HIROTSUNE Shinji 広常真治

… Alternative Names

広常真治ヒロツネシンジ

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Researcher Number	80337526
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 大阪公立大学, 大学院医学研究科, 教授 2023: 大阪公立大学, 大学院医学研究科, 教授 2015 – 2019: 大阪市立大学, 大学院医学研究科, 教授 2016: 大阪市立大学, 医学研究科, 教授 2012 – 2014: 大阪市立大学, 医学(系)研究科(研究院), 教授 … More 2007 – 2012: Osaka City University, 大学院・医学研究科, 教授 2005 – 2006: 大阪市立大学, 大学院医学研究科, 教授 2003 – 2004: 大阪市立大学, 大学院・医学研究科, 教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Biological Sciences / General medical chemistry / Basic Section 49010:Pathological biochemistry-related / Developmental biology / Complex systems Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields / General medical chemistry / Biological Sciences
Keywords	Principal Investigator 細胞質ダイニン / モータータンパク質 / 染色体分離 / 神経細胞 / LIS1 / 紡錘体形成 / 中枢神経系 / 細胞骨格 / 微小管 / 細胞周期 … More / 細胞内物質輸送 / 発がん / 染色体分配 / 中心体 / Wnt / 神経科学 / 神経変性疾患 / 細胞間接着・細胞極性 / 中胚葉分化 / 神経発生 / Transcription / Mesoderm induction / Cadherin / Cell adhesion, Cell polarity / 発生学 / 細胞極性 / Wntシグナル / 転写調節 / カドヘリン / 細胞間接着 / キネシン / 細胞内骨格 / 脳・神経細胞 / 遺伝子 / 脳神経疾患 / 神経化学 / モータータンパンク質 / 神経細胞遊走 / 先天性神経疾患 / 低分子量G蛋白質 / 構造解析 / アイドリング状態 / 微小管複合体 / 微小管ネットワーク / 分化終末細胞 / mitotic kinase / 治療 / 滑脳症 / 阻害剤 / カルパイン / 滑脳症治療 / 脳機能 / 軸索伸展 / 細胞分裂 / (B)細胞医化学 / M-期 / 紡錘体制御 / PP4 / 核膜崩壊 / リン酸化 / Lamin B / カタニン / ダイニン / 多発性嚢胞腎 / nc-RNA / 偽遺伝子 / 転写後遺伝子調節 / 進化 … More Except Principal Investigator パーキンソン病 / 滑脳症・小脳症 / 神経幹細胞の増殖 / 神経細胞の遊走 / 神経幹細胞の分裂 / microlissencephaly / α-Synuclein / 微小管ネットワーク / NuMA / 細胞質ダイニン / カタニンp80 / 中枢神経形成不全 / 発現制御 / 発生・分化 / 発生制御 / 細胞・組織 / シグナル因子 / 中心体 / 繊毛 Less

新規モデルマウスを用いた機能喪失の観点からのアルツハイマー病の病態生理の解明Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Osaka Metropolitan University
前駆期パーキンソン病をターゲットとした病態解明と疾患修飾療法の開発
- Principal Investigator
  
  高橋良輔
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kyoto University
Explore of unconventional microtubulesPrincipal Investigator
- Principal Investigator
  
  Hirotsune Shinji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
Clarify the pathogenic mechnism of microlissencephaly
- Principal Investigator
  
  Jin Mingyue
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
神経疾患における細胞内輸送の障害:細胞質ダイニンの制御と破綻Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
Explore of roles of the centrosome in neurogenesisPrincipal Investigator
- Principal Investigator
  
  Hirotsune Shinji
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
Cilium-centrosome system regulating biosignal flows
- Principal Investigator
  
  Hamada Hiroshi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
  Osaka University
増殖と分化のスイッチング:細胞周期制御因子の非分裂細胞における新たな役割の解明Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
細胞質ダイニンのアイドリング複合体の構造解析と活性化メカニズムの解明Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka City University
滑脳症治療への挑戦:カルパインによるリスワン分解機構の解明Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
染色体分配の異常と発がん:細胞分裂におけるダイニン、微小管の制御機構の解明。Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
増殖と分化のスイッチング:神経細胞における細胞周期制御の解明。Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
Elucidation of regulatory mechanisms of cytoplasmic dynein.Principal Investigator
- Principal Investigator
  
  HIROTSUNE Shinji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
染色体分離機構の破綻と疾患:ダイニンと微小管ネットワークの制御機構の解明Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
核膜崩壊の前夜:M期突入に伴う核内物質移動のダイナミズムPrincipal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
疾患原因の探究のための偽遺伝子のゲノム資源としての活用Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
M期における核膜崩壊と紡錘体形成を制御するモータータンパクの調節機構の解明Principal Investigator
- Principal Investigator
  
  広常真治
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
Regulation of cadherin by a novel protein carring the RING finger motif via β-cateninPrincipal Investigator
- Principal Investigator
  
  HIROTSUNE Shinji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Osaka City University

All 2020 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation

[Journal Article] Enhanced homologous recombination by the modulation of targeting vector ends2020
- Author(s)
  Shinji Hirotsune, Hiroshi Kiyonari、Mingyue Jin, Kanako Kumamoto, Kayo Yoshida, Miki Shinohara, Hitomi Watanabe, Anthony Wynshaw-Boris, Fumio Matsuzaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 58893-58899
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04047
[Journal Article] Developmental downregulation of LIS1 expression limits axonal extension and allows axon pruning2017
- Author(s)
  Kumamoto Kanako、Iguchi Tokuichi、Ishida Ryuichi、Uemura Takuya、Sato Makoto、Hirotsune Shinji
- Journal Title
  
  Biology Open
  
  Volume: 6 Pages: 1041-1055
- DOI
  10.1242/bio.025999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04014, KAKENHI-PROJECT-17H04047
[Journal Article] Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport2017
- Author(s)
  Toba Shiori、Jin Mingyue、Yamada Masami、Kumamoto Kanako、Matsumoto Sakiko、Yasunaga Takuo、Fukunaga Yuko、Miyazawa Atsuo、Fujita Sakiko、Itoh Kyoko、Fushiki Shinji、Kojima Hiroaki、Wanibuchi Hideki、Arai Yoshiyuki、Nagai Takeharu、Hirotsune Shinji
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 16386-16386
- DOI
  10.1038/s41598-017-15575-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09162, KAKENHI-PROJECT-17K15603, KAKENHI-PROJECT-17H04047, KAKENHI-PROJECT-15K08283
[Journal Article] Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics2017
- Author(s)
  Jin M., Pomp O., Shinoda T., Toba S., Torisawa T., Furuta K., Oiwa K., Yasunaga T., Kitagawa D., Matsumura S., Miyata T., Tan T., Reversade B. and Hirotsune S.
- Journal Title
  
  Scientific Reports
  
  Volume: 7
- NAID
  120005997787
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08283
[Journal Article] Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics2017
- Author(s)
  Mingyue Jin, Oz Pomp, Tomoyasu Shinoda, Shiori Toba, Takayuki Torisawa, Ken’ya Furuta, Kazuhiro Oiwa, Takuo Yasunaga, Daiju Kitagawa, Shigeru Matsumura, Takaki Miyata, Thong Teck Tan, Bruno Reversade & Shinji Hirotsune
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 39902-39902
- DOI
  10.1038/srep39902
- NAID
  120005997787
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01325, KAKENHI-PUBLICLY-15H01644, KAKENHI-PLANNED-24113007, KAKENHI-PROJECT-16H06168, KAKENHI-PROJECT-26440089, KAKENHI-PROJECT-15K18953, KAKENHI-PROJECT-15K08282, KAKENHI-PROJECT-16H06280, KAKENHI-PUBLICLY-15H01213, KAKENHI-PROJECT-16H02457, KAKENHI-PROJECT-17H04047
[Journal Article] Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway.2016
- Author(s)
  Inaba H, Goto H, Kasahara K, Kumamoto K, Yonemura S, Inoko A, Yamano S, Wanibuchi H, He D, Goshima N, Kiyono T, Hirotsune S, Inagaki M.
- Journal Title
  
  J Cell Biol.
  
  Volume: 212 Issue: 4 Pages: 409-423
- DOI
  10.1083/jcb.201507046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-15K08324, KAKENHI-PROJECT-26340042, KAKENHI-PROJECT-26440111, KAKENHI-ORGANIZER-24113001, KAKENHI-PLANNED-24113005, KAKENHI-PLANNED-24113007, KAKENHI-PROJECT-25460089, KAKENHI-PROJECT-26650071, KAKENHI-PROJECT-15K20105, KAKENHI-PROJECT-15H02398
[Journal Article] Developmental Alcohol Exposure Impairs Activity-Dependent S-Nitrosylation of NDEL1 for Neuronal Maturation.2016
- Author(s)
  Saito A, Taniguchi Y, Kim SH, Selvakumar B, Perez G, Ballinger MD, Zhu X, Sabra J, Jallow M, Yan P, Ito K, Rajendran S, Hirotsune S, Wynshaw-Boris A, Snyder SH, Sawa A, Kamiya A.
- Journal Title
  
  Cereb Cortex.
  
  Volume: -
- DOI
  10.1093/cercor/bhw201
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24113007
[Journal Article] DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation.2015
- Author(s)
  1.Okamoto, M., Iguchi, T., Hattori, T., Matsuzaki, S., Koyama, Y., Taniguchi, M., Kodama, M., Xie, M-J., Yagi, H., Shimizu, S., Konishi, Y., Yoshimi, T., Tachibana, T., Fujieda, S., Katayama, T., Ito, A., Hirotsune, S., Tohyaman, M. and Sato, M.
- Journal Title
  
  J Neurosci
  
  Volume: 18 Issue: 7 Pages: 2942-2958
- DOI
  10.1523/jneurosci.5029-13.2015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24113007, KAKENHI-PROJECT-25293043, KAKENHI-PROJECT-25670091, KAKENHI-PROJECT-26430017, KAKENHI-PROJECT-26430036, KAKENHI-PROJECT-15K06790, KAKENHI-PROJECT-15K08151, KAKENHI-PROJECT-26460258
[Journal Article] Lis1 restricts the conformational changes in cytoplasmic dynein on microtubules.2015
- Author(s)
  Toba S, Koyasako K, Yasunaga Y, Hirotsune S
- Journal Title
  
  Microscopy
  
  Volume: 64 Issue: 6 Pages: 419-427
- DOI
  10.1093/jmicro/dfv055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08282, KAKENHI-PLANNED-24113007
[Journal Article] Arl3 and LC8 regulate dissociation of dynactin from dynein.2014
- Author(s)
  Jin M, Yamada M, Arai Y, Nagai T, Hirotsune S.
- Journal Title
  
  Nat Commun.
  
  Volume: 5 Issue: 1 Pages: 5295-5295
- DOI
  10.1038/ncomms6295
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24113007, KAKENHI-PROJECT-26293066
[Journal Article] Post-natal therapeutic intervention for lissencephaly using a blood-brain-barrier permeable calpain inhibitor2013
- Author(s)
  Shiori Toba, Yasuhisa Tamura, Kanako Kumamoto, Masami Yamada, Keizo Takao, Satoko Hattori, Tsuyoshi Miyakawa, Yosky Kataoka, Mitsuyoshi Azuma, Kiyoshi Hayasaka, Masano Amamoto, Keiko Tominaga, Anthony Wynshaw-Boris, Mitsuhiro Kato and Shinji Hirotsune
- Journal Title
  
  SNJ1945 Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 1224-1224
- DOI
  10.1038/srep01224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390056, KAKENHI-PROJECT-23659092, KAKENHI-PUBLICLY-24111546, KAKENHI-PROJECT-24700352, KAKENHI-PUBLICLY-25123704, KAKENHI-PROJECT-25460399, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23113723, KAKENHI-PLANNED-24113007
[Journal Article] Activation of Aurora-A is essential for neuronal migration via modulation of microtubule organization.2013
- Author(s)
  Takitoh T, Kumamoto K, Wang CC, Sato M, Toba S, Wynshaw-Boris A, Hirotsune S
- Journal Title
  
  J Neurosci
  
  Volume: 32 Pages: 11020-66
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24113007
[Journal Article] Kinesin-1 regulates dendrite microtubule polarity in Caenorhabditis elegans2013
- Author(s)
  Jing Yan
- Journal Title
  
  eLIFE
  
  Volume: 2
- DOI
  10.7554/elife.00133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657075, KAKENHI-PLANNED-24113007
[Journal Article] Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement.2013
- Author(s)
  Yamada M, Kumamoto K, Mikuni S, Arai Y, Kinjo M, Nagai T, Tsukasaki Y, Watanabe TM, Fukui M, Jin M, Toba S, Hirotsune S.
- Journal Title
  
  Nat Commun.
  
  Volume: 4:2033 Issue: 1 Pages: 2033-2033
- DOI
  10.1038/ncomms3033
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23115003, KAKENHI-PROJECT-23770168, KAKENHI-PLANNED-24113007
[Journal Article] Calpain inhibition rescues an in vitro excitatory synaptic transmission deficit in Lis1 mutant mice2013
- Author(s)
  Sebe, J., Bershteyn, M., Hirotsune. S. Wynshaw-Boris, A., Baraban, S.
- Journal Title
  
  J Neurophysiol.
  
  Volume: (in press) Issue: 2 Pages: 429-36
- DOI
  10.1152/jn.00431.2012
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111541, KAKENHI-PLANNED-24113007
[Journal Article] The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex.2013
- Author(s)
  Xie. Y., Jueschke, C., Esk, C., Hirotsune S. and Knoblich, Y.
- Journal Title
  
  Neuron
  
  Volume: 24 Issue: 2 Pages: 254-265
- DOI
  10.1016/j.neuron.2013.05.027
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24113007
[Journal Article] Activation of Aurora-A is Essential for Neuronal Migration via Modulation of Microtubule Organization2012
- Author(s)
  Takako Takitoh, Kanako Kumamoto, Chen-Chi Wang, Makoto Sato, Shiori Toba, Anthony Wynshaw-Boris, Shinji Hirotsune
- Journal Title
  
  Journal of Neuroscience
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121518
[Journal Article] A unique role of dynein and nud family proteins in corticogenesis2012
- Author(s)
  Toba S, Hirotsune S
- Journal Title
  
  Neuropathology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019031
[Journal Article] Activation of Aurora-A is essential for neuronal migration via modulation of microtubule organization.2012
- Author(s)
  Takitoh, T. et al.
- Journal Title
  
  J. Neurosci.
  
  Volume: 32(32) Issue: 32 Pages: 11050-11066
- DOI
  10.1523/jneurosci.5664-11.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659092, KAKENHI-PUBLICLY-24111541
[Journal Article] Activation of Aurora-A is Essential for Neuronal Migration via Modulation of Microtubule Organization2012
- Author(s)
  Takako Takitoh, Kanako Kumamoto, Chen-Chi Wang, Makoto Sato, Shiori Toba, Anthony Wynshaw-Boris, Shinji Hirotsune
- Journal Title
  
  Journal of Neuroscience
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019031
[Journal Article] A unique role of dynein and nud family proteins in corticogenesis2012
- Author(s)
  Toba S, Hirotsune S
- Journal Title
  
  Neuropathology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121518
[Journal Article] Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein2011
- Author(s)
  Ibi, M., Zou, P., Inoko, A., Shiromizu, T., Matsuyama, M., Hayashi, Y., Enomoto, M., Mori, D., Hirotsune, S., Kiyono, T., Tsukita, S., Goto, H., Inagaki, M.
- Journal Title
  
  J Cell Sci
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.2011
- Author(s)
  Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork NJ, Wynshaw-Boris A.
- Journal Title
  
  PLoS Genet.
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019031
[Journal Article] Functional dissection of LIS1 and NDEL1 towards understanding the molecular mechanisms of cytoplasmic dynein regulation2011
- Author(s)
  Torisawa, T., Nakayama, A., Furuta, K., Yamada, M., Hirotsune, S., Toyoshima, Y. Y.
- Journal Title
  
  J Biol Chem 286
  
  Pages: 1959-1965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] Functional dissection of LIS1 and NDEL1 towards understanding the molecular mechanisms of cytoplasmic dynein regulation.2011
- Author(s)
  Torisawa T, Nakayama A, Furuta K, Yamada M, Hirotsune S, Toyoshima YY.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 1954-1965
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025028
[Journal Article] Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.2011
- Author(s)
  Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork NJ, Wynshaw-Boris A.
- Journal Title
  
  PLoS Genet.
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121518
[Journal Article] Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.2011
- Author(s)
  Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M.
- Journal Title
  
  J Cell Sci.
  
  Volume: 124 Pages: 857-864
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019031
[Journal Article] Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects2011
- Author(s)
  Pramparo, T., Libiger, O., Jain, S., Li, H., Youn, Y. H., Hirotsune, S., Schork, N. J., Wynshaw-Boris, A.
- Journal Title
  
  PLoS Genet 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] Functional dissection of LIS1 and NDEL1 towards understanding the molecular mechanisms of cytoplasmic dynein regulation.2011
- Author(s)
  Torisawa T, Nakayama A, Furuta K, Yamada M, Hirotsune S, Toyoshima YY.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 1954-1965
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121518
[Journal Article] Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.2011
- Author(s)
  Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M.
- Journal Title
  
  J Cell Sci.
  
  Volume: 124 Pages: 857-864
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025028
[Journal Article] Functional dissection of LIS1 and NDEL1 towards understanding the molecular mechanisms of cytoplasmic dynein regulation.2011
- Author(s)
  Torisawa T, Nakayama A, Furuta K, Yamada M, Hirotsune S, Toyoshima YY.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 1954-1965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.2011
- Author(s)
  Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork NJ, Wynshaw-Boris A.
- Journal Title
  
  PLoS Genet.
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025028
[Journal Article] Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.2011
- Author(s)
  Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork NJ, Wynshaw-Boris A.
- Journal Title
  
  PLoS Genet.
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] Functional dissection of LIS1 and NDEL1 towards understanding the molecular mechanisms of cytoplasmic dynein regulation.2011
- Author(s)
  Torisawa T, Nakayama A, Furuta K, Yamada M, Hirotsune S, Toyoshima YY.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 1954-1965
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019031
[Journal Article] Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.2011
- Author(s)
  Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M.
- Journal Title
  
  J Cell Sci.
  
  Volume: 124 Pages: 857-864
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121518
[Journal Article] Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.2011
- Author(s)
  Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M.
- Journal Title
  
  J Cell Sci.
  
  Volume: 124 Pages: 857-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] mNUDC is required for plus-end directed transport of cytoplasmic dynein and dynactins by kinesin-1.2010
- Author(s)
  Yamada M, Yoshida Y, Mori D, Takitoh T, Nakamura T, H.Iwane A, Yanagida T, Yu-Lee L, Wynshaw-Boris A, Hirotsune S.
- Journal Title
  
  EMBO J 29
  
  Pages: 517-531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-12010
- Author(s)
  Yamada, M., Toba, S., Takitoh, T., Yoshida, Y., Mori, D., Nakamura, T., Iwane, A. H., Yanagida, T., Imai, H., Yu-Lee, L. Y., Schroer, T., Wynshaw-Boris, A., Hirotsune, S.
- Journal Title
  
  EMBO J 29
  
  Pages: 517-531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] mNUDC is required for plus-end directed transport of cytoplasmic dynein and dynactins by kinesin-1.2010
- Author(s)
  Yamada M, Yoshida Y, Mori D, Takitoh T, Nakamura T, H.Iwane A,Yanagida T, Yu-Lee L, Wynshaw-Boris A, Hirotsune S^*.
- Journal Title
  
  EMBO J 29
  
  Pages: 517-531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012046
[Journal Article] Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction2010
- Author(s)
  Pramparo, T., Youn, Y. H., Yingling, J., Hirotsune, S., Wynshaw-Boris, A.
- Journal Title
  
  J Neurosci 30
  
  Pages: 3002-3012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] mNUDC is required for plus-end directed transport of cytoplasmic dynein and dynactins by kinesin-1.2010
- Author(s)
  Yamada M, Yoshida Y, Mori D, Takitoh T, Nakamura T, H.Iwane A, Yanagida T, Yu-Lee L, Wynshaw-Boris A, Hirotsune S^*.
- Journal Title
  
  EMBO J 29
  
  Pages: 517-531
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025028
[Journal Article] mNUDC is required for plus-end directed transport of cytoplasmic dynein and dynactins by kinesin-1.2010
- Author(s)
  Yamada M, Yoshida Y, Mori D, Takitoh T, Nakamura T, H.Iwane A, Yanagida T, Yu-Lee L, Wynshaw-Boris A, Hirotsune S^*.
- Journal Title
  
  EMBOJ 29
  
  Pages: 517-531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058029
[Journal Article] nhibition of calpain increases LIS1 and partially rescues in vivo phenotypes in Lis1 mutant mice : a potential therapy for lissencephaly.2009
- Author(s)
  Yamada M, Yoshida Y, Mori D, Takitoh T, Kengaku M, Satoh M, Sorimachi H, Takao K, Miyakawa T, Wynshaw-Boris A, Hirotsune S^*.
- Journal Title
  
  Nature Medicine 15
  
  Pages: 1202-1207
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025028
[Journal Article] CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity2009
- Author(s)
  Arimura, N., Hattori, A., Kimura, T., Nakamuta, S., Funahashi, Y., Hirotsune, S., Furuta, K., Urano, T., Toyoshima, Y. Y., Kaibuchi, K.
- Journal Title
  
  J Neurochem 111
  
  Pages: 380-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] Distinct dose-dependent cortical neuronal migration and neurite extension defects in Lis1 and Ndel1 mutant mice2009
- Author(s)
  Youn, Y. H., Pramparo, T., Hirotsune, S., Wynshaw-Boris, A.
- Journal Title
  
  J Neurosci 29
  
  Pages: 15520-15530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] nhibition of calpain increases LIS1 and partially rescues in vivo phenotypes in Lis1 mutant mice : a potential therapy for lissencephaly.2009
- Author(s)
  Yamada M, Yoshida Y, Mori D, Takitoh T, Kengaku M, Satoh M, Sorimachi H, Takao K, Miyakawa T, Wynshaw-Boris A, Hirotsune S^*.
- Journal Title
  
  Nature Medicine 15
  
  Pages: 1202-1207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012046
[Journal Article] Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly2009
- Author(s)
  Yamada, M., Yoshida, Y., Mori, D., Takitoh, T., Kengaku, M., Umeshima, H., Takao, K., Miyakawa, T., Sato, M., Sorimachi, H., Wynshaw-Boris, A., Hirotsune, S.
- Journal Title
  
  Nat Med 15
  
  Pages: 1202-1207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] nhibition of calpain increases LIS1 and partially rescues in vivo phenotypes in Lisl mutant mice : a potential therapy for lissencephaly.2009
- Author(s)
  Yamada M, Yoshida Y, Mori D, Takitoh T, Kengaku M, Satoh M, Sorimachi H, Takao K, Miyakawa T, Wynshaw-Boris A, Hirotsune S^*.
- Journal Title
  
  Nature Medicine 15
  
  Pages: 1202-1207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058029
[Journal Article] An Essential Role of the aRKC-Aurora A-NDEL1 Pathway on Neurite Elongation via Modulation of Microtubule Dynamics.2009
- Author(s)
  Daisuke Mori, Masami Yamada, Yuko Mimori-Kiyosue, Yasuhito Shirai, Atsushi Suzuki, Shigeo Ohno, Hideaki Saya, Anthony Wynshaw-Boris, Hirotsune S.
- Journal Title
  
  Nature Cell Biology 11
  
  Pages: 1057-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics2009
- Author(s)
  Mori, D., Yamada, M., Mimori-Kiyosue, Y., Shirai, Y., Suzuki, A., Ohno, S., Saya, H., Wynshaw-Boris, A., Hirotsune, S.
- Journal Title
  
  Nat Cell Biol 11
  
  Pages: 1057-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] nhibition of calpain increases LIS1 and partially rescues in vivo phenotypes in Lis1 mutant mice : a potential therapy for lissencephaly.2009
- Author(s)
  Yamada M, Yoshida Y, Mori D, Rakitoh T, Kengaku M, Satoh M, Sorimachi H, Takao K, Miyakawa T, Wynshaw-Boris A, Hirotsune S.
- Journal Title
  
  Nature Medicine 15
  
  Pages: 1202-1207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] An Essential Role of the aPKC-Aurora A-NDEL1 Pathway on Neurite Elongation via Modulation of Microtubule Dynamics.2009
- Author(s)
  Daisuke Mori, Masami Yamada, Yuko Mimori-Kiyosue, Yasuhito Shirai, Atsushi Suzuki, Shigeo Ohno, Hideaki Saya, Anthony Wynshaw-Boris, Hirotsune S^*.
- Journal Title
  
  Nature Cell Biology 11
  
  Pages: 1057-1068
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025028
[Journal Article] An Essential Role of the aPKC-Aurora A-NDEL1 Pathway on Neurite Elongation via Modulation of Microtubule Dynamics.2009
- Author(s)
  Daisuke Mori, Masami Yamada, Yuko Mimori-Kiyosue, Yasuhito Shirai, Atsushi Suzuki, Shigeo Ohno, Hideaki Saya, Anthony Wynshaw-Boris,_Hirotsune S^*.
- Journal Title
  
  Nature Cell Biology 11
  
  Pages: 1057-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058029
[Journal Article] An Essential Role of the aPKC-Aarora A-NDEL1 Pathway on Neurite Elongation via Modulation of Microtubule Dynamics.2009
- Author(s)
  Daisuke Mori, Masami Yamada, Yuko Mimori-Kiyosue, Yasuhito Shirai, Atsushi Suzuki, Shigeo Ohno, Hideaki Saya, Anthony Wynshaw-Boris, Hirotsune S^*.
- Journal Title
  
  Nature Cell Biology 11
  
  Pages: 1057-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012046
[Journal Article] Protein Phosphatase4 catalytic subunit (PP4c) regulates CDK1 activity and organization of microtubules through dephosphorylation of NDEL1.2008
- Author(s)
  Toyo-oka, K., Mori, D., Yano, Y., Shiota, M., Iwao, H., Goto, H., Inagaki, M., Hiraiwa, N., Muramatsu, M., Yoshiki, A. and Hirotsune, S^*.
- Journal Title
  
  Journal of Cell Biology 180
  
  Pages: 1133-1147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012041
[Journal Article] Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division2008
- Author(s)
  Yingling, J., Youn, Y. H., Darling, D., Toyo-Oka, K., Pramparo, T., Hirotsune, S., Wynshaw-Boris, A.
- Journal Title
  
  Cell 132
  
  Pages: 474-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.2008
- Author(s)
  Yingling J, Youn YH, Darling D, Toyo-Oka K, Pramparo T, Hirotsune S, Wynshaw-Boris A.
- Journal Title
  
  Cell 132
  
  Pages: 474-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012041
[Journal Article] LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein2008
- Author(s)
  Yamada, M., Toba, S., Yoshida, Y., Haratani, K., Mori, D., Yano, Y., Mimori-Kiyosue, Y., Nakamura, T., Itoh, K., Fushiki, S., Setou, M., Wynshaw-Boris, A., Torisawa, T., Toyoshima, Y. Y., Hirotsune, S.
- Journal Title
  
  EMBO J 27
  
  Pages: 2471-2483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390084
[Journal Article] DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1.2007
- Author(s)
  Taya S, Shinoda T, Tsuboi D, Asaki J, Nagai K, Hikita T, Kuroda S, Kuroda K, Shimizu M, Hirotsune S, Iwamatsu A, Kaibuchi K
- Journal Title
  
  J Neurosci. 27
  
  Pages: 15-26
- Data Source
  KAKENHI-PROJECT-17050019
[Journal Article] NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment.2007
- Author(s)
  Mori D, Yano Y, Toyo-oka K, Yoshida N, Yamada M, Muramatsu M, Zhang D, Saya H, Toyoshima YY, Kinoshita K, Wynshaw-Boris A, Hirotsune S.
- Journal Title
  
  Mol Cell Biol. 27
  
  Pages: 352-367
- Data Source
  KAKENHI-PROJECT-18012041
[Journal Article] NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment.2007
- Author(s)
  Mori D, Yano Y, Toyo-oka K, Yoshida N, Yamada M, Muramatsu M, Zhang D, Saya H, Toyoshima YY, Kinoshita K, Wynshaw-Boris A, Hirotsune S
- Journal Title
  
  Mol Cell Biol. 27
  
  Pages: 352-367
- Data Source
  KAKENHI-PROJECT-17050019
[Journal Article] DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1.2007
- Author(s)
  Taya S, Shinoda T, Tsuboi D, Asaki J, Nagai K, Hikita T, Kuroda S, Kuroda K, Shimizu M, Hirotsune S, Iwamatsu A, Kaibuchi K.
- Journal Title
  
  J Neurosci. 27
  
  Pages: 15-26
- Data Source
  KAKENHI-PROJECT-18012041
[Journal Article] Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.2005
- Author(s)
  Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7812-7827
- Data Source
  KAKENHI-PROJECT-16026239
[Journal Article] Recruitment of Katanin P60 by Phosphorylated NDEL1, a LIS1 interacting protein, is Essential for Mitotic Cell Division and Neuronal Migration.2005
- Author(s)
  Kazuhito Toyo-oka, Shinji Sasaki, Yoshihisa Yano, Daisuke Mori, Takuya Kobayashi, Yoko Y.Toyoshima Suzumi, M.Tokuoka, Satoshi Ishii, Takao Shimizu, Masami Muramatsu, Noriko Hiraiwa, Atsushi Yoshiki, Anthony Wynshaw-Boris, Shinji Hirotsune.
- Journal Title
  
  Human Molecular Genetics 14
  
  Pages: 3113-3128
- Data Source
  KAKENHI-PROJECT-16026239
[Journal Article] Recruitment of Katanin P60 by Phosphorylated NDEL1, a LIS1 interacting protein, is Essential for Mitotic Cell Division and Neuronal Migration.2005
- Author(s)
  Kazuhito Toyo-oka, Shinji Sasaki, Yoshihisa Yano, Daisuke Mori, Takuya Kobayashi, Yoko Y.Toyoshima Suzumi M.Tokuoka, Satoshi lshii, Takao Shimizu, Masami Muramatsu, Noriko Hiraiwa, Atsushi Yoshiki, Anthony Wynshaw-Boris, Shinji Hirotsune.
- Journal Title
  
  Human Molecular Genetics 14
  
  Pages: 3113-3128
- Data Source
  KAKENHI-PROJECT-17050019
[Journal Article] Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.2005
- Author(s)
  Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7812-7827
- Data Source
  KAKENHI-PROJECT-17050019
[Journal Article] A new role for expressed pseudogenes as ncRNA : regulation of mRNA stability of its homologous coding gene.2004
- Author(s)
  Yano Y, Saito R, Yoshida N, Yoshiki A, Wynshaw-Boris A, Tomita M, Hirotsune S.
- Journal Title
  
  J Mol Med. 82(7)
  
  Pages: 414-422
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370096
[Journal Article] A new role for expressed pseudogenes as ncRNA : regulation of mRNA stability of its homologous coding gene.2004
- Author(s)
  Yano Y, Saito R, Yoshida N, Yoshiki A, Wynshaw-Boris A, Tomita M, Hirotsune S.
- Journal Title
  
  J Mol Med. 82(7)
  
  Pages: 414-422
- Data Source
  KAKENHI-PROJECT-16012254
[Journal Article] Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective neuronal migration and neuronal circuit formation in a mouse model of lissencephaly.
- Author(s)
  Shiori Toba, Yasuhisa Tamura, Kanako Kumamoto, Masami Yamada, Keizo Takao, Satoko Hattori, Tsuyoshi Miyakawa, Yosky Kataoka, Mitsuyoshi Azuma, Kiyoshi Hayasaka, Masano Amamoto, Keiko Tominaga, Anthony Wynshaw-Boris, Hideki Wanibuchi, Yuichiro Oka, Makoto Sato, Mitsuhiro Kato and Hirotsune, S
- Journal Title
  
  Scientifc reports
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111541
[Presentation] Alpha-synuclein has a unique function in axonal transport2017
- Author(s)
  Mingyue Jin, Shiori Toba, Sakiko Matsumoto, Shinji Hirotsune
- Organizer
  The 12th Biennial Conference of Chinese Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08283
[Presentation] カタニンp80による微小管ネットワーク構築の制御2016
- Author(s)
  金　明月、Oz Pomp、篠田友康、鳥羽栞、鳥澤嵩行、古田健也、大岩和弘、安永卓生、北川大樹、宮田卓樹、Bruno Reversade、広常真治
- Organizer
  生体運動研究合同班会議2016
- Place of Presentation
  キャンパスプラザ京都（京都府、京都市）
- Year and Date
  2016-01-08
- Data Source
  KAKENHI-PROJECT-15K08283
[Presentation] Katanin p80 regulates microtubule organization with NuMA and cytoplasmic dynein during brain development2016
- Author(s)
  Jin M., Pomp O., Toba S., Tan T., Reversade B. and Hirotsune S.
- Organizer
  World life science conference 2016
- Place of Presentation
  国家会議センター(北京市、中国）
- Year and Date
  2016-11-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08283
[Presentation] Katanin p80 regulates microtubule organizations via cytoplasmic dynein during brain development2015
- Author(s)
  Mingyue Jin, Oz Pomp, Bruno Reversade and Shinji Hirotsune
- Organizer
  9th Asian biophysics Association Symposium 2015
- Place of Presentation
  Hangzhou (China)
- Year and Date
  2015-05-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08283

1. Hamada Hiroshi (00208589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KITAGAWA Daiju (80605725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Jin Mingyue (60740404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. MATSUMOTO Sakiko (00789654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. YAMADA Masami (10322851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YASUNAGA Takuo (60251394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. MIYADA Takaki (70311751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. OIWA Kazuhiro (10211096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. FURUTA Ken'ya (40571831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. TOBA Shiori (40419891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 月田早智子 (00188517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 松崎文雄 (10173824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 稲垣昌樹 (30183007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 五島直樹 (70215482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 広野雅文 (10212177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 岸本健雄 (00124222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高橋良輔 (90216771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KIKKAWA Masahide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SUGIMOTO Asako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TOYOSHIMA Fumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MIYAZAWA Atsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NAGAI Kakeharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. REVERSADE Bruno

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. POMP Oz

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
25. ARAI Yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 米村重信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 佐藤真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 片岡洋祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 永井健治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 鰐渕英機

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIROTSUNE Shinji 広常 真治

広常 真治 ヒロツネ シンジ

Research Projects

Research Products

Co-Researchers

新規モデルマウスを用いた機能喪失の観点からのアルツハイマー病の病態生理の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

前駆期パーキンソン病をターゲットとした病態解明と疾患修飾療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Explore of unconventional microtubulesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarify the pathogenic mechnism of microlissencephaly

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経疾患における細胞内輸送の障害:細胞質ダイニンの制御と破綻Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Explore of roles of the centrosome in neurogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cilium-centrosome system regulating biosignal flows

Principal Investigator

Project Period (FY)

Research Category

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増殖と分化のスイッチング:細胞周期制御因子の非分裂細胞における新たな役割の解明Principal Investigator

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細胞質ダイニンのアイドリング複合体の構造解析と活性化メカニズムの解明Principal Investigator

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滑脳症治療への挑戦:カルパインによるリスワン分解機構の解明Principal Investigator

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染色体分配の異常と発がん:細胞分裂におけるダイニン、微小管の制御機構の解明。Principal Investigator

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増殖と分化のスイッチング:神経細胞における細胞周期制御の解明。Principal Investigator

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Elucidation of regulatory mechanisms of cytoplasmic dynein.Principal Investigator

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HIROTSUNE Shinji 広常真治

広常真治ヒロツネシンジ