Nagashima Takeshi 長嶋剛史

… Alternative Names

NAGASHIMA Takeshi 長嶋剛史

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Researcher Number	80443000
Affiliation (Current)	2025: 静岡県立静岡がんセンター(研究所), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2015: 東北大学, 医学系研究科, 助教 2015: 東北大学, 大学院医学系研究科, 助教 2013: 東北大学, 医学(系)研究科(研究院), 非常勤講師 2013: 東北大学, 大学院医学系研究科, 助教 2012: 東北大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Biological Sciences Except Principal Investigator Tumor biology / General medical chemistry / Carcinogenesis
Keywords	Principal Investigator 核酸代謝 / 細胞周期 / トランスクリプトーム解析 Except Principal Investigator エピジェネティクス / shRNA / スクリーニング / サイレンシング / 転写 / RAS / コンディショナルノックダウン … More / DNAメチル化 / ヒストンメチル化 / SAM合成酵素 / ｓｈRNA / 発がん / ヒストン Less

Molecular mechanism of oncogenic RAS-induced gene silencing
- Principal Investigator
  
  Funayama Ryo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Methods rewriting epigenome as the target of methyonine adenosyltransferase II
- Principal Investigator
  
  KATOH Yasutake
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
細胞増殖の起点となる核酸代謝の亢進のメカニズムの解明Principal Investigator
- Principal Investigator
  
  長嶋剛史
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
A novel role of oncogenic RAS in gene silencing
- Principal Investigator
  
  FUNAYAMA Ryo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  Tohoku University

All 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] The expression of miR-125b-5p is increased in the serum of patients with chronic hepatitis B infection and inhibits the detection of hepatitis B virus surface antigen.2016
- Author(s)
  Ninomiya M, Kondo Y, Kimura O, Funayama R, Nagashima T, Kogure T, Morosawa T, Tanaka Y, Nakayama K, Shimosegawa T.
- Journal Title
  
  J Viral Hepat.
  
  Volume: in press Issue: 5 Pages: 330-9
- DOI
  10.1111/jvh.12522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-16K09335
[Journal Article] Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia.2015
- Author(s)
  Niihori T, Ouchi-Uchiyama M, Sasahara Y, Kaneko T, Hashii Y, Irie M, Sato A, Saito-Nanjo Y, Funayama R, Nagashima T, Inoue S, Nakayama K, Ozono K, Kure S, Matsubara Y, Imaizumi M, Aoki Y.
- Journal Title
  
  Am J Hum Genet.
  
  Volume: 97 Issue: 6 Pages: 848-854
- DOI
  10.1016/j.ajhg.2015.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26461562, KAKENHI-PROJECT-26830064
[Journal Article] The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes.2015
- Author(s)
  Wong WF, Kohu K, Nagashima T, Funayama R, Matsumoto M, Movahed E, Tan GM, Yeow TC, Looi CY, Kurokawa M, Osato M, Igarashi K, Nakayama K, Satake M.
- Journal Title
  
  Mol Immunol.
  
  Volume: 68 Issue: 2 Pages: 223-33
- DOI
  10.1016/j.molimm.2015.08.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04312, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-26293059
[Journal Article] Mutations in PIGL in a patient with Mabry syndrome.2015
- Author(s)
  Fujiwara I, Murakami Y, Niihori T, Kanno J, Hakoda A, Sakamoto O, Okamoto N, Funayama R, Nagashima T, Nakayama K, Kinoshita T, Kure S, Matsubara Y, Aoki Y.
- Journal Title
  
  Am J Med Genet A.
  
  Volume: in press Issue: 4 Pages: 777-785
- DOI
  10.1002/ajmg.a.36987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25129705, KAKENHI-PROJECT-25461535, KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059
[Journal Article] RNA sequencing-based identification of aberrant imprinting in cloned mice.2014
- Author(s)
  Okae H, Matoba S, Nagashima T, Mizutani E, Inoue K, Ogonuki N, Chiba H, Funayama R, Tanaka S, Yaegashi N, Nakayama K, Sasaki H, Ogura A, Arima T.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 Issue: 4 Pages: 992-1001
- DOI
  10.1093/hmg/ddt495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390385, KAKENHI-PROJECT-23500507, KAKENHI-PUBLICLY-24116503, KAKENHI-PROJECT-24700951, KAKENHI-PROJECT-24780277, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112009, KAKENHI-PLANNED-25112010
[Journal Article] HCV infection enhances Th17 commitment, which could affect the pathogenesis of autoimmune diseases2014
- Author(s)
  Kondo Y, Ninomiya M, Kimura O, Machida K, Funayama R, Nagashima T, Kobayashi K, Kakazu E, Kato T, Nakayama K, Lai MM, Shimosegawa T.
- Journal Title
  
  PLoS One
  
  Volume: 9(6) Issue: 6 Pages: e98521-e98521
- DOI
  10.1371/journal.pone.0098521
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460970, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26670085, KAKENHI-PROJECT-26830064
[Journal Article] GNE myopathy associated with congenital thrombocytopenia: a report of two siblings.2014
- Author(s)
  Izumi R, Niihori T, Suzuki N, Sasahara Y, Nishiyama A, Nishiyama S, Endo K, Kato M, Warita H, Konno H, Tateyama M, Nagashima T, Funayama R, Nakayama K, Kure S, Matsubara Y, Aoki Y, Aoki M.
- Journal Title
  
  Neuromuscul. Disord.
  
  Volume: 24(12) Issue: 12 Pages: 1068-1072
- DOI
  10.1016/j.nmd.2014.07.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591528, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26461562, KAKENHI-PROJECT-26670085, KAKENHI-PROJECT-26830064
[Journal Article] TBX1 Mutation Identified by Exome Sequencing in a Japanese Family with 22q11.2 Deletion Syndrome-like Craniofacial Features and Hypocalcemia.2014
- Author(s)
  Ogata T*, Niihori T, Tanaka N, Kawai M, Nagashima T, Funayama R, Nakayama K, Nakashim S, Kato F, Fukami M, Aoki Y, Matsubara Y
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 3 Pages: e91598-e91598
- DOI
  10.1371/journal.pone.0091598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-23390268, KAKENHI-PROJECT-23791148, KAKENHI-PLANNED-24119005, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-26830064
[Journal Article] Ras-Induced Changes in H3K27me3 Occur after Those in Transcriptional Activity2013
- Author(s)
  Hosogane M, Funayama R, Nishida Y, Nagashima T, Nakayama K.
- Journal Title
  
  PLoS Genet.
  
  Volume: 9 Issue: 8 Pages: e1003698-e1003698
- DOI
  10.1371/journal.pgen.1003698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700951
[Journal Article] Distinct MicroRNAs Expression Profile in Primary Biliary Cirrhosis and Evaluation of miR 505-3p and miR197-3p as Novel Biomarkers2013
- Author(s)
  Ninomiya, M., Kondo, Y., Funayama, R., Nagashima, T., Kogure, T., Kakazu, E., Kimura, O., Ueno, Y., Nakayama, K., Shimosegawa, T.
- Journal Title
  
  PloS one
  
  Volume: 8 Issue: 6 Pages: e66086-e66086
- DOI
  10.1371/journal.pone.0066086
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24116503, KAKENHI-PROJECT-24700951, KAKENHI-PROJECT-25460970
[Journal Article] Exome sequencing identifies a novel TTN mutation in a family with hereditary myopathy with early respiratory failure2013
- Author(s)
  Izumi R, Niihori T, Aoki Y, Suzuki N, Kato M, Warita H, Takahashi T, Tateyama M, Nagashima T, Funayama R, Abe K, Nakayama K, Aoki M, Matsubara Y
- Journal Title
  
  J Hum Genet
  
  Volume: 58(5) Issue: 5 Pages: 259-66
- DOI
  10.1038/jhg.2013.9
- NAID
  10031177220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390268, KAKENHI-PROJECT-23591229, KAKENHI-PROJECT-23659513, KAKENHI-PROJECT-23791148, KAKENHI-PUBLICLY-24116503, KAKENHI-PROJECT-24659421, KAKENHI-PROJECT-24700951
[Journal Article] Gain-of-Function Mutations in RIT1 Cause Noonan Syndrome, a RAS/MAPK Pathway Syndrome2013
- Author(s)
  Aoki Y, Niihori T, Banio T, Okamoto N, Mizuno S, Kurosawa K, Ogata T, Takada F, Yano M, Ando T, Hoshika T, Barnett C, Ohashi H, Kawame H, Hasegawa T, Okutani T, Nagashima T, Hasegawa S, Funayama R, Nagashima T Nakayama K, Inoue S, Watanabe Y, Oeura T, Matsubara Y
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: Volume 93, Issue 1 Issue: 1 Pages: 173-180
- DOI
  10.1016/j.ajhg.2013.05.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08517, KAKENHI-PLANNED-22127006, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-23390268, KAKENHI-PROJECT-23791148, KAKENHI-PUBLICLY-24116503, KAKENHI-PUBLICLY-24116701, KAKENHI-PROJECT-24370085, KAKENHI-PROJECT-24657127, KAKENHI-PROJECT-24700951, KAKENHI-PROJECT-24790189
[Journal Article] 高感度に多型を検出するためのエキソーム・シークエンシング2012
- Author(s)
  舟山亮, 長嶋剛史, 中山啓子
- Journal Title
  
  実験医学
  
  Volume: 30 Pages: 629-34
- URL
  https://www.yodosha.co.jp/jikkenigaku/book/9784758100816/index.html
- Data Source
  KAKENHI-PROJECT-24700951
[Journal Article] Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks2012
- Author(s)
  Hirotsu Y, Katsuoka F, Funayama R, Nagashima T, Nishida Y, Nakayama K, Engel JD, Yamamoto M.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 40 Issue: 20 Pages: 10228-10239
- DOI
  10.1093/nar/gks827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07842, KAKENHI-PROJECT-23790351, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24700951
[Journal Article] Use of illumina deep sequencing technology to differentiate hepatitis Cvirus variants2012
- Author(s)
  Ninomiya M, Ueno Y, Funayama R, Kagashima T, Nishida Y, Kondo Y, Inoue J, Kakazu E, Kimura O, Nakayama K, Shimosegawa T
- Journal Title
  
  Journal of clinical microbiology
  
  Volume: 50 Issue: 3 Pages: 857-866
- DOI
  10.1128/jcm.05715-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590822, KAKENHI-PROJECT-23790761, KAKENHI-PROJECT-23790762, KAKENHI-PROJECT-23790765, KAKENHI-PROJECT-24700951
[Presentation] がん原遺伝子RASによる遺伝子サイレンシングの分子機構の解析.2015
- Author(s)
  舟山亮, 細金正樹, 長嶋剛史, 中山啓子.
- Organizer
  第38回日本分子生物学会年会.
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830064
[Presentation] Change of Trimethylation of H3K27 Occurs after Ras-mediated Transcriptional Regulation2013
- Author(s)
  Nakayama, K., Hosogane, M., Funayama, R., Nagashima, T.
- Organizer
  NIH-Tohoku University-JSPS Symposium
- Place of Presentation
  仙台
- Year and Date
  2013-05-09
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Comprehensive Analysis of Ras-Mediated Alternative Splicing2013
- Author(s)
  Matsushima, W., Funayama, R., Nagashima, T., Nakayama, K.
- Organizer
  NIH-Tohoku University-JSPS Symposium
- Place of Presentation
  仙台
- Year and Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Ras-MAPKシグナルを介したFas遺伝子の転写抑制機構の解析2013
- Author(s)
  舟山亮, 細金正樹, 長嶋剛史, 中山啓子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] がん遺伝子Rasによる転写変化後のH3K27me3修飾変化2013
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 長嶋剛史, 中山啓子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] がん遺伝子Rasによる転写制御後にH3K27me3修飾変化が誘起される2012
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 長嶋剛史, 中山啓子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Change of trimethylation of H3K27 occurs after Ras-mediated transcriptional regulation2012
- Author(s)
  Hosogane, M., Funayama, R., Nishida, Y., Nagashima, T., Nakayama, K.
- Organizer
  Winter Camp of GCOE 2012, Tohoku University Global COE for Conquest of Signal Transduction Diseases with"Network Medicine"
- Place of Presentation
  仙台
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] RASシグナルによる選択的スプライシング変化の網羅的解析2012
- Author(s)
  松島和洋, 舟山亮, 長嶋剛史, 中山啓子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Comprehensive analysis of altemative splicing by next-generation sequencer2012
- Author(s)
  Matsushima, W., Funayama, R., Nagashima, T., Nakayama, K.
- Organizer
  Winter Camp of GCOE 2012, Tohoku University Global COE for Conquest of Signal Transduction Diseases with"Network Medicine"
- Place of Presentation
  仙台
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] shRNAライブラリのスクリーニングによる遺伝子サイレンシング機構の解析2012
- Author(s)
  舟山亮, 細金正樹, 長嶋剛史, 中山啓子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Nrf2-小Maf転写因子のゲノムワイド解析による遺伝子発現制御システムの解明2012
- Author(s)
  弘津陽介, 勝岡史城, 舟山亮, 長嶋剛史, 西田有一郎, 中山啓子, ジェームスダグラスエンゲル, 山本雅之
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] RASシグナルによる選択的スプライシング変化の網羅的解析2012
- Author(s)
  松島和洋, 舟山亮, 長嶋剛史, 中山啓子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] がん遺伝子Rasによる転写制御後にH3K27me3修飾変化が誘起される2012
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 長嶋剛史, 中山啓子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] shRNAライブラリのスクリーニングによる遺伝子サイレンシング機構の解析2012
- Author(s)
  舟山亮, 細金正樹, 長嶋剛史, 中山啓子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Change of Trimethylation of H3K27 Occurs after Ras-mediated Transcriptional Regulation
- Author(s)
  Nakayama, K., Hosogane, M., Funayama, R., Nagashima, T.
- Organizer
  NIH-Tohoku University-JSPS Symposium
- Place of Presentation
  艮陵会館（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Ras-MAPKシグナルを介したFas遺伝子の転写抑制機構の解析
- Author(s)
  舟山亮, 細金正樹, 長嶋剛史, 中山啓子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Ras-MAPKシグナルを介したFas遺伝子の転写抑制機構の解析
- Author(s)
  舟山　亮, 細金　正樹, 長嶋　剛史, 中山　啓子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Data Source
  KAKENHI-PUBLICLY-24116503
[Presentation] Comprehensive Analysis of Ras-Mediated Alternative Splicing
- Author(s)
  Matsushima, W., Funayama, R., Nagashima, T., Nakayama, K.
- Organizer
  NIH-Tohoku University-JSPS Symposium
- Place of Presentation
  艮陵会館（宮城県仙台市）
- Data Source
  KAKENHI-PUBLICLY-24116503
[Presentation] がん遺伝子Rasによる転写変化後のH3K27me3修飾変化
- Author(s)
  細金　正樹, 舟山　亮, 西田　有一郎, 長嶋　剛史, 中山　啓子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Data Source
  KAKENHI-PUBLICLY-24116503
[Presentation] Change of Trimethylation of H3K27 Occurs after Ras-mediated Transcriptional Regulation
- Author(s)
  Nakayama, K., Hosogane, M., Funayama, R., Nagashima, T.
- Organizer
  NIH-Tohoku University-JSPS Symposium
- Place of Presentation
  艮陵会館（宮城県仙台市）
- Data Source
  KAKENHI-PUBLICLY-24116503
[Presentation] がん遺伝子Rasによる転写変化後のH3K27me3修飾変化
- Author(s)
  細金正樹, 舟山亮, 西田有一郎, 長嶋剛史, 中山啓子
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-24700951
[Presentation] Comprehensive Analysis of Ras-Mediated Alternative Splicing
- Author(s)
  Matsushima, W., Funayama, R., Nagashima, T., Nakayama, K.
- Organizer
  NIH-Tohoku University-JSPS Symposium
- Place of Presentation
  艮陵会館（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24700951

1. FUNAYAMA Ryo (20452295)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
2. HOSOGANE Masaki (30734347)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. KATOH Yasutake (40397914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MORITA Masanobu (10519094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SAIGUSA Daisuke (90545237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUMOTO Mitsuyo (80400448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAYAMA Keiko (60294972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. NIIHORI Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. KONDO Yasuteru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. KAKAZU Eiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MURAKAMI Yoshiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. OGATA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. FUKAMI Maki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 青木洋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 松原洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 有馬隆博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 岡江寛明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 八重樫伸生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 大里元美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 上野義之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 笹原洋二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagashima Takeshi 長嶋 剛史

NAGASHIMA Takeshi 長嶋 剛史

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Molecular mechanism of oncogenic RAS-induced gene silencing

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Methods rewriting epigenome as the target of methyonine adenosyltransferase II

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細胞増殖の起点となる核酸代謝の亢進のメカニズムの解明Principal Investigator

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A novel role of oncogenic RAS in gene silencing

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[Journal Article] The expression of miR-125b-5p is increased in the serum of patients with chronic hepatitis B infection and inhibits the detection of hepatitis B virus surface antigen.2016

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[Journal Article] Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia.2015

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[Journal Article] The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes.2015

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[Journal Article] Mutations in PIGL in a patient with Mabry syndrome.2015

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[Journal Article] RNA sequencing-based identification of aberrant imprinting in cloned mice.2014

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[Journal Article] HCV infection enhances Th17 commitment, which could affect the pathogenesis of autoimmune diseases2014

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[Journal Article] GNE myopathy associated with congenital thrombocytopenia: a report of two siblings.2014

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[Journal Article] TBX1 Mutation Identified by Exome Sequencing in a Japanese Family with 22q11.2 Deletion Syndrome-like Craniofacial Features and Hypocalcemia.2014

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[Journal Article] Ras-Induced Changes in H3K27me3 Occur after Those in Transcriptional Activity2013

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[Journal Article] Distinct MicroRNAs Expression Profile in Primary Biliary Cirrhosis and Evaluation of miR 505-3p and miR197-3p as Novel Biomarkers2013

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[Journal Article] Exome sequencing identifies a novel TTN mutation in a family with hereditary myopathy with early respiratory failure2013

Nagashima Takeshi 長嶋剛史

NAGASHIMA Takeshi 長嶋剛史