arashiki nobuto 新敷信人

… Alternative Names

新敷信人アラシキノブト

ARASHIKI Nobuto 新敷信人

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Researcher Number	80569658
Other IDs
Affiliation (Current)	2025: 東京女子医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2018 – 2023: 東京女子医科大学, 医学部, 助教 2012 – 2016: 東京女子医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related Except Principal Investigator Infectious disease medicine / Basic Section 54030:Infectious disease medicine-related / General medical chemistry
Keywords	Principal Investigator 神経発達 / 脂質非対称性崩壊 / 細胞膜 / セマフォリン3A / 神経突起伸長退縮 / PS表在化に至るおおよそのシグナル経路解明 / Sema3A受容体の絞り込み / 樹状突起発達 / カスパーゼ活性化 / PlexinA1~A4の発現局在 / ホスファチジルセリン表在化 / 神経ガイダンス因子セマフォリン3A / 大脳皮質初代神経細胞 … More Except Principal Investigator … More PKAリン酸化 / マラリア原虫 / 赤血球 / マラリア / ATP受容体 / 感染防御 / 情報伝達 / cAMP / デマチン / 赤血球膜骨格 / ATP / プリンヌクレオチド受容体 / リン酸化 / 膜蛋白質 / 非対称性分布 / リン脂質 / 抑制効果 / 多量体形成 / 赤血球膜 / スクランブリング抑制効果 / 赤血球寿命 / 溶血性貧血 / リン脂質輸送メカニズム / PLSCR1 / リン脂質スクランブリング / フリッパーゼ / スクランブラーゼ / コレステロール / ヒト赤血球膜 / Eat me signal / フォスファチジルセリン / リン脂質非対称性 / G蛋白質共役受容体 / シグナル伝達 / 感染症 / 抗感染症薬 / Feline immunodeficiency virus / Plasmodium falciparum / リドカイン / 脂質ラフト Less

An identification of the signaling pathway involving in Sema3A-induced breakdown of the asymmetric distribution in the developing neuron's membranePrincipal Investigator
- Principal Investigator
  
  新敷信人
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tokyo Women's Medical University
Role of purine nucleotide receptor signaling in P. falciparum invasion of erythrocytes.
- Principal Investigator
  
  Koshino Ichiro
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Tokyo Women's Medical University
Studies on PKA phosphorylation events in host red cells during invasion by Plasmodium falciparum
- Principal Investigator
  
  Koshino Ichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Tokyo Women's Medical University
An inhibitory effect of cholesterol on expressing eat me signals in human erythrocyte membrane
- Principal Investigator
  
  Takakuwa Yuichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Women's Medical University
Exploration of a novel role for lidocaine as a wide range spectrum anti-infection drug
- Principal Investigator
  
  TAKAKUWA Yuichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Tokyo Women's Medical University

All 2023 2022 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia.2016
- Author(s)
  Nobuto Arashiki, Yuichi Takakuwa, Hitoshi Kanno
- Journal Title
  
  Haematologica
  
  Volume: 印刷中 Issue: 5 Pages: 559-565
- DOI
  10.3324/haematol.2016.142273
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460375, KAKENHI-PROJECT-25461609, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308
[Journal Article] ヒト赤血球の寿命を規定するメカニズム2014
- Author(s)
  高桑雄一、新敷信人、斎藤将樹
- Journal Title
  
  臨床血液
  
  Volume: 55 Pages: 643-643
- NAID
  130004501864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460375
[Journal Article] Membrane peroxidation and methemoglobin formation are both necessary for band 3 clustering: mechanistic insights into human erythrocyte senescence2013
- Author(s)
  Arashiki Nobuto, Kimata Naoki, Manno Sumie, Mohandas Narla, Takakuwa Yuichi
- Journal Title
  
  Biochemistry
  
  Volume: 52 Issue: 34 Pages: 5760-5769
- DOI
  10.1021/bi400405p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659485, KAKENHI-PROJECT-25460375
[Presentation] 神経ガイダンス因子セマフォリン3Aによるホスファチジルセリン表在化のシグナル経路解析2023
- Author(s)
  新敷　信人、土井　蒔子、中村　史雄
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06211
[Presentation] 神経ガイダンス因子セマフォリン3Aによる細胞膜リン脂質非対称性崩壊の解析2022
- Author(s)
  新敷　信人、中村　史雄
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06211
[Presentation] New insight into the regulatory mechanism of membrane lipid scrambling in human erythrocyte: Inhibitory effect of cholesterol on PLSCR1-mediated phospholipid scrambling2015
- Author(s)
  Nobuto Arashiki, Yuichi Takakuwa
- Organizer
  Gordon Research Conference, Red Cells
- Place of Presentation
  Holderness, NH, USA
- Year and Date
  2015-06-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] Maintenance, regulation and disorder of asymmetric distribution of phospholipids in the bilayer of human erythrocyte membranes2015
- Author(s)
  Yuichi Takakuwa, Nobuto Arashiki, Ichiro Koshino
- Organizer
  Gordon Research Conference
- Place of Presentation
  ニューハンプシャー（アメリカ）
- Year and Date
  2015-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-26461515
[Presentation] ATP11C Encodes a Major Flippase in Human Erythrocyte and Its Genetic Defect Causes Congenital Non-Spherocytic Hemolytic Anemia2015
- Author(s)
  Arashiki Nobuto, Takakuwa Yuichi, Kanno Hitoshi
- Organizer
  57th Annual Meeting and Exposition of American Society of Hematology
- Place of Presentation
  Orland, FL, USA
- Year and Date
  2015-12-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] 赤血球膜におけるリン脂質スクランブラーゼPLSCR1の多量体形成2015
- Author(s)
  新敷信人, 高桑雄一
- Organizer
  日本膜学会第37年会
- Place of Presentation
  早稲田大学（東京都新宿区）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] ヒト赤血球膜におけるリン脂質スクランブリングのコレステロールによる抑制機構2015
- Author(s)
  新敷信人, 高桑雄一
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  一橋大学一橋講堂（東京都千代田区）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] Maintenance, Regulation, and Disorder of Asymmetric Distribution of Phospholipids in the Bilayer of Human Erythrocyte Membrane2015
- Author(s)
  Yuichi Takakuwa, Nobuto Arashiki, Ichiro Koshino
- Organizer
  Gordon Research Conference, Red cells
- Place of Presentation
  Holderness, NH, USA
- Year and Date
  2015-07-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] ヒト赤血球膜におけるスクランブラーゼPLSCR1のリン脂質輸送メカニズム2015
- Author(s)
  新敷信人, 高桑雄一
- Organizer
  第38回日本分子生物学会年会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] コレステロール移動亢進が溶血の原因となる可能性の検討2014
- Author(s)
  新敷信人、高桑雄一
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス（大阪府・東大阪市）
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] 赤血球膜-リポタンパク質間コレステロール移動におけるハプトグロビンの役割2014
- Author(s)
  新敷信人、高桑雄一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会議場（京都府・京都市）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] 赤血球膜-リポタンパク質間におけるコレステロール移動の解析2014
- Author(s)
  新敷信人、高桑雄一
- Organizer
  日本膜学会第36年会
- Place of Presentation
  早稲田大学（東京都・新宿区）
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] 脂質過酸化によってバンド3タンパク質に生じるメトヘモグロビンとの結合様式の変化のメカニズム2013
- Author(s)
  新敷信人、萬野純恵、高桑雄一
- Organizer
  日本膜学会第35年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] 赤血球‐リポタンパク質間のコレステロール移動のメカニズム2013
- Author(s)
  新敷信人、高桑雄一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460375

1. KOSHINO Ichiro (80328377)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. TAKAKUWA Yuichi (40113740)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. TANAKA Shotaro (90380667)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MANNO Sumie (10101205)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. SAITO Masaki (50400271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 中村史雄 (10262023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 實木葵 (80760074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Mohandas Narla

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

arashiki nobuto 新敷 信人

新敷 信人 アラシキ ノブト

ARASHIKI Nobuto 新敷 信人

Research Projects

Research Products

Co-Researchers

An identification of the signaling pathway involving in Sema3A-induced breakdown of the asymmetric distribution in the developing neuron's membranePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of purine nucleotide receptor signaling in P. falciparum invasion of erythrocytes.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on PKA phosphorylation events in host red cells during invasion by Plasmodium falciparum

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An inhibitory effect of cholesterol on expressing eat me signals in human erythrocyte membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of a novel role for lidocaine as a wide range spectrum anti-infection drug

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ヒト赤血球の寿命を規定するメカニズム2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Membrane peroxidation and methemoglobin formation are both necessary for band 3 clustering: mechanistic insights into human erythrocyte senescence2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 神経ガイダンス因子セマフォリン3Aによるホスファチジルセリン表在化のシグナル経路解析2023

Author(s)

Organizer

Data Source

[Presentation] 神経ガイダンス因子セマフォリン3Aによる細胞膜リン脂質非対称性崩壊の解析2022

Author(s)

Organizer

Data Source

[Presentation] New insight into the regulatory mechanism of membrane lipid scrambling in human erythrocyte: Inhibitory effect of cholesterol on PLSCR1-mediated phospholipid scrambling2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Maintenance, regulation and disorder of asymmetric distribution of phospholipids in the bilayer of human erythrocyte membranes2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ATP11C Encodes a Major Flippase in Human Erythrocyte and Its Genetic Defect Causes Congenital Non-Spherocytic Hemolytic Anemia2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 赤血球膜におけるリン脂質スクランブラーゼPLSCR1の多量体形成2015

Author(s)

Organizer

arashiki nobuto 新敷信人

新敷信人アラシキノブト

ARASHIKI Nobuto 新敷信人