HAMAZAKI Jun 濱崎純

Researcher Number	80533588
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院薬学系研究科(薬学部), 講師
Affiliation (based on the past Project Information) *help	2023: 東京大学, 大学院薬学系研究科(薬学部), 講師 2016 – 2022: 東京大学, 大学院薬学系研究科(薬学部), 助教 2012 – 2015: 東京大学, 薬学研究科(研究院), 助教 2009 – 2011: The University of Tokyo, 大学院・薬学系研究科, 助教
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological Sciences Except Principal Investigator Biological Sciences
Keywords	Principal Investigator プロテアソーム / ユビキチン / タンパク質分解 / 分子生物学 / O-GlcNAc / 酸化ストレス / 神経変性疾患 / ショウジョウバエ / 分生生物学 Except Principal Investigator ヘムオキシゲナーゼ１ … More / 転写因子 / プロテオスタシス / ATF4 / GCN1L1 / 酸化ストレス / eIF2alpha / 酸素ストレス / 活性酸素 / プロテアソーム / ミトコンドリア / Keap1 / Nrf2 Less

プロテアソーム不全に応答する新たなプロテアソーム機能維持機構の解明Principal Investigator
- Principal Investigator
  
  濱崎純
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Elucidation of a novel homeostatic mechanism by enhanced O-GlcNAcylation under proteasome dysfunctionPrincipal Investigator
- Principal Investigator
  
  Hamazaki Jun
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokyo
Analysis of the mechanism of the degradation of aggregation prone proteiins by a novel ubiquitin binding protein CG5445Principal Investigator
- Principal Investigator
  
  Hamazaki Jun
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Elucidation of redox regulatory mechanisms by transcription factor network
- Principal Investigator
  
  Itoh Ken
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Analysis of the mechanism of the regulation of proteasome by novel modifier PI31Principal Investigator
- Principal Investigator
  
  HAMAZAKI Jun
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
酸化ストレスにおけるプロテアソームの動態制御機構についての解析Principal Investigator
- Principal Investigator
  
  濱崎純
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
酸化ストレスにおけるプロテアソームの動態制御機構についての解析Principal Investigator
- Principal Investigator
  
  濱崎純
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Exploration of novel proteasome modulating proteins by using Drosophila melanogasterPrincipal Investigator
- Principal Investigator
  
  HAMAZAKI Jun
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

[Book] 医学のあゆみ、活性酸素・基礎から病態解明・制御まで2013
- Author(s)
  濱崎純、村田茂穂
- Total Pages
  6
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-24590075
[Book] 実験医学増刊　活性酸素・ガス状分子による恒常性制御と疾患2013
- Author(s)
  濱崎　純、村田　茂穂
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24590075
[Book] 活性酸素・ガス状分子による恒常性制御と疾患2012
- Author(s)
  濱崎　純
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-23117706
[Journal Article] Senescent cells form nuclear foci that contain the 26S proteasome2023
- Author(s)
  Iriki Tomohiro、Iio Hiroaki、Yasuda Shu、Masuta Shun、Kato Masakazu、Kosako Hidetaka、Hirayama Shoshiro、Endo Akinori、Ohtake Fumiaki、Kamiya Mako、Urano Yasuteru、Saeki Yasushi、Hamazaki Jun、Murata Shigeo
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 112880-112880
- DOI
  10.1016/j.celrep.2023.112880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18107, KAKENHI-PROJECT-22K06611, KAKENHI-WRAPUP-23H05424, KAKENHI-ORGANIZER-23H04917, KAKENHI-PLANNED-23H04918, KAKENHI-PLANNED-23H04921, KAKENHI-PROJECT-23H05479, KAKENHI-PROJECT-22H00402
[Journal Article] PAC1 deficiency protects obese male mice from immobilization-induced muscle atrophy by suppressing FoxO-atrogene axis2023
- Author(s)
  Li Qifang、Ishii Kiyo-aki、Kamoshita Kyoko、Takahashi Kenta、Abuduwaili Halimulati、Takayama Hiroaki、Galicia-Medina Cynthia M、Tanida Ryota、Oo Hein Ko、Gafiyatullina Guzel、Yao Xingyu、Abuduyimiti Tuerdiguli、Hamazaki Jun、Harada Kenichi、Murata Shigeo、Takamura Toshinari
- Journal Title
  
  Endocrinology
  
  Volume: - Issue: 6 Pages: 164-165
- DOI
  10.1210/endocr/bqad065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-23K18107, KAKENHI-PROJECT-23KF0035, KAKENHI-PROJECT-22K06611, KAKENHI-PROJECT-23K08004, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-21K19503, KAKENHI-PLANNED-23H04918, KAKENHI-PROJECT-22H00402, KAKENHI-PROJECT-23K27649
[Journal Article] Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency2021
- Author(s)
  Kanazawa N, Hemmi H, Kinjo N, Ohnishi H, Hamazaki J, M.H, K.A, M.T, H.S, K.N, K.S, H.Y, I.K, N.R, T.M, Y.Y, T.S, O.T, O.T, K.T, S.I, F.Y, W.N, I.Y, K.K, O.S, T.T, N.K, M.S, Y.K, Kaisho T
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 0-0
- DOI
  10.1038/s41467-021-27085-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-19K08299, KAKENHI-PROJECT-20K16289, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-19H03620, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-20H03591, KAKENHI-PROJECT-21J22615, KAKENHI-PROJECT-19K08754, KAKENHI-PROJECT-19K08798, KAKENHI-PROJECT-19K09993, KAKENHI-PROJECT-20K08158, KAKENHI-PROJECT-20K08718, KAKENHI-PROJECT-21K06956, KAKENHI-PROJECT-21K07770, KAKENHI-PROJECT-21K07800, KAKENHI-PROJECT-21K19384, KAKENHI-PROJECT-20K17405
[Journal Article] NRF3-POMP-20S proteasome assembly axis promotes cancer development via ubiquitin-independent proteolysis of p53 and Rb.2020
- Author(s)
  Waku T, Nakamura N, Koji M, Watanabe H, Katoh H, Tatsumi C, Tamura N, Hatanaka A, Hirose S, Katayama H, Tani M, Kubo Y, Hamazaki J, Hamakubo T, Watanabe A, Murata S, Kobayashi A
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: - Issue: 10 Pages: 1-1
- DOI
  10.1128/mcb.00597-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-18J20672, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-20H04135, KAKENHI-ORGANIZER-18H05497
[Journal Article] Enhanced O-GlcNAcylation Mediates Cytoprotection under Proteasome Impairment by Promoting Proteasome Turnover in Cancer Cells2020
- Author(s)
  Hashimoto E, Okuno S, Hirayama S, Arata Y, Goto T, Kosako H, Hamazaki J, Murata S.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 7 Pages: 101299-101299
- DOI
  10.1016/j.isci.2020.101299
- NAID
  120007127449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-ORGANIZER-18H05497
[Journal Article] ER-Resident Transcription Factor Nrf1 Regulates Proteasome Expression and Beyond2020
- Author(s)
  Hamazaki J, Murata S.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 10 Pages: 3683-3683
- DOI
  10.3390/ijms21103683
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PLANNED-18H05500
[Journal Article] Recognition and degradation of ubiquitinated proteins by the 26S proteasome2020
- Author(s)
  濱崎　純、村田　茂穂
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 48-56
- DOI
  10.14952/SEIKAGAKU.2020.920048
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-ORGANIZER-18H05497
[Journal Article] Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence2019
- Author(s)
  Arata Y, Watanabe A, Motosugi R, Murakami R, Goto T, Hori S, Hirayama S, Hamazaki J, Murata S.
- Journal Title
  
  Genes Cells
  
  Volume: 24 Issue: 12 Pages: 801-813
- DOI
  10.1111/gtc.12728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-19K22526, KAKENHI-PLANNED-18H05500, KAKENHI-PUBLICLY-19H04801, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-18H04025, KAKENHI-PROJECT-19K16601
[Journal Article] FAM48A mediates compensatory autophagy induced by proteasome impairment.2019
- Author(s)
  Arata Y, Watanabe A, Motosugi R, Iemura SI, Natsume T, Mukai K, Taguchi T, Hirayama S, Hamazaki J, Murata S.
- Journal Title
  
  Genes Cells
  
  Volume: 24 Issue: 8 Pages: 559-568
- DOI
  10.1111/gtc.12708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-17H06418, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-17K15445, KAKENHI-PROJECT-17H06164, KAKENHI-PLANNED-15H05903
[Journal Article] Trans-omics impact of thymoproteasome in cortical thymic epithelial cells.2019
- Author(s)
  Ohigashi I, Tanaka Y, Kondo K, Fujimori S, Kondo H, Palin A, Hoffmann V, Kozai M, Matsushita Y, Uda S, Motosugi R, Hamazaki J, Kubota H, Murata S, Tanaka K, Katagiri T, Kosako H, Takahama Y
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 9 Pages: 2901-2916
- DOI
  10.1016/j.celrep.2019.10.079
- NAID
  120006894616
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04801, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18H02431, KAKENHI-PROJECT-17K08884, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-16H06577
[Journal Article] Shigella effector IpaH4.5 targets 19S regulatory subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation.2019
- Author(s)
  Otsubo R, Mimura H, Ashida H, Hamazaki J, Murata S, Sasakawa C.
- Journal Title
  
  Cell Microbiol.
  
  Volume: 21 Issue: 3 Pages: e12974-e12974
- DOI
  10.1111/cmi.12974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-17K19551, KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-16H05186, KAKENHI-PROJECT-26000014
[Journal Article] Transcriptional regulation of the 26S proteasome by Nrf12018
- Author(s)
  Koizumi S, Hamazaki J, Murata S.
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 94 Issue: 8 Pages: 325-336
- DOI
  10.2183/pjab.94.021
- NAID
  130007497652
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2018-10-11
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] PAC1-PAC2 proteasome assembly chaperone retains the core α4-α7 assembly intermediates in the cytoplasm.2018
- Author(s)
  Wu W, Sahara K, Hirayama S, Zhao X, Watanabe A, Hamazaki J, Yashiroda H, Murata S.
- Journal Title
  
  Gene to Cells
  
  Volume: 10 Issue: 10 Pages: 839-848
- DOI
  10.1111/gtc.12631
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K07342, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Specific modification of aged proteasomes revealed by tag-exchangeable knock-in mice.2018
- Author(s)
  Tomita, T., Hirayama, S., Sakurai, Y., Ohte, Y., Yoshihara, H., Saeki, Y., Hamazaki, J., and Murata, S.
- Journal Title
  
  Mol. Cell Biol.
  
  Volume: 39 Issue: 1
- DOI
  10.1128/mcb.00426-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Early and consistent overexpression of ADRM1 in ovarian high-grade serous cartinoma.2017
- Author(s)
  Jiang RT, Yemelyanova A, Xing D, Anchoori RK, Hamazaki J, Murata S, Seidman JD, Wang TL, Roden RBS.
- Journal Title
  
  Jounal of Ovarian Research
  
  Volume: 10 Issue: 1 Pages: 53-53
- DOI
  10.1186/s13048-017-0347-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-26000014
[Journal Article] Foxn1-β5t transcriptional axis controls CD8+ T cell production in the thymus.2017
- Author(s)
  Uddin MM, Ohigashi I, Motosugi R, Nakayama T, Sakata M, Hamazaki J, Nishito Y, Rode I, Tanaka K, Takemoto T, Murata S, Takahama Y.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 14419-14419
- DOI
  10.1038/ncomms14419
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-15K19130, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-26000014
[Journal Article] Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.2017
- Author(s)
  Lu X, Nowicka U, Sridharan V, Liu F, Ramdles L, Hymel D, Dyba M, Tarasov SG, Tarasova NI, Zhao XZ, Hamazaki J, Murata S, Burke TR Jr, Walters KJ.
- Journal Title
  
  nature communications
  
  Volume: 8 Issue: 1 Pages: 15540-15540
- DOI
  10.1038/ncomms15540
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-26000014
[Journal Article] Ubiquitin-Binding Protein CG5445 Suppresses Aggregation and Cytotoxicity of Amyotrophic Lateral Sclerosis-linked TDP-43 in Drosophila.2017
- Author(s)
  Uechi H, Kuranaga E, Iriki T, Takano K, Hirayama S, Miura M, Hamazaki J, Murata S.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 3 Issue: 3
- DOI
  10.1128/mcb.00195-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-17K19884, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-16K20998, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.2016
- Author(s)
  Koizumi S, Irie T, Hirayama S, Sakurai Y, Yashiroda H, Naguro I, Ichijo H, Hamazaki J, Murata S.
- Journal Title
  
  Elife
  
  Volume: 18357 Pages: 18357-18357
- DOI
  10.7554/elife.18357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15J01930, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-16K20998, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-26114009
[Journal Article] Redundant roles of Rpn10 and Rpn13 in recognition of ubiquitinated proteins and cellular homeostasis.2015
- Author(s)
  Hamazaki J, Hirayama S, Murata S. Redundant roles of Rpn10 and Rpn13 in recognition of ubiquitinated proteins and cellular homeostasis.
- Journal Title
  
  PLoS Genet.
  
  Volume: 11 Issue: 7 Pages: e1005401-e1005401
- DOI
  10.1371/journal.pgen.1005401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PUBLICLY-26111704, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Characterization of Testis-Specific Proteasome Subunit α4s in Mammals2014
- Author(s)
  Hiroyuki Uechi, Jun Hamazaki, and Shigeo Murata
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 18 Pages: 12365-12374
- DOI
  10.1074/jbc.m114.558866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10397, KAKENHI-PROJECT-24590075, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-26111010
[Journal Article] Mouse zygote-specific proteasome assembly chaperone important for maternal-to-zygotic transition2013
- Author(s)
  Shin SW
- Journal Title
  
  Biolology Open
  
  Volume: 2 Issue: 2 Pages: 170-182
- DOI
  10.1242/bio.20123020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380164, KAKENHI-PROJECT-23500506, KAKENHI-PROJECT-23657083, KAKENHI-PROJECT-23658292, KAKENHI-PROJECT-24590075, KAKENHI-PUBLICLY-23117706
[Journal Article] PAC1 gene knockout reveals an essential role of chaperon-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.2010
- Author(s)
  Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S.
- Journal Title
  
  Molecular Cellular Biology 30(15)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790064
[Journal Article] Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperon.2009
- Author(s)
  Kaneko T, Hamazaki J, Iemura S, Sasaki K, Furuyama K, Natsume T, Tanaka K, Murata S.
- Journal Title
  
  Cell 137(5)
  
  Pages: 914-925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790064
[Journal Article] Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain.2009
- Author(s)
  Nishio K, Kim SW, Kawai K, Mizushima T, Yamane T, Hamazaki J, Murata S, Tanaka K, Morimoto Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications 390(3)
  
  Pages: 855-860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790064
[Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved ptoteasome function in an SBMA model mouse.2009
- Author(s)
  Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
- Journal Title
  
  Human Molecular Genetics 18(5)
  
  Pages: 898-910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790064
[Journal Article] Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process.2009
- Author(s)
  Tonoki A, Kuranaga E, Tomioka T, Hamazaki J, Murata S, Tanaka K, Miura M.
- Journal Title
  
  Molecular Cellular Biology 29(4)
  
  Pages: 106-1095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790064
[Presentation] 哺乳類プロテアソームの新規転写因子の同定2023
- Author(s)
  橋本創太、王妍、董瑶加、平山尚志郎、濱崎純、村田茂穂
- Organizer
  第96回生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06611
[Presentation] 細胞老化に伴う新規プロテアソーム核内fociの形成によるミトコンドリア活性の抑制2023
- Author(s)
  濱崎純、村田茂穂
- Organizer
  第75回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06611
[Presentation] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity under proteasome impairment2023
- Author(s)
  Jun Kishiki, Shota Okuno, Eiichi Hashimoto, Shoshiro Hirayama, Hidetaka Kosako, Jun Hamazaki, and Shigeo Murata
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06611
[Presentation] プロテアソーム活性を指標にしたCRISPRスクリーニングによる哺乳類プロテアソームの機能制御因子の網羅的探索2023
- Author(s)
  稲見真紀, 川邉明広, 平山尚志郎, 榎本豊, 北村俊雄, 濱崎純, 村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06611
[Presentation] 細胞老化に伴う新規プロテアソーム核内foci SANPs(senescence-associated nuclear proteasome foci）の発見2023
- Author(s)
  飯尾浩章、入木朋洋、安田柊、増田竣、加藤雅和、小迫英尊、平山尚志郎、遠藤彬則、大竹史明、神谷真子、浦野泰照、佐伯泰、濱崎純、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06611
[Presentation] ユビキチン・プロテアソーム系の不調による炎症性疾患発症の分子機構2022
- Author(s)
  濱崎純、村田茂穂
- Organizer
  第5回日本免疫不全・自己炎症学会　総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] プロテアソーム活性を指標にしたCRISPRスクリーニングによる哺乳類プロテアソーム機能制御因子の網羅的探索2022
- Author(s)
  川邉明広, 濱崎純, 村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06611
[Presentation] DDI2過剰発現によるプロテアソーム活性亢進マウスにおけるタンパク質恒常性への影響の解析2022
- Author(s)
  加藤雅和、濱崎純、村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06611
[Presentation] 哺乳類プロテアソームの基礎的発現制御因子の探索2021
- Author(s)
  山村まどか、本杉良、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] Senescence-associated nuclear proteasome foci degrade p21 and suppress mitochondrial activation2021
- Author(s)
  増田竣, 入木朋洋, 安田柊, 小迫英尊, 平山尚志郎, 大竹史明, 佐伯泰, 濱崎純, 村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] ユビキチンリガーゼRNF181はプロテアソーム機能低下時のプロテアソーム活性維持に重要な役割を果たす2021
- Author(s)
  吉敷純、平山尚志郎、小迫英尊、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] プロテアソーム転写因子Nrf1活性化に働く新規プロテアーゼDDI2によるプロセシング条件の検討2021
- Author(s)
  下岡雅和、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] 細胞老化依存的に生じるプロテアソームfociの機能解析2020
- Author(s)
  安田柊、入木朋洋、増田竣、平山尚志郎、濱崎純、村田茂穂
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity unde proteasome impairment.2020
- Author(s)
  Shota Okuno, Eiichi Hashimoto, Shoshiro Hirayama, Hidetaka Kosako, Jun Hamazaki, and Shigeo Murata
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] RNF181 plays a pivotal role in O-GlcNAcylation-mediated cytoprotection under the proteasome impairment in canser cells2019
- Author(s)
  Jun Hamazaki, Eiichi Hashimoto, Shota Okuno, Shohiro Hirayama, Hidetaka Kosako, Shigeo Murata
- Organizer
  3rd EMBO Conferense Series, The ubiquitin system
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07062
[Presentation] プロテアソーム不全時のO-GlcNAc修飾亢進による新規恒常性維持機構2019
- Author(s)
  濱崎純
- Organizer
  第1回新学術「ケモユビキチン」班会議・第2回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] 精子形成過程におけるプロテアソーム相互作用因子PI31の機能解明2019
- Author(s)
  福島聡真、入木朋洋、濱崎純、村田茂穂
- Organizer
  第1回新学術「ケモユビキチン」班会議・第2回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソーム機能低下時に代償的に働く機構の網羅的探索2019
- Author(s)
  橋本永一、濱崎純、村田茂穂
- Organizer
  第1回新学術「ケモユビキチン」班会議・第2回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソーム不調と細胞恒常性維持2019
- Author(s)
  濱崎純
- Organizer
  第3回Fibrosis
- Invited
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] ヒト全ゲノムスクリーニングによる哺乳類プロテアソーム機能制御因子の同定2018
- Author(s)
  董瑶加、馬籠耕平、橋本永一、濱崎純、村田茂穂
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] 哺乳類プロテアソームの細胞内局在はmTOR経路により制御される2018
- Author(s)
  松浦昌太郎、濱崎純、平山尚志郎、村田茂穂
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] The mechanism of cellular senescence induced by proteasome dysfunction2017
- Author(s)
  Tomohiro Iriki, Eiichi Hasimoto, Shoshiro Hirayama, Jun Hamazaki, Shigeo Murata
- Organizer
  Graduate Programme in Leaders in Life Innovation Joint Symposium with University of Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] The mechanism of cellular senescence induced by proteasome dysfunction2017
- Author(s)
  Tomohiro Iriki, Eiichi Hasimoto, Shoshiro Hirayama, Jun Hamazaki, Shigeo Murata
- Organizer
  CIMR UTokyo Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] The mechanism of cellular senescence induced by proteasome dysfunction2017
- Author(s)
  Tomohiro Iriki, Eiichi Hasimoto, Shoshiro Hirayama, Jun Hamazaki, Shigeo Murata
- Organizer
  KCL-Institute of Psychiatry, Psychology & Neuroscience UT-GIPLLI Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] The Glycolytic pathway is required for cell survival under modest proteasome impairment2017
- Author(s)
  橋本永一、濱崎純、村田茂穂
- Organizer
  東京大学-同志社大学リトリート
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] The mechanism of cellular senescence induced by proteasome dysfunction2017
- Author(s)
  Tomohiro Iriki, Eiichi Hasimoto, Shoshiro Hirayama, Jun Hamazaki, Shigeo Murata
- Organizer
  CIMR-UTokyo Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Genome-wide siRNA screening for factors maintaining cellular homeostasis under proteasome inhibition2017
- Author(s)
  橋本永一、濱崎純、村田茂穂
- Organizer
  第3回4大学1研合同研究会
- Place of Presentation
  秋保リゾートホテルクレセント(宮城県仙台市)
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソーム発現制御転写因子Nrf1の活性化機構2017
- Author(s)
  小泉峻、濱崎純、村田茂穂
- Organizer
  2017年度生命科学系学会合同年次大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] The mechanism of cellular senescence induced by proteasome dysfunction2017
- Author(s)
  Tomohiro Iriki, Eiichi Hasimoto, Shoshiro Hirayama, Jun Hamazaki, Shigeo Murata
- Organizer
  Stockholm-Tokyo University Partnership, Living longer and healthier in an ageing world
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] The Glycolytic pathway is required for cell survival under modest proteasome impairment2017
- Author(s)
  橋本永一、濱崎純、村田茂穂
- Organizer
  第17回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソーム発現制御転写因子Nrf1の活性化機構2017
- Author(s)
  小泉峻、濱崎純、村田茂穂
- Organizer
  東京大学-同志社大学リトリート
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] Identification of the mechanism for Nrf1 activation in response to proteasome inhibition2017
- Author(s)
  小泉峻、濱崎純、村田茂穂
- Organizer
  第3回4大学1研合同研究会
- Place of Presentation
  秋保リゾートホテルクレセント(宮城県仙台市)
- Year and Date
  2017-01-07
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] In vivo analysis of the proteasome inhibitor protein PI312017
- Author(s)
  入木朋洋、上地浩之、濱崎純、村田茂穂
- Organizer
  CIMR Grad Sch Pharm in Utokyo Workshop/Retreat program
- Place of Presentation
  小田急山のホテル（神奈川県箱根町
- Year and Date
  2017-01-31
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソーム機能低下による細胞老化誘導機構の解明2017
- Author(s)
  入木朋洋、橋本永一、平山尚志郎、濱崎純、村田茂穂
- Organizer
  東京大学-同志社大学リトリート
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソーム転写因子Nrf1活性化に働く新規プロテアーゼDDI2阻害剤探索2017
- Author(s)
  高野滉平、小泉峻、濱崎純、村田茂穂
- Organizer
  2017年度生命科学系学会合同年次大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] Nrf1活性化に働く新規プロテアーゼDDI2阻害剤スクリーニング2017
- Author(s)
  高野滉平、小泉峻、平山尚志郎、濱崎純、村田茂穂
- Organizer
  東京大学-同志社大学リトリート
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソームと酸化ストレスのクロストークの解析2016
- Author(s)
  濱崎　純
- Organizer
  第3回新学術領域研究「酸素生物学」全体班会議
- Place of Presentation
  東京大学弥生講堂一条ホール（東京都文京区）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] Identification of the mechanism for Nrf1 activation in response to proteasome inhibition2016
- Author(s)
  小泉峻、入江太郎、濱崎純、村田茂穂
- Organizer
  第16回東京大学生命科学シンポジウム
- Place of Presentation
  東京大学駒場キャンパス 21 Komcee (東京都目黒区)
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] Uncovering the mechanism for maintaining cellular homeostasis under proteasome inhibition2016
- Author(s)
  Eiichi Hashimoto、Jun Hamazaki、Shigeo Murata
- Organizer
  3rd PROTEOSTASIS Action Meeting
- Place of Presentation
  Lisbon (Portugal)
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] In vivo analysis of the proteasome inhibitor protein PI312016
- Author(s)
  入木朋洋、上地浩之、濱崎純、村田茂穂
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜国際平和会議場（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] 哺乳類プロテアソームにおける基質認識と分解調節機構2016
- Author(s)
  濱崎　純
- Organizer
  第11回レドックス・ライフイノベーションシンポジウム
- Place of Presentation
  お茶の水女子大学（東京都文京区）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Identification of the mechanism for Nrf1 activation in response to proteasome inhibition2016
- Author(s)
  Shun Koizumi, Jun Hamazaki, Shigeo Murata
- Organizer
  3rd PROTEOSTASIS Action Meeting Proteostasis and its Biological Implications
- Place of Presentation
  Lisbon (Portugal)
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] 胸腺皮質特異的プロテアソームサブユニットβ5tの転写因子の同定2016
- Author(s)
  本杉良、濱崎純、西籐泰昌、高浜洋介、村田茂穂
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜国際平和会議場（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] ヒト全ゲノムスクリーニングによるプロテアソーム機能制御因子の同定2016
- Author(s)
  馬籠耕平、橋本永一、濱崎純、村田茂穂
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜国際平和会議場 (神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] プロテアソーム活性低下時に生じる転写因子Nrf1の活性化機構の解明2016
- Author(s)
  小泉峻、濱崎純、村田茂穂
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜国際平和会議場（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08228
[Presentation] Testis-specific proteasome and its role in mammalian testes2013
- Author(s)
  Hiroyuki Uechi, Jun Hamazaki, Shigeo Murata
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川、横浜
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] プロテアソーム会合チオレドキシン様分子のメラニン産生への関与2013
- Author(s)
  上地浩之、濱崎純、村田茂穂
- Organizer
  新学術領域研究　ユビキチンネオバイオロジー　平成25年度第2回領域班会議
- Place of Presentation
  静岡、熱海
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Transcriptional Modulators of the Mammalian 26S Proteasome – _A Genome-wide Perspective2013
- Author(s)
  Kogleck Larissa, Hirayama Shoshiro, Hamazaki Jun, Murata Shigeo
- Organizer
  東京大学生命科学シンポジウム
- Place of Presentation
  東京、本郷
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Genetic analysis of novel mammalian protesasome subunit Rpn132013
- Author(s)
  Jun Hamazaki, Shigeo Murata
- Organizer
  The 35th NAITO CONFERENCE ON The Ubiquitin-Proteasome System
- Place of Presentation
  北海道、札幌
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Sirt1によるHsp70を介したタンパク質品質管理2013
- Author(s)
  冨田拓哉、濱崎純、平山尚志郎、八代田英樹、村田茂穂
- Organizer
  新学術領域研究　ユビキチンネオバイオロジー　平成25年度第2回領域班会議
- Place of Presentation
  静岡、熱海
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Functional Analysis of PI312013
- Author(s)
  Haruta Yoshitaro, Hamazaki Jun, Murata Shigeo
- Organizer
  東京大学生命科学シンポジウム
- Place of Presentation
  東京、本郷
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Genetic analysis of the ubiquitin receptor subunit of the proteasome, Rpn13 in mice2012
- Author(s)
  Jun Hamazaki
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23117706
[Presentation] A genome-wide approach to identify the regulatory mechanisms of mammalian 26S proteaome gene transcription2012
- Author(s)
  Larissa Kogleck, Jun Hamazaki, Shigeo Murata
- Organizer
  FEBS Special Meeting on Protein Quality Control and Ubiquitin Proteasome System in Health and Disease
- Place of Presentation
  Izmir (Turkey)
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Genetic analysis of novel mammalian proteasome subunit Rpn132012
- Author(s)
  Jun Hamazaki
- Organizer
  FEBS special meeting on Protein Quality Control and Ubiquitin Proteasome System in Health and Disease
- Place of Presentation
  Izmir (Turkey)
- Year and Date
  2012-11-14
- Data Source
  KAKENHI-PUBLICLY-23117706
[Presentation] Genetic analysis of novel mammalian proteasome subunit Rpn132012
- Author(s)
  Jun Hamazaki, Shigeo Murata
- Organizer
  FEBS Special Meeting on Protein Quality Control and Ubiquitin Proteasome System in Health and Disease
- Place of Presentation
  Izmir (Turkey)
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Functional analysis of PI31
- Author(s)
  Takaya Ishii, Jun Hamazaki, Shigeo Murata
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Collaborative roles of proteasome ubiquitin receptors Rpn13 and Rpn10 are essential for hepatocyte homeostasis
- Author(s)
  Jun Hamazaki, Shigeo Murata
- Organizer
  FASEB Science Research Conferences 2014 Ubiquitin and Cellular Regulation
- Place of Presentation
  Saxton River, Vermont, USA
- Year and Date
  2014-06-15 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Investigation of the biological meaning of b subunit diversity
- Author(s)
  Akihito Fukuda, Jun Hamazaki, Shigeo Murata
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] 哺乳類プロテアソームにおけるユビキチン化タンパク質認識機構と脱ユビキチン化機構の遺伝学的解析
- Author(s)
  濱崎純、村田茂穂
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Enzymatic purification and mass spectrometric identification of polyubiquitinated proteins
- Author(s)
  Naoyuki Mita, Kiyo Shimada, Takeumi Kaneko, Jun Hamazaki, Shigeo Murata
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Regulationo fo the ubiquitin-proteasome system by Sirt1
- Author(s)
  Takuya Tomita, Jun Hamazaki, Hideki Yashiroda, Shigeo Murata
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] A heat shock proteins- and ubiquitin-interacting protein counteracts aggregate formation of ubiquitinated proteins for proteasome degradation
- Author(s)
  Hiroyuki Uechi, Jun Hamazaki, Erina Kuranaga, Masayuki Miura, and Shigeo Murata
- Organizer
  Symposium for young ubiquitin researchers in Japan "New Era in the Ubiquitin Research"
- Place of Presentation
  国際高等研究所 (京都)
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] Genetic analysis of the ubiquitin receptor subunit of the proteasome, Rpn13 in mice
- Author(s)
  Jun Hamazaki, Shigeo Murata
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] 哺乳類プロテアソームにおけるユビキチン化タンパク質認識機構と脱ユビキチン化機構の遺伝学的解析
- Author(s)
  濱崎純、村田茂穂.
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] プロテアソーム相互作用因子PI31の機能解析
- Author(s)
  治田義太郎、濱崎純、八代田英樹、村田茂穂
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] A novel ubiquitin-interacting protein that counteracts aggregate formation of ubiquitinated proteins
- Author(s)
  Hiroyuki Uechi, Jun Hamazaki, Erina Kuranaga, Masayuki Miura, and Shigeo Murata
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都 (京都)
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590075
[Presentation] 哺乳類プロテアソームサブユニットRpn10とRpn13による協調したユビキチン認識はプロテアソーム機能に重要である
- Author(s)
  濱崎純、村田茂穂
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24590075

1. Itoh Ken (10323289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 鈴木隆史 (70508308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SAEKI Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. ISHII Kiyoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 高浜洋介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 村田茂穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

HAMAZAKI Jun 濱崎 純

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プロテアソーム不全に応答する新たなプロテアソーム機能維持機構の解明Principal Investigator

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Elucidation of a novel homeostatic mechanism by enhanced O-GlcNAcylation under proteasome dysfunctionPrincipal Investigator

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Analysis of the mechanism of the degradation of aggregation prone proteiins by a novel ubiquitin binding protein CG5445Principal Investigator

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Elucidation of redox regulatory mechanisms by transcription factor network

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Analysis of the mechanism of the regulation of proteasome by novel modifier PI31Principal Investigator

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酸化ストレスにおけるプロテアソームの動態制御機構についての解析Principal Investigator

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酸化ストレスにおけるプロテアソームの動態制御機構についての解析Principal Investigator

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Exploration of novel proteasome modulating proteins by using Drosophila melanogasterPrincipal Investigator

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[Book] 医学のあゆみ、活性酸素・基礎から病態解明・制御まで2013

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[Book] 実験医学増刊 活性酸素・ガス状分子による恒常性制御と疾患2013

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[Book] 活性酸素・ガス状分子による恒常性制御と疾患2012

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[Journal Article] Senescent cells form nuclear foci that contain the 26S proteasome2023

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[Journal Article] PAC1 deficiency protects obese male mice from immobilization-induced muscle atrophy by suppressing FoxO-atrogene axis2023

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[Journal Article] Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency2021

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HAMAZAKI Jun 濱崎純

[Book] 実験医学増刊　活性酸素・ガス状分子による恒常性制御と疾患2013