Mizuma Masamichi 水間正道

… Alternative Names

MIZUMA Masamichi 水間正道

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Researcher Number	80578675
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 東北大学, 大学病院, 講師 2020 – 2023: 東北大学, 大学病院, 講師 2015 – 2019: 東北大学, 大学病院, 助教 2011 – 2013: 東北大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 膵神経内分泌腫瘍 / CNPY2 / 神経内分泌腫瘍 / collagen XVII / 膵癌 / COL17A1 / collagen XⅦ / 膵・消化管神経内分泌腫瘍 / 転移 / 膵臓 … More / 肝転移 / 胆管癌 / 癌幹細胞様細胞 / Notch … More Except Principal Investigator 膵癌 / 予後因子 / メタボロミクス / 術前診断 / バイオマーカー / 胆嚢癌 Less

癌関連線維芽細胞のSMAD3-PTGDR2 axis活性化による膵癌新規治療の開発Principal Investigator
- Principal Investigator
  
  水間正道
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
人工知能を用いた医用画像と膵液バイオマーカーの統合解析による小膵癌診断技法の構築
- Principal Investigator
  
  畠達夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
膵癌術前治療耐性克服を目指したcollagen XVIIを標的とする新規治療開発Principal Investigator
- Principal Investigator
  
  水間正道
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
Elucidation of liver metastasis-related mechanisms in CNPY2 for gastroenteropancreatic neuroendocrine tumorPrincipal Investigator
- Principal Investigator
  
  Mizuma Masamichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
Prognostic factor analysis of gallbladder cancer by blood metabolomics
- Principal Investigator
  
  Nakagawa Kei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku University
Elucidation of molecular mechanism in liver metastasis of gastroenteropancreatic neuroendocrine tumorsPrincipal Investigator
- Principal Investigator
  
  Mizuma Masamichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
Establishment of novel targeted therapy by inhibition of Notch signaling pathway in biliary tract cancerPrincipal Investigator
- Principal Investigator
  
  MIZUMA Masamichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University

All 2023 2022 2018 2013 2012 2011

All Journal Article Presentation

[Journal Article] Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment2023
- Author(s)
  Kashiwagi Ryosuke、Funayama Ryo、Aoki Shuichi、Matsui Aya、Klein Sebastian、Sato Yukihiro、Suzuki Tsubasa、Murakami Keigo、Inoue Koetsu、Iseki Masahiro、Masuda Kunihiro、Mizuma Masamichi、Naito Hisamichi、Duda Dan G.、Unno Michiaki、Nakayama Keiko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 11 Pages: 4286-4298
- DOI
  10.1111/cas.15952
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08816, KAKENHI-PROJECT-21K08725, KAKENHI-PROJECT-22K19520, KAKENHI-PLANNED-22H05063, KAKENHI-PROJECT-20H03435, KAKENHI-PROJECT-21H02458, KAKENHI-PROJECT-21H02996
[Journal Article] Simultaneous and sequential combination of genetic and epigenetic biomarkers for the presence of high-grade dysplasia in patients with pancreatic cyst: Discovery in cyst fluid and test in pancreatic juice2023
- Author(s)
  Hata T, Mizuma M, Kusakabe T, Amano H, Furukawa T, Iwao T, Unno M.
- Journal Title
  
  Pancreatology
  
  Volume: 23 Issue: 2 Pages: 218-226
- DOI
  10.1016/j.pan.2023.01.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08765
[Journal Article] A novel liver metastasis-correlated protein of pancreatic neuroendocrine neoplasm (PanNEN) discovered by proteomic analysis2018
- Author(s)
  Shimura M, Mizuma M, et al.
- Journal Title
  
  Oncotarget
  
  Volume: 掲載確定
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10179
[Journal Article] Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system2012
- Author(s)
  Shima K, et al
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 31 Issue: 1 Pages: 55-61
- DOI
  10.1186/1756-9966-31-55
- URL
  http://www.jeccr.com/content/31/1/55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390253, KAKENHI-PROJECT-23590452, KAKENHI-PROJECT-23791514, KAKENHI-PROJECT-23791515, KAKENHI-PROJECT-24390118, KAKENHI-PROJECT-24659487
[Presentation] Collagen XVIIはCXCL10/CXCR3の免疫応答経路を介して膵癌腫瘍形成を抑制する2023
- Author(s)
  柏木良介, 舟山亮, 青木修一, 平野直大, 安藤未佳, 井上亨悦, 伊関雅裕, 三浦孝之, 石田晶玄, 大塚英郎, 水間正道, 中川圭, 森川孝則, 亀井尚, 海野倫明, 中山啓子
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22K08816
[Presentation] 膵病変の診断・リスク評価における連続膵液細胞診と膵液中のKRAS/GNAS遺伝子測定の有用性2022
- Author(s)
  畠達夫, 水間正道, 天野穂高, 日下部崇, 岩尾年康, 海野倫明
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22K08765
[Presentation] Impact of genome/epigenome biomarker testing using serially harvested pancreatic juice samples in patients with IPMN2022
- Author(s)
  Tatsuo Hata, Masamichi Mizuma, Hodaka Amano, Takashi Kusakabe, Toshiyasu Iwao, Michiaki Unno
- Organizer
  Joint Congress of the 26th Meeting of International Association of Pancreatology (IAP) and the 53th Annual Meeting of Japan Pancreas Society (JPS)（シンポジウム）
- Data Source
  KAKENHI-PROJECT-22K08765
[Presentation] Usefulness of genome/epigenome markers in pancreatic juice to detect high-grade dysplastic lesions.2022
- Author(s)
  Tatsuo Hata, Masamichi Mizuma, Hodaka Amano, Toshiyasu Iwao, Michiaki Unno
- Organizer
  第77回消化器外科学会総会（シンポジウム）
- Data Source
  KAKENHI-PROJECT-22K08765
[Presentation] プロテオミクス解析により発見した膵神経内分泌腫瘍の新規肝転移関連因子2018
- Author(s)
  志村充広、水間正道、ほか
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-15K10179
[Presentation] 蛍光NOGマウスの異種移植モデルを用いた高純度癌細胞サンプリングシステム2013
- Author(s)
  嶋健太郎、水間正道、ほか
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2013-04-13
- Data Source
  KAKENHI-PROJECT-23791514
[Presentation] Utility of xenograft models using NOG-eGFP mice for a high quality sampling system of Pancreato-Biliary cancer cells2012
- Author(s)
  Shima K, Mizuma M, et al
- Organizer
  International Hepato-Pancreato Biliary Association 2012
- Place of Presentation
  Paris , France
- Year and Date
  2012-07-03
- Data Source
  KAKENHI-PROJECT-23791514
[Presentation] An attempt to establish a high quality sampling system of cancer cells using a xenograft model of NOG-EGFP mice2011
- Author(s)
  嶋健太郎、水間正道、ほか
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23791514

1. 高舘達之 (50772216)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 畠達夫 (30806237)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. 青木修一 (30844451)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. TACHIKAWA Masanori (00401810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Nakagawa Kei (20542294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 川口桂 (10700164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中山啓子 (60294972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 舟山亮 (20452295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. ISEKI Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHIMURA Mitsuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. KATOH Yasutake

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Mizuma Masamichi 水間 正道

MIZUMA Masamichi 水間 正道

Research Projects

Research Products

Co-Researchers

癌関連線維芽細胞のSMAD3-PTGDR2 axis活性化による膵癌新規治療の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

人工知能を用いた医用画像と膵液バイオマーカーの統合解析による小膵癌診断技法の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

膵癌術前治療耐性克服を目指したcollagen XVIIを標的とする新規治療開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of liver metastasis-related mechanisms in CNPY2 for gastroenteropancreatic neuroendocrine tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prognostic factor analysis of gallbladder cancer by blood metabolomics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanism in liver metastasis of gastroenteropancreatic neuroendocrine tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of novel targeted therapy by inhibition of Notch signaling pathway in biliary tract cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous and sequential combination of genetic and epigenetic biomarkers for the presence of high-grade dysplasia in patients with pancreatic cyst: Discovery in cyst fluid and test in pancreatic juice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel liver metastasis-correlated protein of pancreatic neuroendocrine neoplasm (PanNEN) discovered by proteomic analysis2018

Author(s)

Journal Title

Data Source

[Journal Article] Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system2012

Author(s)

Journal Title

DOI

URL

Data Source

[Presentation] Collagen XVIIはCXCL10/CXCR3の免疫応答経路を介して膵癌腫瘍形成を抑制する2023

Author(s)

Organizer

Data Source

[Presentation] 膵病変の診断・リスク評価における連続膵液細胞診と膵液中のKRAS/GNAS遺伝子測定の有用性2022

Author(s)

Organizer

Data Source

[Presentation] Impact of genome/epigenome biomarker testing using serially harvested pancreatic juice samples in patients with IPMN2022

Author(s)

Organizer

Data Source

[Presentation] Usefulness of genome/epigenome markers in pancreatic juice to detect high-grade dysplastic lesions.2022

Mizuma Masamichi 水間正道

MIZUMA Masamichi 水間正道