TAKAKUBO Yuya 高窪祐弥

… Alternative Names

高窪祐弥タカクボユウヤ

Less

Researcher Number	80431641
Other IDs
Affiliation (Current)	2025: 山形大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 山形大学, 医学部, 准教授 2017 – 2020: 山形大学, 医学部, 准教授 2013 – 2016: 山形大学, 医学部, 講師 2015: 山形大学, 医学部・整形外科学講座, 講師 2012 – 2013: 山形大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 自然免疫 / 関節リウマチ / 薬剤反応性 / 免疫学 / 薬剤抵抗性 / グレード分類 / 疾患活動性 / 炎症性サイトカイン / 炎症性免疫担当細胞 / 獲得免疫 … More / 制御性免疫 / Toll様受容体 / 薬剤耐性 / 国際情報交換 / toll 様受容体 / サイトカイン / 形質細胞様樹状細胞 / リウマチ / Toll-like receptor / 樹状細胞 / 微小粒子 … More Except Principal Investigator 自然免疫 / 人工関節 / オートファジー / 人工関節周囲感染 / マクロファージ / インプラント感染症 / Toll様受容体 / ネトーシス / 滑膜炎 / 生体反応 / 感染 / インプラント感染 / 選択的オートファジー / 自然免疫受容体 / 人工関節インプラント感染症 / 変形性関節症 / 関節リウマチ / 炎症性滑膜組織 / 人工関節感染 / Nod様受容体 / 予後予測因子 / 変異型イソクエン酸デヒドロゲナーゼ / イソクエン酸脱水素酵素 / 骨肉腫 / 非感染性骨溶解 / NOD様受容体 / osteolysis / NOD-like receptor / Toll-like receptor / 感染性人工関節 / Total hip arthropasty / Osteolysis / Aseptic loosening / NLR / TLR / 人工股関節の弛み Less

人工関節周囲感染の制御に向けたマクロファージによる細胞治療の基礎研究
- Principal Investigator
  
  高木理彰
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Yamagata University
Innate immune receptor and alternative autophagy in pathogenesis of prosthetic joint infection
- Principal Investigator
  
  Takagi Michiaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Yamagata University
The role of innate immunology in the patients with early rheumatoid arthritis and resistant-anti rheumatic drugsPrincipal Investigator
- Principal Investigator
  
  Takakubo Yuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Innate immunity reaction in marcophage for periprosthetic joint infection
- Principal Investigator
  
  Takagi Michiaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Relationship between expression of isocitrate dehydrogenase and clinical outcomes in patients with osteosarcoma
- Principal Investigator
  
  tsuchiya takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Analyses of innate immune sensors, TLR and NLR, in periprosthetic infection.
- Principal Investigator
  
  TAKAGI Michiaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Does microparticles induce innate immunity with stimulation plasmacytoid dendritic cells in rheumatic diseases?Principal Investigator
- Principal Investigator
  
  TAKAKUBO Yuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University

All 2023 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰
- Total Pages
  9
- Publisher
  Pharma Medica
- Data Source
  KAKENHI-PROJECT-17K10995
[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰
- Total Pages
  9
- Publisher
  Pharma Medica
- Data Source
  KAKENHI-PROJECT-15K10459
[Book] Bio-tribocorrosion in biomaterials and medical implants2013
- Author(s)
  Tan Y, Takakubo Y, et al.
- Total Pages
  542
- Publisher
  Woodhead Publisher
- Data Source
  KAKENHI-PROJECT-24791522
[Book] Book of Bio-tribocorrosion in biomaterials and medical implants, Wear-corrosion mechanisms. In: 9. LOOSENING OF TOTAL JOINT REPLACEMENT,2013
- Author(s)
  Takakubo Y, Berce A, Tamaki A, Milosev I, Al-Samadi A, Tiainen VM, Sillat T, Konttinen YT
- Total Pages
  432
- Publisher
  Woodhead Publisher
- Data Source
  KAKENHI-PROJECT-24592252
[Book] Recent Advances in Arthroplasty: What we know about the physiological reactions of the local tissue on the prosthesis and its wear products2012
- Author(s)
  Konttinen YT, Takagi M, Takakubo Y, et al
- Total Pages
  614
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24592252
[Book] Wear of orthopaedic implants and artificial joints: Materials used for hip and knee implants. Saverio A (Ed.), In: Wear of orthopaedic implants and artificial joints.2012
- Author(s)
  Takakubo Y, Konttinen YT, Takagi M, et al
- Publisher
  Woodhead Publishing
- Data Source
  KAKENHI-PROJECT-24592252
[Book] Infected Total Joint Arthroplasty: Biomaterial-host interactions in aseptic and septic conditions, In: Infected total joint arthroplasty. The algorithmic approach2012
- Author(s)
  Takakubo Y, Takagi M, Konttinen YT, et al
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24592252
[Book] Recent Advances in Arthroplasty: Does it exist something like long-term tolerance to an implant? Aseptic loosening of total hip arthroplasty as a result of local failure of tissue homeostasis.2012
- Author(s)
  Takakubo Y, Konttinen YT, Takagi M, et al
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24592252
[Book] Recent Advances in Arthroplasty: Cytokines and orchestrating of local adverse reaction to prosthetic particles. Aseptic loosening of total hip arthroplasty as a result of local failure of tissue homeostasis.2012
- Author(s)
  Takakubo Y, Takagi M, Konttinen Y, et al
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Friend or foe? Inflammation and the foreign body response to orthopedic biomaterials2023
- Author(s)
  Gibon Emmanuel、Takakubo Yuya、Zwingenberger Stefan、Gallo Jiri、Takagi Michiaki、Goodman Stuart B.
- Journal Title
  
  Journal of Biomedical Materials Research Part A
  
  Volume: 1 Issue: 8 Pages: 1-16
- DOI
  10.1002/jbm.a.37599
- Data Source
  KAKENHI-PROJECT-22K09299
[Journal Article] Comparative study of HO-1 expressing synovial lining cells between RA and OA2020
- Author(s)
  Yang Suran、Ohe Rintaro、Aung Naing Ye、Kato Tomoya、Kabasawa Takanobu、Utsunomiya Aya、Takakubo Yuya、Takagi Michiaki、Yamakawa Mitsunori
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 1 Pages: 1-8
- DOI
  10.1080/14397595.2019.1704976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16577, KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K08736, KAKENHI-PROJECT-17K10995
[Journal Article] 生物学的製剤使用関節リウマチ患者における整形外科手術の検討.2019
- Author(s)
  高窪祐弥, 大木弘治, 長沼靖、梁秀蘭、高木理彰
- Journal Title
  
  関節の外科
  
  Volume: 45 Pages: 101-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10995
[Journal Article] Rapid disappearing of gouty tophi of foot due to reducing urate pool by resection of huge gouty tophi of opposite foot in the patient with hyperuricemia; a case of report.2019
- Author(s)
  Takakubo Y, Imamura Y, Tezuka H, Okada S, Naganuma Y, Ito J, Sugawara M, Yang S, Oki H, Sasaki A, Sasaki K, Takagi M
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 4 Issue: 1 Pages: 1-6
- DOI
  10.1080/24725625.2019.1680135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K10995
[Journal Article] Assessing an alpha-defensin lateral flow device for diagnosing septic arthritis: reporting on a false-negative case and a false-positive case.2019
- Author(s)
  2.Narita A, Suzuki A, Nakajima T, Takakubo Y, Ito J, Sasaki A, Takagi M
- Journal Title
  
  Modern Rheumatology Case Reports.
  
  Volume: 4 Issue: 1 Pages: 156-160
- DOI
  10.1080/24725625.2019.1683134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-18H02917
[Journal Article] Disassembly of bilateral bipolar heads within 10 years after hip hemiarthroplasties for avascular necrosis of femoral heads: a case report.2019
- Author(s)
  Ito J, Takakubo Y, Monma R, Oki H, Sasaki K, Takagi M
- Journal Title
  
  Modern Rheumatology Case Reports.
  
  Volume: 4 Issue: 1 Pages: 147-151
- DOI
  10.1080/24725625.2019.1662596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K10995
[Journal Article] intestinal immunity and flora in a collagen-induced mouse parthritis model: differences during arthritis progression.2019
- Author(s)
  Nemoto N, Takeda Y, Nara H, Araki A, Gazi Y, Takakubo Y, Naganuma Y, Takagi M, Asao H
- Journal Title
  
  Int Immunol.
  
  Volume: 32 Issue: 1 Pages: 49-56
- DOI
  10.1093/intimm/dxz058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-18K16644
[Journal Article] Activation of plasmacytoid dendritic cells by apoptotic particles - mechanism for the loss of immunological tolerance in Sjögren's syndrome.2018
- Author(s)
  Ainola M, Porola P, Takakubo Y, Przybyla B, Kouri VP, Tolvanen TA, Hänninen A, Nordström DC.
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 191 Issue: 3 Pages: 301-310
- DOI
  10.1111/cei.13077
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459, KAKENHI-PROJECT-17K10995
[Journal Article] Immunohistochemical Analysis of Inflammatory Rheumatoid Synovial Tissues Using Anti-Human Podoplanin Monoclonal Antibody Panel.2018
- Author(s)
  Suzuki T, Takakubo Y, Oki H, Liu X, Honma R, Naganuma Y, Goodman SB, Kaneko MK, Kato Y, Takagi M.
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother.
  
  Volume: 37 Issue: 1 Pages: 12-19
- DOI
  10.1089/mab.2017.0047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10459, KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-18H02917
[Journal Article] The Incidence of Atypical Femoral Fractures in Patients with Rheumatic Disease: Yamagata Prefectural Committee of Atypical Femoral Fractures (YamaCAFe) Study2017
- Author(s)
  Takakubo Y, et al.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 242 Issue: 4 Pages: 327-334
- DOI
  10.1620/tjem.242.327
- NAID
  130006067688
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-15K10459
[Journal Article] Distribution of podoplanin in synovial tissues in rheumatoid arthritis patients using biologic or conventional disease-modifying anti-rheumatic drugs.2017
- Author(s)
  Takakubo Y, Oki H, Naganuma Y, Sasaki K, Sasaki A, Tamaki Y, Suran Y, Konta T, Takagi M
- Journal Title
  
  Curr Rheumatol Rev
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] Danger of frustrated sensors: Role of TLR and NOD-like receptors in aseptic and septic inflammations around failed total hip replacements2017
- Author(s)
  Takagi M, Takakubo Y, et al.
- Journal Title
  
  J Orthop Translat
  
  Volume: 10 Pages: 68-85
- DOI
  10.1016/j.jot.2017.05.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Journal Article] Danger of frustrated sensors: Role of Toll-like receptors and NOD-like receptors in aseptic and septic inflammations around total hip replacements.2017
- Author(s)
  Takagi M, Takakubo Y, Pajarinen J, Naganuma Y, Oki H, Masahiro M, Goodman S
- Journal Title
  
  J Orthop Translat
  
  Volume: 10 Issue: 3 Pages: 1-8
- DOI
  10.1016/j.jos.2018.01.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459, KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-18H02917
[Journal Article] Distribution of podoplanin in synovial tissues in rheumatoid arthritis patients using biologic or conventional disease-modifying anti-rheumatic drugs.2017
- Author(s)
  Takakubo Y, et al.
- Journal Title
  
  Curr Rheumatol Rev.
  
  Volume: 13 Issue: 1 Pages: 72-78
- DOI
  10.2174/1573397112666160331143607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10995
[Journal Article] Comparison of the Effects of Osteochondral Autograft Transplantation With Platelet-Rich Plasma or Platelet-Rich Fibrin on Osteochondral Defects in a Rabbit Model.2017
- Author(s)
  Maruyama M, Takakubo Y, et al.
- Journal Title
  
  Am J Sports Med.
  
  Volume: 45 Issue: 14 Pages: 3280-3288
- DOI
  10.1177/0363546517721188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-15K10459
[Journal Article] 精神疾患を有する患者に対する人工股関節全置換術の周術期合併症と短期成績2016
- Author(s)
  竹内隆二, 佐々木幹, 高窪祐弥, 伊藤重治, 平山朋幸, 大木弘治, 高木理彰
- Journal Title
  
  Hip joint
  
  Volume: ４２ Pages: 944-946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes.2016
- Author(s)
  Naganuma Y, Takakubo Y, Takagi M, et al
- Journal Title
  
  Journal of Biomedical Material and Research A
  
  Volume: 104 Issue: 2 Pages: 435-444
- DOI
  10.1002/jbm.a.35581
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] 過去11年間の人工股関節手術件数の推移 -当院と関連病院の傾向と特徴-2016
- Author(s)
  高窪祐弥, 伊藤重治, 佐々木幹, 平山朋幸, 大木弘治, 門馬亮介, 玉木康信, 川路博之, 小林真司, 石井政次, 高木理彰
- Journal Title
  
  Hip joint
  
  Volume: 42 Pages: 912-914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] トシリズマブ使用関節リウマチ患者における人工関節手術の検討2016
- Author(s)
  高窪祐弥, 大石隆太, 伊藤重治, 長沼靖, 梁秀蘭, 佐々木明子, 佐々木幹, 大類広, 高木理彰
- Journal Title
  
  日人工関節会誌
  
  Volume: 46 Pages: 633-634
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] 過去10年間の関節リウマチ患者に対するメソトレキセート投与量の経年的変化と重篤な有害事象の発生率2015
- Author(s)
  高窪祐弥, 結城北斗, 金野昇, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 佐々木幹, 大類広, 高木理彰
- Journal Title
  
  日本関節病学会誌
  
  Volume: 34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] PJIの病理組織学的検討.2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Journal Title
  
  関節外科
  
  Volume: 34 Pages: 35-41
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] リウマチ性疾患における微小粒子と形質細胞様樹状細胞の検討2015
- Author(s)
  高窪祐弥, 佐々木幹, 梁秀蘭, 大木弘治, 長沼靖, 佐々木明子, 大類広, 高木理彰
- Journal Title
  
  日本関節病学会誌
  
  Volume: 34
- NAID
  130005255850
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 過去10年間の人工関節手術件数の推移-当院と関連病院の傾向と特徴-2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Journal Title
  
  日本人工関節会誌
  
  Volume: 45 Pages: 773-774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] Role of innate immune sensors, TLRs and NLRP3, in rheumatoid arthritis and osteoarthritis.2014
- Author(s)
  Takakubo Y, Barreto G, Konttinen YT, Oki H, Takagi M
- Journal Title
  
  Journal of Long-Term Effects of Medical Implants
  
  Volume: 24 Issue: 4 Pages: 243-251
- DOI
  10.1615/jlongtermeffmedimplants.2014011295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] 大径骨頭金属対金属摺動面人工股関節の中間成績2014
- Author(s)
  平山朋幸, 佐々木幹, 高窪祐弥, 高木理彰
- Journal Title
  
  日本人工関節学会誌
  
  Volume: 44 Pages: 389-390
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] 過去10年間の高齢者不安定型骨盤輪損傷症例の検討2014
- Author(s)
  高窪祐弥, 佐々木幹, 大木弘治, 平山朋幸, 赤羽武, 和根崎禎大, 高木理彰, 玉木康信, 川路博之, 石井政次, 小林真司
- Journal Title
  
  Hip Joint
  
  Volume: 40 Pages: 466-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Role of innate immune sensors, TLRs and NLRP3, in rheumatoid arthritis and osteoarthritis.2014
- Author(s)
  Takakubo Y, Barreto G, Konttinen YT, Oki H, Takagi M
- Journal Title
  
  Journal of Long-Term Effects of Medical Implants
  
  Volume: 24 Pages: 243-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Cell - tissue interactions in osteoarthritic human hip joint articular cartilage.2014
- Author(s)
  Huttu MRJ, Puhakka J, Makela JTA, Takakubo Y, Tiitu V, Saarakkala S, Konttinen YT, Kiviranta I, Korhonen RK
- Journal Title
  
  Connect Tissue Res
  
  Volume: 55 Issue: 4 Pages: 282-291
- DOI
  10.3109/03008207.2014.912645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252, KAKENHI-PROJECT-24791522
[Journal Article] Macrophage polarization and activation in response to implant debris: influence by "Particle Disease" and "Ion Disease".2014
- Author(s)
  Konttinen YT, Jukka P, Takakubo Y, Jiri G, Christophe N, Takagi M, Goodman SB
- Journal Title
  
  Journal of Long-Term Effects of Medical Implants
  
  Volume: 24 Issue: 4 Pages: 267-281
- DOI
  10.1615/jlongtermeffmedimplants.2014011355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Macrophage polarization and activation in response to implant debris: influence by "particle disease" and "ion disease"2014
- Author(s)
  Konttinen YT, Pajarinen J, Takakubo Y, Gallo J, Nich C, Takagi M, Goodman SB
- Journal Title
  
  J Long Term Eff Med Implants
  
  Volume: 24 Pages: 267-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 山形地区における循環型関節リウマチ病診連携ネットワーク (やらんなネット) の構築と問題点 –二人主治医制の導入を目指して-2014
- Author(s)
  高窪祐弥, 佐々木幹, 長沼靖, 梁秀蘭, 佐々木明子, 高木理彰
- Journal Title
  
  東日本整災会誌
  
  Volume: 26 Pages: 465-470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 過去10年間の関節リウマチ (RA)患者に対する人工関節手術件数の推移2014
- Author(s)
  高窪祐弥, 佐々木幹, 大木弘治, 平山朋幸, 成田淳, 浅野多聞, 玉木康信, 冨樫栄太, 川路博之, 福島重宣, 石井政次, 高木理彰
- Journal Title
  
  日本人工関節学会誌
  
  Volume: 44 Pages: 741-742
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Inflammatory immune cell responses and Toll-like receptor expression in synovial tissues in rheumatoid arthritis patients treated with biologics or DMARDs.2013
- Author(s)
  Takakubo Y, Tamaki Y, Hirayama T, Iwazaki K, Sasaki K, Sasaki A, Takakubo N, Konttinen YT, Takagi M
- Journal Title
  
  Clin Rheumatol
  
  Volume: 32 Pages: 853-861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] 生物学的製剤使用下でのリウマチ手術の検討2013
- Author(s)
  高窪祐弥ら
- Journal Title
  
  関節の外科
  
  Volume: 40 Pages: 77-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Macrophages-Key cells in the response to wear debris from joint replacements2013
- Author(s)
  Nich C, Takakubo Y, Pajarinen J, Ainola M, Salem A, Sillat T, Rao AJ, Raska M, Tamaki Y, Takagi M, Konttinen YT, Goodman SB, Gallo J
- Journal Title
  
  J Biomed Mater Res A
  
  Volume: 101 Pages: 3033-3045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] 感染症関連関節炎による足関節障害に対し人工足関節置換術を施行した１例2013
- Author(s)
  高窪祐弥ら
- Journal Title
  
  日本人工関節学会誌
  
  Volume: 43 Pages: 737-738
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Osteogenesis of human mesenchymal stem cells on micro-patterned surfaces2013
- Author(s)
  Kaivosoja E, Myllymaa S, Takakubo Y, Korhonen H, Myllymaa K, Konttinen YT, Lappalainen R, Takagi M
- Journal Title
  
  J Biomater Appl
  
  Volume: 27 Pages: 862-871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Macrophages-Key cells in the response to wear debris from joint replacements2013
- Author(s)
  Nich C, Takakubo Y, et al.
- Journal Title
  
  J Biomed Mater Res A
  
  Volume: 101 Issue: 10 Pages: 3033-3045
- DOI
  10.1002/jbm.a.34599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 人工股関節手術後の大腿骨ステム周囲骨折2013
- Author(s)
  高窪祐弥ら
- Journal Title
  
  東日本整誌
  
  Volume: 25 Pages: 152-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Inflammatory immune cell responses and Toll-like receptor expression in synovial tissues in rheumatoid arthritis patients treated with biologics or DMARDs2013
- Author(s)
  Takakubo Y, et al.
- Journal Title
  
  Clinical Rheumatology
  
  Volume: 32 Issue: 6 Pages: 853-861
- DOI
  10.1007/s10067-013-2209-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 人工関節の感染2013
- Author(s)
  高窪祐弥ら
- Journal Title
  
  リウマチ科
  
  Volume: 50 Pages: 224-232
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 人工股関節再置換術術後におけるVancouver分類 type B-1大腿骨ステム周囲骨折に対する保存的治療2013
- Author(s)
  高窪祐弥ら
- Journal Title
  
  東北整災誌
  
  Volume: 56 Pages: 34-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Takakubo Y, Yrjö T. Konttinen: Immune-Regulatory Mechanisms in Systemic Autoimmune and Rheumatic Diseases.2012
- Author(s)
  Yuya Takakubo, et al.
- Journal Title
  
  Clin Devlop Immunology
  
  Volume: 941346 Pages: 941346-941346
- DOI
  10.1155/2012/941346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 当院における不安定性骨盤輪損傷の治療成績2012
- Author(s)
  佐々木幹、高木理彰、高窪祐弥、大木弘治、小林真司
- Journal Title
  
  Hip Joint
  
  Volume: 38 Pages: 668-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] リウマチ性疾患のジャクー関節症における病理組織学的検討.2012
- Author(s)
  高窪祐弥、佐々木明子、高木理彰
- Journal Title
  
  関節の外科
  
  Volume: 39 Pages: 19-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] RANKL in the loosening of total ankle replacement implants2012
- Author(s)
  H. Koivu, Z. Mackiewicz, Y. Takakubo, et al.
- Journal Title
  
  Bone
  
  Volume: 51 Issue: 3 Pages: 546-52
- DOI
  10.1016/j.bone.2012.05.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Midterm clinico-radiologic findings of an open label observation study of add on tacrolimus with biologics or non-biologic DMARDs2012
- Author(s)
  Yuya Takakubo, et al.
- Journal Title
  
  Rheumatology International Rheumatol Int
  
  Volume: 32 Pages: 3487-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] 自然免疫センサー（2）. Toll-like receptor (TLR)をはじめとする分子群.2012
- Author(s)
  玉木康信、高窪祐弥、平山朋幸、高木理彰
- Journal Title
  
  整形外科
  
  Volume: 63 Pages: 660-660
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Minocycline-induced periarticular black bone in patients with inflamed joints who have undergone total arthroplasties; five case report and review of the literature.2012
- Author(s)
  Yang S, Takakubo Y, Sasaki K, Takagi M, et al
- Journal Title
  
  Clin Orthop Surg
  
  Volume: 4 Issue: 3 Pages: 181-187
- DOI
  10.4055/cios.2012.4.3.181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] 自然免疫センサー（1）. Toll-like receptor (TLR)をはじめとする分子群.2012
- Author(s)
  玉木康信、高窪祐弥、平山朋幸、高木理彰
- Journal Title
  
  整形外科
  
  Volume: 63 Pages: 570-570
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Minocycline-induced periarticular black bones in inflamed joints underwent arthroplastic reconstruction2012
- Author(s)
  Yang S, Takakubo Y, et al.
- Journal Title
  
  Clin Orthop Surg
  
  Volume: 3 Pages: 181-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791522
[Journal Article] Mid-term clinico-radiologic findings of an open label observation study of add on tacrolimus with biologies or non-biologic DMARDs2011
- Author(s)
  Takakubo Y, Tamaki Y, Takagi M, et al.
- Journal Title
  
  Rheumatology International
  
  Volume: (Epub ahead of print) Issue: 11 Pages: 3487-3494
- DOI
  10.1007/s00296-011-2200-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591929, KAKENHI-PROJECT-24592252
[Journal Article] Osteogenesis of human mesenchymal stem cells on micro-patterned surfaces2011
- Author(s)
  Takakubo Y, Konttinen YT, Takagi M, et al.
- Journal Title
  
  J Biomater Appl
  
  Volume: (Epub ahead of print) Issue: 7 Pages: 862-871
- DOI
  10.1177/0885328211428094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591929, KAKENHI-PROJECT-24592252, KAKENHI-PROJECT-24791522
[Presentation] Analysis on autophagy-related molecules in macrophage subtype in the synovium of rheumatoid arthritis and　Osteoarthritis2023
- Author(s)
  Huang H, Takakubo Y, Maruyama M, Uno T, Akabane T, Igarashi T, Liu X, Takeda Y, Goodman SB, Takagi M
- Organizer
  ORS 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09299
[Presentation] Autophagy-related molecules and structures in the synovium of rheumatoid arthritis and osteoarthritis.2020
- Author(s)
  Hanqing Huang, Xing Liu1, Yuya Takakubo, Tomohiro Uno, Takeru Akabane, Masahiro Maruyama, Stuart B. Goodman, Michiaki Takagi
- Organizer
  The 64th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, Nagoya
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Analysis on autophagy-related molecules and structures of the capsular tissues in periprosthetic joint infection2020
- Author(s)
  Xing Liu, Hanqing Huang, Yuya Takakubo, Tomohiro Uno, Takeru Akabane, Masahiro Maruyama, Stuart B. Goodman, Michiaki Takagi
- Organizer
  The 64th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology, Nagoya
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  1.Takakubo Y, Oki H, Yang S, Sasaki A, Sasaki K, Naganuma Y, KatoY, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Distribution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  Takakubo Y, Takagi M, et al.
- Organizer
  Orthopaedic Research Society 2019 Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A, Oki H, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Podoplanin is a potential biomarker in lipopolysaccharide-induced inflamed human fibroblast-like synoviocytes.2019
- Author(s)
  Suzuki T, Liu X, Takakubo Y, Oki H**, Honma R, Takagi M
- Organizer
  The 2nd International Combined Meeting of Orthopaedic Reserch Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Induction of podoplanin in synovial lining cell of lipopolysaccharide-induced rabbit arthritis model.2019
- Author(s)
  Honma R, Maruyama M, Liu X, Oki H, Takakubo Y, Takagi M
- Organizer
  The 2nd International Combined Meeting of Orthopaedic Reserch Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Rehabilitation of the salvege arthrodesis with bone auto- and allografts for failed total ankle arthroplasties in the patient with rheumatoid arthritis.2019
- Author(s)
  Takakubo Y, Narita A, Takano M, Suzuki Y, Sasaki K, Ito J, Sagae H, Kanauchi Y, Kobayashi S, Takagi M
- Organizer
  56th Annual Meeting of Japanese Association of Rehabilitation Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Rehabilitation of the salvege arthrodesis with bone auto- and allografts for failed total ankle arthroplasties in the patient with rheumatoid arthritis2019
- Author(s)
  Takakubo Y, Narita A, Takano M, Suzuki Y, Sasaki K**, Ito J, Sagae H**, Kanauchi Y**, Kobayashi S**, Takagi M
- Organizer
  56th Annual Meeting of Japanese Association of Rehabilitation Medicine
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Utility of alpha-defesin lateral flow device for periprosthetic joint onfection and septic arthritis.2019
- Author(s)
  Narita A, Suzuki A, Nakajima, Takakubo Y, Ito J, Yuki I, Oki H, Naganuma Y, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Distribution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  Takakubo Y, Oki H, Yang S, et al:
- Organizer
  ORS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Anti-tumor necrosis factor agents influence the apoptosis of inflammatory synovial cells in the patients with rheumatoid arthritis.2019
- Author(s)
  Takakubo Y, Suzuki Y, Yang S, Oki H, Takagi M
- Organizer
  The 2nd International Combined Meeting of Orthopaedic Reserch Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Distribution of immune-suppressive cells and Toll-like receptors in synovial tissues in the patients with rheumatoid arthritis which were treated by anti-TNF agents2019
- Author(s)
  Takakubo Y, Yang S, Suzuki Y, Oki H, Naganuma Y**, Sasaki A**, Sasaki K**, Orui H**, Takagi M
- Organizer
  The 63rd Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A**, Oki H**, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Podoplanin is a potential biomarker in lipopolysaccharide-induced inflamed human fibroblast-like synoviocytes.2019
- Author(s)
  Suzuki T, Liu X, Takakubo Y, Oki H, Honma R, Takagi M
- Organizer
  The 2nd International Combined Meeting of Orthopaedic Reserch Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A**, Oki H**, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Comparison of clinical features between subtrochanteric and diaphyseal atypical femoral fractures in our super-aging area.2019
- Author(s)
  Miyaji T, Takakubo Y, Ota D, Shibuya J, Oki H, Ito J, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Induction of podoplanin in synovial lining cell of lipopolysaccharide-induced rabbit arthritis model.2019
- Author(s)
  Honma R, Maruyama M, Liu X, Oki H, Takakubo Y, Takagi M
- Organizer
  The 2nd International Combined Meeting of Orthopaedic Reserch Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Utility of alpha-defesin lateral flow device for periprosthetic joint onfection and septic arthritis.2019
- Author(s)
  Narita A, Suzuki A, Nakajima, Takakubo Y, Ito J, Yuki I, Oki H, Naganuma Y, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Anti-tumor necrosis factor agents influence the apoptosis of inflammatory synovial cells in the patients with rheumatoid arthritis.2019
- Author(s)
  Takakubo Y, Suzuki Y, Yang S, Oki H, Takagi M
- Organizer
  The 2nd International Combined Meeting of Orthopaedic Reserch Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] The trend of revision total hip arthroplasties in super-aging area in last fourteen years.2019
- Author(s)
  Takakubo Y, Ito J, Oki H**, Momma R, Sasaki K**, Kawaji H**, Ishi M**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  Takakubo Y, Oki H, Yang S, Sasaki A, Sasaki K, Naganuma Y, KatoY, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] The relationship between sarcopenia and cognitive function in the patients with transaortic valve implantation.2019
- Author(s)
  Sasaki K, Murakawa M, Takakubo Y, Takagi M, Kouzuki M
- Organizer
  13th International Society of Physical and Rehabilitation Medicine World Congress,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Foot and ankle surgeries for the patients with rheumatoid arthritis in BIO-era.2018
- Author(s)
  Takakubo Y, Oki H, Sasaki K
- Organizer
  62th Annual Meeting of Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Toll-like receptors and immune-cells in rheumatoid synovial tissues treated by tocilizumab (TCZ)2018
- Author(s)
  Takakubo Y, Suzuki T, Oki H, et al
- Organizer
  4th Japan Society of Osteoimmunology
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] High-molecular-weight adiponectin is correlated with disease activity in the patients with rheumatoid arthritis.2018
- Author(s)
  Takakubo Y, Takagi M, et al.
- Organizer
  Orthopaedic Research Society 2018 Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Analysis of radiographic joint destruction in rheumatoid patients who have withdrawn, spaced and continued of biologics after achieving sustained remission from local biologics registry.2018
- Author(s)
  Takakubo Y, Nagai J, Naganuma Y, et al.
- Organizer
  European League Against Rheumatism 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Expression of inflammatory cytokines from plasmacytoid dendritic cells by stimulation of microparticles2018
- Author(s)
  Takakubo Y, Ainola M, Oki H, et al
- Organizer
  33th Annual Research Meeting of JOA
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Bone healing of atypical femoral fractures treated by teriparatide and/or low-intensity pulsed ultrasound therapy in patients with rthumatic diseases in north Japan.2018
- Author(s)
  Takakubo Y, Takagi M, et al.
- Organizer
  The 37th Scandinavian Congress of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] The trend of primary total hip arthroplasties for the patients with osteoarthritis in super-aging area in last thirteen years.2018
- Author(s)
  Takakubo Y, Ito J, Oki H, et al
- Organizer
  91th Annual Meeting of JOA
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Bone healing of atypical femoral fractures which were treated by teriparatide and low intensity pulsed ultrasound therapy in the patients with rheumatic diseases in the highly super aging area of North Japan.2018
- Author(s)
  Takakubo Y, Miyaji T, Ota D, et al.
- Organizer
  Scandinavian Congress of Rheumatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Infections are increased as the cause of revision total hip arthroplasties in the superaging area in northern Japan.2018
- Author(s)
  Takakubo Y, Takagi M, et al.
- Organizer
  EORS 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Changing of Orthopaedics Surgeries for the Patients with Rheumatoid Arthritis in BIO-era.2018
- Author(s)
  Takakubo Y, Ito J, Oki H, et al
- Organizer
  91th Annual Meeting of JOA
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Mid- and long-term results of revision THA with KT-plate for acetabular reconstruction.2018
- Author(s)
  Takakubo Y, Kawaji H, Ito J, et al
- Organizer
  91th Annual Meeting of JOA
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] The Value of Serum Interleukin-6 Before First Biologis Are Predicted to Clinical Response in The Patients of Rheumatoid Arthritis One Year After The Treatment.2018
- Author(s)
  Takakubo Y, Oki H, Sasaki K, et al:
- Organizer
  ORS 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Tumor necrosis factor inhibitors influence the apoptosis of inflammatory cells in rheumatoid synovial tissues.2018
- Author(s)
  Takakubo Y, Oki H, Sasaki K
- Organizer
  62th Annual Meeting of Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Infections are increased as the cause of revision total hip arthroplasties in the super-aging area in Northern Japan.2018
- Author(s)
  Takakubo Y, Ito J, Oki H, et al
- Organizer
  EORS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Trend of total hip arthroplasties in the super-aging area in Northern Japan.2017
- Author(s)
  Takakubo Y, Sasaki K, Ito J, Oki H, Honma R, Kawaji H, Ishii M, Takagi M
- Organizer
  ISTA 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Postoperative rehabilitation of atypical femoral fractures in patients with rheumatic diseases2017
- Author(s)
  Takakubo Y, Sasaki K, Narita Atsushi, Narita Aya, Kanauti Y, Yamakawa J, Sugawara M, Kobayashi S, Hanaka N, Takagi M
- Organizer
  The 54th Annual meeting of the Japanese association of rhehabilitation medicine
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] The incidence of atypical femoral fractures in patients with rheumatic disease in our prefectural area of north Japan in the suger-aging society: YamaCAFe study2017
- Author(s)
  Takakubo Y, Ohta D, Okuda S, Ito J, Oki H, Naganuma Y, Sasaki K, Ishii M, Takagi M
- Organizer
  The 90th Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] The incidence of atypical femoral fractures in patients with rheumatic disease in our prefectural area of north Japan in the suger-aging society: YamaCAFe study.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  The 90th Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Expression of podoplanin in synovial tissue of rheumatoid arthritis.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  The 61th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] High-Molecular-Weight adiponectin is correlated with disease activity in the patients with rheumatoid arthritis.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  Orthopaedic Research Society 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] The role of innate sensors in aseptic and septic loosening of total joint arthroplasty.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  Orthopaedic surgery meeting at Stanford University
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Postoperative rehabilitation of atypical femoral fractures in patients with rheumatic diseases.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  The 54th Annual meeting of the Japanese association of rhehabilitation medicine
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Trend of atypical femoral fractures in rheumatic patients in the highly super aging area of North Japan.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  The 61th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Is increasing the trend of primary total hip arthroplasties for the patients with osteoarthritis, but decreasing the rate of female in super-aging area of Japan in last twelve years?2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  EULAR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] The role of innate sensors in aseptic and septic loosening of total joint arthroplasty.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  Ground raound of Orthopaedic surery at Utah University
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Trend of orthopaedic surgeries for the patients with rheumatoid arthritis who are received biologic agents in our institute.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  The 90th Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] The role of innate sensors in aseptic and septic loosening of total joint arthroplasty.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  Orthopaedic surgery meeting at UCSF
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Trend of total hip arthroplasties in the super-aging area in Northern Japan.2017
- Author(s)
  Takakubo Y, et al.
- Organizer
  ISTA 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Is increasing the trend of primary total hip arthroplasties for the patients with osteoarthritis, but decreasing the rate of female in super-aging area of Japan in last twelve years?2017
- Author(s)
  Takakubo Y, Sasaki K, Oki H, Naganuma Y, Narita A, Hirayama T, Tamaki Y, Takagi Y
- Organizer
  EULAR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] The effect of anti-TNF inhibitors on innate immune system in synovial tissues in rheumatoid arthritis patients2016
- Author(s)
  Takakubo Y, Oki H, Yang S, Hanaka N, Sasaki A, Ito J, L Xing, Sasaki K, Takagi M
- Organizer
  2016 International Comibned Meeting of Orthopaedic Research Societies
- Place of Presentation
  Convention center (Xi’an, Chaina)
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] The relationship between reduction pattern and sliding distance in AO/OTA 31-A2/A3 trochanteric fractures in the elderly2016
- Author(s)
  Ito J, Sasaki K, Takakubo Y, Momma R, Takagi M
- Organizer
  The 9th Clare Valley Bone Meeting, Clare Valley
- Place of Presentation
  Clare Convention Centre　（Clare Valley, Australia）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Outcome of rotational acetabular osteotomy for dysplastic follow up for minimum 15 years2016
- Author(s)
  Sasaki K, Ida H, Ishii M, Kawaji H, Takakubo Y, Ito J, Monma R, Takagi M
- Organizer
  The 9th Clare Valley Bone Meeting, Clare Valley
- Place of Presentation
  Clare Convention Centre　（Clare Valley, Australia）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Trend of atypical femoral fractures in rheumatic patients in the highly super aging area of North Japan2016
- Author(s)
  Takakubo Y, Ota D, Naganuma Y, Oki H, Narita A, Ito J, Sasaki K, Takagi M
- Organizer
  European League Against Rheumatism 2016
- Place of Presentation
  Excell center (London, UK)
- Year and Date
  2016-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Expression of Toll-like receptors and distribution of immune-cells in rheumatoid synovial tissues of the patients treated by Abatacept2016
- Author(s)
  Takakubo Y, Naganuma Y, Oki H, Yang S, Sasaki K, Takagi M
- Organizer
  European League Against Rheumatism 2016
- Place of Presentation
  Excell center (London, UK)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 過去11年間の人工股関節手術件数の推移-当院と関連病院の傾向と特徴-2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Organizer
  第42回日本股関節学会学術集会
- Place of Presentation
  グランフロント大阪, 大阪市, 大阪
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 当科における人工股関節感染予防の取り組みと感染率の変化2015
- Author(s)
  佐々木幹, 高窪祐弥, 高木理彰ほか
- Organizer
  第88回日本整形外科学会学術総会
- Place of Presentation
  神戸ポートピアホテル, 神戸市, 兵庫
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 過去11年間の人工股関節手術件数の推移 -当院と関連病院の傾向と特徴-2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Organizer
  第42回日本股関節学会学術集会
- Place of Presentation
  グランフロント大阪, 大阪市, 大阪
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Danage-associated molecular patterns(damps) of toll-like receptors in aseptic loosened total hip arthroplasty.2015
- Author(s)
  Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  ORS annual meeting
- Place of Presentation
  MGM Grand Hotel, Las Vegas, NV, USA
- Year and Date
  2015-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Immunohistochemical localization and cellular reaction of Tlr2 and Nlrp3 cascades in aseptic loosening of totally hip joints.2015
- Author(s)
  Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  ORS annual meeting
- Place of Presentation
  MGM Grand Hotel, Las Vegas, NV, USA
- Year and Date
  2015-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 無菌性弛緩人工股関節の病態におけるNLPR3の関与2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場, 富山市, 富山
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 過去10年間の関節リウマチ (RA)患者における手術件数の推移2014
- Author(s)
  高窪祐弥ら
- Organizer
  第44回人工関節学会
- Place of Presentation
  沖縄コンベンションセンター、沖縄
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 人工股関節インプラント感染症におけるToll-like receptor(TLR)を介した宿主生体反応.2014
- Author(s)
  玉木康信, 佐々木幹, 高窪祐弥, 平山朋幸, 長沼靖, 川路博之, 石井政次, 高木理彰
- Organizer
  第37回日本骨・関節感染症学会.
- Place of Presentation
  京王プラザホテル, 東京
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 過去10年間の高齢者不安定型骨盤輪損傷症例の検討2013
- Author(s)
  高窪祐弥ら
- Organizer
  第40回日本股関節学会学術集会
- Place of Presentation
  広島国際会議場, 広島
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 過去10年間の関節リウマチ (RA)患者における手術件数の推移2013
- Author(s)
  高窪祐弥ら
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  京都国際会議場, 京都
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] RAK2 maintained increased cellular reactivity of macrophages after phagocytosis lipoteichoic acid –coated titanium particles2013
- Author(s)
  Naganuma Y, Hirayama T, Tamaki Y, Takakubo Y, Sasaki K, Takagi M
- Organizer
  59th Orthopaedic Reserch Society
- Place of Presentation
  Henry B Gozalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Role of innate immune sensors in rheumatoid arthritis and osteoarthritis.2013
- Author(s)
  Takakubo Y, Tamaki Y, Barreto G, Konttinen YT, Takagi M
- Organizer
  8th Combined Meeting of Orthopaedic Research Societies
- Place of Presentation
  San Servolo, Venice, Italy
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 山形地区関節リウマチ病診連携ネットワークYARANNA (やらんな) ねっと設立にむけて2013
- Author(s)
  高窪祐弥ら
- Organizer
  第17回山形リウマチセミナー
- Place of Presentation
  メトロポリタン山形、山形
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 生物学的製剤使用下でのリウマチ手術の検討2013
- Author(s)
  高窪祐弥ら
- Organizer
  第42回リウマチの外科研究会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 関節リウマチ (RA)患者に対するメソトレキセート (MTX)投与量の経年的変化2013
- Author(s)
  高窪祐弥ら
- Organizer
  第111回東北整形災害外科学会
- Place of Presentation
  山形国際ホテル, 山形
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 生物学的製剤投与中の入院を要する有害事象の検討2013
- Author(s)
  高窪祐弥ら
- Organizer
  第23回北海道東北RA学会
- Place of Presentation
  フォレスト仙台, 仙台
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Irak2 maintained increased cellular reactivity of macrophages after phagocytosis lipoteichoic acid- coated titanium particles.2013
- Author(s)
  Naganuma Y, Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  59th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Henry B. Gonzalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 関節リウマチ(RA)患者の生物学的製剤投与前血清サイトカイン濃度と治療効果の検討2013
- Author(s)
  高窪祐弥ら
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ, 千葉
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Periprosthetic osteolysis around total hip implantspast, present and future2013
- Author(s)
  Takagi M, Sasaki K, Takakubo Y, Tamaki Y, Hirayama T, Naganuma Y, Kawaji H, Ishii M
- Organizer
  The 57th Annual Fall Congress,Korean Orthopaedic Association
- Place of Presentation
  Grand Hilton Hotel, Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] High mobility group box-1 (HMGB-1) in aseptic and septic loose total hip arthroplasty2013
- Author(s)
  Tamaki Y, Takakubo Y, Hirayama T, Sasaki K, Naganuma Y, Goodman SB, Konttinen YT, Takagi M
- Organizer
  59th Orthopaedic Reserch Society
- Place of Presentation
  Henry B Gozalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Role of innate immune sensors in rheumatoid arthritis and osteoarthritis2013
- Author(s)
  Takakubo Y, et al.
- Organizer
  8th COMBINED MEETING OF ORTHOPAEDIC RESEARCH SOCIETIES
- Place of Presentation
  ヴェニス国際会議場, Venice, Italy
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Expression of toll-like receptors (TLRs) and cathepsin K in periptrosthetic aseptic osteolysis of total hip arthloplasty.2013
- Author(s)
  Tamaki Y, Takakubo, Sasaki K, Takagi M, et al
- Organizer
  59th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Henry B. Gonzalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] High Mobility Group Box-1 (HMGB-1) in Aseptic and Septic Loose Total Hip Arthroplasty2013
- Author(s)
  Tamaki Y, Takakubo Y, Sasaki K, Goodman SB, Konttinen YT, Takagi M, et al
- Organizer
  59th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Henry B. Gonzalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Expression of toll-like receptors (TLRs) and cathepsin K in periprosthetic aseptic osteolysis of total hip arthroplasty.2013
- Author(s)
  Tamaki Y, Takakubo Y, Hirayama T, Naganuma Y, Sasaki K, Goodman SB, Konttinen YT, Takagi M
- Organizer
  59th Orthopaedic Reserch Society
- Place of Presentation
  Henry B Gozalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Innate immune sensors enhanced macrophagic reaction after phagocytosis of wear debris in so called “aseptic ” condition2012
- Author(s)
  Naganuma Y, Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  20th European Orthopaedic Research Society
- Place of Presentation
  ACTA Building, VU University, Amsterdam, Nederland
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 生物学的製剤 (BIO)投与関節リウマチ (RA)滑膜表層組織におけるToll-like receptor (TLR) 陽性細胞の検討2012
- Author(s)
  高窪祐弥ら
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル高輪 (品川)
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 抗tumor necrosis factor (TNF)製剤による関節リウマチ滑膜組織におけるアポト－シスへの影響2012
- Author(s)
  高窪祐弥ら
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場 (名古屋市）
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 生物学的製剤（BIO）投与関節リウマチ（RA）滑膜表層組織におけるToll-like receptor（TLR）陽性細胞の検討2012
- Author(s)
  高窪祐弥、玉木康信、梁秀蘭、大木弘治、平山朋幸、長沼靖、佐々木明子、佐々木幹、大類広、高木理彰
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Supression of TLR4 and IRAK-1, 4 in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles2012
- Author(s)
  Takagi M, Takakubo Y, Sasaki K, Konttinen YT, et al
- Organizer
  20th European Orthopaedic Research Society
- Place of Presentation
  ACTA Building, VU University, Amsterdam, Nederland
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Analysis of Toll-like receptor mediating signal pathway in periprosthetic infection2012
- Author(s)
  Tamaki Y, Takakubo Y, Sasaki K, Konttinen YT, Goodman SB, Takagi M, et al
- Organizer
  20th European Orthopaedic Research Society
- Place of Presentation
  ACTA Building, VU University, Amsterdam, Nederland
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 非感染性弛緩人工股関節周囲組織におけるhigh mobility group box-1（HMGB-1）発現に関する検討2012
- Author(s)
  玉木康信、高窪祐弥、平山朋幸、長沼靖、佐々木幹、川路博之、石井政次、高木理彰
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 生物学的製剤投与中の関節リウマチ患者における人工股関節全置換術後の検討2012
- Author(s)
  高窪祐弥、佐々木幹、玉木康信、大木弘治、長沼靖、川路博之、小林真司、石井政次、高木理彰
- Organizer
  第39回日本股関節学会学術集会
- Place of Presentation
  新潟コンベンションセンター, 新潟
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Lipopolysaccharide（LPS）付着チタン粒子刺激骨髄マクロファージにおけるtoll-like receptors（TLRs）とアダプター分子の発現2012
- Author(s)
  平山朋幸、高木理彰、玉木康信、高窪祐弥、長沼靖、佐々木幹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 感染性，非感染性弛緩人工股関節周囲組織におけるToll-like receptor（TLR）シグナル伝達系の解析2012
- Author(s)
  玉木康信、高窪祐弥、平山朋幸、佐々木幹、佐々木明子、梁秀蘭、長沼靖、石井政次、高木理彰
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] グラム陽性球菌由来病原体関連分子パターンによる免疫応答修飾2012
- Author(s)
  長沼靖、平山朋幸、玉木康信、高窪祐弥、佐々木幹、高木理彰
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] リポテイコ酸付着チタン摩耗粉貪食によるマクロファージ反応性の亢進2012
- Author(s)
  長沼靖、平山朋幸、玉木康信、高窪祐弥、佐々木幹、高木理彰
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] THE CONCENTRATION OF SERUM INTERLEUKIN-6 BEFORE BIOLOGIC TREATMENT ARE RELATED TO CLINICAL RESPONSE IN THE PATIENTS OF RHEUMATOID ARTHRITIS
- Author(s)
  Yuya Takakubo, Hiroharu Ohki, Suran Yang, Akiko Sasaki, Kan Sasaki, Tomoyuki Hirayama, Yasunobu Tamaki, Yasushi Naganuma, Hiroshi Orui, Michiaki Takagi
- Organizer
  European League Against Rheumatism 2014
- Place of Presentation
  Le Palais des Congres de Paris, Paris in France
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] IS PODOPLANIN A NEW CANDIDATE OF INFLAMMATORY MARKERS FOR RHEUMATOID ARTHRITIS?
- Author(s)
  Yuya Takakubo, Hiroharu Ohki, Suran Yang, Akiko Sasaki, Kan Sasaki, Tomoyuki Hirayama, Yasunobu Tamaki, Yasushi Naganuma, Yukinari Kato, Michiaki Takagi
- Organizer
  European League Against Rheumatism 2014
- Place of Presentation
  Le Palais des Congres de Paris, Paris in France
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 山形地区における循環型RA病診連携ネットワーク“やらんなネット”の試み. －二人主治医制の導入を目指して－
- Author(s)
  高窪祐弥, 長沼靖, 大木弘治, 梁秀蘭, 佐々木明子, 大類広, 佐々木幹,高木理彰
- Organizer
  第23回北海道東北RA学会
- Place of Presentation
  北海道大学記念講堂，札幌
- Year and Date
  2014-11-22 – 2014-11-23
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] The concentration of serum interleukin-6 before biologic treatment are related to clinical response in the patients of rheumatoid arthritis.
- Author(s)
  Takakubo Y, Ohki H, Yang S, Sasaki A, Sasaki K, Hirayama T,Tamaki Y,Naganuma Y,Orui H, Takagi M
- Organizer
  European League Against Rheumatism 2014
- Place of Presentation
  Palais des Congres, Paris, France
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] リポテイコ酸付着チタン摩耗粉貪食マクロファージの免疫応答修飾におけるTLR2及びNLRP3反応系の関与
- Author(s)
  長沼靖、平山朋幸、大木弘治、梁秀蘭、丸山真博、玉木康信、高窪祐弥、佐々木幹、高木理彰
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル, 鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Decreasing trend of total joint arthroplasties for rheumatoid patients compared to osteoarthritis patients in our institutes in last decade
- Author(s)
  Yuya Takakubo, Kan Sasaki, Hiroharu Oki, Yasushi Naganuma, Atsushi Narita, Tomoyuki Hirayama, Yasunobu Tamaki, Michiaki Takagi
- Organizer
  European League Against Rheumatism 2015
- Place of Presentation
  Fiera Roma, Roma, Italy
- Year and Date
  2015-06-09 – 2015-06-13
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] RA滑膜組織における生物学的製剤の自然免疫系への影響
- Author(s)
  高窪祐弥, 玉木康信, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 佐々木幹, 大類広, 高木理彰
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル，東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 山形地区における循環型RA病診連携ネットワーク“やらんなネット”の試み
- Author(s)
  高窪祐弥, 佐々木幹, 玉木康信, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 高木理彰
- Organizer
  第42回日本関節病学会学術集会
- Place of Presentation
  虎ノ門ヒルズ，東京
- Year and Date
  2014-11-06 – 2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 異物肉芽腫反応とリウマチ性関節炎におけるマクロファージの役割.
- Author(s)
  玉木康信, Jukka Pajarinen, 高窪祐弥, 梁秀蘭, 長沼靖, 平山朋幸, 大木弘治, 佐々木幹, 川路博之, 石井政次, Hekki Valleala, Yrjo T. Konttinen, Stuart B. Goodman, 高木理彰
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル, 鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Analyses on immunohistochemical localization of TLR2 and NLRP3 in aseptic periprosthetic tissues around loose hip joints and their response to foreign body particles.
- Author(s)
  Naganuma Y, Hirayama T, Tamaki Y, Takakubo Y, Oki H, Yang S, Sasaki K, Kawaji H, Ishii M, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] リポテイコ酸刺激マクロファージにおけるTLR2およびTLR6の発現様式
- Author(s)
  長沼靖、大木弘治、梁秀蘭、平山朋幸、玉木康信、高窪祐弥、結城北斗、佐々木明子、佐々木幹、高木理彰
- Organizer
  第58回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 山形地区における関節リウマチ病診連携ネットワーク (やらんなねっと) の現状と問題点
- Author(s)
  高窪祐弥, 玉木康信, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 佐々木幹, 大類広, 高木理彰
- Organizer
  第57回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル，東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 超高齢社会にむけたリウマチ治療の未来‐東日本（山形県）の取り組み－
- Author(s)
  高窪祐弥, 佐々木幹,玉木康信, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 大類広, 高木理彰
- Organizer
  第87回日本整形外科学会
- Place of Presentation
  神戸国際会議場, 神戸
- Year and Date
  2014-05-21 – 2014-05-25
- Invited
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Total Joint Arthroplasties for Rheumatoid Arthritis in Era of Biologics.
- Author(s)
  Takakubo Y, Sasaki K, Narita A, Oki H, Hirayama T, Suzuki A, TamakiY, Togashi E, Kawaji H, Fukushima S, Ishii M, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 高齢者不安定型骨盤輪損傷症例の治療経過の検討
- Author(s)
  高窪祐弥, 佐々木幹, 成田淳,　長谷川浩士,　成田亜矢,　金内ゆみ子,　小林真司,　高木理彰
- Organizer
  第51回日本リハビリテーション医学会学術集会
- Place of Presentation
  名古屋国際会議場，名古屋
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] リウマチ性疾患における微小粒子と形質細胞様樹状細胞の検討
- Author(s)
  高窪祐弥, 佐々木幹, 玉木康信, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 高木理彰
- Organizer
  第42回日本関節病学会学術集会
- Place of Presentation
  虎ノ門ヒルズ，東京
- Year and Date
  2014-11-06 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 過去10年間の人工関節手術件数の推移-当院と関連病院の傾向と特徴-
- Author(s)
  高窪祐弥、佐々木幹、玉木康信、大木弘治、長沼靖、平山朋幸、成田淳、浅野多聞、冨樫栄太、福島重宣、　川路博之、石井政次、　高木理彰
- Organizer
  第45回日本人工関節外科学会
- Place of Presentation
  福岡国際会議場，福岡
- Year and Date
  2015-02-27 – 2015-02-28
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] The outcome of treatment for infected total hip.
- Author(s)
  Sasaki K, Ishii M, Kawaji H, Takakubo Y, Tamakai Y, Hirayama T, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 生物学的製剤時代の関節リウマチ患者における人工股関節手術件数の推移
- Author(s)
  高窪祐弥, 佐々木幹, 玉木康信, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 高木理彰
- Organizer
  第41回日本股関節学会学術集会
- Place of Presentation
  京王プラザホテル，東京
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Is podoplanin a new candidate of inflammatory markers for rheumatoid arthritis?
- Author(s)
  Takakubo Y, Ohki H, Yang S, Sasaki A, Sasaki K, Hirayama T,Tamaki Y,Naganuma Y, Yukinari Kato, Takagi M
- Organizer
  European League Against Rheumatism 2014
- Place of Presentation
  Palais des Congres, Paris, France
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] リウマチ性疾患における微小粒子による形質細胞様樹状細胞の刺激
- Author(s)
  高窪祐弥, 高木理彰, Yrjo T Konttinen
- Organizer
  第12回山形リウマチセミナー
- Place of Presentation
  メトロポリタン山形 (山形市）
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Are atypical femoral fractures in rheumatic patients increasing?
- Author(s)
  Yuya Takakubo, Syouta Okuda, Yasushi Naganuma, Ryuta Ooishi, Hiroharu Oki, Yasuhobu Tamaki, Akiko Sasaki, Atsushi Narita, Tomoyuki Hirayama, Kan Sasaki, Michiaki Takagi
- Organizer
  European League Against Rheumatism 2015
- Place of Presentation
  Fiera Roma, Roma, Italy
- Year and Date
  2015-06-09 – 2015-06-13
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Total Joint Arthroplasties for Rheumatoid Arthritis in Era of Biologics
- Author(s)
  Yuya Takakubo, Kan Sasaki, Hiroharu Oki, Yasushi Naganuma, Atsushi Narita, Tomoyuki Hirayama, Yasunobu Tamaki, Michiaki Takagi
- Organizer
  ISTA
- Place of Presentation
  京都国際会議場, Kyoto in Japan
- Year and Date
  2014-09-24 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 関節リウマチ(RA)滑膜組織におけるポドプラニン陽性細胞の検討
- Author(s)
  高窪祐弥, 佐々木幹, 玉木康信, 梁秀蘭, 大木弘治, 平山朋幸, 佐々木明子, 長沼靖, 高木理彰
- Organizer
  第29回日本整形基礎学術集会
- Place of Presentation
  城山観光ホテル，鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] 弛緩人工股関節異物肉芽腫組織におけるTLR2、NLRP-3シグナル伝達機構に関する免疫組織化学的検討
- Author(s)
  長沼靖、高窪祐弥、佐々木幹、佐々木明子、玉木康信、成田淳、梁秀蘭、大木弘治、結城北斗、高木理彰
- Organizer
  第58回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Immunohistochemical localization and cellular reaction of TLR2 and NLRP3 cascades in aseptic loosening of totally replaced hip joints.
- Author(s)
  Naganuma Y, Hirayama T, Ooki H, Liu X, Yang S, Tamaki Y, Takakubo Y, Sasaki K, Takagi M
- Organizer
  Orthopaedic Research Society annual meeting
- Place of Presentation
  MGM Grand Hotel, Las Vegas, Nevada USA
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 高窪祐弥, 大木弘治, 佐々木幹, 玉木康信, 梁秀蘭, 成田淳, 佐々木明子, 長沼靖, 高木理彰
- Author(s)
  高窪祐弥, 大木弘治, 佐々木幹, 玉木康信, 梁秀蘭, 成田淳, 佐々木明子, 長沼靖, 高木理彰
- Organizer
  第29回日本整形基礎学術集会
- Place of Presentation
  城山観光ホテル，鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24791522
[Presentation] Mid-term clinical results of PINNACLE metal on metal total hip arthroplasty
- Author(s)
  Hirayama T, Sasaki K, Takakubo Y, Ito J, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] RA前足部変形に対するMann変法とoff-set osteotomyによる中足骨頭温存手術の中長期成績
- Author(s)
  高窪祐弥, 長沼靖, 大木弘治, 高木理彰
- Organizer
  第43回リウマチの外科研究会
- Place of Presentation
  グランフロント大阪，大阪
- Year and Date
  2014-08-30 – 2014-08-31
- Invited
- Data Source
  KAKENHI-PROJECT-24791522

1. TAKAGI Michiaki (40241707)

# of Collaborated Projects: 6 results

# of Collaborated Products: 107 results
2. SASAKI Kan (00444034)

# of Collaborated Projects: 4 results

# of Collaborated Products: 74 results
3. 長沼靖 (10463811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. 大木弘治 (20463812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 伊藤重治 (50764122)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. TAKAKUBO Yuya (80431461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. tsuchiya takashi (30400576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUGAWARA Masato (60444030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 丸山真博 (00740870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 本間龍介 (70716688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 鈴木智人 (90599416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大江倫太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAKUBO Yuya 高窪 祐弥

高窪 祐弥 タカクボ ユウヤ

Research Projects

Research Products

Co-Researchers

人工関節周囲感染の制御に向けたマクロファージによる細胞治療の基礎研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Innate immune receptor and alternative autophagy in pathogenesis of prosthetic joint infection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of innate immunology in the patients with early rheumatoid arthritis and resistant-anti rheumatic drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Innate immunity reaction in marcophage for periprosthetic joint infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between expression of isocitrate dehydrogenase and clinical outcomes in patients with osteosarcoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of innate immune sensors, TLR and NLR, in periprosthetic infection.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Does microparticles induce innate immunity with stimulation plasmacytoid dendritic cells in rheumatic diseases?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 変形性関節症（股関節）の手術療法 ～骨切り術から人工股関節置換術まで～2017

Author(s)

Total Pages

Publisher

Data Source

[Book] 変形性関節症（股関節）の手術療法 ～骨切り術から人工股関節置換術まで～2017

Author(s)

Total Pages

Publisher

Data Source

[Book] Bio-tribocorrosion in biomaterials and medical implants2013

Author(s)

Total Pages

Publisher

Data Source

[Book] Book of Bio-tribocorrosion in biomaterials and medical implants, Wear-corrosion mechanisms. In: 9. LOOSENING OF TOTAL JOINT REPLACEMENT,2013

Author(s)

Total Pages

Publisher

Data Source

[Book] Recent Advances in Arthroplasty: What we know about the physiological reactions of the local tissue on the prosthesis and its wear products2012

Author(s)

Total Pages

Publisher

Data Source

[Book] Wear of orthopaedic implants and artificial joints: Materials used for hip and knee implants. Saverio A (Ed.), In: Wear of orthopaedic implants and artificial joints.2012

Author(s)

Publisher

Data Source

[Book] Infected Total Joint Arthroplasty: Biomaterial-host interactions in aseptic and septic conditions, In: Infected total joint arthroplasty. The algorithmic approach2012

Author(s)

Publisher

Data Source

TAKAKUBO Yuya 高窪祐弥

高窪祐弥タカクボユウヤ

[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017

[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017

[Journal Article] Activation of plasmacytoid dendritic cells by apoptotic particles - mechanism for the loss of immunological tolerance in Sjögren's syndrome.2018