Tominaga Tatsuya 冨永辰也

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TOMINAGA Tatsuya 冨永辰也

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Researcher Number	80425446
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 徳島大学, 大学院医歯薬学研究部(医学域), 教授 2018 – 2022: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授 2017: 徳島大学, 医歯薬学研究部, 准教授 2017: 徳島大学, 大学院医歯薬学研究部, 准教授 2016: 徳島大学, 大学院医歯薬学研究部(医学系), 助教 … More 2011 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教 2012: 徳島大学, 大学院・へルスバイオサイエンス研究部, 助教 2010 – 2012: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 2011: 徳島大学, 大学院・ヘルスバイオサイエンス研究科, 助教 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Basic Section 52010:General internal medicine-related / Basic Section 57060:Surgical dentistry-related / Laboratory medicine
Keywords	Principal Investigator BMP4 / ポドサイト障害 / 糖尿病 / PACE4 / サイトカイン / 慢性腎臓病 / 糖尿病性腎症 / 高血圧 / 動脈硬化 / 糖尿病性腎臓病(DKD) … More / Estrogen / ERR / DKD / 腎硬化症 / アルブミン尿 / アポトーシス / Bmp4 … More Except Principal Investigator バイオマーカー / 慢性腎臓病 / 糖尿病性腎症 / ポドサイト / 糸球体硬化 / メサンギウム細胞 / BMP4 / Smad1 / 糖尿病 / ヘプシジン / フェロトーシス / 細胞外基質小胞 / 骨芽細胞 / 骨髄腫 / 細胞老化 / ループス腎炎 / 糖尿病性腎臓病 / オートファジー / 修復 / nephroid / 早期老化 / 糸球体様スフェロイド / Liquid Biopsy / exosome / 糸球体用スフェロイド / シグナル伝達 / 発生・分化 / 内科 / 細胞内シグナル伝達 / smad1 / mTOR経路 / 細胞伝達経路 / ALK1 / エクソソーム / CKD / エクソゾーム / 分子標的治療 / ALK3/6 / BMP / 抗体医療 / Sox9 / TGF-β / 抗体治療 / TGFβ / アクチン骨格 / Tpbg / 糖膜蛋白 / 糸球体腎炎 / MGP / 血管合併症 Less

骨形成環境による腫瘍排他的ニッチの分子機序の解明：新たながん治療戦略の可能性
- Principal Investigator
  
  寺町順平
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
多元的フェロトーシス治療に基づく慢性腎臓病治療戦略の開発
- Principal Investigator
  
  田蒔昌憲
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokushima
Development of a method for differentiating various renal disorders by analyzing podocyte activation signals
- Principal Investigator
  
  SAKURAI Akiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokushima
Elucidation of the molecular mechanisms responsible for the recent increase in DKDPrincipal Investigator
- Principal Investigator
  
  TOMINAGA Tatsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokushima
The role of autophagy in mesangial cells in the development of chronic kidney disease
- Principal Investigator
  
  長井幸二郎
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokushima
Identification of specific podocyte-damaging molecules in diabetic nephropathy and establishment of urinary biomarkers
- Principal Investigator
  
  SAKURAI Akiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokushima
糖尿病における進行性腎障害の病態特異的バイオマーカー樹立と修復機構解明
- Principal Investigator
  
  安部秀斉
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokushima
Development of new CKD therapeutic agent targeting cytokine processing enzymePrincipal Investigator
- Principal Investigator
  
  TOMINAGA Tatsuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
The role of mesangial cells in glomeruli formation and the development of diabetic kidney disease
- Principal Investigator
  
  NAGAI Kojiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Role of cell signaling pathway in mesangial cells in the progression of chronic kidney disease
- Principal Investigator
  
  NAGAI Kojiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
慢性腎臓病(CKD)における糖尿病血管合併症の成因解明Principal Investigator
- Principal Investigator
  
  冨永辰也
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Establishment of non-invasive diagnostic method for CKD by using urinary exosomes.
- Principal Investigator
  
  DOI Toshio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Development of Specific Biomarker and Molecular Targeting Therapy for Diabetic Nephropathy by RAS-independent Pathway
- Principal Investigator
  
  DOI Toshio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima
Establishment and evaluation of the measurement of serum Smad1 in diabetic vascular complications.
- Principal Investigator
  
  KONDO Naoki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagawa University
  The University of Tokushima
Analysis for novel role of Tpbg in podocyte in glomerulonephritis.
- Principal Investigator
  
  MATSUURA Motokazu, 村上太一
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokushima

All 2022 2021 2019 2018 2017 2016 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction2021
- Author(s)
  Ueda Sayo、Tominaga Tatsuya、Ochi Arisa、Sakurai Akiko、Nishimura Kenji、Shibata Eriko、Wakino Shu、Tamaki Masanori、Nagai Kojiro
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-021-01150-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08593, KAKENHI-PROJECT-21K07367, KAKENHI-PROJECT-21K15663
[Journal Article] All-trans retinoic acid suppresses bone morphogenetic protein 4 in mouse diabetic nephropathy through a unique retinoic acid response element2019
- Author(s)
  Tamaki Masanori、Tominaga Tatsuya、Fujita Yui、Koezuka Yasuhiko、Ichien Go、Murakami Taichi、Kishi Seiji、Yamamoto Keiichi、Abe Hideharu、Nagai Kojiro、Doi Toshio
- Journal Title
  
  American Journal of Physiology-Endocrinology and Metabolism
  
  Volume: 316 Issue: 3 Pages: E418-E431
- DOI
  10.1152/ajpendo.00218.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09619, KAKENHI-PROJECT-16K19490
[Journal Article] Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy2019
- Author(s)
  Sakurai Akiko、Ono Hiroyuki、Ochi Arisa、Matsuura Motokazu、Yoshimoto Sakiya、Kishi Seiji、Murakami Taichi、Tominaga Tatsuya、Nagai Kojiro、Abe Hideharu、Doi Toshio
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 5 Pages: e0216788-e0216788
- DOI
  10.1371/journal.pone.0216788
- NAID
  120006812013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415
[Journal Article] An adjustment in BMP4 function represents a treatment for diabetic nephropathy and podocyte injury2018
- Author(s)
  Fujita Yui、Tominaga Tatsuya、Abe Hideharu、Kangawa Yumi、Fukushima Naoshi、Ueda Otoya、Jishage Kou-ichi、Kishi Seiji、Murakami Taichi、Saga Yumiko、Kanwar Yashpal S.、Nagai Kojiro、Doi Toshio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 13011-13011
- DOI
  10.1038/s41598-018-31464-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08245, KAKENHI-PROJECT-16K09619
[Journal Article] Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy2018
- Author(s)
  Ono Hiroyuki、Abe Hideharu、Sakurai Akiko、Ochi Arisa、Tominaga Tatsuya、Tamaki Masanori、Kishi Seiji、Murakami Taichi、Nagai Kojiro、Kohashi Masayuki、Doi Toshio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10548-10548
- DOI
  10.1038/s41598-018-28439-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07415, KAKENHI-PROJECT-18K08245, KAKENHI-PROJECT-16K09619
[Journal Article] Urinary IgG4 and Smad1 are Specific Biomarkers for Renal Structural and Functional Changes in Early Stage of Diabetic Nephropathy.2018
- Author(s)
  Doi T, Moriya T, Fujita Y, Minagawa N, Usami M, Sasaki T, Abe H, Kishi S, Murakami T, Ouchi M, Ichien G, Yamamoto K, Ikeda H, Koezuka Y, Takamatsu N, Shima K, Mauer M, Nagai K, Tominaga T.
- Journal Title
  
  Diabetes
  
  Volume: 67 Issue: 5 Pages: 986-993
- DOI
  10.2337/db17-1043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09265, KAKENHI-PROJECT-16K09619
[Journal Article] Mesangial cell mTORC1 activation results in mesangial expansion2017
- Author(s)
  Kojiro Nagai, Tatsuya Tominaga, Sayo Ueda, Eriko Shibata, Masanori Tamaki, Motokazu Matsuura, Seiji Kishi, Taichi Murakami, Tatsumi Moriya, Hideharu Abe, Toshio Doi
- Journal Title
  
  Journal of American Society of Nephrology
  
  Volume: 28 Issue: 10 Pages: 2879-2885
- DOI
  10.1681/asn.2016111196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09619
[Journal Article] Polymorphism in the human matrix Gla protein gene is associated with the progression of vascular calcification in maintenance hemodialysis patients2013
- Author(s)
  Yoshikawa K, Abe H, Tominaga T, Nakamura M, Kishi S, Matsuura M, Nagai K, Tsuchida K, Minakuchi J, Doi T
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 17 Issue: 6 Pages: 882-889
- DOI
  10.1007/s10157-013-0785-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] Scleraxis modulates bone morphogenetic protein 4 (BMP4)-Smad1-smooth muscle α actin(SMA) signal transduction in diabetic nephropathy2012
- Author(s)
  Abe H, Tominaga T, Matsubara T, Abe N, Kishi S, Nagai K, Murakami T, Araoka T, Doi T.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 24 Pages: 20430-20442
- DOI
  10.1074/jbc.m111.275610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-22390169, KAKENHI-PROJECT-23659445, KAKENHI-PROJECT-24591201, KAKENHI-PROJECT-24659279
[Journal Article] Activation of bone morphogenetic protein 4 signaling leads to glomerulo sclerosis that mimics diabetic nephropathy2011
- Author(s)
  Tominaga T., et al
- Journal Title
  
  J Biol Chem
  
  Volume: 286(37) Pages: 20109-20116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590628
[Journal Article] BMP4・Smad1シグナルと糖尿病性腎症2011
- Author(s)
  安部秀斉、冨永辰也、松原雄、土井俊夫
- Journal Title
  
  日本腎臓学会誌
  
  Volume: vol.53, No.7 Pages: 1000-1005
- NAID
  10030343457
- Data Source
  KAKENHI-PROJECT-21590628
[Journal Article] BMP4・Smad1シグナルと糖尿病性腎症2011
- Author(s)
  安部秀斉、冨永辰也, 松原雄, 土井俊夫
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 53(7) Pages: 1000-1005
- NAID
  10030343457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659445
[Journal Article] Sox9 induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy2011
- Author(s)
  Kishi S, Abe H, Akiyama H, Tominaga T, Murakami T, Mima A, Nagai K, Kishi F, Matsuura M, Matsubara T, Iehara N, Ueda O, Fukushima N, Jishage KI, Doi T.
- Journal Title
  
  J Biol Chem
  
  Volume: 286(37) Issue: 37 Pages: 32162-9
- DOI
  10.1074/jbc.m111.244541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591032, KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis2011
- Author(s)
  Mima A, Abe H, Nagai K, Arai H, Matsubara T, Araki M, Torikoshi K, Tominaga T, Iehara N, Fukatsu A, Kita T, Doi T
- Journal Title
  
  PLoS One.
  
  Volume: 6(3) Issue: 3 Pages: e17929-e17929
- DOI
  10.1371/journal.pone.0017929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy2011
- Author(s)
  Tominaga T, Abe H, Ueda O, Goto C, Nakahara K, Murakami T, Mima A, Nagai K, Araoka T, Kishi S, Fukushima N, Jishage KI, Doi T
- Journal Title
  
  J Biol Chem
  
  Volume: 286(22) Issue: 22 Pages: 20109-16
- DOI
  10.1074/jbc.m110.179382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590628, KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy2011
- Author(s)
  Tominaga T., et al
- Journal Title
  
  J Biol Chem
  
  Volume: 286(22) Pages: 20109-20116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390169
[Journal Article] Transcription factor 7-like 2(TCF7L2) regulates activin receptor-like kinase 1(ALK1)/ Smad1 pathway for development of diabetic nephropathy2010
- Author(s)
  Araoka T, Abe H, Tominaga T, Mima A, Matsubara T, Murakami T, Kishi S, Nagai K, Doi T
- Journal Title
  
  Mol Cells
  
  Volume: 30(3) Issue: 3 Pages: 209-218
- DOI
  10.1007/s10059-010-0109-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
[Journal Article] Trophoblast glycoprotein : possible candidate mediating podocyte injuries in glomerulonephritis2010
- Author(s)
  Murakami T, Abe H, Nagai K, Tominaga T, Takamatsu N, Matsubara T, Araoka T, Kishi S, Takahashi T, Mima A, Takai Y, Kopp JB, Doi T.
- Journal Title
  
  Am J Nephrol
  
  Volume: 32(6) Issue: 6 Pages: 505-521
- DOI
  10.1159/000321366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591032, KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-22390169
[Presentation] 腎硬化症における小胞体ストレス分子メカニズムの解析2022
- Author(s)
  若林龍矢, 櫻井明子, 越智ありさ, 冨永辰也
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08593
[Presentation] 高吸水性ポリマーを用いた新規エクソソーム精製法2022
- Author(s)
  越智ありさ, 櫻井明子, 太田浩二, 飛永恭兵, 若林龍矢,脇野修, 右手浩一, 冨永辰也
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08593
[Presentation] 小胞体ストレス誘導下における腎線維化とBMP4/CHOPの機能解析2022
- Author(s)
  若林龍矢、櫻井明子、越智ありさ、冨永辰也
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] 腎硬化症における小胞体ストレス分子メカニズムの解析2022
- Author(s)
  若林龍矢、櫻井明子、越智ありさ、冨永辰也
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] 高吸水性ポリマーを用いた新規エクソソーム精製法2022
- Author(s)
  越智ありさ、櫻井明子、太田浩二、飛永恭兵、若林龍也、脇野修、右手浩一、冨永辰也
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] 腎脂質代謝異常とERストレスの作用機序について「ApoE欠損動脈硬化症モデルマウスでの検討」2022
- Author(s)
  宮城将展, 若林龍矢, 櫻井明子, 冨永辰也
- Organizer
  第46回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-20K08593
[Presentation] 血管内皮特異的BMP4発現マウスへの高脂肪食負荷による影響について2021
- Author(s)
  田村花菜子、若林龍矢、櫻井明子、冨永辰也
- Organizer
  第45回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-20K08593
[Presentation] 血管内皮特異的BMP4発現マウスへの高脂肪食負荷による影響について2021
- Author(s)
  田村花菜子、若林龍矢、櫻井明子、冨永辰也
- Organizer
  徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] 腎線維化病変発症機序の解析2021
- Author(s)
  若林龍矢、田村花菜子、櫻井明子、冨永辰也
- Organizer
  第45回徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-20K08593
[Presentation] 腎繊維化病変発症機序の解析2021
- Author(s)
  若林龍矢、田村花菜子、櫻井明子、冨永辰也
- Organizer
  徳島県医学検査学会
- Data Source
  KAKENHI-PROJECT-21K07367
[Presentation] P16は糸球体内皮細胞においてTGF-b刺激により核内移行する2021
- Author(s)
  上田紗代、長井幸二郎、冨永辰也、越智ありさ、西村賢二、柴田恵理子、田蒔昌憲、安部秀斉
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08705
[Presentation] Mesangial Matrix Expansion Attenuated by All-Trans Retinoic Acid Through Direct Suppression of Bone Morphogenetic Protein 4 in Mouse Diabetic Nephropathy2018
- Author(s)
  Masanori Tamaki、Tatsuya Tominaga、Yui Fujita、Seiji Kishi、Taichi Murakami、Kojiro Nagai、Hideharu Abe、Toshio Doi
- Organizer
  KIDNEY WEEK 2018 American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09619
[Presentation] Palovarotene, selective retinoic receptor-γ agonist, inhibited both BMP4 and TGF-β signaling pathways in diabetic nephropathy2017
- Author(s)
  Yui Fujita, Tatsuya Tominaga, Masanori Tamaki, Taichi Murakami, Seiji Kishi, Kojiro Nagai, Hideharu Abe, Toshio Do1
- Organizer
  The American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09700
[Presentation] Palovarotene, Selective Retinoic Receptor-γ Agonist, Inhibited Both BMP4 and TGF-β Signaling Pathways in Diabetic Nephropathy2017
- Author(s)
  Yui Fujita, Tatsuya Tominaga, Masanori Tamaki, Taichi Murakami, Seiji Kishi, Kojiro Nagai, Hideharu Abe, Toshio Doi
- Organizer
  KIDNEY WEEK 2017 American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09619
[Presentation] The role of BMP4 signal pathway on the glomerulosclerosis.2017
- Author(s)
  Tatsuya Tominaga, Yui Fujita, Taichi Murakami, Seiji Kishi, Kojiro Nagai, Hideharu Abe, Toshio Doi
- Organizer
  Keystone symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09700
[Presentation] Glomerulosclerosis Attenuated by Retinoic Acid through Bone Morphogenetic Protein 4 Suppression in Mice with Streptozotocin-Induced Diabetes2017
- Author(s)
  Masanori Tamaki, Tatsuya Tominaga, Yui Fujita, Seiji Kishi, Taichi Murakami, Kojiro Nagai, Hideharu Abe, Toshio Doi
- Organizer
  KIDNEY WEEK 2017 American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09619
[Presentation] レチノイン酸による糖尿病性糸球体硬化分子BMP4制御機構の検討2017
- Author(s)
  田蒔昌憲、冨永辰也、藤田結衣、松浦元一、岸誠司、村上太一、長井幸二郎、安部秀斉、土井俊夫
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09619
[Presentation] In vivo evidence of mTORC1-S6 kinase pathway involvement in the development of glomerulosclerosis in　human IgA nephropathy2016
- Author(s)
  Kojiro Nagai, Tatsuya Tominaga, Taichi Murakami, Eriko Shibata, Seiji Kishi, Motokazu Matsuura, Hideharu Abe, Toshio Doi
- Organizer
  KIDNEY WEEK 2016 American Society of Nephrology
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09619
[Presentation] メサンギウム細胞のin vivoでの機能解析～mTOR経路の活性化は糸球体硬化を誘導する～2016
- Author(s)
  長井　幸二郎、冨永　辰也、村上　太一、柴田　恵理子、岸　誠司、松浦　元一、安部　秀斉、土井　俊夫
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K09619
[Presentation] BMP4 regulates podocyte injury in the diabetic nephropathy2012
- Author(s)
  Tominaga T. et al.
- Organizer
  American Society of Nephrology, Kidney Week 2012
- Place of Presentation
  San Diego Convention Center(USA)
- Data Source
  KAKENHI-PROJECT-22390169
[Presentation] Role of BMP4 for regulating podocyte injury in the diabetic nephropathy2012
- Author(s)
  Tominaga T. el al.
- Organizer
  American Society for Cell biology
- Place of Presentation
  The Moscone Center(USA)
- Data Source
  KAKENHI-PROJECT-22390169
[Presentation] 糸球体腎炎におけるCD44作用機序の解析2012
- Author(s)
  金井麻衣、冨永辰也、安部秀斉、美馬晶、林早苗、長井幸二郎、土井俊夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] BMP4における糖尿病性腎症の発症とアルブミン尿排泄に関する新たな機序2011
- Author(s)
  冨永辰也, ら
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌市さっぽろ芸術文化の館(旧北海道厚生年金会館)・札幌市教育文化会館・ロイトン札幌・札幌プリンスホテル国際館パミール・東京ドームホテル札幌(旧札幌後楽園ホテル)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22390169
[Presentation] Genomic biomarkerを用いたCKD患者の心血管リスク評価の試み2011
- Author(s)
  吉川和寛、安部秀斉、冨永辰也、岸誠司、近藤直樹、松浦元一、長井幸二郎、土井俊夫、中村雅将、土田健司、水口潤、川島周
- Organizer
  第56回日本透析医学会学術集会・総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590628
[Presentation] 糖尿病性腎症発症とアルブミン尿排泄に関与するBMP4の分子機構2011
- Author(s)
  冨永辰也, ら
- Organizer
  第52回日本生化学会中国・四国支部総会
- Place of Presentation
  広島市広島大学・広仁会館
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22390169
[Presentation] 尿中エクソゾームを用いた慢性腎臓病の非侵襲的診断法と予後予測2011
- Author(s)
  林早苗、安部秀斉、冨永辰也、安部尚子、近藤直樹、土井俊夫
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市
- Data Source
  KAKENHI-PROJECT-21590628
[Presentation] Trophoblast glycoprotein regulates the podocyte injuries in experimental glomerulonephritis2011
- Author(s)
  Murakami T, Abe H, Nagai K, Tominaga T, Matsuura M, Kishi S, Kishi F, Yoshikawa K, Kondo N, Jeffrey Kopp, Doi T
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-21591032
[Presentation] 糖尿病性腎症発症とアルブミン尿排泄に関与するBMP4の分子機構2011
- Author(s)
  冨永辰也, ら
- Organizer
  第52回日本生化学会中国・四国支部総会
- Place of Presentation
  広島大学・広仁会館(広島市)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-21590628
[Presentation] 尿中エクソゾームを用いた慢性腎臓病の非侵襲的診断法と予後予測2011
- Author(s)
  林早苗、安部秀斉、冨永辰也、安部尚子、近藤直樹、土井俊夫
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23659445
[Presentation] CKD患者の血中MGPおよび関連分子と、病態に関する検討2010
- Author(s)
  吉川和寛、安部秀斉、冨永辰也、岸誠司、岸史、荒岡利和、村上太一、近藤直樹、松浦元一、長井幸二郎、土井俊夫、中村雅将、土田健司、水口潤、川島周
- Organizer
  第55回日本透析医学会学術集会・総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590628
[Presentation] BMP4/ Smad1 Signaling Is a Critical Therapeutic Target for Diabetic Nephropathy2010
- Author(s)
  Matsubara T, Abe H, Ueda O, Tominaga T, Mima A, Nagai K, Torikoshi K, Araki M, Goto C, Kinosaki M, Jishage K, Fukushima N, Iehara N, Fukatsu A, Arai H, Doi T
- Organizer
  43^<rd> American Society of Nephrology(ASN) Annual
- Place of Presentation
  Meeting, Denver
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21590628
[Presentation] The Novel Function of Trophoblast Glycoprotein(Tpbg) on Actin Remodeling in Podocyte Injured in Experimental Glomerulonephritis2009
- Author(s)
  Murakami T, Abe H, Matsuura M, Araoka T, Kishi S, Tominaga T, Shigeta R, Yoshikawa K, Kishi F, Takamatsu N, Takahashi T, Mima A, Nagai K, Takai Y, Doi T
- Organizer
  American Society of Nephrology(ASN) Annual Meeting
- Place of Presentation
  Pennsylvania, U.S.A.
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21591032
[Presentation] 糖尿病性腎症発症とアルブミン尿排泄に関与するBMP4の分子機構
- Author(s)
  冨永辰也
- Organizer
  第52回日本生化学会中国・四国支部総会
- Place of Presentation
  広島大学・広仁会館(広島市)
- Data Source
  KAKENHI-PROJECT-21590628
[Presentation] BMP4 regulates podocyte injury in the diabetic nephropathy
- Author(s)
  Tominaga T. el al.
- Organizer
  The American Diabetes Association’s 72nd Scientific Sessions
- Place of Presentation
  Philadelphia Convention Center(USA)
- Data Source
  KAKENHI-PROJECT-22390169

1. ABE Hideharu (60399342)

# of Collaborated Projects: 6 results

# of Collaborated Products: 13 results
2. NAGAI Kojiro (40542048)

# of Collaborated Projects: 6 results

# of Collaborated Products: 14 results
3. MATSUURA Motokazu (10403734)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
4. SAKURAI Akiko (70707900)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
5. 田蒔昌憲 (90528902)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. DOI Toshio (60183498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. KISHI Seiji (10519507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. 村上太一 (30403736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. KONDO Naoki (80522789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. MIMA Akira (00432401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 池田康将 (60432754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 寺町順平 (20515986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 原田武志 (10618359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 日浅雅博 (90511337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 沢禎彦 (70271666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 脇野修 (50265823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 長谷川一宏 (30424162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 藤田結衣 (30837266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MATSUBARA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 荒井秀典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 家原典之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tominaga Tatsuya 冨永 辰也

TOMINAGA Tatsuya 冨永 辰也

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Elucidation of the molecular mechanisms responsible for the recent increase in DKDPrincipal Investigator

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Development of new CKD therapeutic agent targeting cytokine processing enzymePrincipal Investigator

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慢性腎臓病(CKD)における糖尿病血管合併症の成因解明Principal Investigator

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Tominaga Tatsuya 冨永辰也

TOMINAGA Tatsuya 冨永辰也