Nakagawa Yoshimi 中川嘉

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NAKAGAWA Yoshimi 中川嘉

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Researcher Number	80361351
Other IDs	https://orcid.org/0000-0001-8710-5232
Affiliation (Current)	2022: 富山大学, 学術研究部薬学・和漢系, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 富山大学, 学術研究部薬学・和漢系, 教授 2014 – 2021: 筑波大学, 国際統合睡眠医科学研究機構, 准教授 2014: 筑波大学, 学内共同利用施設等, 准教授 2014: 筑波大学, 医学医療系, 准教授 2011 – 2013: 筑波大学, 医学医療系, 講師 … More 2007 – 2011: University of Tsukuba, 大学院・人間総合科学研究科, 講師 2006: University of Tsukuba., Graduate School of Comprehensive Human Sciences, Assist. Prof., 大学院人間総合科学研究科, 講師 2005: 筑波大学, 大学院・人間総合科学研究科, 研究員 2004: 筑波大学, 大学院・人間総合科学研究科, 助手 2003: 筑波大学, 臨床医学系, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Applied health science / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / 基礎ゲノム科学 / Applied health science / Biological Sciences Except Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related / Applied health science / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields … More / Biological Sciences / Applied health science / Sports science / Integrated Nutrition Science / Pathological medical chemistry / Complex systems / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Complex Systems Disease Theory / General pharmacology Less
Keywords	Principal Investigator 生活習慣病 / 脂質代謝 / 遺伝子発現 / CREBH / 糖尿病 / 糖代謝 / 転写因子 / FGF21 / インスリン / エネルギー代謝 … More / 転写調節 / 栄養代謝 / コレステロール代謝 / 横紋筋融解症 / 動脈硬化 / 非アルコール性脂肪肝 / SREBP / 小腸構造 / 腸内細菌叢 / IRS-2 / 高脂血症 / グルコース / 肝臓 / 機能性RNA / 転写制御 / miRNA / 遺伝子発現制御 / 脂肪分化 / TFE3 / PPARα / 骨格筋 / ゲノム編集 / 肥満 / スタチン / HMGCR / 腸肝循環 / CRISPR/Cas9システム / 肝がん / 慢性炎症 / CRISPR/Cas9 / 脂質 / 栄養学 / SREBP-1a / 脂肪酸合成 / 小腸の発生・分化 / 発生・分化 / 肝臓がん / 栄養吸収 / 成長ホルモン抵抗性 / IGF1 / 食餌誘導性肝がん / 腸肝連関 / 腸管免疫 … More Except Principal Investigator 生活習慣病 / 脂肪酸 / 糖尿病 / 転写因子 / コレステロール / 脂質代謝 / 脂質 / インスリン抵抗性 / SREBP / TFE3 / 骨格筋 / 遺伝子発現 / メタボリックシンドローム / 動脈硬化 / 脂肪酸伸長酵素 / 炎症 / 中性脂肪 / 肥満 / 糖代謝 / エネルギー代謝 / 非アルコール性脂肪肝 / SREBP-1 / マクロファージ / 慢性炎症 / CREBH / ミトコンドリア / 食欲 / グリコーゲン / 転写調節 / インスリン感受性 / 脂質異常症 / 肝臓 / 脳 / マイオカイン / 遺伝子組み換えマウス / 分泌 / 運動 / HMGCR / 脂肪毒性 / プロテアーゼ / テネイシンC / 細胞外マトリックス / インテグリン / カロリー制限 / トリグリセリド / 細胞周期 / p21 / p27 / 脂肪 / 栄養代謝 / PKC / インスリン / 糖尿病性腎症 / シグナル伝達 / 高血糖 / ノックアウトマウス / 筋肥大 / 蛋白代謝 / トランスジェニックマウス / アデノウイルス / 精神神経疾患 / インスリン分泌 / 膵β細胞 / 嗜好性 / 食嗜好性 / 筋収縮 / 遺伝子組み換えショウジョウバエ / 内分泌学 / 健康科学 / 分子生物学 / 構成性分泌 / 調節性分泌 / 筋サテライト細胞 / インスリンシグナル / IRS-2 / insulin resistance / Metabolic Syndrome / Lifestyle-related diseases / diabetes / transcription factors / insulin signaling / IR52 / スタチン / 横紋筋融解症 / オートファジー / コレステロール合成系 / コレステロール合成 / 高次脳機能 / 脳・神経 / FGF21 / 食餌誘導性肥満 / 動脈硬化病態形成 / 泡沫化 / ABCA1 / ABCG1 / scRNA-seq / 膵ラ氏島 / 線維化 / 異質 / 膵臓ラ氏島 / NASH / 未病 / １細胞解析 / ChREBP / Elovl6 / 発現制御 / 筋線維タイプ / サルコペニア / 肥満症 / 脂肪組織 / ミトコンドリア生合成 / ミトファジー / PARIS / リソソーム / ミトコンドリアシグナルペプチダーゼ / 体内時計 / スプライシング / 脂肪細胞 / 脂肪肝 / 肝炎 / lncRNA / エクソソーム / non-coding RNA / マイクロRNA / 代謝産物 / 多価不飽和脂肪酸 / 小胞体 / オルガネラ / リピドミクス / 酵素 / ライブセルイメージング / オルガネラリピッドコード / スプライシング制御 / Mipep / リポディストロフィー / MIPEP / リポジストロフィー / protease / lipid-sensing / SOCS3 / granulopoiesis / high fat diet / inflammation / 高脂肪 / 顆粒球造血 / 肝がん / 細胞間相互作用 / 細胞接着 / テネイシン-C / マクロファージ機能調節 / 細胞接着環境 / 血管平滑筋細胞 / 循環器・高血圧 / 免疫学 / 薬理学 / 細胞・組織 / 神経分化 / HMGCoA還元酵素 / 脳形成 / ニューロン / アストロサイト / 神経新生 / コレステロール代謝 Less

The mechanism of systemic nutrient metabolism through the maintenance of small intestinal structure and intestinal environment by the interaction of small intestinal constituent cellsPrincipal Investigator
- Principal Investigator
  
  中川嘉
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Toyama
Elucidation of the mechanism of liver cancer induced by abnormal lipid metabolism in enterohepatic associationPrincipal Investigator
- Principal Investigator
  
  中川嘉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Toyama
Reguratory mechanisms of lifespan by altered energy metabolism via splicing control
- Principal Investigator
  
  樋上賀一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo University of Science
Determination of physiological significance of cholesterol synthesis system in brain formation and its application to pathological conditions
- Principal Investigator
  
  Shimano Hitoshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
Elucidation of the molecular mechanism of lipid-sensing by the novel SREBP-1 protease R4
- Principal Investigator
  
  Han Song-iee
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
SOCS3が制御する高脂肪誘発性myeloid hematopoiesisの機序
- Principal Investigator
  
  牛木隆志
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Niigata University
The study of intra-hepatic cell interation in the development of nonalcoholic fatty liver disease
- Principal Investigator
  
  Iwasaki Hitoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
The effects of SREBP-1a on intestine homeostasis are determined using intestine- or macrophage- specific SREBP-1a KO micePrincipal Investigator
- Principal Investigator
  
  Nakagawa Yoshimi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Toyama
  University of Tsukuba
運動の恩恵効果が骨格筋から分泌されるマイオカインによって媒介されることの証明
- Principal Investigator
  
  藤井宣晴
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tokyo Metropolitan University
Lifestyle-related pathological conditions by the changes in the quantity and quality of blood exosome lipids
- Principal Investigator
  
  Iwasaki Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  University of Tsukuba
Molecular mechanism of organella homeostasis regulated by quantity and quality of lipids
- Principal Investigator
  
  SHIMANO HITOSHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
Mechanism and prevention strategy of inflammation and fibrosis caused by quantitative and qualitative transformation of organ lipids in inflammation cellular society
- Principal Investigator
  
  Hitoshi Shimano
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  University of Tsukuba
Dysregulation of lysosome/mitochondrial interaction in obese adipose tissue
- Principal Investigator
  
  Higami Yoshikazu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo University of Science
Progression of atherosclerosis by enhanced macrophage foam cell formation by matricryptic site of tenascin-C
- Principal Investigator
  
  Iyoda Takuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tokyo University of Science, Yamaguchi
  Tokyo University of Science
Analysis of metabolic diseases targeting nutrient complex associated inflammation caused from enterohepatic circulationPrincipal Investigator
- Principal Investigator
  
  Nakagawa Yoshimi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Analysis of SREBP-1 activation and lipid metabolism by novel protease
- Principal Investigator
  
  Han Song-Iee
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Identification of a novel factor involved in lifestyle-related disease amelioration by the transcription factor CREB3L3
- Principal Investigator
  
  Iwasaki Hitoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Molecular mechanism of autophagic abnormality in mouse model with rhabdomyolysis
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
The molecular mechanism of organ metabolic disease state and abnormal brain function caused by Elovl6-mediated qualitative changes of fatty acids
- Principal Investigator
  
  Shimano Hitoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Macrophage Foam Cell Formation Induced by the Peptide Derived from Tenascin-C
- Principal Investigator
  
  IYODA Takuya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo University of Science
Myokines and their physiological roles
- Principal Investigator
  
  Fujii Nobuharu L
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Sports science
- Research Institution
  Tokyo Metropolitan University
The roles of CREBH in non-alcoholic fatty liver
- Principal Investigator
  
  KOBAYASHI Kazuto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  University of Tsukuba
Why did lack of cholesterol in the skeletal muscle cause rhabdomyolysis and sudden death?Principal Investigator
- Principal Investigator
  
  Nakagawa Yoshimi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Fasting-induced transcription factor CREBH ameliorates obesity via entero-hepatic circulationPrincipal Investigator
- Principal Investigator
  
  Nakagawa Yoshimi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Study for tissue specific change of lipid quality and metabolism by fatty acid elongase Elovl6
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
What are the differences between statin and the shortage of cellular cholesterol content in the pathology of rhabdomyolysis ?Principal Investigator
- Principal Investigator
  
  NAKAGAWA Yoshimi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
肝臓と食欲をつなぐ肝臓特異的発現転写因子ＣＲＥＢＨと分泌ホルモンＦＧＦ２１Principal Investigator
- Principal Investigator
  
  中川嘉
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Role of fatty acid elongase Elovl6 in the sucrose preference formation
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
The molecular mechanism that CREBH activation by nutrition improves metabolic syndromePrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yoshimi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
肝臓の脂肪酸組成変化による新規血清LDLコレステロール制御機構の解明
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Control of energy metabolism by changes of the organ lipid quality through fatty acid elongase Elovl6.
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
The role of TFE3, a metabolism-related transcription factor, in skeletal muscles.
- Principal Investigator
  
  IIDA Kaoruko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Ochanomizu University
  University of Tsukuba
脂質合成系調節転写因子SREBP-1/2の標的配列特異性を決定する共因子の解明
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
The autoloop pathogenic mechanism of diabetic complication by SREBP-1c
- Principal Investigator
  
  KOBAYASHI Kazuto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Analysis of the pleiotropic effects of TFE3 on metabolic syndrome
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
機能性RNAによる生活習慣病発症の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  中川嘉
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  基礎ゲノム科学
- Research Institution
  University of Tsukuba
The functional analysis of TFE3 to the new therapy for metabolic syndromePrincipal Investigator
- Principal Investigator
  
  NAKAGAWA Yoshimi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
脂質合成転写因子の細胞増殖、細胞周期にもたらす影響に関する検討
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Study on a novel energy metabolism transcription factor that regulates insulin signaling
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
新規エネルギー代謝関連転写因子TFE3による糖尿病治療法の確立Principal Investigator
- Principal Investigator
  
  中川嘉
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
遺伝子改変マウスを用いた新規脂肪酸組成調節酵素のエネルギー代謝に及ぼす影響の検討
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba

[Book] FGF21と糖代謝 Annual Review 糖尿病・代謝・内分泌20132013
- Author(s)
  中川嘉、菊池琢哉、島野仁
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22300234
[Book] 絶食時の肝における遺伝子発現応答 (第1土曜特集エネルギー代謝転写因子ネットワークと生活習慣病) -- (臓器・疾患別にみた転写因子の展開)The hepatic homeostasis by transcription factors in fasted condition 医学のあゆみ237(6)2011
- Author(s)
  中川嘉、島野仁
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] CREBH regulation of lipid metabolism through multifaceted functions that improve arteriosclerosis2022
- Author(s)
  Nakagawa Y, Matsuzaka T, Shimano H.
- Journal Title
  
  J Diabetes Investig .
  
  Volume: Feb 5.
- DOI
  10.1111/jdi.13766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21H03371
[Journal Article] A Novel Method of CD31-Combined ABO Carbohydrate Antigen Microarray Predicts Acute Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation2022
- Author(s)
  Tasaki M, Tateno H, Sato T, Tomioka A, Kaji H, Narimatsu H, Saito K, Nakagawa Y, Aoki T, Kamimura M, Ushiki T, Okada M, Miwa Y, Hotta K, Yoshida Y, Takahashi K, Tomita Y
- Journal Title
  
  Transplantation International
  
  Volume: 35 Pages: 10248-10248
- DOI
  10.3389/ti.2022.10248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11716, KAKENHI-PROJECT-20K09573
[Journal Article] Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice.2022
- Author(s)
  Okajima Yuka、Matsuzaka Takashi、Miyazaki Shun、Motomura Kaori、Ohno Hiroshi、Sharma Rahul、Shimura Takuya、Istiqamah Nurani、Han Song-iee、Mizunoe Yuhei、Osaki Yoshinori、Iwasaki Hitoshi、Yatoh Shigeru、Suzuki Hiroaki、Sone Hirohito、Miyamoto Takafumi、Aita Yuichi、Takeuchi Yoshinori、Sekiya Motohiro、Shimano Hitoshi
- Journal Title
  
  Biochim Biophys Acta Mol Basis Dis .
  
  Volume: 1868 Pages: 166339-166339
- DOI
  10.1016/j.bbadis.2022.166339
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition.2021
- Author(s)
  Nakagawa Yoshimi、Wang Yunong、Han Song-iee、Okuda Kanako、Oishi Asayo、Yagishita Yuka、Kumagai Kae、Ohno Hiroshi、Osaki Yoshinori、Mizunoe Yuhei、Araki Masaya、Murayama Yuki、Iwasaki Hitoshi、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Sone Hirohito、Yamada Nobuhiro、Shimano Hitoshi
- Journal Title
  
  Cell Mol Gastroenterol Hepatol .
  
  Volume: 11 Pages: 949-971
- DOI
  10.1016/j.jcmgh.2020.11.004
- NAID
  120006939158
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K11737, KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-20K21643, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-20K17505, KAKENHI-PROJECT-18KT0065, KAKENHI-PROJECT-21H04861
[Journal Article] Altered microbiota by a high-fat diet accelerates lethal myeloid hematopoiesis associated with systemic SOCS3 deficiency.2021
- Author(s)
  Cho Kaori、Ushiki Takashi、Ishiguro Hajime、Tamura Suguru、Araki Masaya、Suwabe Tatsuya、Katagiri Takayuki、Watanabe Mari、Fujimoto Yoko、Ohashi Riuko、Ajioka Yoichi、Shimizu Ippei、Okuda Shujiro、Masuko Masayoshi、Nakagawa Yoshimi、Hirai Hideyo、Alexander Warren S.、Shimano Hitoshi、Sone Hirohito
- Journal Title
  
  iScience.
  
  Volume: 24 Pages: 103117-103117
- DOI
  10.1016/j.isci.2021.103117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08354, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045, KAKENHI-PROJECT-19K11716
[Journal Article] Starvation-induced transcription factor CREBH negatively governs body growth by controlling GH signaling.2021
- Author(s)
  Nakagawa Yoshimi、Kumagai Kae、Han Song‐iee、Mizunoe Yuhei、Araki Masaya、Mizuno Seiya、Ohno Hiroshi、Matsuo Kazuya、Yamada Yasunari、Kim Jun‐dal、Miyamoto Takafumi、Sekiya Motohiro、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Takahashi Satoru、Sone Hirohito、Shimano Hitoshi
- Journal Title
  
  FASEB J
  
  Volume: 35 Pages: 21663-21663
- DOI
  10.1096/fj.202002784rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05429, KAKENHI-PROJECT-19K07095, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045, KAKENHI-PROJECT-21K19064
[Journal Article] CREBH Systemically Regulates Lipid Metabolism by Modulating and Integrating Cellular Functions.2021
- Author(s)
  Nakagawa Yoshimi、Araki Masaya、Han Song-iee、Mizunoe Yuhei、Shimano Hitoshi
- Journal Title
  
  Nutrients .
  
  Volume: 13 Pages: 3204-3204
- DOI
  10.3390/nu13093204
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045
[Journal Article] CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF2.2021
- Author(s)
  Kainoh Kenta、Takano Ryo、Sekiya Motohiro、Saito Kenji、Sugasawa Takehito、Ma Yang、Murayama Yuki、Sugano Yoko、Osaki Yoshinori、Iwasaki Hitoshi、Takeuchi Yoshinori、Yahagi Naoya、Suzuki Hiroaki、Miyamoto Takafumi、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 562 Pages: 146-153
- DOI
  10.1016/j.bbrc.2021.05.069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K17505, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] Elucidation of Molecular Mechanism of a Selective PPARα Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Principle Calculations.2020
- Author(s)
  Kawasaki Mayu、Kambe Akira、Yamamoto Yuta、Arulmozhiraja Sundaram、Ito Sohei、Nakagawa Yoshimi、Tokiwa Hiroaki、Nakano Shogo、Shimano Hitoshi
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Pages: 361-361
- DOI
  10.3390/ijms21010361
- NAID
  120007132701
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18K14391
[Journal Article] Srebp-1c/Fgf21/Pgc-1α Axis Regulated by Leptin Signaling in Adipocytes?Possible Mechanism of Caloric Restriction-Associated Metabolic Remodeling of White Adipose Tissue2020
- Author(s)
  Kobayashi Masaki、Uta Seira、Otsubo Minami、Deguchi Yusuke、Tagawa Ryoma、Mizunoe Yuhei、Nakagawa Yoshimi、Shimano Hitoshi、Higami Yoshikazu
- Journal Title
  
  Nutrients
  
  Volume: 12 Pages: 2054-2054
- DOI
  10.3390/nu12072054
- NAID
  120007147861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21611, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051
[Journal Article] Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1.2020
- Author(s)
  Ma Yang、Sekiya Motohiro、Kainoh Kenta、Matsuda Takaaki、Iwasaki Hitoshi、Osaki Yoshinori、Sugano Yoko、Suzuki Hiroaki、Takeuchi Yoshinori、Miyamoto Takafumi、Yahagi Naoya、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 523 Pages: 354-360
- DOI
  10.1016/j.bbrc.2019.12.070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-18K06206
[Journal Article] CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms2020
- Author(s)
  Satoh A, Han S, Araki M, Nakagawa Y, Ohno H, Mizunoe Y, Kumagai K, Murayama Y, Osaki Y, Iwasaki H, Sekiya M, Konishi M, Itoh N, Matsuzaka T, Sone H, and Shimano H.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 3 Pages: 100930-100930
- DOI
  10.1016/j.isci.2020.100930
- NAID
  120006891020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07095, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-19H00449, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K11737, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18KT0065
[Journal Article] Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes.2020
- Author(s)
  Mizunoe Yuhei、Kobayashi Masaki、Hoshino Shunsuke、Tagawa Ryoma、Itagawa Rei、Hoshino Ayana、Okita Naoyuki、Sudo Yuka、Nakagawa Yoshimi、Shimano Hitoshi、Higami Yoshikazu
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Pages: 634-634
- DOI
  10.1038/s41598-020-57428-6
- NAID
  120007165462
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11119, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-18K17953, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051
[Journal Article] Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice2020
- Author(s)
  Matsuzaka T, Kuba M, Koyasu S, Takeuchi Y, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Ema M, Takahashi S, Tokiwa H, Shimano H.
- Journal Title
  
  Hepatology
  
  Volume: 71 Pages: 1609-1625
- DOI
  10.1002/hep.30953
- NAID
  120007132717
- Description
  in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20175, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K21611, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18K06206
[Journal Article] Severity of hypertension as a predictor of initiation of dialysis among study participants with and without diabetes mellitus2020
- Author(s)
  Osawa Taeko、Fujihara Kazuya、Harada Yamada Mayuko、Yamamoto Masahiko、Kitazawa Masaru、Matsubayashi Yasuhiro、Iwanaga Midori、Yamada Takaho、Seida Hiroyasu、Kodama Satoru、Nakagawa Yoshimi、Shimano Hitoshi、Sone Hirohito
- Journal Title
  
  Journal of Investigative Medicine
  
  Volume: 69 Pages: 724-729
- DOI
  10.1136/jim-2020-001489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-18H04051
[Journal Article] Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex.2019
- Author(s)
  Murayama Yuki, Takafumi Miyamoto, et al.
- Journal Title
  
  FEBS Lett
  
  Volume: 593 Pages: 423-432
- DOI
  10.1002/1873-3468.13328
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17K12895, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-17K00846
[Journal Article] Exercise training reduces ventricular arrhythmias through restoring calcium handling and sympathetic tone in myocardial infarction mice2019
- Author(s)
  Qin Rujie、Murakoshi Nobuyuki、Xu DongZhu、Tajiri Kazuko、Feng Duo、Stujanna Endin N.、Yonebayashi Saori、Nakagawa Yoshimi、Shimano Hitoshi、Nogami Akihiko、Koike Akira、Aonuma Kazutaka、Ieda Masaki
- Journal Title
  
  Physiological Reports
  
  Volume: 7
- DOI
  10.14814/phy2.13972
- NAID
  120007133480
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K09567
[Journal Article] Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism.2019
- Author(s)
  Sharma Rahu, Takafumi Miyamoto, et al.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Pages: 1-12
- DOI
  10.1038/s41598-019-41631-1
- NAID
  120007133465
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PROJECT-18K19724, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17H05060
[Journal Article] Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome.2019
- Author(s)
  Mizunoe Yuhei、Kobayashi Masaki、Tagawa Ryoma、Nakagawa Yoshimi、Shimano Hitoshi、Higami Yoshikazu
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Pages: 3688-3688
- DOI
  10.3390/ijms20153688
- NAID
  120007133171
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-18K17953, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051
[Journal Article] Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood.2018
- Author(s)
  X Yuan, K Tsujimoto, K Hashimoto, K Kawahori, N Hanzawa, M Hamaguchi, T Seki, M Nawa, T Ehara, Y Kitamura, I Hatada, M Konishi, N Itoh, Y Nakagawa, H Shimano, T Takai-Igarashi, Y Kamei, Y Ogawa.
- Journal Title
  
  Nat. Commun.
  
  Volume: 9 Pages: 636-636
- DOI
  10.1038/s41467-018-03038-w
- NAID
  120007134467
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00295, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K01840, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16H05331, KAKENHI-PROJECT-18K11420, KAKENHI-PROJECT-18K18461, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-16H04926, KAKENHI-PROJECT-17H06652
[Journal Article] The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice.2018
- Author(s)
  Araki Masaya、Nakagawa Yoshimi、Oishi Asayo、Han Song-iee、Wang Yunong、Kumagai Kae、Ohno Hiroshi、Mizunoe Yuhei、Iwasaki Hitoshi、Sekiya Motohiro、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 19 Pages: 2148-2148
- DOI
  10.3390/ijms19072148
- NAID
  120007133834
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811
[Journal Article] 14. Critical role of CREBH-mediated induction of transforming growth factor β2 by hepatitis C virus infection in fibrogenic responses in hepatic stellate cells.2018
- Author(s)
  Chida Takeshi、Ito Masahiko、Nakashima Kenji、Kanegae Yumi、Aoshima Takuya、Takabayashi Shuji、Kawata Kazuhito、Nakagawa Yoshimi、Yamamoto Masahiro、Shimano Hitoshi、Matsuura Tomokazu、Kobayashi Yoshimasa、Suda Takafumi、Suzuki Tetsuro
- Journal Title
  
  Hepatology.
  
  Volume: 66 Pages: 1430-1443
- DOI
  10.1002/hep.29319
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K19137, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H04735, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-15K09214
[Journal Article] CREBH Regulates Systemic Glucose and Lipid Metabolism.2018
- Author(s)
  Nakagawa Yoshimi、Shimano Hitoshi
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Pages: 1396-1396
- DOI
  10.3390/ijms19051396
- NAID
  120007133987
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16K01811
[Journal Article] Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance2018
- Author(s)
  Ohno H, Matsuzaka T, Tang N, Sharma R, Motomura K, Shimura T, Satoh A, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Nakagawa Y, Sone H, Yahagi N, Yamada N, Higami Y, Shimano H.
- Journal Title
  
  Endocrinology
  
  Volume: 159(6) Pages: 2308-2323
- DOI
  10.1210/en.2017-03179
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17H05060
[Journal Article] Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood.2018
- Author(s)
  Yuan X, Tsujimoto K, Hashimoto K, Kawahori K, Hanzawa N, Hamaguchi M, Seki T, Nawa M, Ehara T, Kitamura Y, Hatada I, Konishi M, Itoh N, Nakagawa Y, Shimano H, Takai-Igarashi T, Kamei Y, Ogawa Y.
- Journal Title
  
  Nat Commun.
  
  Volume: 9(1) Pages: 636-636
- NAID
  120007134467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06395
[Journal Article] Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα.2018
- Author(s)
  Yamamoto Yuta、Takei Kenta、Arulmozhiraja Sundaram、Sladek Vladimir、Matsuo Naoya、Han Song-iee、Matsuzaka Takashi、Sekiya Motohiro、Tokiwa Takaki、Shoji Mitsuo、Shigeta Yasuteru、Nakagawa Yoshimi、Tokiwa Hiroaki、Shimano Hitoshi
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 499 Pages: 239-245
- DOI
  10.1016/j.bbrc.2018.03.135
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0010, KAKENHI-PROJECT-16H03253, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16K01811
[Journal Article] A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes2018
- Author(s)
  Piao X, Yahagi N, Takeuchi Y, Aita Y, Murayama Y, Sawada Y, Shikama A, Masuda Y, Nishi-Tatsumi M, Kubota M, Izumida Y, Sekiya M, Matsuzaka T, Nakagawa Y, Sugano Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Shimano H.
- Journal Title
  
  FEBS Letters
  
  Volume: 592(3) Pages: 422-433
- DOI
  10.1002/1873-3468.12975
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H05060
[Journal Article] Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.2017
- Author(s)
  Zhao Hui、Matsuzaka Takashi、Nakano Yuta、Motomura Kaori、Tang Nie、Yokoo Tomotaka、Okajima Yuka、Han Song-iee、Takeuchi Yoshinori、Aita Yuichi、Iwasaki Hitoshi、Yatoh Shigeru、Suzuki Hiroaki、Sekiya Motohiro、Yahagi Naoya、Nakagawa Yoshimi、Sone Hirohito、Yamada Nobuhiro、Shimano Hitoshi
- Journal Title
  
  Diabetes.
  
  Volume: 66 Pages: 1833-1846
- DOI
  10.2337/db16-1277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K09738, KAKENHI-PROJECT-17K13217, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-17H05060
[Journal Article] Mitochondrial intermediate peptidase is a novel regulator of sirtuin-3 activation by caloric restriction.2017
- Author(s)
  Kobayashi Masaki、Takeda Kanae、Narita Takumi、Nagai Keita、Okita Naoyuki、Sudo Yuka、Miura Yuri、Tsumoto Hiroki、Nakagawa Yoshimi、Shimano Hitoshi、Higami Yoshikazu
- Journal Title
  
  FEBS Lett
  
  Volume: 591 Pages: 4067-4073
- DOI
  10.1002/1873-3468.12914
- NAID
  120007134579
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-17K13231, KAKENHI-PROJECT-17H02179
[Journal Article] Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry.2017
- Author(s)
  Nishi-Tatsumi M, Yahagi N, Takeuchi Y, Toya N, Takarada A, Murayama Y, Aita Y, Sawada Y, Piao X, Oya Y, Shikama A, Masuda Y, Kubota M, Izumida Y, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Kawakami Y, Kadowaki T, Yamada N, Shimano H.
- Journal Title
  
  FEBS Letters
  
  Volume: 591 Pages: 40-45
- DOI
  10.1002/1873-3468.12620
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-17H05060
[Journal Article] The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice.2017
- Author(s)
  Takei K, Han SI, Murayama Y, Satoh A, Oikawa F, Ohno H, Osaki Y, Matsuzaka T, Sekiya M, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Yamada N, Nakagawa Y, Shimano H.
- Journal Title
  
  J Diabetes Investig
  
  Volume: in press Pages: 446-452
- DOI
  10.1111/jdi.12621
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K09738, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040
[Journal Article] Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry.2017
- Author(s)
  Sawada Yoshikazu、Izumida Yoshihiko、Takeuchi Yoshinori、Aita Yuichi、Wada Nobuhiro、Li EnXu、Murayama Yuki、Piao Xianying、Shikama Akito、Masuda Yukari、Nishi-Tatsumi Makiko、Kubota Midori、Sekiya Motohiro、Matsuzaka Takashi、Nakagawa Yoshimi、Shimano Hitoshi、Yahagi Naoya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 493 Pages: 40-45
- DOI
  10.1016/j.bbrc.2017.09.081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-17H05060
[Journal Article] Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice.2017
- Author(s)
  Takei K, Nakagawa Y, Wang Y, Han SI, Satoh A, Sekiya M, Matsuzaka T, Shimano H.
- Journal Title
  
  Pharmacol Sci.
  
  Volume: 印刷中 Pages: 214-222
- DOI
  10.1016/j.jphs.2017.02.003
- NAID
  120007128987
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-16H03253
[Journal Article] Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.2016
- Author(s)
  Kikuchi T, Orihara K, Oikawa F, Han SI, Kuba M, Okuda K, Satoh A, Osaki Y, Takeuchi Y, Aita Y, Matsuzaka T, Iwasaki H, Yatoh S, Sekiya M, Yahagi N, Suzuki H, Sone H, Nakagawa Y, Yamada N, Shimano H.
- Journal Title
  
  Mol Metab.
  
  Volume: 5(11) Pages: 1092-1102
- NAID
  120007129266
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02541
[Journal Article] Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout micegenerated using a one-step CRISPR/Cas9 system.2016
- Author(s)
  Nakagawa Y, Oikawa F, Ohno H, Yagishita Y, Satoh A, Osaki Y, Takei K, Kikuchi T, Song-iee H, Mizuno S, Matsuzaka T, Iwasaki H, Kobayashi K, Yatoh S, Yahagi N, Suzuki H, Sone H, Takahashi S, Yamada N, Shimano H.
- Journal Title
  
  Scientific Report
  
  Volume: 6 Pages: 27857-27857
- DOI
  10.1038/srep27857
- NAID
  120007135376
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-26500001, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-16H06276
[Journal Article] Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.2016
- Author(s)
  5.Kikuchi T, Orihara K, Oikawa F, Han SI, Kuba M, Okuda K, Satoh A, Osaki Y, Takeuchi Y, Aita Y, Matsuzaka T, Iwasaki H, Yatoh S, Sekiya M, Yahagi N, Suzuki H, Sone H, Nakagawa Y, Yamada N, Shimano H.
- Journal Title
  
  Molecular Metabolism
  
  Volume: 5 Pages: 1092-1102
- NAID
  120007129266
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H03253
[Journal Article] CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARa2016
- Author(s)
  Nakagawa Y, Satoh A, Tezuka H, Han SI, Takei K, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Iwasaki Y, Sone H, Matsuzaka T, Yamada N, Shimano H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 39182-39182
- DOI
  10.1038/srep39182
- NAID
  120007135285
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-15K09436, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040
[Journal Article] Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice2016
- Author(s)
  Suzuki-Kemuriyama N, Matsuzaka T, Kuba M, Ohno H, Han SI, Takeuchi Y, Isaka M, Kobayashi K, Iwasaki H, Yatoh S, Suzuki H, Miyajima K, Nakae D, Yahagi N, Nakagawa Y, Sone H, Yamada N, Shimano H.
- Journal Title
  
  PLoS One
  
  Volume: 11(6)
- DOI
  10.1371/journal.pone.0157580
- NAID
  120007135350
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040
[Journal Article] Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.2016
- Author(s)
  Kikuchi T, Orihara K, Oikawa F, Han SI, Kuba M, Okuda K, Satoh A, Osaki Y, Takeuchi Y, Aita Y, Matsuzaka T, Iwasaki H, Yatoh S, Sekiya M, Yahagi N, Suzuki H, Sone H, Nakagawa Y, Yamada N, Shimano H.
- Journal Title
  
  Mol Metab.
  
  Volume: 5 Pages: 1092-1102
- NAID
  120007129266
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811
[Journal Article] KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.2016
- Author(s)
  Takeuchi Y, Yahagi N, Aita Y, Murayama Y, Sawada Y, Piao X, Toya N, Oya Y, Shikama A, Takarada A, Masuda Y, Nishi M, Kubota M, Izumida Y, Yamamoto T, Sekiya M, Matsuzaka T, Nakagawa Y, Urayama O, Kawakami Y, Iizuka Y, Gotoda T, Itaka K, Kataoka K, Nagai R, Kadowaki T, Yamada N, Lu Y, Jain MK, and Shimano H
- Journal Title
  
  Cell Reports
  
  Volume: 16 Pages: 2373-2386
- DOI
  10.1016/j.celrep.2016.07.069
- NAID
  120007129426
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-15H04824, KAKENHI-PROJECT-26461357, KAKENHI-PROJECT-16K13040
[Journal Article] Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice2016
- Author(s)
  Kikuchi M, Shimada M, Matsuzaka T, Ishii K, Nakagawa Y, Takayanagi M, Yamada N, Shimano H.
- Journal Title
  
  PLOS ONE
  
  Volume: 11(7)
- DOI
  10.1371/journal.pone.0159375
- NAID
  120007129433
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-26461377, KAKENHI-PROJECT-26560393
[Journal Article] Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model.2015
- Author(s)
  Kuba M, Matsuzaka T, Matsumori R, Saito R, Kaga N, Taka H, Ikehata K, Okada N,
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Pages: 1-14
- DOI
  10.1038/srep17604
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-26882008, KAKENHI-PROJECT-25430140, KAKENHI-PROJECT-26560392, KAKENHI-PROJECT-26800271, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-15H03092
[Journal Article] Identification of human ELOVL5 enhancer regions controlled by SREBP.2015
- Author(s)
  Osaki Y, Nakagawa Y, Miyahara S, Iwasaki H, Ishii A, Matsuzaka T, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Suzuki H, Sone H, Ohashi K, Ishibashi S, Yamada N, Shimano H
- Journal Title
  
  Biochemical and Biophysical Research Communications.
  
  Volume: 466(3) Pages: 536-40
- DOI
  10.1016/j.bbrc.2015.09.065
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15344, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-13J00607, KAKENHI-PROJECT-26560391, KAKENHI-PROJECT-26560392, KAKENHI-PROJECT-25293213, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-15H03092
[Journal Article] Identification of human ELOVL5 enhancer regions controlled by SREBP.2015
- Author(s)
  Shikama A, Shinozaki H, Takeuchi Y, Matsuzaka T, Aita Y, Murayama T, Sawada Y, Piao X, Toya N, Oya Y, Takarada A, Masuda Y, Nishi M, Kubota M, Izumida Y, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Yamada N, Shimano H, Yahagi N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 465(4) Pages: 857-63
- DOI
  10.1016/j.bbrc.2015.08.101
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-25461332, KAKENHI-PROJECT-26560392, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-15H03092
[Journal Article] Ligand-activated PPARα-dependent DNA demethylation regulates the fatty acid β-oxidation genes in the postnatal liver2015
- Author(s)
  Ehara T, Kamei Y, Yuan X, Takahashi M, Kanai S, Tamura E, Tsujimoto K, Tamiya T, Nakagawa Y, Shimano H, Takai-Igarashi T, Hatada I, Suganami T, Hashimoto K, Ogawa Y.
- Journal Title
  
  Diabetes
  
  Volume: 64(3) Pages: 775-784
- DOI
  10.2337/db14-0158
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390230, KAKENHI-PUBLICLY-25126701, KAKENHI-PUBLICLY-25126723, KAKENHI-PROJECT-26670448, KAKENHI-PROJECT-26350884, KAKENHI-PROJECT-15K12669, KAKENHI-PROJECT-25292076
[Journal Article] Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes. Endocrinology.2014
- Author(s)
  Yoshimi Nakagawa,* Aoi Satoh,* Sachiko Yabe,* Mika Furusawa, Naoko Tokushige, Hitomi Tezuka, Motoki Mikami, Wakiko Iwata, Akiko Shingyouchi, Takashi Matsuzaka, Shiori Kiwata, Yuri Fujimoto, Yasushi Kawakami, Osamu Urayama, Nobuhiro Yamada, and Hitoshi Shimano et. al
- Journal Title
  
  Endocrinology.
  
  Volume: 155(12) Pages: 4706-19
- DOI
  10.1210/en.2014-1113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J00094, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25282214, KAKENHI-PROJECT-25670430, KAKENHI-PROJECT-26670448, KAKENHI-PLANNED-23116006
[Journal Article] Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice.2014
- Author(s)
  Han SI, Komatsu Y, Murayama A, Steffensen KR, Nakagawa Y, Nakajima Y, Suzuki M, Oie S, Parini P, Vedin LL, Kishimoto H, Shimano H, Gustafsson JÅ, Yanagisawa J.
- Journal Title
  
  Hepatology.
  
  Volume: 59(5) Pages: 1791-1802
- DOI
  10.1002/hep.26951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40085, KAKENHI-PROJECT-24390230, KAKENHI-PUBLICLY-25126701
[Journal Article] Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion.2014
- Author(s)
  Tang N, Matsuzaka T, Suzuki M, Nakano Y, Zao H, Yokoo T, Suzuki-Kemuriyama N, Kuba M, Okajima Y, Takeuchi Y, Kobayashi K, Iwasaki H, Yatoh S, Takahashi A, Suzuki H, Sone H, Shimada M, Nakagawa Y, Yahagi N, Yamada N, Shimano H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 450(1) Pages: 318-23
- DOI
  10.1016/j.bbrc.2014.05.113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25670430, KAKENHI-PROJECT-26670448, KAKENHI-PLANNED-23116006
[Journal Article] TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.2013
- Author(s)
  Naka A, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 430 Pages: 664-669
- DOI
  10.1016/j.bbrc.2012.11.094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-10J01029, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23659473, KAKENHI-PROJECT-24300233, KAKENHI-PROJECT-24300254, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659440, KAKENHI-PROJECT-24659441
[Journal Article] Elovl6 promotes nonalcoholic steatohepatitis in mice and humans.2013
- Author(s)
  Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A, Takekoshi K, Sone H, Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H.
- Journal Title
  
  Hepatology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.2013
- Author(s)
  Naka A, Iida K, Nakagawa Y, Iwasaki H, Takeuchi Y, Satoh A, Matsuzaka T, Ishii KA, Kobayashi K, Yatoh S, Shimada M, Yahagi N, Suzuki H, Sone H, Yamada N, Shimano H.
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  Biochem Biophys Res Commun.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization2013
- Author(s)
  Izumida Y, Yahagi N, Takeuchi Y, Nishi M, Shikama A, Takarada A, Masuda Y, Kubota M, Matsuzaka T, Nakagawa Y, Iizuka Y, Itaka K, Kataoka K, Shioda S, Niijima A, Yamada T, Katagiri H, Nagai R, Yamada N, Kadowaki T, Shimano H
- Journal Title
  
  Nature Communications
  
  Volume: 4 Pages: 2316-2316
- DOI
  10.1038/ncomms3316
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22126004, KAKENHI-PLANNED-22126006, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23591293, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659439, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461332, KAKENHI-PROJECT-25670430
[Journal Article] TFE3 inhibits myoblast differentiation inC2C12 cells via down-regulating geneexpression of myogenin2013
- Author(s)
  Naka A, Iida KT, Nakagawa Y, IwasakiH, Takeuchi Y, Satoh A, Matsuzaka T, IshiiKA, Kobayashi K, Yatoh S, Shimada M, YahagiN, Suzuki H, Sone H, Yamada N, Shimano H
- Journal Title
  
  Biochem BiophysRes Commun
  
  Volume: 430(2) Pages: 664-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] regulates muscle metabolic geneexpression, increases glycogen stores,and enhances insulin sensitivity in mice.2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, NakagawaY, Matsuzaka T, Ishii KA, Kobayashi K,Takahashi A, Yatoh S, Yahagi N, Sone H,Suzuki H, Yamada N, Shimano H
- Volume
  302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] Dicer hasa crucial role in the early stage ofadipocyte differentiation, but not inlipid synthesis, in 3T3-L1 cells2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Shingyouchi A,Tokushige N, Nakanishi N, Satoh A,Matsuzaka T, Ishii KA, Iwasaki H,Kobayashi K, Yatoh S, Suzuki H, Yahagi N,Urayama O, Yamada N, Shimano H
- Journal Title
  
  BiochemBiophys Res Commun
  
  Volume: 420(4) Pages: 931-936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] Elovl6 promotes nonalcoholic steatohepatitis2012
- Author(s)
  Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A,Takekoshi K, Sone H, Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H
- Journal Title
  
  Hepatology
  
  Volume: 56(6) Pages: 2199-2208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] TFE3 Regulates Muscle Metabolic Gene Expression, Increases Glycogen Stores, and Enhances Insulin Sensitivity in Mice2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500677
[Journal Article] TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances in sulin sensitivity in mice2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Elovl6 promotes nonalcoholic steatohepatitis.2012
- Author(s)
  Takashi Matsuzaka, et al
- Journal Title
  
  Hepatology.
  
  Volume: 56 Pages: 2199-208
- DOI
  10.1002/hep.25932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00911, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23659464, KAKENHI-PROJECT-23659473, KAKENHI-PROJECT-23791480, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659441, KAKENHI-PROJECT-24680072
[Journal Article] Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T8-L1 cells.2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Shingyouchi A, Tokushige N, Nakanishi N, Satoh A, Matsuzaka T, Ishii KA, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yahagi N, Urayama O, Yamada N, Shimano H
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  Biochem Biophys Res Commun.
  
  Volume: 420 Pages: 931-6
- DOI
  10.1016/j.bbrc.2012.03.110
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659441
[Journal Article] Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells.2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Shingyouchi A, Tokushige N, Nakanishi N, Satoh A, Matsuzaka T, Ishii KA, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yahagi N, Urayama O, Yamada N, Shimano H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 420(4) Pages: 931-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] TFE3 Regulates Muscle Metabolic Gene Expression, Increases Glycogen Stores, and Enhances Insulin Sensitivity in Mice.2012
- Author(s)
  Iwasaki H, Naka A, Iida K, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 302(7)
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- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.2011
- Author(s)
  Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N, Shimano H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice.2011
- Author(s)
  Karasawa T, Takahashi A, Saito R, Sekiya M, Igarashi M, Iwasaki H, Miyahara S, Koyasu S, Nakagawa Y, Ishii K, Matsuzaka T, Kobayashi K, Yahagi N, Takekoshi K, Sone H, Yatoh S, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoprotein sand accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Karasawa T, Takahashi A, Saito R, Sekiya M, Igarashi M, Iwasaki H, Miyahara S, Koyasu S, Nakagawa Y, Ishii K, Matsuzaka T, Kobayashi K, Yahagi N, Takekoshi K, Sone H, Yatoh S, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Macrophage Elovl6deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N, Shimano H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hep atosteatosis through Kruppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice2011
- Author(s)
  Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H
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  J Biol Chem
  
  Volume: 286(47) Pages: 40835-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Kruppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.2011
- Author(s)
  Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H.
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  J Biol Chem.
  
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- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol regulatory element binding protein-lc by insulin.2010
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  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
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  J Lipid Res.
  
  Volume: 51 Pages: 1859-1870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res.
  
  Volume: 51 Pages: 1859-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659173
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 11681-11691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol regulatory element-binding protein-1c by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res.
  
  Volume: 51(7) Pages: 1859-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 11681-11691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.2010
- Author(s)
  Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 391
  
  Pages: 1222-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(15) Pages: 11681-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H
- Journal Title
  
  J Biol Chem. 285(15)
  
  Pages: 11681-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol regulatory element-binding protein-1c by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H
- Journal Title
  
  J Lipid Res. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha2010
- Author(s)
  Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 391
  
  Pages: 1222-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.2010
- Author(s)
  Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 391(2) Pages: 1222-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol regulatory element-binding protein-1c by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H
- Journal Title
  
  J Lipid Res. 51(7)
  
  Pages: 1859-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591043
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, TeraokaY, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 11681-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659173
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 11681-11691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Adipocyte-Derived Microvesicles Are Associated with Multiple Angiogenic Factors and Induce Angiogenesis in Vivo and in Vitro.2010
- Author(s)
  Aoki N, Yokoyama R, Asai N, Ohki M, Ohki Y, Kusubata K, Heissig B, Hattori K, Nakagawa Y, Matsuda T
- Journal Title
  
  Endocrinology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN2009
- Author(s)
  Kato M, Putta S, Wang M, Yuan H, Lanting L, Nair I, Gunn A, Nakagawa Y, Shimano H, Todorov I, Rossi JJ, Natarajan R
- Journal Title
  
  Nat Cell Biol 11
  
  Pages: 881-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice2009
- Author(s)
  Nakanishi N, Nakagawa Y, Tokushige N, Aoki N, Matsuzaka T, Ishii K, Yahagi N, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Urayama O, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 385
  
  Pages: 492-496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN.2009
- Author(s)
  Kato M, Putts, S, Wang M, Yuan H, Lanting L, Nair I, Gunn A, Nakagawa Y, Shimano H, Todorov I, Rossi JJ, Natarajan R
- Journal Title
  
  Nat Cell Biol 11
  
  Pages: 881-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN.2009
- Author(s)
  Kato M, Putta S, Wang M, Yuan H, Lanting L, Nair I, Gunn A, Nakagawa Y, Shimano H, Todorov I, Rossi JJ, Natarajan R
- Journal Title
  
  Nature Cell Biology. 11(7)
  
  Pages: 881-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice.2009
- Author(s)
  Nakanishi N, Nakagawa Y, Tokushige N, Aoki N, Matsuzaka T, Ishii K, Yahagi N, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Urayama O, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 385
  
  Pages: 492-496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.2008
- Author(s)
  Kato T, Shimano H, Yamamoto T, Ishikawa M, Kumadaki S, Matsuzaka T, Nakagawa Y, Yahagi N, Nakakuki M, Hasty AH, Takeuchi Y, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Sone H, Yamada N
- Journal Title
  
  Diabetes 57(9)
  
  Pages: 2382-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity.2008
- Author(s)
  Ishikawa M, Iwasaki Y, Yatoh S, Kato T, Kumadaki S, Inoue N, Yamamoto T, Matsuzaka T, Nakagawa Y, Yahagi N, Kobayashi K, Takahashi A, Yamada N, Shimano H
- Journal Title
  
  J Lipid Res. 49(12)
  
  Pages: 2524-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice : a new model for lipotoxicity.2008
- Author(s)
  Ishikawa M, Iwasaki Y, Yatoh S, Kato T, Kumadaki S, Inoue N, Yamamoto T, Matsuzaka T, Nakagawa Y, Yahagi N, Kobayashi K, Takahashi A, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res. 49(12)
  
  Pages: 2524-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets2008
- Author(s)
  Kato T, Shimano H, Yamamoto T, Ishikawa M, Kumadaki S, Matsuzaka T, Nakagawa Y, Yahagi N, Nakakuki M, Hasty AH, Takeuchi Y, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Sone H, Yamada N
- Journal Title
  
  Diabetes 57(9)
  
  Pages: 2382-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance2008
- Author(s)
  Inoue N, Yahagi N, Yamamoto T, Ishikawa M, Watanabe K, Matsuzaka T, Nakagawa Y, Takeuchi Y, Kobayashi K, Takahashi A, Suzuki H, Hasty AH, Toyoshima H, Yamada N, Shimano H
- Journal Title
  
  J Biol Chem. 283(30)
  
  Pages: 21220-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.2008
- Author(s)
  Inoue N, Yahagi N, Yamamoto T, Ishikawa M, Watanabe K, Matsuzaka T, Nakagawa Y, Takeuchi Y, Kobayashi K, Takahashi A, Suzuki H, Hasty AH, Toyoshima H, Yamada N, Shimano H
- Journal Title
  
  J Biol Chem. 283(30)
  
  Pages: 21220-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] Crucial role of a long-chain fatty acid elongase, Elov16, in obesity-induced insulin resistance2007
- Author(s)
  Matsuzaka T, Shimano H, Nakagawa Y, et. al.
- Journal Title
  
  Nat Med. 13(10)
  
  Pages: 1193-1202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance2007
- Author(s)
  Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S, Ishigaki N, Iwasaki H, Iwasaki Y, Karasawa T, Kumadaki S, Matsui T, Sekiya M, Ohashi K, Hasty AH, Nakagawa Y, Takahashi A, Suzuki H, Yatoh S, Sone H, Toyoshima H, Osuga J, Yamada N.
- Journal Title
  
  Nat Med. 13(10)
  
  Pages: 1193-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] SREBP-1-independent regulation of lipogenic gene expression in adipocytes2007
- Author(s)
  Sekiya M, Yahagi N, Matsuzaka T, Takeuchi Y, Nakagawa Y, Takahashi H, Okazaki H, Iizuka Y, Ohashi K, Gotoda T, Ishibashi S, Nagai R, Yamazaki T, Kadowaki T, Yamada N, Osuga J, Shimano H.
- Journal Title
  
  J Lipid Res. 48(7)
  
  Pages: 1581-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.2007
- Author(s)
  Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S, Ishigaki N, Iwasaki H, Iwasaki Y, Karasawa T, Kumadaki S, Matsui T, Sekiya M, Ohashi K, Hasty AH, Nakagawa Y, Takahashi A, Suzuki H, Yatoh S, Sone H, Toyoshima H, Osuga J, Yamada N.
- Journal Title
  
  Nat Med. 13(10)
  
  Pages: 1193-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver.2007
- Author(s)
  Yamamoto T, Shimano H, Inoue N, Nakagawa Y, Matsuzaka T, Takahashi A, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N
- Journal Title
  
  J Biol Chem. 282(16)
  
  Pages: 11687-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19689019
[Journal Article] Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver2007
- Author(s)
  Yamamoto T, Shimano H, Inoue N, Nakagawa Y, Matsuzaka T, Takahashi A, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N.
- Journal Title
  
  J Biol Chem. 282(16)
  
  Pages: 11687-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-lc expression.2007
- Author(s)
  Takeuchi Y, Nakagawa Y, Matsuzaka T, Shimano H., et. al.
- Journal Title
  
  Biochem Biophys Res Commun. 363(2)
  
  Pages: 329-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] A transcription factor of lipid synthesis, sterol regulatory element-binding protein(SREBP)-la causes G(l) cell-cycle arrest after accumulation of cyclin-dependent kinase(cdk)inhibitors.2007
- Author(s)
  Nakakuki M, Shimano H Matsuzaka T, Nakagawa Y, et. al.
- Journal Title
  
  FEBS J. 274(17)
  
  Pages: 4440-4452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] TFE3 transcriptionally activates hepatic IRS-2, participates in insulin-signaling and, ameliorates diabetes.2006
- Author(s)
  Nakagawa Y et al.
- Journal Title
  
  Nature Med 12(1)
  
  Pages: 107-113
- Data Source
  KAKENHI-PROJECT-17390259
[Journal Article] TFE3 transcriptionally activates hepatic TRS-2, participates in insulin signaling and ameliorates diabetes.2006
- Author(s)
  Nakagawa Y
- Journal Title
  
  Nature Medicine 12(1)
  
  Pages: 107-113
- Data Source
  KAKENHI-PROJECT-16790506
[Journal Article] TFE3 transcriptionally activates hepatic IRS-2, participates in insulin-signaling and, ameliorates diabetes.2006
- Author(s)
  Nakagawa Y et al.
- Journal Title
  
  Nature Med 12(1)
  
  Pages: 107-113
- Data Source
  KAKENHI-PROJECT-17659271
[Journal Article] Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.2006
- Author(s)
  Kato T, Shimano H, Yamamoto T, Yokoo T, Endo Y, Ishikawa M, Matsuzaka T, Nakagawa Y, Kumadaki S, Yahagi N, Takahashi A, Sone H, Suzuki H, Toyoshima H, Hasty AH, Takahashi S, Gomi H, Izumi T, Yamada N.
- Journal Title
  
  Cell Metab. 4(2)
  
  Pages: 143-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390259
[Journal Article] Receptor-type protein tyrosine phosphatase epsilon (PTPepsilon M)is a negative regulator of insulin signaling in primary hepatocytes and liver.2005
- Author(s)
  Nakagawa Y
- Journal Title
  
  Zoolog Sci. 22(2)
  
  Pages: 169-175
- Data Source
  KAKENHI-PROJECT-16790506
[Journal Article] Tyrosine Phosphatase εM Stimulates Migration and Survival of Porcine Aortic Endothelial Cells by Activating c-Src2004
- Author(s)
  Y Nakagawa
- Journal Title
  
  Biochem Biophys Res Commun. 325(1)
  
  Pages: 314-319
- Data Source
  KAKENHI-PROJECT-16790506
[Journal Article] Protein Kinase A suppresses SREBP-1c expression via phosphorylation of LXR in the liver.2000
- Author(s)
  Yamamoto T, Shimano H, Inoue N, Nakagawa Y, Matsuzaka T, Takahashi A, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N.
- Journal Title
  
  J Biol Chem. (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390259
[Presentation] 筋細胞融合を制御する、de novoコレステロールの重要性2021
- Author(s)
  水之江雄平、宮本崇史、中川嘉、島野仁
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04861
[Presentation] CREB3L3 protects atherosclerosis through increased lipolysis and inhibition of SREBP2021
- Author(s)
  Masaya Araki, Yoshimi Nakagawa, Song-Iee Han, Yunoug Wang, Yuhei Mizunoe, Takashi Matsuzaka, Naoya Yahagi, Motohiro Sekiya, Hitoshi Shimano.
- Organizer
  The 19th International Symposium on Atherosclerosis (ISA2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04861
[Presentation] 動脈硬化における脂質代謝・吸収を司る転写制御メカニズム2021
- Author(s)
  中川　嘉
- Organizer
  第53回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04861
[Presentation] O-GlcNAcylation of CREBH and ChREBP synergistically control hepatic fructose-mediated nutrient metabolism2021
- Author(s)
  Yunong Wang, Yoshimi Nakagawa, Song-iee Han, Kae Kumagai, Yuhei Mizunoe, Masaya Araki, Takafumi Miyamoto, Motohiro Sekiya, Takashi Matsuzaka, Hitoshi Shimano.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04861
[Presentation] 脂肪酸伸長酵素Elovl6による神経幹細胞の自己複製能制御機構解明2021
- Author(s)
  大野博, 松坂賢, 本村香織, 志村拓哉, 水之江雄平, 宮本崇史, 関谷元博, 中川嘉, 林昭夫, 島野仁
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H04861
[Presentation] 脂肪酸の量的・質的制御と動脈硬化予防について　動脈硬化における脂質代謝・吸収を司る転写制御メカニズム2021
- Author(s)
  中川嘉、島野仁
- Organizer
  第53回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 脂肪酸伸長酵素Elovl6による神経幹細胞の自己複製能制御機構解明2021
- Author(s)
  大野博, 松坂賢, 本村香織, 志村拓哉, 水之江雄平, 宮本崇史, 関谷元博, 中川嘉, 林昭夫, 島野仁
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 栄養飢餓誘導転写因子が制御する栄養代謝メカニズムと生活習慣病改善機構2021
- Author(s)
  中川　嘉
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H04861
[Presentation] 肝・腸管・骨格筋Axisを基軸とした代謝栄養管理の実践　空腸切除による残存回腸の"空腸化"は生じるのか?　小腸切除マウスモデルを用いた解析2020
- Author(s)
  佐々木理人, 増本幸二, 小野健太郎, 堀口比奈子, 西塔翔吾, 伊藤愛香里, 根本悠里, 田中尚, 相吉翼, 千葉史子, 神保教広, 瓜田泰久, 新開統子, 高安肇, 中川嘉, 島野仁
- Organizer
  日本外科代謝栄養学会第57 回学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 腸肝転写因子CREBHはSREBPの活性を制御し、動脈硬化発症を抑制する2020
- Author(s)
  中川嘉, 王雨農, 韓松伊, 水之江雄平, 荒木雅弥, 関谷元博, 松坂賢, 島野仁
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K21611
[Presentation] 小腸切除モデルマウスを用いた小腸切除後の栄養トランスポーター関連遺伝子発現変化の検討2020
- Author(s)
  佐々木理人、小野健太郎、堀口比奈子、白根和樹、根本悠里、田中尚、相吉翼、千葉史子、神保教広、瓜田泰久、新開統子、高安肇、中川嘉、島野　仁、増本幸二
- Organizer
  第35回日本臨床栄養代謝学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 脂肪酸伸長酵素Elovl6による神経新生の制御機構解明2020
- Author(s)
  大野博, 松坂賢, 本村香織, 志村拓哉, 宮本崇史, 関谷元博, 中川嘉, 島野
- Organizer
  日本臨床分子医学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 転写因子SREBP-1aによる腸管内脂質制御が腸管内部構造に与える影響の検討2020
- Author(s)
  荒木雅弥、中川嘉、韓松伊、水之江雄平、王農雨、松坂賢、関谷元博、矢作直也、島野　仁
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢、久芳素子、小安さおり、本村香織、大野博、Sharma R、武内謙憲、矢作直也、宮本崇史、関谷元博、中川嘉、島野　仁
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢, 久芳素子, 小安さおり, 本村香織, 大野博, Rahul Sharma, 武内謙憲, 矢作直也, 宮本崇史, 関谷元博, 中川嘉, 島野仁
- Organizer
  第 63 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 新規プロテアーゼによるSREBP-1活性化制御機構の解明2020
- Author(s)
  韓松伊、中川嘉、宮本崇史、松坂賢、関谷元博、島野仁
- Organizer
  第43回日本分子生物学会年会（オンライン開催）
- Data Source
  KAKENHI-PROJECT-19K11713
[Presentation] 小腸切除モデルマウスを用いた小腸切除後の栄養トランスポーター関連遺伝子発現変化の検討2020
- Author(s)
  佐々木理人, 小野健太郎, 堀口比奈子, 白根和樹, 根本悠里, 田中尚, 相吉翼, 千葉史子, 神保教広, 瓜田泰久, 新開統子, 高安肇, 中川嘉, 島野仁, 増本幸二
- Organizer
  第35回日本臨床栄養代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 転写因子SREBP-1aによる腸管内脂質制御が腸管内部構造に与える影響の検討2020
- Author(s)
  荒木雅弥, 中川嘉, 韓松伊, 水之江雄平, 王農雨, 松坂賢, 関谷元博, 矢作直也, 島野仁
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20K21611
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢, 久芳素子, 小安さおり, 本村香織, 大野博, Rahul Sharma, 武内謙憲, 矢作直也, 宮本崇史, 関谷元博, 中川嘉, 島野仁
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K21611
[Presentation] Elucidation of Apoa1 Gene Regulatory Mechanism Through Searching Causal Single-Nucleotide Variants2020
- Author(s)
  Aita Y, Yahagi N, Takeuchi Y, Ho MH, Saber ZM, Huyan Y, Murayama Y, Shikama A, Masuda Y, Izumida Y, Sekiya M, Nakagawa Y, Matsuzaka T, Kawakami Y, Shimano H
- Organizer
  American Heart Association Scientific Sessions 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 腸肝転写因子CREBHはSREBPの活性を制御し、動脈硬化発症を抑制する(会議録)2020
- Author(s)
  中川嘉, 王雨農, 韓松伊, 水之江雄平, 荒木雅弥, 関谷元博, 松坂賢, 島野仁
- Organizer
  第 63 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] Causal SNV探索を通じたApoA1遺伝子の新たな発現調節機構の解明2020
- Author(s)
  曾田雄一、矢作直也、武内謙憲、何敏熙、Zahra MS、呼延宜人、村山友樹、志鎌明人、升田紫、泉田欣彦、関谷元博、中川嘉、松坂賢、川上康、島野　仁
- Organizer
  第52回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢, 久芳素子, 小安さおり, 本村香織, 大野博, Rahul Sharma, 武内謙憲, 矢作直也, 宮本崇史, 関谷元博, 中川嘉, 島野仁
- Organizer
  第89回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] グルココルチコイドによるGR-Bmal/Clock複合体を介した時計遺伝子Nr1d1の抑制性転写制御機構2020
- Author(s)
  村山友樹, 矢作直也, 武内謙憲, 會田雄一, 何敏煕, Mehrazad Saber Zahra, 志鎌明人, 升田紫, 泉田欣彦, 宮本崇史, 関谷元博, 中川嘉, 松坂賢, 大崎芳典, 菅野洋子, 岩崎仁, 鈴木浩明, 川上康, 島野仁
- Organizer
  第89回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢、久芳素子、小安さおり、本村香織、大野博、Sharma R、武内謙憲、矢作直也、宮本崇史、関谷元博、中川嘉、島野　仁
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 細胞外マトリックスに起因する貪食細胞機能調節と病態形成2019
- Author(s)
  伊豫田拓也、中川嘉、島野仁、深井文雄
- Organizer
  第36回　薬学会・九州山口支部大会
- Data Source
  KAKENHI-PROJECT-17K08606
[Presentation] 細胞外マトリックスによるマクロファージ機能調節と病態形成2019
- Author(s)
  伊豫田拓也、中川嘉、島野仁、深井文雄
- Organizer
  第20回　Pharmaco-Hematology シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08606
[Presentation] CREBH regulates ChREBP-mediated hepatic fructose metabolism2019
- Author(s)
  Yunong Wang, Yoshimi Nakagawa, Song-Iee Han, Kae Kumagai, Yuhei Mizunoe, Masaya Araki, Motohiro Sekiya, Takashi Matsuzaka, Hitoshi Shimano
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H03253
[Presentation] SOCS3 Deficiency on a High-Fat Diet Accelerates Systemic Inflammation and Results in Lethal Myeloid Hematopoiesis without Obesity and Adiposity.2019
- Author(s)
  Cho K, Ushiki T, Ishiguro H, Katagiri T, Suwabe T, Hirai H, Nakagawa Y, Masuko M, Alexander W, Shimano H, Sone H.
- Organizer
  79th American Diabetes Association Scientific Sessions (ADA).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11716
[Presentation] 細胞外マトリックスによるマクロファージ機能調節と病態形成2019
- Author(s)
  伊豫田拓也，中川嘉，島野仁，深井文雄
- Organizer
  第20回 Pharmaco-Hematology シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08606
[Presentation] 新規プロテアーゼによるSREBP-1活性化制御機構の解明2019
- Author(s)
  韓松伊、水之江雄平、中川嘉、関谷元博、松坂賢、島野仁
- Organizer
  第５６回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11713
[Presentation] 転写因子CREBHの未成熟型・成熟型による動脈硬化形成に対する二重支配の分子メカニズム2018
- Author(s)
  中川嘉、韓松伊、大石麻代、王雨農、関谷元博、松坂賢、島野仁
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 脂質代謝調節転写因子と動脈硬化・糖尿病2018
- Author(s)
  中川　嘉
- Organizer
  第３３回日本糖尿病合併症学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03253
[Presentation] 脂質異常症新規治療薬 K877 の食餌誘導性肥満に対する効果2018
- Author(s)
  荒木　雅弥、中川　嘉
- Organizer
  第55回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-16H03253
[Presentation] 骨格筋特異的HMG-CoA還元酵素ノックアウトマウスにおける筋障害メカニズム2018
- Author(s)
  島野仁、大崎芳典、村山友樹、水之江雄平、中川嘉
- Organizer
  第4回日本筋学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] リソソーム機能異常が脂肪滴局在タンパク質ペリリピンに及ぼす影響の解析2018
- Author(s)
  水之江雄平、樋上賀一、小林正樹、星野駿介、中川　嘉、島野　仁
- Organizer
  第39回日本肥満学会
- Data Source
  KAKENHI-PROJECT-17H02179
[Presentation] CREB3L3欠損による動脈硬化発症の分子メカニズム2017
- Author(s)
  中川　嘉、関谷　元博、松坂　賢、島野　仁
- Organizer
  第32回日本糖尿病合併症学会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] CREB3L3欠損による動脈硬化発症の分子メカニズム2017
- Author(s)
  中川　嘉、関谷　元博、松坂　　賢、島野　　仁
- Organizer
  第32回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-16H03253
[Presentation] 微小接着環境の変化がもたらす細胞機能調節と加齢性疾患の進展2017
- Author(s)
  伊豫田拓也，横山雅シャラ，大石麻代，王雨農，中川嘉，深井文雄
- Organizer
  第一回東京理科大学ー横浜市立大学合同シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08606
[Presentation] 脳における脂肪酸伸長酵素Elovl6の役割2015
- Author(s)
  大野博、松坂賢、吉田恵里子、伏見友希、所司慶太、中川嘉、矢作直也、山田信博、島野　仁
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脂肪酸伸長酵素Elovl6の欠損はdb/dbマウスの糖尿病の発症・進展を抑制する2015
- Author(s)
  松坂賢、中野雄太、趙会、唐寧、鈴木真璃衣、大野博、中川嘉、矢作直也、山田信博、島野　仁
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脂肪組織におけるin vivo Ad-luc法によるfatty acid synthaseのプロモーター解析2015
- Author(s)
  西　真貴子、矢作直也、武内謙憲、志鎌明人、戸谷直樹、大屋友華里、朴　賢英、曾田雄一、沢田義一、松坂　賢、中川　嘉、升田　紫、泉田欣彦、飯塚陽子、山田信博、門脇　孝、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脂肪酸伸長酵素Elovl6の骨・軟骨細胞における役割の検討2015
- Author(s)
  菊池愛美、嶋田昌子、松坂賢、石井清明、中川嘉、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 栄養飢餓により活性化する転写因子とCREB3L3は肥満及び糖代謝を改善する2015
- Author(s)
  佐藤　葵、中川　嘉、松坂　賢、島野　仁
- Organizer
  第27回分子糖尿病学シンポジウム
- Place of Presentation
  丸ビルホール（東京）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] CREB3L3 regulates energy metabolism in enterohepatic circulation2015
- Author(s)
  Yoshimi Nakagawa, Hitoshi Shimano
- Organizer
  第47回日本動脈硬化学会総会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2015-07-10
- Invited
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] Leptin遺伝子発現調節機構のin vivo Ad-luc解析2015
- Author(s)
  戸谷直樹、矢作直也、武内謙憲、西　真貴子、沢田義一、朴　賢英、曾田雄一、大屋友華里、志鎌明人、松坂賢、中川　嘉、升田　紫、久保田みどり、泉田欣彦、門脇　孝、山田信博、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 転写因子CREB3L3による絶食時エネルギー代謝調節機構2015
- Author(s)
  中川　嘉、佐藤　葵、大崎芳典、松坂　賢、山田信博、島野　仁
- Organizer
  第52回日本臨床分子医学会学術集会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脂肪酸伸長酵素Elovl6の欠損はdb/dbマウスの2型糖尿病の発症・進展を抑制する2015
- Author(s)
  趙会、松坂　賢、中野雄太、Nie Tang、鈴木真璃衣、武内謙憲、岩崎　仁、小林和人、矢藤　繁、鈴木浩明、矢作直也、中川　嘉、山田信博、島野　仁
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] トン食摂食時のエネルギー代謝に関わる新たな遺伝子発現調節機構2015
- Author(s)
  中川　嘉、佐藤　葵、松坂　賢、山田信博、島野　仁
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 転写因子CREB3L3による絶食時エネルギー代謝調節機構2015
- Author(s)
  中川　嘉、佐藤　葵、大崎　芳典、松坂　賢、山田　信博、島野　仁
- Organizer
  第52回日本臨床分子医学会学術集会
- Place of Presentation
  みやこめっせ(京都府京都市)
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] Creb313の動脈硬化形成における役割2015
- Author(s)
  柳下友花、中川嘉、奥田佳菜子、八木豊美、佐藤葵、及川総香、松坂賢、岩崎仁、小林和人、矢作直也、矢藤繁、鈴木浩明、山田信博、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 転写因子Creb313の動脈硬化進展に及ぼす影響2015
- Author(s)
  柳下友花、中川　嘉、佐藤　葵、大崎芳典、松坂　賢、山田信博、島野　仁
- Organizer
  第52回日本臨床分子医学会学術集会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 転写因子CREBHの動脈硬化発症進展における役割2014
- Author(s)
  中川　嘉、奥田　佳菜子、八木　豊美、折原　佳奈、佐藤　葵、及川　総香、松坂　賢、嶋田　昌子、岩崎　仁、小林　和人、高橋　昭光、矢藤　繁、矢作　直也、鈴木　浩明、山田　信博、島野　仁
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府・大阪)
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 転写因子CREBH による動脈硬化発症進展における役割2014
- Author(s)
  中川嘉、奥田佳菜子、八木豊美、折原佳奈、佐藤葵、及川総香、松坂賢、嶋田昌子、岩崎仁、小林和人、矢藤繁、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学(北海道・札幌)
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 糖・脂質代謝調節における絶食応答転写因子CREBHの機能2013
- Author(s)
  中川　嘉
- Organizer
  日本糖尿病学会
- Place of Presentation
  熊本
- Year and Date
  2013-05-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-23126502
[Presentation] 糖・脂質代謝調節におけるCREBH-PPARa相互作用の解明2013
- Author(s)
  中川嘉、佐藤葵、松坂賢、岩崎仁、小林和人、矢藤繁、嶋田昌子、矢作直也、山田信博、鈴木浩明、島野仁
- Place of Presentation
  熊本
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] 糖・脂質代謝調節における絶食応答転写因子CREBHの機能2013
- Author(s)
  中川嘉、島野仁
- Organizer
  第56回日本糖尿病学会
- Place of Presentation
  熊本シンポジウム
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割2012
- Author(s)
  松坂賢、齋藤亮、唐澤直義、松森理恵、煙山紀子、中川嘉、石井清朗、岩崎仁、小林和人、矢藤繁、高橋昭光、曽根博仁、鈴木浩明、矢作直也、山田信博、島野仁
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-24659441
[Presentation] Elovl6 promotesnonalcoholic steatohepatitis in mice andhumans2012
- Author(s)
  Takashi Matsuzaka, Tang Nie, NorikoSuzuki-Kemuriyama, Motoko Kuba, YoshimiNakagawa, Kiyoaki Ishii, Masako Shimada,Kazuto Kobayashi, Shigeru Yatoh, AkimitsuTakahashi, Hirohito Sone, Naoya Yahagi,Hiroaki Suzuki, Makoto Nakamuta, NobuhiroYamada, Hitoshi Shim
- Organizer
  9th IDF-WPR Congress and 4th AASDScientific Meeting
- Place of Presentation
  国立京都国際会館, 京都
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-24659441
[Presentation] Deletion of Elovl6 protects against the failure of pancreatic beta-cell mass and function in db/db mice.2012
- Author(s)
  Yuta Nakano, Takashi Matsuzaka, Nie Tang, Marii Suzuki, Noriko Suzuki-Kemuriyama, Motoko Kuba, Keita Shoshi, Tomotaka Yokoo, Yoshimi Nakagawa, Kiyoaki Ishii, Masako Shimada, Hitoshi Iwasaki, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Naoya Yahagi, Hiroaki Suzuki, Nobuhiro Yamada, Hitoshi Shimano.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] Deletion of Elovl6 protects against thefailure of pancreatic beta-cell mass andfunction in db/db mice2012
- Author(s)
  Yuta Nakano, Takashi Matsuzaka, NieTang, Marii Suzuki, Noriko Suzuki-Kemuriyama, Motoko Kuba, KeitaShoshi, Tomotaka Yokoo, Yoshimi Nakagawa,Kiyoaki Ishii, Masako Shimada, HitoshiIwasaki, Kazuto Kobayashi, Shigeru Yatoh,Akimitsu Takahashi, Naoya Yahagi, Hi
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡、福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-24659441
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割2012
- Author(s)
  松坂賢、斎藤亮、唐澤直義、松森理恵、煙山紀子、中川嘉、石井清朗、岩崎仁、小林和人、矢藤繁、高橘昭光、曽根博仁、鈴木浩明、矢作直也、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] Elov16 promotes nonalcoholic steatohepatitis in mice and humane.2012
- Author(s)
  Takashi Matauzaka, Tang Nie, Noriko Suzuki-Kemuriyama, Motoko Kuba, Yoshimi Nakagawa, Kiyoaki Ishii, Masako Shimada, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Hirohito Sone, Naoya Yahagi, Hiroaki Suzuki, Makoto Nakamuta, Nobuhiro Yamada, Hitoshi Shimano.
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 骨格筋における転写因子TFE3の糖・蛋白代謝に対する効果2011
- Author(s)
  飯田薫子,中彩乃,中川嘉,島野仁
- Organizer
  第65回日本栄養・食糧学会大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-21500677
[Presentation] CREBH によるエネルギー代謝調節機構と生活習慣病に対する機能の解明2011
- Author(s)
  中川嘉、山田信博
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路島
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] CREBH is the new regulator of hepatic gene expression in fasted state2010
- Author(s)
  Yoshimi Nakagawa, Motoki Mikami, Akiko Shingyouuchi,Naoko Tokushige, Nobuhiro Yamada, Hitoshi Shimano
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  岐阜
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] 肥満病態モデルマウスにおける糖・脂質代謝制御因子CREBH の影響2010
- Author(s)
  藤本ゆり,中川嘉,徳重直子,三上素樹,新行内晶子,木綿梢里,佐藤葵,松坂賢,石井清朗,山田信博,島野仁
- Organizer
  BMB2010 第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] エネルギー代謝関連転写因子TFE3の骨格筋における機能解析2010
- Author(s)
  中彩乃,飯田薫子,岩崎仁,中川嘉,山田信博,島野仁
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県
- Data Source
  KAKENHI-PROJECT-21500677
[Presentation] The liver-enriched transcriptionfactor CREBH is nutritionally regulated and activated by fatty acids and PPARa in vitro and in vivo.2010
- Author(s)
  三上素樹,中川嘉,徳重直子,新行内晶子,木綿梢里,藤本ゆり,佐藤葵,松坂賢,石井清朗,山田信博,島野仁
- Organizer
  BMB2010第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] Functional analysis of TFE3, the energy metabolism related transcription factor, in skeletal muscles2010
- Author(s)
  Naka A, Iida K, Iwasaki H, Nakagawa Y, Yamada N, Shimano H.
- Organizer
  15th Annual Congress of the European College of Sport Science(ECSS)
- Place of Presentation
  Antalya, Turkey
- Data Source
  KAKENHI-PROJECT-21500677
[Presentation] 生活習慣病における脂質代謝制御因子CREBH の機能解析2010
- Author(s)
  徳重直子,中川嘉,三上素樹,新行内晶子,藤本ゆり,木綿梢里,佐藤葵,松坂賢,石井清朗、山田信博,島野仁
- Organizer
  BMB2010第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] Nobuhiro YAMADA CREBH is the new transcription factor for hepatic energy metabolism in fasted state2010
- Author(s)
  Yoshimi NAKAGAWA, Hitoshi SHIMANO
- Organizer
  14th international Congress of Endocrinology (ICE2010) Official Satellite Symposia
- Place of Presentation
  Kyoto Japan
- Year and Date
  2010-03-31
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] Functional analysis of TFE3, the energy metabolism related transcription factor, in skeletal muscles.2010
- Author(s)
  Naka A, Iida K, Iwasaki H, Nakagawa Y, Yamada N, Shimano H
- Organizer
  15^<th> Annual Congress of the European College of Sport Science (ECSS)
- Place of Presentation
  Antalya, Turkey
- Data Source
  KAKENHI-PROJECT-21500677
[Presentation] 新規生活習慣病関連転写因子TFE3の骨格筋における機能解析2009
- Author(s)
  岩崎仁,島野仁,中川嘉,飯田薫子、松坂賢,石井清朗,小林和人,矢藤繁,高橋昭光,鈴木浩明,山田信博
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21500677
[Presentation] 脂質代謝調節におけるFGF21を中心とした転写因子クロストークの解明2009
- Author(s)
  中川嘉, 徳重直子, 新行内晶子, 松坂賢, 石井清朗, 浦山修, 山田信博, 島野仁
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 肝臓特異的発現転写因子CREB-Hの生活習慣病病態の分子メカニズム2009
- Author(s)
  中川嘉
- Organizer
  日本内分泌学会総会
- Place of Presentation
  前橋
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 新規生活習慣病関連転写因子TFE3の骨格筋における機能解析2009
- Author(s)
  岩崎仁, 島野仁, 中川嘉, 飯田薫子, 他
- Organizer
  第52回日本糖尿病学会年次学術集会大会
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21500677
[Presentation] FGF21を制御する転写因子CREBHは生活習慣病を改善する2009
- Author(s)
  中川嘉、清水英寿、矢部祥子、島野仁、松坂賢、石井清明、高橋昭光、矢藤繁、鈴木浩明、浦山修、山田信博
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 肝臓におけるエネルギー代謝調節因子TFE3のメタボリックシンドロームへの作用メカニズム2008
- Author(s)
  中川嘉
- Organizer
  日本農芸化学会2008年度会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] 肝臓におけるエネルギー代謝調節因子TFE3のメタボリックシンドロームへの作用メカニズム2008
- Author(s)
  中川嘉
- Organizer
  日本農芸化学会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19651082
[Presentation] 骨格筋におけるTFE3の機能解析2008
- Author(s)
  岩崎仁, 島野仁, 中川嘉, 松坂賢, 石井清朗, 小林和人, 矢藤繁, 高橋昭光, 鈴木浩明, 山田信博
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] 肝臓特異的発現転写因子CREB-H の生活習慣病病態への機能解析2008
- Author(s)
  中川嘉
- Organizer
  BMB2008(第31回目本分子生物学会年会・第81回目本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20591043
[Presentation] 肝臓特異的発現転写因子CREB-Hの生活習慣病病態への機能解析2008
- Author(s)
  中川嘉, 矢部祥子, 島野仁, 浦山修, 山田信博
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 骨格筋特異的に発現するTFE3 の解析2008
- Author(s)
  岩崎仁, 島野仁, 中川嘉, 松坂賢, 小林和人, 矢藤繁, 高橋昭光, 鈴木浩明, 山田信博
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] 肝臓におけるエネルギー代謝調節因子TFE3のメタボリックシンドロームへの作用メカニズム2008
- Author(s)
  中川嘉
- Organizer
  日本農芸化学会2008年度会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 肝臓特異的発現転写因子CREB-Hの生活習慣病病態への機能解析2008
- Author(s)
  中川嘉
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19651082
[Presentation] 骨格筋におけるTFE3の機能解析2008
- Author(s)
  岩崎仁, 島野仁, 中川嘉, 松坂賢, 石井清朗, 小林和人, 矢藤繁, 高橋昭光, 鈴木浩明, 山田信博
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 肝臓特異的発現転写因子CREB-Hの生活習慣病病態への機能解析2008
- Author(s)
  中川嘉
- Organizer
  BMB2008(第31回目本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19651082
[Presentation] 肝臓におけるエネルギー代謝調節因子 TFE3 のメタボリックシンドロームへの作用メカニズム2008
- Author(s)
  中川嘉
- Organizer
  日本農芸化学会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 肝臓特異的発現転写因子CREB-Hの生活習慣病病態への機能解析2008
- Author(s)
  中川嘉
- Organizer
  BMB2008(第31回目本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] TFE3による脂肪細胞の分化への影響2007
- Author(s)
  中川嘉、島野仁、岩崎仁、松坂賢、高橋昭光、鈴木浩明、山田信博
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] TFE3による脂肪細胞の分化への影響2007
- Author(s)
  中川嘉、島野仁、岩崎仁、松坂賢、高橋昭光、鈴木浩明、山田信博
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19689019
[Presentation] 糖・脂質代謝調節におけるPPARa-CREBHの相互作用の解明
- Author(s)
  中川　嘉
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 糖・脂質代謝調節における絶食応答転写因子CREBHの機能
- Author(s)
  中川　嘉
- Organizer
  日本糖尿病学会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] 糖・脂質代謝調節におけるCREBH-PPARa相互作用の解明
- Author(s)
  中川　嘉
- Organizer
  日本糖尿病学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] 非アルコール性脂肪性肝炎における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  松坂賢、渥美綾香、唐寧、煙山紀子、久芳素子、中川嘉、嶋田昌子、小林和人、矢藤繁、高橋昭光、曽根博仁、矢作直也、鈴木浩明、中牟田誠、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 脂肪酸伸長酵素Elovl6の欠損は高コレステロール食誘導性脂肪肝を改善する
- Author(s)
  久芳素子、松坂賢、煙山紀子、唐ネ、大野博、中川嘉、矢藤繁、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスはショ糖嗜好性が亢進する
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] FGF21を介した転写因子CREBHによるエネルギー代謝調節機構
- Author(s)
  中川　嘉
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 転写因子CREBHによる肝臓を起点としたエネルギー代謝変化のメカニズム
- Author(s)
  中川　嘉
- Organizer
  第43回日本栄養・食糧学会　北海道支部会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 膵ベータ細胞における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  唐ネ、松坂賢、鈴木真璃衣、中野雄太、煙山（鈴木）紀子、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 糖・脂質代謝調節における絶食応答転写因子CREBHの機能
- Author(s)
  中川　嘉
- Organizer
  第56回日本糖尿病学会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスの摂食行動解析
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24390230

1. SHIMANO Hitoshi (20251241)

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37. ITO Hiroaki

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38. ITO Masahiko

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39. IZUMIDA Yoshihiko

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42. FUJIMURA Tsutomu

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Nakagawa Yoshimi 中川 嘉

NAKAGAWA Yoshimi 中川 嘉

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The mechanism of systemic nutrient metabolism through the maintenance of small intestinal structure and intestinal environment by the interaction of small intestinal constituent cellsPrincipal Investigator

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Elucidation of the mechanism of liver cancer induced by abnormal lipid metabolism in enterohepatic associationPrincipal Investigator

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The effects of SREBP-1a on intestine homeostasis are determined using intestine- or macrophage- specific SREBP-1a KO micePrincipal Investigator

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Analysis of metabolic diseases targeting nutrient complex associated inflammation caused from enterohepatic circulationPrincipal Investigator

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Nakagawa Yoshimi 中川嘉

NAKAGAWA Yoshimi 中川嘉