Naguro Isao 名黒功

… Alternative Names

NAGURO Isao 名黒功

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Researcher Number	80401222
Other IDs	https://orcid.org/0000-0002-0338-8026
Affiliation (Current)	2025: 順天堂大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 順天堂大学, 薬学部, 教授 2016 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 准教授 2017: 東京大学, 大学院薬学系研究科, 准教授 2012 – 2015: 東京大学, 薬学研究科(研究院), 講師 2013: 東京大学, 大学院薬学系研究科, 講師 … More 2012: 東京大学, 大学院・薬学系研究科, 講師 2011: 東京大学, 薬学研究科(研究院), 助教 2007 – 2011: The University of Tokyo, 大学院・薬学系研究科, 助教 2006: 東京大学, 大学院薬学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Molecular biology / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields Except Principal Investigator Biological pharmacy / Biological Sciences / Functional basic dentistry / Biological Sciences
Keywords	Principal Investigator ASK3 / 浸透圧 / NFAT5 / 浸透圧ストレス / マクロファージ / ストレス応答 / シグナル伝達 / 細胞代謝 / RNAiスクリーニング / キナーゼ … More / MAPK / リン酸化酵素 / 免疫細胞 / 炎症 / Osmonitoring / 遺伝子改変マウス / 脂質分子 / osmo-physiology / 代謝変化 / LLPS / Osmo-physiology / siRNAスクリーニング / ゲノムワイドsiRNAスクリーニング / ASK1 / がん転移 / ハイコンテントアナリシス / RNAi スクリーニング / 高血圧症 / 浸透圧ストレ / 細胞内情報伝達 / ストレス応答性 / 細胞応答 / シングルセル解析 … More Except Principal Investigator ストレス / 小胞体ストレス / ASKファミリー / ASK1 / シグナル伝達 / ミトコンドリアストレス / 浸透圧ストレス / 酸化ストレス / 応答 / 選別 / 小胞輸送 / ゴルジ体 / 超解像顕微鏡 / タンパク質分解 / 輸送 / 小胞体 / オルガネラ・ゾーン / オルガネラ / 線虫 / p38 / PGAM5 / 浸透圧 / アポトーシス / MAPキナーゼ / ALS / 神経細胞死 / Derlin-l / ASEl / 筋萎縮性側索硬化症 Less

体内局所Na環境がマクロファージ細胞を制御する分子機序の解明と病態関与の理解Principal Investigator
- Principal Investigator
  
  名黒功
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Juntendo University
Development of genetically modified mice (Osmonitoring mice) that monitor osmotic environment in the body for an understanding of immune regulationPrincipal Investigator
- Principal Investigator
  
  Naguro Isao
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  The University of Tokyo
Elucidation of multilayered cellular responses to osmotic environment and functions of the response in macrophagesPrincipal Investigator
- Principal Investigator
  
  名黒功
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Elucidation of osmo-physiology through analysis where and how osmotic circumstance functions in the bodyPrincipal Investigator
- Principal Investigator
  
  Naguro Isao
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum
- Principal Investigator
  
  Mori Kazutoshi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Analysis of sensing and responding mechanisms for osmotic stress in mammalian cells(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  NAGURO ISAO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
The regulatory mechanisms of tumor metastasis via ASK family proteinsPrincipal Investigator
- Principal Investigator
  
  Naguro Isao
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
Analysis of sensing and responding mechanisms for osmotic stress in mammalian cellsPrincipal Investigator
- Principal Investigator
  
  Naguro Isao
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
A genome-wide RNAi screening for clarifying the molecular mechanism of osmotic stress response in the mammalian cellPrincipal Investigator
- Principal Investigator
  
  NAGURO Isao
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
Homeostasis Regulation via Stress Signaling and its Molecular Basis for Drug Development
- Principal Investigator
  
  ICHIJO Hidenori
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
The analysis of cellular osmotic stress sensing and response by focusing onASK3Principal Investigator
- Principal Investigator
  
  NAGURO Isao
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Drug development by the molecular mechanism-based analysis of stress signaling
- Principal Investigator
  
  ICHIJO Hidenori
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
口腔疾患に関わるストレスシグナル解明への遺伝学的アプローチ
- Principal Investigator
  
  一條秀憲
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokyo
The analysis of cellular osmotic stress response focusing on a novel kinase ASK3Principal Investigator
- Principal Investigator
  
  NAGURO Isao
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
異常蛋白質蓄積によるASK1シグナルを介した神経変性細胞死の分子病態の解明
- Principal Investigator
  
  NISHITOH Hideki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
浸透圧ストレス応答における新規リン酸化酵素ASK3の活性ヒ機構明と能解析Principal Investigator
- Principal Investigator
  
  名黒功
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

[Book] Advances in BIOLOGICAL REGULATIOＮ2017
- Author(s)
  Guest Editors: Hidenori Ichijo and Isao Naguro
- Total Pages
  90
- Publisher
  ELSEVIER
- ISBN
- Data Source
  KAKENHI-PROJECT-25221302
[Book] Advances in Biological Regulation2017
- Author(s)
  Guest Editors: Hidenori Ichijo and Isao Naguro
- Total Pages
  90
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-15H04643
[Book] Redox Proteins in Supercomplexes and Signalosomes2015
- Author(s)
  Machida, T., Ichijo, H. and Naguro, I.
- Total Pages
  68
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-15K14445
[Book] 実験医学増刊”知る・見る・活かす！シグナリング研究2015”2015
- Author(s)
  名黒　功
- Total Pages
  214
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15H04643
[Book] Annual Review 免疫 20072006
- Author(s)
  名黒功
- Total Pages
  330
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-18890050
[Journal Article] Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation2023
- Author(s)
  Ikizawa Takeshi、Ikeda Kazutaka、Arita Makoto、Kitajima Shojiro、Soga Tomoyoshi、Ichijo Hidenori、Naguro Isao
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 2 Pages: 102837-102837
- DOI
  10.1016/j.jbc.2022.102837
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19324, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-20K07598, KAKENHI-PROJECT-23K24024
[Journal Article] Sodium ion influx regulates liquidity of biomolecular condensates in hyperosmotic stress response2023
- Author(s)
  Morishita Kazuhiro、Watanabe Kengo、Naguro Isao、Ichijo Hidenori
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 4 Pages: 112315-112315
- DOI
  10.1016/j.celrep.2023.112315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21J13845, KAKENHI-PROJECT-22K19324, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-23K24024
[Journal Article] NAMPT-dependent NAD+ salvage is crucial for the decision between apoptotic and necrotic cell death under oxidative stress.2022
- Author(s)
  Takuto Nishida, Isao Naguro and Hidenori Ichijo
- Journal Title
  
  Cell Death Discovery
  
  Volume: 8 Issue: 1 Pages: 195-195
- DOI
  10.1038/s41420-022-01007-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15037, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-23K24024
[Journal Article] The mitochondrial Ca2+ uptake regulator, MICU1, is involved in cold stress‐induced ferroptosis2021
- Author(s)
  Nakamura Toshitaka、Ogawa Motoyuki、Kojima Kazuki、Takayanagi Saki、Ishihara Shunya、Hattori Kazuki、Naguro Isao、Ichijo Hidenori
- Journal Title
  
  EMBO reports
  
  Volume: 22 Issue: 5
- DOI
  10.15252/embr.202051532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-19J22644, KAKENHI-PROJECT-20J14731, KAKENHI-PROJECT-21H04760, KAKENHI-ORGANIZER-17H06413
[Journal Article] FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells2021
- Author(s)
  Ogawa Motoyuki、Kawarazaki Yosuke、Fujita Yasuyuki、Naguro Isao、Ichijo Hidenori
- Journal Title
  
  Current Biology
  
  Volume: 31 Issue: 5 Pages: 1048-1057
- DOI
  10.1016/j.cub.2020.11.052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21411, KAKENHI-PROJECT-18H03994, KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-20J14731, KAKENHI-PROJECT-21H04760
[Journal Article] ASK1 suppresses NK cell-mediated intravascular tumor cell clearance in lung metastasis.2021
- Author(s)
  Fujimoto, M., Kamiyama, M., Fuse, K., Ryuno, H., Odawara, T., Furukawa, N., Yoshimatsu, Y., Watabe, T., Michaela, P.-M., Veronika, S., Tahara, H., Hayakawa, Y., Sato, T., Takeda, K., Naguro, I. and Ichijo, H.
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 4 Pages: 1633-1643
- DOI
  10.1111/cas.14842
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07032, KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-17K07157, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-21K07094, KAKENHI-PROJECT-20H03851
[Journal Article] Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose)2021
- Author(s)
  Watanabe Kengo、Morishita Kazuhiro、Zhou Xiangyu、Shiizaki Shigeru、Uchiyama Yasuo、Koike Masato、Naguro Isao、Ichijo Hidenori
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1353-1353
- DOI
  10.1038/s41467-021-21614-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07743, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-21H04760, KAKENHI-ORGANIZER-17H06413
[Journal Article] Osmotic gradients induce stable dome morphogenesis on extracellular matrix2020
- Author(s)
  Ishida-Ishihara Sumire、Akiyama Masakazu、Furusawa Kazuya、Naguro Isao、Ryuno Hiroki、Sushida Takamichi、Ishihara Seiichiro、Haga Hisashi
- Journal Title
  
  Journal of Cell Science
  
  Volume: 133 Issue: 14 Pages: 243865-243865
- DOI
  10.1242/jcs.243865
- NAID
  120007124455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12793, KAKENHI-PLANNED-15H05857, KAKENHI-PUBLICLY-19H05336, KAKENHI-PROJECT-18H02569
[Journal Article] Genome-wide siRNA screening reveals that DCAF4-mediated ubiquitination of optineurin stimulates autophagic degradation of Cu/Zn superoxide dismutase.2020
- Author(s)
  Homma, K., Takahashi, H., Tsuburaya, N., Naguro, I., Fujisawa, T. and Ichijo, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 295 Issue: 10 Pages: 3148-3158
- DOI
  10.1074/jbc.ra119.010239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15358, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-18H03995
[Journal Article] ASK1 promotes uterine inflammation leading to pathological preterm birth2020
- Author(s)
  Yoshikawa Midori、Iriyama Takayuki、Suzuki Kensuke、Sayama Seisuke、Tsuruga Tetsushi、Kumasawa Keiichi、Nagamatsu Takeshi、Homma Kengo、Naguro Isao、Osuga Yutaka、Ichijo Hidenori、Fujii Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1887-1887
- DOI
  10.1038/s41598-020-58653-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22678, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-18H03995
[Journal Article] Molecular functions of ASK family in diseases caused by stress-induced inflammation and apoptosis2020
- Author(s)
  Kojima Kazuki、Ichijo Hidenori、Naguro Isao
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: in press Issue: 4 Pages: 395-407
- DOI
  10.1093/jb/mvaa145
- NAID
  40022588047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18H02569
[Journal Article] Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases.2019
- Author(s)
  Nakamura, T., Naguro, I. and Ichijo, H.
- Journal Title
  
  Biochim. Biophys. Acta. Gen. Subj.
  
  Volume: pii Issue: 9 Pages: 1398-1409
- DOI
  10.1016/j.bbagen.2019.06.010
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-18H03995
[Journal Article] In situ single-cell western blot on adherent cell culture.2019
- Author(s)
  Zhang, Y., Naguro, I. and Herr, A.
- Journal Title
  
  Angew. Chem. Int. Ed. Engl.
  
  Volume: 58 Issue: 39 Pages: 13929-13934
- DOI
  10.1002/anie.201906920
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H02569
[Journal Article] A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress2018
- Author(s)
  Watanabe Kengo、Umeda Tsuyoshi、Niwa Kuniyoshi、Naguro Isao、Ichijo Hidenori
- Journal Title
  
  Cell Reports
  
  Volume: 22 Issue: 11 Pages: 2809-2817
- DOI
  10.1016/j.celrep.2018.02.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15086, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-18K19469, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-18H03995
[Journal Article] ASK family kinases mediate cellular stress and redox signaling to circadian clock2018
- Author(s)
  Imamura Kiyomichi、Yoshitane Hikari、Hattori Kazuki、Yamaguchi Mitsuo、Yoshida Kento、Okubo Takenori、Naguro Isao、Ichijo Hidenori、Fukada Yoshitaka
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 14 Pages: 3646-3651
- DOI
  10.1073/pnas.1719298115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-16K18872, KAKENHI-PROJECT-18K19469, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-17H06096, KAKENHI-PROJECT-18H03995
[Journal Article] mASKing cancer cells in a tumor microenvironment2018
- Author(s)
  Kamiyama Miki、Naguro, Isao、Ichijo Hidenori
- Journal Title
  
  Cell Cycle
  
  Volume: 17 Issue: 2 Pages: 139-140
- DOI
  10.1080/15384101.2017.1407402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-18K19469, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-18H03995
[Journal Article] β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress2018
- Author(s)
  Cheng Ran、Takeda Kohsuke、Naguro Isao、Hatta Tomohisa、Iemura Shun-ichiro、Natsume Tohru、Ichijo Hidenori、Hattori Kazuki
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1862 Issue: 10 Pages: 2271-2280
- DOI
  10.1016/j.bbagen.2018.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19469, KAKENHI-PUBLICLY-17H05511, KAKENHI-PLANNED-17H06419, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-17K19768, KAKENHI-PROJECT-18H03995
[Journal Article] A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model2018
- Author(s)
  Tsuburaya, N., Homma, K., Higuchi, T., Balia, A., Yamakoshi, H., Shibata, N., Nakamura, S., Nakagawa, H., Ikeda, S., Umezawa, N., Kato, N., Yokoshima, S., Shibuya, M., Shimonishi, M., Kojima, H., Okabe, T., Nagano, T., Naguro, I., Imamura, K., Inoue, H., Fujisawa, T., and Ichijo, H.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 2668-2668
- DOI
  10.1038/s41467-018-05127-2
- NAID
  120006546002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-18K15358, KAKENHI-PLANNED-17H06419, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-16K08172, KAKENHI-PLANNED-26111007, KAKENHI-PROJECT-18H03995
[Journal Article] ASK family and cancer2017
- Author(s)
  Ryuno, H., Naguro, I. and Kamiyama, M.
- Journal Title
  
  Adv. Biol. Regul.
  
  Volume: 66 Pages: 72-84
- DOI
  10.1016/j.jbior.2017.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04643
[Journal Article] TRIM48 promotes ASK1 activation and cell death through ubiquitination-dependent degradation of the ASK1 negative regulator PRMT1.2017
- Author(s)
  Hirata, Y., Katagiri, K., Nagaoka, K., Morishita, T., Kudoh, Y., Hatta, T., Naguro, I., Kano, K., Udagawa, T., Natsume, T., Aoki, J., Inada, T., Noguchi, T., Ichijo, H., Matsuzawa, A.
- Journal Title
  
  Cell Rep.
  
  Volume: 21 Issue: 9 Pages: 2447-2457
- DOI
  10.1016/j.celrep.2017.11.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05518, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-16K15146, KAKENHI-PLANNED-26114009
[Journal Article] Cold stress‐induced ferroptosis involves the ASK1‐p38 pathway2017
- Author(s)
  Hattori Kazuki、Ishikawa Hiroyuki、Sakauchi Chihiro、Takayanagi Saki、Naguro Isao、Ichijo Hidenori
- Journal Title
  
  EMBO reports
  
  Volume: 18 Issue: 11 Pages: 2067-2078
- DOI
  10.15252/embr.201744228
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-16K18872, KAKENHI-PLANNED-26111007, KAKENHI-PLANNED-26114009
[Journal Article] Involvement of apoptosis signal-regulating kinase-1 in house dust miteinduced allergic asthma in mice2017
- Author(s)
  Maruoka, S., Gon, Y., Mizumura, K., Okamoto, S., Tsuya, K., Shikano, S., Soda, K., Naguro, I., Ichijo, H. and Hashimoto, S.
- Journal Title
  
  Allergol. Int.
  
  Volume: 66 Issue: Supplement.1 Pages: S50-S52
- DOI
  10.1016/j.alit.2017.05.007
- NAID
  130006182289
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PLANNED-26114009
[Journal Article] ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.2017
- Author(s)
  Kamiyama, M., Shirai, T., Tamura, S., Suzuki-Inoue, K., Ehata, S., Takahashi, K., Miyazono, K., Hayakawa, Y., Sato, T., Takeda, K., Naguro, I., Ichijo, H.
- Journal Title
  
  Cell Death and Differentiation
  
  Volume: 24 Issue: 12 Pages: 2066-2076
- DOI
  10.1038/cdd.2017.114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19768, KAKENHI-PUBLICLY-17H05511, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-16K15115, KAKENHI-PLANNED-26114009
[Journal Article] KLHDC10 deficiency protects mice against TNFα-induced systemic inflammation.2016
- Author(s)
  Yamaguchi, N., Sekine, S., Naguro, I., Sekine, Y. and Ichijo, H.
- Journal Title
  
  PLOS one
  
  Volume: 11 Issue: 9 Pages: e0163118-e0163118
- DOI
  10.1371/journal.pone.0163118
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-16K15115, KAKENHI-PLANNED-26114009
[Journal Article] ASK1 signaling regulates brown and beige adipocyte maturation2016
- Author(s)
  Kazuki H, Naguro I, Okabe K, Funatsu T, Furutani S, Takeda K, and Ichijo H
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 11158-11158
- DOI
  10.1038/ncomms11158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05931, KAKENHI-PUBLICLY-26107704, KAKENHI-PLANNED-26111007, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-26293016, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-16K18872, KAKENHI-PLANNED-26114009
[Journal Article] The ablation of mitochondrial protein phosphatase pgam5 confers resistance against metabolic stress2016
- Author(s)
  Sekine S., Yao, A., Hattori, K., Sugawara, S., Naguro, I., Koike, M., Uchiyama, Y., Takeda, K., Ichijo, H
- Journal Title
  
  EBioMedicine
  
  Volume: 6 Pages: 82-92
- DOI
  10.1016/j.ebiom.2016.01.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01388, KAKENHI-PLANNED-26111007, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-26293016, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-25221302
[Journal Article] Mitogen-activated protein kinases as key players in osmotic stress signaling.2016
- Author(s)
  Zhou, X., Naguro, I., Ichijo, H. and Watanabe, K.
- Journal Title
  
  Biochem. Biophys. Acta
  
  Volume: 1860 Issue: 9 Pages: 2037-2052
- DOI
  10.1016/j.bbagen.2016.05.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PLANNED-26114009
[Journal Article] Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway.2016
- Author(s)
  Maruyama J, Kobayashi Y, Umeda T, Vandewalle A, Takeda K, Ichijo H, Naguro I.
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 18710-18710
- DOI
  10.1038/srep18710
- NAID
  120006987229
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860185, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-26293016, KAKENHI-PLANNED-26114009
[Journal Article] The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.2016
- Author(s)
  Koizumi S, Irie T, Hirayama S, Sakurai Y, Yashiroda H, Naguro I, Ichijo H, Hamazaki J, Murata S.
- Journal Title
  
  Elife
  
  Volume: 18357 Pages: 18357-18357
- DOI
  10.7554/elife.18357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15J01930, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-16K20998, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-26114009
[Journal Article] A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.2015
- Author(s)
  Fujisawa, T., Yamaguchi, N., Kadowaki, H., Tsukamoto, Y., Tsuburaya, N., Tsubota, A., Takahashi, H., Naguro, I., Takahashi, Y., Goto, J., Tsuji, S., Nishitoh, H., Homma, K. and Ichijo, H.
- Journal Title
  
  Neurobiol. Dis.
  
  Volume: 82 Issue: 2 Pages: 478-486
- DOI
  10.1093/hmg/ddv467
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-13J10826, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-25221302, KAKENHI-PUBLICLY-15H01539, KAKENHI-PROJECT-15H05019, KAKENHI-PROJECT-15K15685
[Journal Article] Regulation of Cellular Signalling by Thioredoxin2015
- Author(s)
  Machida, T., Ichijo, H. and Naguro, I.
- Journal Title
  
  Redox Proteins in Supercomplexes and Signalosomes
  
  Volume: CRC Press Pages: 255-274
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25221302
[Journal Article] Apoptosis Signal-regulating Kinase 1(ASK1)-p38 pathway-dependent cytoplasmic translocation of the orphan nuclear receptor NR4A2 is required for oxidative stress-induced necrosis2015
- Author(s)
  Watanabe T, Sekine S, Naguro I, Sekine Y, Ichijo H.
- Journal Title
  
  J Biol Chem
  
  Volume: in press Issue: 17 Pages: 10791-10803
- DOI
  10.1074/jbc.m114.623280
- NAID
  120007150218
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25650004, KAKENHI-PLANNED-26114009, KAKENHI-PLANNED-26111007, KAKENHI-PROJECT-25221302
[Journal Article] A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.2015
- Author(s)
  Fujisawa T, Yamaguchi N, Kadowaki H, Tsukamoto T, Tsuburaya N, Tsubota A, Takahashi H, Naguro I, Takahashi Y, Goto J, Tsuji S, Nishitoh H, Homma K, Ichijo H
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 82 Pages: 478-486
- DOI
  10.1016/j.nbd.2015.08.010
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11080, KAKENHI-PROJECT-15K15685, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-13J10655, KAKENHI-PLANNED-26114009
[Journal Article] In vivo gene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression2015
- Author(s)
  Kamiyama, M., Naguro, I. and Ichijo, H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Issue: 7 Pages: 785-796
- DOI
  10.1111/cas.12676
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14445, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-13J10846
[Journal Article] Apoptosis Signal-Regulating Kinase 1 (ASK1) as a therapeutic target2014
- Author(s)
  Kawarazaki, Y., Ichijo, H. and Naguro, I.
- Journal Title
  
  Expert Opinion on Therapeutic Targets
  
  Volume: 18 Issue: 6 Pages: 651-664
- DOI
  10.1517/14728222.2014.896903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-25650004, KAKENHI-PLANNED-26114009
[Journal Article] Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses2014
- Author(s)
  Maruyama, T., Araki, T., Kawarazaki, Y., Naguro, I., Heynen, S., Aza-Blanc, P., Ronai, Z., Matsuzawa, A. and Ichijo, H.
- Journal Title
  
  Sci. Signal.
  
  Volume: 7 Issue: 309
- DOI
  10.1126/scisignal.2004822
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-25650004, KAKENHI-PROJECT-25650061, KAKENHI-PROJECT-26293011, KAKENHI-PLANNED-26114009
[Journal Article] The DEAH-Box RNA Helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses2014
- Author(s)
  Mosallanejad, K., Sekine, Y., Ishikura-Kinoshita, S., Kumagai, K., Nagano, T., Matsuzawa, A., Takeda, K., Naguro, I. and Ichijo, H.
- Journal Title
  
  Sci. Signal.
  
  Volume: 7 Issue: 323
- DOI
  10.1126/scisignal.2004841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-25650004, KAKENHI-PROJECT-25650061, KAKENHI-PROJECT-26293011, KAKENHI-PROJECT-26293016, KAKENHI-PLANNED-26114009
[Journal Article] SOD1 as a molecular switch for initiating the homeostatic ER stress respouse under zinc deficiency.2013
- Author(s)
  Homma, K., Fujisawa. T., Tsuburaya, N., Yamaguchi, N., Kadowaki, H., Takeda, K., Nishitoh, H., Matsuzawa, A., Naguro, I., and Ichijo, H.
- Journal Title
  
  Molecular Cell
  
  Volume: 52 Issue: 1 Pages: 75-86
- DOI
  10.1016/j.molcel.2013.08.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10655, KAKENHI-PROJECT-13J10826, KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-24390418, KAKENHI-PROJECT-24659027, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-25650004, KAKENHI-PROJECT-25650061, KAKENHI-PROJECT-25870562
[Journal Article] Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling2013
- Author(s)
  Shiizaki, S., Naguro, I. and Ichijo, H.
- Journal Title
  
  Adv. Biol. Regul.
  
  Volume: 53 Issue: 1 Pages: 135-144
- DOI
  10.1016/j.jbior.2012.09.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-23659033, KAKENHI-PROJECT-23790078
[Journal Article] ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney.2012
- Author(s)
  Naguro I., et al.
- Journal Title
  
  Nature Communications
  
  Volume: 3 Issue: 1 Pages: 1285-1285
- DOI
  10.1038/ncomms2283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J09620, KAKENHI-PROJECT-11J09074, KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-20249047, KAKENHI-PROJECT-22390347, KAKENHI-PROJECT-23390058, KAKENHI-PROJECT-23659033, KAKENHI-PROJECT-23659439, KAKENHI-PROJECT-23790078, KAKENHI-PROJECT-24390418, KAKENHI-PROJECT-24659027, KAKENHI-PUBLICLY-23110504, KAKENHI-PUBLICLY-23117510
[Journal Article] A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants.2012
- Author(s)
  Fujisawa, T., Homma, K., et al.
- Journal Title
  
  Ann Neurol
  
  Volume: 72 Issue: 5 Pages: 739-749
- DOI
  10.1002/ana.23668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J09619, KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-22390347, KAKENHI-PROJECT-23659033, KAKENHI-PROJECT-23790078, KAKENHI-PROJECT-24390418, KAKENHI-PROJECT-24659027, KAKENHI-PUBLICLY-23110504, KAKENHI-PUBLICLY-23117510
[Journal Article] p38 MAP kinase regulates the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors2011
- Author(s)
  Sekine,Y., Takagahara,S., Hatanaka, R., Watanabe, T., Oguchi, H., Noguchi, T., Naguro, I., Kobayashi, K., Tsunoda, M., Funatsu, T., Nomura, H., Toyoda, T., Matsuki, N., Kuranaga, E., Miura, M., Takeda, K., and Ichijo, H.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 124 Issue: 17 Pages: 3006-3016
- DOI
  10.1242/jcs.085902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-22390347, KAKENHI-PROJECT-22890031, KAKENHI-PUBLICLY-23117510, KAKENHI-PROJECT-23659033, KAKENHI-PROJECT-23700367, KAKENHI-PROJECT-23790078
[Journal Article] Apoptosis signaling kinases: from stress response to health outcomes2011
- Author(s)
  Takeda, K., Naguro, I., Nishitoh, H., Matsuzawa, A. and Ichijo, H.
- Journal Title
  
  Antioxid. Redox Signal.
  
  Volume: 15 Issue: 3 Pages: 719-761
- DOI
  10.1089/ars.2010.3392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-20390477, KAKENHI-PUBLICLY-22020007, KAKENHI-PUBLICLY-23110504, KAKENHI-PUBLICLY-23117510
[Journal Article] CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response2010
- Author(s)
  Maruyama, T., Kadowaki, H., Okamoto, N., Nagai, A., Naguro, I., Matsuzawa, A., Shibuya, H., Tanaka, K., Murata, S., Takeda, K., Nishitoh, H. and Ichijo H.
- Journal Title
  
  EMBO J.
  
  Volume: 4 Issue: 15 Pages: 2501-2514
- DOI
  10.1038/emboj.2010.141
- Data Source
  KAKENHI-PROJECT-20229004
[Journal Article] CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.2010
- Author(s)
  Maruyama, T., Kadowaki, H., Okamoto, N., Nagai, A., Naguro. I., Matsuzawa, A., Shibuya, H., Tanaka, K., Murata, S., Takeda, K., Nishitoh, H., Ichijo H.
- Journal Title
  
  EMBO J. 4
  
  Pages: 2501-2514
- Data Source
  KAKENHI-PROJECT-20229004
[Journal Article] The roles of ASK family proteins in stress responses and diseases2009
- Author(s)
  Hattori, K., Naguro, I., Runchel, C. and Ichijo H.
- Journal Title
  
  Cell Communication and Signaling
  
  Volume: 7 Issue: 1 Pages: 9-9
- DOI
  10.1186/1478-811x-7-9
- Data Source
  KAKENHI-PROJECT-20229004
[Journal Article] Stress-Activated MAP Kinase Cascades in Cellular Senescence.2009
- Author(s)
  Maruyama, J., Naguro, I., Takeda, K., Ichijo, H.
- Journal Title
  
  Curr. Med. Chem. 16
  
  Pages: 1229-1235
- Data Source
  KAKENHI-PROJECT-20790058
[Journal Article] ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.2009
- Author(s)
  Iriyama, T., Takeda, K., Nakamura, H.,Morimoto, Y., Kuroiwa, T., Mizukami, J.,Umeda, T., Noguchi, T., Naguro, I., Nishitoh,H., Saegusa, K., Tobiume, K., Homma, T.,Shimada, Y., Tsuda, H., Aiko, S., Imoto, I.,Inazawa, J., Chida, K., Kamei, Y., Kozuma, S.,Taketani, Y., Matsuzawa, A., Ichijo, H
- Journal Title
  
  EMBO J. 28
  
  Pages: 843-853
- Data Source
  KAKENHI-PROJECT-20790058
[Journal Article] Stress-Activated MAP Kinase Cascades in Cellular Senescence2009
- Author(s)
  Maruyama, J., Naguro, I., Takeda, K. and Ichijo H.
- Journal Title
  
  Curr. Med. Chem.
  
  Volume: 16 Issue: 10 Pages: 1229-1235
- DOI
  10.2174/092986709787846613
- Data Source
  KAKENHI-PROJECT-20229004
[Journal Article] ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis2009
- Author(s)
  Iriyama, T., Takeda, K., Nakamura, H., Morimoto, Y., Kuroiwa, T., Mizukami, J., Umeda, T., Noguchi, T., Naguro, I., Nishitoh, H., Saegusa, K., Tobiume, K., Homma, T., Shimada, Y., Tsuda, H., Aiko, S., Imoto, I., Inazawa, J., Chida, K., Kamei, Y., Kozuma, S., Taketani, Y., Matsuzawa, A. and Ichijo H.
- Journal Title
  
  EMBO J.
  
  Volume: 28 Issue: 7 Pages: 843-853
- DOI
  10.1038/emboj.2009.32
- Data Source
  KAKENHI-PROJECT-20229004
[Journal Article] ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.2009
- Author(s)
  Iriyama, T., Takeda, K., Nakamura, H., Morimoto, Y., Kuroiwa, T., Mizukami, J., Umeda, T., Noguchi, T., Naguro, I., Nishitoh, H., Saegusa, K., Tobiume, K., Homma, T., Shimada, Y., Tsuda, H., Aiko, S., Imoto, I., Inazawa, J., Chida, K., Kamei, Y., Kozuma, S., Taketani, Y., Matsuzawa, A., Ichijo, H.
- Journal Title
  
  EMBO J. 28
  
  Pages: 843-853
- Data Source
  KAKENHI-PROJECT-20229004
[Journal Article] The roles of ASK family proteins in stress responses and diseases.2009
- Author(s)
  Hattori, K., Naguro, I., Runchel, C., Ichijo, H.
- Journal Title
  
  Cell Communication and Signaling 7
  
  Pages: 9-9
- Data Source
  KAKENHI-PROJECT-20790058
[Journal Article] Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAP kinase pathway for extracelluler ATP-induced apoptosis in macrophage.2008
- Author(s)
  Noguchi, T., Ishii, K., Fukutomi, H., Naguro, I., Matsuzawa, A., Takeda, K., Ichijo, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 7657-7665
- Data Source
  KAKENHI-PROJECT-20790058
[Journal Article] Apoptosis Signal-regulating Kinase 1 (ASK1) in stress and immune response.2008
- Author(s)
  Takeda, K., Noguchi, T., Naguro, I., Ichijo, H.
- Journal Title
  
  Annu. Rev. Pharmacol. Toxicol. 48
  
  Pages: 199-225
- Data Source
  KAKENHI-PROJECT-20790058
[Journal Article] Apoptosis Signal-regulating Kinase 1(ASK1)in stress and immune response.2008
- Author(s)
  Takeda, K., Noguchi, T., Naguro, I., Ichijo, H.
- Journal Title
  
  Annu. Rev. Pharmacol. Toxicol. 48
  
  Pages: 199-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023013
[Journal Article] Apoptosis Signal-regulating Kinase 1 (ASK1) in stress and immune response2008
- Author(s)
  Takeda, K., Noguchi, T., Naguro, I. and Ichijo H.
- Journal Title
  
  Annu.Rev. Pharmacol.Toxicol.
  
  Volume: 48 Issue: 1 Pages: 199-225
- DOI
  10.1146/annurev.pharmtox.48.113006.094606
- Data Source
  KAKENHI-PROJECT-20229004
[Journal Article] Apoptosis signal-regulating kinase2(ASK2)functions as a MAP3K in a heteromeric complex with ASK1.2007
- Author(s)
  Takeda, K., Shimozono, R., Noguchi, T., Umeda, T., Morimoto, Y., Naguro, I., Tobiume, K., Saitoh, M., Matsuzawa, A., Ichijo, H.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 7522-7531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023013
[Journal Article] ER stress-induced cell death and inflammatory signaling: a therapeutic insight into intractable diseases.
- Author(s)
  Shimizu, Y., Naguro, I., Nishitoh, H., Ichijo, H.
- Journal Title
  
  Endoplasmic Reticulum Stress and Human Disease (in press)
- Data Source
  KAKENHI-PROJECT-20790058
[Journal Article] CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
- Author(s)
  Maruyama, T., Kadowaki, H., Okamoto, N., Nagai, A., Naguro, I., Matsuzawa, A., Shibuya, H., Tanaka, K., Murata, S., Takeda, K., Nishitoh, H., Ichijo, H.
- Journal Title
  
  EMBO J. (in press)
- Data Source
  KAKENHI-PROJECT-20790058
[Journal Article] Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAP kinase pathway for extracelluler ATP-induced apoptosis in macrophage
- Author(s)
  Noguchi, T., Ishii, K., Fukutomi, H., Naguro, I., Matsuzawa, A., Takeda, K., Ichijo, H.
- Journal Title
  
  J. Biol. Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023013
[Presentation] 哺乳類細胞が備える両方向性の浸透圧ストレスシグナル伝達2024
- Author(s)
  名黒功
- Organizer
  第9回お茶の水サイエンス倶楽部
- Invited
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 哺乳類細胞が備える両方向性の浸透圧ストレスシグナル伝達2024
- Author(s)
  名黒功
- Organizer
  第9回お茶の水サイエンス倶楽部
- Invited
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] マクロファージの高浸透圧ストレス応答におけるNFAT5制御分子としてのHES1の機能解析2023
- Author(s)
  足立　浩輝、立野　浩輝、名黒　功、一條　秀憲
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 浸透圧ストレスはミトコンドリアで直接感知されPDKを介して糖代謝を迅速・可逆的に変化させる2023
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第75回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 浸透圧ストレス受容モジュールASK3 condensateの形成と流動性制御2023
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] 浸透圧ストレスはミトコンドリアで直接感知されPDKを介して糖代謝を迅速・可逆的に変化させる2023
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第75回日本細胞生物学会大会75
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] Sodium ion regulates liquidity of biomolecular condensates in hyperosmotic stress response2023
- Author(s)
  Morishita, K., Watanabe, K., Naguro, I., Ichijo, H.
- Organizer
  KEYSTONE SYMPOSIA ON Molecular and Cellular Biology , BIOMOLECULAR CONDENSATES: EMERGING CELLULAR AND BIOPHYSICAL ROLES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 浸透圧ストレス受容モジュールASK3 condensateの形成と流動性制御2023
- Author(s)
  名黒功、一條　秀憲
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 浸透圧ストレスの細胞応答機構2023
- Author(s)
  名黒　功
- Organizer
  第7回日本メカノバイオロジー学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] マクロファージの高浸透圧ストレス応答におけるNFAT5制御分子としてのHES1の機能解析2023
- Author(s)
  足立　浩輝、立野　浩輝、名黒　功、一條　秀憲
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] Stress-dependent dephosphorylatio is mediated by boundary surface between ASK3 and PP6 condensates to regulate cellular osmotic response2023
- Author(s)
  Naguro, I., Morishita, K., Watanabe, K., Ichijo, I.
- Organizer
  KEYSTONE SYMPOSIA ON Molecular and Cellular Biology , BIOMOLECULAR CONDENSATES: EMERGING CELLULAR AND BIOPHYSICAL ROLES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 浸透圧ストレスの細胞応答機構2023
- Author(s)
  名黒功
- Organizer
  第7回日本メカノバイオロジー学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 高浸透圧ストレスにおけるNFAT5制御分子としてのHES1の機能解析2022
- Author(s)
  足立　浩輝、立野　浩輝、名黒　功、一條　秀憲
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 浸透圧センサーキナーゼASK3の機能と役割2022
- Author(s)
  名黒　功
- Organizer
  第26回日本臨床内分泌学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 哺乳類細胞における浸透圧の感知と応答を担う分子機構2022
- Author(s)
  名黒功
- Organizer
  第6回日本臨床薬理学会中国・四国地方会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 高浸透圧ストレスにおけるNFAT5制御分子としてのHES1の機能解析2022
- Author(s)
  足立　浩輝、立野　浩輝、名黒　功、一條　秀憲
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] キナーゼシグナルが制御する両方向性の浸透圧ストレス応答2022
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] 哺乳類細胞における浸透圧の感知と応答を担う分子機構2022
- Author(s)
  名黒　功
- Organizer
  第6回日本臨床薬理学会中国・四国地方会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19324
[Presentation] Stress-dependent liquid-liquid phase separation establishes an osmo-sensing module through the regulation of ASK32022
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] Bidirectional osmotic stress response via kinase signaling2022
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 高浸透圧ストレス下でナトリウムイオンが細胞内液滴の流動性を制御する2022
- Author(s)
  森下　和浩、渡邊　謙吾、名黒　功、一條　秀憲
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24024
[Presentation] 浸透圧ストレスに誘導される細胞代謝の変化2021
- Author(s)
  名黒功、生澤孟志
- Organizer
  第5回メカノバイオロジー学会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 高浸透圧環境におけるストレス応答および免疫応答に対する新規NFAT5制御分子HES1の機能解析2020
- Author(s)
  立野浩輝、名黒功、一條秀憲
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] Signaling mechanisms and physiological roles of osmotic stress response2020
- Author(s)
  Isao Naguro, Hidenori Ichijo
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 高浸透圧ストレスにより起きる代謝リプログラミングとその生理的意義2020
- Author(s)
  生澤孟志、名黒功、池田和貴、有田誠、一條秀憲
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] TRPM4は細胞内液滴の流動性制御を介してASK3不活性化に寄与する2020
- Author(s)
  森下和浩、渡邊謙吾、名黒功、一條秀憲
- Organizer
  第19回次世代を担う若手のためのファーマ・バイオフォーラム（薬学会）
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] Scribble欠損細胞から分泌されるFGF21は細胞競合を誘導する2020
- Author(s)
  小川基行、名黒功、一條秀憲
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 細胞競合によるScribble欠損細胞の排除機構の解析2020
- Author(s)
  小川基行、名黒功、一條秀憲
- Organizer
  第19回次世代を担う若手のためのファーマ・バイオフォーラム（薬学会）
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 高浸透圧環境におけるストレス応答および免疫応答に対する新規NFAT5制御分子HES1の機能解析2019
- Author(s)
  立野浩輝、名黒功、一條秀憲
- Organizer
  第14回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 哺乳類細胞における浸透圧ストレスシグナリングの解明とその役2019
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] 浸透圧勾配が引き起こす上皮細胞シートのドーム形成2019
- Author(s)
  石原（石田）すみれ、秋山　正和、古澤　和也、名黒　功、立野　浩輝、須志田　隆道、石原　誠一郎、芳賀　永
- Organizer
  2018年度日本生物物理学会北海道支部例会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 相分離が高浸透圧ストレス下でのPP6によるASK3不活性化を制御する2019
- Author(s)
  渡邊謙吾、名黒功、一條秀憲
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 高浸透圧ストレスは細胞のミトコンドリア呼吸に関わる代謝を変化させる2019
- Author(s)
  生澤孟志、名黒功、池田和貴、有田誠、一條秀憲
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] NFAT5の高浸透圧応答性を促進するHes1の同定2019
- Author(s)
  名黒　功、立野　浩輝、一條　秀憲
- Organizer
  第71回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] Analysis of HES1 as a Novel Regulator of NFAT5 under Hyper-Osmotic Stress2019
- Author(s)
  Hiroki Ryuno, Isao Naguro, Hidenori Ichijo
- Organizer
  FASEB Science Research Conference (The Molecular Mechanisms of Immune Cell Development and Function Conference)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 哺乳類細胞における浸透圧ストレスシグナリングの解明とその役割2019
- Author(s)
  名黒功、一條秀憲
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] シングルセルウェスタン法を用いた細胞の浸透圧ストレス応答の解析2019
- Author(s)
  名黒　功、立野　浩輝
- Organizer
  第4回メカノバイオロジー学会
- Data Source
  KAKENHI-PROJECT-15KK0297
[Presentation] シングルセルウェスタン法を用いた細胞の浸透圧ストレス応答の解析2019
- Author(s)
  名黒　功、立野　浩輝
- Organizer
  第4回メカノバイオロジー学会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 高浸透圧環境におけるストレス応答および免疫応答に対する新規NFAT5制御分子HES1の機能解析2019
- Author(s)
  立野浩輝、名黒功、一條秀憲
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] アセトアミノフェン誘導性肝障害 (AILF) におけるストレス応答キナーゼASK3の機能解析2019
- Author(s)
  関口雅子、名黒功、一條秀憲
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] NFAT5の高浸透圧応答性を促進するHes1の同定2019
- Author(s)
  名黒功、立野浩輝、一條秀憲
- Organizer
  第19回日本蛋白質科学会年会、第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] NFAT5の高浸透圧応答性を促進するHes1の同定2019
- Author(s)
  名黒　功、立野　浩輝、一條　秀憲
- Organizer
  第71回　日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-15KK0297
[Presentation] プロテアソーム依存的なASK3の不活性化による高浸透圧ストレス応答の制御2018
- Author(s)
  周　翔宇、渡邊　謙吾、森下　和浩、名黒　功、一條　秀憲
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] 新規NFAT5核内移行制御因子HES1の同定と高浸透圧環境における機能2018
- Author(s)
  立野　浩輝、名黒　功、一條　秀憲
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15KK0297
[Presentation] 浸透圧ストレス応答を担うシグナル伝達分子の同定と解析2018
- Author(s)
  名黒　功
- Organizer
  広島大学　分子細胞情報学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] プロテアソーム依存的なASK3の不活性化による高浸透圧ストレス応答の制御2018
- Author(s)
  周　翔宇、渡邊　謙吾、森下　和浩、名黒　功、一條　秀憲
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 新規NFAT5核内移行制御因子HES1の同定と高浸透圧環境における機能2018
- Author(s)
  立野　浩輝、名黒　功、一條　秀憲
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02569
[Presentation] 抗腫瘍性免疫におけるASK1の機能解析2017
- Author(s)
  布施耕介、神山美樹、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] PP6-ASK3モジュールは浸透圧ストレス応答の重要な変換器である2017
- Author(s)
  渡邊謙吾、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 血小板と血管内皮細胞におけるASK1が協調的に肺へのがん転移を制御する2017
- Author(s)
  神山美樹、名黒功、一條秀憲
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] Death pattern shift from apoptosis to parthanatos regulated by the strength of oxicative stress and ASK1 signaling2017
- Author(s)
  Nishida, T., Naguro, I. and Ichijo, H.
- Organizer
  FASEB NAD+ -Metabolism and Signaling-
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 抗腫瘍性免疫におけるASK1の機能解析2017
- Author(s)
  布施耕介、神山美樹、名黒功、一條秀憲
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] Scribble欠損誘導性細胞競合モデルにおける細胞遊走因子の関与2017
- Author(s)
  小川基行、河原崎陽介、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] Scribble KDによるSARM1の発現上昇が細胞脆弱性を誘導する2017
- Author(s)
  河原崎陽介、小川基行、中村俊崇、名黒功、一條秀憲
- Organizer
  第3回メカノバイオロジー学会
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 血管内皮細胞におけるASK1が肺へのがん転移を制御する2017
- Author(s)
  古川夏輝、神山美樹、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 新規細胞体積調節分子ASK3と制御分子mGluR5の同定2017
- Author(s)
  丹羽國祥(渡邊謙吾)、渡邊謙吾、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 新規 NFAT5核内移行制御因子 HES1の高浸透圧環境における機能解析2017
- Author(s)
  立野浩輝、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 酸化ストレス強度依存的な細胞死パターンシフトの解析2017
- Author(s)
  西田卓人、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ASK1-JNK/p38 axis regulates tumor lung metastasis and platelet functions through phosphorylation of ADP receptor P2Y122017
- Author(s)
  Miki Kamiyama, Kosuke Fuse, Isao Naguro, Hidenori Ichijo
- Organizer
  KEYSTONE SYMPOSIA on Kinases: Nest-Generation Insights and Approaches
- Place of Presentation
  Colorado, USA
- Year and Date
  2017-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 細胞の浸透圧ストレス応答の分子メカニズム～高浸透圧で形成されるASK3グラニュールの解析～2017
- Author(s)
  名黒功
- Organizer
  第2回日本メカノバイオロジー学会
- Place of Presentation
  京都大学（京都府、京都市）
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 細胞競合におけるFGF1及びFGF21によるScribble欠損細胞の排除機構の解析2017
- Author(s)
  小川基行、河原崎陽介、中村俊崇、名黒功、一條秀憲
- Organizer
  第3回メカノバイオロジー学会
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ASK1-JNK/p38 axis regulates tumor lung metastasis and platelet functions through phosphorylation of ADP receptor P2Y122017
- Author(s)
  Miki Kamiyama1, Kosuke Fuse1, Isao Naguro1, Hidenori Ichijo1
- Organizer
  Keystone Symposia Kinases: Next-Generation Insights and Approaches
- Place of Presentation
  Colorado, United States of America
- Year and Date
  2017-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 血小板と血管内皮細胞におけるASK1が協調的に肺へのがん転移を制御する2017
- Author(s)
  神山美樹、大亀美桜、古川夏輝、名黒功、一條秀憲
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] がん転移におけるASKファミリーの機能解析2017
- Author(s)
  布施耕介、神山美樹、名黒功、一條秀憲
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] NAMPT and RNF146 regulates the bidirectional cell volume regulator, ASK32017
- Author(s)
  Watanabe, K., Naguro, I. and Ichijo, H.
- Organizer
  FASEB NAD+ -Metabolism and Signaling-
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ネクローシスにおけるASK1シグナル2017
- Author(s)
  服部一輝、名黒功、一條秀憲
- Organizer
  第26回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ASK1 signaling regulates brown adipocyte maturation2017
- Author(s)
  Hattori, K., Wakatsuki, H., Naguro, I. and Ichijo, H.
- Organizer
  Keystone Symposia Kinases: Next-Generation Insights and Approaches
- Place of Presentation
  Colorado, United States of America
- Year and Date
  2017-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 血小板におけるASK1がADP受容体P2Y12のリン酸化を介して肺へのがん転移を制御する2017
- Author(s)
  神山美樹、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] がん細胞におけるASK1ががん転移時に果たす機能の解析2017
- Author(s)
  大亀美桜、神山美樹、名黒功、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] レポーターマウスを用いた浸透圧応答性キナーゼASK3の組織発現分布の解析2017
- Author(s)
  名黒功、小原圭吾、一條秀憲
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 高浸透圧ストレス下形成されるASK3顆粒構成因子の解析2016
- Author(s)
  椎崎繁、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 酸化ストレスにより引き起こされるネクローシス様細胞死の解析2016
- Author(s)
  西田卓人、名黒功、一條秀憲
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] ASK1-p38 axis regulates cold stress-induced cell death2016
- Author(s)
  Kazuki Hattori, Chihiro Sakauchi, Isao Naguro and Hidenori Ichijo
- Organizer
  Gordon Research Conferences -Cell Death-
- Place of Presentation
  PGA Catalunya BUsiness and Convention Centre (Girona, Spain)
- Year and Date
  2016-07-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 抗腫瘍性免疫におけるASK1の機能解析2016
- Author(s)
  布施耕介、神山美樹、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 浸透圧応答性キナーゼASK3のプロテアソームによる活性制御2016
- Author(s)
  周翔宇、渡邊謙吾、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ASK1 in platelets and vascular endothelial cells coordinately regulates tumor lung metastasis2016
- Author(s)
  Miki Kamiyama、Isao Naguro、Hidenori Ichijo
- Organizer
  第41回内藤コンファレンス
- Place of Presentation
  ガトーキングダム（北海道札幌市）
- Year and Date
  2016-07-04
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] ASK1 in platelets and vascular endothelial cells coordinately regulates tumor lung metastasis2016
- Author(s)
  Miki Kamiyama, Isao Naguro, Hidenori Ichijo
- Organizer
  第41回内藤コンファレンス
- Place of Presentation
  シャトレーゼガトーキングダム札幌（北海道、札幌市）
- Year and Date
  2016-07-05
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 酸化ストレス依存的な細胞死におけるMAPKの活性化パターンのシングルセル解析2016
- Author(s)
  石川万葉、名黒功、一條秀憲
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 酸化ストレス依存的な細胞死におけるMAPKの活性化パターンのシグナルセル解析2016
- Author(s)
  石川万葉、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] Stress signaling in tumorigenesis and tumor metastasis2016
- Author(s)
  Miki Kamiyama, Isao Naguro, Hidenori Ichijo
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 血小板と血管内皮細胞におけるASK1が協調的に肺へのがん転移を制御する ASK1 in platelets and vascular endothelial cells coordinately regulates tumor lung metastasis2016
- Author(s)
  神山美樹、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] NADによる高浸透圧ストレス依存的ASK3不活性化制御2016
- Author(s)
  渡邊謙吾、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ASK1 regulates tumor lung metastasis and platelet functions2016
- Author(s)
  Miki Kamiyama, Isao Naguro, Hidenori Ichijo
- Organizer
  International Conference on Thrombosis and Hemostasis In Cancer
- Place of Presentation
  Bergamo, Italy
- Year and Date
  2016-04-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 細胞膨張感知分子を同定するためのゲノムワイドsiRNAスクリーニング Genome-wide siRNA Screens for Volume Sensors in Cell Swelling2016
- Author(s)
  丹羽國祥，渡邊謙吾，名黒功，一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 血小板と血管内皮細胞におけるASK1が協調的に肺へのがん転移を制御する2016
- Author(s)
  神山美樹、名黒功、一條秀憲
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター（大分県、別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 血小板と血管内皮細胞におけるASK1が協調的に肺へのがん転移を制御する2016
- Author(s)
  神山美樹、名黒功、一條秀憲
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] NFAT5の浸透圧依存的な核内移行制御因子としてのHES1の同定2016
- Author(s)
  立野浩輝、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 酸化ストレス強度依存的な細胞死形態の解析2016
- Author(s)
  西田卓人、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 細胞の浸透圧ストレス応答機構解明を目指したゲノムワイドsiRNAスクリーニング2016
- Author(s)
  名黒　功
- Organizer
  第1回メカノバイオロジー学会
- Place of Presentation
  北海道札幌市（北海道大学）
- Year and Date
  2016-03-01
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] NADによる高浸透圧ストレス依存的ASK3不活性化制御 NAD regulation in ASK3 inactivation under hyperosmotic stress2016
- Author(s)
  渡邊謙吾，名黒功，一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] ASK1 regulates tumor lung metastasis and platelet functions through ADP signaling2016
- Author(s)
  Miki Kamiyama, Isao Naguro, Hidenori Ichijo
- Organizer
  KEYSTONE SYMPOSIA on Purinergic Signaling
- Place of Presentation
  Vancouver, British Columbia, Canada
- Year and Date
  2016-01-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 細胞膨張感知分子を同定するためのゲノムワイドsiRNAスクリーニング2016
- Author(s)
  丹羽國祥、渡邊謙吾、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ASK1 in vascular endothelial cells regulates tumor lung metastasis2016
- Author(s)
  Miki Kamiyama, Isao Naguro, Hidenori Ichijo
- Organizer
  第24回日本血管生物医学会学術集会
- Place of Presentation
  長崎ブリックホール（長崎県、長崎市）
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 浸透圧ストレス応答性キナーゼASK3のプロテアソームによる活性制御 Activity regulation of osmo-responsive kinase ASK3 by proteasome2016
- Author(s)
  周翔宇，渡邊謙吾，名黒功，一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 両方向性の浸透圧ストレスを統御するASK3の研究2016
- Author(s)
  名黒功
- Organizer
  第89回日本生化学会大会　奨励賞受賞講演
- Place of Presentation
  仙台国際センター/東北大学川内キャンパス（宮城県、仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 高浸透圧ストレス下形成されるASK3顆粒構成因子の解析2016
- Author(s)
  椎崎繁、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] Establishment of an image-based detection system of cell death in cell competition to perform a genomewide siRNA screen2016
- Author(s)
  Yosuke Kawarazaki, Isao Naguro and Hidenori Ichijo
- Organizer
  Gordon Research Conferences -Cell Death-
- Place of Presentation
  PGA Catalunya BUsiness and Convention Centre (Girona, Spain)
- Year and Date
  2016-07-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] ASK1シグナルは褐色脂肪細胞の成熟化を制御し、個体の代謝に寄与する ASK1 signaling regulates brown adipocyte maturation and contributes to the metabolic activity2016
- Author(s)
  服部一輝、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 浸透圧ストレス応答性キナーゼASK3のシグナル伝達機構と生理的役割2016
- Author(s)
  名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ASK1 regulates tumor lung metastasis and platelet functions2016
- Author(s)
  Miki Kamiyama, Isao Naguro, Hidenori Ichijo
- Organizer
  8th international conference on thrombosis and hemostasis issues in cancer
- Place of Presentation
  Bergamo, Italy
- Year and Date
  2016-04-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 血小板と血管内皮細胞におけるASK1が協調的に肺へのがん転移を制御する2016
- Author(s)
  神山美樹、名黒功、一條秀憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14445
[Presentation] 高浸透圧ストレス認識機構解明のためのNFAT5を指標とするgenome-wide siRNA screening2015
- Author(s)
  花房　雄介、名黒　功、一條　秀憲
- Organizer
  BMB 2015
- Place of Presentation
  兵庫県神戸市（神戸国際展示場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] PP6・NAMPTによるASK3不活性化は高浸透圧ストレス下の細胞体積回復・生存に重要である2015
- Author(s)
  渡邊　謙吾、名黒　功、一條　秀憲
- Organizer
  BMB 2015
- Place of Presentation
  兵庫県神戸市（神戸国際展示場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] 高浸透圧ストレスにより形成されるASK3グラニュール構成因子の探索2015
- Author(s)
  椎崎　繁、名黒　功、吉田　優、細谷　孝充、一條　秀憲
- Organizer
  BMB 2015
- Place of Presentation
  兵庫県神戸市（神戸国際展示場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ゲノムワイドsiRNAスクリーニングによるASK3を介したRVD経路の制御分子の網羅的探索2015
- Author(s)
  丹羽　國祥、渡邊　謙吾、名黒　功、一條　秀憲
- Organizer
  BMB 2015
- Place of Presentation
  兵庫県神戸市（神戸国際展示場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ストレス応答MAP3K分子ASK3のアセトアミノフェン誘導生肝障害への関与2015
- Author(s)
  町田　俊也、名黒　功、一條　秀憲
- Organizer
  BMB 2015
- Place of Presentation
  兵庫県神戸市（神戸国際展示場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04643
[Presentation] ストレス応答性キナーゼASKファミリータンパク質の疾患への関わりと活性制御機構2014
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25650004
[Presentation] Genome-wide siRNA screening for regulators of the osmotic stress-responsive kinase2013
- Author(s)
  Isao Naguro, Kengo Watanabe, Hidenori Ichijo
- Organizer
  Discovery on Target Functional Genomics Screening Strategies
- Place of Presentation
  Boston U.S.A.
- Data Source
  KAKENHI-PROJECT-25650004
[Presentation] 浸透圧ストレスに両方向性に応答するASK3の役割2013
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-25650004
[Presentation] 浸透圧応答性キナーゼ ASK3のHaloTagテクノロジーを利用した結合分子探索2013
- Author(s)
  名黒功、一條秀憲
- Organizer
  第7回メカノセンシング研究会
- Place of Presentation
  札幌
- Year and Date
  2013-03-07
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] 浸透圧ストレスに応答するキナーゼASK3を介する細胞体積と血圧の調節2013
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-25650004
[Presentation] 浸透圧ストレスに両方向性に応答するASK3によるWNK1-SPAK/OSR1経路の制御2012
- Author(s)
  名黒功, 一條秀憲
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] The role of an osmoticstress-responsive kinase ASK3 and anapproach to the molecular mechanism of thecellular osmo-sensing2012
- Author(s)
  Naguro, I., Ichijo, H.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜.
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] ASK3の浸透圧ストレス応答とWNK1-SPAK/OSR1経路の制御2011
- Author(s)
  名黒功、一條秀憲
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] 浸透圧ストレス認識におけるASK3の役割とストレス認識の分子機構へのアプローチ2011
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第34回日本分子生物学会年会(招待講演)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] 両方向性ストレス（浸透圧・温度）に応答するキナーゼASK3の解析2011
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第6回メカノセンシング研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] siGENOME SMARTpoolライブラリーを用いたゲノムワイドsiRNAスクリーニング～ArrayScanを用いたキナーゼ活性解析の応用～2011
- Author(s)
  名黒　功
- Organizer
  サーモサイエンティフィック　ライフサイエンスセミナー「第３回RNAi研究の最前線」(招待講演)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] 浸透圧ストレス応答のシグナリング2011
- Author(s)
  名黒功、一條秀憲
- Organizer
  第3回シグナルネットワーク研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] 浸透圧ストレス応答のシグナリング～特徴的な浸透圧応答を示すASK3の解析～2011
- Author(s)
  名黒　功、一條　秀憲
- Organizer
  第3回シグナルネットワーク研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] siGENOME SMARTpoolライブラリーを用いたゲノムワイドsiRNAスクリーニング～ArrayScanを用いたキナーゼ活性解析の応用～2011
- Author(s)
  名黒　功
- Organizer
  第二回スクリーニング学研究会(招待講演)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] ASK3は浸透圧ストレスに両方向性に応答しWNK1-SPAK/OSR1経路の抑制因子として働く2009
- Author(s)
  名黒功、梅田剛、丸山順一、武田弘資、一條秀憲
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] 浸透圧ストレス応答の新規シグナル伝達経路と血圧調2009
- Author(s)
  名黒功, 他
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] ASK3, a novel ASK family kinase, bidirectionally responds to osmotic stress and negatively regulates WNK1-SPAK/OSR1 pathway2009
- Author(s)
  Naguro, I., Shimizu, Y., Umeda, T., Maruyama, J., Ichijo, H.
- Organizer
  Gordon Research Conferences -Cellular Osmoregulation & Mechanotransduction-
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] ASK3, a novel ASK family kinase, bidirectionally responds to osmotic stress and negatively regulates WNK1-SPAK/OSR1 pathway2009
- Author(s)
  名黒功, et al.
- Organizer
  Gordon Research Conferences -Cellular Osmoregulation & Mechanotransduction-
- Place of Presentation
  University of NewEngland
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] A novel MAP3K, ASK3 regulates WNK-SPAK/OSR1 signal transduction in osmotic stress response2009
- Author(s)
  Naguro, I., et.al.
- Organizer
  Keystone Symposia "Mechanotransduction in Physiology and Disease"
- Place of Presentation
  Taos, New Mexico, USA
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] The role of ASK3 signal transduction in osmotic astress response.2008
- Author(s)
  Isao Naguro, et. al.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18890050
[Presentation] 新規MAP3KであるASK3の浸透圧ストレス応答におけるWNK-SPAK/OSR1シグナル伝達経路の制御2008
- Author(s)
  名黒功、橋本淳、梅田剛、武田弘資、一條秀憲
- Organizer
  BMB2008第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] ASK family kinases regulate the counteracting roles of apoptosis and inflammation in tumorigenesis2008
- Author(s)
  Naguro, I., et.al.
- Organizer
  Gordon Research Conferences
- Place of Presentation
  USA, Biddefor, ME
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] ASK family kinases regulate the counteracting roles of apoptosis and inflammation in tumorigenesis2008
- Author(s)
  Naguro, I.
- Organizer
  Gordon Research Conferences
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-20790058
[Presentation] Apoptosis signal-regulating kinase 2(ASK2)functions as a MAP3K in a heteromeric complex with ASK12007
- Author(s)
  名黒功, 他
- Organizer
  第八回文部科学省特定領域研究「がん」5領域若手研究者ワークショップ
- Place of Presentation
  蓼科
- Data Source
  KAKENHI-PROJECT-18890050
[Presentation] 浸透圧ストレス応答におけるASK3シグナル伝達経路の解析2007
- Author(s)
  名黒功, 他
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会合同大会(BMB2007)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18890050
[Presentation] Oxidative stress-activated kinase ASK1 is involved in the tumorigenesis and tumor metastasis
- Author(s)
  Isao Naguro, Miki Kamiyama, Hidenori Ichijo
- Organizer
  Gordon Research Conference Tiol-Based Redox Regulation & Signaling
- Place of Presentation
  Girona, Spain
- Year and Date
  2014-07-20 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25650004
[Presentation] Oxidative stress-activated kinase ASK1 is involved in the tumorigenesis and tumor metastasis
- Author(s)
  Naguro, I., Kamiyama, M., Ichijo, H.
- Organizer
  Thiol-Based Redox Regulation & Signaling(Gordon Research Conference)
- Place of Presentation
  Girona, Spain
- Year and Date
  2014-07-20 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25221302
[Presentation] 浸透圧応答性キナーゼASK3のHaloTagテクノロジーを利用した結合分子探索
- Author(s)
  名黒功　他
- Organizer
  第7回メカノセンシング研究会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790078
[Presentation] Ask1 is involved in tumor metastasis in lung metastasis model through regulation of platelet functions
- Author(s)
  Naguro, I., Ichijo, H., Kamiyama, M.
- Organizer
  Next-Gen Kinase Inhibitors
- Place of Presentation
  ボストン,USA
- Year and Date
  2013-06-17 – 2013-06-19
- Data Source
  KAKENHI-PROJECT-25221302
[]

1. NISHITOH Hideki (00332627)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. ICHIJO Hidenori (00242206)

# of Collaborated Projects: 3 results

# of Collaborated Products: 43 results
3. 野口拓也 (20431893)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. 武田弘資 (10313230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. Mori Kazutoshi (70182194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. FUJISAWA Takao (50636644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SEKINE Shiori (70612654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 尾野雅哉 (00270900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 片桐豊雅 (60291895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 蜷川暁 (80647991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAMIYAMA Miki

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
12. Herr Amy E.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Zhang Yizhe

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. FURUSAWA Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. OKABE Kohki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. KADOWAKI Hisae

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. NAGAMATSU Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 松沢厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 小池正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 渡邊謙吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 藤田恭之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 藤井知行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 丸山順一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 濱崎純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Naguro Isao 名黒 功

NAGURO Isao 名黒 功

Research Projects

Research Products

Co-Researchers

体内局所Na環境がマクロファージ細胞を制御する分子機序の解明と病態関与の理解Principal Investigator

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Development of genetically modified mice (Osmonitoring mice) that monitor osmotic environment in the body for an understanding of immune regulationPrincipal Investigator

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Elucidation of multilayered cellular responses to osmotic environment and functions of the response in macrophagesPrincipal Investigator

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Elucidation of osmo-physiology through analysis where and how osmotic circumstance functions in the bodyPrincipal Investigator

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Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum

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Analysis of sensing and responding mechanisms for osmotic stress in mammalian cells(Fostering Joint International Research)Principal Investigator

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The regulatory mechanisms of tumor metastasis via ASK family proteinsPrincipal Investigator

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Analysis of sensing and responding mechanisms for osmotic stress in mammalian cellsPrincipal Investigator

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A genome-wide RNAi screening for clarifying the molecular mechanism of osmotic stress response in the mammalian cellPrincipal Investigator

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Homeostasis Regulation via Stress Signaling and its Molecular Basis for Drug Development

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The analysis of cellular osmotic stress sensing and response by focusing onASK3Principal Investigator

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Drug development by the molecular mechanism-based analysis of stress signaling

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口腔疾患に関わるストレスシグナル解明への遺伝学的アプローチ

Principal Investigator

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Naguro Isao 名黒功

NAGURO Isao 名黒功