nishimura junichi 西村純一

… Alternative Names

NISHIMURA Jun-ichi 西村純一

NISHIMURA Jun-Ichi 西村純一

Less

Researcher Number	80464246
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 招へい教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院医学系研究科, 招へい教授 2020 – 2021: 大阪大学, 医学系研究科, 招へい教授 2016 – 2019: 大阪大学, 医学系研究科, 助教 2016: 大阪大学, 医学部, 助教 2014 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2009 – 2010: Osaka University, 医学系研究科, 助教 2008: Osaka University, 医学系研究科, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator 発作性夜間ヘモグロビン尿症 / 溶血 / 補体 / クロ－ン性拡大 / 造血幹細胞 / クローン性拡大 / PNHクローン / PIGA遺伝子 / 遺伝子多型 / エクリズマブ … More / 発作性夜間血色素尿症 / 血管外溶血 / オプソニン化 / C3b / SELEX / RNAアプタマー / 発作性夜間ヘモグロビン尿症(PNH) … More Except Principal Investigator PNH / 発作性夜間ヘモグロビン尿症 / 補体 / 抗補体薬 / 血管外溶血 / 血管内溶血 / 溶血性貧血 / 寒冷凝集素 / 補体関連疾患 / 自己免疫性溶血性貧血 / CAD / 古典経路 / 寒冷凝集素症 / 系統樹 / 遺伝学的系統樹解析 / 全ゲノム解析 / 血液疾患 / 補体疾患 / プロペルジン / ゲノム / 次世代シーケンサー / 遺伝学 / 内科 / 次世代シークエンサー / 遺伝子解析 / bone marrow failure / 骨髄不全症 / 血液 / ビタミンB1 / GPI / ビタミンB6 / PIGA / clonal expansion / GPI アンカー / ビタミンB６ / ビタミンB１ / アルカリホスファターゼ / 遺伝子多型 Less

Unraveling the mechanism of poor response to anti-comlement drug in cold agglutinin disease treatment
- Principal Investigator
  
  植田康敬
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Osaka University
PNHクローンの起源と変遷
- Principal Investigator
  
  高森弘之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  The University of Tokyo
Identification of the most appropriate therapeutic target for PNH
- Principal Investigator
  
  Ueda Yasutaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Osaka University
Analysis for hematopoietic dynamics of clonal expansion in PNHPrincipal Investigator
- Principal Investigator
  
  西村純一
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Osaka University
Elucidation of mechanism of pathogenesis of paroxysmal nocturnal hemoglobinuria
- Principal Investigator
  
  Takamori Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Exhaustive analysis for clinical application of anti-complement drugs
- Principal Investigator
  
  Ueda Yasutaka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Analysos of metabolic abnormality which causes clonal expansion in Paroxysmal nocturnal hemoglobinuria
- Principal Investigator
  
  Murakami Yoshiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Investigation of eculizumab therapeutic response to patients with PNHPrincipal Investigator
- Principal Investigator
  
  NISHIMURA Jun-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Development of target therapeutic for PNH using RNA aptamerPrincipal Investigator
- Principal Investigator
  
  NISHIMURA Jun-Ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2011 2010 2009 2008

All Journal Article Presentation Book

[Book] 内科学第11版2017
- Author(s)
  西村純一
- Total Pages
  2385
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-26461447
[Book] 貧血学2017
- Author(s)
  西村純一
- Total Pages
  644
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26461447
[Book] Paroxysmal Nocturnal Hemoglobinuria From Bench to Bedside2017
- Author(s)
  Nakakuma H, Shichishima T, Nishimura J
- Total Pages
  358
- Publisher
  springer
- Data Source
  KAKENHI-PROJECT-26461447
[Book] Paroxysmal Nocturnal Hemoglobinuria From Bench to Bedside2017
- Author(s)
  Nishimura J, Kinoshita T, Kanakura Y
- Total Pages
  358
- Publisher
  springer
- Data Source
  KAKENHI-PROJECT-26461447
[Book] EBM 血液疾患の治療 2017-20182016
- Author(s)
  西村純一
- Total Pages
  549
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26461447
[Book] 中山書店2015
- Author(s)
  植田　康敬、西村　純一　（金倉　譲編）
- Total Pages
  560
- Publisher
  最新ガイドライン準拠　血液疾患　診断・治療指針
- Data Source
  KAKENHI-PROJECT-15K09502
[Book] ブラッシュアップ骨髄不全症（松田晃編）2015
- Author(s)
  西村純一、植田康敬
- Total Pages
  193
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26461447
[Book] 今日の治療指針2015
- Author(s)
  西村純一
- Total Pages
  1973
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-26461447
[Book] Principles and Practice 血液・造血器・リンパ系（千葉滋編）2015
- Author(s)
  西村純一
- Total Pages
  385
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-26461447
[Book] 私の論文が『NEJM』に載ったときの話（北村聖編）2015
- Author(s)
  西村純一
- Total Pages
  81
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-26461447
[Book] ブラッシュアップ骨髄不全2015
- Author(s)
  植田　康敬、西村　純一　（松田　晃編）
- Total Pages
  193
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09502
[Book] 発作性夜間ヘモグロビン尿症（PNH）～遺伝子異常の解析から新規治療薬の臨床・開発まで～（金倉譲、西村純一編）2015
- Author(s)
  植田康敬、西村純一
- Total Pages
  239
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-26461447
[Book] Annual Review 血液 20152015
- Author(s)
  西村純一
- Total Pages
  286
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26461447
[Book] 発作性夜間ヘモグロビン尿症（ＰＮＨ）2015
- Author(s)
  植田　康敬、西村　純一　（金倉　譲編）
- Total Pages
  239
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-15K09502
[Book] 臨床血液内科マニュアル2014
- Author(s)
  江副幸子、西村純一
- Total Pages
  372
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-26461447
[Book] 新戦略による貧血治療2014
- Author(s)
  西村純一
- Total Pages
  287
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-26461447
[Book] Annual Review血液20112011
- Author(s)
  植田康敬、西村純一
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20591123
[Book] 今日の治療指針2011年版2011
- Author(s)
  西村純一
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20591123
[Book] Annual Review血液20112011
- Author(s)
  西村純一
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20591123
[Book] 2011今日の治療指針2011
- Author(s)
  西村純一
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20591123
[Book] 血液疾患最新の治療2011-20132010
- Author(s)
  西村純一、金倉譲
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-20591123
[Book] 血液疾患最新の治療 2011-20132010
- Author(s)
  西村純一、金倉譲
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-20591123
[Book] ステロイドの使い分け2010
- Author(s)
  西村純一、柴山浩彦、水木満佐央、金倉譲
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20591123
[Book] 講義録血液・造血器疾患学 (小澤敬也、直江知樹、坂田洋一編)2008
- Author(s)
  西村純一
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-20591123
[Book] 講義録血液・造血器疾患学2008
- Author(s)
  西村純一、金倉譲
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] A longitudinal analysis of paroxysmal nocturnal haemoglobinuria‐type cells in patients with bone marrow failure: Results of a prospective multi‐centre study in Japan2023
- Author(s)
  Ishiyama Ken、Yonemura Yuji、Kawaguchi Tatsuya、Hosokawa Kohei、Sugimori Chiharu、Ueda Yasutaka、Takamori Hiroyuki、Obara Naoshi、Noji Hideyoshi、Shirasugi Yukari、Ando Kiyoshi、Shichishima Tsutomu、Ninomiya Haruhiko、Chiba Shigeru、Nishimura Jun‐ichi、Kanakura Yuzuru、Nakao Shinji
- Journal Title
  
  British Journal of Haematology
  
  Volume: 203 Issue: 3 Pages: 468-476
- DOI
  10.1111/bjh.19048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07859, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K08367
[Journal Article] Mitigating Drug Target Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors2023
- Author(s)
  Nishimura Jun‐ichi、Soubret Antoine、Arase Noriko、et al.
- Journal Title
  
  Clinical Pharmacology & Therapeutics
  
  Volume: 113 Issue: 4 Pages: 904-915
- DOI
  10.1002/cpt.2851
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08344, KAKENHI-PROJECT-18K08296, KAKENHI-PROJECT-23K07859
[Journal Article] Long-term follow-up of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab: post-marketing surveillance in Japan2022
- Author(s)
  Ikezoe Takayuki、Noji Hideyoshi、Ueda Yasutaka、Kanda Yoshinobu、Okamoto Shinichiro、Usuki Kensuke、Matsuda Takahisa、Akiyama Hirozumi、Shimono Akihiko、Yonemura Yuji、Kawaguchi Tatsuya、Chiba Shigeru、Kanakura Yuzuru、Nishimura Jun-Ichi、Ninomiya Haruhiko、Obara Naoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 4 Pages: 470-480
- DOI
  10.1007/s12185-022-03287-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08862, KAKENHI-PROJECT-21K08365
[Journal Article] Pegcetacoplan versus Eculizumab in PNH2021
- Author(s)
  Yasutaka Ueda, Hiroyuki Takamori, Jun-Ichi Nishimura
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 385 Issue: 18 Pages: 1723-1726
- DOI
  10.1056/nejmc2106424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08862
[Journal Article] The Complement C5 Inhibitor Crovalimab in Paroxysmal Nocturnal Hemoglobinuria2020
- Author(s)
  Roth A, Nishimura JI, Nagy Z, Gaa;l-Weisinger J, Panse J, Yoon SS, Egyed M, Ichikawa S, Ito Y, Kim JS, Ninomiya H, Schrezenmeier H, Sica S, Usuki K, Sicre de Fontbrune F, Soret J, Sostelly A, Higginson J, Dieckmann A, Gentile B, et al.
- Journal Title
  
  Blood
  
  Volume: 135 Issue: 12 Pages: 912-920
- DOI
  10.1182/blood.2019003399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Journal Article] Successful Treatment of a PNH Patient Non-Responsive to Eculizumab With the Novel Complement C5 Inhibitor Coversin (Nomacopan)2020
- Author(s)
  Schols S, Nunn MA, Mackie I, Weston-Davies W, Nishimura JI, Kanakura Y, Blijlevens N, Muus P, Langemeijer S.
- Journal Title
  
  Br J Haematol
  
  Volume: 188 Issue: 2 Pages: 334-337
- DOI
  10.1111/bjh.16305
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Journal Article] Donor stem cell‐derived paroxysmal nocturnal hemoglobinuria after umbilical cord blood transplantation2020
- Author(s)
  Nakaya Yosuke、Nakao Takafumi、Ueda Yasutaka、Takamori Hiroyuki、Nishimura Jun‐Ichi、Tatsumi Naoko、Tsutsumi Minako、Yoshida Masahiro、Yoshimura Takuro、Hayashi Yoshiki、Yamane Takahisa
- Journal Title
  
  European Journal of Haematology
  
  Volume: 105 Issue: 5 Pages: 659-661
- DOI
  10.1111/ejh.13498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08862
[Journal Article] Complement and inflammasome overactivation mediates paroxysmal nocturnal hemoglobinuria with autoinflammation.2019
- Author(s)
  Hochsmann B, Murakami Y, Osato M, Knaus A, Kawamoto M, Inoue N, Hirata T, Murata S, Anliker M, Eggermann T, Jager M, Floettmann R, Hollein A, Murase S, Ueda Y, Nishimura JI, Kanakura Y, Kohara N, Schrezenmeier H, Krawitz PM, Kinoshita T.
- Journal Title
  
  The Journal of Clinical Investigation
  
  Volume: 129 Issue: 12 Pages: 5123-5136
- DOI
  10.1172/jci123501
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08862, KAKENHI-PROJECT-16H04753, KAKENHI-PROJECT-19H03529, KAKENHI-PROJECT-19K08864, KAKENHI-PROJECT-18K16097, KAKENHI-PLANNED-17H06422
[Journal Article] Comparative Study on Baseline Clinical Characteristics of Asian Versus non-Asian Patients With Paroxysmal Nocturnal Hemoglobinuria2019
- Author(s)
  Sakurai M, Jang JH, Chou WC, Kim JS, Wilson A, Nishimura JI, Chiou TJ, Kanakura Y, Lee JW, Okamoto S.
- Journal Title
  
  Int J Hematol
  
  Volume: 110 Issue: 4 Pages: 411-418
- DOI
  10.1007/s12185-019-02699-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Journal Article] Effects of eculizumab treatment on quality of life in patients with paroxysmal nocturnal hemoglobinuria in Japan2018
- Author(s)
  Y. Ueda, N. Obara, Y. Yonemura, H. Noji, M. Masuko, Y. Seki, K. Wada, T. Matsuda, H. Akiyama, T. Ikezoe, S. Chiba, Y. Kanda, T. Kawaguchi, T. Shichishima, H. Nakakuma, S. Okamoto, J. Nishimura, Y. Kanakura, H. Ninomiya
- Journal Title
  
  International Journal of Hematology
  
  Volume: epub Issue: 6 Pages: 1-10
- DOI
  10.1007/s12185-018-2409-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09502, KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09898
[Journal Article] PNH診療の参照ガイド改訂の要旨2017
- Author(s)
  植田　康敬, 西村　純一
- Journal Title
  
  PNHフロンティア
  
  Volume: 4 Pages: 36-42
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] 発作性夜間ヘモグロビン尿症（PNH)に対する抗補体薬療法の現状と展望2017
- Author(s)
  高森　弘之、植田　康敬、西村　純一
- Journal Title
  
  血液フロンティア
  
  Volume: 27(2) Pages: 77-84
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] 発作性夜間ヘモグロビン尿症2017
- Author(s)
  高森　弘之、植田　康敬、西村　純一
- Journal Title
  
  最新医学別冊
  
  Volume: n/a Pages: 116-128
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] 発作性夜間ヘモグロビン尿症（PNH）に対する抗補体薬療法の現状と展望2017
- Author(s)
  高森　弘之、植田　康敬、西村　純一
- Journal Title
  
  血液フロンティア
  
  Volume: 27 Pages: 77-84
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] 発作性夜間ヘモグロビン尿症（PNH）に対する抗補体薬療法の現状と展望2017
- Author(s)
  高森弘之、植田康敬、西村純一
- Journal Title
  
  血液フロンティア
  
  Volume: 27 Pages: 77-84
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] PNHの診断と治療の最前線2016
- Author(s)
  高森弘之、植田康敬、西村純一
- Journal Title
  
  血液内科
  
  Volume: 73 Pages: 208-214
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 発作性夜間ヘモグロビン尿症の診断と治療2016
- Author(s)
  植田　康敬、西村　純一
- Journal Title
  
  Medical Practice
  
  Volume: 33(9) Pages: 1419-1421
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] PNHのエクリズマブ療法における問題点　不応例と血管外溶血2016
- Author(s)
  植田　康敬、西村　純一
- Journal Title
  
  血液フロンティア
  
  Volume: 26(6) Pages: 39-46
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] 三位一体（医療・行政・患者）で進める難病問題 -さきがけとしてのPNH-2016
- Author(s)
  川口辰哉、金倉譲、西村純一、二宮治彦、橋本岳、福山哲郎、前田彰久、河陽輝、関つたえ、村上早代子
- Journal Title
  
  PNH Frontier
  
  Volume: 3 Pages: 6-17
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan.2016
- Author(s)
  Ninomiya H, Obara N, Chiba S, Usuki K, Nishiwaki K, Matsumura I, Shichishima T, Okamoto S, Nishimura JI, Ohyashiki K, Nakao S, Ando K, Kanda Y, Kawaguchi T, Nakakuma H, Harada D, Akiyama H, Kinoshita T, Ozawa K, Omine M, Kanakura Y.
- Journal Title
  
  Int J Hematol
  
  Volume: 104 Pages: 548-558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] Two consecutive pregnancies in a patient with paroxysmal nocturnal haemoglobinuria treated with anticoagulant therapy at different doses.2016
- Author(s)
  Sasano T, Matsumura I, Kimura T ,et al.
- Journal Title
  
  Blood Coagul Fibrinolysis.
  
  Volume: 27 Issue: 1 Pages: 109-112
- DOI
  10.1097/mbc.0000000000000386
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09461, KAKENHI-PROJECT-26461447, KAKENHI-PROJECT-26462506
[Journal Article] Pregnancy outcomes of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab: a Japanese experience and updated review.2016
- Author(s)
  Miyasaka N, Miura O, Kawaguchi T, Arima N, Morishita E, Usuki K, Morita Y, Nishiwaki K, Ninomiya H, Gotoh A, Imashuku S, Urabe A, Shichishima T, Nishimura JI, Kanakura Y.
- Journal Title
  
  Int J Hematol.
  
  Volume: Epub ahead of print
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 発作性夜間ヘモグロビン尿症（PNH：paroxysmal nocturnal hemoglobinuria）：最近の話題2016
- Author(s)
  西村純一
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 17 Pages: 380-387
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] PNHのエクリズマブ療法における問題点：不応例と血管外溶血2016
- Author(s)
  植田康敬、西村純一
- Journal Title
  
  血液フロンティア
  
  Volume: 26 Pages: 39-46
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] PNH診療の参照ガイド2016
- Author(s)
  西村純一、金倉譲
- Journal Title
  
  血液フロンティア
  
  Volume: 26 Pages: 21-28
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 発作性夜間血色素尿症（PNH）の補体がかかわる最新の話題と抗補体療法の未来2016
- Author(s)
  西村純一
- Journal Title
  
  医学のあゆみ
  
  Volume: 257 Pages: 827-831
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] PNHの診断と治療の最前線2016
- Author(s)
  高森　弘之、植田　康敬、西村　純一
- Journal Title
  
  血液内科
  
  Volume: 73(2) Pages: 208-214
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] PNHにおけるエクリズマブ反応性2015
- Author(s)
  西村純一
- Journal Title
  
  血液内科
  
  Volume: 70 Pages: 229-234
- NAID
  40020385210
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] The C5 gene polymorphism in patients with PNH2015
- Author(s)
  Nishimura J, Kanakura Y.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 2 Pages: 103-110
- DOI
  10.11406/rinketsu.56.103
- NAID
  130004920719
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 「PNH診療の参照ガイド」改訂のポイント　1.重症度分類2015
- Author(s)
  西村純一
- Journal Title
  
  PNH Frontier
  
  Volume: 2 Pages: 30-35
- Open Access
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] C5遺伝子多型と発作性夜間血色素尿症（PNH）治療薬エクリズマブに対する反応不良.2015
- Author(s)
  西村純一
- Journal Title
  
  最新醫学
  
  Volume: 70 Pages: 1716-1721
- NAID
  40020559265
- Open Access
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 発作性夜間血色素尿症：病態と治療の最前線.2015
- Author(s)
  植田康敬、西村純一
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 104 Pages: 1397-1404
- Open Access
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 発作性夜間ヘモグロビン尿症は補体に対する抗体さえ投与しておけばもう安心？2015
- Author(s)
  西村純一
- Journal Title
  
  内科
  
  Volume: 116 Pages: 1041-1045
- Open Access
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 特集：貧血：基礎知識から治療の最前線まで　発作性夜間血色素尿症：病態と治療の最前線2015
- Author(s)
  植田　康敬、西村　純一
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 104(7) Pages: 1397-1404
- Data Source
  KAKENHI-PROJECT-15K09502
[Journal Article] C５の遺伝子多様体とエクリズマブに対する反応不良2014
- Author(s)
  西村純一
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 44 Pages: 273-276
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 『難治性貧血の診療ガイド』「PNHの診断基準と診療の参照ガイド」改訂の要旨2014
- Author(s)
  西村純一
- Journal Title
  
  PNH Frontier
  
  Volume: 1 Pages: 30-35
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] 発作性夜間ヘモグロビン尿症の診断と病態・治療の進歩2014
- Author(s)
  西村純一
- Journal Title
  
  最新醫学
  
  Volume: 69 Pages: 2096-2102
- Data Source
  KAKENHI-PROJECT-26461447
[Journal Article] Safety and efficacy of the terminal complement Inhibitor Eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria : The AEGIS clinical trial.2011
- Author(s)
  金倉譲(1番目), 西村純一(10番目), 他14名
- Journal Title
  
  Int J Hematol 93
  
  Pages: 36-46
- NAID
  10029532438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間ヘモグロビン尿症2011
- Author(s)
  西村純一
- Journal Title
  
  Medicament News 2046
  
  Pages: 6-7
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria : the AEGIS clinical trial.2011
- Author(s)
  Kanakura Y, Nishimura J, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Pages: 36-46
- NAID
  10029532438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間血色素尿症に対するエクリズマブ療法2010
- Author(s)
  西村純一
- Journal Title
  
  血液フロンティア
  
  Volume: 20 Pages: 41-47
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間血色素尿症に対するエクリズマブ療法2010
- Author(s)
  西村純一
- Journal Title
  
  血液フロンティア 20
  
  Pages: 41-47
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間ヘモグロビン尿症の病態と治療2010
- Author(s)
  西村純一、金倉譲
- Journal Title
  
  日本医事新報
  
  Volume: 4520 Pages: 45-49
- NAID
  40017391894
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間ヘモグロビン尿症の病態と治療2010
- Author(s)
  西村純一, 金倉譲
- Journal Title
  
  日本医事新報 4520
  
  Pages: 45-49
- NAID
  40017391894
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 血液病とQOL-溶血性貧血とQOL2009
- Author(s)
  西村純一
- Journal Title
  
  血液フロンティア 13
  
  Pages: 11-18
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間ヘモグロビン尿症の治療について2009
- Author(s)
  西村純一
- Journal Title
  
  再生つばさの会 67
  
  Pages: 1-2
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 溶血性貧血とQOL2009
- Author(s)
  西村純一
- Journal Title
  
  血液フロンティア 13
  
  Pages: 11-18
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間血色素尿症の新規治療薬2008
- Author(s)
  西村純一, 弘田稔幸
- Journal Title
  
  総合臨床 57
  
  Pages: 643-646
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] RNA研究の新知見と医療応用への展望米国におけるRNAアプタマーによる創薬の現状2008
- Author(s)
  西村純一
- Journal Title
  
  実験医学 2008年6月増刊号 26
  
  Pages: 199-204
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 貧血一最新の基礎と臨床一基礎編貧血の分子病態一各論一発作性夜間ヘモグロビン尿症(PNH)2008
- Author(s)
  西村純一
- Journal Title
  
  日本臨床 66
  
  Pages: 490-496
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間ヘモグロビン尿症(PNH)2008
- Author(s)
  西村純一, 金倉譲
- Journal Title
  
  日本臨床 66
  
  Pages: 490-496
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 発作性夜間血色素尿症の治療2008
- Author(s)
  西村純一, 金倉譲
- Journal Title
  
  Mebio 25
  
  Pages: 37-43
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 臨床血液学一新たなエヴィデンスの実践に向けてトピックス発作性夜間血色素尿症の新規治療薬2008
- Author(s)
  西村純一
- Journal Title
  
  総合臨床 57
  
  Pages: 643-646
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 造血器疾患治療の新しい潮流発作性夜間血色素尿症の治療2008
- Author(s)
  西村純一
- Journal Title
  
  Mebio 25
  
  Pages: 37-43
- Data Source
  KAKENHI-PROJECT-20591123
[Journal Article] 米国におけるRNAアプタマーによる創薬の現状2008
- Author(s)
  西村純一
- Journal Title
  
  実験医学 26
  
  Pages: 199-204
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] nsights from Trajectories of PIGA-Mutated Clones in Paroxysmal Nocturnal Hemoglobinuria2023
- Author(s)
  Yasutaka Ueda, Jun-ichi Nishimura, Naoki Hosen et al
- Organizer
  The 65th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07859
[Presentation] Clinical Significance of Small PNH-Type Cell Populations in Bone Marrow Failure Syndromes - an Interim Analysis of Japanese Multicentrer Prospective Study -2021
- Author(s)
  Yasutaka Ueda, Kohei Hosokawa, Ken Ishiyama, Hiroyuki Takamori, Yuji Yonemura, Naoshi Obara, Hideyoshi Noji, Kiyoshi Ando, Tsutomu Shichishima, Takayuki Ikezoe, Shigeru Chiba, Haruhiko Ninomiya, Tatsuya Kawaguchi , Jun-ichi Nishimura , Yuzuru Kanakura and Shinji Nakao
- Organizer
  63rd American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08862
[Presentation] An Optimized Crovalimab Dose and Regimen Reduced the Formation of Drug-Target-Drug Complexes in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Phase I/II COMPOSER Trial2020
- Author(s)
  Nishimura J, Soubret A, Buatois S, Charoin JE, Sreckovic S, Bucher C, Hernandez-Sanchez J,Jordan G, Ramos J, Arase N,Hotta M, Isaka Y, Ito Y, Kanakura Y, Kim JS, Kinoshita T, Morii E, Panse J, De Latour RP, Roth A, Schrezenmeier H, Sica S, Takamori H, Ueda Y et al
- Organizer
  62nd American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08862
[Presentation] The Relationship Between the Pretreatment PNH Clone Size and Clinical Course in Patients with Bone Marrow Failure Syndromes: Interim Analysis of Japanese Multicenter Prospective Study2019
- Author(s)
  Ueda Y, Hosokawa K, Ishiyama K, Takamori H, Yonemura Y, Obara N, Noji H, Takahashi H, Shirasugi Y, Matsuda T, Ando K, Shichishima T, Ikezoe T, Chiba S, Ninomiya H, Kawaguchi T, Nishimura J, Kanakura Y, Nakao S
- Organizer
  24th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Presentation] Terminal complement inhibitors: Anti-C5: SKY592019
- Author(s)
  Nishimura J, Roth A
- Organizer
  The New Era of Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria: In memory of our friend Bruno Rotoli
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Presentation] Breakthrough Hemolysis in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Ravulizumab: Results of a 52-Week Extension from Two Phase 3 Studies2019
- Author(s)
  Hill A, Piatek CI, de Latour RP, Wong LLL, Wells RA, Brodsky RA, Kim JS, Nishimura J, Kuriakose P, Pavani R, Liu P, Ortiz S, Schrezenmeier H, Lee JW, Kulasekararaj A
- Organizer
  The American Society of Hematology 61st Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Presentation] Characterizing C5 Inhibition with the SMART-Ig Anti-hC5 Antibody Crovalimab in PNH Patients Using Free Available Paratopes2019
- Author(s)
  Sostelly A, Soubret A, Bucher C, Buatois S, Charoin JE, Jordan G, Klughammer B, Dieckmann A, Fukuzawa T, Gotanda K, Shinomiya K, Yoon SS, Panse JP, Nishimura J, Roth A, Nagy Z, de Latour RP
- Organizer
  The American Society of Hematology 61st Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Presentation] Long Term Follow-Up of PNH Patients Treated with the Smart Anti-hC5 Antibody (SKY59/Ro7112689) in the Open Label Extension (OLE) of the Composer Trial2019
- Author(s)
  Roth A, Nagy Z, de Latour RP, Ninomya H, Panse J, Yoon SS, Egyed M, Ichikawa S, Ito Y, Kim JS, Schrezenmeier H, Sica S, Usuki K, Sostelly A, Higginson J, Dieckmann A, Anzures-Cabreras J, Shinomiya K, Klughammer B, Jahreis A, Bucher C, Nishimura J
- Organizer
  24th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Presentation] THE RELATIONSHIP BETWEEN THE PRETREATMENT PNH CLONE SIZE AND CLINICAL COURSE IN PATIENTS WITH BONE MARROW FAILURE SYNDROMES: INTERIM ANALYSIS OF JAPANESE MULTICENTER PROSPECTIVE STUDY2019
- Author(s)
  Yasutaka Ueda, Kohei Hosokawa, Ken Ishiyama, Hiroyuki Takamori, Yuji Yonemura, Naoshi Obara, Hideyoshi Noji, Hiroshi Takahashi, Yukari Shirasugi, Takahisa Matsuda, Kiyoshi Ando, Tsutomu Shichishima, Takayuki Ikezoe, Shigeru Chiba, Haruhiko Ninomiya, Tatsuya Kawaguchi, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao
- Organizer
  24th Congress of European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08862
[Presentation] Exposure-Response Relationship of the SMART-Ig Anti-hC5 Antibody Crovalimab (SKY59): Results from the Umbrella Phase 1/2 Composer Trial in Healthy Volunteers and PNH Patients2019
- Author(s)
  Sostelly A, Buatois S, Soubret A, Winter E, Klughammer B, Hsu JC, Jordan G, Bucher C, CharoinJE, Gotanda K, Shinomiya K, Nagy Z, Panse JP, Yoon SS, de Latour RP, Nishimura J, Roth A
- Organizer
  The American Society of Hematology 61st Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08864
[Presentation] Current Status and Optimal Management of Eculizumab Poor-Responders Due to C5 Polymorphisms2018
- Author(s)
  Yasutaka Ueda, Hiroyuki Takamori, Jun-Ho Jang, Chezi Ganzel, Saskia Langemeijer, Makiko Osato, Petra Muus, Jong-Wook Lee, Jun-Ichi Nishimura and Yuzuru Kanakura
- Organizer
  ASH－60th American Society of Hematology Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09904
[Presentation] 抗補体薬C5治療下のPNH患者における尿中ヘモジデリン検出の有用性2018
- Author(s)
  植田　康敬、堀田　真希、小林　渉、高森　弘之、西村　純一、日高　洋、金倉　譲
- Organizer
  第80回　日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09904
[Presentation] An optimal management of PNH patients on anti-C5 antibody2018
- Author(s)
  Hiroyuki Takamori, Yasutaka Ueda, Makiko Osato, Satoru Hayashi, Junichi Nishimura, Yuzuru Kanakura
- Organizer
  第80回　日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09904
[Presentation] 遺伝子多型と抗体医薬の反応性2017
- Author(s)
  高森　弘之、植田　康敬、大里　真幸子、西村　純一、金倉　譲
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] 発作性夜間ヘモグロビン尿症の治療におけるエクリズマブ時代の新たな課題2017
- Author(s)
  植田　康敬、高森　弘之、大里　真幸子、西村　純一、金倉　譲
- Organizer
  第54回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] Elucidation of Autoinflammatory Mechanism in Pigt-PNH2017
- Author(s)
  Makiko Osato, Yoshiko Murakami, Shogo Murata, Jun-Ichi Nishimura, Yasutaka Ueda, Taroh Kinoshita, Yuzuru Kanakura
- Organizer
  The American Society of Hematology 59th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] Baseline Assessment of Patients with Newly-Diagnosed Acquired Bone Marrow Failure Enrolled in a Prospective Observational Study, “Search for Unidentified Links between PNH Clone Size and the Related Clinical Manifestations By High Precision Flow Cytometry (SUPREMACY)”2017
- Author(s)
  Yuji Yonemura, Tatsuya Kawaguchi, Ken Ishiyama, Chiharu Sugimori, Kohei Hosokawa, Naoshi Obara, Hideyoshi Noji, Yukari Shirasugi, Yasutaka Ueda, Hiroyuki Takamori, Tsutomu Shichishima, Shigeru Chiba, Haruhiko Ninomiya, Kiyoshi Ando, Jun-Ichi Nishimura, Yuzuru Kanakura, Masanori Takahashi, Shinji Nakao
- Organizer
  The American Society of Hematology 59th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] Emerging issues in the era of eculizumab treatment with PNH: an institutional experience and review2016
- Author(s)
  高森弘之、植田康敬、大里真幸子、林悟、西村純一、金倉譲
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] The First Follow-up Data Analysis of Patients with Acquired Bone Marrow Failure Harboring a Small Population of PNH-Type Cells in the Japanese, Multicenter, Prospective Study Optima2016
- Author(s)
  Ueda Y, Nishimura J, Sugimori C, Hosokawa K, Yonemura Y, Obara1 N, Noji H, Nakamura Y, Shirasugi Y, Ando K, Shichishima T, Ninomiya H, Chiba1 S, Kawaguchi T, Kanakura Y, Nakao S
- Organizer
  The American Society of Hematology 58th Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] A CLINICAL SIGNIFICANCE AND TIME-DEPENDENT CHANGE OF PNH CLONE SIZE IN PATIENTS WITH BONE BARROW FAILURE SYNDROME: JAPANESE MULTI-CENTRE PROSPECTIVE STUDY2016
- Author(s)
  Shirasugi Y, Sugimori C, Noji H, Shichishima T,Obara N, Chiba S, Ninomiya H, Nakamura Y, Ando K, Yonemura Y, Kawaguchi , Hosokawa K, Ueda Y, Nishimura J, Kanakura Y, Nakao S
- Organizer
  21st Congress of the European Hematology Association
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2016-06-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] Paroxysmal Nocturnal Hemoglobinuria Caused By Pigt Mutations; Atypical PNH2016
- Author(s)
  Murakami Y, Kwamoto M, Inoue N, Osato M, Murata S, Murase S, Yoshimura H, Ueda Y, Nishimura J, Kankura Y, Kohara N, Kinoshita T
- Organizer
  The American Society of Hematology 58th Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] 骨髄不全症の病態解析と治療の最先端　発作性夜間ヘモグロビン尿症（PNH：paroxysmal nocturnal hemoglobinuria）：最近の話題2016
- Author(s)
  西村純一
- Organizer
  第17回日本検査血液学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-08-06
- Invited
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] PNHの診断と治療：最近の話題2016
- Author(s)
  西村純一
- Organizer
  日本輸血・細胞治療学会九州支部会　第63回総会・第84回例会
- Place of Presentation
  KITENビルコンベンションホール,（宮崎県宮崎市）
- Invited
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] PNHの新たな見解　PNH:疾患・診断・治療2016
- Author(s)
  西村純一
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] A Clinical Significance and Time-Dependent Change of Pnh Clone Size in Patients with Bone Barrow Failure Syndrome: Japanese Multi-Centre Prospective Study2016
- Author(s)
  Shirasugi Y, Sugimori C, Noji H, Shichishima T, Obara1 N, Chiba1 S, Ninomiya H, Nakamura Y, Ando K, Yonemura Y, Kawaguchi T, Hosokawa K, Ueda Y, Nishimura J, Kanakura Y, Nakao S
- Organizer
  21st Congress of the European Hematology Association
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2016-06-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] PNH and Genetic Variants in C5 Confers Poor response to the Anti-C5 Monoclonal Antibody Eculizumab2016
- Author(s)
  Nishimura J
- Organizer
  The 9th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
- Place of Presentation
  Taipei International Convention Center, Taipei, Taiwan
- Year and Date
  2016-10-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] The First Follow-up Data Analysis of Patients with Acquired Bone Marrow Failure Harboring a Small Population of PNH-Type Cells in the Japanese, Multicenter, Prospective Study Optima2016
- Author(s)
  Ueda Y, Nishimura J, Sugimori C, Hosokawa K, Yonemura Y, Obara N, Noji H, Nakamura Y, Shirasugi Y, Ando K, Shichishima T, Ninomiya H, Chiba S, Kawaguchi T, Kanakura Y, Nakao S
- Organizer
  The American Society of Hematology 58th Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] Paroxysmal nocturnal hemoglobinuria caused by PIGT mutations; Atypical PNH2016
- Author(s)
  Yoshiko Murakami, Michi Kawamoto, Norimitsu Inoue, Makiko Osato, Shogo Murata, Sho Murase, Hajime Yoshimura, Yasutaka Ueda, Jun-ichi Nishimura, Yuzuru Kanakura, Nobuo Kohara, and Taroh Kinoshita
- Organizer
  The 58th ASH Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15362
[Presentation] Paroxysmal Nocturnal Hemoglobinuria Caused By Pigt Mutations; Atypical PNH2016
- Author(s)
  Murakami Y, Kawamoto M, Inoue N, Osato M, Murata S, Murase S, Yoshimura H, Ueda Y, Nishimura J, Kanakura Y, Kohara N, Kinoshita T
- Organizer
  The American Society of Hematology 58th Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Emerging issues in the era of eculizumab treatment with PNH: an institutional experience and review2016
- Author(s)
  高森　弘之、植田　康敬、大里　真幸子、林　悟、西村　純一、金倉　譲
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県　横浜市）
- Year and Date
  2016-10-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] 12 Weeks Safety and Efficacy Results of a Novel C5 Inhibitor Coversin in PNH with Resistance to Eculizumab Due to Complement C5 Polymorphism2016
- Author(s)
  Langemeijer S , Davies WW, Nunn M, Nishimura J, Kanakura Y, Blijlevens N, Nijziel M, Muus P
- Organizer
  21st Congress of the European Hematology Association
- Place of Presentation
  Bella Center, Copenhagen, Denmark
- Year and Date
  2016-06-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] PNH溶血に対する抗補体薬効果判定におけるヘモジデリン測定の有用性2015
- Author(s)
  植田康敬、堀田真希、小林渉、西村純一，大里真幸子、林悟，日高洋、金倉譲
- Organizer
  第52回補体シンポジウム
- Place of Presentation
  名古屋大学医学部附属病院（愛知県名古屋市）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Coversin Blocked in Vitro Hemolysis in an Eculizumab-Resistant PNH Patient with the C5 Polymorphism (c.2654G>A)2015
- Author(s)
  Yasutaka Ueda, Makiko Osato, Wynne Weston-Davies, Miles A Nunn, Satoru Hayashi, Jun-Ichi Nishimura, Yuzuru Kanakura
- Organizer
  American Society of Hematology annual meeting 2015
- Place of Presentation
  Orange County Convention Center (Florida, U.S.A.)
- Year and Date
  2015-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09502
[Presentation] Coversin Blocked in Vitro Hemolysis in an Eculizumab-Resistant PNH Patient with the C5 Polymorphism (c.2654G>A)2015
- Author(s)
  Ueda Y, Osato M, Weston-Davies W, Nunn MA, Hayashi S, Nishimura J, Kanakura Y
- Organizer
  The American Society of Hematology 57th Annual Meeting
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Genetic Variants in C5 Confers Poor response to the Anti-C5 Monoclonal Antibody Eculizumab2015
- Author(s)
  Nishimura J
- Organizer
  2015 Dasan Conference
- Place of Presentation
  Saintmare, Busan, Korea
- Year and Date
  2015-12-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Clinical features and QOL evaluation of Japanese PNH patients in the International PNH Registry2015
- Author(s)
  Sakurai M, Okamoto S, Usuki K, Nishimura J, Kawaguchi T, Ninomiya H, Shichishima T, Okada M, Nakakuma H, Nakao S, Kanakura Y
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ホテル日航金沢（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] The interim analysis of prospective observational study with PNH-type cells in Japanese patients with bone marrow failure (The OPTIMA study : Observation of PNH-type cells in Japanese patients with bone marrow failure syndrome and in those suspected of having PNH study).2015
- Author(s)
  Obara1 N, Chiba1 S, Hosokawa K, Sugimori C, Yamamoto M, Noji H, Yonemura Y, Nakamura Y, Ando K, Kawaguchi T, Shichishima T, Ninomiya H, Nishimura J, Kanakura Y, Nakao S
- Organizer
  20th Congress of the European Hematology Association
- Place of Presentation
  Vienna, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Analysis of the data from the 4th year post marketing surveillance (PMS) of eculizumab2015
- Author(s)
  Ninomiya H, Obara1 N, Chiba1 S, Usuki K, Nishiwaki K, Matsumura I, Shichishima T, Okamoto S, Nishimura J, Ohyashiki K, Nakao S, Ando K, Kawaguchi T, Nakakuma H, Hamada Y, Shimono A, Kinoshita T, OzawaK, Omine M, Kanakura Y
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ホテル日航金沢（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] A case of PNH who achieved spontaneousremission after eculuzumab treatment2015
- Author(s)
  Ueda Y, Nishimura J, Osato M, Hayashi S, Tomiyama Y, Kanakura Y
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ホテル日航金沢（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] The Interim Analysis of the OPTIMA (Observation of GPI-Anchored Protein-Deficient [PNH-type] Cells in Japanese Patients with Bone Marrow Failure Syndrome and in Those Suspected of Having PNH).2015
- Author(s)
  Sugimori C, Noji H, Shichishima T, Obara1 N, Chiba1 S, Ninomiya H, Nakamura Y, Ando K, Hosokawa K, Yamamoto M, Yonemura Y, Kawaguchi T, Nishimura J, Kanakura Y, Nakao S
- Organizer
  The 6th JSH international symposium 2015
- Place of Presentation
  軽井沢プリンスホテル（長野県北佐久郡）
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] OPTIMA試験：高精度フローサイトメトリ法によるGPIアンカー膜蛋白欠損血球の測定法の臨床的意義 -中間報告（2015年続報）-2015
- Author(s)
  林悟，植田康敬、西村純一，細川晃平，杉盛千春，米村雄士，小原直，中村嘉彦，野地秀義，七島勉，安藤潔，二宮治彦，千葉滋，川口辰哉，金倉譲，中尾眞二
- Organizer
  第52回補体シンポジウム
- Place of Presentation
  名古屋大学医学部附属病院（愛知県名古屋市）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Improvement of coagulation markers, but not hemolytic markers, in a PNH case treated with eculizumab2015
- Author(s)
  Noji H, Takahashi H, Nishimura J, Shichishima A, Takeishi Y, Kinoshita T, Kanakura Y, Shichishima T
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ホテル日航金沢（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] C5 Polymorphism in a Dutch Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) and No Asian Ancestry, Resistant to Eculizumab, but in Vitro Sensitive to Coversin2015
- Author(s)
  Langemeijer S, Nishimura J, Weston-Davies W, Nunn MA, Kanakura Y, Mackie IJ, Muus P
- Organizer
  The American Society of Hematology 57th Annual Meeting
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Genetic variants in C5 and poor response to eculizumab2014
- Author(s)
  西村純一
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場, 大阪
- Year and Date
  2014-10-31
- Invited
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] Genetic variants in C5 confers poor response to the anti-C5 monoclonal antibody eculizumab2014
- Author(s)
  Nishimura J
- Organizer
  7th International Conference on Complement Therapeutics
- Place of Presentation
  Aldemar Olympia Hotel, Olympia, Greece
- Year and Date
  2014-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461447
[Presentation] PNHの診断とマネージメント2011
- Author(s)
  西村純一
- Organizer
  第50回日本血液学会中国四国地方会
- Place of Presentation
  岡山コンベンションセンター、岡山(招待講演)
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] PNHの診断とマネージメント2011
- Author(s)
  西村純一
- Organizer
  第50回日本血液学会春季北海道地方会ランチョンセミナー
- Place of Presentation
  岡山
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Fatigue and impaired quality of life in patients with paroxysmal nocturnal hemoglobinuria (PNH) is associated with hemolysis, but not with anemia.2010
- Author(s)
  金倉譲、西村純一, ら
- Organizer
  第15回ヨーロッパ血液学会
- Place of Presentation
  The Gran Via Conference Center, Barcelona (Spain)
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Fatigue and impared quality of life in patients with paroxysmal nocturnal hemoglobinuria (PNH) is associated with hemolysis, but not with anemia.2010
- Author(s)
  金倉譲(1番目), 西村純一(10番目), 他13名
- Organizer
  15th Congress of the European Hematology Association
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Expression of HMGA2 in blood cells from patients with paroxysmal nocturnal hemoglobinuria.2010
- Author(s)
  西村純一、金倉譲, ら
- Organizer
  第52回米国血液学会
- Place of Presentation
  Orange County Convention Center, Orlando (USA)
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Expression of HMGA2 in blood cells from patients with paroxysmal nohemoglobinuria.2010
- Author(s)
  Murakami Y, 西村純一(5番目), 金倉譲(6番目), 他5名
- Organizer
  The American Society of Hematology 52nd Annual meeting.
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 発作性夜間ヘモグロビン尿症(PNH)と補体:日本人PNH患者に対するソリリスの有効性および安全性:AEGIS試験&継続投与試験2010
- Author(s)
  西村純一
- Organizer
  第47回補体シンポジウムランチョンセミナー
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 発作性夜間ヘモグロビン尿症に対する新規治療薬エクリズマブの開発2010
- Author(s)
  西村純一
- Organizer
  第93回近畿血液学地方会
- Place of Presentation
  テイジンホール、大阪(招待講演)
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 血液難病の制御:発作性夜間ヘモグロビン尿症に対する新規治療薬エクリズマブの開発2010
- Author(s)
  西村純一
- Organizer
  第93回近畿血液学地方会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 日本人PNH患者に対するソリリスの有効性および安全性:AEGIS試験&継続投与試験2010
- Author(s)
  西村純一
- Organizer
  第47回補体シンポジウム
- Place of Presentation
  コラッセ福島、福島(招待講演)
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Wnt pathway is upregulated in blood cellfrom patients with paroxysmal nocturnal hemoglobinuria.2009
- Author(s)
  Murakami Y, Nishimura J(5番目), Kanakura Y(6番目), 他5名
- Organizer
  The American Society of Hematology 51st Annual meeting.
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] PNHの四方山話(Inside Story)2009
- Author(s)
  西村純一
- Organizer
  第44回日本血液学会春季北海道地方会特別講演
- Place of Presentation
  旭川
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Chronic renal insufficiency in Japanese patients with paroxysmal nocturnal hemoglobinuria (PNH) : Improvement with Eculizumab treatment in the long-term follow-up of the AEGIS study2009
- Author(s)
  金倉譲、西村純一, ら
- Organizer
  第51回米国血液学会
- Place of Presentation
  Ernest N、Morial Conventionセンター(ニューオリンズ、米国)
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Safety and efficacy of Eculizumab in Japanese PNH patients : AEGIS phase II clinical study results2009
- Author(s)
  金倉譲, 西村純一, ら
- Organizer
  第71回日本血液学会学術総会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 本邦PNH症例における補体阻害剤(Eculizumab)の安全性と有効性:AEGIS第2相臨床試験2009
- Author(s)
  西村純一、金倉譲, ら
- Organizer
  第46回補体シンポジウム
- Place of Presentation
  九州大学西新プラザ(福岡)
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Safety and efficacy of Eculizumab in Japanese PNH patients : AEGIS phase II clinical study results2009
- Author(s)
  金倉譲(1番目), 西村純一(10番目), 他13名
- Organizer
  第71回日本血液学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Chronic renal insufficiency in Japanese patients with paroxysmal nocturnal hemoglobinuria (PNH) : Improvement with Eculizumab treatment in the long-term follow-up of the AEGIS study.2009
- Author(s)
  金倉譲(1番目), 西村純一(10番目), 他13名
- Organizer
  The American Society of Hematology 51st Annual meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 特別講演 PNHの四方山話(Inside Story)2009
- Author(s)
  西村純一
- Organizer
  第44回日本血液学会春季北海道地方会
- Place of Presentation
  旭川大雪クリスタルホール (北海道)
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 発作性夜間血色素尿症患者におけるHMGA2の発現について2009
- Author(s)
  Murakami Y, Kanakura Y(3番目), Nishimura J(4番目), 他5名
- Organizer
  第71回日本血液学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] RNA aptamer therapy for vaso-occlusion in sickle cell disease.2008
- Author(s)
  Burnette AD, Nishimura J(2番目), 他6名
- Organizer
  4th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 発作性夜間ヘモグロビン尿症の新規治療法の開発2008
- Author(s)
  西村純一
- Organizer
  第70回日本血液学会総会コーポレートセミナー
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Expression of HMGA2 in blood cells from patients with paroxysmal nohemoglobinuria.2008
- Author(s)
  Murakami Y, Nishimura J(4番目), Kanakura Y(5番目), 他4名
- Organizer
  XXII International Complement Workshop
- Place of Presentation
  Basel, Switzland
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Expression of HMGA2 in blood cells from patients with paroxysmal nohemoglobinuria.2008
- Author(s)
  Murakami Y, Nishimura J(5番目), Kanakura Y(6番目), 他5名
- Organizer
  The American Society of Hematology 50th Annual meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] Safety and efficacy of the terminal complement Inhibitor Eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: Aegis phase II clinical study results.2008
- Author(s)
  金倉譲(1番目), 西村純一(10番目), 他13名
- Organizer
  The American Society of Hematology 50th Annual meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-20591123
[Presentation] 発作性夜間ヘモグロビン尿症の新規治療法の開発2008
- Author(s)
  西村純一
- Organizer
  第70回日本血液学会総会コーポレートセミナ
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20591123

1. Ueda Yasutaka (30533848)

# of Collaborated Projects: 6 results

# of Collaborated Products: 34 results
2. KANAKURA Yuzuru (20177489)

# of Collaborated Projects: 4 results

# of Collaborated Products: 58 results
3. Takamori Hiroyuki (80792077)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. 保仙直毅 (10456923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Murakami Yoshiko (00304048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Kinoshita Taroh (10153165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Inoue Norimitsu (80252708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 柴山浩彦 (60346202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 南谷泰仁 (60451811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 藤岡龍哉 (70403045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松岡由和 (70533420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 松村到

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 荒瀬規子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

nishimura junichi 西村 純一

NISHIMURA Jun-ichi 西村 純一

NISHIMURA Jun-Ichi 西村 純一

Research Projects

Research Products

Co-Researchers

Unraveling the mechanism of poor response to anti-comlement drug in cold agglutinin disease treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PNHクローンの起源と変遷

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the most appropriate therapeutic target for PNH

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis for hematopoietic dynamics of clonal expansion in PNHPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanism of pathogenesis of paroxysmal nocturnal hemoglobinuria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exhaustive analysis for clinical application of anti-complement drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysos of metabolic abnormality which causes clonal expansion in Paroxysmal nocturnal hemoglobinuria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of eculizumab therapeutic response to patients with PNHPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of target therapeutic for PNH using RNA aptamerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 内科学 第11版2017

Author(s)

Total Pages

Publisher

Data Source

[Book] 貧血学2017

Author(s)

Total Pages

Publisher

Data Source

[Book] Paroxysmal Nocturnal Hemoglobinuria From Bench to Bedside2017

Author(s)

Total Pages

Publisher

Data Source

[Book] Paroxysmal Nocturnal Hemoglobinuria From Bench to Bedside2017

Author(s)

Total Pages

Publisher

Data Source

nishimura junichi 西村純一

NISHIMURA Jun-ichi 西村純一

NISHIMURA Jun-Ichi 西村純一

[Book] 内科学第11版2017

[Book] ブラッシュアップ骨髄不全症（松田晃編）2015

[Book] 発作性夜間ヘモグロビン尿症（PNH）～遺伝子異常の解析から新規治療薬の臨床・開発まで～（金倉譲、西村純一編）2015