Matsumoto Mitsuyo 松本光代

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MATSUMOTO Mitsuyo 松本光代

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Researcher Number	80400448
Other IDs
Affiliation (Current)	2025: 東北大学, 多元物質科学研究所, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 東北大学, 多元物質科学研究所, 助教 2023: 東北大学, 医学系研究科, 大学院非常勤講師 2015 – 2022: 東北大学, 医学系研究科, 助教 2012: 東北大学, 東北メディカル・メガバンク機構, 助教 2010 – 2011: 東北大学, 大学院・医学系研究科, 助教 2008 – 2009: Tohoku University, 大学院・医学系研究科, 非常勤講師 2007: Tohoku University, 大学院・医学系研究科, 技術補佐員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Tumor biology / Obstetrics and gynecology Except Principal Investigator Medium-sized Section 48:Biomedical structure and function and related fields / General medical chemistry
Keywords	Principal Investigator BACH1 / EMT / 膵臓癌 / Bach1 / 鉄 / フェロトーシス / Pancreatic cancer / Feroptosis / Cancer / RAS … More / Ferroptosis / がん制御遺伝子 / 線維芽細胞 / 癌 / がん微小環境 / がん微小環 / 癌細胞-間質細胞相互作用 / マイクロアレイ / 乳がん / 臨床検体 / ERE活性 / エストロゲン / 乳癌 / 子宮体癌 … More Except Principal Investigator エピジェネティクス / 転写因子 / 頭頸部癌 / 乳癌 / 膵癌 / コンディショナルノックダウン / DNAメチル化 / ヒストンメチル化 / SAM合成酵素 Less

転写因子BACH1と鉄による膵臓癌上皮間葉転換と幹細胞性の促進機構の解明Principal Investigator
- Principal Investigator
  
  松本光代
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tohoku University
Development of anti-cancer strategy by exploiting BACH1 addiction
- Principal Investigator
  
  五十嵐和彦
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Tohoku University
The study of malignant transformation and vulnerability of mutated-RAS carcinomas defined by epithelial-mesenchymal transition and susceptibility to ferroptosisPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Mitsuyo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tohoku University
The effect of BACH1 on malignant transformation of tumorPrincipal Investigator
- Principal Investigator
  
  Matsumoto Mitsuyo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Methods rewriting epigenome as the target of methyonine adenosyltransferase II
- Principal Investigator
  
  KATOH Yasutake
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
The investigation of function of repressor Bach1 in microenvironment of the tumor and the application to a mouse model for cancer stem cell transplantation.Principal Investigator
- Principal Investigator
  
  MATSUMOTO Mitsuyo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Estrogen signaling ability in human endometrial cancer and breastcancer through the cancer-stromal interaction.Principal Investigator
- Principal Investigator
  
  MATSUMOTO Mitsuyo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University

[Book] Metabolism and Epigenetic Regulation: Implications in Cancer: Chapter 2 Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis?2022
- Author(s)
  Igarashi Kazuhiko、Nishizawa Hironari、Matsumoto Mitsuyo
- Total Pages
  14
- Publisher
  Subcell Biochem
- ISBN
  9783031076336
- Data Source
  KAKENHI-PROJECT-23K24156
[Journal Article] TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO222024
- Author(s)
  Liu Liang、Matsumoto Mitsuyo、Watanabe-Matsui Miki、Nakagawa Tadashi、Nagasawa Yuko、Pang Jingyao、Callens Bert K. K.、Muto Akihiko、Ochiai Kyoko、Takekawa Hirotaka、Alam Mahabub、Nishizawa Hironari、Shirouzu Mikako、Shima Hiroki、Nakayama Keiko、Igarashi Kazuhiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 8 Pages: 4141-4141
- DOI
  10.3390/ijms25084141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0176, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-23K24156
[Journal Article] Heme-dependent induction of mitophagy program during differentiation of murine erythroid cells2023
- Author(s)
  Ikeda Masatoshi、Kato Hiroki、Shima Hiroki、Matsumoto Mitsuyo、Furukawa Eijiro、Yan Yan、Liao Ruiqi、Xu Jian、Muto Akihiko、Fujiwara Tohru、Harigae Hideo、Bresnick Emery H.、Igarashi Kazuhiko
- Journal Title
  
  Experimental Hematology
  
  Volume: 118 Pages: 21-30
- DOI
  10.1016/j.exphem.2022.11.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07129, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-21K20770, KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16295, KAKENHI-PROJECT-23K24156
[Journal Article] Ferroptosis model system by the re-expression of BACH12023
- Author(s)
  Irikura Riko、Nishizawa Hironari、Nakajima Kazuma、Yamanaka Mie、Chen Guan、Tanaka Kozo、Onodera Masafumi、Matsumoto Mitsuyo、Igarashi Kazuhiko
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 174 Issue: 3 Pages: 239-252
- DOI
  10.1093/jb/mvad036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14556, KAKENHI-PROJECT-20KK0176, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-23K23877, KAKENHI-PROJECT-23K24156
[Journal Article] mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine2022
- Author(s)
  Alam Mahabub、Shima Hiroki、Matsuo Yoshitaka、Long Nguyen Chi、Matsumoto Mitsuyo、Ishii Yusho、Sato Nichika、Sugiyama Takato、Nobuta Risa、Hashimoto Satoshi、Liu Liang、Kaneko Mika K.、Kato Yukinari、Inada Toshifumi、Igarashi Kazuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 7 Pages: 102084-102084
- DOI
  10.1016/j.jbc.2022.102084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-23K24156
[Journal Article] BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin.2022
- Author(s)
  Liu, L., Matsumoto M., Matsui-Watanabe, M., Ochiai, K., Callens, B.K.K., Nguyen,. L.C., Kozuki, Y., Tanaka, M., Nishizawa, H. and Igarashi, K.
- Journal Title
  
  Antioxidants (Basel)
  
  Volume: 11 Issue: 8 Pages: 1460-1460
- DOI
  10.3390/antiox11081460
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0176, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-23K24156
[Journal Article] Harnessing the Therapeutic Potential of the Nrf2/Bach1 Signaling Pathway in Parkinson’s Disease2022
- Author(s)
  Ahuja Manuj、Kaidery Navneet Ammal、Dutta Debashis、Attucks Otis C.、Kazakov Eliot H.、Gazaryan Irina、Matsumoto Mitsuyo、Igarashi Kazuhiko、Sharma Sudarshana M.、Thomas Bobby
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 9 Pages: 1780-1780
- DOI
  10.3390/antiox11091780
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24156
[Journal Article] The transcription factor BACH1 at the crossroads of cancer biology: From epithelial mesenchymal transition to ferroptosis2021
- Author(s)
  Igarashi Kazuhiko、Nishizawa Hironari、Saiki Yuriko、Matsumoto Mitsuyo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 297 Issue: 3 Pages: 101032-101032
- DOI
  10.1016/j.jbc.2021.101032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07680, KAKENHI-PROJECT-20K16296
[Journal Article] Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells2021
- Author(s)
  Nishizawa Hironari、Matsumoto Mitsuyo、Chen Guan、Ishii Yusho、Tada Keisuke、Onodera Masafumi、Kato Hiroki、Muto Akihiko、Tanaka Kozo、Igarashi Kazuhiko
- Journal Title
  
  Cell Death & Disease
  
  Volume: 12 Issue: 4 Pages: 332-332
- DOI
  10.1038/s41419-021-03613-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16296, KAKENHI-PROJECT-18H02434, KAKENHI-PROJECT-19K23738, KAKENHI-PROJECT-19K07680
[Journal Article] BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition2020
- Author(s)
  Sato Masaki、Matsumoto Mitsuyo、Saiki Yuriko、Alam Mahabub、Nishizawa Hironari、Rokugo Masahiro、Brydun Andrey、Yamada Shinji、Kaneko Mika K.、Funayama Ryo、Ito Mamoru、Kato Yukinari、Nakayama Keiko、Unno Michiaki、Igarashi Kazuhiko
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 6 Pages: 1279-1292
- DOI
  10.1158/0008-5472.can-18-4099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16H05410, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-19K07680
[Journal Article] Bach1 promotes muscle regeneration through repressing Smad-mediated inhibition of myoblast differentiation2020
- Author(s)
  Katsushi Suzuki, Mitsuyo Matsumoto, Yasutake Katoh, Liang Liu, Kyoko Ochiai, Yuta Aizawa, Ryoichi Nagatomi, Hiroshi Okuno, Eiji Itoi, Kazuhiko Igarashi
- Journal Title
  
  PLoS One
  
  Volume: 15(8) Issue: 8 Pages: e0236781-e0236781
- DOI
  10.1371/journal.pone.0236781
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-19K07680
[Journal Article] Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH12019
- Author(s)
  Nishizawa Hironari、Matsumoto Mitsuyo、Shindo Tomohiko、Saigusa Daisuke、Kato Hiroki、Suzuki Katsushi、Sato Masaki、Ishii Yusho、Shimokawa Hiroaki、Igarashi Kazuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 1 Pages: 69-82
- DOI
  10.1074/jbc.ra119.009548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-19K23738, KAKENHI-PROJECT-19K07680
[Journal Article] Infection perturbs Bach2- and Bach1-dependent erythroid lineage chioce to cause anemia2018
- Author(s)
  Kato H, Itoh-Nakadai A, Matsumoto M, Ishii Y, Watanabe-Matsui M, Ikeda M, Ebina-Shibuya R, Sato Y, Kobayashi M, Nishizawa H, Suzuki K, Muto A, Fujiwara T, Nannya Y, Cazzola M, Ogawa S, Harigae H, Igarashi K
- Journal Title
  
  Nat Immunol
  
  Volume: 19 Issue: 10 Pages: 496-497
- DOI
  10.1038/s41590-018-0202-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-16K08572
[Journal Article] Bach2 Promotes B Cell Receptor?Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors2018
- Author(s)
  Miura Yuichi、Morooka Mizuho、Sax Nicolas、Roychoudhuri Rahul、Itoh-Nakadai Ari、Brydun Andrey、Funayama Ryo、Nakayama Keiko、Satomi Susumu、Matsumoto Mitsuyo、Igarashi Kazuhiko、Muto Akihiko
- Journal Title
  
  J Immunol
  
  Volume: - Issue: 8 Pages: 2882-2893
- DOI
  10.4049/jimmunol.1601863
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572
[Journal Article] Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.2018
- Author(s)
  Li J, Shima H, Nishizawa H, Ikeda M, Brydun A, Matsumoto M, Kato H, Saiki Y, Liu L, Watanabe-Matsui M, Iemura K, Tanaka K, Shiraki T, Igarashi K.
- Journal Title
  
  Biochemical Journal
  
  Volume: 475 Issue: 5 Pages: 981-1002
- DOI
  10.1042/bcj20170520
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08573, KAKENHI-PUBLICLY-16H01296, KAKENHI-PROJECT-15H04368, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-16K14604, KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-18H04021
[Journal Article] A Bach2-Cebp gene regulatory network for the commitment of multipotent hematopoietic progenitors.2017
- Author(s)
  Itoh-Nakadai, A., Matsumoto, M., Kato, H., Sasaki, J., Uehara, Y., Sato, Y., Ebina-Shibuya, R., Morooka, M., Funayama, R., Nakayama, K., Ochiai, K., Muto, A. and Igarashi, K.
- Journal Title
  
  Cell Reports
  
  Volume: 18 Issue: 10 Pages: 2401-2414
- DOI
  10.1016/j.celrep.2017.02.029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18998, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-15KK0328
[Journal Article] The mTOR-Bach2 Cascade Controls Cell Cycle and Class Switch Recombination during B Cell Differentiation.2017
- Author(s)
  Tamahara T, Ochiai K, Muto A, Kato Y, Sax N, Matsumoto M, Koseki T, Igarashi K.
- Journal Title
  
  Molecular and cellular biology
  
  Volume: 37 Issue: 24
- DOI
  10.1128/mcb.00418-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07108, KAKENHI-PUBLICLY-16H01295, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15K15771
[Journal Article] Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis.2017
- Author(s)
  Ebina-Shibuya R, Matsumoto M, Kuwahara M, Jang KJ, Sugai M, Ito Y, Funayama R, Nakayama K, Sato Y, Ishii N, Okamura Y, Kinoshita K, Kometani K, Kurosaki T, Muto A, Ichinose M, Yamashita M, Igarashi K.
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 292 Issue: 44 Pages: 18098-18112
- DOI
  10.1074/jbc.m117.808535
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K15232, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04742, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-16H05307, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-16H06640, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15508, KAKENHI-PROJECT-16K19158
[Journal Article] Methionine Adenosyltransferase II-dependent Histone H3K9 Methylation at the COX-2 Gene Locus2013
- Author(s)
  Kera Y, Katoh Y, Ohta M, Matsumoto M, Takano-Yamamoto T, Igarashi K
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 13592-13601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700869
[Journal Article] Methionine adenosyltransferase II-dependent histone H3K9 methylation at the COX-2 gene locus.2013
- Author(s)
  Kera, Y., Katoh, Y., Ohta, M., Matsumoto, M., Takano-Yamamoto, T. and Igarashi, K.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 19 Pages: 12592-13601
- DOI
  10.1074/jbc.m112.429738
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-23249085, KAKENHI-PROJECT-23790321, KAKENHI-PROJECT-25460351
[Journal Article] Solution structure of clostridial collagenase H and its calcium-dependent global conformation change2013
- Author(s)
  Ohbayashi N, Matsumoto T, Shima H, Got o M, Watanabe K, Yamano A, Kato Y, Igarashi K, Yamagata Y, Murayama K
- Journal Title
  
  Biophysical Journal
  
  Volume: 104 Issue: 7 Pages: 1538-1545
- DOI
  10.1016/j.bpj.2013.02.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390310, KAKENHI-PROJECT-23790321, KAKENHI-PROJECT-25460351
[Journal Article] Individual Transcriptional Activity of Estrogen Receptors in Primary Breast Cancer and Its Clinical Significance2012
- Author(s)
  Gohno T, Seino Y, Hanamura T, Niwa T, Matsumoto M, Yaegashi N, Oba H, Kurosumi M, Takei H, Yamaguchi Y, Hayashi S
- Journal Title
  
  Cancer Medicine
  
  Volume: 1 Pages: 328-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700869
[Journal Article] Bach1 is critical for the transformation of mouse embryonic fibroblast by RasV12 and maintains ERK signaling2012
- Author(s)
  Nakanome A, Brydoun A, Matsumoto M, Ota K, Funayama R, Nakayama K, Ono M, Shiga K, Kobayashi T, Igarashi K
- Journal Title
  
  Oncogene
  
  Volume: 32 Issue: 27 Pages: 3231-3245
- DOI
  10.1038/onc.2012.336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700869, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-23659791, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24700951
[Journal Article] Local biosynthesis of estrogen in human endometrial carcinoma through tumor-stromal cell interactions.2009
- Author(s)
  akahashi-Shiga N, Utsunomiya H, Miki Y, Nagase S, Kobayashi R, Matsumoto M, Niikura H, Ito K, Yaegashi N
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages: 6028-6034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791132
[Journal Article] 3-Dimentional Microarray Analysis of Estrogen Signal-related Genes in Breast Cancer Tissues.2009
- Author(s)
  Matsumoto M Sakamoto H, Yamaguchi Y, Seino Y, Takei H, Kurosumi M, Sasano H, Yaegashi N, Hayashi S
- Journal Title
  
  Anti-cancer Research 29
  
  Pages: 3971-3976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791132
[Journal Article] 3-Dimentional Microarray Analysis of Estrogen Signal-related Genes in Breast Cancer Tissues2009
- Author(s)
  Matsumoto Mitsuyo
- Journal Title
  
  Anti-cancer Research 29
  
  Pages: 3971-3976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791132
[Journal Article] The expression of retinoic acid receptors in human endometrial carcinoma.2008
- Author(s)
  Tanabe K, Utsunomiya H, Tamura M, Niikura H, Takano T, Yoshinaga K, Nagase S, Suzuki T, Ito K, Matsumoto M, Hayashi S, Yaegashi N
- Journal Title
  
  Cancer Science 99
  
  Pages: 267-271
- NAID
  10024002120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791132
[Journal Article] Estrogen signaling ability in human endometrial cancer through the cancer-stromal interaction2008
- Author(s)
  Mitsuyo Matsumoto
- Journal Title
  
  Endocrine-Related Cancer 15
  
  Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791132
[Journal Article] Estrogen signaling ability in human endometrial cancer through the cancer-stromal interaction.2008
- Author(s)
  Matsumoto M, Yamaguchi Y, Seino Y, Hatakeyama A, Takei H, Niikura H, Ito K, Suzuki T, Sasano H, Yaegashi N, Hayashi S
- Journal Title
  
  Endocrine-Related Cancer 15
  
  Pages: 451-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791132
[Journal Article] Midkine and its clinical significance in endometrial cancer.2008
- Author(s)
  Tanabe K, Matsumoto M, Ikematsu S, Nagase S, Hatakeyama A, Takano T, Niikura H, Ito K, Kadomatsu K, Hayashi S, Yaegashi N
- Journal Title
  
  Cancer Science 99
  
  Pages: 1125-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791132
[Patent] 新規膵臓癌上皮間葉移行マーカー2019
- Inventor(s)
  五十嵐和彦、松本光代、佐藤正規、西澤弘成
- Industrial Property Rights Holder
  五十嵐和彦、松本光代、佐藤正規、西澤弘成
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-16K07108
[Presentation] BACH1を標的とした高効率触媒的RNA切断機能付与型人工核酸 (CANA) による膵臓癌治療薬開発 IV　-ジャンクション部位の複合体安定性・切断効率への影響-2024
- Author(s)
  五十嵐優希、堀内結翔、松本光代、三瓶悠、西嶋政樹、荒木保幸、山吉麻子、五十嵐和彦、和田健彦
- Organizer
  日本化学会　第104春季年会
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] 癌細胞選択的薬物導入システムの構築と機能評価III: 膵臓癌悪性化抑制薬剤導入を目指して2024
- Author(s)
  加藤ひらり、東亮太、荒木保幸、西嶋政樹、松本光代、中瀬生彦、大村美香、山吉麻子、五十嵐和彦、和田健彦
- Organizer
  日本化学会　第104春季年会
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] B細胞におけるBACH転写因子の量比による転写調節機構の解明2023
- Author(s)
  倉澤岳志、武藤哲彦、松本光代、落合恭子、村山和隆、五十嵐和彦
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20KK0176
[Presentation] TBK1-BACH1軸による膵臓癌細胞上皮間葉転換機構の解明2022
- Author(s)
  松本光代、劉　亮、田中美帆、島　弘季、五十嵐和彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] 転写因子BACH2によるB細胞免疫応答における鉄代謝調節機構2022
- Author(s)
  倉澤岳志、武藤哲彦、松本光代、落合恭子、五十嵐和彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] Attenuation of progressive Alzheimer's disease-like pathology by pharmacologic inhibition and genetic deletion of Bach1 in the APP/PS1 mouse2022
- Author(s)
  Debashis Dutta, Christopher Ye In Kwon, Manuj Ahuja, Navneet Ammal Kaidery, Joyce Meints, Otis C Attucks, Carmen Valcarce, Sudarshana Sharma, Mitsuyo Matsumoto, Kazuhiko Igarashi, Michael K Lee, Bobby Thomas
- Organizer
  International Society for Molecular Neurodegeneration
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] Mechanistic connection of ferroptosis and cancer cell metastasis involving BACH12022
- Author(s)
  Kazuhiko Igarashi , Hironari Nishizawa, Liang Liu , Mitsuyo Matsumoto
- Organizer
  Cold Spring Harbor Asia Meeting: Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] BACH1による膵臓癌細胞の細胞内自由鉄の増加は上皮間葉移行に影響する2022
- Author(s)
  松本光代、五十嵐和彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] 頭頸部癌細胞における転写因子BACH1の細胞死回避機構の解明2022
- Author(s)
  遠藤緋理、松本光代、六郷正博、落合恭子、西澤弘成、五十嵐和彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24156
[Presentation] Regulation of heterogeneity and metastasis of pancreatic cancer cells by the BACH1 gene regulatory network2021
- Author(s)
  Kazuhiko Igarashi, Hironari Nishizawa, Mitsuyo Matsumoto
- Organizer
  日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20KK0176
[Presentation] 膵癌におけるBACH1の機能2019
- Author(s)
  佐藤正規、大塚英郎、松本光代、斎木由利子、三浦孝之、有明恭平、益田邦洋、林洋毅、森川孝則、中川圭、元井冬彦、内藤剛、石田孝宣、亀井尚、五十嵐和彦、海野倫明
- Organizer
  第119回日本外科学会総会
- Data Source
  KAKENHI-PROJECT-19K07680
[Presentation] BACH1 promotes epithelial-mesenchymal transitoin and metastasis in pancreatic cancer through repressing epithelial genes2019
- Author(s)
  Mitsuyo Matsumoto, Masaki Sato, Yuriko Saiki, Hironari Nishizawa, Andrey Brydun, Shinji Yamada, Mika Kaneko, Ryo Funayama, Yukinari Kato, Keiko Nakayama, Michiaki Unno and Kazuhiko Igarashi
- Organizer
  「Tohoku University Thematic Forum for Creativity」 Cancer - from Biology to Acceptance -
- Data Source
  KAKENHI-PROJECT-19K07680
[Presentation] 転写因子Bach1による酸化ストレス依存メラノーマ細胞増殖抑制機序2017
- Author(s)
  松本光代、ブリドンアンドレイ、熊谷さやか、五十嵐和彦
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K07108
[Presentation] メチオニンアデノシル転移酵素（MATII）によるエピジェネティックなCOX-2遺伝子発現制御機構2013
- Author(s)
  解良洋平、加藤恭丈、太田嶺人、松本光代、山本ー高野照子、五十嵐和彦
- Organizer
  第７回日本エピジェネティクス研究会年会
- Place of Presentation
  奈良県新公会堂
- Data Source
  KAKENHI-PROJECT-25460351
[Presentation] Bach1-mediated repression of Pparγ suppresses adipocyte differentiation of fibroblasts in vitro2012
- Author(s)
  松本　光代
- Organizer
  第35回分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22700869
[Presentation] Bach1の繊維芽細胞におけるPparg遺伝子発現制御を介した脂肪分化誘導2012
- Author(s)
  松本光代、ブリドンアンドレイ、舟山亮、西田有一郎、中山啓子、八重樫伸生、五十嵐和彦
- Organizer
  第35回分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22700869
[Presentation] The Genome-Wide Identification of Direct Target Genes of Transcription Factor Bach12011
- Author(s)
  松本光代
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22700869
[Presentation] Bach1の転写制御標的遺伝子の同定2011
- Author(s)
  松本光代、ブリドンアンドレイ、中目亜矢子、舟山亮、西田有一郎、中山啓子、八重樫伸生、五十嵐和彦
- Organizer
  第34回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22700869
[Presentation] ERE-GFPアッセイによる原発性乳癌のエストロゲン受容体転写活性の解析と臨床病理学的因子との関連2009
- Author(s)
  松本光代
- Organizer
  第4回特定非営利活動法人東北内分泌研究会総会
- Place of Presentation
  仙台・艮陵会館
- Year and Date
  2009-04-26
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] Analysis of transcriptional activity of estrogen receptor by ERE-GFP assay in primary breast cancer and its clinical significance2009
- Author(s)
  松本光代
- Organizer
  67th Annual Meeting of the Japanease Cancer-Association
- Place of Presentation
  愛知・名古屋国際会議場
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] 子宮体癌間質細胞におけるエストロゲンを介した相互作用の解析2009
- Author(s)
  松本光代
- Organizer
  第60回日本産婦人科学会
- Place of Presentation
  神奈川・パシフィコ横浜
- Year and Date
  2009-04-15
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] ERE-GFPアッセイを用いた原発性乳癌のエストロゲン受容体転写活性解析と臨床病理学的因子との関連2009
- Author(s)
  松本光代
- Organizer
  第9回ホルモンと癌研究会
- Place of Presentation
  岐阜・長良川国際会議場
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] Tumor-stromal Interaction through Estrogen-Signaling Pathway Analyzed by GFP Assay in Human Endometrial Cancer2009
- Author(s)
  松本光代
- Organizer
  癌研究に係る特定領域研究若手研究者ワークショップ
- Place of Presentation
  長野・アートランドホテル蓼科
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] Analysis of transcriptional activity of estrogen receptor by ERE-GFP assay in primary breast cancer and its clinical significance2008
- Author(s)
  松本光代
- Organizer
  67^<th> Annual Meeting of the Japanease Cancer-Association
- Place of Presentation
  愛知・名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] Expression of midkine in human endometrium and its disorder2008
- Author(s)
  田辺康次郎、松本光代
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2008-10-05
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] Development of diagnosis and therapy for hormone-dependent cancers targeting nuclear receptor2008
- Author(s)
  林慎一、松本光代
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2008-10-05
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] 子宮体癌におけるエストロゲンシグナルを介した癌微小環境の解析2008
- Author(s)
  松本光代
- Organizer
  第8回ホルモンと癌研究会
- Place of Presentation
  東京・品川プリンスホテル
- Year and Date
  2008-07-27
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] ヒト子宮体癌におけるエストロゲン刺激を介した癌-間質の相互作用の解析2008
- Author(s)
  松本光代
- Organizer
  第15回日本ステロイドホルモン学会学術集会
- Place of Presentation
  仙台・艮陵会館
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] umor-stromal interaction through estrogen-signaling pathway analyzed by GFP assay in human endometrial cancer2008
- Author(s)
  松本光代
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2008-10-05
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] 子宮体癌間質細胞におけるエストロゲンを介した相互作用の解析2008
- Author(s)
  松本光代
- Organizer
  第60回日本産婦人科学会
- Place of Presentation
  神奈川・パシフイコ横浜
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] Tumor-stromal interaction through estrogen-signaling pathway analyzed by GFP assay in human endometrial cancer2007
- Author(s)
  松本光代
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19791132
[Presentation] 子宮体癌の微小環境におけるエストロゲン受容体活性化の解析2007
- Author(s)
  松本光代
- Organizer
  第2回特定非営利活動法人東北内分泌研究会総会
- Place of Presentation
  仙台・艮陵会館
- Year and Date
  2007-04-28
- Data Source
  KAKENHI-PROJECT-19791132

1. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. KATOH Yasutake (40397914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. MORITA Masanobu (10519094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAGASHIMA Takeshi (80443000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SAIGUSA Daisuke (90545237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 島弘季 (00448268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 落合恭子 (10455785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 西澤弘成 (30846655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. SATO masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 藤原亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 武藤哲彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 舟山亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsumoto Mitsuyo 松本 光代

MATSUMOTO Mitsuyo 松本 光代

Research Projects

Research Products

Co-Researchers

転写因子BACH1と鉄による膵臓癌上皮間葉転換と幹細胞性の促進機構の解明Principal Investigator

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Development of anti-cancer strategy by exploiting BACH1 addiction

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The study of malignant transformation and vulnerability of mutated-RAS carcinomas defined by epithelial-mesenchymal transition and susceptibility to ferroptosisPrincipal Investigator

Principal Investigator

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Review Section

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The effect of BACH1 on malignant transformation of tumorPrincipal Investigator

Principal Investigator

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Methods rewriting epigenome as the target of methyonine adenosyltransferase II

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The investigation of function of repressor Bach1 in microenvironment of the tumor and the application to a mouse model for cancer stem cell transplantation.Principal Investigator

Principal Investigator

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Research Institution

Estrogen signaling ability in human endometrial cancer and breastcancer through the cancer-stromal interaction.Principal Investigator

Principal Investigator

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[Book] Metabolism and Epigenetic Regulation: Implications in Cancer: Chapter 2 Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis?2022

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[Journal Article] TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO222024

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[Journal Article] Heme-dependent induction of mitophagy program during differentiation of murine erythroid cells2023

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[Journal Article] Ferroptosis model system by the re-expression of BACH12023

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[Journal Article] mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine2022

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[Journal Article] BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin.2022

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[Journal Article] Harnessing the Therapeutic Potential of the Nrf2/Bach1 Signaling Pathway in Parkinson’s Disease2022

Author(s)

Matsumoto Mitsuyo 松本光代

MATSUMOTO Mitsuyo 松本光代