Sakurai Hidetoshi 櫻井英俊

… Alternative Names

櫻井英俊サクライヒデトシ

SAKURAI Hidetoshi 櫻井英俊

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Researcher Number	80528745
Other IDs
Affiliation (Current)	2025: 京都大学, iPS細胞研究所, 准教授
Affiliation (based on the past Project Information) *help	2023: 京都大学, iPS細胞研究所, 准教授 2015 – 2020: 京都大学, iPS細胞研究所, 准教授 2016: 京都大学, iPS細胞研究所, 講師 2015: 京都大学, ips細胞研究所, 准教授 2011 – 2014: 京都大学, iPS細胞研究所, 講師 2012: 京都大学, iPS 細胞研究所, 講師 2010: 京都大学, iPS細胞研究所, 特定拠点講師
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related / Basic Section 49030:Experimental pathology-related / Nerve anatomy/Neuropathology / Experimental pathology / General medical chemistry Except Principal Investigator Metabolomics / Orthopaedic surgery / General pharmacology
Keywords	Principal Investigator iPS細胞 / 病態再現 / 疾患特異的iPS細胞 / 筋ジストロフィー / ウルリッヒ型先天性筋ジストロフィー / ６型コラーゲン / 分泌因子 / 筋再生 / 間葉系間質細胞 / ポンぺ病 … More / トランスジェニックiPS細胞 / 骨格筋幹細胞 / Pompe病 / 酵素補充療法 / 遺伝子治療 / 細胞移植治療 / ポンペ病 / クロマチン構造 / CTGリピート / CTGリピート伸長 / 筋強直性ジストロフィー / 患者由来iPS細胞 / 創薬スクリーニング / 骨格筋細胞 / 細胞内カルシウムイメージング / デュシェンヌ型筋ジストロフィー / 疾患再現 / 中胚葉誘導 / 筋ジストロフィーモデル / 分化誘導 / 骨格筋前駆細胞 / 再生医療 … More Except Principal Investigator 脂肪萎縮症 / インスリン抵抗性 / 脂肪細胞分化 / iPS細胞 / 脂肪細胞 / 幹細胞機能 / 血管内皮細胞 / 脂肪酸受容体 / 骨格筋細胞 / 成因解明 / 先天性脂肪萎縮症 / レスキュー / seipin / 多能性幹細胞 / 疾患特異的iPS細胞 / 肥満症 / ヒトiPS細胞 / 進行性骨化性線維異形成症 / 異所性骨化 / 中胚葉細胞 / ヌードマウス / 細胞治療 Less

Elucidation of the mechanism of skeletal muscle regeneration utilizing iPSC-derived mesenchymal stem cellsPrincipal Investigator
- Principal Investigator
  
  櫻井英俊
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kyoto University
Cell therapy for Pompe disease using iPSC-derived muscle stem cellsPrincipal Investigator
- Principal Investigator
  
  Sakurai Hidetoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kyoto University
Effects of free fatty acid receptors on the differentiation of human skeletal myogenesis.
- Principal Investigator
  
  Imamura Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tottori University
  Shiga University of Medical Science
Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instabilityPrincipal Investigator
- Principal Investigator
  
  SAKURAI Hidetoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
Derivation of human PSC-derived mesodermal cells
- Principal Investigator
  
  Ikeya Makoto
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Analysis of fibrodysplasia ossificans progressive by using iPSCs
- Principal Investigator
  
  Ikeya Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Development of novel therapy for lipodystrophy and obesity using human iPS cells
- Principal Investigator
  
  Noguchi Michio
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
Elucidation of pathogenesis and development of therapy of lipodystrophy using human iPS cell-derived adipocytes
- Principal Investigator
  
  Hosoda Kiminori
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  National Cardiovascular Center Research Institute
  Kyoto University
Cell therapy of adipocytes derived from human iPS cells using cellcontainers and animal disease models
- Principal Investigator
  
  HOSODA Kiminori
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
Modeling Duchenne muscular dystrophy using patient-derived iPS cellsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Hidetoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
Cell therapy for Muscular Dystrophy using myogenic progenitor cells derived from human iPS cellsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Hidetoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University

All 2024 2023 2021 2019 2017 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation Patent

[Journal Article] Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability.2017
- Author(s)
  Ueki J, Nakamori M, Nakamura M, Nishikawa M, Yoshida Y, Tanaka A, Morizane A, Kamon M, Araki T, Takahashi MP, Watanabe A, Inagaki N, Sakurai H.
- Journal Title
  
  Sci Rep.
  
  Volume: 13 Issue: 1 Pages: 42522-42522
- DOI
  10.1038/srep42522
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-15J04853, KAKENHI-PROJECT-25713034, KAKENHI-PROJECT-26430053, KAKENHI-PROJECT-15K15339, KAKENHI-PROJECT-15K21113, KAKENHI-PROJECT-17K16711, KAKENHI-PROJECT-16H05321
[Journal Article] MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis in human induced pluripotent stem cells.2015
- Author(s)
  Hirotaka Iwasaki, Takeshi Imamura, Katsutaro Morino, Takashi Shimosato, Masashi Tawa, Satoshi Ugi, Hidetoshi Sakurai, Hiroshi Maegawa and Tomio Okamura
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 468 Issue: 1-2 Pages: 208-213
- DOI
  10.1016/j.bbrc.2015.10.128
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08229, KAKENHI-PROJECT-25461342
[Journal Article] In vitro characterization and engraftment of adipocytes derived from human induced pluripotent stem cells and embryonic stem cells.2013
- Author(s)
  M. Noguchi, K. Hosoda, E. Mori, M. Nakane, K. Nakao, D. Taura, Y. Yamamoto, T. Kusakabe, M. Sone, H. Sakurai, J. Fujikura, K. Ebihara, K. Nakao
- Journal Title
  
  Stem Cells and Development
  
  Volume: 22(21) Issue: 21 Pages: 2895-2905
- DOI
  10.1089/scd.2013.0113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PLANNED-22126012, KAKENHI-PUBLICLY-23126513, KAKENHI-PROJECT-23591305, KAKENHI-PROJECT-24390237, KAKENHI-PROJECT-25293211, KAKENHI-PROJECT-25461347
[Journal Article] Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Myoshi Myopathy in vitro2013
- Author(s)
  田中章仁, Knut Woltjen, 三宅克也,堀田秋津,池谷真,山本拓也,西野永希子,庄子栄美i,瀬原淳子,真鍋康子,藤井宣晴,花岡和則,江良拓実,山下賢,磯部健一,木村円,櫻井英俊
- Journal Title
  
  PLOS ONE
  
  Volume: 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790383
[Patent] METHOD OF INDUCING DIFFERENTIATION FROM PLURIPOTENT STEM CELL TO SKELETAL MUSCLE PROGENITOR CELLS2010
- Inventor(s)
  櫻井英俊, 坂口泰子, 瀬原淳子
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2010-07-09
- Overseas
- Data Source
  KAKENHI-PROJECT-22790284
[Presentation] Ullrich型先天性筋ジストロフィーの病態改善を目指した細胞移植治療法の確立～移植用細胞源検討～2024
- Author(s)
  後藤萌、竹中菜々、池谷真、櫻井英俊
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K05780
[Presentation] Ullrich型先天性筋ジストロフィーの病態改善を目指した細胞移植治療法の確立～移植用細胞源の検討～2023
- Author(s)
  後藤萌、竹中菜々、池谷真、櫻井英俊
- Organizer
  第10回日本小児理学療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K05780
[Presentation] ポンペ病に対する細胞移植による酵素補充療法の開発2021
- Author(s)
  有本江里、櫻井英俊
- Organizer
  第８回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-18K07067
[Presentation] CRISPR-Cas9による遺伝子編集患者由来iPS細胞を用いた細胞治療と酵素補充療法の組み合わせによるポンぺ病の治療2019
- Author(s)
  有本江里、櫻井英俊
- Organizer
  第7回　若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-18K07067
[Presentation] DM1患者由来iPS細胞を用いた創薬スクリーニングとCTGリピート伸長メカニズムの解明2017
- Author(s)
  加門正義、植木絢子、櫻井英俊、荒木敏之
- Organizer
  第5回　骨格筋カンファレンス
- Place of Presentation
  国立精神・神経医療研究センター（東京都小平市）
- Data Source
  KAKENHI-PROJECT-26430053
[Presentation] ヒトiPS細胞から誘導した未分節体節細胞の分化能の評価2016
- Author(s)
  中島大輝、Cantas Alev、柴田光章、高山了、福田誠、櫻井英俊、戸口田淳也、池谷真
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26670661
[Presentation] microRNA-494はヒトiPS細胞の骨格筋分化において筋線維型制御に関与する2016
- Author(s)
  岩崎広高、今村武史、森野勝太郎、田和正志、下里貴、坂本珠梨、渡邊敦子、卯木智、櫻井英俊、前川聡、岡村富夫
- Organizer
  日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08229
[Presentation] Efficient induction of presomitic mesodermal cells from human iPSCs2015
- Author(s)
  Taiki Nakajima, Mitsuaki Shibata, Satoru Takayama, Makoto Fukuta, Hidetoshi Sakurai, Junya Toguchida, Makoto Ikeya
- Organizer
  第48回日本発生生物学会大会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-26670661
[Presentation] Modeling genetic instability of the CTG repeats in Myotonic Dystrophy type 1 (DM1) patient-derived iPS cell2015
- Author(s)
  Junko UEKI, Masayuki NAKAMORI, Masanori TAKAHASHI, Hidetoshi SAKURAI
- Organizer
  The 10th International Myotonic Dystrophy Consortium Meeting
- Place of Presentation
  PARIS, FRANCE
- Year and Date
  2015-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430053
[Presentation] 疾患特異的iPS細胞を活用した筋疾患研究2014
- Author(s)
  櫻井英俊
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都市
- Year and Date
  2014-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-24790383
[Presentation] Modeling Duchenne muscular dystrophy by patient-derived iPS cells2014
- Author(s)
  Emi Shoji, Sakurai Hidetoshi
- Organizer
  The 7^<th> Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-24790383
[Presentation] Modeling Duchenne muscular dystrophy by patient-derived iPS cells2014
- Author(s)
  Emi Shoji, Hidetoshi Sakurai
- Organizer
  The 7th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-24790383
[Presentation] 転写因子を用いた効率的なヒトiPS細胞からの骨格筋細胞誘導法の確立と細胞療法、疾患モデルへの応用2013
- Author(s)
  田中章仁、櫻井英俊
- Organizer
  第12回　日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790383
[Presentation] デュシェンヌ型筋ジストロフィー患者由来iPS細胞を用いての病態再現2012
- Author(s)
  庄子栄美、櫻井英俊
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡マリンメッセ
- Data Source
  KAKENHI-PROJECT-24790383
[Presentation] Modelling Duchenne muscular dystrophy (DMD) with human induced pluripotent stem cells2012
- Author(s)
  Emi Shoji, Hidetoshi Sakurai
- Organizer
  第7回研究所ネットワーク国際シンポジウム
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-24790383
[Presentation] 転写因子を用いた効率的なヒトiPS細胞からの骨格筋細胞誘導法の確立2011
- Author(s)
  田中章仁、櫻井英俊
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22790284
[Presentation] iPS細胞からの中胚葉前駆細胞誘導と、細胞移植治療に向けた研究開発2010
- Author(s)
  櫻井英俊
- Organizer
  筋ジストロフィーに対するトランスレーショナル・リサーチ
- Place of Presentation
  東京
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-22790284
[Presentation] Transplantation of mouse iPS cell-derived mesodermal progenitors improves structure and function of skeletal muscle in Duchenne Muscular Dystrophy model mice2010
- Author(s)
  櫻井英俊
- Organizer
  The 8^<th> Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Moscone West(サンフランシスコ)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22790284
[Presentation] Transplantation of mouse iPS cell-derived mesodermal progenitors improves structure and function of skeletal muscle in Duchenne Muscular Dystrophy model mice2010
- Author(s)
  櫻井英俊
- Organizer
  8th International Society for Stem Cell Research Annual Meeting
- Place of Presentation
  トロント(カナダ)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22790284

1. TAKAHASHI Kazutoshi (80432326)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. EBIHARA Ken (70362514)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. NOGUCHI Michio (00432394)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SONE Masakatsu (40437207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. HOSODA Kiminori (40271598)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. YAMASHITA Jun (50335288)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NAKAO Kazuki (20217657)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Ikeya Makoto (20442923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. TOGUCHIDA Junya (40273502)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MATSUO Masafumi (10157266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. AWAYA Tomonari (20589593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKAHASHI Masanori (20359847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. NAKAMORI Masayuki (60630233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. WATANABE Akira (60506765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KIN Eiki (90620344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUJIKURA Junji (70378743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Imamura Takeshi (00552093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. TAWA Masashi (10510274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 森野勝太郎 (90444447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. UEKI Junko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. Jonouchi Tatsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. IWASAKI Hirotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 戸田口淳也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 中尾一和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 森潔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 稲垣暢也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakurai Hidetoshi 櫻井 英俊

櫻井 英俊 サクライ ヒデトシ

SAKURAI Hidetoshi 櫻井 英俊

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of skeletal muscle regeneration utilizing iPSC-derived mesenchymal stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell therapy for Pompe disease using iPSC-derived muscle stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of free fatty acid receptors on the differentiation of human skeletal myogenesis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instabilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Derivation of human PSC-derived mesodermal cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of fibrodysplasia ossificans progressive by using iPSCs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel therapy for lipodystrophy and obesity using human iPS cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of pathogenesis and development of therapy of lipodystrophy using human iPS cell-derived adipocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell therapy of adipocytes derived from human iPS cells using cellcontainers and animal disease models

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modeling Duchenne muscular dystrophy using patient-derived iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell therapy for Muscular Dystrophy using myogenic progenitor cells derived from human iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis in human induced pluripotent stem cells.2015

Author(s)

Journal Title

Sakurai Hidetoshi 櫻井英俊

櫻井英俊サクライヒデトシ

SAKURAI Hidetoshi 櫻井英俊

[Presentation] Ullrich型先天性筋ジストロフィーの病態改善を目指した細胞移植治療法の確立～移植用細胞源検討～2024