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Tomimoto Hidekazu  冨本 秀和

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TOMIMOTO Hidekazu  冨本 秀和

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Researcher Number 80324648
Other IDs
Affiliation (Current) 2025: 三重大学, 医学系研究科, 特定教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 三重大学, 医学系研究科, 特定教授
2016 – 2021: 三重大学, 医学系研究科, 教授
2017: 三重大学, 医学研究科, 教授
2012 – 2016: 三重大学, 医学(系)研究科(研究院), 教授
2014: 三重大学, 大学院医学系研究科, 教授 … More
2013: 三重大学, 大学院・医学系研究科・ 神経感覚医学講座神経病態内科学, 教授
2008 – 2013: Mie University, 大学院・医学系研究科, 教授
2012: 三重大学, 医学(系)医学科(研究院), 教授
2007: 京都大学, 医学研究所, 講師
2006 – 2007: Kyoto University, Graduate School of Medicine, senior assistant professor, 医学研究科, 講師
2002 – 2005: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related / Human pathology / Neurology / Neurology
Except Principal Investigator
Neurology / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene and public health / Hygiene / Basic Section 56010:Neurosurgery-related / Nerve anatomy/Neuropathology
Keywords
Principal Investigator
アミロイドβ / Lewy body / H5 / Septin / 血管周囲腔 / グリンパティック / アミロイド血管症 / アルツハイマー病 / 毛細血管 / 剖検脳 … More / 脳アミロイド血管症 / マイクロMRI / Glial cytoplasmic inclusion(GCI) / αsynuclein / Proteasome / Synphilin / 多系統萎縮症 / パーキンソン病 / ubiquitin / α-synuclein / sepin / 黒質 / glial cytoplasmic inclusion(GCI) / septin / glial cytoplasmic inclusion (GCI) / Lewy小体 / αシヌクレイン / プロテアゾーム / synphilin-1 / 血管内皮 / マウス / 慢性脳低灌流 / ES細胞 / VEGF / 線条体 / 大脳皮質 / 再生医療 / iPS細胞 / 血管新生 / 人工多能性幹細胞 / 胚性幹細胞 / 血管前駆細胞 / 慢性脳虚血 … More
Except Principal Investigator
アルツハイマー病 / バイオマーカー / 酸化ストレス / 認知症 / プロテオミクス / プロテオミクス解析 / 慢性脳低灌流 / 血液脳関門 / 血液バイオマーカー / エクソソーム / eIF2α / vanishing / GFAP / eIF2B / leukoencephalopathy / 脳神経疾患 / 早期診断法 / 血液 / プロテオーム / シロスタゾール / 血漿 / 酸化損傷タンパク質 / 二光子レーザー顕微鏡 / 筋萎縮性側索硬化症 / randomized study / cohort study / outcome improvement / prevention / subarachnoid hemorrhage / 若年性アルツハイマー病 / アルツハイマー型認知症 / アミロイドβ / 抗糖化 / 脳循環障害 / アミロイド / 抗糖化薬 / オリゴマー / 病理学 / 痴呆 / 脳・神経 / 神経科学 / 脳アミロイド血管症 / タウ / 抗糖化作用 / タキシフォリン / トランスジェニックマウス / 活性酸素 / 高齢化 / 抗酸化剤 / アセタゾラマイド / 二光子顕微鏡 / 代償性血管拡張 / 脳循環予備能 / 代償性脳循環調節機構 / 脳灌流圧低下 / matrix metalloproteinase(MMP) / subcortical vascular dementia / extracellular matrix / basement membrane / knockout mouse / blood-brain barrier / chronic cerebral hypoperfusion / white matter lesions / 慢性脳低灌流モデル / マウス / マトリックスメタロプロテァーゼ / マトリックスメタロプロテアーゼ / 皮質下血管性認知症 / 細胞外マトリックス / 基底膜 / ノックアウトマウス / 白質病変 / astrocyte / Binswanger disease / cerebral white matter / 大脳白質 / アストロサイト / Binswanger型白質脳症 / 大脳皮質 / 二次元電気泳動 / エキソソーム / タンパク質 / 老化 / 衛生 / 蛍光標識二次元ディファレンスゲル電気泳動法 / カルボニル化 / 脳脊髄液 / Tg-SwDIマウス / モデルマウス / 微小梗塞 / 医師主導治験 / 臨床試験 / βアミロイド / アミロイド血管症 / 活性酸素種 / 神経細胞死 / 黒質 / パーキンソン病 / Adhesion / Rolling / 白血球 / 脳血液関門 / 血管内皮細胞 / 二光子レーザー顕微 / 脳小血管病 / rolling and adhesion / capillary plugging / Two-photon microscopy / chronic cerebral hypoperfuion / small vessel disease / 神経分子病態学 / 西ニューギニア地域 / パーキンソン症候群 / 運動ニューロン疾患 / パーキンソン症候 / 神経変性疾 / DDS / アポトーシス / 脳虚血 / 神経病態薬理学 Less
  • Research Projects

    (19 results)
  • Research Products

    (153 results)
  • Co-Researchers

    (48 People)
  •  若年性アルツハイマー病の原因解明と早期血液バイオマーカーの探索

    • Principal Investigator
      及川 伸二
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Mie University
  •  A registry cohort study for prevention of subarachnoid hemorrhage and randomized controlled trial study of outcome improvement

    • Principal Investigator
      井川 房夫
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Shimane University
  •  A strategic research to establish blood biomarker for cerebral amyloid angiopathy and disease modifying therapy in dementia.Principal Investigator

    • Principal Investigator
      Tomimoto Hidekazu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Mie University
  •  Analysis of oxidatively damaged proteins in blood including exosomes in dementia and risk assessment for dementia

    • Principal Investigator
      Oikawa Shinji
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Mie University
  •  ex vivo imaging of cerebral amyloid angiopathy and its associated lesions using micro-MRIPrincipal Investigator

    • Principal Investigator
      Tomimoto Hidekazu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Mie University
  •  The compensatory micro circulation regulation mechanism against cerebral perfusion pressure decrease

    • Principal Investigator
      yata kenichiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Mie University
  •  Development of a PET imaging agent and disease biomarker for Alzheimer's disease.

    • Principal Investigator
      OIKAWA Shinji
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene and public health
    • Research Institution
      Mie University
  •  Development of anti-glycosylation agents for Alzheimer disease

    • Principal Investigator
      IHARA MASAFUMI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Proteomic profiling of exosomal proteins for the early diagnosis of Alzheimer's disease and prevention of Alzheimer's disease

    • Principal Investigator
      OIKAWA Shinji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene and public health
    • Research Institution
      Mie University
  •  A study on the pathogenic mechanism of amyotrophic lateral sclerosis (ALS) and search for efficient biomarkers using proteomic/metabolomic analysis

    • Principal Investigator
      OIKAWA Shinji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Mie University
  •  Development of risk assessment methods for parkinson's disease using carbonylated protein, a protein oxidation product, as a predictive indicator

    • Principal Investigator
      OIKAWA Shinji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Mie University
  •  Regenerative therapy for Alzheimer's disease and cerebral amyloid angiopathy

    • Principal Investigator
      IHARA Masafumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      National Cardiovascular Center Research Institute
      Foundation for Biomedical Research and Innovation
      Kyoto University
  •  Impairment of neurovasculaer unit under chronic hypoperfusion

    • Principal Investigator
      YATA Kenichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Mie University
  •  Longitudinal study for neuro-degenerative diseases in Papua, Indonesia

    • Principal Investigator
      OKUMIYA Kiyohito
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Research Institute for Humanity and Nature
  •  Transplantation of vascular progenitor cells derived from human ES cells in a mouse model of chronic cerebral hypoperfusionPrincipal Investigator

    • Principal Investigator
      TOMIMOTO Hidekazu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Mie University
  •  虚血巣特異的ドラッグ・デリバリーシステムの開発

    • Principal Investigator
      田中 智洋
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Kyoto University
  •  Pathogenesis of ischemic white matter lesions ; an analysis using a novel mouse model for vascular dementia.

    • Principal Investigator
      SAIKI Hidemoto
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tazuke Kofukai Medical Research Institute
  •  Molecular mechanism of the formation of the cerebral white matter lesion.

    • Principal Investigator
      MATSUI Masaru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kanazawa Medical University
  •  significance of septin in the formation of inclusion bodies in neurodegenerative disorders.Principal Investigator

    • Principal Investigator
      TOMIMOTO Hidekazu
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kyoto University

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All Journal Article Presentation Book Patent

  • [Book] 認知症イメージングテキスト2018

    • Author(s)
      冨本 秀和
    • Total Pages
      15
    • Publisher
      医学書院
    • ISBN
      9784260032315
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Book] 慢性脳低灌流モデル.北徹, 堀内久徳, 柳田素子, 猪原匡史, 冨本秀和, 並河徹編「モデル動物利用マニュアル. 疾患モデルの作製と利用-循環器疾患」(株)

    • Author(s)
      猪原匡史, 冨本秀和
    • Total Pages
      486
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Cerebral Microbleeds With Atrial Fibrillation After Ablation Therapy2022

    • Author(s)
      Hirata Yoshinori、Kato Natsuko、Muraga Kanako、Shindo Akihiro、Nakamura Naoko、Matsuura Keita、Ii Yuichiro、Shiga Mariko、Tabei Ken-ichi、Satoh Masayuki、Fukuma Tomoyuki、Kagawa Yoshihiko、Fujita Satoshi、Kogue Ryota、Umino Maki、Maeda Masayuki、Sakuma Hajime、Dohi Kaoru、Tomimoto Hidekazu
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 16 Pages: 818288-818288

    • DOI

      10.3389/fncel.2022.818288

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10314, KAKENHI-PROJECT-19H03572, KAKENHI-PROJECT-20K08104, KAKENHI-PROJECT-21K07433, KAKENHI-PROJECT-21K12194, KAKENHI-PROJECT-17K17811, KAKENHI-PROJECT-19K07865, KAKENHI-PROJECT-19K17031
  • [Journal Article] Brain magnetic resonance imaging and cognitive alterations after ablation in patients with atrial fibrillation2021

    • Author(s)
      Kato Natsuko、Muraga Kanako、Hirata Yoshinori、Shindo Akihiro、Matsuura Keita、Ii Yuichiro、Shiga Mariko、Tabei Ken-ichi、Satoh Masayuki、Fujita Satoshi、Fukuma Tomoyuki、Kagawa Yoshihiko、Fujii Eitaro、Umino Maki、Maeda Masayuki、Sakuma Hajime、Ito Masaaki、Tomimoto Hidekazu
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 18995-18995

    • DOI

      10.1038/s41598-021-98484-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10314, KAKENHI-PROJECT-19H03572, KAKENHI-PROJECT-20K08104, KAKENHI-PROJECT-21K12194, KAKENHI-PROJECT-17K17811
  • [Journal Article] Micro-MRI improves the accuracy of clinical diagnosis in cerebral small vessel disease2021

    • Author(s)
      Ishikawa H, Niwa A, Kato S, Ii Y,Shindo A, Matsuura K, Nishiguchi Y, Tamura A, Taniguchi A, Maeda M, Hashizume Y, Tomimoto H
    • Journal Title

      Brain Communications

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03572
  • [Journal Article] Cortical Microinfarcts Detected by 3-Tesla Magnetic Resonance Imaging2020

    • Author(s)
      Ishikawa Hidehiro、Ii Yuichiro、Shindo Akihiro、Tabei Ken-ichi、Umino Maki、Ito Ai Ogawa、Matsuura Keita、Taniguchi Akira、Matsuyama Hirofumi、Niwa Atsushi、Ogura Toru、Yoshimaru Kimiko、Satoh Masayuki、Maeda Masayuki、Tomimoto Hidekazu
    • Journal Title

      Stroke

      Volume: 51 Issue: 3 Pages: 1010-1013

    • DOI

      10.1161/strokeaha.119.028202

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17811, KAKENHI-PROJECT-18K15446, KAKENHI-PROJECT-19H03572, KAKENHI-PROJECT-16K10315, KAKENHI-PROJECT-20K08104
  • [Journal Article] Chronic cerebral hypoperfusion activates AIM2 and NLRP3 inflammasome2020

    • Author(s)
      Matsuyama Hirofumi、Shindo Akihiro、Shimada Takuya、Yata Kenichiro、Wakita Hideaki、Takahashi Ryosuke、Tomimoto Hidekazu
    • Journal Title

      Brain Research

      Volume: 1736 Pages: 146779-146779

    • DOI

      10.1016/j.brainres.2020.146779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03572, KAKENHI-PROJECT-18K16557
  • [Journal Article] Chronic cerebral hypoperfusion upregulates leptin receptor expression in astrocytes and tau phosphorylation in tau transgenic mice.2019

    • Author(s)
      Shimada T, Shindo A, Matsuyama H, Yata K, Niwa A, Sasaki R, Ayaki T, Maki T, Wakita H, Tomimoto H.
    • Journal Title

      Neuroscience Letters

      Volume: 704 Pages: 133-140

    • DOI

      10.1016/j.neulet.2019.04.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09684, KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-18K16557, KAKENHI-PROJECT-19K16277, KAKENHI-PROJECT-19H03572
  • [Journal Article] Diffusion tensor imaging and magnetic resonance spectroscopy in a patient with adult onset tuberous sclerosis complex2018

    • Author(s)
      Ishikawa Hidehiro、Niwa Atsushi、Asahi Masaru、Matsuura Keita、Masuzugawa Satoshi、Niida Yo、Maeda Masayuki、Kondo Mineo、Tomimoto Hidekazu
    • Journal Title

      J Clin Neurosci

      Volume: 48 Pages: 108-110

    • DOI

      10.1016/j.jocn.2017.10.072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08980, KAKENHI-PROJECT-16K15246
  • [Journal Article] Proteomic profiling of exosomal proteins for blood-based biomarkers in Parkinson's Disease.2018

    • Author(s)
      Kitamura Y, Kojima M, Kurosawa T, Sasaki R, Ichihara S, Hiraku Y, Tomimoto H, Murata M, Oikawa S.
    • Journal Title

      Neuroscience

      Volume: 392 Pages: 121-128

    • DOI

      10.1016/j.neuroscience.2018.09.017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19806, KAKENHI-PROJECT-18K19673, KAKENHI-PROJECT-16H05255, KAKENHI-PROJECT-16H05829, KAKENHI-PROJECT-18H03038, KAKENHI-PROJECT-15K15237, KAKENHI-PROJECT-26305023
  • [Journal Article] Comparison of Premortem Magnetic Resonance Imaging and Postmortem Autopsy Findings of a Cortical Microinfarct2018

    • Author(s)
      Ishikawa Hidehiro、Ii Yuichiro、Niwa Atsushi、Shindo Akihiro、Ito Ai、Matsuura Keita、Sasaki Ryogen、Uno Kenichiro、Maeda Masayuki、Tomimoto Hidekazu
    • Journal Title

      Journal of Stroke and Cerebrovascular Diseases

      Volume: 27 Issue: 10 Pages: 2623-2626

    • DOI

      10.1016/j.jstrokecerebrovasdis.2018.05.037

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15446, KAKENHI-PROJECT-16K15246
  • [Journal Article] Background and distribution of lobar microbleeds in cognitive dysfunction.2017

    • Author(s)
      Matsuyama H, Ii Y, Maeda M, Umino M, Ueda Y, Tabei KI, Kida H, Satoh M, Shindo A, Taniguchi A, Takahashi R, Tomimoto H1
    • Journal Title

      Brain Behav.

      Volume: 7 Issue: 11

    • DOI

      10.1002/brb3.856

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10314, KAKENHI-PROJECT-16K10315, KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-17K17811, KAKENHI-PROJECT-25870325
  • [Journal Article] Detection of cerebral amyloid angiopathy by 3-T magnetic resonance imaging and amyloid positron emission tomography in a patient with subcortical ischaemic vascular dementia2017

    • Author(s)
      Kida H, Satoh M, Ii Y, Fukuyama H, Maeda M, Tomimoto H.
    • Journal Title

      Psychogeriatrics

      Volume: 17 Issue: 1 Pages: 70-72

    • DOI

      10.1111/psyg.12187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Journal Article] Double-seropositive myasthenia gravis with acetylcholine receptor and low-density lipoprotein receptor-related protein 4 antibodies associated with invasive thymoma.2017

    • Author(s)
      3.Ishikawa H, Taniguchi A, Ii Y, Higuchi O, Matsuo H, Nakane S, Asahi M, Niwa A, Tomimoto H.
    • Journal Title

      Neuromuscul Disord.

      Volume: 27 Issue: 10 Pages: 914-914

    • DOI

      10.1016/j.nmd.2017.06.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-15K08636
  • [Journal Article] Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer's disease.2017

    • Author(s)
      Kitamura Y, Usami R, Ichihara S, Kida H, Satoh M, Tomimoto H, Murata M, Oikawa S.
    • Journal Title

      Neurol Res.

      Volume: 39 Issue: 3 Pages: 231-238

    • DOI

      10.1080/01616412.2017.1281195

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05255, KAKENHI-PROJECT-16H05829, KAKENHI-PROJECT-26293148, KAKENHI-PROJECT-15K15235, KAKENHI-PROJECT-15K15237
  • [Journal Article] Complement Activation in Capillary Cerebral Amyloid Angiopathy2017

    • Author(s)
      Matsuo Ko、Shindo Akihiro、Niwa Atsushi、Tabei Ken-ichi、Akatsu Hiroyasu、Hashizume Yoshio、Akiyama Haruhiko、Ayaki Takashi、Maki Takakuni、Sawamoto Nobukatsu、Takahashi Ryosuke、Oikawa Shinji、Tomimoto Hidekazu
    • Journal Title

      Dement Geriatr Cogn Disord

      Volume: 44 Issue: 5-6 Pages: 343-353

    • DOI

      10.1159/000486091

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-15K15237, KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-17K17811, KAKENHI-PROJECT-25870325, KAKENHI-PROJECT-16H06277
  • [Journal Article] Comparative Analysis of Cortical Microinfarcts and Microbleeds using 3.0-Tesla Postmortem Magnetic Resonance Images and Histopathology.2017

    • Author(s)
      Niwa A, Ii Y, Shindo A, Matsuo K, Ishikawa H, Taniguchi A, Takase S, Maeda M, Sakuma H, Akatsu H, Hashizume Y, Tomimoto H.
    • Journal Title

      J Alzheimers Dis.

      Volume: 59 Issue: 3 Pages: 951-959

    • DOI

      10.3233/jad-161242

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10315, KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-16H06277
  • [Journal Article] Detection of Low-Signal Pulvinar Areas Using Diffusion-Weighted Imaging in Patients with Dementia Experiencing Visual Hallucinations.2016

    • Author(s)
      Sugiura M, Satoh M, Tabei KI, Saito T, Mori M, Abe M, Kida H, Maeda M, Sakuma H, Tomimoto H.
    • Journal Title

      Dement Geriatr Cogn Dis Extra

      Volume: 6 Pages: 458-464

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Journal Article] Astrocyte-Derived Pentraxin 3 Supports Blood-Brain Barrier Integrity Under Acute Phase of Stroke2016

    • Author(s)
      Shindo A, Maki T, Mandeville ET, Liang AC, Egawa N, Itoh K, Itoh N, Borlongan M, Holder JC, Chuang TT, McNeish JD, Tomimoto H, Lok J, Lo EH, Arai K.
    • Journal Title

      Stroke

      Volume: 47 Issue: 4 Pages: 1094-100

    • DOI

      10.1161/strokeaha.115.012133

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-16K20005
  • [Journal Article] Neuropsychological features of microbleeds and cortical microinfarct detected by high resolution magnetic resonance imaging.2016

    • Author(s)
      Ueda Y, Satoh M, Tabei K, Kida H, Ii Y, Asahi M, Maeda M, Sakuma H, Tomimoto H
    • Journal Title

      J Alzheimers Dis.

      Volume: 53 Issue: 1 Pages: 315-25

    • DOI

      10.3233/jad-151008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-25870325
  • [Journal Article] Subcortical ischemic vascular disease: roles of oligodendrocyte function in experimental models of subcortical white-matter injury.2016

    • Author(s)
      Shindo A, Liang AC, Maki T, Miyamoto N, Tomimoto H, Lo EH, Arai K.
    • Journal Title

      J Cereb Blood Flow Metab.

      Volume: 36 Pages: 187-98

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Journal Article] A longitudinal study of neuromelanin-sensitive magnetic resonance imaging in Parkinson’s disease.2016

    • Author(s)
      Matsuura K, Maeda M, Tabei K, Umino M, Kajikawa H, Satoh M, Kida H, Tomimoto H.
    • Journal Title

      Neuroscience Letters

      Volume: 633 Pages: 112-17

    • DOI

      10.1016/j.neulet.2016.09.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-25870325
  • [Journal Article] A mouse model of chronic cerebral hypoperfusion characterizing features of cognitive impairment2014

    • Author(s)
      Ihara M, Taguchi A, Maki T, Washida K, Tomimoto H
    • Journal Title

      Methods Mol Biol

      Volume: 1135 Pages: 95-102

    • DOI

      10.1007/978-1-4939-0320-7_8

    • ISBN
      9781493903191, 9781493903207
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Clinical and neuropathological findings in a patient with familial Alzheimer disease showing a mutation in the PSEN1 gene2013

    • Author(s)
      Niwa A, MatsuoK, Shindo A, Yata K,Tomimoto H.
    • Journal Title

      Neuropathology

      Volume: 33 Pages: 199-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590929
  • [Journal Article] A novel protein S gene mutation combined with protein S Tokushima mutation in a patient with superior sagittal sinus thrombosis2012

    • Author(s)
      Shindo A, Tomimoto H
    • Journal Title

      J Neurol

      Volume: 259(1) Issue: 1 Pages: 178-179

    • DOI

      10.1007/s00415-011-6122-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005, KAKENHI-PROJECT-24590692
  • [Journal Article] Cerebral hypoperfusion induces microinfarcts in cerebral amyloid angiopathy2012

    • Author(s)
      Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, Kitamura A, Washida K, Yamada M, Ito H, Tomimoto H, Takahashi R, Ihara M
    • Journal Title

      Acta Neuropathol

      Volume: 123(3) Issue: 3 Pages: 381-394

    • DOI

      10.1007/s00401-011-0925-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Selective white matter abnormalities in a novel rat model of vascular dementia2012

    • Author(s)
      Kitamura A, Fujita Y, Oishi N, KalariaR N, Washida K, Maki T, Okamoto Y, HaseY, Yamada M, Takahashi J, Ito H, Tomimoto H, Fukuyama H, Takahashi R, Ihara M
    • Journal Title

      Neurobiology of Aging

      Volume: 33 Issue: 5 Pages: 25-35

    • DOI

      10.1016/j.neurobiolaging.2011.10.033

    • NAID

      120003988349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22220003, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article]2011

    • Author(s)
      Yata K, Oikawa S, Sasaki R, Shindo A, Yang R, Murata M, Kanamaru K, Tomimoto H.
    • Journal Title

      Brain Res

      Volume: 1410 Pages: 12-23

    • Data Source
      KAKENHI-PROJECT-21256005
  • [Journal Article] Astrocytic neuroprotection through induction of cytoprotective molecules ; a proteomic analysis of mutant P301S tau-transgenic mouse2011

    • Author(s)
      Yata K, Tomimoto H
    • Journal Title

      Brain Res

      Volume: 2(1410) Pages: 12-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Journal Article] Angiogenic roles of adreno medullin through VEGF induction2011

    • Author(s)
      Maki T, Ihara M, Fujita Y, Nambu T, Harada H, Ito H, Nakao K, Tomimoto H, Takahashi R
    • Journal Title

      Neuroreport

      Volume: 22 Issue: 9 Pages: 442-447

    • DOI

      10.1097/wnr.0b013e32834757e4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Attenuation of brain damage and cognitive impairment by direct renin inhibition in mice with chronic cerebral hypoperfusion.2011

    • Author(s)
      Dong YF, Kataoka K, Toyama K, Sueta D, Koibuchi N, Yamamoto E, Yata K, Tomimoto H, Ogawa H, Kim-Mitsuyama S
    • Journal Title

      Hypertension.

      Volume: 58 Pages: 635-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590929
  • [Journal Article] Watershed Infarcts in a multiple microembolic model of monkey2011

    • Author(s)
      Maki T, Wakita H, Mase M, Itagaki I, Saito N, Ono F, Adachi K, Ito H, Takahashi R, Ihara M, Tomimoto H
    • Journal Title

      Neuroscience Letters

      Volume: 499 Issue: 2 Pages: 80-83

    • DOI

      10.1016/j.neulet.2011.05.036

    • NAID

      120003238944

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-21591106, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011

    • Author(s)
      Tomimoto H
    • Journal Title

      Stroke

      Volume: 42(4) Issue: 4 Pages: 1122-8

    • DOI

      10.1161/strokeaha.110.603399

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005, KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice.2011

    • Author(s)
      Maki T, Ihara M, Fujita Y, Nambu T, Miyashita K, Yamada M, Washida K, Nishio K, Ito H, Harada H, Yokoi H, Arai H, Itch H, Nakao K, Takahashi R, Tomimoto H
    • Journal Title

      Stroke 42

      Pages: 1122-1128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Astrocytic neuroprotection through induction of cytoprotective molecules; a proteomic analysis of mutant P301S tau-transgenic mouse2011

    • Author(s)
      Yata K, Oikawa S, Sasaki R, Shindo A, Yang R, Murata M, Kanamaru K, Tomimoto H
    • Journal Title

      Brain Res

      Volume: 1410 Pages: 12-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390162
  • [Journal Article] The influence of chronic cerebral hypoperfusion on cognitive function and amyloid b metabolism in APP overexpressing mice2011

    • Author(s)
      Yamada M, Ihara M, Okamoto Y, Maki T, Washida K, Kitamura A, Hase Y, Ito H, Takao K, Miyakawa T, Kalaria RN, Tomimoto H, Takahashi R
    • Journal Title

      PLoS One

      Volume: 6 Issue: 1 Pages: e16567-e16567

    • DOI

      10.1371/journal.pone.0016567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233
  • [Journal Article] Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes2011

    • Author(s)
      Ihara M, Tomimoto H
    • Journal Title

      J Aging Res

      Volume: 2011 Pages: 978761-978761

    • DOI

      10.4061/2011/978761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Higher-dose glutathione therapy for Parkinson' s disease in Japan: is it really safe?2010

    • Author(s)
      Naito Y, Matsuo K, Kokubo Y, Narita Y, Tomimoto H
    • Journal Title

      Mov Disord.

      Volume: 25(7)

    • Data Source
      KAKENHI-PROJECT-21256005
  • [Journal Article] 発作の誘因としてValsarva負荷の関与が疑われた一過性全健忘の3症例;高磁場脳MRIを用いた検討2010

    • Author(s)
      坂井利行、冨本秀和
    • Journal Title

      臨床神経学

      Volume: 50(7) Pages: 473-477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Journal Article] Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to peroxisome proliferator-activated receptor-γ activation in mice with chronic cerebral hypoperfusion.2010

    • Author(s)
      Washida K, Ihara M, Nishio K, Fujita Y, Maki T, Yamada M, Takahashi J, Wu X, Kihara T, Ito H, Tomimoto H, Takahashi R.
    • Journal Title

      Stroke 41

      Pages: 1798-1806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to peroxisome proliferator-activated receptor-γ activation in mice with chronic cerebral hypoperfusion.2010

    • Author(s)
      Washida K, Ihara M, Nishio K, Fujita Y, Maki T, Yamada M, Takahashi J, Wu X, Kihara T, Ito H, Tomimoto H, Takahashi R.
    • Journal Title

      Stroke

      Volume: 41 Pages: 1798-1806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Higher-dose glutathione therapy for Parkinson's disease in Japan : is it really safe?2010

    • Author(s)
      Naito Y, Kokubo Y, Tomimoto H.
    • Journal Title

      Mov Disord.

      Volume: May15;25(7) Pages: 962-963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Journal Article] A mouse model characterizing features of vascular dementia with hippocampal atrophy.2010

    • Author(s)
      Nishio K, Ihara M, Yamasaki N, Kalaria RN, Maki T, Fujita Y, Ito H, Oishi N, Fukuyama H, Miyakawa T, Takahashi R, Tomimoto H.
    • Journal Title

      Stroke

      Volume: 41 Pages: 1278-1284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] A mouse model characterizing features of vascular dementia with hippocampal atrophy.2010

    • Author(s)
      Nishio K, Thara M, Yamasaki N, Kalaria RN, Makia T, Fujita Y, Ito H, Oishi N, Fukuyama H, Miyakawa T, Takahashi R, Tomimoto H
    • Journal Title

      Stroke 41(6)

      Pages: 1278-1284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] 痙性対麻痺におけるbacrofen持続髄注療法2010

    • Author(s)
      内藤寛、冨本秀和
    • Journal Title

      神経治療学

      Volume: 27(5) Pages: 689-695

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Journal Article] HTRA1変異と家族性虚血性脳小血管病の関連2010

    • Author(s)
      丹羽篤、冨本秀和
    • Journal Title

      分子脳血管病

      Volume: 9 Pages: 104-106

    • Data Source
      KAKENHI-PROJECT-21256005
  • [Journal Article] Cortical microinfarcts in Alzheimer's disease and subcortical vascular dementia2009

    • Author(s)
      Okamoto Y, Ihara M, Fujita Y, Ito H, Takahashi R, Tomimoto H.
    • Journal Title

      Neuroreport 20

      Pages: 990-996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Chronic cerebral hypoperfusion accelerates amyloid deposition in APPSwInd transgenic mice2009

    • Author(s)
      Kitaguchi H, Tomimoto H, Ihara M, Shibata M, Uemura K, Kalaria RN, Kihara T, Asada-Utsugi M, Kinoshita A, Takahashi R.
    • Journal Title

      Brain Research 1294

      Pages: 202-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Chronic cerebral hypoperfusion accelerates amyloid deposition in APPSwInd transgenic mice.2009

    • Author(s)
      Kitaguchi H, Tomimoto H, Ihara M, Shibata M, Uemura K, Kalaria RN, Kihara T, Asada-UtsugiM, Kinoshita A, Takahashi R.
    • Journal Title

      Brain Research 1294

      Pages: 202-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Edaravone, a free radical scavenger, mitigates both gray and white matter damages after global cerebral ischemia in rats2009

    • Author(s)
      Kubo K, Nakao S, Jomura S, Sakamoto S, Miyamoto E, Xu Y, Tomimoto H, Inada T, Shingu K.
    • Journal Title

      Brain Research 1279

      Pages: 139-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] 脳血管性認知症の分子病態2008

    • Author(s)
      鷲田和夫、猪原匡史、冨本秀和
    • Journal Title

      Medical Science Digest 34

      Pages: 391-394

    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Cilostazol alleviates cerebral small-vessel pathology and white-matt er lesions in stroke-prone spontaneously hypertensive rats.2008

    • Author(s)
      Fujita Y, Lin JX, Takahashi R, Tomimoto H
    • Journal Title

      Brain Res. 1203

      Pages: 170-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Journal Article] Expression of S 100 protein and protective effect of arundic acid on the rat brain in chronic cerebral hypoperfusion2007

    • Author(s)
      Ohtani R, Tomimoto H, Wakita H, Kitaguchi H, Nakaji K, Takahashi R
    • Journal Title

      Brain Research 1135

      Pages: 195-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Subinsular vascular lesions; an analysis of 119 consecutive autopsied brains.2007

    • Author(s)
      Tomimoto H, Lin Jin-Xi, Ihara M, Ohtani R, Matsuo A, Miki Y
    • Journal Title

      European Journal of Neurology 14(1)

      Pages: 95-101

    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Capillary beds are decreased in Alzheimer's disease, but not in Binswanger's disease.2007

    • Author(s)
      Kitaguchi H,Ihara M,Saiki H,Takahashi R and Tomimoto H
    • Journal Title

      Neurosci Lett 417

      Pages: 128-131

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Expression of S100 protein and protective effect of arundic acid on the rat brain in chronic cerebral hypoperfusion2007

    • Author(s)
      Ohtani R,Tomimoto H,Wakita H,Kitaguchi H,Nakaji K,Takahashi R
    • Journal Title

      Brain Research 1135

      Pages: 195-200

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Selective impairment of working memory in a mouse model of chronic cerebral hypoperfusion2007

    • Author(s)
      Shibata M, Yamasaki N, Miyakawa T, Ohta ni R, Ihaza M, Takahashi R, Tomimoto H
    • Journal Title

      Stroke 38

      Pages: 2826-2832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Capillary beds are decreased in Alzheimer's disease, but not in Binswanger's disease.2007

    • Author(s)
      Kitaguchi H, Ihara M, Saiki H, Takahashi R, Tomimoto H.
    • Journal Title

      Neurosci Lett 417

      Pages: 128-131

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Capillary beds are decreased in Alzheimer's disease, but not in Binswanger's disease.2007

    • Author(s)
      Kitaguchi H, Ihara M, Saiki H, Takahashi R, Tomimoto H.
    • Journal Title

      Neuroscience Letters 417(2)

      Pages: 128-131

    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Expression of S100 protein and protective effect of arundic acid on the rat brain in chronic cerebral hypoperfusion.2007

    • Author(s)
      Ohtani R, Tomimoto H, Wakita H, Kitaguchi H, Nakaji K, Takahashi R.
    • Journal Title

      Brain Research 1135

      Pages: 195-200

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Selective impairment of working memory in a mouse model of chronic cerebral hypoperfusion.2007

    • Author(s)
      Shibata M, Yamasaki N, Miyakawa T, Ohta ni R, Ihara M, Takahashi R, Tomimoto H
    • Journal Title

      Stroke 38

      Pages: 195-200

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity2007

    • Author(s)
      Ihara M, Yamasaki N, Hagiwara A, Tanigaki A, Kitano A, Hikawa R, Tomimoto H, Noda M, Takanashi M, Mori H, Hattori N, Miyakawa T, Kinoshita M.
    • Journal Title

      Neuron 53(4)

      Pages: 519-533

    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Expression of S100 protein and protective effect of arundic acid on the rat brain in chronic cerebral hypoperfusion2007

    • Author(s)
      Ohtani R, Tomimoto H, Wakita H, Kitaguchi H, Nakaji K, Takahashi R
    • Journal Title

      Brain Research 1135(1)

      Pages: 195-200

    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Capillary beds are decreased in Alzheimer's disease, but not in Binswanger's disease2007

    • Author(s)
      Kitaguchi H, Ihara M, Saiki H, Takahashi R, Tomimoto H
    • Journal Title

      Neurosci Lett 417

      Pages: 128-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Selective impairment of working memory in a mouse model of chronic cerebral hypoperfusion.2007

    • Author(s)
      Shibata M,Yamasaki N,Miyakawa T,Ohta ni R,Ihara M,Takahashi R,Tomimoto H
    • Journal Title

      Stroke 38

      Pages: 2826-2832

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] MMP-2 play a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents.2006

    • Author(s)
      Nakaji K,Ihara M,Takahashi C,Itohara S,Noda N,Takahashi R and Tomimoto H
    • Journal Title

      Stroke 37

      Pages: 2816-2823

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] MMP-2 play a critical rolde in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents.2006

    • Author(s)
      Nakaji K, Ihara M, Takahashi C, Itohara S, Noda N, Takahashi R, Tomimoto H.
    • Journal Title

      Stroke 37

      Pages: 2816-2823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Loss of cholinergic pathways in vascular dementia of the Binswanger type.2005

    • Author(s)
      Tomimoto H et al.
    • Journal Title

      Dementia Geriatric Cognitive Disorders 19・5-6

      Pages: 282-288

    • Data Source
      KAKENHI-PROJECT-17590873
  • [Journal Article] Astroglial expression of ceramide in Alzheimer's disease brains : A role during neuronal apoptosis2005

    • Author(s)
      Satoi H, Tomimoto H et al.
    • Journal Title

      Neuroscience 130, 3

      Pages: 657-666

    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Blood-brain barrier is impaired in the hippocampus of young adult spontaneously hypertensive rat (SHR).2004

    • Author(s)
      Ueno M, Sakamoto H, Tomimoto H et al.
    • Journal Title

      Acta Neuropathol (Berl) 107, 6

      Pages: 528-532

    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Paroxysmal dysarthria and ataxia after midbrain infarction.2004

    • Author(s)
      Matsui M, Tomimoto H et al.
    • Journal Title

      Neurology 63, 2

      Pages: 345-347

    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Upregulation of ceramide and its regulating mechanism in a rat Model of chronic cerebral ischemia.2004

    • Author(s)
      Ohtani R, Tomimoto H et al.
    • Journal Title

      Brain Research 1023

      Pages: 31-40

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Upregulation of ceramide and its regulating mechanism in a rat model of chronic cerebral ischemia.2004

    • Author(s)
      Ohtani R, Tomimoto H et al.
    • Journal Title

      Brain Research 1023, 1

      Pages: 31-40

    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Blood-brain barrier is impaired in the hippocampus of young adult spontaneously hypertensive rat (SHR).2004

    • Author(s)
      Ueno M, Sakamoto H, Tomimoto H et al.
    • Journal Title

      Acta Neuropathologica (Berl) 107

      Pages: 532-538

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Blood-brain barrier is impaired in the hippocampus of young Adult spontaneously hypertensive rat(SHR).2004

    • Author(s)
      Ueno M, Sakamoto H, Tomimoto H et al.
    • Journal Title

      Acta Neuropathol (Berl) 107

      Pages: 532-538

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Decrease in cortical benzodiazepine receptors in symptomatic patients with leukoaraiosis : a positron emission tomography study.2004

    • Author(s)
      Ihara M, Tomimoto H et al.
    • Journal Title

      Stroke 35

      Pages: 942-947

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Pure pandysautonomia as a complication of chronic lymphocytic leukemia.2004

    • Author(s)
      Yamashita Y, Tomimoto H et al.
    • Journal Title

      Neurology 62, 10

      Pages: 1903-1904

    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Different mechanisms of corpus callosum atrophy in Alzheimer's disease and vascular dementia.2004

    • Author(s)
      Tomimoto H, Lin J-Xi et al.
    • Journal Title

      Jouenal of Neurology 251

      Pages: 398-406

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Upregulation of ceramide and its regulating mechanism in a rat model of chronic cerebral ischemia.2004

    • Author(s)
      Ohtani R, Tomimoto H et al.
    • Journal Title

      Brain Research 1023

      Pages: 31-40

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Topographical and cytopathological lesion analysis of the white matter in Binswanger's disease brains.2004

    • Author(s)
      Akiguchi I, Tomimoto H et al.
    • Journal Title

      Acta Neuropathol (Berl) 107, 6

      Pages: 563-570

    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies.2003

    • Author(s)
      Ihara M, Tomimoto H et al.
    • Journal Title

      Journal of Biological Chemistry 278

      Pages: 24095-24102

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat.2003

    • Author(s)
      Tomimoto H, Ihara M et al.
    • Journal Title

      Acta Neuropathologica (Berlin) 106

      Pages: 527-534

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Association of the cytoskeletal GTP-binding protein Sept4/H5 Wit cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies.2003

    • Author(s)
      Ihara M, Tomimoto H et al.
    • Journal Title

      Journal of Biological Chemistry 278

      Pages: 24095-24102

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat.2003

    • Author(s)
      Tomimoto H, Ihara M et al.
    • Journal Title

      Acta Neuropathologica (Berl). 106

      Pages: 527-534

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Different mechanisms of corpus callosum atrophy in Alzheimer's disease and vascular dementia.2003

    • Author(s)
      Tomimoto H, Lin J-Xi et al.
    • Journal Title

      Journal of Neurology 251

      Pages: 398-406

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570592
  • [Journal Article] Selective impairment of working memory in a mouse model of chronic cerebral hypoperfusion

    • Author(s)
      Shibata M, Yamasaki N, Miyakawa T, Ohtani R, Ihara M, Takahashi R, Tomimoto H
    • Journal Title

      Stroke 印刷中

    • Data Source
      KAKENHI-PROJECT-18590936
  • [Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice.

    • Author(s)
      Maki T, Ihara M, Fujita Y, Nambu T, Miyashita K, Yamada M, Washida K, Nishio K, Ito H, Harada H, Yokoi H, Arai H, Itoh H, Nakao K, Takahashi R, Tomimoto H.
    • Journal Title

      Stroke

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Patent] 脳アミロイド血管症の末梢血バイオマーカー2017

    • Inventor(s)
      冨本 秀和、他
    • Industrial Property Rights Holder
      国立大学法人三重大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] 脳アミロイド血管症2021

    • Author(s)
      冨本秀和
    • Organizer
      第46回日本脳卒中学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03572
  • [Presentation] Serum protein biomarkers in the diagnosis of cerebral amyloid angiopathy (CAA).2021

    • Author(s)
      Nishiguchi Y, Tachibana K, Mori Y, Matsuyama H, Shindo A, Oikawa S,Tomimoto H.
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19H03572
  • [Presentation] 脳小血管病の病態、治療、研究2021

    • Author(s)
      冨本秀和
    • Organizer
      第62回 日本神経病理学会総会学術研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03572
  • [Presentation] 脳アミロイド血管症と頭蓋内出血リスク2020

    • Author(s)
      冨本秀和
    • Organizer
      第45回日本脳卒中学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03572
  • [Presentation] アルツハイマー病患者血漿エクソソーム中のタンパク質解析2019

    • Author(s)
      森咲子、森有利絵、山路隆斗、舩山華奈子、小嶋みどり、佐藤正之、市原佐保子、埜村智之、石川雅一、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部第7回学術集会
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] Differentiation of cortical microinfarctions due to cerebral amyloid angiopathy from those caused by microembolism on 3T MRI2019

    • Author(s)
      Hidehiro Ishikawa, Yuichiro Ii, Akihiro Shindo, Masayuki Maeda, Ai Ito, Maki Umino, Keita Matsuura, Akira Taniguchi, Hidekazu Tomimoto
    • Organizer
      International Stroke Conference 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 微小塞栓と脳アミロイド血管症による皮質微小梗塞:3T-MRIによる検出と鑑別の試み2019

    • Author(s)
      石川 英洋、 伊井 裕一郎、新堂 晃大、 伊藤 愛、松山 裕文、松浦 慶太、 田部井 賢一、海野 真記、前田 正幸、 冨本 秀和
    • Organizer
      第44回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 認知症早期発見のためのバイオマーカー開発の近況2019

    • Author(s)
      冨本秀和
    • Organizer
      第37回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03572
  • [Presentation] 生活習慣と認知症リスクについて2018

    • Author(s)
      冨本秀和
    • Organizer
      第52回日本成人病(生活習慣病)学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 早期アルツハイマー病患者における血液バイオマーカーの探索2018

    • Author(s)
      舩山華奈子、森有利絵、小嶋みどり、北村祐貴、佐藤正之、市原佐保子、埜村智之、石川雅一、村田真理子、冨本秀和、及川伸二.
    • Organizer
      日本酸化ストレス学会東海支部第6回学術集会
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] Role of small vessel disease in the boundaries of large vessel disease and Alzheimer disease2018

    • Author(s)
      Hidekazu Tomimoto
    • Organizer
      19th International Congress of Neuropathology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] Comparative analysis of cortical microinfarcts on 3T MRI in patients with cerebral amyloid angiopathy and embolic stroke2018

    • Author(s)
      Hidehiro Ishikawa, Yuichiro Ii, Akihiro Shindo, Ai Ito, Ken-ichi Tabei, Hirofumi Matsuyama, Keita Matsuura, Maki Umino, Masayuki Maeda, Hidekazu Tomimoto
    • Organizer
      16th Asian Oceanian Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 微小脳血管病と片頭痛2018

    • Author(s)
      冨本秀和
    • Organizer
      第43回日本脳卒中学会学術集会(STROKE2018)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] Nosologic considerations on vascular dementia using SPECT and MRI2018

    • Author(s)
      Hidekazu Tomimoto
    • Organizer
      13th annual meeting of Taiwan Stroke Society(TSS)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 脳小血管病と脳卒中の未来地図2018

    • Author(s)
      冨本秀和
    • Organizer
      第43回日本脳卒中学会学術集会(STROKE2018)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 脳アミロイド血管症の診療最前線2017

    • Author(s)
      冨本秀和
    • Organizer
      第8回日本脳血管・認知症学会総会(VAS-COG Japan 2017)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 酸化損傷タンパク質を指標としたアルツハイマー病のバイオマーカーの探索2017

    • Author(s)
      辻本佳世、北村祐貴、木田博隆、佐藤正之、市原佐保子、埜村 智之、 石川雅一、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部第 5 回学術集会
    • Place of Presentation
      名古屋、愛知学院大学名城公園キャンパス
    • Year and Date
      2017-02-18
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] 血管性認知症 ;revisited2017

    • Author(s)
      冨本秀和
    • Organizer
      第36回日本認知症学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] アルツハイマー病患者の血漿中カルボニル化タンパク質のプロテオミクス解析2017

    • Author(s)
      辻本佳世、北村裕貴、森有利絵、木田博隆、佐藤正之、市原佐保子、埜村智之、石川雅一、村田真理子、冨本秀和、及川伸二.
    • Organizer
      日本プロテオーム学会2017大会
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] 【認知症医療の最前線】認知症の画像と病理;診断精度の向上のために2017

    • Author(s)
      冨本秀和
    • Organizer
      第59回日本老年医学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] アルツハイマー病患者血漿エクソソーム内タンパク質の発現量解析2017

    • Author(s)
      小嶋みどり、北村裕貴、森有利絵、木田博隆、佐藤正之、市原佐保子、埜村智之、石川雅一、村田真理子、冨本秀和、及川伸二.
    • Organizer
      日本プロテオーム学会2017大会
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] 脳小血管病の病理と臨床症状2017

    • Author(s)
      冨本秀和
    • Organizer
      第26回日本脳ドック学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 脳小血管病の病態と診断~日本と欧米の違いも含めて2017

    • Author(s)
      冨本秀和
    • Organizer
      第42回日本脳卒中学会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2017-03-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 認知症抑制は可能か?2016

    • Author(s)
      冨本秀和
    • Organizer
      第5回臨床高血圧フォーラム
    • Place of Presentation
      ステーションコンファレンス東京(東京都・千代田区)
    • Year and Date
      2016-05-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] 大脳白質病変は何を反映しているのか;MRI撮像法、評価法の比較による病態の理解2016

    • Author(s)
      冨本秀和
    • Organizer
      第58回日本老年医学会学術集会
    • Place of Presentation
      石川県立音楽堂、ANAクラウンプラザホテル金沢(石川県・金沢市)
    • Year and Date
      2016-06-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] パーキンソン病患者血漿中の酸化損傷タンパク質の解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部第4回学術大会
    • Place of Presentation
      鈴鹿市、鈴鹿医療科学大学
    • Year and Date
      2016-02-06
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] パーキンソン病の血漿中エクソソームのプロテオミクス解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      第86回日本衛生学会学術総会
    • Place of Presentation
      旭川市、旭川市民文化会館
    • Year and Date
      2016-05-11
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] 血管性認知症診療の新展開2016

    • Author(s)
      冨本秀和
    • Organizer
      第35回日本認知症学会学術集会
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2016-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] パーキンソン病患者血漿中のカルボニル化タンパク質の解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台市、仙台国際センター
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] パーキンソン病患者血漿中のカルボニル化タンパク質の解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台市、仙台国際センター
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] パーキンソン病の血漿中エクソソームのプロテオミクス解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      第86回日本衛生学会学術総会
    • Place of Presentation
      旭川市、旭川市民文化会館
    • Year and Date
      2016-05-11
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] 筋萎縮性側索硬化症の脳脊髄液における酸化損傷タンパク質の同定2016

    • Author(s)
      北村祐貴、菰田淳、二本松綾乃、佐々木良元、村田真理子、冨本秀和、及川伸二
    • Organizer
      第80回日本生化学会中部支部例会・シンポジウム
    • Place of Presentation
      津市、三重大学講堂
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] 筋萎縮性側索硬化症の脳脊髄液における酸化損傷タンパク質の同定2016

    • Author(s)
      北村祐貴、菰田淳、二本松綾乃、佐々木良元、村田真理子、冨本秀和、及川伸二
    • Organizer
      第80回日本生化学会中部支部例会
    • Place of Presentation
      津市、三重大学講堂
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] 脳小血管病の病態と診断2016

    • Author(s)
      冨本秀和
    • Organizer
      第41回日本脳卒中学会総会
    • Place of Presentation
      ロイトン札幌・札幌市教育文化会館(北海道・札幌市)
    • Year and Date
      2016-04-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15246
  • [Presentation] パーキンソン病患者血漿中の酸化損傷タンパク質の解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部第4回学術大会
    • Place of Presentation
      鈴鹿市、鈴鹿医療科学大学
    • Year and Date
      2016-02-06
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] 筋萎縮性側索硬化症の脳脊髄液におけるカルボニル化タンパク質の解析2015

    • Author(s)
      北村祐貴、菰田淳、二本松綾乃、佐々木良元、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本プロテオーム学会2015年会
    • Place of Presentation
      熊本市、熊本森都心プラザ
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-15K15237
  • [Presentation] 筋萎縮性側索硬化症の脳脊髄液におけるカルボニル化タンパク質の解析2015

    • Author(s)
      北村祐貴、菰田淳、二本松綾乃、佐々木良元、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本プロテオーム学会2015年会
    • Place of Presentation
      熊本市、熊本森都心プラザ
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] パーキンソン病患者の血漿におけるプロテオミクス解析2015

    • Author(s)
      北村 祐貴、都築 政弘、佐々木 良元、市原 佐保子、松永 誠治郎、水野 章、 村田 真理子、冨本 秀和、及川 伸二
    • Organizer
      日本酸化ストレス学会東海支部第3回学術大会
    • Place of Presentation
      名城大学、名古屋市
    • Year and Date
      2015-02-07
    • Data Source
      KAKENHI-PROJECT-24659300
  • [Presentation] パーキンソン病患者の血漿におけるプロテオミクス解析2015

    • Author(s)
      北村 祐貴、都築 政弘、佐々木 良元、市原 佐保子、松永 誠治郎、水野 章、 村田 真理子、冨本 秀和、及川 伸二
    • Organizer
      日本酸化ストレス学会東海支部第3回学術大会
    • Place of Presentation
      名城大学、名古屋市
    • Year and Date
      2015-02-07
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] パーキンソン病患者の血漿中カルボニル化タンパク質の同定2014

    • Author(s)
      北村祐貴, 都築政弘, 佐々木良元, 市原佐保子, 松永誠治郎, 水野章, 村田真理子, 冨本秀和, 及川伸二
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山市、岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-23390162
  • [Presentation] パーキンソン病患者の血漿中カルボニル化タンパク質の同定2014

    • Author(s)
      北村祐貴, 都築政弘, 佐々木良元, 市原佐保子, 松永誠治郎, 水野章, 村田真理子, 冨本秀和, 及川伸二
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Data Source
      KAKENHI-PROJECT-23390162
  • [Presentation] パーキンソン病患者の血漿中カルボニル化タンパク質の同定2014

    • Author(s)
      北村祐貴, 都築政弘, 佐々木良元, 市原佐保子, 松永誠治郎, 水野章, 村田真理子, 冨本秀和, 及川伸二
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山市、岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24659300
  • [Presentation] 皮質下血管性認知症;認知症疾患における位置づけ2011

    • Author(s)
      冨本秀和
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Presentation] In vivo detection of cortical microinfarction with ultrahigh-field MRI in subjects with cognitive impairment2011

    • Author(s)
      Li Y, Tomimoto H
    • Organizer
      VasCog 2011
    • Place of Presentation
      Lille France
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Presentation] 大脳白質病変と認知症・認知障害2011

    • Author(s)
      冨本秀和
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Presentation] Significance of cortical SAH as a putative marker tor cerebral amyloid angiopathy in patients with cognitive impairment2011

    • Author(s)
      Tomimoto H.
    • Organizer
      VasCog 2011
    • Place of Presentation
      Lille France
    • Data Source
      KAKENHI-PROJECT-21256005
  • [Presentation] マウス慢性脳低灌流モデルの認知機能障害および白質障害に対するテルミサルタンの効果2010

    • Author(s)
      鷲田和夫, 猪原匡史, 西尾佳子, 藤田裕之, 眞木崇州, 山田真人, 高橋淳, 呉暁峰, 木原武士, 伊東秀文, 冨本秀和, 高橋良輔
    • Organizer
      日本循環代謝学会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] A comparative study on the distribution of cortical microinfarcts between the brains with Alzheimer's disease and subcortical vascular dementia2009

    • Author(s)
      Y Okamoto, M Ihara, Y Fujita, R Takahashi, H Tomimoto
    • Organizer
      The 4th Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG)
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] Protective effect of cilostazol against the no-reflow phenomenon in transient cerebral ischemia2009

    • Author(s)
      Y Hase, Y Fujita, M Ihara, H Tomimoto
    • Organizer
      The 4th Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG)
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] A role of intercellular adhesion molecules in the pathogenesis of white matter lesion ; an analysis of human brains2009

    • Author(s)
      M Yamada, M Ihara, H Tomimoto
    • Organizer
      The 4th Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG)
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] マウス慢性脳低灌流モデルに対する血管前駆細胞移植の効果2009

    • Author(s)
      鷲田和夫, 猪原匡史, 高橋淳, 山下潤, 伊東秀文, 冨本秀和, 高橋良輔
    • Organizer
      日本神経学会総会
    • Place of Presentation
      仙台市
    • Year and Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] Long standing chronic cerebral hypoperfusion accelerates Aβ aggregation, brain atrophy and memory impairment PCS-22009

    • Author(s)
      H Tomimoto
    • Organizer
      The 4th Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG)
    • Place of Presentation
      Singapore
    • Year and Date
      2009-01-13
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] マウス慢性脳低灌流モデルに対する血管前駆細胞移植の効果2009

    • Author(s)
      鷲田和夫, 猪原匡史, 高橋淳, 山下潤, 伊東秀文, 冨本秀和, 高橋良輔
    • Organizer
      日本神経学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] トランスジェニックマウスを用いたHIF-1活性イメージング2008

    • Author(s)
      藤田祐之, 冨本秀和, 高橋良輔, 近藤科江
    • Organizer
      日本神経学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-19790604
  • [Presentation] Binswanger病の脳機能画像2008

    • Author(s)
      冨本秀和
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-20590996
  • [Presentation] アルツハイマー病におけるcapillary networkの障害;Silver impregnation techniqueによる剖検脳の検討。2006

    • Author(s)
      北口浩史、猪原匡史、高橋良輔、冨本秀和
    • Organizer
      第47回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2006-05-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Presentation] Capillary network is impaired in Alzheimer's disease ; an analysis of autopsied brains using silver impregnation method.2006

    • Author(s)
      Kitaguchi H, Ihara M, Takahashi R, Tomimoto H.
    • Organizer
      47th annual meeting of Japanse Neurological Association
    • Year and Date
      2006-05-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590936
  • [Presentation] パーキンソン病における血漿タンパク質の酸化損傷度解析

    • Author(s)
      都築政弘、佐々木良元、市原佐保子、松永誠治郎、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部 第2回学術大会
    • Place of Presentation
      岐阜市、岐阜薬科大学本部学舎
    • Data Source
      KAKENHI-PROJECT-23390162
  • [Presentation] アルツハイマー病患者の血漿中のバイオマーカーの探索

    • Author(s)
      北村 祐貴、宇佐美 良子、紙本 貴之、木田 博隆、佐藤 正之、冨本 秀和、 及川 伸二
    • Organizer
      第23回海馬と高次脳機能学会
    • Place of Presentation
      湯涌創作の森、金沢市
    • Year and Date
      2014-10-11 – 2014-10-12
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] パーキンソン病における血漿タンパク質の酸化損傷度解析

    • Author(s)
      都築政弘、佐々木良元、市原佐保子、松永誠治郎、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部 第2回学術大会
    • Place of Presentation
      岐阜市、岐阜薬科大学本部学舎
    • Data Source
      KAKENHI-PROJECT-24659300
  • [Presentation] アルツハイマー病患者の血漿中におけるプロテオミクス解析

    • Author(s)
      北村 祐貴、宇佐美 良子、木田 博隆、佐藤 正之、市原 佐保子、松永 誠治郎、 水野 章、冨本 秀和、村田 真理子、及川 伸二
    • Organizer
      第85回日本衛生学会総会
    • Place of Presentation
      和歌山県民文化会館・ホテルアバローム紀の国、和歌山市
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] アルツハイマー病患者の血漿中におけるプロテオミクス解析

    • Author(s)
      北村 祐貴、宇佐美 良子、木田 博隆、佐藤 正之、市原 佐保子、松永 誠治郎、 水野 章、冨本 秀和、村田 真理子、及川 伸二
    • Organizer
      第85回日本衛生学会総会
    • Place of Presentation
      和歌山県民文化会館・ホテルアバローム紀の国、和歌山市
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-24659300
  • [Presentation] パーキンソン病患者の血漿中カルボニル化タンパク質の同定

    • Author(s)
      北村祐貴, 都築政弘, 佐々木良元, 市原佐保子, 松永 誠治郎, 水野章, 村田真理子, 冨本 秀和, 及川 伸二
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター、岡山市
    • Year and Date
      2014-05-25 – 2014-05-27
    • Data Source
      KAKENHI-PROJECT-26293148
  • [Presentation] アルツハイマー病患者の血漿中のバイオマーカーの探索

    • Author(s)
      北村 祐貴、宇佐美 良子、紙本 貴之、木田 博隆、佐藤 正之、冨本 秀和、 及川 伸二
    • Organizer
      第23回海馬と高次脳機能学会
    • Place of Presentation
      湯涌創作の森、金沢市
    • Year and Date
      2014-10-11 – 2014-10-12
    • Data Source
      KAKENHI-PROJECT-24659300
  • [Presentation] パーキンソン病患者の血漿中カルボニル化タンパク質の同定

    • Author(s)
      北村祐貴, 都築政弘, 佐々木良元, 市原佐保子, 松永 誠治郎, 水野章, 村田真理子, 冨本 秀和, 及川 伸二
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山コンベンションセンター、岡山市
    • Year and Date
      2014-05-25 – 2014-05-27
    • Data Source
      KAKENHI-PROJECT-24659300
  • 1.  OIKAWA Shinji (10277006)
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    # of Collaborated Products: 31 results
  • 2.  MURATA Mariko (10171141)
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 2 results
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    # of Collaborated Products: 8 results
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    # of Collaborated Projects: 1 results
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  • 20.  MATSUI Masaru (60378750)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SAIKI Hidemoto (90378688)
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    # of Collaborated Products: 4 results
  • 22.  ONO Masahiro (80336180)
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
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  • 27.  周 びん (00598774)
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    # of Collaborated Products: 8 results
  • 34.  Hashizume Yoshio
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  • 35.  Niwa Atsushi
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  • 36.  Ishikawa Hidehiro
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    # of Collaborated Products: 5 results
  • 37.  SAITO Satoshi
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  • 38.  YAMAMOTO Yumi
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  • 39.  AKATSU Hiroyasu
    # of Collaborated Projects: 0 results
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  • 40.  WAKITA Hideaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  村田 真理子子
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    # of Collaborated Products: 14 results
  • 42.  前田 正幸
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    # of Collaborated Products: 4 results
  • 43.  海野 真記
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    # of Collaborated Products: 3 results
  • 44.  田部井 賢一
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    # of Collaborated Products: 1 results
  • 45.  高橋 良輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 46.  伊東 秀文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 47.  新井田 要
    # of Collaborated Projects: 0 results
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  • 48.  平工 雄介
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    # of Collaborated Products: 1 results

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