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Tanaka Naoki  田中 直樹

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TANAKA Naoki  田中 直樹

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Researcher Number 80419374
Other IDs
Affiliation (Current) 2020: 信州大学, 学術研究院医学系, 准教授
Affiliation (based on the past Project Information) *help 2015 – 2019: 信州大学, 学術研究院医学系, 准教授
2017: 信州大学, 医学(系)研究科(研究院), 准教授
2010: Shinshu University, 医学(系)研究科(研究院), 助教
2007 – 2009: Shinshu University, 医学系研究科, 助教
Review Section/Research Field
Principal Investigator
Gastroenterology / Experimental pathology / Basic Section 49010:Pathological biochemistry-related
Except Principal Investigator
Pathological medical chemistry / General medical chemistry
Keywords
Principal Investigator
栄養学 / 病理学 / 肝臓病学 / ストレス / 内科 / アルコール / C型肝炎ウイルス / 脂肪肝 / 肝細胞癌 / 非アルコール性脂肪肝炎 … More / 核内受容体 / メタボロミクス / コレステロール毒性 / CD44 / マイクロアレイ解析 / 腸管・肝臓連関 / 疾患モデル動物 / 脂質 / 小胞体ストレス / トランス脂肪酸 / 肝癌 / 腸内細菌 / メタボローム解析 / 機能性食品 … More
Except Principal Investigator
酸化ストレス / スルファチド / アルコール / レシチン / 肝障害 / 炎症 / NF-kB / NF-κB / エタノール / 肝炎 / PPAR / リアルタイムPCR / 胃粘膜 / 野生型マウス / ケモカイン / 生体分子 / PPARα / HCV / トランス脂肪酸 / 肝がん / C型肝炎ウイルスコア蛋白 / PPARalpha / デオキシコール酸 / トランス脂肪酸食 / 肝臓非癌部・癌部 / 脂質 / 発癌 / C型肝炎 Less
  • Research Projects

    (7 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (7 People)
  •  食事中トランス脂肪酸による肝発癌促進機構の解明と予防法の開発Principal InvestigatorOngoing

    • Principal Investigator
      田中 直樹
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Shinshu University
  •  Elucidation of mechanism on hepatitis C-related liver cancer exacerbation by trans-fatty acid toxicity and development of preventive method

    • Principal Investigator
      AOYAMA Toshifumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Shinshu University
  •  Evaluating the pathogenesis of non-alcoholic steatohepatitis from the viewpoint of xenobiotic metabolismPrincipal Investigator

    • Principal Investigator
      TANAKA Naoki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Shinshu University
  •  Studies on a novel oxidative stress-reducing effect resulting from generation/excretion of sulfated glycolipids

    • Principal Investigator
      Nakajima Takero
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Shinshu University
  •  PPARα活性化抑制を標的としたC型肝炎関連肝癌の予防法の開発Principal Investigator

    • Principal Investigator
      田中 直樹
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Shinshu University
  •  Elucidation of molecular mechanisms for alcohol-dependent inflammatory disorders in digestive tract and liver and development of their preventive methods

    • Principal Investigator
      AOYAMA Toshifumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Shinshu University
  •  Analysis of pathogenesis of alcoholic liver disease and development of novel therapies using PPARalpha-null micePrincipal Investigator

    • Principal Investigator
      TANAKA Naoki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Shinshu University

All 2019 2017 2016 2009 Other

All Journal Article Presentation

  • [Journal Article] A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice.2019

    • Author(s)
      Wang X, Tanaka N, Hu X, Kimura T, Lu Y, Jia F, Sato Y, Nakayama J, Moriya K, Koike K, Aoyama T
    • Journal Title

      Arch Toxicol.

      Volume: in press

    • DOI

      10.1007/s00204-019-02440-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08616
  • [Journal Article] Decreased Fatty Acid <i>β</i>-Oxidation Is the Main Cause of Fatty Liver Induced by Polyunsaturated Fatty Acid Deficiency in Mice2017

    • Author(s)
      Nakajima T, Yang Y, Lu Y, Kamijo Y, Yamada Y, Nakamura K, Koyama M, Yamaguchi S, Sugiyama E, Tanaka N, Aoyama T
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 242(3) Issue: 3 Pages: 229-239

    • DOI

      10.1620/tjem.242.229

    • NAID

      130005808367

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08264
  • [Journal Article] Age-dependent PPARalpha activation induces hepatic sulfatide accumulation in transgenic mice carrying the hepatitis C virus core gene2017

    • Author(s)
      Tian Y, Yang Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Lu Y, Moriya K, Koike K, Gonzalez FJ, Aoyama T.
    • Journal Title

      Glycoconjugate Journal

      Volume: 33 Pages: 927-936

    • DOI

      10.1007/s10719-016-9703-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08264, KAKENHI-PROJECT-16K08616
  • [Journal Article] Activation of PPAR<i>α</i> by Fatty Acid Accumulation Enhances Fatty Acid Degradation and Sulfatide Synthesis2016

    • Author(s)
      Yang Y, Feng Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Aoyama T.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 240 Issue: 2 Pages: 113-122

    • DOI

      10.1620/tjem.240.113

    • NAID

      130005245903

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08264
  • [Journal Article] Polyenephosphatidylcholine prevents alcoholic liver disease in PPARa-null mice through attenuation of increases in oxidative stress

    • Author(s)
      Okiyama W, Tanaka N, Nakajima T, Tanaka E, Kiyosawa K, Gonzalez F J, Aoyama T
    • Journal Title

      J Hepatol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590301
  • [Presentation] Polyenephosphatidylcholine prevents alcoholic liver disease in PPARalpha-null mice through attenuation of increases in oxida tive stress2009

    • Author(s)
      Tanaka N, Okiyama W, Aoyama T
    • Organizer
      19^<th> conference of the Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      Hong Kong
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-19590301
  • [Presentation] Polyenephosphatidylcholine prevents alcoholic liver disease in PPARalpha-null mice through attenuation of increases in oxidative stress2009

    • Author(s)
      Tanaka N, Okiyama Y, Aoyama T
    • Organizer
      19^<th> Conference of the Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      Hong Kong
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-19790476
  • [Presentation] アルコール性肝炎に対するポリエンフォスファチジルコリンの有用性2009

    • Author(s)
      田中直樹, 小松通治, 青山俊文
    • Organizer
      第12回日本病態栄養学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-01-11
    • Data Source
      KAKENHI-PROJECT-19790476
  • [Presentation] Polyenephosphatidylcholine prevents alcoholic liver disease in PPARalpha-null mice through attenuation of increases in oxidative stress2009

    • Author(s)
      Tanaka N, Okiyama W, Aoyama T
    • Organizer
      19^<th> conference of the Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      The People's Republic of China
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-19790476
  • 1.  AOYAMA Toshifumi (50231105)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 2.  Nakajima Takero (30581011)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  NAKAMURA Kozo (20345763)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  KAMIJO Yuji (50377636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  長屋 匡信 (00718033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Gonzalez Frank j
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKAHASHI Shogo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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