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INUI Naoki  乾 直輝

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Inui Naoki  乾 直輝

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Researcher Number 80402254
Other IDs
Affiliation (Current) 2025: 浜松医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 浜松医科大学, 医学部, 教授
2014 – 2019: 浜松医科大学, 医学部, 准教授
2008 – 2012: Hamamatsu University School of Medicine, 医学部, 助教
2010: Hamamatsu University School of Medicine, 医学部・臨床薬理学, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Applied pharmacology
Except Principal Investigator
Medical pharmacy / Basic Section 53030:Respiratory medicine-related / Basic Section 47060:Clinical pharmacy-related / Applied pharmacology
Keywords
Principal Investigator
ブレオマイシン / 線維化 / 肺線維化 / 肺線維症 / 血管内皮細胞 / 間質性肺炎 / 抗癌剤S1 / CYP2A6 / 肺癌 / 抗癌剤S-1 / 個別化治療 / 薬物代謝酵素 / 薬物治療学 … More
Except Principal Investigator
… More 臨床試験 / 薬物相互作用 / PAI-1 / 動脈硬化 / 慢性閉塞性肺疾患(COPD) / 服用性 / がん / 口内炎 / 製剤学的評価 / 院内製剤 / 口腔粘膜炎 / フォーム製剤 / シトクロムP450 / カクテル試験 / 近赤外線時間分解分光法 / 反応性充血 / 血管内皮機能 / 降圧薬 / 健康食品 / 血漿中濃度 / カルシウム拮抗薬 / グレープフルーツジュース / 臨床効果 / 相互作用 / 臨床薬学 Less
  • Research Projects

    (9 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (27 People)
  •  Novel therapeutic strategies for COPD targeting the fibrinolysis inhibitor PAI-1

    • Principal Investigator
      安井 秀樹
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  線維化解除をターゲットとした肺線維化病態の解明と創薬への展開Principal Investigator

    • Principal Investigator
      乾 直輝
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  Preparation and clinical evaluation of foam formulations for the treatment of oral mucositis.

    • Principal Investigator
      Uchida Shinya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      University of Shizuoka
  •  肺血管内皮細胞の低酸素応答による線維化促進の機序解明と治療への応用Principal Investigator

    • Principal Investigator
      乾 直輝
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  Changes in pulmonary endothelial cell and fibroblast properties during bleomycin-induced pulmonary fibrosisPrincipal Investigator

    • Principal Investigator
      Inui Naoki
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hamamatsu University School of Medicine
  •  Development and validation of the cocktail study for the method in detection of drug-drug interactions

    • Principal Investigator
      UCHIDA shinya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      University of Shizuoka
  •  Establishment of novel evaluation methods to measure endothelial functions as a clinical pharmacological tool

    • Principal Investigator
      TAKEUCHI Kazuhiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Hamamatsu University School of Medicine
  •  Effect of the intake of grapefruit juice on blood pressures in hypertensive patients treated with calcium channel blockers

    • Principal Investigator
      UCHIDA Shinya
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      University of Shizuoka
  •  The usefulness of chemotherapy with S-1 for Japanese patients with non-small-cell lung cancer based on CYP2A6*4 gene polymorphismPrincipal Investigator

    • Principal Investigator
      INUI Naoki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Hamamatsu University School of Medicine

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2011 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Neutrophil-lymphocyte ratio being associated with mortality risk in patients receiving antifibrotic therapy2024

    • Author(s)
      Takuma Sho、Suzuki Yuzo、Kono Masato、Hasegawa Hirotsugu、Hashimoto Dai、Yokomura Koshi、Mori Kazutaka、Shimizu Mikihiro、Inoue Yusuke、Yasui Hideki、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Inui Naoki、Suda Takafumi
    • Journal Title

      Respiratory Medicine

      Volume: 223 Pages: 107542-107542

    • DOI

      10.1016/j.rmed.2024.107542

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08279, KAKENHI-PROJECT-23K07598, KAKENHI-PROJECT-21K08176
  • [Journal Article] CD109 Attenuates Bleomycin-induced Pulmonary Fibrosis by Inhibiting TGF-β Signaling2024

    • Author(s)
      Naoi Hyogo、Suzuki Yuzo、Miyagi Asuka、Horiguchi Ryo、Aono Yuya、Inoue Yusuke、Yasui Hideki、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Inui Naoki、Mii Shinji、Ichihara Masatoshi、Takahashi Masahide、Suda Takafumi
    • Journal Title

      The Journal of Immunology

      Volume: 212 Issue: 7 Pages: 1221-1231

    • DOI

      10.4049/jimmunol.2300285

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08279, KAKENHI-PROJECT-23K07598, KAKENHI-PROJECT-23K08306, KAKENHI-PROJECT-21K08176
  • [Journal Article] Impact of preexisting interstitial lung disease on mortality in COVID-19 patients from the early pandemic to the delta variant epidemic: a nationwide population-based study2024

    • Author(s)
      Miyashita Koichi、Hozumi Hironao、Furuhashi Kazuki、Nakatani Eiji、Inoue Yusuke、Yasui Hideki、Suzuki Yuzo、Karayama Masato、Enomoto Noriyuki、Fujisawa Tomoyuki、Inui Naoki、Ojima Toshiyuki、Suda Takafumi
    • Journal Title

      Respiratory Research

      Volume: 25 Issue: 1 Pages: 95-95

    • DOI

      10.1186/s12931-024-02723-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08539, KAKENHI-PROJECT-21K08176
  • [Journal Article] A predictive model for acute exacerbation of idiopathic interstitial pneumonias2023

    • Author(s)
      Karayama Masato、Aoshima Yoichiro、Suzuki Takahito、Mori Kazutaka、Yoshizawa Nobuko、Ichikawa Shintaro、Kato Shinpei、Yokomura Koshi、Kono Masato、Hashimoto Dai、Inoue Yusuke、Yasui Hideki、Hozumi Hironao、Suzuki Yuzo、Furuhashi Kazuki、Fujisawa Tomoyuki、Enomoto Noriyuki、Goshima Satoshi、Inui Naoki、Suda Takafumi
    • Journal Title

      European Respiratory Journal

      Volume: 61 Issue: 5 Pages: 2201634-2201634

    • DOI

      10.1183/13993003.01634-2022

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07388, KAKENHI-PROJECT-21K08176, KAKENHI-PROJECT-20K08539, KAKENHI-PROJECT-23K07598
  • [Journal Article] Geriatric Nutritional Risk Index is a predictor of tolerability of antifibrotic therapy and mortality risk in patients with idiopathic pulmonary fibrosis2023

    • Author(s)
      Mochizuka Yasutaka、Suzuki Yuzo、Kono Masato、Hasegawa Hirotsugu、Hashimoto Dai、Yokomura Koshi、Inoue Yusuke、Yasui Hideki、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Inui Naoki、Nakamura Hidenori、Suda Takafumi
    • Journal Title

      Respirology

      Volume: 28 Issue: 8 Pages: 775-783

    • DOI

      10.1111/resp.14523

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08539, KAKENHI-PROJECT-22K08279, KAKENHI-PROJECT-23K07598, KAKENHI-PROJECT-21K08176
  • [Journal Article] Neutrophil?lymphocyte ratio in patients with idiopathic pleuroparenchymal fibroelastosis2023

    • Author(s)
      Suzuki Yuzo、Kono Masato、Hasegawa Hirotsugu、Hashimoto Dai、Yokomura Koshi、Imokawa Shiro、Inoue Yusuke、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Inui Naoki、Suda Takafumi
    • Journal Title

      BMJ Open Respiratory Research

      Volume: 10 Issue: 1 Pages: e001763-e001763

    • DOI

      10.1136/bmjresp-2023-001763

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08539, KAKENHI-PROJECT-22K08279, KAKENHI-PROJECT-21K08176
  • [Journal Article] CD109 on Dendritic Cells Regulates Airway Hyperreactivity and Eosinophilic Airway Inflammation2023

    • Author(s)
      Aono Yuya、Suzuki Yuzo、Horiguchi Ryo、Inoue Yusuke、Karayama Masato、Hozumi Hironao、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Nakamura Yutaro、Inui Naoki、Mii Shinji、Takahashi Masahide、Suda Takafumi
    • Journal Title

      American Journal of Respiratory Cell and Molecular Biology

      Volume: 68 Issue: 2 Pages: 201-212

    • DOI

      10.1165/rcmb.2022-0109oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08539, KAKENHI-PROJECT-21K08176, KAKENHI-PROJECT-22K07000, KAKENHI-PROJECT-22K08279, KAKENHI-PROJECT-19K17671
  • [Journal Article] Acute exacerbation of rheumatoid arthritis-associated interstitial lung disease: mortality and its prediction model2022

    • Author(s)
      Hozumi Hironao、Kono Masato、Hasegawa Hirotsugu、Kato Shinpei、Inoue Yusuke、Suzuki Yuzo、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Inui Naoki、Nakamura Yutaro、Yokomura Koshi、Nakamura Hidenori、Suda Takafumi
    • Journal Title

      Respiratory Research

      Volume: 23 Issue: 1 Pages: 57-57

    • DOI

      10.1186/s12931-022-01978-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08623, KAKENHI-PROJECT-19K17632, KAKENHI-PROJECT-21K08176, KAKENHI-PROJECT-20K08539
  • [Journal Article] Involvement of autophagy in exacerbation of eosinophilic airway inflammation in a murine model of obese asthma2022

    • Author(s)
      Suzuki Yuzo、Aono Yuya、Akiyama Norimichi、Horiike Yasuoki、Naoi Hyogo、Horiguchi Ryo、Shibata Kiyoshi、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Nakamura Yutaro、Inui Naoki、Suda Takafumi
    • Journal Title

      Autophagy

      Volume: - Issue: 9 Pages: 1-13

    • DOI

      10.1080/15548627.2022.2025571

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17632, KAKENHI-PROJECT-21K08176, KAKENHI-PROJECT-20K08539, KAKENHI-PROJECT-19K17671
  • [Journal Article] Impact of antifibrotic therapy on lung cancer development in idiopathic pulmonary fibrosis2022

    • Author(s)
      Naoi Hyogo、Suzuki Yuzo、Mori Kazutaka、Aono Yuya、Kono Masato、Hasegawa Hirotsugu、Yokomura Koshi、Inoue Yusuke、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Nakamura Yutaro、Inui Naoki、Nakamura Hidenori、Suda Takafumi
    • Journal Title

      Thorax

      Volume: in press Issue: 7 Pages: 1-1

    • DOI

      10.1136/thoraxjnl-2021-218281

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17632, KAKENHI-PROJECT-21K07388, KAKENHI-PROJECT-21K08176, KAKENHI-PROJECT-20K08539
  • [Journal Article] Idiopathic pleuroparenchymal fibroelastosis: three-dimensional computed tomography assessment of upper-lobe lung volume2022

    • Author(s)
      Fukada Atsuki、Suzuki Yuzo、Mori Kazutaka、Kono Masato、Hasegawa Hirotsugu、Hashimoto Dai、Yokomura Koshi、Imokawa Shiro、Tanaka Yuko、Inoue Yusuke、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Nakamura Yutaro、Inui Naoki、Fujino Yoshihisa、Nakamura Hidenori、Suda Takafumi
    • Journal Title

      European Respiratory Journal

      Volume: 60 Issue: 6 Pages: 2200637-2200637

    • DOI

      10.1183/13993003.00637-2022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08539, KAKENHI-PROJECT-21K07388, KAKENHI-PROJECT-21K08176, KAKENHI-PROJECT-22K08279
  • [Journal Article] Molecular Pathogenesis of Pulmonary Fibrosis, with Focus on Pathways Related to TGF-β and the Ubiquitin-Proteasome Pathway2021

    • Author(s)
      Inui, N., Sakai, S., Kitagawa, M
    • Journal Title

      Int. J. Mol. Sci

      Volume: 22 Issue: 11 Pages: 6107-6107

    • DOI

      10.3390/ijms22116107

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08727, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-20K08539
  • [Journal Article] CD248 and integrin alpha-8 are candidate markers for differentiating lung fibroblast subtypes2020

    • Author(s)
      Matsushima Sayomi、Aoshima Yoichiro、Akamatsu Taisuke、Enomoto Yasunori、Meguro Shiori、Kosugi Isao、Kawasaki Hideya、Fujisawa Tomoyuki、Enomoto Noriyuki、Nakamura Yutaro、Inui Naoki、Funai Kazuhito、Suda Takafumi、Iwashita Toshihide
    • Journal Title

      BMC Pulmonary Medicine

      Volume: 20 Issue: 1 Pages: 1-1

    • DOI

      10.1186/s12890-020-1054-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08784, KAKENHI-PROJECT-17K09609, KAKENHI-PROJECT-18H02818
  • [Journal Article] Clinical significance of serum S100 calcium-binding protein A4 in idiopathic pulmonary fibrosis.2019

    • Author(s)
      Akiyama N, Hozumi H, Isayama T, Okada J, Sugiura K, Yasui H, Suzuki Y, Kono M, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Nakamura Y, Suda T.
    • Journal Title

      Respirology

      Volume: 0 Issue: 7 Pages: 0-0

    • DOI

      10.1111/resp.13707

    • NAID

      120007097006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09609, KAKENHI-PROJECT-18K15947, KAKENHI-PROJECT-19K17632, KAKENHI-PROJECT-18H02818
  • [Journal Article] Changes in pulmonary endothelial cell properties during bleomycin-induced pulmonary fibrosis.2018

    • Author(s)
      Kato S, Inui N*, Hakamata A, Suzuki Y, Enomoto N, Fujisawa T, Nakamura Y, Watanabe H, Suda T.
    • Journal Title

      Respir Res.

      Volume: 19 Issue: 1 Pages: 127-127

    • DOI

      10.1186/s12931-018-0831-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09609, KAKENHI-PROJECT-16K19448
  • [Journal Article] カクテル試験を用いた薬物相互作用の網羅的解析法の確立と応用2014

    • Author(s)
      田中紫茉子、内田信也、乾 直輝、渡邉裕司、並木徳之
    • Journal Title

      PROGRESS IN DRUG DELIVERY SYSTEM

      Volume: XXIII Pages: 21-26

    • Data Source
      KAKENHI-PROJECT-26460202
  • [Journal Article] Effect of 2 weeks' consumption of pomegranate juice on the pharmacokinetics of a single dose of midazolam : an open-label, randomized, single-center, 2-period crossover study in healthy Japanese volunteers2011

    • Author(s)
      Shingen Misaka, Reiko Nakamura, Shinya Uchida, Kazuhiko Takeuchi, Norio Takahashi, Naoki Inui, Kazuhiro Kosuge, Shizuo Yamada, Hiroshi Watanabe
    • Journal Title

      Clin. Ther

      Volume: 33 Pages: 246-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590171
  • [Journal Article] Benzbromarone pharmacokinetics and pharmacodynamics in different cytochrome P450 2C9 genotypes2010

    • Author(s)
      Shinya Uchida, Kayoko Shimada, Shingen Misaka, Hiromitu Imai, Yasuhiro Katoh, Naoki Inui, Kazuhiko Takeuchi, Takashi Ishizaki, Shizuo Yamada, Kyoichi Ohashi, Noriyuki Namiki, Hiroshi Watanabe
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 25 Pages: 605-610

    • NAID

      10027743998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590171
  • [Journal Article] Pharmacokinetics and pharmacodynamics of midazolam administered intravenously and orally at low doses to healthy volunteers2010

    • Author(s)
      Shingen Misaka, Shinya Uchida, Hiromitsu Imai, Naoki Inui, Shinichiro Nishio, Kyoichi Ohashi, Hiroshi Watanabe, Shizuo Yamada
    • Journal Title

      Clin. Exp. Pharmacol. Physiol

      Volume: 37 Pages: 290-295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590171
  • [Journal Article] Phase II study of combination chemotherapy with S-1 and weekly cisplatin in patients with previously untreated advanced non-small cell lung cancer.2009

    • Author(s)
      Ozawa Y, Inui N, Naitoh T, Yasuda K, Nagayama M, Shirai T, Suganuma H, Fujii M, Nakamura H, Suda T, Chida K.
    • Journal Title

      Lung Cancer. 63

      Pages: 68-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590536
  • [Journal Article] Effects of statins on the pharmacokinetics of midazolam in healthy volunteers.2009

    • Author(s)
      Kokudai M, Inui N, Takeuchi K, Sakaeda T, Kagawa Y, Watanabe H.
    • Journal Title

      J Clin Pharmacol. 49

      Pages: 568-573

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590536
  • [Journal Article] Effect of thyroid hormone on the activity of CYP3A enzyme in humans.2009

    • Author(s)
      Takahashi N, Inui N, Morita H, Takeuchi K, Uchida S, Watanabe H, Nakamura H.
    • Journal Title

      J Clin Pharmacol. 50

      Pages: 88-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590536
  • [Journal Article] The CYP2A6*4 allele is determinant of S-1 pharmacokinetics in Japanese patients with non-small-cell lung cancer2008

    • Author(s)
      Kaida Y, Inui N, Suda T, Nakamura H, Watanabe H, Chida K
    • Journal Title

      Clin Pharmacol Ther 83

      Pages: 589-594

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590536
  • [Journal Article] 非小細胞肺癌患者における薬物代謝酵素CYP2A6遺伝子多型の存在とS-1の薬物動態に及ぼす影響2008

    • Author(s)
      貝田勇介, 乾直輝, 渡邉裕司
    • Journal Title

      臨床薬理の進歩 29

      Pages: 81-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590536
  • [Journal Article] Response to "The Unanswered Question : What Is the Determinant of S-1 Pharmacokinetics?2008

    • Author(s)
      Kaida Y, Inui N, Suda T, Watanabe H, Chida K.
    • Journal Title

      Clin Pharmacol Ther 84

      Pages: 204-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590536
  • [Presentation] Clinical Utility of Serum S100 Calcium Binding Protein A4 in Idiopathic Pulmonary Fibrosis2019

    • Author(s)
      Akiyama N, Hozumi H, Yasui H, Kono M, Suzuki Y, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Nakamura Y, Suda T
    • Organizer
      American Thoracic Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09609
  • [Presentation] ブレオマイシン誘発性肺線維症モデルマウスにおける肺血管内皮細胞の変化2019

    • Author(s)
      加藤 慎平、乾 直輝、袴田 晃央、鈴木 勇三、榎本 紀之、藤澤 朋幸、中村 祐太郎、渡邊 裕司、須田 隆文
    • Organizer
      日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-17K09609
  • [Presentation] カクテル試験の薬物相互作用検出法としての妥当性の検証2017

    • Author(s)
      野神優月、田中紫茉子、内田信也、篠原美紀、三浦基靖、袴田晃央、小田切圭一、乾直輝、渡邉裕司、並木徳之
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-25
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] カクテル試験での1ポイント採血における血漿中濃度及び尿中代謝比とAUCとの関係―caffeine、losartan及びomeprazoleにおける検討―2016

    • Author(s)
      4.篠原美紀、芝切若奈、内田信也、田中紫茉子、袴田晃央、小田切圭一、乾直輝、渡邉裕司、並木徳之
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] カクテル試験での1ポイント採血における血漿中濃度および尿中代謝比とAUCとの関係―dextromethorphanおよびmidazolamにおける検討―2016

    • Author(s)
      5.芝切若奈、篠原美紀、内田信也、田中紫茉子、袴田晃央、小田切圭一、乾直輝、渡邉裕司、並木徳之
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] CYP1A2, CYP2C9, 2C19, 2D6および3Aの基質薬の血中濃度と, 薬物による誘導・阻害の影響の関連性2015

    • Author(s)
      2.小田切圭一、袴田晃央、片山直紀、宮川幸子、乾直輝、田中紫茉子、内田信也、並木徳之、渡邉裕司
    • Organizer
      第36回日本臨床薬理学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-12-09
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] カクテル試験における基質薬物の血漿中濃度とAUCとの相関性2015

    • Author(s)
      3.田中紫茉子、浜咲理子、乾直輝、渡邉裕司、内田信也、並木徳之
    • Organizer
      第36回日本臨床薬理学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] シトクロムP450酵素誘導の経時的変化2014

    • Author(s)
      乾直輝、内田信也、渡邉裕司
    • Organizer
      第35回日本薬理学会学術総会
    • Place of Presentation
      松山
    • Year and Date
      2014-12-05
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] カクテル試験を用いた薬物相互作用の網羅的解析法の確立と応用2014

    • Author(s)
      田中紫茉子、内田信也、乾直輝、渡邉裕司、並木徳之
    • Organizer
      第23回 DDSカンファランス 2014
    • Place of Presentation
      静岡
    • Year and Date
      2014-09-05
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] Simultaneous LC-MS/MS analysis of the plasma concentrations of a cocktail of 5 cytochrome P450 substrate drugs and their metabolites2014

    • Author(s)
      Shimako Tanaka, Shinya Uchida, Naoki Inui, Kazuhiko Takeuchi, Hiroshi Watanabe, Noriyuki Namiki
    • Organizer
      5th FIP Pharmaceutical Sciences World Congress 2014
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-04-16
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] LC-MS/MSを用いたカクテル試験による薬物相互作用の同時解析2014

    • Author(s)
      内田信也、乾直輝、田中紫茉子、小田切圭一、袴田晃央、渡邉裕司、並木徳之
    • Organizer
      第35回日本薬理学会学術総会
    • Place of Presentation
      松山
    • Year and Date
      2014-12-05
    • Data Source
      KAKENHI-PROJECT-26460202
  • [Presentation] 薬物相互作用検出のためのin vivoでのラットおよび健常人対象試験2011

    • Author(s)
      内田信也、田中紫茉子、乾直輝、竹内和彦、渡邉裕司、大橋京一、並木徳之
    • Organizer
      第32回日本臨床薬理学会年会
    • Place of Presentation
      浜松
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-PROJECT-21590171
  • [Presentation] Inhibitory effects of Omega-6 polyunsaturated fatty acids on endothelial function2011

    • Author(s)
      Wei J, Takeuchi K, Inui N, Watanabe H
    • Organizer
      The 5th China-Japan Joint Meeting of Basic and Clinical Pharmacology
    • Place of Presentation
      Urumqi, China
    • Year and Date
      2011-08-08
    • Data Source
      KAKENHI-PROJECT-22590499
  • [Presentation] ω6-polyunsatulated fatty acids, but not other free fatty acids, evoke endothelial dysfunction by inhibiting store-operated Caentries.2010

    • Author(s)
      竹内和彦、Wei Jiazhang、乾直輝、渡邉裕司
    • Organizer
      16th World congress on Basic and Clinical Pharmacology
    • Place of Presentation
      デンマーク
    • Year and Date
      2010-07-22
    • Data Source
      KAKENHI-PROJECT-22590499
  • [Presentation] The Influence of CYP2A6 Gene Polymorphism on S-1 Therapy in Non-Small-Cell Lung Cancer Patients.2008

    • Author(s)
      Kaida Y, Inui N.
    • Organizer
      American Thoracic Society.
    • Place of Presentation
      Toronto
    • Data Source
      KAKENHI-PROJECT-20590536
  • [Presentation] 非小細胞肺癌患者におけるCYP2A6遺伝子多型とS-1の薬物動態2008

    • Author(s)
      乾直輝
    • Organizer
      日本臨床薬理学会年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590536
  • 1.  須田 隆文 (30291397)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 2.  UCHIDA Shinya (80372522)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 3.  TANAKA Shimako (10559925)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 4.  WATANABE Hiroshi (50262803)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  IMAI Hiromitsu (30398250)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  TAKEUCHI Kazuhiko (00419425)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 7.  小田切 圭一 (70529213)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 8.  CHIDA Kingo (40197611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 9.  YAMADA Hiroshi (40265252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 10.  KOSUGE Kazuhiro (00283375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  袴田 晃央 (60788280)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 12.  小幡 由佳子 (90432210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  柏倉 康治 (70746403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  安井 秀樹 (60804937)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  岩城 孝行 (70509463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  鈴木 優子 (20345812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MIURA Tomoyasu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  SASANO Tomomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  OZAWA Miki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SHINOHARA Miki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 21.  NOGAMI Yuzuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  FUJISAWA Tomouki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  NAKAMURA Yutaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  鈴木 勇三
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 25.  森 雅紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  河崎 秀陽
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  北川 雅敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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