MAEDA Kengo 前田健吾

Researcher Number	80456673
Other IDs
Affiliation (based on the past Project Information) *help	2014: 名古屋大学, 医学部附属病院, 講師 2007 – 2013: Nagoya University, University Hospital, Assistant Associate 2010: 名古屋大学, 医学部付属病院, 助教 2009: 名古屋大学, 医学部・附属病院, 助教 2009: 名大, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator Girdin / Ｇｉｒｄｉｎ / Ｇｉｐｉｅ / neointima / permeability / Gipie / 細胞骨格制御 / 細胞骨格 / Akt / 新生内膜 … More Except Principal Investigator … More 心不全 / heart failure / myocardial fibrosis / atrial fibrillation / PPAR γ activator / 心房筋線維化 / PARγアゴニスト / 心筋線維化 / 心房細動 / PRARγアゴニスト / 高インスリン血症 / 心筋症 / 糖尿病性毛細血管傷害 / 高血糖 / 心筋リモデリング / ミトコンドリア / 心筋繊維化 / インスリン抵抗性 / 蛋白分解酵素 / 細胞内シグナル / 血管再生 / 再生医学 / 血管新生 / 糖尿病性心筋症 / 糖尿病 Less

新規Ａｋｔ基質Ｇｉｒｄｉｎファミリー分子の制御による動脈硬化抑制の試みPrincipal Investigator
- Principal Investigator
  
  前田健吾
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Nagoya University
The role of Girdin, a new Akt substrate, in vascular homeostasisPrincipal Investigator
- Principal Investigator
  
  MAEDA Kengo
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nagoya University
Role of diseased angiogenesis in diabetic cardiomyopathy and its significance for the invention of novel therapeutic strategy.
- Principal Investigator
  
  MUROHARA Toyoaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nagoya University
新規Akt基質Girdinの制御による血管新生内膜の抑制Principal Investigator
- Principal Investigator
  
  前田健吾
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nagoya University
Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation-promotion
- Principal Investigator
  
  INDEN Yasuya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nagoya University

All 2015 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] New endoplasmic reticulum stress regulator, gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury.2015
- Author(s)
  Noda T, Maeda K, Hayano S, Asai N, Enomoto A, Takahashi M, Murohara T
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 35 Issue: 5 Pages: 1246-1253
- DOI
  10.1161/atvbaha.114.304923
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461124, KAKENHI-PROJECT-26293184, KAKENHI-PROJECT-26221304
[Journal Article] Akt-girdin signaling in cancer-associated fibroblasts contributes to tumor progression2015
- Author(s)
  Yumiko Yamamura, Naoya Asai, Atsushi Enomoto, Takuya Kato, Shinji Mii, Yuji Kondo, Kaori Ushida, Kaoru Niimi, Nobuyuki Tsunoda, Masato Nagino, Shu Ichihara, Koichi Furukawa, Kengo Maeda, Toyoaki Murohara, Masahide Takahashi
- Journal Title
  
  Cancer Research
  
  Volume: 75 Issue: 5 Pages: 813-823
- DOI
  10.1158/0008-5472.can-14-1317
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25461124, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-25860293, KAKENHI-PROJECT-15K15080, KAKENHI-PROJECT-26221304
[Journal Article] Girdin/GIV regulates transendothelial permeability by controlling VE-cadherin trafficking through the small GTPase, R-Ras.2015
- Author(s)
  Ichimiya H, Maeda K, Enomoto A, Weng L, Takahashi M, Murohara T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 461 Issue: 2 Pages: 260-267
- DOI
  10.1016/j.bbrc.2015.04.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461124, KAKENHI-PROJECT-15K21061, KAKENHI-PROJECT-26293184, KAKENHI-PROJECT-26221304
[Journal Article] Impact of adiponectin and leptin on long-term adverse events in Japanese patients with acute myocardial infarction. Results from the Nagoya Acute Myocardial Infarction Study (NAMIS).2013
- Author(s)
  Morita Y, Maeda K, Kondo T, Ishii H, Matsudaira K, Okumura N, Mitsuhashi H, Shibata R, Murohara T; Nagoya Acute Myocardial Infarction Study (NAMIS) Group.
- Journal Title
  
  Ｃｉｒｖｕｌａｔｉｏｎ　Ｊｏｕｒｎａｌ
  
  Volume: 77(11) Pages: 2778-2785
- NAID
  10031196831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461124
[Journal Article] Therapeutic Reendothelialization by Induced Pluripotent Stem Cells After Vascular Injury2013
- Author(s)
  Yamamoto T, Shibata R, Ishii M, Kanemura N, Kito T, Suzuki H, Miyake H, Maeda K, Tanigawa T, Ouchi N, Murohara T
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 33 Issue: 9 Pages: 2218-21
- DOI
  10.1161/atvbaha.113.301313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390207, KAKENHI-PROJECT-23390208, KAKENHI-PROJECT-23790845, KAKENHI-PROJECT-24659384, KAKENHI-PROJECT-25461124, KAKENHI-PROJECT-25860595
[Journal Article] The significance of measuring body fat percentage determined by bioelectrical impedance analysis for detecting subjects with cardiovascular disease risk factors2012
- Author(s)
  Yamashita K, Kondo T, Osugi S, Shimokata K, Maeda K, Okumura N, Matsudaira K, Shintani S, Muramatsu T, Matsushita K, Murohara T
- Journal Title
  
  Circ J
  
  Volume: 76(10) Pages: 2435-42
- NAID
  10030875041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance : NAGOYA HEART Study2012
- Author(s)
  Muramatsu T, Matsushita K, Yamashita K, Kondo T, Maeda K, Shintani S, Ichimiya S, Ohno M, Sone T, Ikeda N, Watarai M, Murohara T; NAGOYA HEART Study Investigators
- Journal Title
  
  Hypertension
  
  Volume: 59(3) Pages: 580-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Efficacy and safety of the losartan-hydrochlorothiazide combination tablet in patients with hypertension uncontrolled by angiotensin II receptor antagonist therapy: the Aichi Research on Combination therapy for Hypertension (ARCH) Study.2012
- Author(s)
  Maeda K
- Journal Title
  
  Internal Medicine
  
  Volume: 51 Pages: 1167-1175
- NAID
  130002062442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Impact of low levels of vascular endothelial growth factor after myocardial infarction on 6-month clinical outcome. Results from the Nagoya Acute Myocardial Infarction Study2012
- Author(s)
  Matsudaira K, Maeda K, Okumura N, Yoshikawa D, Morita Y, Mitsuhashi H, Ishii H, Kondo T, Murohara T; Nagoya Acute Myocardial Infarction Study (NAMIS) Group
- Journal Title
  
  Circ J
  
  Volume: 76(6) Pages: 1509-16
- NAID
  10030316626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Efficacy and safety of the losartan-hydrochlorothiazide combination tablet in patients with hypertension uncontrolled by angiotensin II receptor antagonist therapy : the Aichi Research on Combination therapy for Hypertension (ARCH) Study2012
- Author(s)
  Maeda K, Adachi M, Kinoshita A, Koh N, Miura Y, Murohara T
- Journal Title
  
  Intern Med
  
  Volume: 51(10) Pages: 1167-75
- NAID
  130002062442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Metabolic syndrome and all-cause mortality, cardiac events, and cardiovascular events : a follow-up study in 25, 471 young- and middle-aged Japanese men2011
- Author(s)
  Kondo T, Osugi S, Shimokata K, Honjo H, Morita Y, Yamashita K, Maeda K, Muramatsu T, Shintani S, Matsushita K, Murohara T
- Journal Title
  
  Eur J Cardiovasc Prev Rehabil
  
  Volume: 18(4) Pages: 574-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury2011
- Author(s)
  Miyake H, Maeda K, Asai N, Shibata R, Ichimiya H, Isotani-Sakakibara M, Yamamura Y, Kato K, Enomoto A, Takahashi M, Murohara T
- Journal Title
  
  Circ Res
  
  Volume: 108(10) Pages: 1170-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cells2011
- Author(s)
  Matsushita E, Asai N, Enomoto A, Kawamoto Y, Kato T, Mii S, Maeda K, Shibata R, Hattori S, Hagikura M, Takahashi K, Sokabe M, Murakumo Y, Murohara T, Takahashi M
- Journal Title
  
  Mol Biol Cell
  
  Volume: 22(6) Pages: 736-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Smoking and smoking cessation in relation to all-cause mortality and cardiovascular events in 25, 464 healthy male Japanese workers2011
- Author(s)
  Kondo T, Osugi S, Shimokata K, Honjo H, Morita Y, Maeda K, Yamashita K, Muramatsu T, Shintani S, Matsushita K, Murohara T
- Journal Title
  
  Circ J
  
  Volume: 75(12) Pages: 2885-92
- NAID
  10030033623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Pitavastatin, an HMG-CoA reductase inhibitor, ameliorates endothelial function in chronic smokers2010
- Author(s)
  Yoshida O, Kondo T, Kureishi-Bando Y, Sugiura T, Maeda K, Okumura K, Murohara T
- Journal Title
  
  Circ J
  
  Volume: 74(1) Pages: 195-202
- NAID
  10025941804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Rationale and design of the NAGOYA HEART Study : comparison between valsartan and amlodipine regarding morbidity and mortality in patients with hypertension and glucose intolerance2010
- Author(s)
  Matsushita K, Muramatsu T, Kondo T, Maeda K, Shintani S, Murohara T; NAGOYA HEART Study Group
- Journal Title
  
  J Cardiol
  
  Volume: 56(1) Pages: 111-7
- NAID
  10027703831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790715
[Journal Article] Caloric restriction stimulates revascularization in response to ischemia via adiponectin-mediated activation of eNOS2009
- Author(s)
  Kondo M, Shibata R, Miura R, Shimano M, Kondo K, Li P, Ohashi T, Kihara S, Maeda N, Walsh K, Ouchi N, Murohara T.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 1718-1724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249045
[Journal Article] わが国における急性心筋梗塞診療の現状と課題-多施設共同研究から-2008
- Author(s)
  近藤隆久, 森田康弘, 前田健吾, 石井秀樹, 室原豊明
- Journal Title
  
  冠疾患誌 14
  
  Pages: 154-158
- Data Source
  KAKENHI-PROJECT-20890095
[Journal Article] Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.2008
- Author(s)
  Kitamura T, Asai N, Enomoto A, Maeda K, Kato T, Ishida M, Jiang P, Watanabe T, Usukura J, Kondo T, Costantini F, Murohara T, Takahashi M.
- Journal Title
  
  Nat.Cell Biol. 10
  
  Pages: 329-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249045
[Presentation] Actin binding protein Girdin/Ccdc88a regulates vascular permeability via interaction with Rras2011
- Author(s)
  前田健吾
- Organizer
  日本循環器学会
- Place of Presentation
  横浜
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-21790715
[Presentation] Actin binding protein Girdin/Ccdc88a regulates vascular permeability via interaction with Rras2011
- Author(s)
  Kengo Maeda, Hitoshi Ichimiya1, Hiroshi Miyake, Atsushi Enomoto, Masahide Takahashi, Toyoaki Murohara
- Organizer
  日本循環器学会総会
- Place of Presentation
  パシフィコ横浜横浜市
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-21790715
[Presentation] Akt/PKB Substrate Girdin Has an Impact on the Neointimal Formation by Regulating Migration and Proliferation of VSMCs2010
- Author(s)
  Hiroshi Miyake, Kengo Maeda,Tomoya Kitamura1, Rei Shibata1,Atsushi Enomoto, Masahide Takahashi, Toyoaki Murohara
- Organizer
  日本循環器学会総会
- Place of Presentation
  京都国際会議場京都市
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-21790715
[Presentation] 新規Akt基質 Girdinによる血管新生の制御2009
- Author(s)
  前田健吾
- Organizer
  第50回日本脈管学会総会シンポジウム 2循環器内科系内皮と脈管疾患
- Place of Presentation
  ハイアットリージェンシー東京東京都
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-21790715
[Presentation] Regulation of VEGF-mediated angiogenesis by the Akt/PKB Substrate Girdin2008
- Author(s)
  前田健吾
- Organizer
  The 25^<th> Annual Meeting of ISHR Japanease Section
- Place of Presentation
  横浜
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20890095
[Presentation] Girdin and its phosphorylation regulate repair process after acute myocardial infarction
- Author(s)
  Hayano S, Maeda K, Enomono A, Kobayashi K, Takahashi M, Murohara T
- Organizer
  The 31st Annual Meeting of the International Society for Heart Research Japanese Section
- Place of Presentation
  ウインク愛知（愛知県名古屋市）
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-25461124
[Presentation] A New Er Stress Regulator, Gipie, Regulates the Survivability of Vacsular Smooth Muscle Cells and the Neointima Formation
- Author(s)
  Noda T, Maeda K, Hayano S, Asai N, Enomoto A, Takahashi M, Murohara T
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場他（大阪府大阪市）
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-25461124

1. MUROHARA Toyoaki (90299503)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. SHINTANI Satoshi (20309777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. BANDO Yasuko (60452190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHIBATA Rei (70343689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. TAKESHITA Kyosuke (70444403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. INDEN Yasuya (10359747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TSUJI Yukiomi (60432217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 沼口靖 (90378224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 近藤隆久 (00303644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OUCHI NORIYUKI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. ENOMOTO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 浅井直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 高橋雅英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MAEDA Kengo 前田 健吾

Research Projects

Research Products

Co-Researchers

新規Ａｋｔ基質Ｇｉｒｄｉｎファミリー分子の制御による動脈硬化抑制の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Girdin, a new Akt substrate, in vascular homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of diseased angiogenesis in diabetic cardiomyopathy and its significance for the invention of novel therapeutic strategy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規Akt基質Girdinの制御による血管新生内膜の抑制Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation-promotion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] New endoplasmic reticulum stress regulator, gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Akt-girdin signaling in cancer-associated fibroblasts contributes to tumor progression2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Girdin/GIV regulates transendothelial permeability by controlling VE-cadherin trafficking through the small GTPase, R-Ras.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of adiponectin and leptin on long-term adverse events in Japanese patients with acute myocardial infarction. Results from the Nagoya Acute Myocardial Infarction Study (NAMIS).2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Therapeutic Reendothelialization by Induced Pluripotent Stem Cells After Vascular Injury2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The significance of measuring body fat percentage determined by bioelectrical impedance analysis for detecting subjects with cardiovascular disease risk factors2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance : NAGOYA HEART Study2012

Author(s)

Journal Title

Data Source

[Journal Article] Efficacy and safety of the losartan-hydrochlorothiazide combination tablet in patients with hypertension uncontrolled by angiotensin II receptor antagonist therapy: the Aichi Research on Combination therapy for Hypertension (ARCH) Study.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Impact of low levels of vascular endothelial growth factor after myocardial infarction on 6-month clinical outcome. Results from the Nagoya Acute Myocardial Infarction Study2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Efficacy and safety of the losartan-hydrochlorothiazide combination tablet in patients with hypertension uncontrolled by angiotensin II receptor antagonist therapy : the Aichi Research on Combination therapy for Hypertension (ARCH) Study2012

Author(s)

MAEDA Kengo 前田健吾