saeki kumiko 佐伯久美子

… Alternative Names

Saeki Kumiko 佐伯久美子

SAEKI Kumiko 佐伯久美子

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Researcher Number	80322717
Other IDs
External Links
Affiliation (Current)	2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 2018 – 2019: 国立研究開発法人国立国際医療研究センター, その他部局等, その他 2016 – 2017: 国立研究開発法人国立国際医療研究センター, 疾患制御部, 幹細胞試料開発研究室長 2012: 独立行政法人国立国際医療研究センター, 疾患制御研究部, 室長 2011 – 2012: 独立行政法人国立国際医療研究センター, 研究所・疾患制御研究部, 室長 … More 2010: 独立行政法人国立国際医療研究センター, 研究所疾患制御研究部, 室長 2004 – 2007: 国立国際医療センター(研究所), 血液疾患研究部, 室長 2005: Research Institute International Medical Center of Japan, Division of Hematopoietic Disorder, Department of Hematology, Division Chief, 血液疾患研究部・造血障害研究室, 室長 2004: 国立国際医療センター研究所, 血液疾患研究部, 室長 2003: Research Institute International Medical Center of Japan, Division of Hematopoietic Disorder, Department of Hematology, Division Chief, 血液疾患研究部・造血障害研究室, 室長 2000 – 2003: 国立国際医療センター, 研究所, 室長 Less
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54040:Metabolism and endocrinology-related / Hematology Except Principal Investigator Hematology / Medium-sized Section 90:Biomedical engineering and related fields / Nanomaterials chemistry
Keywords	Principal Investigator CREB / 褐色脂肪細胞 / poly A signal / Alu / CD11b / PU.1 / Pluripotent stem cells / GLUT4 / human ES cells / HPLC … More / glucose uptake / skeletal muscle cells / 活性化因子 / スクリーニング / BATokine / 高感度検出系 / 血清診断マーカー / ヒト褐色脂肪細胞 / 血清マーカー / 免疫沈降 / モノクローナル抗体 / ヒト胚性幹細胞 / 代謝 / 糖尿病 / 肥満 / CHIP assay / histone acetylation / leukemic cell / fusion message / primer walking / intron / exon / PCR / splicing / tricostatin A / 融合型メッセージ / Alu配列 / ChIP assay / ヒストンアセチル化 / ヒストンメチル化 / poly A付加シグナル / 白血病細胞 / 融合型message / cell growth / morphological maturation / respiratory burst / cell adhesion / retinoic acid / p67^<phox> / 蛋白メッセージ発現解離 / Cyclyn D3 / ラミン受容体 / ラミン / 細胞形態 / CRE / 細胞増殖 / 細胞形態変化 / 活性酸素産生能 / 細胞接着 / レチノイン酸 / マクロフージ / ヒトES細胞 / インターフェロン / マクロファージ / 血球貪食 / ヒトiPS細胞 / 継代可能性 / 胚様体 / 平面培養 / 無フィーダー培養 / VE-cadherin / 血管内皮細胞 / 胚性幹細胞 / カニクイザル / DNA結合ドメイン / 誘導的遺伝子発現システム / 遺伝子導入法 / 質量分析 / 翻訳伸長因子 / 酸性アミノ酸 / DNAドメイン / テトラペプチド / 遺伝子導入 / アポトーシス … More Except Principal Investigator 治療 / バイオイメージング / 近赤外光 / 血管 / 光合成細菌 / ナノチューブ / ナノバイオ / ナノチューブ・フラーレン / バイオ応用 / フラーレン。ナノチューブ・グラフェン / 血管外漏出性亢進 / 近赤外蛍光造影 / イメージング / 近赤外蛍光造影剤 / 褐色脂肪組織 / カーボンナノチューブ / 分化誘導 / 造血幹細胞 / ヒト万能細胞 / 発生・分化 / 再生医学 / 無フィーダー培養 / 血管内皮細胞 / 血液細胞 / CD34 / 胚様体 / フィーダー細胞 / 血球 / ES細胞 Less

Realtime observation and optical control of living microbial probes in blood vessels
- Principal Investigator
  
  都英次郎
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Japan Advanced Institute of Science and Technology
Characterization of a novel BATokine that enhances glucose uptake by skeletal muscle cellsPrincipal Investigator
- Principal Investigator
  
  佐伯久美子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Tokyo Medical and Dental University
Identification of the antigen molecule that is recognized by a human brown adipocyte-specific monoclonal antibodyPrincipal Investigator
- Principal Investigator
  
  Saeki Kumiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Tokyo Medical and Dental University
  National Center for Global Health and Medicine
Near infrared fluorescent imaging of brown adipose tissues with carbon nanotubes
- Principal Investigator
  
  Yudasaka Masako
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nanomaterials chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Mechanistic study for the hemophagocytosis-like condition during the induction of hematopoietic cells from human pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  SAEKI Kumiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Research Institute, International Medical Center of Japan
Induction of hematopoietic stem cells from human pluripotent stem cells
- Principal Investigator
  
  YUO Akira
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Research Institute, International Medical Center of Japan
霊長類ES細胞に由来する血管内皮細胞の増殖機構解析と造血機能評価Principal Investigator
- Principal Investigator
  
  佐伯久美子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Research Institute, International Medical Center of Japan
霊長類ES細胞からの無フィーダー、無血清培養における血液細胞分化システムの確立
- Principal Investigator
  
  YUO Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Research Institute, International Medical Center of Japan
Development of therapeutic agents for leukemia that are targeted to a novel message originated from CREB genePrincipal Investigator
- Principal Investigator
  
  SAEKI Kumiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  International Medical Center of Japan (Research Institute)
Molecular mechanisms of regulation of proliferation, differentiation and death of hematopietic cells by CREB/ATF family proteins : an application to molecular-targeted therapy of hematopoietic malignanciesPrincipal Investigator
- Principal Investigator
  
  SAEKI Kumiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  International Medical Center of Japan (Research Institute)
ヒト血液細胞におけるcAMP応答エレメント結合蛋白の役割Principal Investigator
- Principal Investigator
  
  佐伯久美子
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Research Institute, International Medical Center of Japan

[Book] 日経バイオテク、バイオイメージング最前線、「カーボンナノチューブで褐色脂肪を近赤外光撮影」　「2017
- Author(s)
  湯田坂雅子、佐伯久美子
- Total Pages
  4
- Publisher
  日経BP社
- Data Source
  KAKENHI-PROJECT-16H02085
[Journal Article] Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and Tumorigenesis2023
- Author(s)
  Inoue Takayuki、Fu Bin、Nishio Miwako、Tanaka Miyako、Kato Hisashi、Tanaka Masashi、Itoh Michiko、Yamakage Hajime、Ochi Kozue、Ito Ayaka、Shiraki Yukihiro、Saito Satoshi、Ihara Masafumi、Nishimura Hideo、Kawamoto Atsuhiko、Inoue Shian、Saeki Kumiko、Enomoto Atsushi、Suganami Takayoshi、Satoh-Asahara Noriko
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 2 Pages: 350-350
- DOI
  10.3390/nu15020350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08526, KAKENHI-PROJECT-21K08571, KAKENHI-PROJECT-22K07456, KAKENHI-PROJECT-22K08667, KAKENHI-PROJECT-22K11700, KAKENHI-PROJECT-22K11720, KAKENHI-PROJECT-22K19524, KAKENHI-PROJECT-22K19723, KAKENHI-PROJECT-21K17557, KAKENHI-PROJECT-19KK0249, KAKENHI-PUBLICLY-21H05625, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-21H02835, KAKENHI-PROJECT-19K07905, KAKENHI-PROJECT-19K07927, KAKENHI-PUBLICLY-22H04806
[Journal Article] Cold-induced Conversion of Connective Tissue Skeleton in Brown Adipose Tissues2021
- Author(s)
  Yudasaka M, Okamatsu-Ogura Y, Tanaka T, Saeki K, Kataura H.
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 54 Issue: 5 Pages: 131-141
- DOI
  10.1267/ahc.21-00030
- NAID
  130008112278
- ISSN
  0044-5991, 1347-5800
- Year and Date
  2021-10-29
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08533, KAKENHI-PROJECT-19H02539, KAKENHI-PROJECT-21K08571
[Journal Article] The Remaining Mysteries about Brown Adipose Tissues2020
- Author(s)
  Nishio Miwako、Saeki Kumiko
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 11 Pages: 2449-2449
- DOI
  10.3390/cells9112449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08533
[Journal Article] New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-62020
- Author(s)
  Oka Masako、Kobayashi Norihiko、Matsumura Kazunori、Nishio Miwako、Nakano Kenta、Okamura Tadashi、Okochi Hitoshi、Minamisawa Tamiko、Shiba Kiyotaka、Saeki Kumiko
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 6 Pages: 1365-1365
- DOI
  10.3390/cells9061365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08533
[Journal Article] Exogenous Cytokine-Free Differentiation of Human Pluripotent Stem Cells into Classical Brown Adipocytes.2019
- Author(s)
  Oka M, Kobayashi N, Matsumura K, Nishio M, Saeki K.
- Journal Title
  
  Cells
  
  Volume: ８ Issue: 4 Pages: 373-373
- DOI
  10.3390/cells8040373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08533, KAKENHI-PROJECT-17K15781
[Journal Article] Fasting-dependent Vascular Permeability Enhancement in Brown Adipose Tissues Evidenced by Using Carbon Nanotubes as Fluorescent Probes.2018
- Author(s)
  Yudasaka M, Yomogida Y, Zhang M, Nakahara M, Kobayashi N, Tanaka T, Okamatsu-Ogura Y, Saeki K, Kataura H.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 14446-14446
- DOI
  10.1038/s41598-018-32758-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08118, KAKENHI-PROJECT-18K08533, KAKENHI-PROJECT-17H02742, KAKENHI-PROJECT-16H02085
[Journal Article] "Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat2017
- Author(s)
  Masako Yudasaka, Yohei Yomogida, Minfang Zhang, Takeshi Tanaka, Masako Nakahara, Norihiko Kobayashi, Yuko Okamatsu-Ogura, Ken Machida, Kazuhiko Ishihara, Kumiko Saeki, Hiromichi Kataura
- Journal Title
  
  Scientfic Reports
  
  Volume: 7 Issue: 1 Pages: 44760-44760
- DOI
  10.1038/srep44760
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220602, KAKENHI-PROJECT-16H02085, KAKENHI-PROJECT-16H07103, KAKENHI-PROJECT-25390024
[Journal Article] Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer.2012
- Author(s)
  M Nishio, T Yoneshiro, M Nakahara, S Suzuki, K Saeki, M Hasegawa, Y Kawai, H Akutsu, A
- Journal Title
  
  Cell Metabolism
  
  Volume: 16 Issue: 3 Pages: 394-406
- DOI
  10.1016/j.cmet.2012.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02798, KAKENHI-PROJECT-22591053
[Journal Article] Early senescence is not an inevitable fate of human induced pluripotent stem-derived cells2011
- Author(s)
  Gokoh M, Nakamura N, Matsuyama S, Nishio M, Akutsu H, Umezawa A, Yasuda K, Yuo A, Saeki K
- Journal Title
  
  Cellular Reprogram
  
  Volume: 13 Issue: 4 Pages: 361-370
- DOI
  10.1089/cell.2011.0004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591255, KAKENHI-PROJECT-22390312, KAKENHI-PROJECT-22591053
[Journal Article] ヒトES細胞からの造血細胞への分化-好中球産生を中心として-2009
- Author(s)
  佐伯久美子、湯尾明
- Journal Title
  
  医学のあゆみ 229
  
  Pages: 704-710
- Data Source
  KAKENHI-PROJECT-21591255
[Journal Article] The protein expression profile of cynomolgus monkey embryonicstem cells in two-dimensional gel electrophoresis:a successful identification of multiple proteins using human databases.2007
- Author(s)
  Nakahara M, Saeki K, Yogiashi Y, Kimura A, Horiuchi A, Nakamura N, Yoneda A, Saeki K, Matsuyama S, Nakamura M, Toda T, Kondo Y, Kaburagi Y, Yuo A
- Journal Title
  
  Journal of Electrophoresis 51
  
  Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659288
[Journal Article] The protein expression profile of cynomolus monkey embryonic stem cells in two-dimensional electrophoresis : a successful identifyication of multiple proteins using human databases2007
- Author(s)
  Nakahara M, Saeki K, Yogiashi Y, Kimura A, Horiuchi A, Nakamura N, Yoneda A, Saeki K, Matsuyama S, Nakamura M, Toda T, Kondo Y, Kaburagi Y, You A
- Journal Title
  
  Journal of Electrophoresis 51
  
  Pages: 1-8
- Data Source
  KAKENHI-PROJECT-18659288
[Journal Article] Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells.2006
- Author(s)
  Yasugi E, Horiuchi A, Uemura I, Okuma E, Nakatsu M, Saeki K, Kamisaka Y, Kagechika H, Yasuda K, Yuo A
- Journal Title
  
  Development, Growth ＆ Differentiation 48
  
  Pages: 177-188
- Data Source
  KAKENHI-PROJECT-18659288
[Journal Article] Efficient and repetitive production of hematopoietic and endothelial cells from feeder-free monolayer culture system of primate embryonic stem cells.2006
- Author(s)
  Zhang H, Saeki K, Kimura A, Saeki K, Nakahara M, Doshi M, Kondo Y, Nakano T, Yuo A.
- Journal Title
  
  Biology of Reproduction 74
  
  Pages: 295-306
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] Identification of human neutrophils during experimentally induced inflammation in mice with transplanted CD34+ cells from human umbilical cord blood.2006
- Author(s)
  Doshi M, Koyanagi M, Nakahara M, Saeki K, Saeki K, Yuo A
- Journal Title
  
  International Journal of Hematology 84
  
  Pages: 231-237
- NAID
  10018304001
- Data Source
  KAKENHI-PROJECT-18659288
[Journal Article] Synergistic effects of dehydro-epiandrosterone and retinoic acid on granulocytic differentiation of human promyelocytic NB4 cells.2005
- Author(s)
  Nakatsu M, Doshi M, Saeki K, Yuo A
- Journal Title
  
  Int J Hematol 81
  
  Pages: 32-38
- NAID
  10014282556
- Data Source
  KAKENHI-PROJECT-16659260
[Journal Article] A prostacyclin analog prevents radiocontrast nephropathy via phosphorylation of cyclic AMP response element binding protein.2005
- Author(s)
  Yano T, Itoh Y, Kubota T, Sendo T, Koyama T, Fujita T, Saeki K, Yuo A, Oishi R.
- Journal Title
  
  American Journal of Pathology 166
  
  Pages: 1333-1342
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] Proteomic analysis on insulin signaling in human hematopoietic cells : identification of CLIC1 and SRp20 as novel downstream effectors of insulin.2005
- Author(s)
  Saeki K, Yasugi E, Okuma E, Breit SN, Nakamura M, Toda T, Kaburagi Y, Yuo A
- Journal Title
  
  Am J Physiol Endocrinol Metab 289
- Data Source
  KAKENHI-PROJECT-16659260
[Journal Article] Proteomic analysis on insulin signaling in human hematopoietic cells : identification of CLIC1 and SRp20 as novel downstream effectors of insulin.2005
- Author(s)
  Saeki K, Yasugi E, Okuma E, Breit SN, Nakamura M, Toda T, Kaburagi Y, Yuo A
- Journal Title
  
  Am J Physiol Endocrinol Metab 289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] Synergistic effects of dehydroepiandrosterone and retinoic acid on granulocytic differentiation of human promyelocytic NB4 cells.2005
- Author(s)
  Nakatsu M, Doshi M, Saeki K, Yuo A
- Journal Title
  
  Int J Hematol 81
  
  Pages: 32-38
- NAID
  10014282556
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] Synergistic effects of dehydroepiandrosterone and retinoic acid on granulocytic differentiation of human promyelocytic NB4 cells2005
- Author(s)
  Nakatsu M, Doshi M, Saeki K, Yuo A
- Journal Title
  
  Int J Hematol 81
  
  Pages: 32-38
- NAID
  10014282556
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] Synergistic effects of dehydroepiandrosterone and retinoic acid on granulocytic differentiation of human promyelocytic NB4 cells.2005
- Author(s)
  Nakatsu M, Doshi M, Saeki K, Yuo A
- Journal Title
  
  Int J Hematol 81
  
  Pages: 32-38
- NAID
  10014282556
- Data Source
  KAKENHI-PROJECT-16659260
[Journal Article] Proteomic analysis on insulin signaling in human hematopoietic cells : identification of CLIC1 and SRp20 as novel downstream effectors of insulin2005
- Author(s)
  Saeki K, Yasugi E, Okuma E, Breit SN, Nakamura M, Toda T, Kaburagi Y, Yuo A
- Journal Title
  
  Am J Physiol Endocrinol Metab 289
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] Proteomic analysis on insulin signaling in human hematopoietic cells : identification of CLIC1 and SRp20 as novel downstream effectors of insulin.2005
- Author(s)
  Saeki K, Yasugi E, Okuma E, Breit SN, Nakamura M, Toda T, Kaburagi Y, Yuo A.
- Journal Title
  
  American Journal of Physiology, Endocrinology and Metabolism 289
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] A prostacyclin analog prevents radiocontrast nephropathy via phosphorylation of cyclic AMP response element binding protein.2005
- Author(s)
  Yano T, Itoh Y, Kubota T, Sendo T, Koyama T, Fujita T, Saeki K, Yuo A, Oishi R
- Journal Title
  
  Am J Pathol 166
  
  Pages: 1333-1342
- Data Source
  KAKENHI-PROJECT-16659260
[Journal Article] Synergistic effects of dehydroepiandrosterone and retinoic acid ongranulocytic differentiation of human promyelocytic NB4 cells.2005
- Author(s)
  Nakatsu M, Doshi M, Saeki K, Yuo A.
- Journal Title
  
  International Journal of Hematology 81
  
  Pages: 32-38
- Data Source
  KAKENHI-PROJECT-16590969
[Journal Article] Distinct involvement of cAMP-response element-dependent transcriptions in functional and morphological maturation during retinoid-mediated human myeloid differentiation2003
- Author(s)
  Saeki K, Saeki K, Yuo A
- Journal Title
  
  J Leukoc Biol 73
  
  Pages: 673-681
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Distinct involvement of cAMP-response element-dependent transcriptions in functional and morphological maturation during retinoid-mediated human myeloid differentiation.2003
- Author(s)
  Saeki K, Saeki K, Yuo A
- Journal Title
  
  J Leukoc Biol 73
  
  Pages: 673-681
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells.2003
- Author(s)
  Saeki K, Zhang H, Nakatsu M, Yoshimori T, Kabeya Y, Yamamoto A, Kaburagi Y, Yuo A
- Journal Title
  
  J Leukoc Biol 74
  
  Pages: 1108-1116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Granulocyte-macrophage colony-stimulating factor and interleukin 3 induce cell cycle progression through the synthesis of c-Myc protein by internal ribosome entry site-mediated translation via phosphatidylinositol 3-kinase pathway in human factor-dependent leukemic cells2003
- Author(s)
  Kobayashi N, Saeki K, Yuo A
- Journal Title
  
  Blood 102
  
  Pages: 3186-3195
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells2003
- Author(s)
  Saeki K, Zhang H, Nakatsu M, Yoshimori T, Kabeya Y, Yamamoto A, Kaburagi Y, Yuo A
- Journal Title
  
  J Leukoc Biol 74
  
  Pages: 1108-1116
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Granulocyte-macrophage colony-stimulating factor and interleukin 3 induce cell cycle progression through the synthesis of c-Myc protein by internal ribosome entry site-mediated translation via phosphatidylinositol 3-kinase pathway in human factor-dependent leukemic cells.2003
- Author(s)
  Kobayashi N, Saeki K, Yuo A
- Journal Title
  
  Blood 102
  
  Pages: 3186-3195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukemic cells stimulated by epigallocatechin-3-gallate (EGCG) : a distinct pathway from those of chemically-induced and receptor-mediated apoptosis.2002
- Author(s)
  Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Saeki K, Isemura M, Yuo A
- Journal Title
  
  Biochem J 368
  
  Pages: 705-720
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Potential roles of extracellular-signal regulated kinase (ERK) but not p38 during myeloid differentiation of U937 cells stimulated by cytokines : augmentation of differentiation via prolonged activation of ERK.2002
- Author(s)
  Okuma E, Inazawa Y, Saeki K, Yuo A
- Journal Title
  
  Exp Hematol 30
  
  Pages: 571-581
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukemic cells stimulated by epigallocatechin-3-gallate (EGCG) : a distinct pathway from those of chemically-induced and receptor-mediated apoptosis2002
- Author(s)
  Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Saeki K, Isemura M, Yuo A
- Journal Title
  
  Biochem J 368
  
  Pages: 705-720
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Journal Article] Potential roles of extracellular-signal regulated kinase (ERK) but not p38 during myeloid differentiation of U937 cells stimulated by cytokines : augmentation of differentiation via prolonged activation of ERK2002
- Author(s)
  Okuma E, Inazawa Y, Saeki K, Yuo A
- Journal Title
  
  Exp Hematol 30
  
  Pages: 571-581
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Patent] PLURIPOTENT STEM CELL-DERIVED BROWN ADIPOCYTES, PLURIPOTENT STEM CELL-DERIVED CELL AGGREGATE, METHOD FOR PRODUCING SAME, AND CELL THERAPY AND MEDICAL THERAPY THEREFOR2018
- Inventor(s)
  佐伯久美子、湯尾明、西尾美和子、川崎正子、佐伯晃一、長谷川護
- Industrial Property Rights Holder
  国立研究開発法人国立国際医療研究センター、株式会社IDファーマ
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18K08533
[Patent] 多能性幹細胞由来褐色脂肪細胞、多能性幹細胞由来細胞凝集物と、その製造方法及び細胞療法、内科療法2013
- Inventor(s)
  佐伯久美子、湯尾明、西尾美和子、川崎正子、佐伯晃一、長谷川護
- Industrial Property Rights Holder
  独立行政法人国立国際医療研究センター、ディナベック株式会社
- Filing Date
  2013-04-26
- Overseas
- Data Source
  KAKENHI-PROJECT-22591053
[Patent] 多能性幹細胞由来褐色脂肪細胞、多能性幹細胞由来細胞凝集物と、その製造方法及び細胞療法、内科療法2012
- Inventor(s)
  佐伯久美子、他
- Industrial Property Rights Holder
  独立行政法人国立国際医療研究センター、ディナベック株式会社
- Filing Date
  2012-04-26
- Overseas
- Data Source
  KAKENHI-PROJECT-22591053
[Patent] 霊長類動物胚性幹細胞の培養及び継代方法、並びにその分化誘導方法2012
- Inventor(s)
  湯尾明、佐伯久美子、佐伯晃一、中原正子、中村直子、過足芳子、松山さと子、米田麻子
- Industrial Property Rights Holder
  独立行政法人国立国際医療研究センター、田辺三菱製薬株式会社
- Acquisition Date
  2012-08-24
- Data Source
  KAKENHI-PROJECT-22591053
[Patent] 多能性幹細胞由来褐色脂肪細胞とその製造方法並びに細胞療法的使用2011
- Inventor(s)
  佐伯久美子、湯尾明、西尾美和子、川崎正子、佐伯晃一、長谷川護
- Industrial Property Rights Holder
  独立行政法人国立国際医療研究センター総長、ディナベック株式会社
- Industrial Property Number
  2011-100218
- Acquisition Date
  2011-04-27
- Data Source
  KAKENHI-PROJECT-21591255
[Patent] 霊長類動物胚性幹細胞の培養及び継代方法、並びにその分化誘導方法2007
- Inventor(s)
  湯尾明、佐伯久美子、佐伯晃一、中原正子、中村直子、過足芳子、松山さと子、米田麻子
- Industrial Property Rights Holder
  国立国際医療センター、田辺三菱製薬株式会社
- Filing Date
  2007-11-09
- Acquisition Date
  2007-11-09
- Overseas
- Data Source
  KAKENHI-PROJECT-18659288
[Patent] 霊長類動物胚性幹細胞の培養及び継代方法、並びにその分化誘導方法2006
- Inventor(s)
  湯尾明, 佐伯久美子, 佐伯晃一, 中原正子, 中村直子, 過足芳子, 松山さと子
- Industrial Property Rights Holder
  国立国際医療センター, 田辺製薬株式会社
- Industrial Property Number
  2006-303929
- Filing Date
  2006-11-09
- Data Source
  KAKENHI-PROJECT-18659288
[Patent] 急性白血病細胞死誘導体2003
- Inventor(s)
  佐伯久美子, 湯尾明, 中津雅美, 佐々木道夫
- Industrial Property Rights Holder
  佐伯久美子, 湯尾明, 中津雅美, 佐々木道夫
- Filing Date
  2003-09-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571008
[Presentation] ヒトiPS細胞由来褐色脂肪細胞の活性化作用因子スクリーニング系の開発2024
- Author(s)
  井上栞杏、小林久美子、工藤倫子、上畠さち、影山将克、佐伯久美子、西尾美和子
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K08571
[Presentation] ヒト褐色脂肪組織(BAT)におけるGDF15の発現～新たなバイオマーカーの可能性～2022
- Author(s)
  井上栞杏、副島友莉恵、佐伯久美子、沢辺元司、西尾美和子
- Organizer
  第16回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-21K08571
[Presentation] １型糖尿病モデルマウスを用いたタークペプチドの前臨床試験2020
- Author(s)
  佐伯　久美子
- Organizer
  サイエンスフォーラム2020オンライン－根治に向けてのカウントダウン 6 ―
- Invited
- Data Source
  KAKENHI-PROJECT-18K08533
[Presentation] A human brown adipocyte-specific monoclonal antibody for an evaluation of brown adipose tissue mass in humans2019
- Author(s)
  Masako Oka, Kazunori Matsumura, Kumiko Saeki
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K08533
[Presentation] カーボンナノチューブの近赤外発光を利用した褐色脂肪造影2018
- Author(s)
  湯田坂雅子、蓬田洋平、張民芳、田中丈士、中原正子、小林徳彦、岡松優子、町田拳、石原一彦、佐伯久美子、片浦弘道
- Organizer
  第34回DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02085
[Presentation] Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat2017
- Author(s)
  Masako Yudasaka, Yohei Yomogida, Minfang Zhang, Takeshi Tanaka, Masako Nakahara, Norihiko Kobayashi, Yuko Okamatsu-Ogura, Ken Machida, Kazuhiko Ishihara, Kumiko Saeki, Hiromichi Kataura
- Organizer
  第7回ナノカーボンバイオサテライト
- Data Source
  KAKENHI-PROJECT-16H02085
[Presentation] Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat2017
- Author(s)
  Masako Yudasaka, Yohei Yomogida, Minfang Zhang, Takeshi Tanaka, Masako Nakahara, Norihiko Kobayashi, Yuko Okamatsu-Ogura, Ken Machida, Kazuhiko Ishihara, Kumiko Saeki, Hiromichi Kataura
- Organizer
  フラーレン・ナノチューブ・グラフェン学会,第53回シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02085
[Presentation] Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat2017
- Author(s)
  Masako Yudasaka, Yohei Yomogida, Minfang Zhang, Takeshi Tanaka, Masako Nakahara, Norihiko Kobayashi, Yuko Okamatsu-Ogura, Ken Machida, Kazuhiko Ishihara, Kumiko Saeki, Hiromichi Kataura
- Organizer
  11th International Sympoisum of Nanomedicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02085
[Presentation] Brown adipocyte differentiation of human pluripotent stem cells without genetic manipulation.2012
- Author(s)
  Nishio M, Nakahara M, Saeki K, Hasegawa M, Yuo A, Saeki K
- Organizer
  The 10th Annual Meeting International Society of Stem Cell Research
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22591053
[Presentation] 無フィーダー・無血清環境でのヒトES細胞からの赤血球および造血ストロマ細胞の作製2011
- Author(s)
  西尾美和子、中村直子、松山さと子、湯尾明、佐伯久美子
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591255
[Presentation] Directed differentiation of human pluripotent stem cells into brown adipocyte-like cells2011
- Author(s)
  Nishio M, Nakahara M, Yuo A, Saeki K
- Organizer
  The 4th Annual Congress of Regenerative Medicine & Stem Cell
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21591255
[Presentation] 無フィーダー・無血清環境でのヒトES細胞からの赤血球および造血ストロマ細胞の作製2011
- Author(s)
  西尾美和子、中村直子、松山さと子、湯尾明、佐伯久美子
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591053
[Presentation] A feeder-free hematopoietic differentiation of human induced pluripotent stem cells : towards a provision of rejection-free neutrophils for granulocyte transfusion therapy2009
- Author(s)
  Saeki K, YUo A, 他
- Organizer
  7th annual meeting of International Society for Stem Cell Research
- Place of Presentation
  スペイン、バルセロナ
- Data Source
  KAKENHI-PROJECT-21591255
[Presentation] 霊長類(サル、ヒト)ES細胞からの無フィーダー培養による高効率な血管内皮細胞分化誘導法の開発-各サイトカインの役割の検討及びin vivoでの機能評価-。2007
- Author(s)
  中原正子、過足芳子、佐伯久美子、佐伯晃一、中村直子、松山さと子、米田麻子、小柳真、近藤靖、末盛博文、中辻憲夫、湯尾明
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18659288

1. YUO Akira (90221663)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. NISHIO Miwako (30623318)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. Yudasaka Masako (70159226)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 片浦弘道 (30194757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. 岡松優子 (90527178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 都英次郎 (70443231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田中丈士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 田中都

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

saeki kumiko 佐伯 久美子

Saeki Kumiko 佐伯 久美子

SAEKI Kumiko 佐伯 久美子

Research Projects

Research Products

Co-Researchers

Realtime observation and optical control of living microbial probes in blood vessels

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Characterization of a novel BATokine that enhances glucose uptake by skeletal muscle cellsPrincipal Investigator

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Identification of the antigen molecule that is recognized by a human brown adipocyte-specific monoclonal antibodyPrincipal Investigator

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Near infrared fluorescent imaging of brown adipose tissues with carbon nanotubes

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Mechanistic study for the hemophagocytosis-like condition during the induction of hematopoietic cells from human pluripotent stem cellsPrincipal Investigator

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Induction of hematopoietic stem cells from human pluripotent stem cells

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霊長類ES細胞に由来する血管内皮細胞の増殖機構解析と造血機能評価Principal Investigator

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霊長類ES細胞からの無フィーダー、無血清培養における血液細胞分化システムの確立

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Development of therapeutic agents for leukemia that are targeted to a novel message originated from CREB genePrincipal Investigator

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Molecular mechanisms of regulation of proliferation, differentiation and death of hematopietic cells by CREB/ATF family proteins : an application to molecular-targeted therapy of hematopoietic malignanciesPrincipal Investigator

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ヒト血液細胞におけるcAMP応答エレメント結合蛋白の役割Principal Investigator

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[Book] 日経バイオテク、バイオイメージング最前線、「カーボンナノチューブで褐色脂肪を近赤外光撮影」 「2017

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[Journal Article] Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and Tumorigenesis2023

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saeki kumiko 佐伯久美子

Saeki Kumiko 佐伯久美子

SAEKI Kumiko 佐伯久美子

[Book] 日経バイオテク、バイオイメージング最前線、「カーボンナノチューブで褐色脂肪を近赤外光撮影」　「2017