Igarashi Jotaro 五十嵐城太郎

… Alternative Names

IGARASHI Jotaro 五十嵐城太郎

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Researcher Number	80375162
Other IDs	https://orcid.org/0000-0002-6165-3350
Affiliation (Current)	2024: 福島県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2014 – 2016: 福島県立医科大学, 医学部, 准教授 2011 – 2012: 福島県立医科大学, 医学部, 准教授 2007 – 2010: Tohoku University, 多元物質科学研究所, 助教 2004: Tohoku University, Institute of Multidisciplinary Research for Advanced Materials, Research Associate, 多元物質科学研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / Risk sciences of radiation and chemicals Except Principal Investigator 環境影響評価(含放射線生物学) / 環境保全 / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator ヘム / ヘム調節インヒビター / 結晶化 / 翻訳開始因子キナーゼ / 結晶構造解析 / ヘム制御モチーフ / S-ニトロシル化 / 自己リン酸化 / 一酸化窒素 / タンパク質間相互作用 … More / ヒ素 / グロビン / X線結晶構造解析 / 水酸化 / 酸素 / 2-オキソグルタル酸 / 鉄 / 質量分析 / 脱リン酸化 / プロテアソーム / 肺がん / 過酸化水素 / 翻訳制御 / CPモチーフ / ヘム調節キナーゼ … More Except Principal Investigator シグナル伝達 / Signal transduction / Sensor enzyme / 遺伝子工学 / 一酸化窒素 / cAMP / センサー酵素 / 分子スイッチ / 赤血球 / 転写因子 / ヘム / NO / 蛋白合成 / 環境汚染物質 / Transcription factor / Circadian rhythms / Environmental pollutants / NO synthase / synthesis / Protein translation / Heme / ポルフィリン / キナーゼ / 軸配位子 / 部位特異的変異 / 蛋白翻訳・合成 / センサー / 生物時計 / NO合成酵素 / 蛋白質翻訳・合成 / redox states / Protein-protein interaction / Protein microarray / Heme sensor / Molecular switch / チトクロムP450 / 薬物代謝 / キメラ / 電子移動 / 環境ホルモン / シトクロムP450 / シグナル / 蛋白-蛋白相互作用 / 酸化還元状態 / タンパク-タンパク相互作用 / プロテイン・マイクロアレイ / ヘムセンサー / プロテインマイクロアレイ / PASドメイン / NOガス / 水銀イオン / DNA結合 / 体内時計 / 蛋白質合成 / ガスセンサー / ヘム制御酵素・蛋白質 / 水銀 / 環境汚染 / ヘム鉄 / 時計遺伝子 / NO,ヘム Less

Molecular mechanism of heme-regulated inhibitor (HRI) under stress conditionsPrincipal Investigator
- Principal Investigator
  
  Igarashi Jotaro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Fukushima Medical University
ＯＧＦＯＤ１による翻訳開始因子キナーゼの水酸化Principal Investigator
- Principal Investigator
  
  五十嵐城太郎
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Fukushima Medical University
翻訳開始因子キナーゼにおける活性酸素シグナル伝達機構の解明Principal Investigator
- Principal Investigator
  
  五十嵐城太郎
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
The role of heme-binding, phosphorylation, and degradation in heme-regulated eukaryotic initiation factor 2α kinase (HRI)Principal Investigator
- Principal Investigator
  
  IGARASHI Jotaro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Interaction of heme and nitric oxide with heme-regulated inhibitor (HRI)Principal Investigator
- Principal Investigator
  
  IGARASHI Jotaro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Destruction of the biological clock system by environmental contaminants : Crosstalk between heme, NO, protein synthesis and clock genes
- Principal Investigator
  
  SHIMIZU Toru
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
Analyses of Porphyria Caused by Environmental Pollutants : Concerted Reaction and Tempo of Heme and Porphyrin Syntheses
- Principal Investigator
  
  SHIMIZU Toru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Tohoku University
Construction of Environmental Biremediation Enzymes Whose Catalysis is Regulated by Light and Molecular Switches
- Principal Investigator
  
  SHIMIZU Toru
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境保全
- Research Institution
  Tohoku University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] Gas Sensors : Developments, Efficacy and Safety2011
- Author(s)
  五十嵐城太郎
- Publisher
  Nova Science
- Data Source
  KAKENHI-PUBLICLY-23117504
[Book] Handbook of Porphyrin Science Vol 152011
- Author(s)
  Jotaro Igarashi(分担執筆)
- Publisher
  World Scientific
- Data Source
  KAKENHI-PROJECT-21770130
[Book] Handbook of Porphyrin Science Vol.152011
- Author(s)
  Jotaro Igarashi
- Publisher
  World Scientific
- Data Source
  KAKENHI-PUBLICLY-21117501
[Book] Emerging Role of Heme as a Signal and the Gas-Sensing Site : Heme-Sensing and Gas-Sensing Proteins.Handbook of Porphyrin Science (Kadish, K.M., Smith, K.M., Guilard, R.Eds.)2011
- Author(s)
  Igarashi, J., Kitanishi, K., Shimizu, T.
- Publisher
  World Scientific (Hackensack, NJ, USA)
- Data Source
  KAKENHI-PROJECT-21770130
[Book] Circadian Rhythms : Biology, Cognition and Disorders2011
- Author(s)
  五十嵐城太郎
- Publisher
  Nova Science
- Data Source
  KAKENHI-PUBLICLY-23117504
[Book] 酵素利用技術体系(小宮山眞編)(シトクロムP450.)2010
- Author(s)
  五十嵐城太郎, 清水透
- Publisher
  エヌ・ティー・エス(東京)
- Data Source
  KAKENHI-PROJECT-21770130
[Book] 酵素利用技術体系2010
- Author(s)
  五十嵐城太郎(分担執筆)
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-21770130
[Book] 酵素利用技術体系2010
- Author(s)
  五十嵐城太郎
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PUBLICLY-21117501
[Book] 他のヘムーチオレートタンパク質の構造と機能2009
- Author(s)
  五十嵐城太郎, 清水透 (分担執筆)
- Data Source
  KAKENHI-PROJECT-17101002
[Book] の分子生物学第2版(大村恒雄, 石村巽, 藤井義明編)(のヘムーチオレート蛋白質の構造と機能.P450)2009
- Author(s)
  五十嵐城太郎, 清水透, 他
- Publisher
  講談社(東京)
- Data Source
  KAKENHI-PROJECT-21770130
[Book] P450の分子生物学(大村恒雄、石村巽、藤井義明編)2009
- Author(s)
  五十嵐城太郎
- Total Pages
  303
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Leu65 in the heme distal side is critical for the stability of the Fe(II)-O_2 complex of YddV, a globin-coupled oxygen sensor diguanylate cyclase2012
- Author(s)
  五十嵐城太郎
- Journal Title
  
  J.Inorg.Biochem.
  
  Volume: 108 Pages: 1251-1257
- DOI
  10.1016/j.jinorgbio.2011.09.019
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117504, KAKENHI-PROJECT-23570136, KAKENHI-PLANNED-20108007, KAKENHI-PROJECT-23350095
[Journal Article] ヘムによる翻訳開始因子制御の分子機構2012
- Author(s)
  五十嵐城太郎
- Journal Title
  
  福島県立医科大学総合科学教育研究センター紀要
  
  Volume: 1 Pages: 16-21
- Data Source
  KAKENHI-PUBLICLY-23117504
[Journal Article] Hydrogen sulfide stimulates the catalytic activity of a heme-regulated phosphodiesterase from Escherichia coli (Ec DOS)2012
- Author(s)
  五十嵐城太郎
- Journal Title
  
  J.Inorg.Biochem.
  
  Volume: 109C Pages: 1251-1257
- DOI
  10.1016/j.jinorgbio.2012.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117504
[Journal Article] Phosphorylation of a heme-regulated eukaryotic initiation factor 2α kinase enhances the interaction with heat-shock protein 90 and substantially upregulates kinase activity2011
- Author(s)
  五十嵐城太郎
- Journal Title
  
  Protein Pept.Lett.
  
  Volume: 18 Pages: 1251-1257
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117504
[Journal Article] Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase, HRI, and the role of the modification in catalysis2011
- Author(s)
  Jotaro Igarashi
- Journal Title
  
  FEBS Journal
  
  Volume: 278 Pages: 918-928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification2011
- Author(s)
  Jotaro Igarashi
- Journal Title
  
  Journal of Biological Inorganic Chemistry
  
  Volume: 16 Pages: 599-609
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21117501
[Journal Article] A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification2011
- Author(s)
  Jotaro Igarashi
- Journal Title
  
  Journal of Biological Inorganic Chemistry
  
  Volume: 16 Pages: 599-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification.2011
- Author(s)
  Igarashi, J., Kobayashi, K., Matsuoka, A.
- Journal Title
  
  J.Biol.Inorg.Chem. 16
  
  Pages: 599-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase, HRI, and the role of the modification in catalysis2011
- Author(s)
  五十嵐城太郎
- Journal Title
  
  FEBS J.
  
  Volume: 278 Issue: 6 Pages: 918-928
- DOI
  10.1111/j.1742-4658.2011.08007.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117504
[Journal Article] Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase, HRI, and the role of the modification in catalysis2011
- Author(s)
  Jotaro Igarashi
- Journal Title
  
  FEBS Journal
  
  Volume: 278 Pages: 918-928
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21117501
[Journal Article] Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase, HRI, and the role of the modification in catalysis.2011
- Author(s)
  Igarashi, J., Sasaki, T., Kobayashi, N., Yoshioka, S., Matsushita, M., Shimizu, T.
- Journal Title
  
  FEBS J. 278
  
  Pages: 918-928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Identification and functional and spectral characterization of a globin-coupled histidine kinase from Anaeromyxobacter sp.Fw109-52011
- Author(s)
  五十嵐城太郎
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Issue: 41 Pages: 35522-35534
- DOI
  10.1074/jbc.m111.274811
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117504, KAKENHI-PROJECT-23570136
[Journal Article] Heme binding characteristics of the isolated PAS-B domain of mouse Per2, a transcriptional regulatory factor associated with circadian rhythms.2011
- Author(s)
  Hayasaka, K., Kitanishi, K., Igarashi, J., Shimizu, T.
- Journal Title
  
  Biochim.Biophys.Acta 1814
  
  Pages: 326-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification2011
- Author(s)
  五十嵐城太郎
- Journal Title
  
  J.Biol.Inorg.Chem.
  
  Volume: 16 Issue: 4 Pages: 599-609
- DOI
  10.1007/s00775-011-0761-3
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117504, KAKENHI-PROJECT-23570136
[Journal Article] Thiolate with alpha-lipoic acid remediates depressive behavior of mice induced by methyl-mercury2010
- Author(s)
  K. Kitanishi, J. Igarashi, T. Shimizu
- Journal Title
  
  Current Topic in Toxicology (in press)
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Thiolate with α-lipoic acid remedies depressive behavior of mice induced by methyl-mercury.2010
- Author(s)
  Kitanishi, K., Igarashi, J., Shimizu, T.
- Journal Title
  
  Curr.Top.Toxicol. 6
  
  Pages: 23-29
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Catalysis and oxygen binding of Ec DOS, a heme-based oxygen-sensor enzyme from Escherichia coli.2010
- Author(s)
  Kobayashi, K., Tanaka, A., Takahashi, H., Igarashi, J., Ishitsuka, Y., Yokota, N., Shimizu, T.
- Journal Title
  
  J.Biochem. 148
  
  Pages: 693-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Important roles of Tyr43 at the putative heme distal side in oxygen recognition and stability of the Fe(II)-O 2 complex of YddV, a globin-coupled heme-based oxygen sensor diguanylate cyclase.2010
- Author(s)
  Kitanishi, K., Kobayashi, K., Kawamura, Y., Ishigami, I., Ogura, T., Nakajima, K., Igarashi, J., Tanaka, A., Shimizu, T.
- Journal Title
  
  Biochemistry 49
  
  Pages: 10381-10393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy.2009
- Author(s)
  Ji, H., Tan, S., Igarashi, J., Li, H., Derrick, M., Martasek, P., Roman, L., Vasquez-Vivar, J., Poulos, T.L., Silverman, R.B.
- Journal Title
  
  Ann.Neurol. 65
  
  Pages: 209-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors2009
- Author(s)
  五十嵐城太郎
- Journal Title
  
  Journal of Medicinal Chemistry 52
  
  Pages: 2060-2066
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21117501
[Journal Article] Role of Phe113 at the distal side of the heme domain of an oxygen-sensor (Ec DOS) in the characterization of the heme environment.2009
- Author(s)
  Ito, S., Araki, Y., Tanaka, A., Igarashi, J., Wada, T., Shimizu, T.
- Journal Title
  
  J.Inorg.Biochem. 103
  
  Pages: 989-996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.2009
- Author(s)
  Igarashi, J., Li, H., Jamal, J., Ji, H., Fang, J., Lawton, G., Silverman, R.B., Poulos, T.L.
- Journal Title
  
  J.Med.Chem. 52
  
  Pages: 2060-2066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] The FG loop of a heme-based gas sensor enzyme, Ec DOS, functions in heme binding, autoxidation and catalysis.2009
- Author(s)
  Ito, S., Igarashi, J., Shimizu, T.
- Journal Title
  
  J.Inorg.Biochem. 103
  
  Pages: 1380-1385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770130
[Journal Article] Role of Phe113 at the distal side of the heme domain of an oxygen-sensor (Ec DOS) in the characterization of the heme environment2009
- Author(s)
  S. Ito, Y. Araki, A. Tanaka, J. Igarashi, T. Wada, T. Shimizu
- Journal Title
  
  J.Inorg.Biochem. 103
  
  Pages: 989-996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] The FG loop of a heme-based gas sensor enzyme, Ec DOS, functions in heme binding, autoxidation and catalysis2009
- Author(s)
  S. Ito, J. Igarashi, T. Shimizu
- Journal Title
  
  J.Inorg.Biochem. 103
  
  Pages: 1380-1385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Arg97 at the heme-distal side of the isolated heure-bound PAS domain of a heure-based oxygen sensor from Escherichia coli (EcDOS) plays critical roles in autoxidation and binding to gases, particularly O_22008
- Author(s)
  Ishitsuka, Y., Araki, Y., Tanaka, A., Igarashi, J., Ito, O. and Shimizu, T.
- Journal Title
  
  Biochemistry 47
  
  Pages: 8874-8884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] Heme-binding characteristics of the isolated PAS-A domain of mouse Per2, a transcriptional regulatory factor associated with circadian rhythms2008
- Author(s)
  Kitanishi, K., Igarashi, J., Hayasaka, K., Hikage, N., Saiful, I., Yamauchi, S., Uchida, T., Ishimori, K. and Shimizu, T.
- Journal Title
  
  Biochemistry 47
  
  Pages: 6157-6168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] The role of thiolate-heme proteins, other than the P450 cytochromes, in regulation of heme-sensor proteins2008
- Author(s)
  Jotaro Igarashi
- Journal Title
  
  Acta Chimica Slovenica 55
  
  Pages: 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] Elucidation of the heme-binding site of heme-regualted eIFa kinase (HRI) and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins2008
- Author(s)
  Jotaro Igarashi
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 18782-18791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] The roles of thiolate-heme proteins, other than the P450 cytochromes, in the regulation of heme-sensor proteins2008
- Author(s)
  Igarashi, J., Kitanishi, K., Martinkova, M., Murase, M., Iizuka, A. and Shimizu, T.
- Journal Title
  
  Acta Chim. Slov. 55
  
  Pages: 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] Elucidation of the herne-binding site of heme-regulated elF2α kinase (HRI) and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins2008
- Author(s)
  Igarashi, J., Murase, M., Iizuka, A., Pichierri, F., Martinkova, M. and Shimizu, T.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 18782-18791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] Elucidation of the heme-binding site of heme-regulated eIF2alpha kinase (HRI) and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins2008
- Author(s)
  J. Igarashi, M. Murase, A. Iizuka, F. Pichierri, M. Martinkova, T. Shimizu
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 18782-18791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] ヘムの移動により機能する生体反応・ヘムセンサータンパク質・素とヘム輸送体2008
- Author(s)
  五十嵐城太郎
- Journal Title
  
  化学 63
  
  Pages: 66-67
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] ヘムが移動して機能する生体反応-ヘムの移動により機能する蛋白質・酵素の機能2008
- Author(s)
  五十嵐城太郎、清水透
- Journal Title
  
  化学 63
  
  Pages: 66-67
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] The roles of thiolate-heme proteins, other than the P450 enzyme,…….2008
- Author(s)
  五十嵐城太郎, 他
- Journal Title
  
  Acta Chimica Slovenica 282
  
  Pages: 21301-21307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Arg97 at the heme distal side of the isolated heme-bound PAS domain of a heme-based oxygen sensor from Escherichia coli (Ec DOS) plays critical roles in auto-oxidation and binding to gases, particularly O_22008
- Author(s)
  Y. Ishitsuka, Y. Araki, A. Tanaka, J. Igarashi, O. Ito, T. Shimizu
- Journal Title
  
  Biochemistry 47
  
  Pages: 8874-8884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Heme binding characteristics of the isolated PAS-A domain of mouse Per2, a transcriptional regulatory factor associated with circadian rhythms2008
- Author(s)
  K. Kitanishi, J. Igarashi, K. Hayasaka, N. Hikage, I. Saiful, S. Yamauchi, T. Uchida, K. Ishimori, T. Shimizu
- Journal Title
  
  Biochemistry 47
  
  Pages: 6157-6168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] The roles of thiolate-heme proteins, other than the P450 cytochromes, in the regulation of heme-sensor proteins2008
- Author(s)
  J. Igarashi, K. Kitanishi, M. Martinkova, M. Murase, A. Iizuka, T. Shimizu
- Journal Title
  
  Acta Chim.Slov. 55
  
  Pages: 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Identification of Cys385 in the isolated kinase insertion domain of heme-regulated eIF2α kinase (HRI) as the heme axial ligand by site-directed mutagenesis and spectral characterization2007
- Author(s)
  Hirai, K., Martinkova, M., Igarashi, J., Saiful, I., Yamauchi, S., El-Mashtoly, S. F., Kitagawa, T. and Shimizu, T.
- Journal Title
  
  J. Inorg. Biochem. 101
  
  Pages: 1172-1179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] ドメイン間相互作用による酵素活性の制御2007
- Author(s)
  五十嵐城太郎
- Journal Title
  
  生体の科学 58
  
  Pages: 354-356
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] ドメイン間相互作用による酵素活性の制御2007
- Author(s)
  五十嵐城太郎、田中敦成、清水透
- Journal Title
  
  生体の科学 58
  
  Pages: 354-356
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] Eukaryotic initiation factor 2alpha kinase is a nitric oxide-responsive mercury sensor enzyme : Potent inhibition of catalysis by the mercury cation and reversal by nitric oxide2007
- Author(s)
  M. Martinkova, J. Igarashi, T. Shimizu
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 4109-4114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Eukaryotic initiation factor 2α kinase is a nitric oxide-responsive mercury sensor enzyme : potent inhibition of catalysis by the mercury cation and reversal by nitric oxide2007
- Author(s)
  Martinkova, M., Igarashi, J. and Shimizu, T.
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 4109-4114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770099
[Journal Article] Characterization of heme-regulated eIF2 alpha kinase : Roles of the N-terminal domain in the oligomeric state, heme binding, catalysis, and inhibition2006
- Author(s)
  M. Miksanova, J. Igarashi, M. Minami, I. Sagami, S. Yamauchi, H. Kurokawa, T. Shimizu
- Journal Title
  
  Biochemistry 45
  
  Pages: 9894-9905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a heme-regulated phosphodiesterase from Escherichia coli2006
- Author(s)
  N. Yokota, Y. Araki, H. Kurokawa, O. Ito, J. Igarashi, T. Shimizu
- Journal Title
  
  FEBS J. 273
  
  Pages: 1210-1223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Spectroscopic and DNA-binding characterization of the isolated heme-bound basic helix-loop-helix-PAS-A domain of neuronal PAS protein 2 (NPAS2), a transcription activator protein associated with circadian rhythms2006
- Author(s)
  Y. Mukaiyama, T. Uchida, E. Sato, A. Sasaki, Y. Sato, J. Igarashi, H. Kurokawa, I. Sagami, T. Kitagawa, T. Shimizu
- Journal Title
  
  FEBS J. 273
  
  Pages: 2528-2539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Spectroscopic characterization of the isolated heme-bound PAS-B domain of neuronal PAS domain protein 2 associated with circadian rhythms2005
- Author(s)
  R. Koudo, H. Kurokawa, E. Sato, J. Igarashi, T. Uchida, I. Sagami, T. Kitagawa, T. Shimizu
- Journal Title
  
  FEBS J. 272
  
  Pages: 4153-4162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17101002
[Journal Article] Activation of Heme-regulated Initiation Factor 2α Kinase by Nitric Oxide Is Inducued by the Formation of a Five-coordinated NO-Heme Complex2004
- Author(s)
  J.Igarashi
- Journal Title
  
  Journal of Biological Chemistry 279(16)
  
  Pages: 15752-15762
- Data Source
  KAKENHI-PROJECT-14208066
[Presentation] Hoki myoglobin with unusual autoxidation behavior: Comparative analysis of native protein and H60V mutant2016
- Author(s)
  Kobayashi, G., Igarashi, J., Rei, M., Nishiyama, N., Mizuguchi, T., Matsuoka, A.
- Organizer
  The 22nd International Congress of Zoology and the 87th meeting of Zoological Society of Japan
- Place of Presentation
  宜野湾
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] Ligand sensing mechanism of globin domain of a heme-based oxygen-sensor enzyme, YddV, from Escherichia coli.2016
- Author(s)
  Igarashi, J., Kikuchi, T., Matsuoka, A.
- Organizer
  The 19th International Conference on Oxygen Binding and Sensing Proteins
- Place of Presentation
  Hamburg, Germany
- Year and Date
  2016-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] 酸素センサータンパク質 YddV のグロビンドメインの構造解析2016
- Author(s)
  五十嵐城太郎, 松岡有樹
- Organizer
  日本動物学会平成28年度東北支部大会
- Place of Presentation
  福島
- Year and Date
  2016-07-24
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] 酸素センサータンパク質YddVのリガンド識別機構と活性調節2016
- Author(s)
  五十嵐城太郎, 菊池亨, 松岡有樹
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] 酸素センサータンパク質YddVのグロビンドメインの構造解析2015
- Author(s)
  五十嵐城太郎, 菊池亨, 松岡有樹
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会（BMB2015）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] Stability properties of fish myoglobin from hoki (Macruronus magellanicus)2015
- Author(s)
  Kobayashi, G., Nishiyama, N., Endo, Y., Mizuguchi, T., Igarashi, J., and Matsuoka, A.
- Organizer
  The 9th International Congress of Comparative Physiology and Biochemistry
- Place of Presentation
  Krakow, Poland
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] Crystal structure of isolated heme-bound globin domain of a heme-based oxygen-sensor, YddV, from Escherichia coli.2015
- Author(s)
  Igarashi, J., Kikuchi, T., and Matsuoka, A.
- Organizer
  The 53rd Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  Kanazawa, Japan
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] 酸素センサー酵素Ec DOSのM30A変異体における構造変化2014
- Author(s)
  五十嵐城太郎，清水透
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] 大腸菌で発現させたホキ・ミオグロビンの分子特性2014
- Author(s)
  小林元，遠藤優希，五十嵐城太郎，西山学即，水口亨，松岡有樹
- Organizer
  平成26年度日本水産学会秋季大会
- Place of Presentation
  福岡
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-26340041
[Presentation] ヘム調節インヒビター（HRI）のヘム・リン酸化による活性制御機構2013
- Author(s)
  五十嵐城太郎
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PUBLICLY-23117504
[Presentation] イミダゾール結合による酸素センサー酵素Ec DOSの調節機構の解明2012
- Author(s)
  五十嵐城太郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23117504
[Presentation] 原生生物Tetrahymena pyriformisにみられる短縮型ヘモグロビンの立体構造解析2011
- Author(s)
  五十嵐城太郎
- Organizer
  2011年度福島県生物同好会講演会
- Place of Presentation
  福島
- Year and Date
  2011-08-10
- Data Source
  KAKENHI-PUBLICLY-23117504
[Presentation] 原生生物Tetrahymena pyriformisにみられるヘモグロビンの構造機能解析2011
- Author(s)
  五十嵐城太郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-23117504
[Presentation] ヘム調節インヒビター(HRI)のヘム・リン酸化による反応制御機構2010
- Author(s)
  五十嵐城太郎, 佐々木健彦, 清水透
- Organizer
  日本生化学会東北支部第76回例会・シンポジウムム
- Place of Presentation
  福島
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Molecular mechanism of NO-induced catalytic activation of mouse heme-regulated eukaryotic initiation factor 2α kinase, HRI.2010
- Author(s)
  Igarashi, J., Sasaki, T., Iwashita, J.,Shimizu, T.
- Organizer
  Pacifichem 2010 Congress.Honolulu
- Place of Presentation
  HI, USA.
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Heme-regulated Eukaryotic Initiation Factor 2α Kinase2010
- Author(s)
  Jotaro Igarashi, Toru Shimizu
- Organizer
  Gordon Research Conference on Protein Cofactors, Radicals and Quinones
- Place of Presentation
  U.S.A., Ventura, CA
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] Molecular mechanism of NO-induced catalytic activation of mouse heme-regulated eukaryotic initiation factor 2α kinase, HRI2010
- Author(s)
  Jotaro Igarashi
- Organizer
  Pacifichem 2010 Congress
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PUBLICLY-21117501
[Presentation] Heme-regulated eukaryotic initiation factor 2α kinase associated with protein translation2010
- Author(s)
  Jotaro Igarashi
- Organizer
  Gordon Research Conference on Protein Cofactors, Radicals and Quinones
- Place of Presentation
  Ventura, CA, USA
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] ヘム調節インヒビター(HRI)のヘム・リン酸化による反応制御機構2010
- Author(s)
  五十嵐城太郎
- Organizer
  日本生化学会東北支部第76回例会・シンポジウム
- Place of Presentation
  福島
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] ヘム調節インヒビター(HRI)のヘム・リン酸化による活性調節機構2010
- Author(s)
  五十嵐城太郎
- Organizer
  第33回日本分子生物学会年会・第82回日本生化学会年会合同大会(BMB2010)
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Cysteine Thiolate is the Heme Binding Site of Heme-regulated Transcription Regulatory Factors Associated with Circadian Rhythms2010
- Author(s)
  Kenichi Kitanishi, Jotaro Igarashi, Toru Shimizu
- Organizer
  Gordon Research Conference on Protein Cofactors, Radicals and Quinones
- Place of Presentation
  U.S.A., Ventura, CA
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] NO-induced activation of a heme-sensor, eIF2α kinase, in association with binding to cysteine and heme2010
- Author(s)
  Jotaro Igarashi
- Organizer
  6th International Conference, Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  国立京都国際会館
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PUBLICLY-21117501
[Presentation] NO-induced activation of a heme-sensor, eIF2α kinase, in association with binding to cysteine and heme.2010
- Author(s)
  Igarashi, J., Sasaki, T., Iwashita, J.,Shimizu, T.
- Organizer
  6th International Conference, Biology, Chemistry, and Therapeutic Applications of Nitric Oxide.
- Place of Presentation
  Kyoto,Japan.
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] ヘム調節インヒビター(HRI)のヘム・リン酸化による活性調節機構2010
- Author(s)
  五十嵐城太郎, 佐々木健彦, 清水透
- Organizer
  第33回日本分子生物学会年会・第82回日本生化学会大会合同大会(BMB2010)
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Heme-regulated eukaryotic initiation factor 2α kinase associated with protein translation.2010
- Author(s)
  Igarashi, J.,Shimizu, T.
- Organizer
  Gordon Research Conference on Protein Cofactors, Radicals and Quinones.
- Place of Presentation
  Ventura, CA, USA.
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] The heme-binding site of the heme-regulated inhibitor (HRI), and the role of heme regulatory motif in heme sensing.2009
- Author(s)
  Igarashi, J.,Murase, M., Shimizu, T.
- Organizer
  16th International Conference on Cytochrome P450, Biochemisty, Biphysics, Functional Genomics.
- Place of Presentation
  Nago, Japan.
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Oxygen stability and crystal structure of Tetrahymena truncated hemoglobin.2009
- Author(s)
  Igarashi, J., Matsuoka, A.
- Organizer
  14th International Conference on Biological Inorganic Chemistry (ICBIC14).
- Place of Presentation
  Nagoya, Japan.
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Mechanisms of Gas-sensing and Intra-molecular Signal Transduction of a Heme-based Oxygen-sensor Enzyme, Ec DOS2009
- Author(s)
  Atsunari Tanaka, Yukako Ishitsuka, Jotaro Igarashi, Toru Shimizu
- Organizer
  Symposium on Avanced Biological Inorganic Chemistry (SABIC-2009)
- Place of Presentation
  India, Mumbai
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] The Critical Role of the Thiolate-Heme Complex in the Functioning2009
- Author(s)
  Jotaro Igarashi, Kenichi Kitanishi, Motohiko Murase, Marketa Martinkova, Toru Shimizu
- Organizer
  16th International Conference on Cytochrome P450, Biochemistry, Biophysics, Biotechnology
- Place of Presentation
  Japan, Nago, Okinawa
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] Oxygen stability and crystal structure of Tetrahymena truncated hemoglobin2009
- Author(s)
  五十嵐城太郎
- Organizer
  14th International Conference of Biological Inorganic Chemistry
- Place of Presentation
  名古屋
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] ヘム調節インヒビター(HRI)の一酸化窒素による活性調節機構:S-ニトロシル化の検討2009
- Author(s)
  五十嵐城太郎
- Organizer
  第5回日本NO学会学術集会
- Place of Presentation
  静岡
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PUBLICLY-21117501
[Presentation] ヘム調節インヒビター(HRI)の活性調節機構:ヘム結合及びリン酸化について2009
- Author(s)
  五十嵐城太郎, 佐々木健彦, 岩下隼, 清水透
- Organizer
  第82回日本生化学会大会会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] ヘム調節インヒビター(HRI)の-酸化窒素による活性調節機構:S-ニトロシル化の検討2009
- Author(s)
  五十嵐城太郎, 岩下隼, 佐々木健彦, 清水透
- Organizer
  第9回日本NO学会学術集会会
- Place of Presentation
  静岡
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Cysteine thiolate is the heme sensing site in heme-sensor proteins2009
- Author(s)
  Jotaro Igarashi, Kenichi Kitanishi, Toru Shimizu
- Organizer
  XXII International Conference on Coordination and Bioinorganic Chemistry
- Place of Presentation
  Slovakia, Smolenice
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] The heme-binding site of the heme-regulated inhibitor(HRI), and the role of the heme regulatory motif in heme sensing2009
- Author(s)
  五十嵐城太郎
- Organizer
  16th International Conference on Cytochrome P450
- Place of Presentation
  名護
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Molecular mechanism of HRI : Heme binding and autophosphorylation2009
- Author(s)
  五十嵐城太郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21770130
[Presentation] Heme-sensing Mechanisms of Heme-sensor Proteins Associated with Protein Synthesis and Circadian Rhythms2009
- Author(s)
  Jotaro Igarashi, Motohiko Murase, Marketa Martinkova, Kenichi Kitanishi, Toru Shimizu
- Organizer
  14th International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Japan, Nagoya
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] Elucidation of the heme-binding site of heme-regualted eIF2a kinase (H RI) and the role of the regulatory motif in heme sensing by spectroscop ic and catalytic studies of mutant proteins2008
- Author(s)
  Jotaro Igarashi
- Organizer
  Gordon Research Conference on the Chemistry an d Biology of Tetrapyrroles
- Place of Presentation
  Newport, RI, USA
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] NO-induced activation of a heme-sensor, eIF2α kinase, in association with binding to cysteine and heme2008
- Author(s)
  Jotaro Igarashi, Motohiko Murase, Jun Iwashita, Takehiko Sasaki, Toru Shimizu
- Organizer
  Fifth International Conference, Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Austria, Bregenz
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] Identification of the heme axial ligand of HRI : Role of heme regulator motifs2008
- Author(s)
  Jotaro Igarashi
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Elucidation of the heme-binding site of heme-regualted eIF2α kinase (HRI) and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins2008
- Author(s)
  Jotaro Igarashi, Motohiko Murase, Aya Iizuka, Fabio Pichierri, Marketa Martinkova, Toru Shimizu
- Organizer
  Gordon Research Conference on the Chemistry and Biology of Tetrapyrroles
- Place of Presentation
  Newport, RI, U. S. A.
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Identification of the heme axial ligand of HRI : Role of heme regulator motifs2008
- Author(s)
  Jotaro Igarashi, Motohiko Murase, Toru Shimizu
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Identification of a heme axial ligand of heme-regulated eukaryotic initiation factor 2α kinase (HRI) : Role of the Cys-Pro motif in heme regulation2007
- Author(s)
  Jotaro Igarashi, Aya Iizuka, Motohiko Murase, Marketa Martinkova, Toru Shimizu
- Organizer
  13th International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Vienna, Austria
- Year and Date
  2007-07-17
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Identification of a heme axial ligand of heme-regulated eukaryotic initiation factor 2 alpha kinase (HRI): Role of the Cys-Pro motif in heme regulation2007
- Author(s)
  Jotaro Igarashi
- Organizer
  13th International Conference on Biological Inorganic Chemistry
- Place of Presentation
  ウィーン、オーストリア
- Year and Date
  2007-07-17
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] 神経型NO合成酵素に対するアイソザイム選択的阻害剤の構造基盤2007
- Author(s)
  五十嵐城太郎, 他
- Organizer
  第7回日本NO学会学術集会
- Place of Presentation
  大津市
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] Identification of a heme axial ligand of heme-regulated eukaryotic….2007
- Author(s)
  五十嵐城太郎, 他
- Organizer
  13th International Conference on Biological Inorganic Chemistry
- Place of Presentation
  Vienna, Austria
- Year and Date
  2007-07-15
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] Identification of the heme axial ligand, Cys, of HRI: Role of heme regulatory motifs2007
- Author(s)
  五十嵐城太郎
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Structure-function relationships of a thiol-coordinating heme protein, HRI, associated with protein synthesis2007
- Author(s)
  Marketa Martinkova, Jotaro Igarashi, Toru Shimizu
- Organizer
  15th International Conference on Cytochrome P450, Biochemistry, Biophysics, Functional Genomics
- Place of Presentation
  Slovenia, Bled
- Data Source
  KAKENHI-PROJECT-17101002
[Presentation] Oxygen stability and crystal structure of Tetrahymena truncated hemoglobin2007
- Author(s)
  Jotaro Igarashi, Ariki Matsuoka, Tom Shimizu
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-23
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Identification of the heme axial ligand, Cys, of HRI : Role of heme regulatory motifs2007
- Author(s)
  Jotaro Igarashi, Motohiko Murase, Aya Iizuka, Marketa Miksanova, Toru Shimizu
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Oxygen stability and crystal structure of Tetrahymena truncated hemoglobin2007
- Author(s)
  五十嵐城太郎
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-12-23
- Data Source
  KAKENHI-PROJECT-19770099
[Presentation] Role of the N-terminal Domain in the Structure and Catalysis of Heme-regualted Eukaryotic Initiation Factor 2α Kinase, a Heme-sensor Enzyme2006
- Author(s)
  Marketa Miksanova, Hirofumi Kurokawa, Jotaro Igarashi, Toru Shimizu
- Organizer
  Biochemistry and Molecular Biology of Sensor Enzymes and Proteins : Satellite Meeting of the 20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Japan, Sendai
- Data Source
  KAKENHI-PROJECT-17101002

1. SHIMIZU Toru (40118956)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. KUROKAWA Hirofumi (80359546)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. 佐上郁子 (10143033)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TANAKA Atsunari (20431471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 松井敏高 (90323120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Igarashi Jotaro 五十嵐 城太郎

IGARASHI Jotaro 五十嵐 城太郎

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Molecular mechanism of heme-regulated inhibitor (HRI) under stress conditionsPrincipal Investigator

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ＯＧＦＯＤ１による翻訳開始因子キナーゼの水酸化Principal Investigator

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翻訳開始因子キナーゼにおける活性酸素シグナル伝達機構の解明Principal Investigator

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The role of heme-binding, phosphorylation, and degradation in heme-regulated eukaryotic initiation factor 2α kinase (HRI)Principal Investigator

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Interaction of heme and nitric oxide with heme-regulated inhibitor (HRI)Principal Investigator

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Destruction of the biological clock system by environmental contaminants : Crosstalk between heme, NO, protein synthesis and clock genes

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Analyses of Porphyria Caused by Environmental Pollutants : Concerted Reaction and Tempo of Heme and Porphyrin Syntheses

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Construction of Environmental Biremediation Enzymes Whose Catalysis is Regulated by Light and Molecular Switches

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[Book] Gas Sensors : Developments, Efficacy and Safety2011

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[Book] Handbook of Porphyrin Science Vol 152011

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[Book] Handbook of Porphyrin Science Vol.152011

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[Book] Emerging Role of Heme as a Signal and the Gas-Sensing Site : Heme-Sensing and Gas-Sensing Proteins.Handbook of Porphyrin Science (Kadish, K.M., Smith, K.M., Guilard, R.Eds.)2011

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[Book] Circadian Rhythms : Biology, Cognition and Disorders2011

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[Book] 酵素利用技術体系(小宮山眞編)(シトクロムP450.)2010

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[Book] 酵素利用技術体系2010

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Igarashi Jotaro 五十嵐城太郎

IGARASHI Jotaro 五十嵐城太郎

[Book] の分子生物学第2版(大村恒雄, 石村巽, 藤井義明編)(のヘムーチオレート蛋白質の構造と機能.P450)2009