ISHIDA Fumihiro 石田文宏

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Ishida Fumihiro 石田文宏

ISHIDA FUMIHIRO 石田文宏

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Researcher Number	80311695
Other IDs
Affiliation (Current)	2025: 信州大学, 学術研究院保健学系, 教授
Affiliation (based on the past Project Information) *help	2025: 信州大学, 学術研究院保健学系, 教授 2019 – 2022: 信州大学, 学術研究院保健学系, 教授 2015 – 2017: 信州大学, 学術研究院保健学系, 教授
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Medical sociology
Keywords	Principal Investigator 遺伝子変異 / T cell / pure red cell aplasia / bone marrow failure / 体細胞変異 / 骨髄不全症候群 / エピゲノム修飾 / T細胞 / STAT3 / クローン性造血 … More / 貧血 / 赤芽球癆 / 悪性リンパ腫 / 遺伝子異常 / NK細胞 / JAK/STAT系 / NK細胞白血病 / 分子標的 / NK細胞腫瘍 / JAK-STAT系 … More Except Principal Investigator 標的治療 / ゲノム編集 / 機能解析 / 遺伝子変異 / 免疫抑制療法 / 体細胞変異 / 骨髄系腫瘍関連遺伝子 / 再発・難治性 / 後天性赤芽球癆 / 医学教育 / eラーニング / team-based learning / problem-based learning / ブレンド型学習 Less

リンパ性クローン性造血の関与する血液異常の研究Principal Investigator
- Principal Investigator
  
  石田文宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Shinshu University
Mutational profiles of T cells in bone marrro failure syndrome as clinical markersPrincipal Investigator
- Principal Investigator
  
  Ishida Fumihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Shinshu University
後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発
- Principal Investigator
  
  廣川誠
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Akita University
Genetic alterations of aggressive NK cell leukemia and identification of molecular target candidatesPrincipal Investigator
- Principal Investigator
  
  ISHIDA FUMIHIRO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Shinshu University
blended PBL for clinical clerkship reform
- Principal Investigator
  
  Shimizu Ikuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical sociology
- Research Institution
  Shinshu University

All 2022 2021 2020 2019 2018 2016

All Journal Article Presentation

[Journal Article] Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia2022
- Author(s)
  Kelkka Tiina、Tyster Mikko、Lundgren Sofie、Feng Xingmin、Kerr Cassandra、Hosokawa Kohei、Huuhtanen Jani、Keranen Mikko、Patel Bhavisha、Kawakami Toruら
- Journal Title
  
  Leukemia
  
  Volume: 36 Issue: 9 Pages: 2317-2327
- DOI
  10.1038/s41375-022-01654-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16302, KAKENHI-PROJECT-22H00455, KAKENHI-PROJECT-20K08709
[Journal Article] Somatic mutations in acquired pure red cell aplasia2022
- Author(s)
  Kawakami Toru、Nakazawa Hideyuki、Ishida Fumihiro
- Journal Title
  
  Seminars in Hematology
  
  Volume: 59 Issue: 3 Pages: 131-136
- DOI
  10.1053/j.seminhematol.2022.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16302, KAKENHI-PROJECT-20K08709
[Journal Article] Incidence of Acquired Pure Red Cell Aplasia: A Nationwide Epidemiologic Analysis with Two Registry Databases in Japan.2022
- Author(s)
  Nakazawa H, Sakai K, Ohta A, Fujishima N, Matsuda A, Hosokawa K, Nakamura F, Nakao S, Mitani K, Ishida F
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 24 Pages: 6282-6290
- DOI
  10.1182/bloodadvances.2021006486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08709
[Journal Article] T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia2022
- Author(s)
  Kawakami Fumihiro、Kawakami Toru、Yamane Taku、Maruyama Masae、Kobayashi Jun、Nishina Sayaka、Sakai Hitoshi、Higuchi Yumiko、Hamanaka Kazutoshi、Hirokawa Makoto、Nakao Shinji、Nakazawa Hideyuki、Ishida Fumihiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: ー Issue: 6 Pages: 816-825
- DOI
  10.1007/s12185-022-03310-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16302, KAKENHI-PROJECT-20K08709
[Journal Article] Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia2022
- Author(s)
  Bhattacharya D, Teramo A, Gasparini VR, Huuhtanen J, Kim D, Theodoropoulos J, Schiavoni G, Barila G, Vicenzetto C, Calabretto G, Facco M, Kawakami T, Nakazawa H, Falini B, Tiacci E, Ishida F, Semenzato G, Kelkka T, Zambello R, Mustjoki S
- Journal Title
  
  Blood Cancer J
  
  Volume: 12 Issue: 2 Pages: 31-31
- DOI
  10.1038/s41408-022-00630-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08709, KAKENHI-PROJECT-21K16302
[Journal Article] Clonal hematopoiesis in adult pure red cell aplasia2021
- Author(s)
  Fujishima N、Kohmaru J、Koyota S、Kuba K、Saga T、Omokawa A、Moritoki Y、Ueki S、Ishida F、Nakao S、Matsuda A、Ohta A、Tohyama K、Yamasaki H、Usuki K、Nakashima Y、Sato S、Miyazaki Y、Nannya Y、Ogawa S、Sawada K、Mitani K、Hirokawa M
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 2253-2253
- DOI
  10.1038/s41598-021-81890-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08709, KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-19K08822
[Journal Article] Serum sphiongomyelin species profile is altered in hematological malignancies.2021
- Author(s)
  Hori A, Ishida F, Nakazawa H, Yamaura M, Morita S, Uehara T, Honda T, Hidaka H.
- Journal Title
  
  Clinica Chimica Acta.
  
  Volume: 514 Pages: 29-33
- DOI
  10.1016/j.cca.2020.11.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08709
[Journal Article] 後天性赤芽球癆の病態と治療研究の進歩2020
- Author(s)
  石田文宏
- Journal Title
  
  臨床血液
  
  Volume: 61 Pages: 92-98
- NAID
  130007937115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08709
[Journal Article] High frequency of STAT3 gene mutations in T‐cell receptor (TCR)γδ‐type T‐cell large granular lymphocytic leukaemia: implications for molecular diagnostics2020
- Author(s)
  Yamane T、Kawakami T、Sekiguchi N、Kobayashi J、Ueki T、Kobayashi H、Kawakami F、Nishina S、Sakai H、Oshimi K、Higuchi Y、Nakazawa H、Ishida F
- Journal Title
  
  British Journal of Haematology
  
  Volume: 190 Issue: 5 Pages: 46-51
- DOI
  10.1111/bjh.16820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08709
[Journal Article] T(o) be, or (not) to B, or both? Somatically mutated clonal T cells in common variable immunodeficiency and related immunodeficiencies2020
- Author(s)
  Ishida F、Nakazawa H
- Journal Title
  
  Haematologica
  
  Volume: 105 Issue: 12 Pages: 2702-2703
- DOI
  10.3324/haematol.2020.261982
- Open Access
- Data Source
  KAKENHI-PROJECT-20K08709
[Journal Article] Primary thyroid T‐cell lymphoma with leukemic manifestation2020
- Author(s)
  Kawakami T、Nakazawa H、Ishida F
- Journal Title
  
  eJHaem
  
  Volume: 1 Issue: 1 Pages: 18-18
- DOI
  10.1002/jha2.31
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08709
[Journal Article] Allogeneic stem cell transplantation for patients with aggressive NK-cell leukemia2020
- Author(s)
  Fujimoto A、Ishida F、Izutsu K、Yamasaki S、Chihara D、Suzumiya J、Mitsui T、Doki N、Sakai H、Kobayashi H、Kanda J、Fukuda T、Atsuta Y、Suzuki R
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 56 Issue: 2 Pages: 347-356
- DOI
  10.1038/s41409-020-01009-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08709
[Journal Article] Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in natural killer-cell malignancies2018
- Author(s)
  Dufva O, Kankainen M, Kelkka T, Sekiguchi N, Awad S, Eldfors S, Yadav B, Kuusanmaki H, Malani D, Andersson E, Pietarinen P, Saikko L, Kovanen P, Ojala T, Lee D, Loughran TJr., Nakazawa H, Suzumiya J, Suzuki R, Ko YH, Kim W, Chuang SS, Aittokallio T, Chan WC, Ohshima K, Ishida F, Mustjoki S
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1
- DOI
  10.1038/s41467-018-03987-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09471
[Journal Article] High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia.2016
- Author(s)
  Andersson E, Tanahashi T, Sekiguchi N, Gasparini VR, Bortoluzzi S, Kawakami T, Matsuda K, Mitsui T, Eldfors S, Bortoluzzi S, Coppe A, Binatti A, Lagstrom S,Ellonen P, Fukushima N, Nishina S, Senoo N, Sakai H, Nakazawa H, Kwong YL, Loughran TP, Maciejewski JP, Mustjoki S, Ishida F.
- Journal Title
  
  Blood
  
  Volume: 128 Issue: 20 Pages: 2465-2468
- DOI
  10.1182/blood-2016-06-724856
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461454, KAKENHI-PROJECT-15K09471
[Journal Article] Cell size variations of large granular lymphocyte leukemia; Implication of a small cell subtype of granular lymphocyte leukemia with STAT3 mutations.2016
- Author(s)
  Tanahashi T, Sekiguchi N, Matsuda K, Takezawa Y, Ito T, Kobayashi H, Ichikawa N, Nishina S, Senoo N, Sakai H, Nakazawa H, Ishida F.
- Journal Title
  
  Leukemia Res
  
  Volume: 45 Pages: 8-13
- DOI
  10.1016/j.leukres.2016.04.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09471
[Presentation] Molecular mechanisms of acquired pure red cell aplasia.2022
- Author(s)
  石田文宏
- Organizer
  第84回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] Mutational profiles of STAT3 and clonal hematopoiesis-related genes characteristic of acquired PRCA2022
- Author(s)
  川上徹、山根拓、川上史裕、丸山正恵、井田夏実、水野裕雅、朝倉亜美、仁科さやか、酒井均、樋口由美子、中澤英之、石田文宏
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] Clinical and pathophysiological features of acquired pure red cell aplasia2021
- Author(s)
  Fumihiro Ishida
- Organizer
  第83回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] Clonal T cells and STAT3 mutations in acquired pure red cell aplasia2020
- Author(s)
  Kawakami F, Kawakami T, Yamane T, Kobayashi J, Nishina S, Sakai H, Higuchi Y, Nakao S, Hirokawa M, Nakazawa H, Ishida F
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] Specific immunophenotype of CD8+T cells in patients with refractory pure red cell aplasia2020
- Author(s)
  Kawakami T, Yamane T, Kawakami F, Kobayashi J, Sekiguchi N, Nishina S, Sakai H, Higuchi Y, Nakazawa H, Ishida F
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] T-gamma/delta large granular lymphocyte leukemia identified a subset of patients with more symptomatic disease: Analysis of a collaborative international cohort of 130 patients2020
- Author(s)
  Barila G, Teramo A, Cheson H, Calabretto G, Chahal J, Vienzetto C, Almeida J, Shemo B, Min S, Gasparini VR, Pavan L, Oshimi K, Sokol L, Ishida F, Lamy T, Orfao A, Morice WG, Loughran T, Semenzato G, Zambello R.
- Organizer
  25th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] CD5 down-regulation unique to STAT3-mutated CD8+T cells in PRCA patients associated with T-LGLL.2020
- Author(s)
  Tanabe M, Hosokawa K, Imi T, Nakagawa N, Kawakami T, Ishida F, Nakazawa H, Nakao S.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] Recent　progress　in the diagnosis and management of acquired pure red cell aplasia.2020
- Author(s)
  Ishida F
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08709
[Presentation] 後天性赤芽球癆における骨髄性腫瘍関連遺伝子の体細胞変異に関する研究（PRCA-NGS2017）2019
- Author(s)
  幸丸純貴,小代田宗一,久場敬二,藤島直仁,嵯峨知生,面川　歩,植木重治,石田文宏,中尾眞二,松田　晃,太田晶子,通山　薫,鈴木隆二,三谷絹子,廣川　誠
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08856
[Presentation] Mutational Landscape of Aggressive Natural Killer Cell Leukemia and Drug Sensitivity Profiling Reveal Therapeutic Options in Natural Killer Cell Malignancies2016
- Author(s)
  Dufva O, Kankainen K, Kelkka T, Awad SA, Sekiguchi N, Yadav B, Eldfors S, Kuusanm H, Andersson EI, Malani D, Pietarinen P, Saikko L, Kovanen PE, Suzumiya J, Suzuki R, Ko YH, Kim WS, Chuang SS, Loughran TPJr, Chan WC, Ohshima K, Aittokallio T, Ishida F, Mustjoki S
- Organizer
  58th American Society of Hematology Annual Meeting & Exposition
- Place of Presentation
  米国サンディエゴ市
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15K09471

1. SEKIGUCHI Nodoka (80720953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. OHSHIMA Koichi (50203766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. SUZUMIYA Junji (70206556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. Shimizu Ikuo (60716231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Kikukawa Makoto (60378205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 廣川誠 (50241667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 久場敬司 (10451915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 小松久美 (70646554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MUSTJOKI Satu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. KIM Wong Seog

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. FUKUSHIMA Noriyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 川上徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

ISHIDA Fumihiro 石田 文宏

Ishida Fumihiro 石田 文宏

ISHIDA FUMIHIRO 石田 文宏

Research Projects

Research Products

Co-Researchers

リンパ性クローン性造血の関与する血液異常の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mutational profiles of T cells in bone marrro failure syndrome as clinical markersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic alterations of aggressive NK cell leukemia and identification of molecular target candidatesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

blended PBL for clinical clerkship reform

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Somatic mutations in acquired pure red cell aplasia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Incidence of Acquired Pure Red Cell Aplasia: A Nationwide Epidemiologic Analysis with Two Registry Databases in Japan.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clonal hematopoiesis in adult pure red cell aplasia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum sphiongomyelin species profile is altered in hematological malignancies.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 後天性赤芽球癆の病態と治療研究の進歩2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] High frequency of STAT3 gene mutations in T‐cell receptor (TCR)γδ‐type T‐cell large granular lymphocytic leukaemia: implications for molecular diagnostics2020

Author(s)

Journal Title

DOI

ISHIDA Fumihiro 石田文宏

Ishida Fumihiro 石田文宏

ISHIDA FUMIHIRO 石田文宏

[Presentation] Recent　progress　in the diagnosis and management of acquired pure red cell aplasia.2020