Sonoshita Masahiro 園下将大

… Alternative Names

SONOSHITA Masahiro 園下将大

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Researcher Number	80511857
Other IDs	https://orcid.org/0000-0003-2890-336X
Affiliation (Current)	2025: 北海道大学, 遺伝子病制御研究所, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 北海道大学, 遺伝子病制御研究所, 教授 2015: 京都大学, 大学院医学研究科, 准教授 2012 – 2015: 京都大学, 医学(系)研究科(研究院), 准教授 2012: 京都大学, 大学院・医学研究科, 准教授 2011: 京都大学, 工学研究科, 講師 2010 – 2011: 京都大学, 医学研究科, 講師 2008 – 2009: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 50:Oncology and related fields / Complex systems / Medium-sized Section 47:Pharmaceutical sciences and related fields / Tumor biology Except Principal Investigator Pathological medical chemistry / Basic Section 50010:Tumor biology-related / Basic Section 57060:Surgical dentistry-related / Biological Sciences
Keywords	Principal Investigator 膵がん / ショウジョウバエ / 表現型スクリーニング / キナーゼ / 微小重力 / がん治療薬 / 個別化医療 / 薬物抵抗性 / 遺伝学 / 頑健性 … More / 治療抵抗性 / モデル動物 / 膵臓がん / 新規治療薬 / 異分野融合 / がん / シンギュラリティ / 少数細胞 / アルツハイマー病 / 遺伝学スクリーニング / タウオパチー / 認知症 / Notch / Aes / 大腸がん / 遺伝子改変動物 / 転移 … More Except Principal Investigator 転移 / ショウジョウバエ / 新規治療法開発 / 膵がん / 消化器がん / ケモカイン / Notch / 分子腫瘍学 / 病理学 / マイクロアレイ / 癌 / モデルハエ / オートファジー / 新規治療法 / 膵臓がん / ショウジョウバエモデル / 新規治療法の開発 / リボフラビン / 炎症性サイトカイン / IL-17 / 口腔カンジダ症 / 慢性炎症 / メタ16S解析 / 口腔癌 / 唾液 / マイクロバイオーム解析 / がん転移 / 予後診断 / TGF-betaシグナル / Notchシグナル / 消化器 / がん / TRIO / ABL / NOTCH / AES / 予後マーカー / 浸潤 / 消化器癌 / 未分化骨髄球 / マウスモデル / CXCR3 / 細胞・組織 / 間質細胞 / COX-2 / Apc / トランスジェニックマウス / Lkb1 / MMP7 / mTORC1 / 遺伝子改変マウス / シグナル伝達 / 血管新生 / 炎症 Less

遺伝子型に立脚した膵がん個別化医療開発基盤の創出Principal Investigator
- Principal Investigator
  
  園下将大
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hokkaido University
重力変動が膵がん形質に与える影響の解明Principal Investigator
- Principal Investigator
  
  園下将大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Hokkaido University
オートファジーを標的とする膵がんの新規治療法の開発
- Principal Investigator
  
  大塩貴子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hokkaido University
Development of Oral Cancer Prevention Methods Based on Analysis of Oral Bacterial Flora and Inflammatory Cytokines in Saliva
- Principal Investigator
  
  大賀則孝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hokkaido University
Indentifying the basis for the robustness in pancreatic cancer to develop novel therapeuiticsPrincipal Investigator
- Principal Investigator
  
  Sonoshita Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hokkaido University
Developing a novel therapy for pancreatic cancer targeting the riboflavin pathway
- Principal Investigator
  
  Ooshio Takako
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hokkaido University
Developing a novel strategy to treat dementia through chemical geneticsPrincipal Investigator
- Principal Investigator
  
  Sonoshita Masahiro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Hokkaido University
少数細胞が規定する膵臓がん発生過程の解明Principal Investigator
- Principal Investigator
  
  園下将大
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Studies on digestive system cancer metastasis using mouse models
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Roles of Notch signaling pathway in colon cancer metastasisPrincipal Investigator
- Principal Investigator
  
  SONOSHITA Masahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto University
StudiesonMetastasisofDigestiveCancersUsingMouseModels
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Studies on digestive cancer metastasis using mouse models
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Epitehial-stromal interactions and molecularly targeted therapy
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

[Journal Article] Concurrent targeting of GSK3 and MEK as a therapeutic strategy to treat pancreatic ductal adenocarcinoma2024
- Author(s)
  Fukuda Junki、Kosuge Shinya、Satoh Yusuke、Sekiya Sho、Yamamura Ryodai、Ooshio Takako、Hirata Taiga、Sato Reo、Hatanaka Kanako C.、Mitsuhashi Tomoko、Nakamura Toru、Matsuno Yoshihiro、Hatanaka Yutaka、Hirano Satoshi、Sonoshita Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: 4 Issue: 4 Pages: 1333-1345
- DOI
  10.1111/cas.16100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06667, KAKENHI-PROJECT-23K27450
[Journal Article] Drosophila Screening Identifies Dual Inhibition of MEK and AURKB as an Effective Therapy for Pancreatic Ductal Adenocarcinoma2023
- Author(s)
  Sekiya Sho、Fukuda Junki、Yamamura Ryodai、Ooshio Takako、Satoh Yusuke、Kosuge Shinya、Sato Reo、Hatanaka Kanako C.、Hatanaka Yutaka、Mitsuhashi Tomoko、Nakamura Toru、Matsuno Yoshihiro、Hirano Satoshi、Sonoshita Masahiro
- Journal Title
  
  Cancer Research
  
  Volume: 83 Issue: 16 Pages: 2704-2715
- DOI
  10.1158/0008-5472.can-22-3762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06667
[Journal Article] ショウジョウバエを活用した計画的な個体レベルのセレンディピティによるがん研究の加速.2022
- Author(s)
  佐藤悠介, 園下将大.
- Journal Title
  
  医学のあゆみ
  
  Volume: 282巻 Pages: 798-800
- Data Source
  KAKENHI-PROJECT-20H03524
[Journal Article] Tiny Drosophila makes giant strides in cancer research2021
- Author(s)
  Yamamura Ryodai、Ooshio Takako、Sonoshita Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 2 Pages: 505-514
- DOI
  10.1111/cas.14747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05412, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03524, KAKENHI-PROJECT-21K14762, KAKENHI-PROJECT-20K07558
[Journal Article] Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network2019
- Author(s)
  Ung Peter M. U.、Sonoshita Masahiro、Scopton Alex P.、Dar Arvin C.、Cagan Ross L.、Schlessinger Avner
- Journal Title
  
  PLoS Computational Biology
  
  Volume: 15 Issue: 4 Pages: e1006878-e1006878
- DOI
  10.1371/journal.pcbi.1006878
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05412
[Journal Article] Promotion of Colorectal Cancer Invasion and Metastasis Through Activation of Notch-Dab1-Abl-RhoGEF Protein Trio.2015
- Author(s)
  Sonoshita M, Itatani Y, Kakizaki F, Sakimura K, Terashima T, Katsuyama Y, Sakai Y, Taketo MM.
- Journal Title
  
  Cancer Discov.
  
  Volume: 5 Issue: 2 Pages: 198-211
- DOI
  10.1158/2159-8290.cd-14-0595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300126, KAKENHI-PROJECT-24650177, KAKENHI-PROJECT-26440112, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25253022
[Journal Article] Characterization of Aes nuclear foci in colorectal cancer cells2015
- Author(s)
  Yoshiro Itatani1,2, Masahiro Sonoshita1, Fumihiko Kakizaki1, Katsuya Okawa3, Stefano Stifani4, Hideaki Itoh5, Yoshiharu Sakai2 and M. Mark Taketo1,2,*
- Journal Title
  
  J. Biochem.
  
  Volume: 159 Issue: 1 Pages: 133-140
- DOI
  10.1093/jb/mvv077
- NAID
  40020725723
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253022
[Journal Article] Molecular mechanisms of liver metastasis2011
- Author(s)
  Kawada K, HaSegawa S, Murakami T, Itatani Y, Hosogi H, Sonoshita M, Kitamura T, Fujishita T, Iwamoto M, Matsumoto T, Matsusue R, Hida K, Akiyaraa G, Okoshi K, Yamada M, Kawamura J, Taketo MM, Sakai Y
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 16 Issue: 5 Pages: 464-472
- DOI
  10.1007/s10147-011-0307-2
- NAID
  10030246531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005, KAKENHI-PROJECT-22791276, KAKENHI-PROJECT-23680088
[Journal Article] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling2011
- Author(s)
  Sonoshita M, Aoki M, Fuwa H, Aoki K, Hosogi H, Sakai Y, Hashida H, Takabayashi A, Sasaki M, Robine S, Itoh K, Yoshioka K, Kakizaki F, Kitamura K, Oshima M, and Taketo MM.
- Journal Title
  
  Cancer Cell
  
  Volume: 19 Pages: 125-137
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling.2011
- Author(s)
  Sonoshita M, Aoki M, Fuwa H, Aoki K, Hosogi H, Sakai Y, Hashida H, Takabayashi A, Sasaki M, Robine S, Itoh K, Yoshioka K, Kakizaki F, Kitamura K, Oshima M, Taketo MM.
- Journal Title
  
  Cancer Cell
  
  Volume: 19 Pages: 125-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229005
[Journal Article] Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes2007
- Author(s)
  Kawada, K., Hosogi, H., Sonoshita, M., Sakashita, H., Manabe, T., Shimahara, Y., Sakai, Y., Takabayashi, A., Oshima, M., Taketo, M.M
- Journal Title
  
  Oncogene 26
  
  Pages: 4679-4688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209010
[Journal Article] Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes.2007
- Author(s)
  Kawada, K., Hosogi, H., Sonoshita, M., Sakashita, H., Manabe, T., Shimahara, Y., Sakai, Y., Takabayashi, A, Oshima, M., Taketo, M.M.
- Journal Title
  
  Oncogene 26
  
  Pages: 4679-4688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016032
[Patent] AGENT FOR TREATING OR PREVENTING CANCER, AND COMBINATION OF RF PATHWAY INHIBITOR AND MEK INHIBITOR FOR TREATING OR PREVENTING CANCER2023
- Inventor(s)
  OOSHIO, SONOSHITAら
- Industrial Property Rights Holder
  OOSHIO, SONOSHITAら
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Acquisition Date
  2024
- Overseas
- Data Source
  KAKENHI-PROJECT-23K06667
[Patent] AGENT FOR TREATING OR PREVENTING CANCER, AND COMBINATION OF RF PATHWAY INHIBITOR AND MEK INHIBITOR FOR TREATING OR PREVENTING CANCER2022
- Inventor(s)
  大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
- Industrial Property Rights Holder
  北海道大学、第一薬科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20K07558
[Patent] 治療又は予防剤、及びがんの治療又は予防のためのRF経路阻害剤とMEK阻害剤との組み合わせ2022
- Inventor(s)
  大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
- Industrial Property Rights Holder
  国立大学法人北海道大学、学校法人都築学園
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-026434
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K07558
[Patent] 治療又は予防剤、及びがんの治療又は予防のためのRF経路阻害剤とMEK阻害剤との組み合わせ2022
- Inventor(s)
  大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
- Industrial Property Rights Holder
  北海道大学、第一薬科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K07558
[Patent] AGENT FOR TREATING OR PREVENTING CANCER, AND COMBINATION OF RF PATHWAY INHIBITOR AND MEK INHIBITOR FOR TREATING OR PREVENTING CANCER2022
- Inventor(s)
  大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
- Industrial Property Rights Holder
  国立大学法人北海道大学、学校法人都築学園
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20K07558
[Patent] 抗がん剤をスクリーニングする方法及び膵がんの治療のためのキナーゼ阻害剤の組み合わせ2022
- Inventor(s)
  園下将大、関谷翔、平野聡
- Industrial Property Rights Holder
  園下将大、関谷翔、平野聡
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-503384
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03524
[Patent] がんの治療又は予防剤、及びがんの治療又は予防のためのRF経路阻害剤とMEK阻害剤との組み合わせ2021
- Inventor(s)
  大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
- Industrial Property Rights Holder
  国立大学法人北海道大学、学校法人都築学園
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-029585
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K07558
[Patent] がんの治療又は予防剤、及びがんの治療又は予防のためのRF経路阻害剤とMEK阻害剤との組み合わせ2021
- Inventor(s)
  大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
- Industrial Property Rights Holder
  大塩貴子、園下将大、市川聡、佐藤悠介、藤井清永
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-029585
- Filing Date
  2021
- Data Source
  KAKENHI-PUBLICLY-19H05412
[Patent] 抗がん剤をスクリーニングする方法及び膵がんの治療のためのキナーゼ阻害剤の組み合わせ2021
- Inventor(s)
  園下将大, 関谷翔
- Industrial Property Rights Holder
  園下将大, 関谷翔
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H03524
[Patent] がんの治療又は予防剤、及びがんの治療又は予防のためのRF経路阻害剤とMEK阻害剤との組み合わせ2021
- Inventor(s)
  大塩貴子, 園下将大, 市川聡, 佐藤悠介, 藤井清永
- Industrial Property Rights Holder
  大塩貴子, 園下将大, 市川聡, 佐藤悠介, 藤井清永
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-029585
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20H03524
[Patent] 抗がん剤をスクリーニングする方法及び膵がんの治療のためのキナーゼ阻害剤の組み合わせ2021
- Inventor(s)
  園下将大、関谷翔
- Industrial Property Rights Holder
  園下将大、関谷翔
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PUBLICLY-19H05412
[Patent] 抗がん剤をスクリーニングする方法及び膵がんの治療のためのキナーゼ阻害剤の組み合わせ2020
- Inventor(s)
  園下将大、関谷翔
- Industrial Property Rights Holder
  園下将大、関谷翔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-032112
- Filing Date
  2020
- Data Source
  KAKENHI-PUBLICLY-19H05412
[Patent] Methods fro Determining Prognosis of Cancer2015
- Inventor(s)
  Makoto Taketo, Masahiro Sonoshita, Yoshiharu Sakai, Kennji Kawada, Yoshiro Itatani
- Industrial Property Rights Holder
  Kyoto University
- Filing Date
  2015-11-13
- Acquisition Date
  2018-01-09
- Overseas
- Data Source
  KAKENHI-PROJECT-25253022
[Patent] METHODS FOR DETERMINING PROGNOSIS OF CANCER2014
- Inventor(s)
  武藤誠、園下将大、坂井義治、河田健二、板谷喜朗
- Industrial Property Rights Holder
  武藤誠、園下将大、坂井義治、河田健二、板谷喜朗
- Industrial Property Rights Type
  特許
- Filing Date
  2014-06-03
- Overseas
- Data Source
  KAKENHI-PROJECT-25253022
[Patent] METHOD FOR DETERMINING PROGNOSIS OF CANCER2013
- Inventor(s)
  武藤誠、園下将大、坂井義治、河田健二、板谷喜朗
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-25253022
[Patent] Methods for Determining Prognosis of Cancer
- Inventor(s)
  Makoto Taketo Masahiro Sonoshita, Yoshiharu Sakai, Kenji Kawada, Yoshiro Itatani
- Industrial Property Rights Holder
  Kyoto Univeristy
- Description
  2016-526147(公開) 2016-0103133(公開) 105264381(公開) 2997378(公開) 2912526(出願) 2015/11/13 2015/11/13 2015/11/11 2015/11/16 2015/11/13
- Overseas
- Data Source
  KAKENHI-PROJECT-25253022
[Presentation] Identifying RFK and MEK as potential therapeutic targets for pancreatic cancer through a Drosophila screening2023
- Author(s)
  Ooshio T. and Sonoshita M.
- Organizer
  6th Edition of International Cancer Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06667
[Presentation] Whole-animal approaches using Drosophila to develop novel therapeutic candidates for pancreatic cancer treatment2022
- Author(s)
  Msahiro Sonoshita
- Organizer
  7th JCA-AACR Special Joint Conference
- Invited
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] Whole-animal approaches using Drosophila to develop novel drugs for cancer treatment2022
- Author(s)
  Msahiro Sonoshita
- Organizer
  12th AACR-JCA Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] Identifying a novel therapeutic candidate for pancreatic cancer using a Drosophila model2022
- Author(s)
  Takako Ooshio, Yusuke Satoh, Kiyonaga Fujii, Junki Fukuda, Tomoki Ishihara, and Masahiro Sonoshita
- Organizer
  Serendipity Workshop 2022
- Data Source
  KAKENHI-PROJECT-20K07558
[Presentation] 個体表現型スクリーニングによる新規がん治療薬開発の加速2021
- Author(s)
  園下将大
- Organizer
  第30回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] Drosophila approaches to develop novel cancer drugs2021
- Author(s)
  Masahiro Sonoshita
- Organizer
  The TARA International Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] A whole-animal platform to advance drug discovery2021
- Author(s)
  Masahiro Sonoshita
- Organizer
  Imperial College London Life Sciences Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] 個体表現型スクリーニングが加速する新規がん治療薬開発2021
- Author(s)
  園下将大
- Organizer
  第25回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] Determining therapeutic vulnerabilities in pancreatic cancer using a whole-animal platform2021
- Author(s)
  Masahiro Sonoshita
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] ショウジョウバエを活用したがん治療薬の探索2021
- Author(s)
  園下将大
- Organizer
  文部科学省科学研究費補助金新学術領域「細胞ダイバース」第６回領域会議
- Invited
- Data Source
  KAKENHI-PROJECT-20H03524
[Presentation] Promotion of Colorectal Cancer Invasion and Metastasis through Activation of Notch-Dab1-Abl-RhoGEF Protein Trio2015
- Author(s)
  Masahiro Sonoshita1 , Yoshiro Itatani1,2 , Fumihiko Kakizaki1 and Yoshiharu Sakai2, M. Mark Taketo1,2
- Organizer
  AACR Tumor Metastasis Meeting
- Place of Presentation
  Austin, TX, USA
- Year and Date
  2015-11-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253022
[Presentation] 転写因子Rbpjを介したNotch シグナルによる大腸がん転移の促進2013
- Author(s)
  園下将大, 武藤　誠
- Organizer
  第22回　日本がん転移学会学術集会、総会
- Place of Presentation
  松本市
- Invited
- Data Source
  KAKENHI-PROJECT-25253022
[Presentation] Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling（口頭）2012
- Author(s)
  園下将大
- Organizer
  日本癌学会
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling2012
- Author(s)
  M. Sonoshita
- Organizer
  日本癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23680088
[Presentation] Critical roles of Notch signaling pathway in colon cancer metastasis2012
- Author(s)
  M. Sonoshita
- Organizer
  国際がん転移学会
- Place of Presentation
  オーストラリア、ブリスベン
- Data Source
  KAKENHI-PROJECT-23680088
[Presentation] Critical roles of Notch signaling pathway in colon cancer metastasis（ポスター）2012
- Author(s)
  園下将大
- Organizer
  国際がん転移学会
- Place of Presentation
  オーストラリア、ブリスベン
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] Stimulation of colon cancer metastasis by Notch signaling2011
- Author(s)
  M.Sonoshita
- Organizer
  第70回日本癌学会学術総会シンポジウムUse of animal models for advances in cancer prevention and treatment(英語)
- Place of Presentation
  名古屋コングレスセンター(招待講演)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23680088
[Presentation] Stimulation of colon cancer metastasis by Notch signaling2011
- Author(s)
  園下将大
- Organizer
  第70回日本癌学会学術総会シンポジウムUse of animal models for advances in cancer prevention and treatment
- Place of Presentation
  名古屋コングレスセンター(英語、招待講演)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] Stimulation of colon cancer metastasis by Notch signaling2011
- Author(s)
  M. Sonoshita
- Organizer
  第70回日本癌学会学術総会シンポジウム Use of animal models for advances in cancer prevention and treatment (英語)
- Place of Presentation
  名古屋コングレスセンター
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23680088
[Presentation] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling2010
- Author(s)
  園下将大
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸、日本
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] ワークショップ 3W11 Notchシグナル:疾患解明を目指して "Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling"2010
- Author(s)
  園下将大
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling2010
- Author(s)
  園下将大
- Organizer
  Notch研究会
- Place of Presentation
  千葉、日本
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling2010
- Author(s)
  園下将大
- Organizer
  Notch研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21229005
[Presentation] (Poster) Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling2008
- Author(s)
  Sonoshita, M., Taketo, M.M.
- Organizer
  Notch and Cancer Meeting
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-17016032
[Presentation] Possible involvement of Notch pathway genes in colon cancer metastasis2007
- Author(s)
  Sonoshita, M
- Organizer
  The Notch Meeting
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-19209010
[Presentation] Possible involvement of Notch pathway genes in colon cancer metastasis2007
- Author(s)
  Sonoshita, M
- Organizer
  The Notch Meeting
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-17016032
[Presentation] 大腸がんの悪性化メカニズム（口頭）
- Author(s)
  園下将大
- Organizer
  第４回生命科学阿波おどりシンポジウム
- Place of Presentation
  徳島市
- Data Source
  KAKENHI-PROJECT-21229005

1. TAKETO Makoto (70281714)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. AOKI Masahiro (60362464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. KITAMURA Takanori (10378622)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. Ooshio Takako (80723238)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. 小沼剛 (10631682)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 市川聡 (60333621)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. MIYOSHI Hiroyuki (30362479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 藤井清永 (10278327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 山村凌大 (40880000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. OSHIMA Masanobu (40324610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. OSHIMA Hiroko (80362515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. AOKI Koji (40402862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. FUJISHITA Teruaki (50511870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. KAKIZAKI Fumihiko (00609076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 大賀則孝 (40548202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 北川善政 (00224957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 坂田健一郎 (10826051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 佐藤淳 (60319069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 長谷部晃 (90281815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 五十嵐学 (10374240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 合田圭介 (70518696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 稲田全規 (80401454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 野田展生 (40396297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 寺島俊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sonoshita Masahiro 園下 将大

SONOSHITA Masahiro 園下 将大

Research Projects

Research Products

Co-Researchers

遺伝子型に立脚した膵がん個別化医療開発基盤の創出Principal Investigator

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重力変動が膵がん形質に与える影響の解明Principal Investigator

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オートファジーを標的とする膵がんの新規治療法の開発

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Development of Oral Cancer Prevention Methods Based on Analysis of Oral Bacterial Flora and Inflammatory Cytokines in Saliva

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Indentifying the basis for the robustness in pancreatic cancer to develop novel therapeuiticsPrincipal Investigator

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Developing a novel therapy for pancreatic cancer targeting the riboflavin pathway

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Developing a novel strategy to treat dementia through chemical geneticsPrincipal Investigator

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少数細胞が規定する膵臓がん発生過程の解明Principal Investigator

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Studies on digestive system cancer metastasis using mouse models

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Roles of Notch signaling pathway in colon cancer metastasisPrincipal Investigator

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StudiesonMetastasisofDigestiveCancersUsingMouseModels

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Studies on digestive cancer metastasis using mouse models

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Epitehial-stromal interactions and molecularly targeted therapy

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Sonoshita Masahiro 園下将大

SONOSHITA Masahiro 園下将大