Oshima Atsunori 大嶋篤典

… Alternative Names

OHSHIMA Atsunori 大嶋篤典

Less

Researcher Number	80456847
Other IDs
Affiliation (Current)	2025: 名古屋大学, 細胞生理学研究センター, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 名古屋大学, 細胞生理学研究センター, 教授 2014 – 2016: 名古屋大学, 細胞生理学研究センター, 准教授 2015: 名古屋大学, 名古屋大学細胞生理学研究センター, 准教授 2014: 名古屋大学, 大学院創薬科学研究科/細胞生理学研究センター, 准教授
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Structural biochemistry / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields Except Principal Investigator Biophysics
Keywords	Principal Investigator クライオ電子顕微鏡 / 試料調製 / 開閉メカニズム / 高分解能構造解析 / ギャップ結合チャネル / 脂質膜再構成 / large pore channel / ナノディスク再構成 / 単粒子解析 / 電子顕微鏡 … More / イネキシン / 分子動力学 / 膜透過機構 / ギャップ結合関連タンパク質 / ゲーティングモデル / Large Pore Channel / リポソーム / コネキシン / 3D variability解析 / チャネル機能解析 / タンパク質―脂質相互作用 / 原子モデル / 高分解能単粒子解析 / ナノディスク / 二次元結晶化 / 極低温電子顕微鏡 / 二次元結晶 / 三次元再構成 … More Except Principal Investigator 膜タンパク質 / 電子線結晶学 / 膜タンパク質の生理機能 / 単粒子解析法 / 構造生物学 / 結晶学 / 単粒子解析 / チャネル / 構造生理学 / クライオ電子顕微鏡 / プロトンポンプ / 構造解析 / ナトリウムチャネル / H+,K+-ATPase / アセチルコリン受容体 / クローディン / ギャップ結合チャネル / イオンチャネル / 水チャネル Less

Membrane permeation mechanism mediated by large pore channels contributed by phospholipidsPrincipal Investigator
- Principal Investigator
  
  大嶋篤典
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Nagoya University
A novel gating model for a large pore channel in a lipid bilayerPrincipal Investigator
- Principal Investigator
  
  大嶋篤典
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Nagoya University
Cryo-EM analysis of intercellular junction channels of higher animalsPrincipal Investigator
- Principal Investigator
  
  Oshima Atsunori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Nagoya University
High-resolution single particle analysis of intercellular channelsPrincipal Investigator
- Principal Investigator
  
  Oshima Atsunori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya University
Studies in structural physiology of channels
- Principal Investigator
  
  FUJIYOSHI Yoshinori
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biophysics
- Research Institution
  Tokyo Medical and Dental University
  Nagoya University
Structural and functional analysis of gap junction channels using electron microscopyPrincipal Investigator
- Principal Investigator
  
  Oshima Atsunori
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya University
Structural and functional study of membrane proteins based on electron crystallography
- Principal Investigator
  
  FUJIYOSHI Yoshinori
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
  Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2011 Other

All Journal Article Presentation

[Journal Article] Structures and Gating Mechanism of Large Pore Channels2023
- Author(s)
  大嶋篤典
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 63 Issue: 2 Pages: 97-101
- DOI
  10.2142/biophys.63.97
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19H03165
[Journal Article] Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit2023
- Author(s)
  Kozai Daisuke、Numoto Nobutaka、Nishikawa Kouki、Kamegawa Akiko、Kawasaki Shohei、Hiroaki Yoko、Irie Katsumasa、Oshima Atsunori、Hanzawa Hiroyuki、Shimada Kousei、Kitano Yutaka、Fujiyoshi Yoshinori
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 435 Issue: 10 Pages: 168049-168049
- DOI
  10.1016/j.jmb.2023.168049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-20K09193, KAKENHI-PROJECT-19H03165
[Journal Article] Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding2023
- Author(s)
  S. Suzuki, K. Tanaka, K. Nishikawa, H. Suzuki, A. Oshima, Y. Fujiyoshi
- Journal Title
  
  Nat. Commun.
  
  Volume: 14 Issue: 1 Pages: 5899-5899
- DOI
  10.1038/s41467-023-41650-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-20H00451
[Journal Article] Structure and function of H+/K+ pump mutants reveal Na+/K+ pump mechanisms2022
- Author(s)
  Young Victoria C.、Nakanishi Hanayo、Meyer Dylan J.、Nishizawa Tomohiro、Oshima Atsunori、Artigas Pablo、Abe Kazuhiro
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 5270-5270
- DOI
  10.1038/s41467-022-32793-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03165, KAKENHI-PROJECT-21H02426
[Journal Article] Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump2022
- Author(s)
  Tanaka Saki、Morita Mikio、Yamagishi Tatsuya、Madapally Hridya Valia、Hayashida Kenichi、Khandelia Himanshu、Gerle Christoph、Shigematsu Hideki、Oshima Atsunori、Abe Kazuhiro
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 65 Issue: 11 Pages: 7843-7853
- DOI
  10.1021/acs.jmedchem.2c00338
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-19H03165, KAKENHI-PROJECT-21H02426
[Journal Article] A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly2022
- Author(s)
  Kataoka Koki、Suzuki Shota、Tenno Takeshi、Goda Natsuko、Hibino Emi、Oshima Atsunori、Hiroaki Hidekazu
- Journal Title
  
  Current Research in Structural Biology
  
  Volume: 4 Pages: 158-166
- DOI
  10.1016/j.crstbi.2022.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-19H03165
[Journal Article] Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution2022
- Author(s)
  Akil Caner、Ali Samson、Tran Linh T.、Gaillard J?r?mie、Li Wenfei、Hayashida Kenichi、Hirose Mika、Kato Takayuki、Oshima Atsunori、Fujishima Kosuke、Blanchoin Laurent、Narita Akihiro、Robinson Robert C.
- Journal Title
  
  Science Advances
  
  Volume: 8 Issue: 12
- DOI
  10.1126/sciadv.abm2225
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-19H03165
[Journal Article] Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 22022
- Author(s)
  Nakanishi Hanayo、Hayashida Kenichi、Nishizawa Tomohiro、Oshima Atsunori、Abe Kazuhiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 1 Pages: 101498-101498
- DOI
  10.1016/j.jbc.2021.101498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06064, KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-21H02426
[Journal Article] Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM2022
- Author(s)
  Suzuki Shota、Iida Momoko、Hiroaki Yoko、Tanaka Kotaro、Kawamoto Akihiro、Kato Takayuki、Oshima Atsunori
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 707-707
- DOI
  10.1038/s42003-022-03668-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-19H03165
[Journal Article] Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids2022
- Author(s)
  Kuzuya Maki、Hirano Hidemi、Hayashida Kenichi、Watanabe Masakatsu、Kobayashi Kazumi、Terada Tohru、Mahmood Md. Iqbal、Tama Florence、Tani Kazutoshi、Fujiyoshi Yoshinori、Oshima Atsunori
- Journal Title
  
  Science Signaling
  
  Volume: 15 Issue: 720
- DOI
  10.1126/scisignal.abg6941
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03683, KAKENHI-PROJECT-19H03165, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-21K19215
[Journal Article] Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations2021
- Author(s)
  Abe Kazuhiro、Yamamoto Kenta、Irie Katsumasa、Nishizawa Tomohiro、Oshima Atsunori
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 5709-5709
- DOI
  10.1038/s41467-021-26024-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-20K09193, KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-21H02426
[Journal Article] Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids2020
- Author(s)
  Burendei Batuujin、Shinozaki Ruriko、Watanabe Masakatsu、Terada Tohru、Tani Kazutoshi、Fujiyoshi Yoshinori、Oshima Atsunori
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 7
- DOI
  10.1126/sciadv.aax3157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-19H03165, KAKENHI-PROJECT-17K19347, KAKENHI-PROJECT-17H03683
[Journal Article] Potential of cryo-EM for high-resolution structural analysis of gap junction channels2019
- Author(s)
  Atsunori Oshima
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 54 Pages: 28-85
- DOI
  10.1016/j.sbi.2019.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07266
[Journal Article] クライオ電子顕微鏡で見るギャップ結合チャネルの構造2019
- Author(s)
  大嶋篤典
- Journal Title
  
  細胞
  
  Volume: 51 Pages: 8-11
- Data Source
  KAKENHI-PROJECT-19H03165
[Journal Article] Structure of an innexin gap junction channel and cryo-EM sample preparation2017
- Author(s)
  Oshima Atsunori
- Journal Title
  
  Microscopy
  
  Volume: 66 Issue: 6 Pages: 371-371
- DOI
  10.1093/jmicro/dfx035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07266
[Journal Article] Hexadecameric structure of an invertebrate gap junction channel2016
- Author(s)
  Oshima, A., Matsuzawa, T., Murata, K., Tani, K. and Fujiyoshi, Y.
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 428 Issue: 6 Pages: 1227-1236
- DOI
  10.1016/j.jmb.2016.02.011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26840019
[Journal Article] ギャップ結合チャネルの構造と多様性2016
- Author(s)
  大嶋篤典
- Journal Title
  
  膜
  
  Volume: 41 Pages: 50-56
- NAID
  130005249079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26840019
[Journal Article] Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.2016
- Author(s)
  A. Oshima, K. Tani and Y. Fujiyoshi
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13681-13681
- DOI
  10.1038/ncomms13681
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-16K07266
[Journal Article] GraDeR: membrane protein complex preparation for single particle cryo-EM.2015
- Author(s)
  Hauer F., Gerle C., Fischer N., Oshima A., Shinzawa-Itoh K., Shimada S., Yokoyama K., Fujiyoshi Y. & Stark H.
- Journal Title
  
  Structure
  
  Volume: 23 Issue: 9 Pages: 1769-1775
- DOI
  10.1016/j.str.2015.06.029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14464, KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-26650039, KAKENHI-PROJECT-26840019
[Journal Article] Oligomeric structure and functional characterization of C. elegans innexin-6 gap junction channels.2013
- Author(s)
  A. Oshima, T Matsuzawa, K. Nishikawa and Y. Fujiyoshi
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 15 Pages: 10513-10521
- DOI
  10.1074/jbc.m112.428383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22227004
[Journal Article] Oligomeric structure and functional characterization of C. elegans innexin-6 gap junction channels.2013
- Author(s)
  A. Oshima, T Matsuzawa, K. Nishikawa and Y. Fujiyoshi.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22227004
[Journal Article] Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.2011
- Author(s)
  A.Oshima
- Journal Title
  
  J.Mol.Biol.
  
  Volume: 405 Pages: 724-735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22227004
[Journal Article] Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels2011
- Author(s)
  A.Oshima, K.Tani, M.M.Toloue, Y.Hiroaki, A.Smock, S.Inukai, A.Cone, B.J.Nicholson, G.E.Snsinski, Y.Fujiyoshi
- Journal Title
  
  J.Mol.Biol.
  
  Volume: 405 Pages: 724-735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22227004
[Presentation] Structural insight into the closure of large pore channels in phospholipids by cryo-EM2023
- Author(s)
  Atsunori Oshima
- Organizer
  ION CHANNEL MODULATION SYMPOSIUM 2023-Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] Structures and gating of gap junction family proteins in phospholipids2023
- Author(s)
  Atsunori Oshima
- Organizer
  日本生理学学会第100回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Structures and gating of gap junction family proteins in phospholipids2023
- Author(s)
  Atsunori Oshima
- Organizer
  日本生理学学会第100回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] クライオ電子顕微鏡を用いた細胞間結合の構造研究の最前線2022
- Author(s)
  大嶋篤典
- Organizer
  第16回バイオ関連化学シンポジウム学生企画『Graduate Student Session』
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] クライオ電子顕微鏡とタンパク質構造生物学　糖鎖の可視化に向けて2022
- Author(s)
  大嶋篤典
- Organizer
  香川県希少糖戦略会議　第15回複合糖質・糖鎖部会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] Gating of gap junction family proteins involving phospholipids2022
- Author(s)
  Atsunori Oshima
- Organizer
  ISDD & KSSB JOINT SYMPOSIUM
- Invited
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] 脂質ナノディスクを利用したギャップ結合ファミリータンパク質の構造と膜透過機構2022
- Author(s)
  大嶋篤典
- Organizer
  生理研研究会「構造情報を基盤とした膜機能分子の生理機能理解に向けて」
- Invited
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Structures of gap junction family proteins in nanodiscs2022
- Author(s)
  Atsunori Oshima
- Organizer
  2022 Life Sciences International Symposium, R&E Center for Life Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Cryogenic electron microscopy (Cryo-EM)2022
- Author(s)
  Atsunori Oshima
- Organizer
  The 3rd Bioinformatics and Biodiversity Conference/ the 6th International Symposium on Bioinformatics (InSyB)/The 2nd Synthetic Biology and Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Structures of gap junction family proteins in nanodiscs,2022
- Author(s)
  Atsunori Oshima
- Organizer
  2022 Life Sciences International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] Cryogenic electron microscopy (Cryo-EM)2022
- Author(s)
  Atsunori Oshima
- Organizer
  The 3rd Bioinformatics and Biodiversity Conference/ the 6th International Symposium on Bioinformatics (InSyB)/The 2nd Synthetic Biology and Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] 脂質ナノディスクを利用したギャップ結合ファミリータンパク質の構造と膜透過機構2022
- Author(s)
  大嶋篤典
- Organizer
  生理研研究会「構造情報を基盤とした膜機能分子の生理機能理解に向けて」
- Invited
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] Structural Study of Actin-Aplyronine A-Tubulin Heterotrimeric Complex and　Development of Actin-affinity Tags2022
- Author(s)
  Didik H. Utomo, Akari Fujieda, Atsunori Oshima, Akihiro Narita, Momoko, Takahashi, Hideo Kigoshi, and Masaki Kita
- Organizer
  日本化学会102回春季年会
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] Structural Study of Actin-Aplyronine A-Tubulin Heterotrimeric Complex and Development of Actin-affinity Tags2022
- Author(s)
  Didik H. Utomo, Akari Fujieda, Atsunori Oshima, Akihiro Narita, Momoko Takahashi, Hideo Kigoshi, and Masaki Kita
- Organizer
  日本化学会102回春季年会
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Gating of gap junction family proteins involving phospholipids2022
- Author(s)
  Atsunori Oshima
- Organizer
  ISDD & KSSB JOINT SYMPOSIUM
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] クライオ電子顕微鏡を用いた細胞間結合の構造研究の最前線2022
- Author(s)
  大嶋篤典
- Organizer
  第16回バイオ関連化学シンポジウム学生企画『Graduate Student Session』
- Invited
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] クライオ電子顕微鏡とタンパク質構造生物学　糖鎖の可視化に向けて2022
- Author(s)
  大嶋篤典
- Organizer
  香川県希少糖戦略会議　第15回複合糖質・糖鎖部会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] クライオ電子顕微鏡の試料調製と構造研究2021
- Author(s)
  大嶋篤典
- Organizer
  量子構造生物学委員会の第3回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Structural biology of gap junction proteins2021
- Author(s)
  Atsunori Oshima
- Organizer
  Symposium on Computer Simulations and Cryo-ET/EM of Complex Biomolecular Systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Structural insights into the unique activation mechanism of the MrgD2021
- Author(s)
  鈴木翔大、飯田桃子、廣明洋子、川本晃大、加藤貴之、大嶋篤典
- Organizer
  第44回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Structural biology of gap junction proteins2021
- Author(s)
  Atsunori Oshima
- Organizer
  Symposium on Computer Simulations and Cryo-ET/EM of Complex Biomolecular Systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] ギャップ結合タンパク質のナノディスクにおける構造2021
- Author(s)
  Atsunori Oshima
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] ナノディスクに再構成したPanx1チャネルの構造変化2021
- Author(s)
  大嶋篤典、葛谷麻希、平野秀美、林田研一、渡邉正勝、小林一美、谷一寿、藤吉好則
- Organizer
  日本顕微鏡学会第77回学術講演会
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] クライオ電子顕微鏡を用いた細胞間結合チャネルの構造研究2021
- Author(s)
  大嶋篤典
- Organizer
  日本顕微鏡学会第77回学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] Structures of gap junction proteins in nanodiscs2021
- Author(s)
  Atsunori Oshima
- Organizer
  第59回生物物理学会年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] クライオ電子顕微鏡の試料調製と構造研究2021
- Author(s)
  大嶋篤典
- Organizer
  量子構造生物学委員会の第3回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] ナノディスクに再構成したPanx1チャネルの構造変化2021
- Author(s)
  大嶋篤典、葛谷麻希、平野秀美、林田研一、渡邉正勝、小林一美、谷一寿、藤吉好則
- Organizer
  顕微鏡学会第77回学術講演会
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Structural insights into the unique activation mechanism of the MrgD2021
- Author(s)
  鈴木翔大、飯田桃子、廣明洋子、川本晃大、加藤貴之、大嶋篤典
- Organizer
  第44回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19215
[Presentation] Structures of the Innexin-6 gap junction hemichannels in nanodiscs2020
- Author(s)
  Burendei, B, Shinozaki, R., Watanabe, M., Terada, T., Tani, K., Fujiyoshi, Y., Oshima, A.
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Cryo-EM structures of undocked innexin-6 hemichannels in lipid nanodiscs2019
- Author(s)
  Oshima, A.
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] Cryo-EM structures of undocked innexin-6 gap junction hemichannels2019
- Author(s)
  Burendei, B, Shinozaki, R., Watanabe, M., Terada, T., Tani, K., Fujiyoshi, Y., Oshima, A.
- Organizer
  International Gap Junction Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] 名古屋大学タンパク質生産領域の支援技術紹介2019
- Author(s)
  大嶋篤典
- Organizer
  AMED/BINDS　連携セミナー
- Data Source
  KAKENHI-PROJECT-19H03165
[Presentation] ギャップ結合チャネルのクライオ電子顕微鏡構造解析と試料調製2018
- Author(s)
  大嶋篤典
- Organizer
  日本顕微鏡学会　第74回学術講演会
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] クライオ電子顕微鏡用の試料調製とデータ収集2018
- Author(s)
  大嶋篤典
- Organizer
  PF研究会：X線とクライオ電子顕微鏡で挑む生命の機能とかたち
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] クライオ電子顕微鏡単粒子解析を利用した膜タンパク質複合体の構造研究2018
- Author(s)
  大嶋篤典
- Organizer
  日本薬学会大138回年回
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] 創薬を目指したクライオ電子顕微鏡による構造研究2018
- Author(s)
  大嶋篤典
- Organizer
  名古屋大学の卓越・先端・次世代シンポジウム「生命科学のフロントランナー」
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] 細胞間結合チャネルのクライオ電子顕微鏡法2018
- Author(s)
  大嶋篤典
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] クライオ電子顕微鏡を用いたギャップ結合チャネルの構造研究2018
- Author(s)
  大嶋篤典
- Organizer
  第79回応用物理学会秋季学術講演会
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] Cryo-EM structure of an innexin gap junction channel at atomic resolution2017
- Author(s)
  Oshima, A., Tani, K. and Fujiyoshi, Y.
- Organizer
  Janelia Conference “Electrical Synapses”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] クライオ電子顕微鏡法を用いたギャップ結合チャネルの構造研究2017
- Author(s)
  大嶋篤典
- Organizer
  生命科学系学会合同年次大会(ConBio2017)
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] クライオ電子顕微鏡を用いたINX-6ギャップ結合チャネルの原子分解能単粒子解析2017
- Author(s)
  大嶋篤典、谷一寿、藤吉好則
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] ギャップ結合チャネルの構造とcryo-EMサンプル調製法2017
- Author(s)
  大嶋篤典
- Organizer
  日本学術振興会構造生物169委員会　第52回研究会
- Place of Presentation
  東京大学山上会館
- Year and Date
  2017-03-06
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] Structure of the C. elegans innexin-6 Gap Junction Channel2017
- Author(s)
  Oshima, A., Tani, K. and Fujiyoshi, Y.
- Organizer
  Microscopy & Microanalysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] Single particle cryo-EM of a gap junction channel2017
- Author(s)
  大嶋篤典
- Organizer
  第55回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] クライオ電子顕微鏡によるInnexin-6ギャップ結合チャネルの原子分解能構造2016
- Author(s)
  大嶋篤典
- Organizer
  日本顕微鏡学会関西支部特別講演会
- Place of Presentation
  京都大学宇治キャンパスおうばくプラザ
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] ギャップ結合チャネルの多様な構造と機能2016
- Author(s)
  大嶋篤典
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  東北大学川内北キャンパス
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] THREE-DIMENSIONAL STRUCTURE OF INNEXIN GAP JUNCTION CHANNELS STUDIED BY ELECTRON CRYSTALLOGRAPHY2016
- Author(s)
  Atsunori Oshima, Tomohiro Matsuzawa, Kazuyoshi Murata, Kazutoshi Tani and Yoshinori Fujiyoshi
- Organizer
  60th Biophysical Society Annual Meeting
- Place of Presentation
  Los Angeles Convention Center, Los Angeles
- Year and Date
  2016-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] クライオ電子顕微鏡による膜タンパク質の高分解能単粒子解析2016
- Author(s)
  大嶋篤典
- Organizer
  第3回名古屋大学-ラクオリア創薬　創薬シンポジウム
- Place of Presentation
  名古屋大学鶴舞キャンパス　鶴友会館
- Year and Date
  2016-12-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K07266
[Presentation] Three dimensional structure of C. elegans innexin gap junction channels2015
- Author(s)
  Atsunori Oshima, Tomohiro Matsuzawa, Kazuyoshi Murata, Kazutoshi Tani and Yoshinori Fujiyoshi
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド、神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] Initial 3D reconstruction of innexin gap junction channels by electron crystallography2015
- Author(s)
  Atsunori Oshima,, Tomohiro Matsuzawa, Kazuyoshi Murata, Kazutoshi Tani and Yoshinori Fujiyoshi
- Organizer
  日本顕微鏡学会　第71回学術講演会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] Electron Microscopic Studies of Invertebrate Gap Junction Channels
- Author(s)
  Atsunori Oshima, Tomohiro Matsuzawa, Kazuyoshi Murata, Kouki Nishikawa, Kazutoshi Tani and Yoshinori Fujiyoshi,
- Organizer
  IGER International Symposium on Frontiers in Biological Research with Advanced Electron Microscope Technologies
- Place of Presentation
  Nagoya University
- Year and Date
  2015-01-15 – 2015-01-16
- Invited
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] Structure and diversity of gap junction channels studied by electron microscopy
- Author(s)
  Atsunori Oshima
- Organizer
  第120回日本解剖学会総会・全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-21 – 2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] Oligomeric form and function of C. elegans innexin-6 gap junction channels
- Author(s)
  Atsunori Oshima, Tomohiro Matsuzawa, Kazuyoshi Murata, Kouki Nishikawa, and Yoshinori Fujiyoshi
- Organizer
  the 23rd International Union of Crystallography (IUCr) Congress and General Assembly
- Place of Presentation
  Montréal, Québec, Canada
- Year and Date
  2014-08-05 – 2014-08-12
- Invited
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] Electron microscopy of C. elegans innexin-6 gap junction channels indicates the characteristic subunit organization
- Author(s)
  Atsunori Oshima, Tomohiro Matsuzawa, Kazuyoshi Murata, Kouki Nishikawa, and Yoshinori Fujiyoshi
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] 電子顕微鏡で見るギャップ結合チャネルの構造と多様性
- Author(s)
  大嶋篤典
- Organizer
  「電子顕微鏡機能イメージングの医学・生物学への応用」～次世代の生物電顕を考える～
- Place of Presentation
  生理学研究所
- Year and Date
  2014-11-12 – 2014-11-13
- Invited
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] 電子顕微鏡によるイネキシンギャップ結合チャネルの構造研究
- Author(s)
  大嶋篤典、松澤朋寛、村田和義、西川幸希、藤吉好則
- Organizer
  日本顕微鏡学会第70回記念学術講演会
- Place of Presentation
  幕張メッセ国際会議場
- Year and Date
  2014-05-11 – 2014-05-13
- Data Source
  KAKENHI-PROJECT-26840019
[Presentation] Initial 3D reconstruction of innexin gap junction channels by electron crystallography
- Author(s)
  Atsunori Oshima,, Tomohiro Matsuzawa, Kazuyoshi Murata, Kazutoshi Tani and Yoshinori Fujiyoshi
- Organizer
  日本顕微鏡学会　第71回学術講演会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2015-05-13 – 2015-05-15
- Data Source
  KAKENHI-PROJECT-26840019

1. FUJIYOSHI Yoshinori (80142298)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. ABE Kazuhiro (60596188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 谷一寿 (20541204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 入江克雅 (20415087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田中康太郎 (70916668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NUMOTO Nobutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. NISHIZAWA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. Gerle Christoph

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 亀川亜希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 渡邉正勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oshima Atsunori 大嶋 篤典

OHSHIMA Atsunori 大嶋 篤典

Research Projects

Research Products

Co-Researchers

Membrane permeation mechanism mediated by large pore channels contributed by phospholipidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel gating model for a large pore channel in a lipid bilayerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cryo-EM analysis of intercellular junction channels of higher animalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

High-resolution single particle analysis of intercellular channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies in structural physiology of channels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural and functional analysis of gap junction channels using electron microscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural and functional study of membrane proteins based on electron crystallography

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Structures and Gating Mechanism of Large Pore Channels2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure and function of H+/K+ pump mutants reveal Na+/K+ pump mechanisms2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution2022

Oshima Atsunori 大嶋篤典

OHSHIMA Atsunori 大嶋篤典