Kotani Joji 小谷穣治

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KOTANI Joji 小谷穣治

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Researcher Number	80360270
Other IDs
External Links
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 神戸大学, 医学部附属病院, 教授 2009 – 2016: Hyogo College of Medicine, 医学部, 教授 2007 – 2008: Hyogo College of Medicine, 医学部, 准教授 2004 – 2005: 兵庫医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related Except Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator IL-18 / 敗血症 / 好中球 / 性差 / エンドトキシン / アポトーシス / 集中治療医学 / 筋肉萎縮 / PICS(集中治療後症候群) / PICS … More / 筋肉 / interleukin-18 / 脳内炎症 / アストロサイト / T細胞 / 長期予後 / 敗血症後症候群 / 敗血症性脳症 / インターロイキン18 / 肺傷害 / Interleukin-18 / 敗血症、 / tumor necrosis factor / rat / mouse / popy unsaturated fatty acids / endotoxin / bone marrow cells / neutrophil / TNF receptor / TNF / 中心静脈栄養 / Tumor necrosis factor / ラット / マウス / 不飽和脂肪酸 / 骨髄細胞 / 一塩基多型 / 遺伝子多型 / 血糖値 / インスリン / 静脈投与 / 侵襲 / 魚油 / 骨髄 / 外科侵襲 … More Except Principal Investigator 敗血症 / 脳内炎症 / 加齢 / 集中治療後症候群 / リンパ球 / 精神障害 / 身体機能障害 / 敗血症性脳症 / 敗血症、 / 肺障害 / 出血性ショック / 水素 / ペプチドーム解析 / 播種性血管内凝固症候群 / ショック / ペプチドマーカー / 血管内凝固症候群 / 循環不全 / TLR / 腸管免疫 / 外科侵襲 / IL-18 / エンドトキシン / アポトーシス / 腸管粘膜 / TIRレセプターファミリー / 集中治療医学 Less

PICSにおける好中球の筋肉内浸潤の病態解明と好中球遊走制御による新たな治療法の確立Principal Investigator
- Principal Investigator
  
  小谷穣治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kobe University
A therapeutic strategy of post-intensive care syndrome focused on its mechanism and inflammation regulation in brain.
- Principal Investigator
  
  Inoue Shigeaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kobe University
IL-18 as a therapeutic target for sepsis-associated encephalopathy and long-term prognosis of septic mousePrincipal Investigator
- Principal Investigator
  
  Joji Kotani
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kobe University
Possibility of IL-18 as a therapeutic target to improve outcomes of sepsis in malePrincipal Investigator
- Principal Investigator
  
  KOTANI JOJI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Kobe University
  Hyogo Medical University
Development of useful biomarkers for diagnosis of septic shock by using a new method for peptidome analysis
- Principal Investigator
  
  Wakabayashi Ichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo Medical University
The relationship between IL-18 polymorphism and gender difference in emergency intensive care unitPrincipal Investigator
- Principal Investigator
  
  Kotani Joji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo Medical University
Hydrogen Inhalation Protects Against Acute Lung Injury Induced by Hemorrhagic Shock and Resuscitation
- Principal Investigator
  
  Nakao Atsunori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo Medical University
The effect of IL-18 and gender difference on inflammation-related insulin resistance.Principal Investigator
- Principal Investigator
  
  KOTANI Joji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo Medical University
魚油の静脈投与による侵襲下好中球アポトーシス抑制の解除と組織障害軽減の研究Principal Investigator
- Principal Investigator
  
  小谷穣治
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo Medical University
The role of TIR family receptors in the induction of apoptosis of bone marrow cells and the immunosuppression after the endotoxinemia.Principal Investigator
- Principal Investigator
  
  KOTANI Joji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo College of Medicine
The role of TIR family receptors in the apoptosis of the intestinal epithelium under endotoxinemia.
- Principal Investigator
  
  TERASHIMA Mariko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo College of Medicine
The role of Il-18 In Inducing or preventing apoptosis in neutrophils during acute endotoxemiaPrincipal Investigator
- Principal Investigator
  
  KOTANI Joji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Hyogo College of Medicine

[Book] 経腸栄養剤ハンドブック AtoZ 各種病態における経腸栄養剤の選び方と使い方10)高度侵襲症例.2009
- Author(s)
  小谷穣治
- Total Pages
  216
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21659419
[Book] イラストで学ぶクリティカルケアー基本手技とモニタリング2004
- Author(s)
  丸川征四郎, 小谷穣治
- Total Pages
  248
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] Sepsis Induces Physical and Mental Impairments in a Mouse Model of Post-Intensive Care Syndrome2021
- Author(s)
  Yoshihisa Fujinami, Shigeaki Inoue, Yuko Ono, Yusuke Miyazaki, Kazumichi Fujioka, Kimihiro Yamashita, Joji Kotani
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 8 Pages: 1593-1593
- DOI
  10.3390/jcm10081593
- NAID
  120007035637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09414, KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-20H03781, KAKENHI-PROJECT-20K08229
[Journal Article] Malocclusion of Molar Teeth Is Associated with Activities of Daily Living Loss and Delirium in Elderly Critically Ill Older Patients2021
- Author(s)
  Fujinami Yoshihisa、Hifumi Toru、Ono Yuko、Saito Masafumi、Okazaki Tomoya、Shinohara Natsuyo、Akiyama Kyoko、Kunikata Misa、Inoue Shigeaki、Kotani Joji、Kuroda Yasuhiro
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 10 Pages: 2157-2157
- DOI
  10.3390/jcm10102157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-20H03781
[Journal Article] Infiltrated regulatory T cells and Th2 cells in the brain contribute to attenuation of sepsis-associated encephalopathy and alleviation of mental impairments in mice with polymicrobial sepsis2020
- Author(s)
  Saito M, Fujinami Y, Ono Y, Ohyama S, Fujioka K, Yamashita K, Inoue S, Kotani J
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 92 Pages: 25-38
- DOI
  10.1016/j.bbi.2020.11.010
- NAID
  120006993636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09414, KAKENHI-PROJECT-20K08229, KAKENHI-PROJECT-18K16544, KAKENHI-PROJECT-20H03781
[Journal Article] Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation.2015
- Author(s)
  Kohama K, Yamashita H, Aoyama-Ishikawa M, Takahashi T, Billiar TR, Nishimura T, Kotani J, Nakao A
- Journal Title
  
  Surgery
  
  Volume: 158(2) Issue: 2 Pages: 399-407
- DOI
  10.1016/j.surg.2015.03.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462840
[Journal Article] IL18 production and IL18 promoter polymorphisms correlate with mortality in ICU patients.2014
- Author(s)
  Yamada T, Aoyama-Ishikawa M, Yamashita H, Fujiwara M, Usami M, Ueda T, Terashima M, Kohama K, Nakao A, Kotani J.
- Journal Title
  
  In Vivo
  
  Volume: 28 Pages: 391-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462841
[Journal Article] A simple scoring system based on neutrophil count in sepsis patients.2014
- Author(s)
  Ueda T, Aoyama-Ishikawa M, Nakao A, Yamada T, Usami M, Kotani J.
- Journal Title
  
  Med Hypotheses
  
  Volume: 82 Issue: 3 Pages: 382-386
- DOI
  10.1016/j.mehy.2014.01.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462841
[Journal Article] 血糖管理による生体反応の制御はどこまで可能か？2013
- Author(s)
  石川（青山）　倫子,　小谷　穣治
- Journal Title
  
  侵襲と免疫
  
  Volume: 22巻
- Data Source
  KAKENHI-PROJECT-23659852
[Journal Article] 血糖管理による生体反応の制御はどこまで可能か2013
- Author(s)
  石川(青山)倫子、小谷穣治
- Journal Title
  
  侵襲と免疫
  
  Volume: 22巻 Pages: 48-50
- Data Source
  KAKENHI-PROJECT-23659852
[Journal Article] 免疫能を考慮した経腸栄養法-免疫増強・免疫調節の観点から-2010
- Author(s)
  小谷穣治
- Journal Title
  
  CCU
  
  Volume: 34 Pages: 205-212
- Data Source
  KAKENHI-PROJECT-21659419
[Journal Article] 栄養管理のプランニングと評価2009
- Author(s)
  小谷穣治、橋本篤徳、尾迫貴章、蔭山晶子、木下理恵、上田敬博
- Journal Title
  
  救急医学 33
  
  Pages: 1751-1756
- Data Source
  KAKENHI-PROJECT-21659419
[Journal Article] 重症病態における経腸栄養.2009
- Author(s)
  小谷穣治
- Journal Title
  
  臨床栄養 114
  
  Pages: 666-675
- Data Source
  KAKENHI-PROJECT-21659419
[Journal Article] Gender difference in granulocyte dynamics and apoptosis and the role of IL-18 during endotoxin-induced systemic inflammation2009
- Author(s)
  Aoyama M, Kotani J, Usami M
- Journal Title
  
  Shock (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592104
[Journal Article] 重症救急患者における早期経腸栄養法(early enteral feeding in critically ill patients).特集消化器外科における経腸栄養の意義と役割.2009
- Author(s)
  小谷穣治、橋本篤徳、寺嶋真理子、山田太平、上田敬博.
- Journal Title
  
  臨床外科 64
  
  Pages: 1385-1395
- Data Source
  KAKENHI-PROJECT-21659419
[Journal Article] 侵襲下における骨髄細胞アポトーシスとTNFレセプターの役割-好中球への成熟に伴う変化-2006
- Author(s)
  小谷穣治
- Journal Title
  
  侵襲と免疫 15・1
  
  Pages: 37-40
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] Tumor necrosis factor receptor regulation of bone marrow cell apoptosis during endotoxin-induced systemic inflammation.2006
- Author(s)
  Joji Kotani, Nicholas J.Avallon, Edward Lin, Masahiro Goshima, Stephen F.Lowry, Steve E.Calvano.
- Journal Title
  
  Shock (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] 腸管上皮細胞におけるToll-likereceptorsの役割2006
- Author(s)
  小谷穣治
- Journal Title
  
  日本外科代謝・栄養 39・4
  
  Pages: 165-177
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] Tumor necrosis factor receptor regulation of bone marrow cell apoptosis during endotoxin-induced systemic inflammation2006
- Author(s)
  Joji Kotani
- Journal Title
  
  Shock 25(5)
  
  Pages: 464-471
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] 腸管上皮細胞におけるToll-like receptorsの役割2006
- Author(s)
  小谷穣治
- Journal Title
  
  日本外科代謝・栄養 39・4
  
  Pages: 165-177
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] 侵襲下における骨髄細胞アポトーシスとTNFレセプターの役割.-好中球への成熟に伴う変化-2006
- Author(s)
  小谷穣治.
- Journal Title
  
  侵襲と免疫 15(1)
  
  Pages: 37-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] The roles of toll-like receptors in gut epithelium.2005
- Author(s)
  Joji Kotani, Masahiro Goshima, Michiko Aoyama, Manabu Kirita, Makoto Usami, Seishiro Marukawa.
- Journal Title
  
  JSME 39(4)
  
  Pages: 165-177
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] The mechanisms of organ dysfunction during severe infection.2005
- Author(s)
  Joji Kotani, Jun-ichi Hirata, Masahiro Goshima, MD, PhD, Mariko Yamada, Munenori Matsudaira, Munehiko Ohya, Manabu Kirita, Kazumasa Yoshinaga, Seishiro Marukawa.
- Journal Title
  
  日本腹部救急医学会雑誌 25(5)
  
  Pages: 718-720
- NAID
  130004243455
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] 重症感染症における臓器障害の発生機序2005
- Author(s)
  小谷穣治
- Journal Title
  
  日本腹部救急医学会雑誌 25・5
  
  Pages: 713-720
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] ROLE OF INTERLEUKIN 18 IN NITRIC OXIDE PRODUCTION AND PANCREATIC DAMAGE DURING ACUTE PANCREATITIS2005
- Author(s)
  Naoko Ueno, Shin-ichiro Kashiwamura, Haruyasu Ueda, Haruki Okamura, Noriko M. Tsuji, Katsushi Hosohara, Joji Kotanii, Seishiro Marukawa.
- Journal Title
  
  Shock 24(6)
  
  Pages: 564-570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] Apoptosis And Bcl-2 Protein Family Expression In Neutrophils During Experimental Human Endotoxemia And Clinical2005
- Author(s)
  Joji Kotani
- Journal Title
  
  Shock 23・suppl
  
  Pages: 58-59
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] APOPTOSIS AND BCL-2 PROTEIN FAMILY EXPRESSION IN NEUTROPHILS DURING EXPERIMENTAL HUMAN ENDOTOXEMIA AND CLINICAL SEPSIS.2005
- Author(s)
  J Kotani*, E Lin*, N Avallone*, M Goshima*, S Calvano, S Lowry.
- Journal Title
  
  Shock 23, Supple 3
  
  Pages: 58-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] Apoptosis And Bcl-2 Protein Family Expression In Neutrophils During Experimental Human Endotoxemia And Clinical Sepsis.2005
- Author(s)
  Joji Kotani
- Journal Title
  
  Shock 23・suppl3
  
  Pages: 58-59
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] Tumor necrosis factor receptor regulation of bone marrow cell apoptosis during endotoxin-induced systemic inflammation
- Author(s)
  Joji Kotani
- Journal Title
  
  Shock (in press)
- Data Source
  KAKENHI-PROJECT-16591818
[Journal Article] Gender difference in granulocyte dynamics and apoptosis and the role of IL-18 during endotoxin-induced systemic inflammation
- Author(s)
  Aoyama M, Kotani J, Usami M
- Journal Title
  
  Shock in press
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592104
[Presentation] 敗血症後、制御性T細胞はどのように脳に増加するのか -制御性T細胞の供給源としての頸部リンパ節の役割-2022
- Author(s)
  齋藤雅史、大野雄康、藤浪好寿、森山直紀、宮崎勇輔、中西信人、山下公大、井上茂亮、小谷穣治
- Organizer
  第36回日本Shock学会
- Data Source
  KAKENHI-PROJECT-19K09414
[Presentation] 敗血症モデルマウスにおいて、脳内に浸潤したT細胞は敗血症性脳症とそれに伴う不安様行動の回復を促進する2021
- Author(s)
  齋藤雅史、藤浪好寿、大野雄康、大山正平、藤岡一路、山下公大、井上茂亮、小谷穣治
- Organizer
  第58回外科代謝栄養学会
- Data Source
  KAKENHI-PROJECT-19K09414
[Presentation] 敗血症マウスの脳内に浸潤したT細胞は、敗血症性脳症を抑制し、精神障害の回復を促進する2021
- Author(s)
  齋藤雅史、藤浪好寿、大野雄康、大山正平、藤岡一路、山下公大、井上茂亮、小谷穣治
- Organizer
  第35回日本Shock学会
- Data Source
  KAKENHI-PROJECT-19K09414
[Presentation] CX3CR1high macrophage and Treg in the brain may help to improve anxiety-like behavior in septic mice2021
- Author(s)
  Masafumi Saito, Yoshihisa Fujinami, Yuko Ono, Nobuto Nakanishi, Kimihiro Yamashita, Shigeaki Inoue, Joji Kotani
- Organizer
  16th International Endotoxin and Innate Immunity Society
- Data Source
  KAKENHI-PROJECT-19K09414
[Presentation] Sepsis impairs physical, cognitive and mental function in aged mice2019
- Author(s)
  Masafumi Saito, Shigeaki Inoue, Yoshihisa Fujinami, Shohei Ohyama, Yuko Ono, Joji Kotani
- Organizer
  International Federation of Shock Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09414
[Presentation] 敗血症性脳症マウスモデルの構築とその評価2019
- Author(s)
  齋藤雅史、井上茂亮、大山正平、藤浪好寿、大野雄康、小谷穣治
- Organizer
  日本エンドトキシン・自然免疫研究会
- Data Source
  KAKENHI-PROJECT-19K09414
[Presentation] 敗血症は脳内のAstrocyteやMicrogliaを減少させ、不安様行動を増悪させる。 -敗血症性脳症マウスモデルを用いた基礎的な検討-2019
- Author(s)
  齋藤雅史、井上茂亮、大山正平、藤浪好寿、大野雄康、小谷譲治
- Organizer
  日本集中治療医学会
- Data Source
  KAKENHI-PROJECT-19K09414
[Presentation] IL18 Production and IL18 Promoter Polymorphisms Correlate with Mortality in ICU Patients2015
- Author(s)
  Taihei Yamada, Atsunori Nakao, Takaaki Osako, Hiroyuki Sakata, Michiko Ishikawa Aoyama, Hayato Yamashita, Makoto Usami, Takahiro Ueda, Keisuke Kohama, Joji Kotani
- Organizer
  8th Asian Conference for Emergency Medicine
- Place of Presentation
  Taipei International Convention Center (Taipei, China)
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462841
[Presentation] 1.3%水素吸入は出血性ショック蘇生後急性肺障害を軽減する2015
- Author(s)
  山下勇人、小濱圭祐、石川倫子、西村健、藤崎宣友、宇佐美眞、小谷穣治、中尾篤典
- Organizer
  第30回日本Shock学会総会
- Place of Presentation
  京王プラザホテル八王子(東京都、八王子市)
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-25462840
[Presentation] IL-18 supresed hyperglycemia in hyperacute phase of endotoxemia2013
- Author(s)
  Hayato Yamashita, Michiko Aoyama-Ishikawa, Taketo Inoue, Makoto Miyoshi, Noriaki Maeshige, Yasuhiko Okimura, Makoto Usami, Joji Kotani.
- Organizer
  The 35 th Congress of the European Society of Parenteral and Enteral Nutrition.
- Place of Presentation
  Germany
- Year and Date
  2013-09-14
- Data Source
  KAKENHI-PROJECT-23659852
[Presentation] マウス急性エンドトキシン血症下の高血糖へ及ぼすIL-18の関与の検討2013
- Author(s)
  山下勇人、青山倫子、高原美樹、山内千里、岡伸樹、井上岳人、前重伯壮、三好真琴、置村康彦、宇佐美眞、小谷穣治
- Organizer
  第28回日本Shock学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659852
[Presentation] エンドトキシン血症下の血糖変動とインスリンシグナルへのIL-18の役割2012
- Author(s)
  青山倫子,高原美樹,山内千里,宇佐美眞,小谷穣治
- Organizer
  第27回日本Shock学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659852
[Presentation] 急性炎症下における血糖変動へのIL-18の関与2012
- Author(s)
  山下勇人,青山倫子,高原美樹,山内千里,置村康彦,宇佐美眞,小谷穣治
- Organizer
  第19回外科侵襲とサイトカイン研究会
- Place of Presentation
  神戸
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-23659852
[Presentation] Gender differences in neutrophil apoptosis, blood corticosterone, insulin and glucose levels2011
- Author(s)
  Chisato Yamauchi, Michiko Aoyama, MikiTakahara, Noriaki Maeshige, Makoto Miyoshi, Yasuhiko Okimura, Joji Kotani, Makoto Usami.
- Organizer
  The 33th Congress of the European Society of Parenteral and Enteral Nutrition.
- Place of Presentation
  Sweden, Goteborgs
- Data Source
  KAKENHI-PROJECT-23659852
[Presentation] N-3多価不飽和脂肪酸(PUFAs)静脈投与による全身炎症下末梢血および骨髄好中球(PMN)アポトーシス(Ap)抑制解除2011
- Author(s)
  小谷穣治
- Organizer
  第26回日本静脈経腸栄養学会
- Place of Presentation
  名古屋
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 免疫修飾栄養素を用いた重症患者の栄養管理-最近のトピックスと我々の工夫-2010
- Author(s)
  小谷穣治
- Organizer
  第23回日本熱傷学会甲信地方会学術集会
- Place of Presentation
  甲府(招待講演)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] The effect of parenteral nutrition with n-3 polyunsaturated fatty acids-enriched lipids on neutrophil apoptosis in the peripheral blood and bone marrow during endotoxin-induced systemic inflammation.2010
- Author(s)
  Joji Kotani
- Organizer
  2010 annual meeting of the Southern International Symposium of Parenteral & Enteral Nutrition (SISPEN)
- Place of Presentation
  Guangzhou(広州)(Invited Speaker 招待講演)
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 重症患者における免疫栄養素と経腸栄養剤による免疫修飾効果2009
- Author(s)
  小谷穣治
- Organizer
  より良きCritical Care」を考える合同セミナー
- Place of Presentation
  吹田
- Year and Date
  2009-11-09
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 重症病態における代謝栄養管理-最近の理論と実践-2009
- Author(s)
  小谷穣治
- Organizer
  第18回外科はりまの会研究会
- Place of Presentation
  姫路
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 重症病態における栄養管理2009
- Author(s)
  小谷穣治
- Organizer
  第二回岐阜外傷カンファレンス
- Place of Presentation
  岐阜
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 重症病態における栄養管理:最近のトピックスと我々の工夫2009
- Author(s)
  小谷穣治
- Organizer
  多摩栄養サポート研究会
- Place of Presentation
  立川
- Year and Date
  2009-10-07
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 重症患者の代謝栄養管理-最近のトピックスと我々の工夫2009
- Author(s)
  小谷穣治
- Organizer
  第18回兵庫県救急・集中治療研究会
- Place of Presentation
  神戸
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 魚油とARDS-その関係は?-2009
- Author(s)
  小谷穣治
- Organizer
  第3回阪神呼吸器フォーラム
- Place of Presentation
  大阪
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] 臨床に必要な水・電解質、栄養の知識2009
- Author(s)
  小谷穣治
- Organizer
  福岡大学病院NST学術集会講演(特別講演)
- Place of Presentation
  福岡
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-21659419
[Presentation] エンドトキシン血症下の骨髄細胞のアポトーシスにおけるIL-18の役割の雌雄差2008
- Author(s)
  青山倫子、小谷穣治、宇佐美眞、丸川征四郎
- Organizer
  第15回外科侵襲とサイトカイン研究会
- Place of Presentation
  岩手県
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19592104
[Presentation] The role of IL-18 in apoptosis induction of bone marrow granulocytes during systemic inflammation in mice.2008
- Author(s)
  Aoyama M, Kotani J, Usami M, Marukawa S.
- Organizer
  第31回アメリカショック学会、第6回国際ショック学会(共同開催)
- Place of Presentation
  ドイツ
- Year and Date
  2008-07-01
- Data Source
  KAKENHI-PROJECT-19592104
[Presentation] エンドトキシン(Etx)血症下のマウス腸管における apoptosisへのInterleukin (IL)-18の影響2008
- Author(s)
  小坂宮, 青山倫子, 小谷穣治, 丸川征四郎
- Organizer
  第15回外科侵襲とサイトカイン研究会
- Place of Presentation
  岩手県
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19659475
[Presentation] エンドトキシン血症下の骨髄細胞のアポトーシスにおける1L-18の役割の雌雄差2008
- Author(s)
  青山倫子, 小谷穣治, 宇佐美眞, 丸川征四郎
- Organizer
  第15回外科侵襲とサイトカイン研究会
- Place of Presentation
  岩手県
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19592104
[Presentation] The role of IL-18 in apoptosis induction of bone marrow granulocytes during systemic inflammation in mice2008
- Author(s)
  Aoyama M, Kotani J, Usami M, Marukawa S
- Organizer
  第31回アメリカショック学会第6回国際ショック学会(共同開催)
- Place of Presentation
  ドイツ(ケルン)
- Year and Date
  2008-07-01
- Data Source
  KAKENHI-PROJECT-19592104
[Presentation] Hydrogen Inhalation Protects Against Acute Lung Injury Induced by Hemorrhagic Shock and Resucitation
- Author(s)
  Keisuke Kohama, Hayato Yamashita, Michiko Aoyama-Ishikawa, Takeshi Nishimura, Noritomo Fujisaki, Joji Kotani, Atsunori Nakao
- Organizer
  10th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas Nevada,America
- Year and Date
  2015-02-03 – 2015-02-05
- Data Source
  KAKENHI-PROJECT-25462840
[Presentation] 血中IL18濃度とIL18プロモーター領域遺伝子多型はICU患者における死亡率と相関する
- Author(s)
  山田太平、小濱圭祐、寺嶋真理子、上田敬博、中尾篤典、小谷穣治
- Organizer
  第42回日本救急医学会総会・学術集会
- Place of Presentation
  福岡
- Year and Date
  2014-10-28 – 2014-10-30
- Data Source
  KAKENHI-PROJECT-25462841

1. AOYAMA Michiko (40566121)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. USAMI Makoto (00193855)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MARUKAWA Seichirou (00030883)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. TERASHIMA Mariko (00412015)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. OYA Munehiko (40309480)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. UEDA Takahiro (80412055)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NAKAO Atsunori (40648169)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. Inoue Shigeaki (30582209)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 西田修 (20208185)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 酒井良忠 (90397802)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KIRITA Manabu (40289062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UEDA Takahiro (80312055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. OKIMURA Yasuhiko (30204100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. KUBOYAMA Kazutoshi (00299116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YAMADA Isamu (20593990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. MIYAWAKI Atsushi (90418963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HASHIMOTO Atsunori (50461083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Wakabayashi Ichiro (70220829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OKAMURA Haruki (60111043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 丸茂幹雄 (40333950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 細原勝士 (40368527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 松本理器 (00378754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 曽良一郎 (40322713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 黒田泰弘 (80234615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 山下公大 (80535427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 宇佐美真

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
27. 大野雄康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kotani Joji 小谷 穣治

KOTANI Joji 小谷 穣治

Research Projects

Research Products

Co-Researchers

PICSにおける好中球の筋肉内浸潤の病態解明と好中球遊走制御による新たな治療法の確立Principal Investigator

Principal Investigator

Project Period (FY)

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A therapeutic strategy of post-intensive care syndrome focused on its mechanism and inflammation regulation in brain.

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

IL-18 as a therapeutic target for sepsis-associated encephalopathy and long-term prognosis of septic mousePrincipal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Possibility of IL-18 as a therapeutic target to improve outcomes of sepsis in malePrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Development of useful biomarkers for diagnosis of septic shock by using a new method for peptidome analysis

Principal Investigator

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Research Field

Research Institution

The relationship between IL-18 polymorphism and gender difference in emergency intensive care unitPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hydrogen Inhalation Protects Against Acute Lung Injury Induced by Hemorrhagic Shock and Resuscitation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of IL-18 and gender difference on inflammation-related insulin resistance.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

魚油の静脈投与による侵襲下好中球アポトーシス抑制の解除と組織障害軽減の研究Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The role of TIR family receptors in the induction of apoptosis of bone marrow cells and the immunosuppression after the endotoxinemia.Principal Investigator

Principal Investigator

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Research Field

Research Institution

The role of TIR family receptors in the apoptosis of the intestinal epithelium under endotoxinemia.

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

The role of Il-18 In Inducing or preventing apoptosis in neutrophils during acute endotoxemiaPrincipal Investigator

Principal Investigator

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Research Institution

[Book] 経腸栄養剤ハンドブック AtoZ 各種病態における経腸栄養剤の選び方と使い方10)高度侵襲症例.2009

Author(s)

Total Pages

Kotani Joji 小谷穣治

KOTANI Joji 小谷穣治

[Book] イラストで学ぶクリティカルケアー基本手技とモニタリング2004

[Journal Article] 重症救急患者における早期経腸栄養法(early enteral feeding in critically ill patients).特集消化器外科における経腸栄養の意義と役割.2009