Omatsu Yoshiki 尾松芳樹

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OMATSU Yoshiki 尾松芳樹

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Researcher Number	80437277
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院生命機能研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院生命機能研究科, 准教授 2020 – 2021: 大阪大学, 生命機能研究科, 准教授 2016 – 2019: 大阪大学, 医学系研究科, 助教 2012: 京都大学, 再生医科学研究所, 助教 2011: 京都大学, 再生医科学研究所, 研究員
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49030:Experimental pathology-related / Basic Section 44020:Developmental biology-related Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator 骨髄 / 造血幹細胞 / ニッチ / Foxc1 / CAR細胞 / 間葉系幹細胞 / 造血幹細胞ニッチ / 線維化 / 慢性骨髄性白血病 / 発生 … More / 転写因子 / 間葉系細胞 / Ebf3 / ケモカイン / サイトカイン … More Except Principal Investigator single-cell RNA-seq / 骨髄間質ネットワーク / 肺間質ネットワーク / 間質細胞 / 骨髄病態生理 / 肺病態生理 / 複雑系間質ネットワーク / 臓器連関 / 複雑系細胞クロストーク / 血管リンパ管系 / 大腸炎 / 肺線維症 / 間質と実質 / 間質リテラシー / 血管・リンパ管系 / 間葉系 / 神経系 / 免疫系 / 間質 Less

Establishment of interstitial literacy based on complex systems crosstalk
- Principal Investigator
  
  佐藤荘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Medical and Dental University
Investigation of the roles of stromal cell interactions in lung-bone marrow crosstalk
- Principal Investigator
  
  七野成之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo University of Science
Molecular mechanisms of the alteration of the bone marrow hematopoietic niche in leukemia and other diseases.Principal Investigator
- Principal Investigator
  
  尾松芳樹
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Osaka University
Gene regulatory network in cellular niches for hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Omatsu Yoshiki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osaka University
Dynamism and functions of niches for hematopoietic stem/progenitor cells in bone marrowPrincipal Investigator
- Principal Investigator
  
  OMATSU Yoshiki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Molecular basis of hematopoietic stem and progenitor niche formationPrincipal Investigator
- Principal Investigator
  
  OMATSU Yoshiki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2012 2011

All Journal Article Presentation

[Journal Article] Acute malaria suppresses the B lymphocytic niche in the bone marrow through the alteration of CXCL12-abundant reticular cells2024
- Author(s)
  Lee Michelle Sue Jann、Matsuo Dapaah Julia、Del Rosario Zorrilla Camila、Omatsu Yoshiki、Nagasawa Takashi、Uemura Shun、Iwama Atsushi、Ishii Ken J、Coban Cevayir
- Journal Title
  
  International Immunology
  
  Volume: 36 Issue: 7 Pages: 1-1
- DOI
  10.1093/intimm/dxae012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15448, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
[Journal Article] Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions2023
- Author(s)
  Omatsu Y
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 43 Issue: 1 Pages: 15-15
- DOI
  10.1186/s41232-023-00267-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-23K24112
[Journal Article] Ebf3+ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells2023
- Author(s)
  Nakatani Taichi、Sugiyama Tatsuki、Omatsu Yoshiki、Watanabe Hitomi、Kondoh Gen、Nagasawa Takashi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 6402-6402
- DOI
  10.1038/s41467-023-42047-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H05627, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
[Journal Article] ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts2022
- Author(s)
  Yan Minglu、Komatsu Noriko、Muro Ryunosuke、Huynh Nam Cong-Nhat、Kitazawa Riko、Kitazawa Sohei、Pluemsakunthai Warunee、Mitsui Yuichi、Satoh Takashi、Okamura Tadashi、Nitta Takeshi、Im Sin-Hyeog、Kim Chan Johng、Kollias George、Tanaka Sakae、Okamoto Kazuo、Tsukasaki Masayuki、Takayanagi Hiroshi
- Journal Title
  
  Nature Immunology
  
  Volume: 23 Issue: 9 Pages: 1330-1341
- DOI
  10.1038/s41590-022-01285-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06981, KAKENHI-PROJECT-22K07114, KAKENHI-PROJECT-21K18254, KAKENHI-PROJECT-21K19354, KAKENHI-ORGANIZER-22H05060, KAKENHI-PLANNED-22H05061, KAKENHI-PROJECT-21H05046, KAKENHI-PROJECT-20H03465, KAKENHI-PROJECT-21H03104, KAKENHI-PROJECT-22F22108, KAKENHI-PROJECT-21K19371, KAKENHI-PROJECT-23K20314, KAKENHI-PROJECT-23K24106, KAKENHI-PROJECT-23K24148, KAKENHI-PROJECT-23K24454
[Journal Article] Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells2022
- Author(s)
  Omatsu Yoshiki、Aiba Shota、Maeta Tomonori、Higaki Kei、Aoki Kazunari、Watanabe Hitomi、Kondoh Gen、Nishimura Riko、Takeda Shu、Chung Ung-il、Nagasawa Takashi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 2654-2654
- DOI
  10.1038/s41467-022-30266-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08393, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
[Journal Article] A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis2021
- Author(s)
  Nakagawa Toshinori、Jorg David J.、Watanabe Hitomi、Mizuno Seiya、Han Seungmin、Ikeda Tatsuro、Omatsu Yoshiki、Nishimura Keiko、Fujita Miyako、Takahashi Satoru、Kondoh Gen、Simons Benjamin D.、Yoshida Shosei、Nagasawa Takashi
- Journal Title
  
  Cell Reports
  
  Volume: 37 Issue: 3 Pages: 109875-109875
- DOI
  10.1016/j.celrep.2021.109875
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06688, KAKENHI-PROJECT-18H03998, KAKENHI-PROJECT-19J00410, KAKENHI-PLANNED-18H05551
[Journal Article] Identification of microenvironmental niches for hematopoietic stem cells and lymphoid progenitors - bone marrow fibroblastic reticular cells with salient features2021
- Author(s)
  Omatsu Yoshiki、Nagasawa Takashi
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 821-826
- DOI
  10.1093/intimm/dxab092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06688, KAKENHI-PROJECT-18H03998
[Journal Article] Cellular Niches for Hematopoietic Stem Cells and Lympho-Hematopoiesis in Bone Marrow During Homeostasis and Blood Cancers2021
- Author(s)
  Omatsu Yoshiki、Higaki Kei、Nagasawa Takashi
- Journal Title
  
  Curr Top Microbiol Immunol.
  
  Volume: 434 Pages: 33-54
- DOI
  10.1007/978-3-030-86016-5_2
- ISBN
  9783030860158, 9783030860165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06688
[Journal Article] Niches for hematopoietic stem cells and immune cell progenitors.2019
- Author(s)
  Sugiyama, T., Omatsu, Y., and Nagasawa, T.
- Journal Title
  
  Int Immunol.
  
  Volume: 31 Issue: 1 Pages: 5-11
- DOI
  10.1093/intimm/dxy058
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05643, KAKENHI-PROJECT-18H03998, KAKENHI-PROJECT-16H06232
[Journal Article] Stem cell nich-specific Ebf3 maintains the bone marrow cavity.2018
- Author(s)
  Seike, M., Omatsu, Y., Watanabe, H., Kondoh, G., Nagasawa, T.
- Journal Title
  
  Genes ＆ Development
  
  Volume: 32 Issue: 5-6 Pages: 359-372
- DOI
  10.1101/gad.311068.117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05643, KAKENHI-PROJECT-16H06232, KAKENHI-PROJECT-15K21098
[Journal Article] 造血幹細胞を維持する骨髄微小環境2016
- Author(s)
  尾松芳樹
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 26(5) Pages: 19-24
- Data Source
  KAKENHI-PROJECT-16H06232
[Journal Article] CAR細胞による造血幹細胞・前駆細胞の制御2016
- Author(s)
  尾松芳樹
- Journal Title
  
  実験医学増刊
  
  Volume: 34(17) Pages: 34-39
- Data Source
  KAKENHI-PROJECT-16H06232
[Journal Article] Extracellul- ar matrix protein Tenascin-C is req- uired in the bone marrow microenvio- nment primed for hematopoietic rege- neration2012
- Author(s)
  Nakamura-Ishizu A, Okuno Y, Omatsu Y, Okabe K, Morimoto J, Uede T, Nagasa- wa T, Suda T, Kubota Y
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 23 Pages: 5429-5437
- DOI
  10.1182/blood-2011-11-393645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-21689047, KAKENHI-PROJECT-22390096, KAKENHI-PUBLICLY-23111536, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23790533, KAKENHI-PROJECT-24790983, KAKENHI-PLANNED-22122002, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003
[Journal Article] Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero.2011
- Author(s)
  Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, Nakamura-Ishizu A, Sano K, Murakami M, Ema M, Omatsu Y, Takahashi S, Nagasawa T, Shibuya M, Okano H, Suda T.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 208(5) Pages: 949-960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790533
[Journal Article] Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero2011
- Author(s)
  Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Sano K, Murakami M, Ema M, Omatsu Y, Takahashi S, Nagasawa T, Shibuya M, Okano H, Suda T
- Journal Title
  
  J Exp Med
  
  Volume: 208 Issue: 5 Pages: 949-960
- DOI
  10.1084/jem.20102187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220009, KAKENHI-PUBLICLY-22021019, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-22390096, KAKENHI-PUBLICLY-23111536, KAKENHI-PUBLICLY-23118527, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-23790533
[Journal Article] Control of hematopoietic stem cells by the bone marrow stromal niche : the role of reticular cells2011
- Author(s)
  Nagasawa, T., Omatsu, Y., Sugiyama, T.
- Journal Title
  
  Trends Immunol.
  
  Volume: 32 Issue: 7 Pages: 315-320
- DOI
  10.1016/j.it.2011.03.009
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021019, KAKENHI-PROJECT-22390096, KAKENHI-PROJECT-22790910, KAKENHI-PUBLICLY-23111536, KAKENHI-PUBLICLY-23118514, KAKENHI-PROJECT-23790533
[Presentation] 定常状態および疾患における造血幹細胞ニッチ2023
- Author(s)
  尾松芳樹
- Organizer
  第22回日本再生医療学会シンポジウム, 2023年3月25日, 京都
- Invited
- Data Source
  KAKENHI-PROJECT-23K24112
[Presentation] 定常状態および疾患における造血幹細胞ニッチ2023
- Author(s)
  尾松芳樹
- Organizer
  230325 第22回日本再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24112
[Presentation] 定常状態および疾患における造血幹細胞ニッチ2023
- Author(s)
  尾松芳樹
- Organizer
  第22回日本再生医療学会総会, シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-22H05064
[Presentation] Cellular niches for hematopoietic stem and progenitor cells in the adult bone marrow.2022
- Author(s)
  尾松芳樹
- Organizer
  第51回日本免疫学会シンポジウム, 2022年12月7日, 熊本
- Invited
- Data Source
  KAKENHI-PROJECT-23K24112
[Presentation] 骨髄造血幹細胞ニッチを構成する間葉系幹細胞2021
- Author(s)
  尾松芳樹
- Organizer
  第42回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06688
[Presentation] Niches for hematopoietic stem cells in bone marrow2021
- Author(s)
  尾松芳樹
- Organizer
  Virtual Immunology2021 (American Association of Immunologists)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06688
[Presentation] 造血幹・前駆細胞ニッチを構成するCAR細胞は骨芽細胞と骨髄脂肪細胞を供給する間葉系幹細胞である2020
- Author(s)
  尾松芳樹
- Organizer
  第38回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06688
[Presentation] 骨髄：造血の恒常性を担う微小環境の形成と維持の分子基盤2017
- Author(s)
  尾松芳樹
- Organizer
  第122回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎大学（長崎県長崎市）
- Invited
- Data Source
  KAKENHI-PROJECT-16H06232
[Presentation] 造血幹細胞・前駆細胞を維持する骨髄のニッチ2016
- Author(s)
  尾松芳樹
- Organizer
  第37回炎症・再生医学会
- Place of Presentation
  京都市勧業館（京都府京都市）
- Invited
- Data Source
  KAKENHI-PROJECT-16H06232
[Presentation] 造血幹細胞・前駆細胞を維持するニッチの研究2016
- Author(s)
  尾松芳樹
- Organizer
  血小板・巨核球学術講演会
- Place of Presentation
  ホテルニューオータニ大阪（大阪府大阪市）
- Invited
- Data Source
  KAKENHI-PROJECT-16H06232

1. 七野成之 (70822435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 佐藤荘 (60619716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 内藤尚道 (30570676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 石亀晴道 (70729227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 伊藤美菜子 (70793115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 増田隆博 (80615287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田井育江 (90749508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MORIMOTO Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. LEE MICHELLE

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 長澤丘司

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 上出利光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 依馬正次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 北澤理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 青木一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Omatsu Yoshiki 尾松 芳樹

OMATSU Yoshiki 尾松 芳樹

Research Projects

Research Products

Co-Researchers

Establishment of interstitial literacy based on complex systems crosstalk

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the roles of stromal cell interactions in lung-bone marrow crosstalk

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of the alteration of the bone marrow hematopoietic niche in leukemia and other diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Gene regulatory network in cellular niches for hematopoietic stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dynamism and functions of niches for hematopoietic stem/progenitor cells in bone marrowPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis of hematopoietic stem and progenitor niche formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acute malaria suppresses the B lymphocytic niche in the bone marrow through the alteration of CXCL12-abundant reticular cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ebf3+ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of microenvironmental niches for hematopoietic stem cells and lymphoid progenitors - bone marrow fibroblastic reticular cells with salient features2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular Niches for Hematopoietic Stem Cells and Lympho-Hematopoiesis in Bone Marrow During Homeostasis and Blood Cancers2021

Author(s)

Journal Title

DOI

Omatsu Yoshiki 尾松芳樹

OMATSU Yoshiki 尾松芳樹