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Omatsu Yoshiki  尾松 芳樹

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OMATSU Yoshiki  尾松 芳樹

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Researcher Number 80437277
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院生命機能研究科, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪大学, 大学院生命機能研究科, 准教授
2020 – 2021: 大阪大学, 生命機能研究科, 准教授
2016 – 2019: 大阪大学, 医学系研究科, 助教
2012: 京都大学, 再生医科学研究所, 助教
2011: 京都大学, 再生医科学研究所, 研究員
Review Section/Research Field
Principal Investigator
Immunology / Basic Section 49030:Experimental pathology-related / Basic Section 44020:Developmental biology-related
Except Principal Investigator
Transformative Research Areas, Section (III)
Keywords
Principal Investigator
骨髄 / 造血幹細胞 / ニッチ / Foxc1 / CAR細胞 / 間葉系幹細胞 / 造血幹細胞ニッチ / 線維化 / 慢性骨髄性白血病 / 発生 … More / 転写因子 / 間葉系細胞 / Ebf3 / ケモカイン / サイトカイン … More
Except Principal Investigator
single-cell RNA-seq / 骨髄間質ネットワーク / 肺間質ネットワーク / 間質細胞 / 骨髄病態生理 / 肺病態生理 / 複雑系間質ネットワーク / 臓器連関 / 複雑系細胞クロストーク / 血管リンパ管系 / 大腸炎 / 肺線維症 / 間質と実質 / 間質リテラシー / 血管・リンパ管系 / 間葉系 / 神経系 / 免疫系 / 間質 Less
  • Research Projects

    (6 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (15 People)
  •  Establishment of interstitial literacy based on complex systems crosstalk

    • Principal Investigator
      佐藤 荘
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tokyo Medical and Dental University
  •  Investigation of the roles of stromal cell interactions in lung-bone marrow crosstalk

    • Principal Investigator
      七野 成之
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tokyo University of Science
  •  Molecular mechanisms of the alteration of the bone marrow hematopoietic niche in leukemia and other diseases.Principal Investigator

    • Principal Investigator
      尾松 芳樹
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Osaka University
  •  Gene regulatory network in cellular niches for hematopoietic stem cellsPrincipal Investigator

    • Principal Investigator
      Omatsu Yoshiki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Osaka University
  •  Dynamism and functions of niches for hematopoietic stem/progenitor cells in bone marrowPrincipal Investigator

    • Principal Investigator
      OMATSU Yoshiki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Molecular basis of hematopoietic stem and progenitor niche formationPrincipal Investigator

    • Principal Investigator
      OMATSU Yoshiki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2012 2011

All Journal Article Presentation

  • [Journal Article] Acute malaria suppresses the B lymphocytic niche in the bone marrow through the alteration of CXCL12-abundant reticular cells2024

    • Author(s)
      Lee Michelle Sue Jann、Matsuo Dapaah Julia、Del Rosario Zorrilla Camila、Omatsu Yoshiki、Nagasawa Takashi、Uemura Shun、Iwama Atsushi、Ishii Ken J、Coban Cevayir
    • Journal Title

      International Immunology

      Volume: 36 Issue: 7 Pages: 1-1

    • DOI

      10.1093/intimm/dxae012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15448, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
  • [Journal Article] Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions2023

    • Author(s)
      Omatsu Y
    • Journal Title

      Inflammation and Regeneration

      Volume: 43 Issue: 1 Pages: 15-15

    • DOI

      10.1186/s41232-023-00267-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-23K24112
  • [Journal Article] Ebf3+ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells2023

    • Author(s)
      Nakatani Taichi、Sugiyama Tatsuki、Omatsu Yoshiki、Watanabe Hitomi、Kondoh Gen、Nagasawa Takashi
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 6402-6402

    • DOI

      10.1038/s41467-023-42047-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-22H05627, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
  • [Journal Article] ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts2022

    • Author(s)
      Yan Minglu、Komatsu Noriko、Muro Ryunosuke、Huynh Nam Cong-Nhat、Kitazawa Riko、Kitazawa Sohei、Pluemsakunthai Warunee、Mitsui Yuichi、Satoh Takashi、Okamura Tadashi、Nitta Takeshi、Im Sin-Hyeog、Kim Chan Johng、Kollias George、Tanaka Sakae、Okamoto Kazuo、Tsukasaki Masayuki、Takayanagi Hiroshi
    • Journal Title

      Nature Immunology

      Volume: 23 Issue: 9 Pages: 1330-1341

    • DOI

      10.1038/s41590-022-01285-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06981, KAKENHI-PROJECT-22K07114, KAKENHI-PROJECT-21K18254, KAKENHI-PROJECT-21K19354, KAKENHI-ORGANIZER-22H05060, KAKENHI-PLANNED-22H05061, KAKENHI-PROJECT-21H05046, KAKENHI-PROJECT-20H03465, KAKENHI-PROJECT-21H03104, KAKENHI-PROJECT-22F22108, KAKENHI-PROJECT-21K19371, KAKENHI-PROJECT-23K20314, KAKENHI-PROJECT-23K24106, KAKENHI-PROJECT-23K24148, KAKENHI-PROJECT-23K24454
  • [Journal Article] Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells2022

    • Author(s)
      Omatsu Yoshiki、Aiba Shota、Maeta Tomonori、Higaki Kei、Aoki Kazunari、Watanabe Hitomi、Kondoh Gen、Nishimura Riko、Takeda Shu、Chung Ung-il、Nagasawa Takashi
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 2654-2654

    • DOI

      10.1038/s41467-022-30266-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08393, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-21H04959, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-23K24112, KAKENHI-PROJECT-23K24152
  • [Journal Article] A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis2021

    • Author(s)
      Nakagawa Toshinori、Jorg David J.、Watanabe Hitomi、Mizuno Seiya、Han Seungmin、Ikeda Tatsuro、Omatsu Yoshiki、Nishimura Keiko、Fujita Miyako、Takahashi Satoru、Kondoh Gen、Simons Benjamin D.、Yoshida Shosei、Nagasawa Takashi
    • Journal Title

      Cell Reports

      Volume: 37 Issue: 3 Pages: 109875-109875

    • DOI

      10.1016/j.celrep.2021.109875

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06688, KAKENHI-PROJECT-18H03998, KAKENHI-PROJECT-19J00410, KAKENHI-PLANNED-18H05551
  • [Journal Article] Identification of microenvironmental niches for hematopoietic stem cells and lymphoid progenitors - bone marrow fibroblastic reticular cells with salient features2021

    • Author(s)
      Omatsu Yoshiki、Nagasawa Takashi
    • Journal Title

      International Immunology

      Volume: 33 Issue: 12 Pages: 821-826

    • DOI

      10.1093/intimm/dxab092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06688, KAKENHI-PROJECT-18H03998
  • [Journal Article] Cellular Niches for Hematopoietic Stem Cells and Lympho-Hematopoiesis in Bone Marrow During Homeostasis and Blood Cancers2021

    • Author(s)
      Omatsu Yoshiki、Higaki Kei、Nagasawa Takashi
    • Journal Title

      Curr Top Microbiol Immunol.

      Volume: 434 Pages: 33-54

    • DOI

      10.1007/978-3-030-86016-5_2

    • ISBN
      9783030860158, 9783030860165
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06688
  • [Journal Article] Niches for hematopoietic stem cells and immune cell progenitors.2019

    • Author(s)
      Sugiyama, T., Omatsu, Y., and Nagasawa, T.
    • Journal Title

      Int Immunol.

      Volume: 31 Issue: 1 Pages: 5-11

    • DOI

      10.1093/intimm/dxy058

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05643, KAKENHI-PROJECT-18H03998, KAKENHI-PROJECT-16H06232
  • [Journal Article] Stem cell nich-specific Ebf3 maintains the bone marrow cavity.2018

    • Author(s)
      Seike, M., Omatsu, Y., Watanabe, H., Kondoh, G., Nagasawa, T.
    • Journal Title

      Genes & Development

      Volume: 32 Issue: 5-6 Pages: 359-372

    • DOI

      10.1101/gad.311068.117

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05643, KAKENHI-PROJECT-16H06232, KAKENHI-PROJECT-15K21098
  • [Journal Article] 造血幹細胞を維持する骨髄微小環境2016

    • Author(s)
      尾松芳樹
    • Journal Title

      CLINICAL CALCIUM

      Volume: 26(5) Pages: 19-24

    • Data Source
      KAKENHI-PROJECT-16H06232
  • [Journal Article] CAR細胞による造血幹細胞・前駆細胞の制御2016

    • Author(s)
      尾松芳樹
    • Journal Title

      実験医学 増刊

      Volume: 34(17) Pages: 34-39

    • Data Source
      KAKENHI-PROJECT-16H06232
  • [Journal Article] Extracellul- ar matrix protein Tenascin-C is req- uired in the bone marrow microenvio- nment primed for hematopoietic rege- neration2012

    • Author(s)
      Nakamura-Ishizu A, Okuno Y, Omatsu Y, Okabe K, Morimoto J, Uede T, Nagasa- wa T, Suda T, Kubota Y
    • Journal Title

      Blood

      Volume: 119 Issue: 23 Pages: 5429-5437

    • DOI

      10.1182/blood-2011-11-393645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-21689047, KAKENHI-PROJECT-22390096, KAKENHI-PUBLICLY-23111536, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23790533, KAKENHI-PROJECT-24790983, KAKENHI-PLANNED-22122002, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003
  • [Journal Article] Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero.2011

    • Author(s)
      Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, Nakamura-Ishizu A, Sano K, Murakami M, Ema M, Omatsu Y, Takahashi S, Nagasawa T, Shibuya M, Okano H, Suda T.
    • Journal Title

      J. Exp. Med.

      Volume: 208(5) Pages: 949-960

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790533
  • [Journal Article] Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero2011

    • Author(s)
      Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Sano K, Murakami M, Ema M, Omatsu Y, Takahashi S, Nagasawa T, Shibuya M, Okano H, Suda T
    • Journal Title

      J Exp Med

      Volume: 208 Issue: 5 Pages: 949-960

    • DOI

      10.1084/jem.20102187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220009, KAKENHI-PUBLICLY-22021019, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-22390096, KAKENHI-PUBLICLY-23111536, KAKENHI-PUBLICLY-23118527, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-23790533
  • [Journal Article] Control of hematopoietic stem cells by the bone marrow stromal niche : the role of reticular cells2011

    • Author(s)
      Nagasawa, T., Omatsu, Y., Sugiyama, T.
    • Journal Title

      Trends Immunol.

      Volume: 32 Issue: 7 Pages: 315-320

    • DOI

      10.1016/j.it.2011.03.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22021019, KAKENHI-PROJECT-22390096, KAKENHI-PROJECT-22790910, KAKENHI-PUBLICLY-23111536, KAKENHI-PUBLICLY-23118514, KAKENHI-PROJECT-23790533
  • [Presentation] 定常状態および疾患における造血幹細胞ニッチ2023

    • Author(s)
      尾松芳樹
    • Organizer
      第22回 日本再生医療学会 シンポジウム, 2023年3月25日, 京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24112
  • [Presentation] 定常状態および疾患における造血幹細胞ニッチ2023

    • Author(s)
      尾松芳樹
    • Organizer
      230325 第22回日本再生医療学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24112
  • [Presentation] 定常状態および疾患における造血幹細胞ニッチ2023

    • Author(s)
      尾松芳樹
    • Organizer
      第22回 日本再生医療学会総会, シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-22H05064
  • [Presentation] Cellular niches for hematopoietic stem and progenitor cells in the adult bone marrow.2022

    • Author(s)
      尾松芳樹
    • Organizer
      第51回 日本免疫学会 シンポジウム, 2022年12月7日, 熊本
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24112
  • [Presentation] 骨髄造血幹細胞ニッチを構成する間葉系幹細胞2021

    • Author(s)
      尾松芳樹
    • Organizer
      第42回 日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K06688
  • [Presentation] Niches for hematopoietic stem cells in bone marrow2021

    • Author(s)
      尾松芳樹
    • Organizer
      Virtual Immunology2021 (American Association of Immunologists)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06688
  • [Presentation] 造血幹・前駆細胞ニッチを構成するCAR細胞は骨芽細胞と骨髄脂肪細胞を供給する間葉系幹細胞である2020

    • Author(s)
      尾松芳樹
    • Organizer
      第38回日本骨代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K06688
  • [Presentation] 骨髄:造血の恒常性を担う微小環境の形成と維持の分子基盤2017

    • Author(s)
      尾松芳樹
    • Organizer
      第122回日本解剖学会総会・全国学術集会
    • Place of Presentation
      長崎大学(長崎県長崎市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06232
  • [Presentation] 造血幹細胞・前駆細胞を維持する骨髄のニッチ2016

    • Author(s)
      尾松芳樹
    • Organizer
      第37回 炎症・再生医学会
    • Place of Presentation
      京都市勧業館(京都府京都市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06232
  • [Presentation] 造血幹細胞・前駆細胞を維持するニッチの研究2016

    • Author(s)
      尾松芳樹
    • Organizer
      血小板・巨核球学術講演会
    • Place of Presentation
      ホテルニューオータニ大阪(大阪府大阪市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06232
  • 1.  七野 成之 (70822435)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  佐藤 荘 (60619716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  内藤 尚道 (30570676)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  石亀 晴道 (70729227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  伊藤 美菜子 (70793115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  増田 隆博 (80615287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  田井 育江 (90749508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MORIMOTO Junko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  LEE MICHELLE
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  長澤 丘司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 11.  上出 利光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  依馬 正次
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  高橋 智
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  北澤 理子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  青木 一成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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