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NAKANISHI Hiroyuki  中西 宏之

ORCIDConnect your ORCID iD *help
Researcher Number 80314318
Other IDs
Affiliation (based on the past Project Information) *help 2023: 甲南女子大学, 医療栄養学部, 客員研究員
2022: 甲南女子大学, 医療栄養学部, 教授
2019 – 2021: 熊本大学, 大学院生命科学研究部(医), 教授
2009: Kumamoto University, 大学院・生命科学研究部, 教授
2007 – 2008: Kumamoto University, 大学院・医学薬学研究部, 教授 … More
2005 – 2006: 熊本大学, 大学院医学薬学研究部, 教授
2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 教授
2002 – 2004: 熊本大学, 医学部, 教授
2000 – 2002: 大阪大学, 医学系研究科, 助教授
2001: 大阪大学, 医学研究科, 助教授
1999: 大阪大学, 医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Basic Section 44010:Cell biology-related / General medical chemistry / Functional biochemistry
Except Principal Investigator
Biological Sciences / General medical chemistry
Keywords
Principal Investigator
エンドサイトーシス / ユビキチン / クラスリン / 細胞膜 / 中心体 / 細胞運動 / リン脂質 / 微小管結合タンパク質 / チュブリン / 微小管 … More / 細胞膜曲率 / BAR/F-BARドメイン / ユビキチン化 / 曲率 / Nedd4ファミリー / 細胞膜湾曲 / Nedd4ファミリー / BARドメイン / FCHO2 / floor plate / commissural axons / adherens Junctions / epithelial cells / cadherin / afadin / nectin / cell-cell adhesion / タイト・ジャンクション / ドミナント・ネガティブ変異体 / フロアープレート / 交連性ニューロン / アドヘレンス・ジャンクション / 上皮細胞 / カドヘリン / アファディン / ネクチン / 細胞間接着 / Rac small G protein / Cdc42 small G protein / frabin / JAM-ZO-l system / cadherin-catenin system / nectin-afadin system / cell motility / cell adhesion / ZO-1 / Nectin-Afadin-Ponsin系 / F-アクチン結合蛋白質 / Rac低分子量G蛋白質 / Cdc42低分子量G蛋白質 / Frabin / JAM-ZO-1系 / Cadherin-Catenin系 / Nectin-Afadin系 / 細胞接着 / 一次線毛 / 細胞膜変形 / 初期エンドソーム / 微小管結合蛋白質 / ソーティング / 線毛 / ユビキンチン化酵素E3 / インテグリン / ユビキチン化酵素E3 / リポソーム / 上皮性ナトリウムチャンネル / ラッフル膜 … More
Except Principal Investigator
細胞接着 / Frabin / BNI1 / Rabphilin-11 / Rabphilin-3A / Rab3A / Rab / Rho / 細胞骨格 / Actin / Microtubules / Cell adhesion / Transporter / Channel / Epithelial cells / 受容体 / 神経シナプス / 細胞膜裏打ち蛋白質 / 細胞間結合 / イオンチャンネル / PDZ領域 / 上皮細胞間結合 / ベクトル輸送 / 細胞間基質 / 肺胞上皮細胞 / 糸球体 / 細胞極性 / 微小管 / トランスポーター / チャネル / 上皮細胞 / Small G Protein / ROCK / mDia / SPA2 / SHP-2 / RabGD1 / BNT1 / 低分子量G蛋白質 / MARK / 増殖シグナル / 裏打ち蛋白質 / 足場依存性 / ビンキュリン / ビネキシン / アクチン / 細胞密着 / Frabin-Cdc42系 / Nectin-Afadin-Ponsin系 / Rab11 / Gab-1 / Frabin-Cdc42 / Nectin-Afadin / Cadherin-Catenin系 / Nectin-Afadin系 / がん / Necl-5 / Rac / Cdc42 / ネクチン / 細胞運動 / 細胞増殖 Less
  • Research Projects

    (9 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (20 People)
  •  細胞膜湾曲作用をもつ分子FCHO2によるエンドサイトーシスの制御機構Principal Investigator

    • Principal Investigator
      中西 宏之
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Konan Women's University
      Kumamoto University
  •  細胞骨格制御とがんの浸潤・転移の分子機構Principal Investigator

    • Principal Investigator
      中西 宏之
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Interactions of transportsome and cytoskeletonPrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroyuki
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Mechanisms of formation of cell-cell junctionsPrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kumamoto University
  •  細胞膜裏打ち蛋白質による足場依存的細胞増殖と浸潤の制御

    • Principal Investigator
      木岡 紀幸
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  細胞増殖のシグナリング機構

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Molecular links between vector transport machinery and cell adhesion machinery

    • Principal Investigator
      HATA Yutaka
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Functions and mode of action of novel regulatory systems for cell adhesion and motilityPrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Osaka University
  •  Modes of activation and action of Small G proteins

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University

All 2022 2008 2007 2004 2003

All Journal Article

  • [Journal Article] Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells2022

    • Author(s)
      Kikuchi K, sakamoto S, Uezu A, Yamamoto H, Ishiguro K, Shimamura K, Saito T, Hisanaga S, Nakanishi H
    • Journal Title

      Life Science Alliance

      Volume: 5(8) Issue: 8 Pages: e202201390-e202201390

    • DOI

      10.26508/lsa.202201390

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06643, KAKENHI-PROJECT-21K06190, KAKENHI-PROJECT-22K06226, KAKENHI-PROJECT-19K06544, KAKENHI-PROJECT-19K06664, KAKENHI-PROJECT-19K06942
  • [Journal Article] Mass spectrometric analysis of microtubule-cosedimented proteins from rat brain.2008

    • Author(s)
      Sakamoto, T., Uezu, A., Kawauchi, S., Kuramoto, T., Makino, K., Umeda, K., Araki, N., Baba, H., Nakanishi, H.
    • Journal Title

      Genes Cells 13

      Pages: 295-312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081014
  • [Journal Article] Identification and characterization of the novel centrosomal protein centlein. Biochem.2008

    • Author(s)
      Makino, K., Umeda, K., Uezu, A., Hiragami, Y., Sakamoto, T., Ihn, H., Nakanishi, H.
    • Journal Title

      Biophys. Res. Commun. 366

      Pages: 958-962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081014
  • [Journal Article] Frabin and its related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membrane.2008

    • Author(s)
      Nakanishi, H., Takai, Y.
    • Journal Title

      J. Cell. Mol. Med 12

      Pages: 1160-1176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081014
  • [Journal Article] Frabin and its related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membrane2008

    • Author(s)
      H. Nakanishi and Y. Takai
    • Journal Title

      J.Cell.Mol.Med 12

      Pages: 1119-1176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081014
  • [Journal Article] SGIP1・is an endocytic protein that directly interacts with phospholipids and Eps15.2007

    • Author(s)
      Uezu, A., Horiuchi, A., Kanda, K., Kikuchi, N., Umeda, K., Tsujita, K., Suetsugu, S., Araki, N., Yamamoto, H., Takenawa, H., Nakanishi, H.
    • Journal Title

      J. Biol. Chem 282

      Pages: 26481-26489

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081014
  • [Journal Article] Roles of nectins in cell adhesion, migration, and polization.2004

    • Author(s)
      Nakanishi, H., Takai, Y.
    • Journal Title

      Biol.Chem. 385

      Pages: 885-892

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] Roles of nectins in cell adhesion, migration and polarization.2004

    • Author(s)
      Nakanishi H, Takai Y
    • Journal Title

      Biol Chem 385

      Pages: 885-892

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144203
  • [Journal Article] Role of nectins in cell adhesion, migration and polarization.2004

    • Author(s)
      Nakanishi, H.
    • Journal Title

      Biological Chem. 385・10

      Pages: 885-892

    • Data Source
      KAKENHI-PROJECT-12215079
  • [Journal Article] Roles of nectins in cell adhesion, migration, and polization.2004

    • Author(s)
      Nakanishi, H
    • Journal Title

      Biol.Chem. 385

      Pages: 885-892

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] Contacts between the commissural axons and the floor plate cells are mediated by nectins.2004

    • Author(s)
      Okabe, N., Shimizu, K., Ozaki-Kuroda, K., Nakanishi, H., Morimoto, K., Takeuchi, M., Katsumaru, H., Murakami, F., Takai, Y.
    • Journal Title

      Dev.Biol. 273

      Pages: 244-256

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] Roles of nectins in cell adhesion, migration and polarization.2004

    • Author(s)
      Nakanishi H et al.
    • Journal Title

      Biol Chem 385

      Pages: 885-892

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144203
  • [Journal Article] Expression patterns of nectins and afadin uring epithelial remodeling in the mouse embryo.2004

    • Author(s)
      Okabe, N., Ozaki-Kuroda, K., Nakanishi, H., Shimizu, K., Takai, Y.
    • Journal Title

      Dev.Dyn. 230

      Pages: 174-186

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] Roles of nectins in cell adhesion, migration, and polization.2004

    • Author(s)
      Nakanishi, H.
    • Journal Title

      Biol.Chem. 385

      Pages: 885-892

    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] The expression of nectin-1a in normal human skin and various skin tumors.2003

    • Author(s)
      Matsushima, H., Utani, A., Endo, H., Matsuura, H., Kakuta, M., Nakamura, Y., Matsuyoshi, N., Matsui, C., Nakanishi, H., Takai, Y., Shinkai, H.
    • Journal Title

      Eur.J.Dermatol. 148

      Pages: 755-762

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] A novel rabconnectin-binding protein that directly binds a GDP/GTP exchange protein for the Rab3A small G protein implicated in Ca^<2+>-dependent exocytosis of neurotransmitter.2003

    • Author(s)
      Kawabe, H., Sakisaka, T., Yasumi, M., Shingai, T., Izumi, G., Nagano, F., Deguchi-Tawarada, M., Takeuchi, M., Nakanishi, H., Takai, Y.
    • Journal Title

      Genes Cells 8

      Pages: 537-546

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes---Analysis with the N-cadherin dominant negative mutant.2003

    • Author(s)
      Tanaka, Y., Nakanishi, H., Kakunaga, S., Okabe, N., Kawakatsu, T., Shimizu, K., Takai, Y.
    • Journal Title

      Mol.Biol.Cell 14

      Pages: 1597-1609

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion.2003

    • Author(s)
      Honda, T., Shimizu, K., Kawakatsu, T., Yasumi, M., Shingai, T., Fukuhara, A., Inagaki, M., Ozaki-Kuroda, K., Irie, K., Nakanishi, H., Takai, Y.
    • Journal Title

      Genes Cells 8

      Pages: 51-63

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390099
  • [Journal Article] Nectin and afadin : novel organizers of intercellular junctions.2003

    • Author(s)
      Takai Y, Nakanishi H
    • Journal Title

      J Cell Sci 116(Ptl)

      Pages: 17-27

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144203
  • 1.  UEZU Akiyoshi (70363520)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 2.  TAKAI Yoshimi (60093514)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  SASAKI Takuya (40241278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  萬代 研二 (50322186)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  的崎 尚 (80252782)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  FUJITA Naoyuki (50403192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  UMEDA Kazuaki (80444876)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  SHIRATAKI Hiromichi (90249962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TANAKA Kazuma (60188290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  HATA Yutaka (80313237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  入江 賢児 (90232628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  匂坂 敏朗 (80359843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  池田 わたる (90362699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  扇田 久和 (50379236)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  清水 一也 (50335353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  三好 淳 (80166214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  木岡 紀幸 (90234179)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  松尾 道憲 (00335308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  NOVIEK Peter
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  HALL Alan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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