KUBOTA Hiroshi 久保田広志

Researcher Number	80332724
Other IDs
Affiliation (based on the past Project Information) *help	2017: 秋田大学, 工学資源学部, 教授 2015: 秋田大学, 工学資源学研究科, 教授 2011 – 2014: 秋田大学, 工学(系)研究科(研究院), 教授 2010 – 2011: Akita University, 工学資源学研究科, 教授 2008 – 2009: Akita University, 工学資源学部, 准教授 … More 2007: Kyoto University, Inst. Frontier Med. Sci, Assistant Prof 2007: Kyoto University, 再生医科学研究所, 助教 2001 – 2006: 京都大学, 再生医科学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Cell biology / Biological Sciences Except Principal Investigator Plastic surgery / Cell biology
Keywords	Principal Investigator CCT / 分子シャペロン / フォールディング / タンパク質凝集 / 神経変性疾患 / RNAi / 基質特異性 / タンパク質分解 / ポリグルタミン病 / molecular chaperone … More / HSP60 / タンパク質相互作用 / 神経変成疾患 / 神経細胞死 / 蛍光イメージング / オリゴマー / 筋萎縮性側索硬化症 / substrate specificity / beta sheet / neurodegenerative disease / Protein aggregation / polvelutamine disease / folding / 蛋白質凝集 / 蛍光エネルギー共鳴 / 蛍光相関分光法 / βシート / HSP60 family / aggregation / tubulin / actin / protein folding / HSP60ファミリー / 凝集体 / チューブリン / アクチン / オートファジー / リソソーム / 遺伝子変異 / シャペロン介在性オートファジー / Lamp2a / Hsc70 / SOD1 / ALS / ATP / 機能制御 / 構造変化 / 反応サイクル / ATPase / 複合体形成 / タンパク質間相互作用 / クロスリンク / 細胞内動態 / シャペロニン / サブユニット / 細胞毒性 / タンパク凝集 … More Except Principal Investigator HSP47 / EDEM / モデル動物 / セリンプロテアーゼ / 創傷治癒学 / 組織培養 / 細胞・組織 / 再生医学 / ケロイドモデル / マトリックス / HtrA1 / 動物モデル / 創傷治癒 / ケロイド / collagen / ER mannosidase / ER associated degradation / Quality control of proteins / Molecular Chaperone / コラーゲン / 小胞体マンノシダーゼI / 小胞体関連分解 / 品質管理 / 分子シャペロン Less

Development of a new theraphy for keloids with inhibition of HtrA1 and a new keloid organ culture system
- Principal Investigator
  
  Naitoh Motoko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Institute of Physical and Chemical Research
異常タンパク質の分別輸送を介した細胞内分解機構Principal Investigator
- Principal Investigator
  
  久保田広志
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Akita University
Regulation of cellular functions by highly evolved two chaperoninsPrincipal Investigator
- Principal Investigator
  
  KUBOTA HIROSHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Akita University
凝集性異常タンパク質の脱凝集を介した細胞内分解機構Principal Investigator
- Principal Investigator
  
  久保田広志
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
ポリグルタミン凝集のダイナミクスと分子シャペロンによる毒性阻止Principal Investigator
- Principal Investigator
  
  久保田広志
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
Dynamic functions of chaperonins in the cellPrincipal Investigator
- Principal Investigator
  
  KUBOTA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Akita University
Role of CCT assisted functions in cellular activitiesPrincipal Investigator
- Principal Investigator
  
  KUBOTA Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Analysis of cellular function of the cytosolic chaperonin CCT composed of eight different subunitsPrincipal Investigator
- Principal Investigator
  
  KUBOTA Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Two novel chaperone-like proteins involved in ER quality control mechanism
- Principal Investigator
  
  NAGATA Kazuhiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY

All 2018 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 蛋白質核酸酵素53(遠藤斗志也,小椋光,永田和宏,森和俊,田口英樹,吉田賢右編)(蛋白質品質管理,CCT キーワード:蛋白質の一生)2008
- Author(s)
  久保田広志
- Publisher
  シャペロニン
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] HtrA1 Is Specifically Up-Regulated in Active Keloid Lesions and Stimulates Keloid Development.2018
- Author(s)
  Yamawaki S, Naitoh M, Kubota H, Aya R, Katayama Y, Ishiko T, Tamura T, Yoshikawa K, Enoshiri T, Ikeda M, Suzuki S.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19(5) Issue: 5 Pages: 1275-1275
- DOI
  10.3390/ijms19051275
- NAID
  120006510299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05003
[Journal Article] Regeneration of elastic fibers by three-dimensional culture on a collagen scaffold and the addition of latent TGF-β binding protein 4 to improve elastic matrix deposition.2015
- Author(s)
  Aya R, Ishiko T, Noda K, Yamawaki S, Sakamoto Y, Tomihata K, Katayama Y, Yoshikawa K, Kubota H, Nakamura T, Naitoh M, Suzuki S
- Journal Title
  
  Biomaterials
  
  Volume: 72 Pages: 29-37
- DOI
  10.1016/j.biomaterials.2015.08.036
- NAID
  120005753831
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670147, KAKENHI-PROJECT-23249078, KAKENHI-PROJECT-26440092
[Journal Article] ATPase activity and ATP-dependent conformational change in the co-chaperone HOP.2014
- Author(s)
  Yamamoto S, Subedi GP, Hanashima S, Satoh T, Otaka M, Wakui H, Sawada KI, Yokota SI, Yamaguchi Y, Kubota H, Itoh H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Issue: 14 Pages: 9880-9886
- DOI
  10.1074/jbc.m114.553255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-24770102, KAKENHI-PUBLICLY-25121730, KAKENHI-PROJECT-25860050, KAKENHI-PROJECT-26440092
[Journal Article] Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia.2014
- Author(s)
  Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi, T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  BMC Pulm. Med.
  
  Volume: 14 Issue: 1 Pages: 48-48
- DOI
  10.1186/1471-2466-14-48
- NAID
  120006986596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-25860649
[Journal Article] Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis2013
- Author(s)
  Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi. T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  Cell Stress Chaperones
  
  Volume: 18 Issue: 5 Pages: 581-590
- DOI
  10.1007/s12192-013-0411-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-23790913, KAKENHI-PROJECT-25860649
[Journal Article] Serum heat shock protein 47 levels in patients with drug-induced lung disease.2013
- Author(s)
  Kakugawa, T., Yokota, S., Ishimatsu, Y., Hayashi, T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Y., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  Respir. Res.
  
  Volume: 14 Issue: 1 Pages: 133-133
- DOI
  10.1186/1465-9921-14-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-25860649
[Journal Article] Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis.2013
- Author(s)
  Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi. T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
- Journal Title
  
  Cell Stress Chaperones
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220
[Journal Article] Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation.2013
- Author(s)
  Tashiro E, Zako T, Muto H, Itoo Y, Sorgjerd K, Terada N, Abe A, Miyazawa M, Kitamura A, Kitaura H, Kubota H, Maeda M, Momoi T, Iguchi-Ariga SM, Kinjo M, Ariga H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Issue: 27 Pages: 19958-19972
- DOI
  10.1074/jbc.m113.477984
- NAID
  120005323603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-23770215, KAKENHI-PROJECT-24570143, KAKENHI-PROJECT-24651223
[Journal Article] Multipotent stem cells are effectively collected from adult human cheek skin.2012
- Author(s)
  Yoshikawa, K., Naitoh, M., Kubota, H., Ishiko, T., Aya, R., Yamawaki, S. and Suzuki, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 431 Issue: 1 Pages: 104-110
- DOI
  10.1016/j.bbrc.2012.12.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-24791902
[Journal Article] Pirfenidone inhibits TGF-beta1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells.2012
- Author(s)
  Hisatomi, K., Mukae, H., Sakamoto, N., Ishimatsu, Y., Kakugawa, T., Hara, S., Fujita, H., Nakamichi, S., Oku, H., Urata, Y., Kubota, H., Nagata, K. and Kohno, S.
- Journal Title
  
  BMC Pulm. Med.
  
  Volume: 12 Issue: 1
- DOI
  10.1186/1471-2466-12-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570220
[Journal Article] Cytosolic chaperonin CCT possesses GTPase activity2011
- Author(s)
  Noguchi, et al
- Journal Title
  
  Am.J.Mol.Biol.
  
  Volume: 1 Issue: 03 Pages: 123-130
- DOI
  10.4236/ajmb.2011.13013
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020003, KAKENHI-PROJECT-23570220
[Journal Article] Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones2011
- Author(s)
  Kubota, et al
- Journal Title
  
  Methods
  
  Volume: 53 Pages: 267-274
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020003
[Journal Article] Protective role of the ubiquitin binding protein Tollip against the toxicity of polyglutamine-expansion proteins2011
- Author(s)
  Oguro, et al
- Journal Title
  
  Neurosci.Lett.
  
  Volume: 503 Issue: 3 Pages: 234-239
- DOI
  10.1016/j.neulet.2011.08.043
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020003, KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-23650416
[Journal Article] Analyzing the aggregation of polyglutamine-expansion proteins and itsmodulation by molecular chaperones2011
- Author(s)
  Kubota, et al
- Journal Title
  
  Methods
  
  Volume: 53 Pages: 267-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones (review).2011
- Author(s)
  Kubota H., Kitamura A., Nagata K.
- Journal Title
  
  Methods 53
  
  Pages: 267-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Fluorescently labeled proteins as a tool for analyzing the dynamics of protein quality control in living cells2010
- Author(s)
  Kubota, et al.
- Journal Title
  
  International Journal of the Society of Material Engineering and Resources 17
  
  Pages: 1-4
- NAID
  110007554333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023016
[Journal Article] Amyloid oligomers : dynamics and toxicity in the cytosol and nucleus2010
- Author(s)
  Kitamura, A., Kubota, H.
- Journal Title
  
  The FEBS Journal 277
  
  Pages: 1369-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023016
[Journal Article] Fluorescently labeled proteins as a tool for analyzing the dynamics of protein quality control in living cells.2010
- Author(s)
  Kubota H., Kitamura A., Itoh H., Kinjo M., Nagata K.
- Journal Title
  
  Int.J.Soc.Mater.Eng.Resour. 17
  
  Pages: 1-4
- NAID
  110007554333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma2010
- Author(s)
  Kubota, et al
- Journal Title
  
  Cell Stress and Chaperones
  
  Volume: 15 Pages: 1003-1011
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020003
[Journal Article] Fluorescently labeled proteins as a tool for analyzing the dynamics of protein quality control in living cells2010
- Author(s)
  Kubota, et al.
- Journal Title
  
  International Journal of the Society of Material Engineering and Resources 17
  
  Pages: 1-4
- NAID
  110007554333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Gentamicin inhibits HSP70-assisted protein folding by interfering with substrate recognition.2010
- Author(s)
  Yamamoto S., Nakano S., Owari K., Fuziwara K., Ogawa N., Otaka M., Tamaki K., Watanabe S., Komatsuda A., Wakui H., Sawada K.I., Kubota H., Itoh H.
- Journal Title
  
  FEBS Lett. 584
  
  Pages: 645-651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma2010
- Author(s)
  Kubota, et al
- Journal Title
  
  Cell Stress and Chaperones
  
  Volume: 15 Pages: 1003-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Solution structure and dynamics of mouse ARMET.2010
- Author(s)
  Hoseki J., Sasakawa H., Yamaguchi Y., Maeda M., Kubota H., Kato K., Nagata K.
- Journal Title
  
  FEBS Lett. 584
  
  Pages: 1536-1542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma.2010
- Author(s)
  Kubota H., Yamamoto S., Itoh E., Abe Y., Nakamura A., Izumi Y., Okada H., Iida M., Nanjo H., Itoh H., Yamamoto Y.
- Journal Title
  
  Cell Stress Chaperones 15
  
  Pages: 1003-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Amyloid oligomers : dynamics and toxicity in the cytosol and nucleus2010
- Author(s)
  Kitamura, A., Kubota, H.
- Journal Title
  
  The FEBS Journal 277
  
  Pages: 1369-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Amyloid oligomers : dynamics and toxicity in the cytosol and nucleus (review).2010
- Author(s)
  Kitamura A., Kubota H.
- Journal Title
  
  FEBS J. 277
  
  Pages: 1369-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Quality control against misfolded proteins in the cytosol : a network for cell survival2009
- Author(s)
  Kubota, H.
- Journal Title
  
  Journal of Biochemistry 146
  
  Pages: 609-616
- NAID
  10026304338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Quality control against misfolded proteins in the cytosol : a network for cell survival (review).2009
- Author(s)
  Kubota H.
- Journal Title
  
  J.Biochem. 146
  
  Pages: 609-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.2009
- Author(s)
  Ishida Y., Yamamoto A., Kitamura A., Lamande S.R., Yoshimori T., Bateman J.F., Kubota H., Nagata K.
- Journal Title
  
  Mol.Biol.Cell 20
  
  Pages: 2744-2754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Quality control against misfolded proteins in the cytosol : a network for cell survival2009
- Author(s)
  Kubota, H.
- Journal Title
  
  Journal of Biochemistry 146
  
  Pages: 609-616
- NAID
  10026304338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023016
[Journal Article] Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid.2009
- Author(s)
  Ikeda M., Naitoh M., Kubota H., Ishiko T., Yoshikawa K., Yamawaki S., Kurokawa M., Utani A., Nakamura T., Nagata K., Suzuki S.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 390
  
  Pages: 1221-1228
- NAID
  120001749556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Guidelines for the nomenclature of the human heat shock proteins (review).2009
- Author(s)
  Kampinga H.H., Hageman J., Vos M.J., Kubota H., Tanguay R.M., Bruford E.A., Cheetham M.E., Chen B., Hightower L.E.
- Journal Title
  
  Cell Stress Chaperones 14
  
  Pages: 105-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination.2008
- Author(s)
  Hirayama S., Yamazaki Y., Kitamura A., Oda Y., Morito D., Okawa K., Kimura H., Cyr D.M., Kubota H., Nagata K.
- Journal Title
  
  Mol.Biol.Cell 19
  
  Pages: 899-911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Cisplatin differently affects amino terminal and carboxyl terminal domains of HSP90.2008
- Author(s)
  Ishida R., Takaoka Y., Yamamoto S., Miyazaki T., Otaka M., Watanabe S., Komatsuda A., Wakui H., Sawada K., Kubota H., Itoh H.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 3879-3883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] High serum concentrations of autoantibodies to HSP47 in nonspecific interstitial pneumonia compared with idiopathic pulmonary fibrosis.2008
- Author(s)
  Kakugawa T., Yokota S., Mukae H., Kubota H., Sakamoto N., Mizunoe S., Matsuoka Y., Kadota J., Fujii N., Nagata K., Kohno S.
- Journal Title
  
  BMC Pulm.Med. 8
  
  Pages: 23-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570182
[Journal Article] Cytosolic chaperonin protects folding intermediates of Gβ from aggregation by recognizing hydrophobic β-strands2006
- Author(s)
  Kubota et al.
- Journal Title
  
  The Proceeding of the National Academy of Sciences of the United States of America 103・22
  
  Pages: 8360-8365
- Data Source
  KAKENHI-PROJECT-18570175
[Journal Article] Cytosolic chaperonin protects folding intermediates of Gβ from aggregation by recognizing hydrophobic β-strands2006
- Author(s)
  Kubota, et. al.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 103
  
  Pages: 8360-8365
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570175
[Presentation] α-Synucleinのエキソソームによる細胞間伝達メカニズムの解析2015
- Author(s)
  佐藤晶子、佐藤望、加藤渚、齋藤彩夏、久保田広志、田村拓
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440092
[Presentation] Lysosome-dependent degradation of ALS-linked mutant SOD12013
- Author(s)
  Daisuke Yamada, Taku Tamura, Hiroshi Kubota
- Organizer
  International Mini-symposium: Protein Folding and Disease
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Actin and myosin participate in the quality control of SOD1 aggregates2013
- Author(s)
  Taku Tamura, Akihiko Yatabe, Koji Ichinohe, Yuko Shimizu, Akira Kitamura, Masataka Kinjo, Hiroshi Kubota
- Organizer
  International Mini-symposium: Protein Folding and Disease
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] アクチン・ミオシン系は筋萎縮性側索硬化症原因タンパク質SOD1変異体の凝集制御および分解に関与する2013
- Author(s)
  田村拓, 矢田部暁彦, 一戸康治, 清水佑子, 北村朗, 金城政孝, 久保田広志
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Lysosome-dependent degradation of ALS-linked mutant SOD12013
- Author(s)
  Daisuke Yamada, Taku Tamura, Hiroshi Kubota
- Organizer
  International Mini-symposium Protein Folding and Disease
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Actin and myosin participate in the quality control of SOD1 aggregates2013
- Author(s)
  Taku Tamura, Akihiko Yatabe, Koji Ichinohe, Yuko Shimizu, Akira Kitamura, Masataka Kinjo, Hiroshi Kubota
- Organizer
  International Mini-symposium Protein Folding and Disease
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Aminoglycoside antibiotics suppress the Heat Shock Protein 70 function2013
- Author(s)
  Yamamoto, S., Yokota, S., Wakui, H., Kubota, H., Itoh, H, and Fujii, N.
- Organizer
  28th International Congress of Chemotherapy and Infection
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] 筋萎縮性側索硬化症原因タンパク質SOD1変異体のリソソーム依存的分解2013
- Author(s)
  田村拓、山田大介、久保田広志
- Organizer
  第８回臨床ストレス応答学会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] 筋萎縮性側索硬化症原因タンパク質SOD変異体のリソソーム依存的分解2013
- Author(s)
  田村拓, 山田大介, 久保田広志
- Organizer
  第8回臨床ストレス応答学会
- Place of Presentation
  松本市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Aminoglycoside antibiotics suppress the Heat Shock Protein 70 function.2013
- Author(s)
  Yamamoto S, Yokota S, Wakui H, Kubota H, Itoh H, Fujii N
- Organizer
  28th International Congress of Chemotherapy and Infection
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Serine Protease-Family Protein HtrA1 is Specifically Up-regulated in Keloid Legions2012
- Author(s)
  Motoko Naitoh, Toshihiro Ishiko, Satoko Yamawaki, Taku Tamura, Rino Aya, Katsuhiro Yoshikawa, Hiroshi Kubota and Shigehiko Suzuki.
- Organizer
  第4回世界創傷治癒学会連合会議(WUWHS 2012)
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] Serine Protease-Family Protein HtrA1 is Specifically Up-regulated in Keloid Legions2012
- Author(s)
  Motoko Naitoh, Toshihiro Ishiko, Satoko Yamawaki, Taku Tamura, Rino Aya, Katsuhiro Yoshikawa, Hiroshi Kubota and Shigehiko Suzuki.
- Organizer
  第4回世界創傷治癒学会連合会議（WUWHS 2012）
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] 筋萎縮性側索硬化症原因タンパク質SOD1変異体の凝集制御および分解おけるアクチンフィラメントの役割2012
- Author(s)
  田村拓, 矢田部暁彦, 一戸康児, 清水佑子, 北村朗, 金城政孝, 久保田広志
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] シャペロニンHsp60のATP、Hsp10依存的なダブルリング化について2011
- Author(s)
  石田竜一, 久保田広志, 高橋弘樹, 岡俊, 北村朗, 金城政孝, 伊藤英晃
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23570220
[Presentation] 免疫抑制剤MizoribineによるHSP60阻害機構の解明2010
- Author(s)
  田名邉雅子、宮崎敏夫、石田竜一、高橋弘樹、久保田広志、伊藤英晃
- Organizer
  第5回臨床ストレス応答学会
- Place of Presentation
  徳島市(口頭発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Formation of HOP-containing chaperone complexes and the effect of 17-AAG, an HSP90 inhibitor, on colon cancer cells.2010
- Author(s)
  Hiroshi Kubota, Soh Yamamoto, Yuzo Yamamoto, Hideaki Itoh
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Molecular chaperone prefoldin blocks the formation of mutant Huntingtin oligomer and inclusion body, resulting in reduction of its Cytotoxity.2010
- Author(s)
  Erika Tashiro, Hideki Muto, Tamotsu Zako, Makoto Miyazawa, Hirotake Kitaura, Akira Kitamura, Hiroshi Kubota, Mizuo Maeda, Masataka Kinjo, Hiroyoshi Ariga
- Organizer
  40th Annual Meeting of the Society for Neuroscience (Neuroscience 2010)
- Place of Presentation
  San Diego(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] ポリグルタミンタンパク質凝集における分子シャペロンプレフォルディンの役割2010
- Author(s)
  伊藤禎宣、座古保、ソルヤード・カリン、寺田尚史、田代絵梨佳、北村朗、久保田広志、武藤秀樹、金城政孝、有賀寛芳、前田瑞夫
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Co-chaperone HOP (HSP70/HSP90 organizing protein) has ATPase activity and changes its conformation in the presence of ATP.2010
- Author(s)
  Soh Yamamoto, Ganesh Prasad Subedi, Shinya Hanashima, Tadashi Satoh, Yoshiki Yamaguchi, Hiroshi Kubota, Hideaki Itoh
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 分子シャペロンPrefoldinはポリグルタミンの凝集と細胞毒性を減少させる2010
- Author(s)
  田代絵梨佳,武藤秀樹,座古保,宮澤誠,北浦廣剛,北村朗,久保田広志,前田瑞夫,金城政孝,有賀寛芳
- Organizer
  第33回日本神経科学大会-第53回日本神経化学会大会-第20回日本神経回路学会大会-合同大会
- Place of Presentation
  神戸市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Formation of HOP-containing chaperone complexes and the effect of 17-AAG, an HSP90 inhibitor, on colon cancer cells2010
- Author(s)
  Kubota, et al
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PUBLICLY-22020003
[Presentation] 筋萎縮性側索硬化症を引き起こす原因タンパク質の脱凝集過程と細胞毒性の関係性2010
- Author(s)
  北村朗,稲田のりこ,久保田広志,松本弦,永田和宏,金城政孝
- Organizer
  第33回日本分子生物学会年会-第83回日本生化学会大会-合同大会
- Place of Presentation
  神戸市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 分子シャペロンPrefoldinは変異ハンチンチンのオリゴマーおよび凝集形成を阻害して細胞死を減少させる2010
- Author(s)
  田代絵梨佳、武藤秀樹、座古保、ソルヤード・カリン、宮沢誠、北浦廣剛、北村朗、久保田広志、前田瑞夫、金城政孝、有賀寛芳
- Organizer
  第33回日本分子生物学会年会-第83 回日本生化学会大会-合同大会
- Place of Presentation
  神戸市(口頭発表およびポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 蛍光で見る蛋白質品質管理のダイナミクス2010
- Author(s)
  久保田広志
- Organizer
  平成22年度日本分析化学会東北支部若手交流会
- Place of Presentation
  秋田市(口頭発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Formation of HOP-containing chaperone complexes and the effect of 17-AAG, an HSP90 inhibitor, on colon cancer cells2010
- Author(s)
  Kubota, et al
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] ATP-dependent transition of Hsp60 from single to double rings in the presence of cochaperonin Hsp10.2010
- Author(s)
  Ryuichi Ishida, Toshihiko Oka, Hiroki Takahashi, Hiroshi Kubota, Hideaki Itoh
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  奈良市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Aggregation and disaggregation of ALS-linked mutant SOD1 via soluble oligomers in living cells.2009
- Author(s)
  Hiroshi Kubota, Akira Kitamura, Noriko Inada, Gen Matsumoto, Richard Morimoto, Masataka Kinjo, Kazuhiro Nagata
- Organizer
  第61回日本細胞生物学会大会シンポジウム「タンパク質社会と品質管理」
- Place of Presentation
  名古屋市(口頭発表)
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] SOD1脱凝集過程におけるタンパク質分解経路と細胞毒性の関係について2009
- Author(s)
  北村朗,稲田のりこ,久保田広志,松本弦,Richard I.Morimoto,金城政孝,永田和宏
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜市(口頭発表およびポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Fluorescently labeled proteins as a tool for analyzing the dynamics of protein quality control in living cells2009
- Author(s)
  Kubota, et al.
- Organizer
  the 6th Conference on Materials Engineering for Resources
- Place of Presentation
  秋田市
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20023016
[Presentation] Cisplatin differently affects amino terminal amd carboxyl terminal domains of HSP90.2009
- Author(s)
  Ryuichi Ishida, Yuka Takaoka, Soh Yamamoto, Toshio Miyazaki, Michiro Otaka, Sumio Watanabe, Atushi Komatsuda, Hideki Wakui, Ken-ichi Sawada, Hiroshi Kubota, Hideaki Itoh
- Organizer
  The 4th International Congress on Stress Responses in Biology and Medicine.
- Place of Presentation
  札幌市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] タンパク質品質管理機構の研究2009
- Author(s)
  久保田広志
- Organizer
  平成20年度京都大学再生医科学研究所共同研究会
- Place of Presentation
  京都市(口頭発表)
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] ミトコンドリア移行シグナル付加Hsp60の生理機能解析2009
- Author(s)
  石田竜一、伊豆原史子、関根和宏、大高慶、久保田広志、伊藤英晃
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Fluorescently labeled proteins as a tool for analyzing the dynamics of protein quality control in living cells.2009
- Author(s)
  Hiroshi Kubota, Akira Kitamura, Hideaki Itoh, Masataka Kinjo, Kazuhiro Nagata
- Organizer
  The Sixth Conference on Materials Engineering for Resources. Keynote session 'New Materials for Life Science-I'(Abstracts, p12)
- Place of Presentation
  秋田市(口頭発表)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Fluorescently labeled proteins as a tool for analyzing the dynamics of protein quality control in living cells2009
- Author(s)
  Kubota, et al.
- Organizer
  The 6th Conference on Materials Engineering for Resources
- Place of Presentation
  秋田市
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Increased expression of HOP and chaperone complex formation in human colonic carcinoma.2009
- Author(s)
  Hiroshi Kubota, Soh Yamamoto, Yuzo Yamamoto, Hideaki Itoh
- Organizer
  The 4th International Congress on Stress Responses in Biology and Medicine. Workshop 'Stress Responses in Disease'(Abstracts, p169)
- Place of Presentation
  札幌市(口頭発表およびポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Aggregation and disaggregation of ALS-linked mutant SOD1 via soluble oligomers in living cells2009
- Author(s)
  Kubota, et al.
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋市
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Aggregation and disaggregation of ALS-linked mutant SOD1 via soluble oligomers in living cells2009
- Author(s)
  Kubota, et al.
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋市
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20023016
[Presentation] Gravity-responsive transcriptional regulation of collagen-specific molecular chaperone HSP47.2009
- Author(s)
  Asami Oguro-Ando, Hiroshi Kubota, Yoriko Atomi, Shoichi Ishiura, Kazuhiro Nagata
- Organizer
  日本宇宙生物科学会第23回大会
- Place of Presentation
  つくば市(口頭発表)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Increased expression of HOP and chaperone complex formation in human colonic carcinoma2009
- Author(s)
  Kubota, et al.
- Organizer
  The 4th International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Dynamics of Aggregation and disaggregation of neurodegenerative disease-causative proteins2009
- Author(s)
  Akira Kitamura, Masataka Kinjo, Hiroshi Kubota, Kazuhiro Nagata
- Organizer
  International Conference 'Protein folding and neurodegenerative disease'
- Place of Presentation
  京都市(口頭発表)
- Year and Date
  2009-04-06
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] MM-1およびPrefoldinがポリグルタミン凝集に与える影響2009
- Author(s)
  田代絵梨佳,武藤秀樹,座古誠,宮澤誠,北浦廣剛,北村朗,久保田広志,前田瑞夫,金城正孝,有賀芳寛
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] The antibiotic gentamicin (GM) was specifically bound to HSP70 C-domain and inhibited HSP40/HSC70 chaperone activity.2009
- Author(s)
  Soh Yamamoto, Shunsuke Nakano, Hiroshi Kubota, Hideaki Itoh
- Organizer
  The 4th International Congress on Stress Responses in Biology and Medicine.
- Place of Presentation
  札幌市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Increased expression of HOP and chaperone complex formation in human colonic carcinoma2009
- Author(s)
  Kubota, et al.
- Organizer
  The 4th International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-20023016
[Presentation] Autophagy eliminates misfolded procollagen aggregates in the endoplasmic reticulum for cell survival.2009
- Author(s)
  Yoshihito Ishida, Akitsugu Yamamoto, Akira Kitamura, Shireen R.Lamande, Tamotsu Yoshimori, John F.Bateman, Hiroshi Kubota, Kazuhiro Nagata
- Organizer
  Joint meeting of 8th Pan-Pacific Connective Tissue Societies Symposium (PPCTSS), 41st Annual Meeting of the Japanese Society of Connective Tissue Research (JSCTR), and 56th Annual Meeting of the Japan Matrix Club.
- Place of Presentation
  横須賀市(ポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 小胞体に蓄積した変異コラーゲンの分解:オートファジーとERADの使い分け2008
- Author(s)
  石田義人、久保田広志、北村朗、山本章嗣、John Bateman、吉森保、永田和宏
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市(一般口頭発表およびポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 哺乳類Hsp60の生化学的性質の解析2008
- Author(s)
  関根和宏,石田竜一,野口晋,山本聡,大高慶,伊豆原史子,涌井秀樹,澤田賢一,大高道郎,久保田広志,伊藤英晃
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Misfolded collagens acumulated in the ER by the absence of HSP47 are disposed via autophagy-lysosome.2008
- Author(s)
  Yoshihito Ishida, Akitsugu Yamamoto, Akira Kitamura, Tamotsu Yoshimori, John F.Bateman, Hiroshi Kubota, Kazuhiro Nagata
- Organizer
  Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
- Place of Presentation
  Cold Spring Harbor (USA)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 大腸菌多機能プロテアーゼ/シャペロンHtrA/DegPのヒトホモローグの一つHteA1の発現はケロイドの病期と予後に相関する2008
- Author(s)
  内藤素子、久保田広志、石河利弘、吉川勝宇、山脇聖子、鈴木茂彦、永田和宏
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] GGAはヘリコバクターピロリ菌dnaK(HSP70)のシャペロン活性を選択的に抑制する2008
- Author(s)
  大瀧貴子,山本聡,藤原一彦,小熊恵二,佐藤昇志,大高道郎,久保田広志,伊藤英晃
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] コシャペロンHOPとAnnexinA2の相互作用解析2008
- Author(s)
  尾張健介、山本聡、湧井秀樹、澤田賢一、小林良二、久保田広志、伊藤英晃
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] HOP ATPase活性の分子シャペロン複合体に及ぼす影響2008
- Author(s)
  山本聡、藤原一彦、涌井秀樹、山本雄造、大高道郎、久保田広志、伊藤英晃
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 小胞体に蓄積するミスフォールドコラーゲンの構造依存的な分解経路の仕分け2008
- Author(s)
  石田義人、山本章嗣、北村朗、Shireen R Lamande、吉森保、John F Bateman、久保田広志、永田和宏
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 分光イメージング法を用いた変異型SOD1の凝集体形成と凝集体中間構造の解析-凝集中間体と細胞毒性の関係について-2008
- Author(s)
  北村朗、久保田広志、稲田のりこ、松本弦、Richard I.Morimoto、金城政孝、永田和宏
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会-合同大会
- Place of Presentation
  神戸市(一般口頭発表およびポスター発表)
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] Gentamicin誘導腎毒性に対するHSP70の抵抗性2008
- Author(s)
  伊藤江里、山本聡、宮崎敏夫、小松敦、涌井秀樹、澤田賢一、大高道郎、久保田広志、伊藤英晃
- Organizer
  第3回臨床ストレス応答学会大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20570182
[Presentation] 細胞質シャペロニンCCTはタンパク質凝集を防ぐことにより細胞を守る2007
- Author(s)
  久保田広志, 他
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡市
- Year and Date
  2007-05-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570175
[Presentation] Role of cytosolic chaperonin CCT in preventing the cytotoxicity of aggregation prone proteins2007
- Author(s)
  Kubota, et. al.
- Organizer
  Joint meeting of the 40th JSDB and 59th JSCB annual meetings
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2007-05-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570175
[Presentation] McKusick-Kaufman syndromeタンパク質の病因変異体の凝集と分解2007
- Author(s)
  久保田広志, 他
- Organizer
  第2回臨床ストレス応答学会大会
- Place of Presentation
  福岡市
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-18570175
[Presentation] 細胞質シャペロニンCCT共役因子の探索2007
- Author(s)
  久保田広志, 他
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18570175
[Presentation] 筋萎縮性側索硬化症原因タンパク質SOD1の脱凝集過程の解析
- Author(s)
  勝木莉子、田村拓、北村朗、金城政孝、久保田広志
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26440092
[Presentation] 異常タンパク質の細胞内における脱凝集過程の解析
- Author(s)
  勝木莉子、田村拓、北村朗、金城政孝、久保田広志
- Organizer
  第9回ストレス応答学会大会
- Place of Presentation
  岡山市
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26440092

1. NAGATA Kazuhiro (50127114)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. KINJO Masataka (70177971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. KITAMURA Akira (10580152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. Naitoh Motoko (30378723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SUZUKI Shigehiko (30187728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 江野尻竜樹 (00748270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 山脇聖子 (70378777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 吉川勝宇 (10583156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 中邨智之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUBOTA Hiroshi 久保田 広志

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Development of a new theraphy for keloids with inhibition of HtrA1 and a new keloid organ culture system

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異常タンパク質の分別輸送を介した細胞内分解機構Principal Investigator

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Regulation of cellular functions by highly evolved two chaperoninsPrincipal Investigator

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凝集性異常タンパク質の脱凝集を介した細胞内分解機構Principal Investigator

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ポリグルタミン凝集のダイナミクスと分子シャペロンによる毒性阻止Principal Investigator

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Dynamic functions of chaperonins in the cellPrincipal Investigator

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Role of CCT assisted functions in cellular activitiesPrincipal Investigator

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Analysis of cellular function of the cytosolic chaperonin CCT composed of eight different subunitsPrincipal Investigator

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Two novel chaperone-like proteins involved in ER quality control mechanism

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[Book] 蛋白質核酸酵素53(遠藤斗志也,小椋光,永田和宏,森和俊,田口英樹,吉田賢右編)(蛋白質品質管理,CCT キーワード:蛋白質の一生)2008

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[Journal Article] HtrA1 Is Specifically Up-Regulated in Active Keloid Lesions and Stimulates Keloid Development.2018

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[Journal Article] Regeneration of elastic fibers by three-dimensional culture on a collagen scaffold and the addition of latent TGF-β binding protein 4 to improve elastic matrix deposition.2015

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NAID

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[Journal Article] ATPase activity and ATP-dependent conformational change in the co-chaperone HOP.2014

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[Journal Article] Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia.2014

KUBOTA Hiroshi 久保田広志