GON Yasuhiro 権寧博

… Alternative Names

権寧博ゴンヤスヒロ

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Researcher Number	80339316
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 日本大学, 医学部, 教授 2007 – 2017: Nihon University, 医学部, 准教授 2003: 日大, 医学部, 助手 2002: 日本大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 52010:General internal medicine-related / Basic Section 90150:Medical assistive technology-related / Basic Section 52040:Radiological sciences-related / Basic Section 47060:Clinical pharmacy-related / Basic Section 25010:Social systems engineering-related / Basic Section 54030:Infectious disease medicine-related / Respiratory organ internal medicine / Respiratory organ internal medicine
Keywords	Principal Investigator 気管支喘息 / 気道上皮 / 気道上皮細胞 / タイトジャンクション / 好酸球 / 喘息 / バリア機能 / アレルギー / 気道過敏性 / 動物モデル … More / ステロイド抵抗性 / ハウスダスト / IgE / ステロイド / ヒト化マウス / TSLP / IL-33 / microRNA / バイオマーカー / COPD / エクソソーム / マイクロRNA / PCDH1 / 上皮バリア機能 / 透過性バリア / Tight junction / ErbB3 / ErbB1 / Heregulin / 透過性 / 副腎皮質ステロイド / EGFR / 気道炎症 / EGF受容体 / 上皮透過性 / エンドトキシン / マスト細胞 / Toll-like receptor / PKR / 自然免疫 … More Except Principal Investigator COPD / 喘息 / 気管支喘息 / 慢性閉塞性肺疾患 / 吸入治療 / pMDI / バイオマーカー / 免疫ヒト化マウス / 鉄代謝 / ミトコンドリアDNA / タバコ煙 / 心理社会的ストレス / 気道炎症 / ASK1 / MAP kinase / 肺線維症 / 呼吸シミュレータ / 粒子径分布 / 顎顔面像 / 生活習慣病 / 3D画像 / 2D画像 / 顔認識 / 閉塞性睡眠時無呼吸 / DFAT / 脱分化脂肪細胞 / ミトコンドリア損傷 / COVID肺炎 / デジタルX線動画撮影 / 抗凝固療法 / Dual energy CT / 急性肺血栓塞栓症 / ヨード値 / CT / 肺塞栓 / ステロイド抵抗性 / 微差圧センサ / 吸入療法 / マウスピース / 加圧式定量噴霧式吸入器 / 自動噴霧 / 線維化 / 特発性肺線維症 / 臨床呼吸器学 / 免疫関連有害事象 / がん抗原特異的自己抗体 / がん免疫療法 / 血清抗p53抗体 / 肺癌 / ヒトマスト細胞 / 心身相関 / マスト細胞 / ヒト肺マスト細胞 / ヒト脳マスト細胞 / ヒト化マウス / ストレス / オペレーションズリサーチ / 社会システム工学 / 数理工学 / 機械学習 / マルチエージェント / シミュレーション / 感染免疫 / ワクチン / 感染防御 / 非結核性抗酸菌 / 非結核性抗酸菌症 / 細胞性免疫 / 組換えBCG / BCG / 抗酸菌 / ネクロプトーシス / 気腫性変化 / ミトコンドリア / ネクロプト－シス / 気道上皮バリア機能 / ナイメーヘン質問票 / dysfunctional breathing / ストレス耐性 / 神経ペプチド / 気道上皮バリア / oxidative stress / airway epithelial cell / bronchial asthma / TIMP / MMP9 / 喫煙 / アポトーシス / MAPキナーゼ / 肺血管内皮細胞 / 気道リモデリング / 気道平滑筋 / 酸化ストレス / 気道上皮細胞 / マイクロダイセクション / レーザーマイクロダイセクション / プロテオミクス Less

空気力学的粒径測定および呼吸シミュレーターを用いたｐMDI用デバイスの評価・開発
- Principal Investigator
  
  中川一人
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90150:Medical assistive technology-related
- Research Institution
  Nihon University
Elucidation of psychosomatic correlation mechanisms using the brain immune environment of immuno-humanized mice
- Principal Investigator
  
  丸岡秀一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nihon University
Investigation of Mitochondrial Transplantation Therapy Using Dedifferentiated Fat Cells in Refractory Respiratory Diseases
- Principal Investigator
  
  水村賢司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nihon University
気道上皮・骨髄・免疫ヒト化マウスの開発と難治性気道疾患克服に向けた研究基盤の確立Principal Investigator
- Principal Investigator
  
  権寧博
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nihon University
A new method to discover patients with obstructive sleep apnea using artificial intelligence and 2D and 3D images in addition to several complications
- Principal Investigator
  
  陳和夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nihon University
喘息・COPD患者の包括的な治療応答性評価に基づくプレシジョンメディスンの構築
- Principal Investigator
  
  平井啓太
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shinshu University
Acute pulmonary thromboembolism with dual-energy CT and dynamic chest X-ray
- Principal Investigator
  
  岡田真広
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Nihon University
深層学習によるCOVID-19感染伝播と経済活動を同時制御する社会運営戦略の発見
- Principal Investigator
  
  豊谷純
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 25010:Social systems engineering-related
- Research Institution
  Nihon University
Molecular pathogenesis of psychosocial stress-related asthma using immune humanized mice
- Principal Investigator
  
  MARUOKA Shuichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nihon University
Identification of cancer antigen-specific autoantibodies in lung cancer
- Principal Investigator
  
  SHIMIZU Tetsuo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nihon University
Elucidation of the Mechanism of Mitochondrial DNA Release Mediated by Iron Metabolism in Idiopathic Pulmonary Fibrosis
- Principal Investigator
  
  MIZUMURA Kenji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nihon University
微差圧センサを備えたpMDIによる吸入速度の測定および吸入指導・自動噴射への応用
- Principal Investigator
  
  中川一人
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90150:Medical assistive technology-related
- Research Institution
  Nihon University
Establishment and analysis of humanized murine model for refractory asthmaPrincipal Investigator
- Principal Investigator
  
  GON Yasuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nihon University
Study on cellular immunity against Mycobacterium and development of new vaccine
- Principal Investigator
  
  AIZAWA Shihoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nihon University
Analysis of molecular pathogenesis of psychosocial stress-induced asthma
- Principal Investigator
  
  MARUOKA Shuichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nihon University
The role of necroptosis-regulated mitochondrial DNA release in the pathogeneisis of COPD
- Principal Investigator
  
  MIZUMURA Kenji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nihon University
Identification of biomarker for pathogenesis on asthma and COPD based on airway secreted exosomePrincipal Investigator
- Principal Investigator
  
  GON yasuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nihon University
Identification of regulatory factors on airway epithelial barrier integrity and its clinical application for bronchial asthmaPrincipal Investigator
- Principal Investigator
  
  GON Yasuhiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nihon University
Indentification of regulatory factors for airway epithelial barrier and study for the role on airway inflammtionPrincipal Investigator
- Principal Investigator
  
  GON Yasuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nihon University
A proteomic analysis of sample embedded in paraffin from patients with interstitial lung diseases
- Principal Investigator
  
  HAYASHI Shinichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nihon University
Modulation of S1PRs for the treatment of acute respiratory distress syndromePrincipal Investigator
- Principal Investigator
  
  GON Yasuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nihon University
自然免疫機構によるマスト細胞の活性化と感染型気管支喘息の病態への関与Principal Investigator
- Principal Investigator
  
  権寧博
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nihon University
Analysis of signaling molecules in the pathogenesis of COPD and bronchial asthma
- Principal Investigator
  
  HASHIMOTO Shu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nihon University

[Book] 気管支喘息の病態におけるTLRの関与2011
- Author(s)
  権寧博
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21590975
[Book] epithelial growth factors2011
- Author(s)
  権寧博
- Publisher
  Blackwell Publishing Ltd
- Data Source
  KAKENHI-PROJECT-21590975
[Book] 21 epithelial growth factors. Inflammation and Allergy Drug Design2011
- Author(s)
  Gon Y, Hashimoto S
- Publisher
  Blackwell Publishing
- Data Source
  KAKENHI-PROJECT-21590975
[Book] 気管支喘息の病態におけるTLRの関与Annual review of呼吸器2011
- Author(s)
  権寧博, 橋本修
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] A validity study of the Japanese version of the Nijmegen Questionnaire for verifying dysfunctional breathing in Japanese asthmatics2024
- Author(s)
  Kotera Shoko、Maruoka Shuichiro、Kurosawa Yusuke、Arai Hiroyuki、Yamada Shiho、Fukuda Asami、Kozu Yutaka、Hiranuma Hisato、Ito Reiko、Shaku Fumio、Gon Yasuhiro
- Journal Title
  
  Journal of Allergy and Clinical Immunology: Global
  
  Volume: - Issue: 3 Pages: 100247-100247
- DOI
  10.1016/j.jacig.2024.100247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07400
[Journal Article] Fusobacterium nucleatum putatively affects the alveoli by disrupting the alveolar epithelial cell tight junction, enlarging the alveolar space, and increasing paracellular permeability2023
- Author(s)
  Karahashi Yukihiro、Cueno Marni E.、Kamio Noriaki、Takahashi Yuwa、Takeshita Ikuko、Soda Kaori、Maruoka Shuichiro、Gon Yasuhiro、Sato Shuichi、Imai Kenichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 682 Pages: 216-222
- DOI
  10.1016/j.bbrc.2023.10.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07400, KAKENHI-PROJECT-21K10265, KAKENHI-PROJECT-22K21002
[Journal Article] SIRVVD model-based verification of the effect of first and second doses of COVID-19/SARS-CoV-2 vaccination in Japan2022
- Author(s)
  Yuto Omae, Yohei Kakimoto, Makoto Sasaki, Jun Toyotani, Kazuyuki Hara, Yasuhiro Gon, Hirotaka Takahashi
- Journal Title
  
  Mathematical Biosciences and Engineering
  
  Volume: 19 Issue: 1 Pages: 1026-1040
- DOI
  10.3934/mbe.2022047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04535
[Journal Article] Iron-Dependent Mitochondrial Dysfunction Contributes to the Pathogenesis of Pulmonary Fibrosis2022
- Author(s)
  Takahashi Mai、Mizumura Kenji、Gon Yasuhiro、Shimizu Tetsuo、Kozu Yutaka、Shikano Sotaro、Iida Yuko、Hikichi Mari、Okamoto Shinichi、Tsuya Kota、Fukuda Asami、Yamada Shiho、Soda Kaori、Hashimoto Shu、Maruoka Shuichiro
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 643980-643980
- DOI
  10.3389/fphar.2021.643980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08214
[Journal Article] Impact of Removal Strategies of Stay-at-Home Orders on the Number of COVID-19 Infectors and People Leaving Their Homes2021
- Author(s)
  Yuto Omae, Yohei Kakimoto, Jun Toyotani, Kazuyuki Hara, Yasuhiro Gon, Hirotaka Takahashi
- Journal Title
  
  International Journal of Innovative Computing, Information and Control
  
  Volume: 17 Issue: 03 Pages: 1055
- DOI
  10.24507/ijicic.17.03.1055
- ISSN
  1349-4198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04535
[Journal Article] Effectiveness of the COVID-19 Contact-Confirming Application (COCOA) Based on Multi-Agent Simulation2021
- Author(s)
  Yuto Omae, Jun Toyotani, Kazuyuki Hara, Yasuhiro Gon, Hirotaka Takahashi
- Journal Title
  
  Journal of Advanced Computational Intelligence and Intelligent Informatics
  
  Volume: 25 Issue: 6 Pages: 931-943
- DOI
  10.20965/jaciii.2021.p0931
- NAID
  130008119386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04535
[Journal Article] Enzymatic activity of ACE2 regulates type 2 airway inflammation in mice2021
- Author(s)
  Fukuda Asami、Toyoshima Shota、Yamada Shiho、Kurosawa Yusuke、Okayama Yoshimichi、Maruoka Shuichiro、Gon Yasuhiro
- Journal Title
  
  Allergy
  
  Volume: - Issue: 6 Pages: 1913-1917
- DOI
  10.1111/all.14754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K08613, KAKENHI-PROJECT-21K07400
[Journal Article] Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap2021
- Author(s)
  Shirai Toshihiro、Hirai Keita、Gon Yasuhiro、Maruoka Shuichiro、Mizumura Kenji、Hikichi Mari、Itoh Kunihiko、Hashimoto Shu
- Journal Title
  
  Allergol. Int.
  
  Volume: 70 Issue: 1 Pages: 136-139
- DOI
  10.1016/j.alit.2020.05.007
- NAID
  130007966798
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07482
[Journal Article] Reliability of Multi-Agent Based Infection Simulator with Parameters of Isolation Wards2021
- Author(s)
  Yuto Omae, Yohei Kakimoto, Jun Toyotani, Kazuyuki Hara, Yasuhiro Gon, Hirotaka Takahashi
- Journal Title
  
  ICIC Express Letters, Part B: Applications
  
  Volume: 12 Issue: 06 Pages: 577
- DOI
  10.24507/icicelb.12.06.577
- NAID
  40022610874
- ISSN
  2185-2766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04535
[Journal Article] SIR model-based verification of effect of COVID-19 Contact-Confirming Application (COCOA) on reducing infectors in Japan2021
- Author(s)
  Yuto Omae, Yohei Kakimoto, Jun Toyotani, Kazuyuki Hara, Yasuhiro Gon, Hirotaka Takahashi
- Journal Title
  
  Mathematical Biosciences and Engineering
  
  Volume: 18 Pages: 6506-6526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04535
[Journal Article] DsRNA induction of microRNA-155 disrupt tight junction barrier by modulating claudins2020
- Author(s)
  Hiranuma Hisato、Gon Yasuhiro、Maruoka Shuichiro、Kozu Yutaka、Yamada Shiho、Fukuda Asami、Kurosawa Yusuke、Tetsuo Shimizu、Nakagawa Yoshiko、Mizumura Kenji
- Journal Title
  
  Asia Pacific Allergy
  
  Volume: 10 Issue: 2 Pages: e20-e20
- DOI
  10.5415/apallergy.2020.10.e20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07482
[Journal Article] Circulating microRNA‐15b‐5p as a biomarker for asthma‐COPD overlap2020
- Author(s)
  Hirai Keita、Shirai Toshihiro、Shimoshikiryo Takayuki、Ueda Megumi、Gon Yasuhiro、Maruoka Shuichiro、Itoh Kunihiko
- Journal Title
  
  Allergy
  
  Volume: 76 Issue: 3 Pages: 766-774
- DOI
  10.1111/all.14520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K16450
[Journal Article] Forced oscillation technique may identify severe asthma2019
- Author(s)
  Shirai Toshihiro、Hirai Keita、Gon Yasuhiro、Maruoka Shuichiro、Mizumura Kenji、Hikichi Mari、Itoh Kunihiko、Hashimoto Shu
- Journal Title
  
  The Journal of Allergy and Clinical Immunology: In Practice
  
  Volume: 7 Issue: 8 Pages: 2857-2860.e1
- DOI
  10.1016/j.jaip.2019.05.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K16450
[Journal Article] Recent Advances in Allergy Research Using Humanized Mice2019
- Author(s)
  Ito Ryoji、Maruoka Shuichiro、Gon Yasuhiro、Katano Ikumi、Takahashi Takeshi、Ito Mamoru、Izuhara Kenji、Nunomura Satoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 11 Pages: 2740-2740
- DOI
  10.3390/ijms20112740
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K08613, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-18H02368
[Journal Article] Expression of IL-25, IL-33, and Thymic Stromal Lymphopoietin in Nasal Polyp Gland Duct Epithelium in Patients With Chronic Rhinosinusitis2019
- Author(s)
  Nagata Yoshiyuki、Maruoka Shuichiro、Gon Yasuhiro、Mizumura Kenji、Kishi Hiroyuki、Nomura Yasuyuki、Hikichi Mari、Hashimoto Shu、Oshima Takeshi
- Journal Title
  
  American Journal of Rhinology & Allergy
  
  Volume: 33 Issue: 4 Pages: 378-387
- DOI
  10.1177/1945892419835333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-19K09916
[Journal Article] A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis2018
- Author(s)
  Ito R, Maruoka S, Soda K, Katano I, Kawai K, Yagoto M, Hanazawa A, Takahashi T, Ogura T, Goto M, Takahashi R, Toyoshima S, Okayama Y, Izuhara K, Gon Y, Hashimoto S, Ito M, Nunomura S.
- Journal Title
  
  JCI Insight
  
  Volume: 3 Issue: 21
- DOI
  10.1172/jci.insight.121580
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07482, KAKENHI-PROJECT-16H05343, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-16K07103
[Journal Article] Selective release of miRNAs via extracellular vesicles is associated with house dust mite allergen-induced airway inflammation.2017
- Author(s)
  Gon Y, Maruoka S, Inoue T, Kuroda K, Yamagishi K, Kozu Y, Shikano S, Soda K, Lotvall J, Hashimoto S
- Journal Title
  
  Clinical & Experimental Allergy
  
  Volume: 47 Issue: 12 Pages: 1586-1598
- DOI
  10.1111/cea.13016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09196, KAKENHI-PROJECT-16K16151
[Journal Article] NDRG1 is important to maintain the integrity of airway epithelial barrier through claudin-9 expression.2017
- Author(s)
  Gon Y, Maruoka S, Kishi H, Kozu Y, Kazumichi K, Nomura Y, Takeshita I, Oshima T, Hashimoto S
- Journal Title
  
  Cell Biol Int.
  
  Volume: Feb 13 Issue: 7 Pages: 716-725
- DOI
  10.1002/cbin.10741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09196
[Journal Article] DsRNA disrupts airway epithelial barrier integrity through down-regulation of claudin members.2016
- Author(s)
  Gon Y, Maruoka S, Kishi H, Kozu Y, Kuroda K, Mizumura K, Nomura Y, Oshima T, Hashimoto S
- Journal Title
  
  Allergol Int.
  
  Volume: Sep;65 Pages: S56-S58
- DOI
  10.1016/j.alit.2016.04.006
- NAID
  130005418908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09196
[Journal Article] Gene expression analysis in airway-secreting extracellular vesicles upon house dust mite exposure.2016
- Author(s)
  Gon Y, Maruoka S, Inoue T, Mizumura K, Kuroda K, Fukano Y, Yamagishi K, Tsuboi E, Hashimoto S
- Journal Title
  
  Allergol Int.
  
  Volume: Sep;65 Pages: S53-S55
- DOI
  10.1016/j.alit.2016.04.003
- NAID
  130005418886
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09196, KAKENHI-PROJECT-16K16151
[Journal Article] Myeloid differentiation-2 is a potential biomarker for the amplification process of allergic airway sensitization in mice2015
- Author(s)
  Koyama D, Maruoka S, Gon Y, Shintani Y, Sekiyama T, Hiranuma H, Shikano S, Kuroda K, Takeshita I, Tsuboi E, Soda K, Hashimoto S
- Journal Title
  
  Allergol. Int.
  
  Volume: 64 Issue: Supplement.1 Pages: 37-45
- DOI
  10.1016/j.alit.2015.05.011
- NAID
  130005290408
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09196, KAKENHI-PROJECT-25461200
[Journal Article] Protocadherin-1 is a glucocorticoid-responsive critical regulator of airway epithelial barrier function.2015
- Author(s)
  Kozu Y, Gon Y, Maruoka S, Kazumichi K, Sekiyama A, Kishi H, Nomura Y, Ikeda M, Hashimoto S
- Journal Title
  
  BMC Pulmonary Medicine
  
  Volume: 15 Issue: 1 Pages: 80-80
- DOI
  10.1186/s12890-015-0078-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09196
[Journal Article] 細胞外顆粒内RNA情報の臨床応用2015
- Author(s)
  権　寧博、丸岡秀一郎、黒田和道、山岸賢司、橋本　修
- Journal Title
  
  呼吸と循環
  
  Volume: 63 Pages: 541-546
- Data Source
  KAKENHI-PROJECT-15K09196
[Journal Article] 気道分泌型エクソソーム2015
- Author(s)
  権　寧博、丸岡秀一郎、黒田和道、深野義人、山岸賢司、橋本　修
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 64 Pages: 495-500
- NAID
  40020656761
- Data Source
  KAKENHI-PROJECT-15K09196
[Journal Article] Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates airway epithelial barrier integrity2015
- Author(s)
  Shintani Y, Maruoka S, Gon Y, Koyama D, Yoshida A, Kozu Y, Kuroda K, Takeshita I, Tsuboi E, Soda K, Hashimoto S
- Journal Title
  
  Allergol. Int.
  
  Volume: 64 Issue: Supplement.1 Pages: 54-63
- DOI
  10.1016/j.alit.2015.06.004
- NAID
  130005290278
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09196, KAKENHI-PROJECT-25461200
[Journal Article] 気道上皮透過性制御因子の同定2013
- Author(s)
  権　寧博
- Journal Title
  
  日本大学医学部総合医学研究所紀要
  
  Volume: 1 Pages: 71-72
- Data Source
  KAKENHI-PROJECT-24591141
[Journal Article] 【気管支喘息の病態機序解明の新展開】気道上皮細胞と喘息病態2013
- Author(s)
  権　寧博、橋本　修
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 59 Pages: 71-75
- Data Source
  KAKENHI-PROJECT-24591141
[Journal Article] Glucocorticoids enhance airway epithelial barrier integrity2012
- Author(s)
  Sekiyama A, Gon Y, Terakado M, Takeshita I, Kozu Y, Maruoka S, Matsumoto K, Hashimoto S
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 12(2) Pages: 350-7
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] 気管支喘息病態気道上皮2011
- Author(s)
  権寧博
- Journal Title
  
  救急医学
  
  Volume: 35 Pages: 529-532
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] アレルギー性気道炎症における気道上皮機能の変調2011
- Author(s)
  権寧博、羅智靖
- Journal Title
  
  アレルギー・免疫
  
  Volume: 18 Pages: 734-738
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] Glucocorticoids enhance airway epithelial barrier integrity2011
- Author(s)
  権寧博
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 12 Pages: 350-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] Heregulin activation of ErbB2/ErbB3 signaling potentiates the integrity of airway epithelial barrier2011
- Author(s)
  Gon Y, Matsumoto K, Terakado M, Sekiyama A, Maruoka S, Takeshita I, Kozu Y, Okayama Y, Ra C, Hashimoto S
- Journal Title
  
  Exp Cell Res
  
  Volume: 317(13) Pages: 1947-53
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] The Rac1/JNK pathway is critical for EGFR-dependent barrier formation in human airway epithelial cells2011
- Author(s)
  Terakado M, Gon Y, Sekiyama A, Takeshita I, Kozu Y, Matsumoto K, Takahashi N, Hashimoto S
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol
  
  Volume: 300(1)
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.2010
- Author(s)
  権寧博
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 10 Pages: 1062-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] Abrogation of high-affinity IgE receptor-mediated mast cell activation at the effector phase prevents contact hypersensitivity to oxazolone2010
- Author(s)
  権寧博, 羅智靖
- Journal Title
  
  J Invest Dermatol. 130(3)
  
  Pages: 725-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] The Rac1/JNK pathway is critical for EGFR-dependent barrier formation in human airway epithelial cells.2010
- Author(s)
  権寧博
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 300 Pages: 56-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates lipopolysaccharide-induced tissue factor expression in pulmonary microvasculature.2010
- Author(s)
  権寧博
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 10 Pages: 1062-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] Mast cell death induced by 24(S), 25-epoxycholesterol.2010
- Author(s)
  権寧博
- Journal Title
  
  Exp Cell Res.
  
  Volume: 316 Pages: 3272-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack2009
- Author(s)
  権寧博, 羅智靖
- Journal Title
  
  J Allergy Clin Immunol. 124(5)
  
  Pages: 913-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] PI3Kgamma differentially regulates FcepsilonRI-mediated degranulation and migration of mast cells by and toward antigen2009
- Author(s)
  権寧博, 羅智靖
- Journal Title
  
  Int Arch Allergy Immunol. 1
  
  Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590975
[Journal Article] PI3Ky Differentially Regulates Fc E RI-Mediated Degranulation and Migration of Mast Cells by and toward Antigen2009
- Author(s)
  Endo D, Gon Y, Nunomura S, Kyoko N, Hashimoto S, Ra C
- Journal Title
  
  Int. Arch. Allergy Immunol 149 Supple 1 (in press)
- Data Source
  KAKENHI-PROJECT-19590918
[Journal Article] Toll-like receptors and airway inflammation.2008
- Author(s)
  Gon Y.
- Journal Title
  
  Allergol Int. 57
  
  Pages: 33-7
- NAID
  10021245819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590918
[Journal Article] Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells.2008
- Author(s)
  GON Y
- Journal Title
  
  Int Immunopharmacol. Jun ; 8(6)
  
  Pages: 874-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590918
[Journal Article] Analysis of gene expression in human bronchial epithelial cells upon influenza virus infection and regulation by p38 mitogen-activated protein kinase and c-Jun-N-terminal kinase2008
- Author(s)
  Hayashi S, Jibiki I, Asai Y, Gon Y, Kobayashi T, Ichiwata T, Shimizu K, Hashimoto S
- Journal Title
  
  Respirology Mar;13(2)
  
  Pages: 203-14
- Data Source
  KAKENHI-PROJECT-19590918
[Journal Article] Inhibitory effects of parthenolide on antigen-induced microtubule formation and degranulation in mast cells2008
- Author(s)
  Miyata N, Gon Y, Nunomura S, Endo D, Yamashita K, Matsumoto K, Hashimoto S, Ra C
- Journal Title
  
  Int Immunopharmacol Jun;8(6)
  
  Pages: 874-80
- Data Source
  KAKENHI-PROJECT-19590918
[Journal Article] An inhibitory effect of A20 on NF-kappaB activation in airway epithelium upon influenza virus infection2006
- Author(s)
  Onose A, Hashimoto S, Hayashi S, Maruoka S, Kumasawa F, Mizumura K, Jibiki I,Matsumoto K, Gon Y, Kobayashi T, Takahashi N, Shibata Y, Abiko Y, Shibata T, Shimizu K, Horie T
- Journal Title
  
  Eur J Pharmacol Jul 17;541(3) Epub 2006 May 20
  
  Pages: 198-204
- Data Source
  KAKENHI-PROJECT-19590918
[Journal Article] Apoptosis signal- regulating kinase 1 in leukotriene D4-induced activator protein-1 in airway smooth muscle cells2005
- Author(s)
  Kumasawa F, Hashimoto S, Onose A, Jibiki I , Mizumura K, Matsumoto M, MaruokaS, Gon Y, Kobayashi T, Takahashi N, Ichijo H, Horie
- Journal Title
  
  Eur J Pahrmacol Jul 4;517(1-2)
  
  Pages: 11-6
- Data Source
  KAKENHI-PROJECT-19590918
[Journal Article] Role of mitogen-activated protein kinases in influenza virus induction of prostaglandin E2 from arachidonic acid in bronchial epithelial cells.2003
- Author(s)
  Mizumura K, Hashimoto S, Maruoka S, Gon Y, Kitamura N, Matsumoto K, Hayashi S, Shimizu K, Horie T
- Journal Title
  
  Clin Exp Allergy. 33(9)
  
  Pages: 1244-1251
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570568
[Journal Article] Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells.2003
- Author(s)
  Machine T, Hashimoto S, Maruoka S, Gon Y, Shinichi H, Nishitoh H, Ichijo H, Horie T
- Journal Title
  
  Crit Care Med. 31(12)
  
  Pages: 2776-2781
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570568
[Journal Article] ASK1 regulates influenza virus infection-induced apoptotic cell death.2003
- Author(s)
  Maruoka S, Hashimoto S, Gon Y, Nishitoh H, Takeshita I, Asai Y, Mizumura K, Shimizu K, Ichijo H, Horie T
- Journal Title
  
  Biochem Biophys Res Commun. 307(4)
  
  Pages: 870-876
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570568
[Patent] 上皮バリア機能の増強方法及び増強剤2012
- Inventor(s)
  権　寧博
- Industrial Property Rights Holder
  権　寧博
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2014-012650
- Filing Date
  2012-07-05
- Acquisition Date
  2014-01-23
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] Angiotensin-converting enzyme 2 (ACE2) activator attenuates house dust mite-induced allergic inflammation in mice2021
- Author(s)
  Fukuda A, Maruoka S, Yamada S, Kurosawa Y, Kozu Y, Gon Y
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology
- Data Source
  KAKENHI-PROJECT-19K08613
[Presentation] Induction of asthma by sensitization to substances derived from periodontal disease bacteria2021
- Author(s)
  Kurosawa Y, Toyoshima S，Soda K，Takeshita I，Maruoka S， Gon Y
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07400
[Presentation] Iron-dependent mitochondrial dysfunction contributes to the pathogenesis of pulmonary fibrosis2021
- Author(s)
  Kenji Mizumura, Mai Takahashi, Shuichiro Maruoka, Tetsuo Shimizu, Yutaka Kozu, Sotaro Shikano, Yuko Iida, Mari Hikichi, Shinichi Okamoto, Kota Tsuya, Asami Fukuda, Shiho Yamada, Kaori Soda, Shu Hashimoto, and Yasuhiro Gon
- Organizer
  THE 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08214
[Presentation] Mitochondria in COPD2021
- Author(s)
  Kenji Mizumura，Augustine. M.K. Choi，Shu Hashimoto，Yasuhiro Gon
- Organizer
  THE 25th Congress of the Asian Pacific Society of Respirology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08214
[Presentation] The mechanism of cigarette smoke-induced mitochondrial DNA release in pulmonary epithelial cell2021
- Author(s)
  Kenji Mizumura, Mai Takahashi, Mari Hikichi, Shiho Yamada, Asami Fukuda, Yusuke Kurosawa, Kaori Soda, Shuichiro Maruoka and Yasuhiro Gon
- Organizer
  THE 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08214
[Presentation] エクソソームの呼吸器疾患バイオマーカーへの応用2017
- Author(s)
  権　寧博、山岸賢司、井上寿男、黒田和道、坪井絵莉子、木澤靖夫、橋本　修
- Organizer
  平成28年度　日本大学学部連携研究推進シンポジウム
- Place of Presentation
  日本大学会館2階大講堂 (東京都、千代田区)
- Year and Date
  2017-02-18
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] 喘息・COPDの病態とバイオマーカー2016
- Author(s)
  権　寧博
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2016-04-10
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] 急性肺障害モデルにおけるexosome由来miRNAの発現解析2016
- Author(s)
  鹿野壮太郎、井上寿男、権　寧博、丸岡秀一郎、黒田和道、山岸賢司、曽田香織、橋本　修
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] マウスLPS誘導性肺障害におけるエクソソームのRNA発現解析2016
- Author(s)
  井上寿男、権　寧博、丸岡秀一郎、鹿野壮太郎、黒田和道、山岸賢司、曽田香織、橋本　修
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] エクソソームの疾患バイオマーカーとしての可能性2015
- Author(s)
  権　寧博、丸岡秀一郎、橋本　修
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都、千代田区)
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] マウス喘息モデルを用いた気道分泌型exosomeの解析2015
- Author(s)
  権　寧博、丸岡秀一郎、黒田和道、山岸賢司、鹿野壮太郎、曽田香織、坪井絵莉子、竹下郁子、橋本　修
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪国際館パミール(東京都、港区)
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] Epithelial biology in the pathogenesis of airway inflammation2015
- Author(s)
  Yasuhiro gon
- Organizer
  20th Congress of the Asia pacific Society of Respirology
- Place of Presentation
  Kuala lumpur(Malaysia)
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] アレルギー性気道炎症における気道分泌型exosomeの役割2015
- Author(s)
  権　寧博、丸岡秀一郎、井上寿男、曽田香織、神津　悠、鹿野壮太郎、橋本　修
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都、千代田区)
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] ウイルス感染による気道上皮バリア障害におけるmir-155の役割2015
- Author(s)
  神津　悠、岸　博介、権　寧博、竹下郁子、野村泰之、水村賢司、丸岡秀一郎、大島猛史、橋本　修
- Organizer
  アレルギー、好酸球研究会2015
- Place of Presentation
  学術総合センター(東京都、千代田区)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] マウスLPS誘導性肺障害におけるBALF中エクソソームのRNA発現解析2015
- Author(s)
  井上寿男、権　寧博、丸岡秀一郎、鹿野壮太郎、黒田和道、山岸賢司、曽田香織、橋本　修
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都、千代田区)
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] マウス喘息モデルにおける気道分泌型細胞外小胞RNAの網羅的発現解析2015
- Author(s)
  権　寧博、井上寿男、深野義人、山岸賢司、黒田和道、鹿野壮太郎、曽田香織、水村賢司、丸岡秀一郎、橋本　修
- Organizer
  アレルギー、好酸球研究会2015
- Place of Presentation
  学術総合センター(東京都、千代田区)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K09196
[Presentation] 喘息病態におけるエクソソームを介した新たな遺伝子発現制御機構2013
- Author(s)
  権　寧博、丸岡秀一郎、平沼久人、関山忠孝、小山大輔、新谷榮崇、曽田香織、竹下郁子、井上寿男、橋本　修
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] Selective Secretion Of Exosomal Micrornas In A Mice Model Of Bronchial Asthma.2013
- Author(s)
  Gon Y, Maruoka S, Shintani Y, Koyama D, Sekiyama T, Hiranuma H, Inoue T, Takeshita I, Soda K, Hashimoto S
- Organizer
  18th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] Steroid-Inducible Genes Regulate Airway Epithelial Barrier Function.2013
- Author(s)
  Shintani Y, Maruoka S, Koyama D, Kozu Y, Hiranuma H, Sekiyama T, Gon Y, Hashimoto S
- Organizer
  18th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] 気道上皮バリア機能におけるステロイド誘導性遺伝子の役割2013
- Author(s)
  新谷榮崇、丸岡秀一郎、権　寧博、関山晶子、神津　悠、小山大輔、曽田香織、竹下郁子、橋本　修
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] PCDH1, An AHR Susceptibility Gene, Promotes Epithelial Barrier Integrity And Is Induced By Glucocorticoids In The Human Airway.2013
- Author(s)
  Gon Y, Kozu Y, Maruoka S, Sekiyama A, Terakado M, Tsuboi E, Takeshita I, Hashimoto S.
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Philadelphia,USA
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] 気道過敏性感受性遺伝子であるPCDH1の気道バリア機能における役割2013
- Author(s)
  神津　悠、権　寧博、関山晶子、寺門正裕、竹下郁子、松本　健、丸岡秀一郎、橋本　修
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] 気道上皮バリア機能におけるステロイド誘導性遺伝子の役割2013
- Author(s)
  新谷榮崇、丸岡秀一郎、小山大輔、平沼久人、関山忠孝、松本　健、権　寧博、橋本　修
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] Airway epithelial cells in pathogenesis of asthma.2012
- Author(s)
  Yasuhiro Gon, Hashimoto S
- Organizer
  The 17 Congress of the APSR. Hong Kong.
- Place of Presentation
  Hong Kong
- Invited
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] 吸入ステロイドによる気道バリア増強作用によるPCDH1の役割2012
- Author(s)
  神津　悠、権　寧博、関山晶子、寺門正裕、竹下郁子、丸岡秀一郎
- Organizer
  第６２回　日本アレルギー学会秋季学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24591141
[Presentation] シンポジウム気管支喘息の病態解明の新展開気道上皮細胞2011
- Author(s)
  権寧博, 橋本修
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] 気道上皮バリア機能の変調と喘息病態2011
- Author(s)
  権寧博
- Organizer
  第15回アレルギー・気道上皮細胞研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] The Rac1/JNK pathway is critical for EGFR-dependent barrier formation in human airway epithelial cells2011
- Author(s)
  Terakado M, Gon Y, Sekiyama A, Takeshita I, Kozu Y, Matsumoto K, Takahashi N and Hashimoto S
- Organizer
  ATS international conference
- Place of Presentation
  Denver. USA
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] Glucocorticoids Enhance Airway Epithelial Barrier Integrity2011
- Author(s)
  Sekiyama A, Gon Y, Terakado M, Takeshita I, Kozu Y, Matsumoto K, and Hashimoto S
- Organizer
  ATS international conference
- Place of Presentation
  Denver. USA
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] 難治性喘息の病態気道構成細胞2011
- Author(s)
  権寧博
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] 気管支喘息の病態解明の新展開気道上皮細胞2011
- Author(s)
  権寧博
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] シンポジウム:気道構成細胞から喘息の発症メカニズムを探る.気道上皮細胞2010
- Author(s)
  権寧博, 橋本修
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] 気道構成細胞から喘息の発症メカニズムを探る気道上皮細胞2010
- Author(s)
  権寧博
- Organizer
  日本アレルギー学会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] シンポジウム気管支喘息の病態の新知見-TLRの関与2010
- Author(s)
  権寧博, 羅智靖, 橋本修
- Organizer
  第50回日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] 気管支喘息の病態の新知見-TLRの関与2010
- Author(s)
  権寧博
- Organizer
  日本呼吸器学会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] 気道上皮のバリア機能制御における各種ErbB受容体の役割2009
- Author(s)
  権寧博
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] Erb受容体シグナルにおける気道上皮透過性バリア機能の役割2009
- Author(s)
  権寧博, 寺門正裕, 関山昌子, 神津悠, 竹下郁子, 松本健, 岡山吉道, 羅智靖, 橋本修
- Organizer
  第59回日本アレルギー学会秋季臨床大会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] Heregulin-activation of Erb2/Erb3 heterodimaers is essensial for the regulation of permeability barrier in airway epithelial cells2009
- Author(s)
  Gon Y, Terakado M, Sekiyama A, Matsumoto K, Kozu Y, Hashimoto S
- Organizer
  14th Congress of the Asian-Pacific Society of Respirology
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21590975
[Presentation] 吸入ステロイドの気道上皮透過性バリア機能に及ぼす影響2008
- Author(s)
  関山晶子、権寧博、寺門正裕、遠藤大介、山下京子、竹下郁子、小林朋子、羅智靖、橋本修
- Organizer
  58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] 吸入ステロイドの気道上皮透過性バリア機能に及ぼす影響2008
- Author(s)
  関山晶子、権寧博、寺門正裕、遠藤大介、山下京子、竹下郁子、小林朋子、羅智靖、橋本修
- Organizer
  第48回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] Role of epithelial dysfunction in asthma and chronic obstructive pulmonary disease2008
- Author(s)
  権寧博
- Organizer
  日本呼吸器学会
- Place of Presentation
  神戸
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] EGF受容体による気道上皮バリア機構の制御についての解析2008
- Author(s)
  寺門正裕、権寧博、関山晶子、遠藤大介、山下京子、高橋典明、橋本修
- Organizer
  48回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] The different roles of PI3K and Sphk in mast cell degranulation and migration2007
- Author(s)
  Endo D, Gon Y, Nunomura S, Yamashita K, Miyata N, Hashimoto S, Ra C
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] The roles of Fyn on β- chain ITAM-independent mast cell activation2007
- Author(s)
  YAMASHITA K, GON Y, ENDO D, NUNOMURA S, MIYATA N, HASHIMOTO S ,RA C
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] スフィンゴシンキナーゼと炎症日本大学文部科学省・私立大学学術研究高度化推進事業ハイテクリサーチセンター整備事業2007
- Author(s)
  権寧博、羅智靖
- Organizer
  公開シンポジウム「ヒトの疾病に対する分子医療の確立」
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] マスト細胞の脱穎粒と細胞遊走におけるPI3KとSphKの役割の違いについて2007
- Author(s)
  遠藤大介、権寧博1、山下京子、布村聡、宮田直子、橋本修、羅智靖
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] 抗原によるマスト細胞遊走におけるlgE受容体β鎖非依存的な情報伝達経路の関与2007
- Author(s)
  遠藤大介、権寧博、山下京子、福永牧子、宮田直子、小野瀬輝、熊澤文雄、松本健、布村聡、橋本修、羅智靖
- Organizer
  第47回日本呼吸器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] 抗原に対するマスト細胞遊走のメカニズム2007
- Author(s)
  遠藤大介、権寧博、山下京子、布村聡、宮田直子、橋本修、羅智靖
- Organizer
  第11回呼吸病態研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] マスト細胞のIL-13産生のスフィンゴシンキナーゼによる制御2007
- Author(s)
  山下京子、権寧博、遠藤大介、福永牧子、宮田直子、小野瀬輝、熊澤文雄、橋本修、羅智靖
- Organizer
  第47回日本呼吸器学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] Regulation of lung barrier function by sphingosine-l-phoshate2006
- Author(s)
  Gon Y,
- Organizer
  9th pneumo colloquium
- Place of Presentation
  東京
- Year and Date
  2006-06-30
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] スフィンゴシン1一リン酸(SIP)とTNFの相互作用は肺傷害を増強する2006
- Author(s)
  権寧博, 橋本修
- Organizer
  第46回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2006-06-01
- Data Source
  KAKENHI-PROJECT-19590918
[Presentation] 肺内スフィンゴシン1一リン酸(SIP)の増加は肺水腫を引き起こす2006
- Author(s)
  権寧博, 橋本修
- Organizer
  第46回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2006-06-01
- Data Source
  KAKENHI-PROJECT-19590918

1. MARUOKA Shuichiro (80599358)

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GON Yasuhiro 権 寧博

権 寧博 ゴン ヤスヒロ

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気道上皮・骨髄・免疫ヒト化マウスの開発と難治性気道疾患克服に向けた研究基盤の確立Principal Investigator

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Establishment and analysis of humanized murine model for refractory asthmaPrincipal Investigator

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GON Yasuhiro 権寧博

権寧博ゴンヤスヒロ