococcal Infections.
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2014-08-26 – 2014-08-29
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] 血清アミロイドP成分はペプチドグリカンを認識し、Fc受容体依存に黄色ブドウ球菌の貪食を誘導する

    • Author(s)
      黒川健児、安張鉉、鄭東俊、藤本ゆかり、深瀬浩一、姫野勝、李福律
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      佐世保
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] 免疫療法による、MRSA感染症の予防と治療法の開発

    • Author(s)
      黒川健児
    • Organizer
      第14回長崎国際大学 学術研究報告会
    • Place of Presentation
      佐世保
    • Data Source
      KAKENHI-PROJECT-25893286
  • [Presentation] Glycoepitopes of staphylococcal wall teichoic acid govern complement-mediated opsonophagocytosis via mannose-binding lectin and human serum antibody.

    • Author(s)
      Kurokawa K, Matsushita M, Takahashi K, Park HJ and Lee BL
    • Organizer
      The 16th International Symposium on Staphylococci and Staphylococcal Infections.
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2014-08-26 – 2014-08-29
    • Data Source
      KAKENHI-PROJECT-25893286
  • 1.  MURATA Takashi (30295521)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  KOBAYASHI Nobuyuki (30150329)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  TAKAHASHI Kazue
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  LEE Bok LEUL
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 5.  WATANABE Ken (00346909)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  UCHIYAMA JUMPEI (20574619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  MATSUZAKI Shigenobu (00190439)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  MIYAZAKI Naoyuki (00634677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MURATA Kazuyoshi (20311201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  関水 和久 (90126095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  伊藤 貴浩 (00323452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  秋光 信佳 (40294962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  UCHIYAMA Iyo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  SAKAGUCHI Yoshihiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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