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TAKAHASHI NAOTO  高橋 直人

… Alternative Names

TAKAHASHI Naoto  高橋 直人

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Researcher Number 80344753
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6758-3787
Affiliation (Current) 2025: 秋田大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2024: 秋田大学, 医学系研究科, 教授
2018 – 2021: 秋田大学, 医学系研究科, 教授
2017: 秋田大学, 医学部, 教授
2016: 秋田大学, 医学部血液腎臓膠原病内科, 教授
2014 – 2016: 秋田大学, 医学(系)研究科(研究院), 教授 … More
2015: 秋田大学, 大学院医学系研究科, 教授
2013: 秋田大学, 医学部, 講師
2011 – 2013: 秋田大学, 医学(系)研究科(研究院), 講師 Less
Review Section/Research Field
Principal Investigator
Hematology / Basic Section 54010:Hematology and medical oncology-related
Except Principal Investigator
Medical pharmacy / Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords
Principal Investigator
慢性骨髄性白血病 / 薬剤耐性 / チロシンキナーゼ阻害薬 / 薬物濃度 / BIM / SNP / 薬物輸送蛋白 / T/Nk細胞プロファイリング / 制御性T細胞 / 薬物トランスポーター … More / NK細胞 / T細胞 / レナリドミド / 治療効果 / 血中濃度 / 多発性骨髄腫 / 骨髄性白血病 / microRNA / Bmi-1 / miR-200c / miRNA / CML … More
Except Principal Investigator
TDM / 血中濃度 / 分子標的治療薬 / 分子標的抗がん剤 / 赤血球造血 / CASIN / CASIN(阻害剤) / TRL4 / LPS / 好中球 / 造血幹細胞 / Cdc42 / 脱核 / ヒト赤芽球 / 膠原病 / 薬物動態学的相互作用 / イトラコナゾール / エベロリムス / 骨髄移植 / 腎移植 / 薬物動態 / CYP3A5遺伝子多型 / タクロリムス / 抗がん剤 / 個別化治療 / 精密医療 / side population / リンパ腫 / SAHA / マントル細胞リンパ腫 / SP細胞 / Bmi-1 / 皮膚浸潤性T細胞リンパ腫 / ケモカインレセプターCCR6 / 転移浸潤 / 悪性リンパ腫 / metastasis / CCR6 / miR-150 / miR-16 / Side population / CTCL / malignant lymphoma / miRNA / 個別化療法 / 遺伝子多型 Less
  • Research Projects

    (8 results)
  • Research Products

    (74 results)
  • Co-Researchers

    (15 People)
  •  TKI抵抗性CMLに対するエキソーム解析とFRET解析の統合による個別化治療の可能性Principal Investigator

    • Principal Investigator
      高橋 直人
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Akita University
  •  The mechanism of organelle relocation in human erythroblasts.

    • Principal Investigator
      Ubukawa Kumi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Akita University
  •  Therapeutic drug management of the novel agents for multiple myelomaPrincipal Investigator

    • Principal Investigator
      Takahashi Naoto
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Akita University
  •  Development of a new treatment strategy using TDM for next generation anticancer drug

    • Principal Investigator
      Miura Masatomo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Akita University
  •  Do patients taking tacrolimus need to undergo CYP3A5 genotyping along with blood concentration monitoring?

    • Principal Investigator
      Niioka Takenori
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Akita University
  •  Identification of microRNAs that might be therapeutic target of malignant lymphomas

    • Principal Investigator
      Tagawa Hiroyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Akita University
  •  Therapeutic drug management of tyrosine kinase inhibitor

    • Principal Investigator
      MIURA MASATOMO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Akita University
  •  Detection for miRNA dysregulation in CMLPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoto
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Akita University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book

  • [Book] Therapeutic Drug Monitoring of Imatinib for Chronic Myeloid Leukemia Patients. Myeloid Leukemia–Clinical Diagnosis and Treatment2011

    • Author(s)
      Takahashi, N and Miura, M
    • Publisher
      INTECH, Croatia
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] IL-6 Generated from Human Hematopoietic Stem and Progenitor Cells through TLR4 Signaling Promotes Emergency Granulopoiesis by Regulating Transcription Factor Expression2021

    • Author(s)
      Sasaki Yumi、Guo Yong-Mei、Goto Tatsufumi、Ubukawa Kumi、Asanuma Ken、Kobayashi Isuzu、Sawada Kenichi、Wakui Hideki、Takahashi Naoto
    • Journal Title

      The Journal of Immunology

      Volume: 207 Issue: 4 Pages: 1078-1086

    • DOI

      10.4049/jimmunol.2100168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08315, KAKENHI-PROJECT-20K17367
  • [Journal Article] Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts2020

    • Author(s)
      Ubukawa Kumi、Goto Tatsufumi、Asanuma Ken、Sasaki Yumi、Guo Yong-Mei、Kobayashi Isuzu、Sawada Kenichi、Wakui Hideki、Takahashi Naoto
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 11806-11806

    • DOI

      10.1038/s41598-020-68799-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Journal Article] 1.ATP produced by anaerobic glycolysis is essential for enucleation of human erythroblasts.2019

    • Author(s)
      Goto T, Ubukawa K, Kobayashi I, Sugawara K, Asanuma K, Sasaki Y, Guo YM, Takahashi N, Sawada K, Wakui H, Nunomura W.
    • Journal Title

      Exp Hematol.

      Volume: 72

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Journal Article] Thrombocytopenia Caused by a Tea Beverage of <i>Taxus yunnanensis</i> (Chinese Yew)2019

    • Author(s)
      Ubukawa K, Kameoka Y, Guo YM, Nara M, Watanabe A, Fujishima M, Fujishima N, Yoshioka T, Takahashi N.
    • Journal Title

      Intern. Med.

      Volume: 58 Issue: 21 Pages: 3153-3156

    • DOI

      10.2169/internalmedicine.2967-19

    • NAID

      130007740721

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2019-11-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Journal Article] The localization of α-synuclein in the process of differentiation of human erythroid cells2018

    • Author(s)
      Araki Katsuya、Sugawara Kotomi、Hayakawa Eri H.、Ubukawa Kumi、Kobayashi Isuzu、Wakui Hideki、Takahashi Naoto、Sawada Kenichi、Mochizuki Hideki、Nunomura Wataru
    • Journal Title

      International Journal of Hematology

      Volume: 108 Issue: 2 Pages: 130-138

    • DOI

      10.1007/s12185-018-2457-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08315, KAKENHI-PROJECT-18K11135, KAKENHI-PROJECT-16K09716
  • [Journal Article] Clinical effects of single nucleotide polymorphisms on drug-related genes in Japanese metastatic renal cell carcinoma patients treated with sunitinib.2017

    • Author(s)
      Numakura K, Tsuchiya N, Kagaya H, Takahashi M, Tsuruta H, Inoue T, Narita S, Huang M, Satoh S, Niioka T, Miura M, Habuchi T.
    • Journal Title

      Anticancer Drugs.

      Volume: 28(1) Pages: 97-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Journal Article] Routine therapeutic drug monitoring of tyrosine kinase inhibitors by HPLC-UV or LC-MS/MS methods.2016

    • Author(s)
      Miura M, Takahashi N.
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 31(1) Issue: 1 Pages: 12-20

    • DOI

      10.1016/j.dmpk.2015.09.002

    • NAID

      50014431236

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Journal Article] Therapeutic drug monitoring enables safe and effective lenalidomide therapy in patients with multiple myeloma on hemodialysis2016

    • Author(s)
      Takahiro Kobayashi, Takenori Niioka, Masatomo Miura, Naoto Takahashi
    • Journal Title

      Ann Hematol

      Volume: 95(12) Issue: 12 Pages: 2087-2088

    • DOI

      10.1007/s00277-016-2809-5

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461414
  • [Journal Article] Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma cells.2016

    • Author(s)
      Ikeda S, Kitadate A, Ito M, Abe F, Nara M, Watanebe A, Takahashi N, Miyagaki T, Sugaya M, Tagawa H.
    • Journal Title

      Oncotarget

      Volume: in press Issue: 12 Pages: 13563-13574

    • DOI

      10.18632/oncotarget.6916

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461405, KAKENHI-PROJECT-16K10146
  • [Journal Article] MicroRNA-16 mediates the regulation of a senescence-apoptosis switch in cutaneous T-cell and other non-Hodgkin lymphomas.2016

    • Author(s)
      Kitadate A, Ikeda S, Teshima K, Ito M, Toyota I, Hasunuma N, Takahashi N, Miyagaki T, Sugaya M, Tagawa H.
    • Journal Title

      Oncogene

      Volume: in press Issue: 28 Pages: 3692-3704

    • DOI

      10.1038/onc.2015.435

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461405, KAKENHI-PROJECT-16K10146
  • [Journal Article] Therapeutic drug monitoring enables safe and effective lenalidomide therapy in patients with multiple myeloma on hemodialysis.2016

    • Author(s)
      Kobayashi T, Niioka T, Miura M, Takahashi N.
    • Journal Title

      Ann Hematol.

      Volume: 95(12) Pages: 2087-2088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Journal Article] Analysis of clinical characteristics and prognostic factors for angioimmunoblastic T-cell lymphoma.2015

    • Author(s)
      Kameoka Y, Takahashi N, Itou S, Kume M, Noji H, Kato Y, Ichikawa Y, Sasaki O, Motegi M, Ishiguro A, Tagawa H, Ishizawa K, Ishida Y, Ichinohasama R, Harigae H, Sawada K.
    • Journal Title

      Int J Hematol

      Volume: 101 Issue: 6 Pages: 536-542

    • DOI

      10.1007/s12185-015-1763-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-25461405, KAKENHI-PROJECT-25461431
  • [Journal Article] Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease.2015

    • Author(s)
      Togashi M, Niioka T, Komatsuda A, Nara M, Okuyama S, Omokawa A, Abumiya M, Wakui H, Takahashi N, Miura M.
    • Journal Title

      Eur J Clin Pharmacol.

      Volume: 71 Issue: 9 Pages: 1091-7

    • DOI

      10.1007/s00228-015-1901-4

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Effects of CYP3A5 polymorphism and the tacrolimus 12?h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis.2015

    • Author(s)
      Niioka T, Komatsuda A, Kato S, Togashi M, Okuyama S, Omokawa A, Nara M, Wakui H, Takahashi N, Miura M.
    • Journal Title

      Xenobiotica.

      Volume: 45 Pages: 1147-53

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Treatment of multiple myeloma in Akita: features and outcomes in the era of novel agents.2014

    • Author(s)
      Shida S, Takahashi N, Niioka T, Kitabayashi A, Kawabata Y, Kume M, Saitoh H, Hatano Y, Ichikawa Y, Kuroki J, Motegi M, Kobayashi T, Kameoka Y, Tagawa H, Fujishima N, Yoshioka T, Hirokawa M, Miura M, Sawada K.
    • Journal Title

      J Clin Exp Hematop

      Volume: 54 Pages: 89-93

    • NAID

      130004886480

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Journal Article] A limited sampling model to estimate exposure to lenalidomide in multiple myeloma patients.2014

    • Author(s)
      Shida S, Takahashi N, Miura M, Niioka T, Matsumoto M, Hagihara M, Kobayashi T, Abumiya M, Kameoka Y, Fujishima N, Tagawa H, Hirokawa M, Sawada K.
    • Journal Title

      Ther Drug Monit

      Volume: 36 Issue: 4 Pages: 505-9

    • DOI

      10.1097/ftd.0000000000000034

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Journal Article] A Limited Sampling Model to Estimate Exposure to Lenalidomide in Multiple Myeloma Patients.2014

    • Author(s)
      Shida S, Takahashi N, Miura M, Niioka T, Matsumoto M, Hagihara M, Kobayashi T, Abumiya M, Kameoka Y, Fujishima N, Tagawa H, Hirokawa M, Sawada K.
    • Journal Title

      Ther Drug Monit.

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Multicenter phase II clinical trial of nilotinib for patients with imatinib-resistant or -intolerant chronic myeloid leukemia from the East Japan CML study group evaluation of molecular response and the efficacy and safety of nilotinib.2014

    • Author(s)
      Takahashi N, Miura M, Kuroki J, Mitani K, Kitabayashi A, Sasaki O, Kimura H, Imai K, Tsukamoto N, Noji H, Kondo T, Motegi M, Kato Y, Mita M, Saito H, Yoshida C, Torimoto Y, Kimura T, Wano Y, Nomura J, Yamamoto S, Mayama K, Honma R, Sugawara T, Sato S, Shinagawa A, Abumiya M, Niioka T, Harigae H, Sawada K.
    • Journal Title

      Biomark Res.

      Volume: 20;2(1) Issue: 1 Pages: 2-6

    • DOI

      10.1186/2050-7771-2-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590168, KAKENHI-PROJECT-25461431
  • [Journal Article] Therapeutic drug management of BCR-ABL tyrosine kinase inhibitor for chronic myeloid leukemia patients.2014

    • Author(s)
      Miura M, Takahashi N.
    • Journal Title

      Rinsho Ketsueki

      Volume: 54 Pages: 1720-1729

    • NAID

      10031196316

    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells2013

    • Author(s)
      Nara M, Teshima K, Watanabe A, Ito M, Iwamoto K, Kitabayashi A, Kume M, Hatano Y, Takahashi N, Iida S, Sawada K, Tagawa H
    • Journal Title

      PLoS One

      Volume: 8(3)

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] A multicenter clinical study evaluating the confirmed complete molecular response rate in imatinib-treated patients with chronic phase chronic myeloid leukemia by using the international scale of real-time quantitative polymerase chain reaction.2013

    • Author(s)
      Shinohara Y, Takahashi N, Nishiwaki K, Hino M, Kashimura M, Wakita H, Hatano Y, Hirasawa A, Nakagawa Y, Itoh K, Masuoka H, Aotsuka N, Matsuura Y, Takahara S, Sano K, Kuroki J, Hata T, Nakamae H, Mugitani A, Nakane T, Miyazaki Y, Niioka T, Miura M, Sawada K.
    • Journal Title

      Haematologica.

      Volume: 98(9) Issue: 9 Pages: 1407-13

    • DOI

      10.3324/haematol.2013.085167

    • NAID

      120006986100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells2013

    • Author(s)
      Nara M, Teshima K, Watanabe A, Ito M, Iwamoto K, Kitabayashi A, Kume M, Hatano Y, Takahashi N, Iida S, Sawada K, Tagawa H
    • Journal Title

      PLos One

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Journal Article] Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells2013

    • Author(s)
      Nara M, Teshima K, Watanabe A, Ito M, Iwamoto K, Kitabayashi A, Kume M, Hatano Y, Takahashi N, Iida S, Sawada K, Tagawa H.
    • Journal Title

      PLosOne

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] Therapeutic drug management of BCR-ABL tyrosine kinase inhibitor for chronic myeloid leukemia patients2013

    • Author(s)
      Miura M, Takahashi N
    • Journal Title

      Rinsho Ketsueki

      Volume: Vol.54 Pages: 1720-1729

    • NAID

      10031196316

    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Bile acid is important for gastrointestinal absorption of nilotinib.2012

    • Author(s)
      Fujimi A, Takahashi N, Miura M, Kanisawa Y, Ono K, Sawada K.
    • Journal Title

      Eur J Clin Pharmacol.

      Volume: 68 Issue: 11 Pages: 1575-6

    • DOI

      10.1007/s00228-012-1282-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Pharmacokinetics of nilotinib in imatinib-resistant/intolerant chronic myeloid leukemia patients on hemodialysis for chronic renal failure.2012

    • Author(s)
      Onaka T, Takahashi N, Miura M, Yonezawa A, Imada K, Sawada K
    • Journal Title

      Am J Hematol.

      Volume: 87 Issue: 4 Pages: 451-451

    • DOI

      10.1002/ajh.23125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Enucleation of human erythroblasts involves non-muscle myosin IIB2012

    • Author(s)
      Ubukawa K, Guo YM, Takahashi M, Hirokawa M, Michishita Y, Nara M, Tagawa H, Takahashi N, Komatsuda A, Nunomura W, Takakuwa Y, Sawada K
    • Journal Title

      Blood

      Volume: 119 Pages: 1036-44

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] Drug interaction between lenalidomide and itraconazole2012

    • Author(s)
      Takahashi N, Miura M, Kameoka Y, Abumiya M, Sawada K
    • Journal Title

      Am J Hematol

      Volume: 87 Issue: 3 Pages: 338-9

    • DOI

      10.1002/ajh.22260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Influence of H2-receptor antagonists and proton pump inhibitors on dasatinib pharmacokinetics in Japanese leukemia patients.2012

    • Author(s)
      Takahashi N, Miura M, Niioka T, Sawada K.
    • Journal Title

      Cancer Chemother Pharmacol

      Volume: 69(4) Pages: 999-1004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Pharmacokinetics of dasatinib for Philadelphia-positive acute lymphocytic leukemia with acquired T315I mutation2012

    • Author(s)
      Takahashi N, Miura M, Scott SA, Niioka T, Sawada K
    • Journal Title

      J Hematol Oncol

      Volume: 5 Issue: 1 Pages: 23-23

    • DOI

      10.1186/1756-8722-5-23

    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] H2-receptor antagonist influences dasatinib pharmacokinetics in a patient with Philadelphia-positive acute lymphoblastic leukemia2012

    • Author(s)
      Matsuoka A, Takahashi N, Miura M, Niioka T, Kawakami K, Matsunaga T, Sawada K
    • Journal Title

      Cancer Chemother Pharmacol

      Volume: 70(2) Issue: 2 Pages: 351-2

    • DOI

      10.1007/s00280-012-1900-4

    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Influence of H2-receptor antagonists and proton pump inhibitors on dasatinib pharmacokinetics in Japanese leukemia patients2012

    • Author(s)
      Takahashi N, Miura M, Niioka T, Sawada K
    • Journal Title

      Cancer Chemother Pharmacol

      Volume: 69(4) Issue: 4 Pages: 999-1004

    • DOI

      10.1007/s00280-011-1797-3

    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] A synthetic double-stranded RNA, poly I : C, induces a rapid apoptosis of human CD34(+) cells2012

    • Author(s)
      Liu J, Guo YM, Hirokawa M, Iwamoto K, Ubukawa K, Michishita Y, Fujishima N, Tagawa H, Takahashi N, Xiao W, Yamashita J, Ohteki T, Sawada K
    • Journal Title

      Exp Hematol

      Volume: 40 Pages: 330-41

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] Age-associated alteration ofγδT-cell repertoire and different profiles of activation-induced death of Vδ1 and Vδ2 T cells2011

    • Author(s)
      Michishita Y, Hirokawa M, Guo YM, Abe Y, Liu J, Ubukawa K, Fujishima N, Fujishima M, Yoshioka T, Kameoka Y, Saito H, Tagawa H, Takahashi N, Sawada K
    • Journal Title

      Int J Hematol

      Volume: 94 Pages: 230-40

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] Drug interaction of (S)-warfarin, and not (R)-warfarin, with itraconazole in a hematopoietic stem cell transplant recipient2011

    • Author(s)
      Miura M, Takahashi N, Kanno S, Kato S, Nara M, Itoh M, Saitoh H, Yoshioka T, Kameoka Y, Fujishima N, Tagawa H, Hirokawa M, Sawada K
    • Journal Title

      Clin Chim Acta

      Volume: 9;412 Pages: 2002-6

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] The role of microRNA-150 as a tumor suppressor in malignant lymphoma2011

    • Author(s)
      Watanabe A, Tagawa H, Yamashita J, Teshima K, NaraM, Iwamoto K, Kume M, Kameoka Y, Takahashi N, Nakagawa T, Shimizu N, Sawada K
    • Journal Title

      Leukemia

      Volume: 25 Pages: 1324-34

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] Quantitative determination of imatinib in human plasma with high-performance liquid chromatography and ultraviolet detection2011

    • Author(s)
      Miura M, Takahashi N, Sawada K
    • Journal Title

      J Chromatogr Sci

      Volume: 49(5) Pages: 412-5

    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Therapeutic drug monitoring of imatinib for chronic myeloid leukemia patients in the chronic phase.2011

    • Author(s)
      Takahashi N, Miura M.
    • Journal Title

      Pharmacology.

      Volume: 87(5-6) Pages: 241-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Fatal hemorrhagic pneumonia caused by Stenotrophomanas maltophilia in a patient with non-Hodgkin lymphoma2011

    • Author(s)
      Takahashi N, Yoshioka T, Kameoka Y, Tagawa H, Fujishima N, Saitoh H, Hirokawa M, Enomoto K, Sawada K
    • Journal Title

      J Infect Chemother

      Volume: 17 Pages: 858-62

    • NAID

      10030226036

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] The role of miR-150 in malignant lymphoma2011

    • Author(s)
      Waatanabe A, Tagawa H, Takahashi N, et al.
    • Journal Title

      Leukemia

      Volume: 25 Issue: 8 Pages: 1324-34

    • DOI

      10.1038/leu.2011.81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591191, KAKENHI-PROJECT-22591025, KAKENHI-PROJECT-23591365, KAKENHI-PROJECT-23701080
  • [Journal Article] Successful treatment of necrotizing fasciitis in an upper extremity caused by Clostridium perfringens after bone marrow transplantation2011

    • Author(s)
      Ito M, Takahashi N, Saitoh H, Shida S, Nagao T, Kume M, Kameoka Y, Tagawa H, Fujishima N, Hirokawa M, Tazawa H, Minato T, Yamada S, Sawada K.
    • Journal Title

      Intern Med

      Volume: 50 Pages: 2213-7

    • NAID

      130001087906

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Journal Article] Therapeutic drug monitoring of imatinib for chronic myeloid leukemia patients in the chronic phase2011

    • Author(s)
      Takahashi N, Miura M
    • Journal Title

      Pharmacology

      Volume: 87(5-6) Issue: 5-6 Pages: 241-8

    • DOI

      10.1159/000324900

    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] Quantitative determination of imatinib in human plasma with high-performance liquid chromatography and ultraviolet detection.2011

    • Author(s)
      Miura M, Takahashi N, Sawada K.
    • Journal Title

      J Chromatogr Sci.

      Volume: 49(5) Pages: 412-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Journal Article] False-positive human immunodeficiency virus antibody test and autoimmune hemolytic anemia in a patient with angioimmunoblastic T-cell lymphoma2011

    • Author(s)
      Shida S, Takahashi N, Fujishima N, Kameoka Y, Nara M, Fujishima M, Saitoh H, Tagawa H, Hirokawa M, Ichinohasama R, Sawada K
    • Journal Title

      Intern Med

      Volume: 50(20) Pages: 2383-7

    • NAID

      130001087753

    • Data Source
      KAKENHI-PROJECT-23591365
  • [Presentation] Cdc42 regulates terminal differentiation in human erythroblasts.2018

    • Author(s)
      Goto T, Ubukawa K, Asanuma K, Kobayashi I, Guo YM, Takahashi N, Wakui H, Nunomura W.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Presentation] ヒト赤芽球の終末分化におけるCdc42の情報伝達経路の解明.2018

    • Author(s)
      後藤樹史、鵜生川久美、浅沼研、小林五十鈴、郭永梅、高橋直人、涌井秀樹、布村渉
    • Organizer
      第91回日本生化学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Presentation] 移植非適応未治療多発性骨髄腫患者に対するLd療法およびレナリドミドの至適血漿中濃度の検討2017

    • Author(s)
      小林 敬宏, 三浦 昌朋, 新岡 丈典, 鐙屋 舞子, 大八木 秀明, 篠原 良徳, 茂木 睦仁, 黒木 淳, 西成 民夫, 川 端 良成, 北林 淳, 道下 吉広, 池田 翔, 志田 青慈, 吉岡 智子, 高橋 直人
    • Organizer
      日本骨髄腫学会
    • Place of Presentation
      東京
    • Year and Date
      2017-05-27
    • Data Source
      KAKENHI-PROJECT-26461414
  • [Presentation] INTERRUPTION OF CCL20-CCR6 INTERACTION INHIBITS METASTASIS OF ADVANCED CUTANEOUS T-CELL LYMPHOMA2016

    • Author(s)
      Hiroyuki Tagawa, Sho Ikeda1, Akihiro Kitadate, Naoto Takahashi, Makoto Sugaya
    • Organizer
      ヨーロッパ血液学会
    • Place of Presentation
      コペンハーゲン
    • Year and Date
      2016-06-08
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] MicroRNA-16 Mediates the Regulation of a Senescence-Apoptosis Switch in Cutaneous and other Non-Hodgkin Lymphomas.2016

    • Author(s)
      Hiroyuki Tagawa, Akihiro Kitadate, Sho Ikeda, Kazuaki Teshima, Mitsugu Ito, Naoto Takahashi, Tomomitsu Miyagaki, Sugaya Makoto
    • Organizer
      2016 Highlights of ASH in Asia.
    • Place of Presentation
      risbane Australia
    • Year and Date
      2016-03-05
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] Lenalidomide/dexamethasone salvage therapy for MM with stepwise evaluation for practical dose2016

    • Author(s)
      Reiko Watanabe, Hideo Yagi, Jian Hua, Masatomo Miura, Masao Hagihara, Naoto Takahashi, Michihide Tohuhira, Masatiro Kizaki
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] Two-year consolidation by Nilotinib might improve the TFR of STIM trial in CML with DMR2016

    • Author(s)
      Kaichi Nishiwaki, Naoto Takahashi, Chiaki Nakaseko, Hisashi Wakita, Koji Sano, Chikako Ohwada, Nobuyuki Aotsuka, Jun Kuroki, Hideo Kimura, Hideyoshi Noji, Michihide Tokuhira, Kinuko Mitani, Kazuhisa Fujikawa, Osamu Iwase, Kohshi Ohishi, Fumihiko Kimura, Tetsuya Fukuda, Sakae Tanosaki, Masatomo Miura, Kenichi Sawada
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] MicroRNA-16 mediates the regulation of a senescence-apoptosis switch in malignant lymphomas.2016

    • Author(s)
      Akihiro Kitadate, Sho Ikeda, Kazuaki Teshima, Mitsugu Ito, Naoto Takahashi, Miyagaki Tomomitsu, Makoto Sugaya, Hiroyuki Tagawa
    • Organizer
      Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics.
    • Place of Presentation
      Maui, USA
    • Year and Date
      2016-02-16
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] フィラデルフィア染色体陽性慢性骨髄性白血病患者におけるボスチニブの初期と維持期の血中濃度と効果の関係2016

    • Author(s)
      鐙屋舞子,新岡丈典,高橋直人,三浦昌朋
    • Organizer
      日本医療薬学会第26回年会
    • Place of Presentation
      京都
    • Year and Date
      2016-09-17
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] Phosphatidylinositol phosphates profile reveals distinct subtypes of malignant lymphomas.2015

    • Author(s)
      阿部史人, 田川博之, 北舘明宏, 池田翔, 奈良美保, 亀岡吉弘, 高橋直人, 佐々木雄彦, 中西広樹
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] Silencing progression of tumor suppressive microRNAs essentially contributes to develop aggressive T-cell lymphoma.2015

    • Author(s)
      Akihiro Kitadate, Mitsugu Ito, Sho Ikeda, Kazuaki Teshima, Naoko Hasunuma, Tomomitsu Miyagaki, Sugaya Makoto, Naoto Takahashi, Atsushi Komatuda , Hiroyuki Tagawa
    • Organizer
      20th Congress of the European Hematology Association. (Abstract #E1361)
    • Place of Presentation
      Vienna, Austla
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] Correlation of dasatinib pharmacokinetics with clinical response and adverseevents2015

    • Author(s)
      Akiko Mita, Masatomo Miura, Takenori Niioka, Maiko Abumiya Takahiro Kobayashi, Saori Takahashi, Yoshihiro Kameoka, Tomoko Yoshioka, Naoto Takahashi
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] MicroRNA-16 Mediates the Regulation of a Senescence-Apoptosis Switch in Cutaneous and other Non-Hodgkin Lymphomas.2015

    • Author(s)
      Akihiro Kitadate, Sho Ikeda, Kazuaki Teshima, Mitsugu Ito, Naoto Takahashi, Tomomitsu Miyagaki, Sugaya Makoto, Hiroyuki Tagawa
    • Organizer
      57th American Society of Hematology Annual Meeting & Exposition. (Abstarct #468)
    • Place of Presentation
      Orland USA
    • Year and Date
      2015-12-07
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] 膠原病患者におけるタクロリムスとイトラコナゾールとの薬物相互作用に及ぼすCYP3A5およびABCB1遺伝子多型の影響2015

    • Author(s)
      新岡丈典, 富樫賢, 小松田敦, 奈良瑞穂, 奥山慎, 面川歩, 鐙屋舞子, 涌井秀樹, 高橋直人, 三浦昌朋
    • Organizer
      日本医療薬学会第25回年会
    • Place of Presentation
      横浜
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] Influence of CYP3A5 gene polymorphisms on pharmacokinetics of tacrolimus modified-release once-daily after hematopoietic stem cell transplantation.2015

    • Author(s)
      Takaya Yamashita, Naohito Fujishima, Masatomo Miura, Takenori Niioka, Maiko Abumiya, Kazuaki Teshima, Kumi Ubukawa, Miho Nara, Masumi Fujishima, Yoshihiro Kameoka, Makoto Hirokawa, Naoto Takahashi
    • Organizer
      20th Congress of European Hematology Association
    • Place of Presentation
      Vienna
    • Year and Date
      2015-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] Tumor-suppressor miR-16 induces senescence and apoptosis in aggressive T-cell lymphomas2015

    • Author(s)
      北舘明宏、池田翔、奈良美保、 鵜生川久美、渡部敦、藤島真澄、藤島直仁、吉岡智子、 亀岡吉弘、 高橋直人、宮垣朝光、 菅谷誠、 田川博之
    • Organizer
      第77回日本血液学会学術総会 (演題番号OS-3-131、抄録p424)
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-18
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] Pharmacokinetics of bosutinib and its induced-diarrhea in Ph-positive chronic myeloid leukemia2015

    • Author(s)
      Maiko Abumiya, Naoto Takahashi, Takenori Niioka, Saori Takahashi, Akiko Mita, Takahiro Kobayashi, Yoshihiro Kameoka, Tomoko Yoshioka, Naohito Fujishima, Hiroyuki Tagawa, Kenichi Sawada, Masatomo Miura
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] Restoration of tumor-suppressive miRNAs induces senescence, apoptosis and metastasis inhibition in aggressive T-cell lymphomas2015

    • Author(s)
      北舘明宏、池田翔、伊藤貢、手島和暁、阿部史人、奈良美保、渡部敦、亀岡吉弘、高橋直人、田川博之
    • Organizer
      第74回日本癌学会学術総会(演題番号P-3227、抄録p284)
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-25461405
  • [Presentation] Clarithromycin Elevates the Plasma Concentration of Lenalidomide Via Inhibition of MDR1.2014

    • Author(s)
      Naoki Takezako, Masatomo Miura, Akihisa Nagata, Naohiro Sekiguchi, Takenori Niioka, Seiji Shida, Takahiro Kobayashi, Maiko Abumiya, Akiyoshi Miwa, Naoto Takahashi
    • Organizer
      56th American Society of Hematology Annual Meeting and Exposition
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] レナリドマイドのTDMの有用性~TM-Rev 試験からの報告2014~2014

    • Author(s)
      新岡丈典、高橋直人、志田青慈、小林敬宏、鐙屋舞子、澤田賢一、三浦昌朋
    • Organizer
      医療薬学フォーラム2014/第22回クリニカルファーマシーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-06-28
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] Blood concentration of lenalidomide would change with the existence of clarithromycin.2014

    • Author(s)
      Naoki Takezako, Naohiro Sekiguchi, Akihisa Nagata, Masatomo Miura, Tekenori Niioka, Seiji Shida, Takahiro Kobayashi, Maiko Abumiya, Naoto Takahashi
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] Pharmacokinetcis of lenalidomide in patients with multiple myeloma on hemodialysis.2014

    • Author(s)
      Takahiro Kobayashi, Naoto Takahashi, Masatomo Miura, Ayano Ohara, Yoshihiro Mitishita, Tekenori Niioka, Maiko Abumiya, Seiji Shida, Kumi Ubukawa, Naohito Fujishima, Yoshihiro Kameoka, Hiroyuki Tagawa, Kenichi Sawada
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31
    • Data Source
      KAKENHI-PROJECT-26460188
  • [Presentation] Inter- and intra-individual variability of nilotinib plasma trough concentration in CML patients2013

    • Author(s)
      Abumiya M, Miura M, Takahashi N, Niioka T, Sawada K
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Presentation] Inter- and intra-individual variability of nilotinib plasma trough concentration in CML patients.2013

    • Author(s)
      2) Maiko Abumiya, Masatomo Miura, Naoto Takahashi, Takenori Niioka, Kenichi Sawada
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Presentation] Multicenter Phase II Clinical Trial of Nilotinib for Patients with Imatinib-Resistant or Intolerant CML from the East Japan CML Study Group (EJCML) Trial : Evaluation of Molecular Responses by the BCR-ABL1 Mutational Status and Plasma Trough Concentration of Nilotinib2012

    • Author(s)
      Takahashi N, Miura M, et al
    • Organizer
      54th American Society of Hematology Annual Meeting and Exposition
    • Place of Presentation
      Atlanta
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Presentation] ダサチニブと胃酸分泌抑制剤との相互作用2012

    • Author(s)
      三浦昌朋,高橋直人,新岡丈典,澤田賢一
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Presentation] Multicenter phase II clinical trial of Nilotinib for patients with Imatinib-resistance or -intolerant CML from the East Japan CML Study Group (EJCML): Evaluation of molecular response by BCR-ABL1 mutation status and plasma trough concentration of Nilotinib2012

    • Author(s)
      Takahashi N, Miura M, Niioka T, et al
    • Organizer
      ASH Annual Meeting
    • Place of Presentation
      アトランタ
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Presentation] 経口分子標的治療薬の個別化治療2012

    • Author(s)
      三浦昌朋,高橋直人
    • Organizer
      第33回日本臨床薬理学会学術総会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-23590168
  • [Presentation] 遺伝子多型情報とTDMに基づいたイマチニブ個別化療法2011

    • Author(s)
      三浦 昌朋、高橋 直人
    • Organizer
      第28回 日本TDM学会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23590168
  • 1.  MIURA MASATOMO (30265194)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 44 results
  • 2.  TAGAWA Hiroyuki (30373492)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 22 results
  • 3.  TSUCHIYA Norihiko (70282176)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  Kagaya Hideaki
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  SATO Kazuhiro (30436191)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  Shibata Hiroyuki (60393732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Niioka Takenori (20722276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  SATOH Shigeru (80187195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Ubukawa Kumi (70646554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  横山 和明 (00647498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  大場 雄介 (30333503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Abumiya Maiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 13.  ICHINOHASAMA Ryo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  鵜生川 久美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 15.  石澤 賢一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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