Machida Takeshi 町田豪

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MACHIDA TAKESHI 町田豪

MACHIDA Takeshi 町田豪

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Researcher Number	80583632
Other IDs
Affiliation (Current)	2022: 福島県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2018 – 2022: 福島県立医科大学, 医学部, 講師 2014 – 2015: 福島県立医科大学, 医学部, 助教 2012: 福島県立医科大学, 医学部・免疫学講座, 助教 2011 – 2012: 福島県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Immunology / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 49070:Immunology-related Except Principal Investigator Basic Section 49070:Immunology-related / Collagenous pathology/Allergology
Keywords	Principal Investigator 全身性エリテマトーデス / ループス腎炎 / MRL/lprマウス / 補体第二経路 / アレルギー・免疫関連疾患 / MASP-1 / MRL/lpr / Marginal zone-B細胞 / 抗dsDNA抗体 / 糸球体腎炎 … More / IFN-γ受容体 / TLR7 / SLEモデル / Marginal zone B細胞 / 自己抗体産生 / MASP-3 / 共免疫沈降 / ノックアウトマウス / 補体 … More Except Principal Investigator 補体 / レクチン経路 / 第二経路 / MASP-1/3 / MAp44 / 補体因子 / MASP-3 / 認識分子 / 補体レクチン経路 / レクチン経路の糖鎖認識分子 / 補体活性化 / セリンプロテアーゼ / 補体制御因子 Less

Serpinによる補体第二経路D因子の新規な制御機構
- Principal Investigator
  
  関根英治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Fukushima Medical University
Identification of the protease in blood that activates complement factor MASP-3Principal Investigator
- Principal Investigator
  
  町田豪
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Fukushima Medical University
Elucidation of the activation mechanism of the complement factor MASP-3 of the alternative complement pathway
- Principal Investigator
  
  Sekine Hideharu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Fukushima Medical University
The role for splenic marginal zone-B cells in autoantibody production in systemic lupus erythematosusPrincipal Investigator
- Principal Investigator
  
  Machida Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Fukushima Medical University
Development of complement component MASP-1/3 inhibitors for treatment of lupus animal models.
- Principal Investigator
  
  SEKINE Hideharu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Fukushima Medical University
Function analysis of MASP-1 as a therapeutic target for lupus-pronenephritis in MRL/lpr micePrincipal Investigator
- Principal Investigator
  
  MACHIDA Takeshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Fukushima Medical University

All 2022 2021 2020 2019 2018 2015 2014 2012 2011 Other

All Journal Article Presentation

[Journal Article] ARMS2 and CFH polymorphism and intraocular complement activation in neovascular age-related macular degeneration2022
- Author(s)
  Yutaka Kato, Yasuharu Oguchi, Tomoko Omori, Akihito Kasai, Masashi Ogasawara, Yukinori Sugano, Kanako Itagaki, Akira Ojima, Yumi Ishida, Takeshi Machida, Hideharu Sekine, Tetsuju Sekiryu
- Journal Title
  
  Ophthalmology Science
  
  Volume: In press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07083
[Journal Article] Changes in complement activation products after anti‐VEGF injection for choroidal neovascularization in age‐related macular degeneration and pachychoroid disease2021
- Author(s)
  Tanaka Keiichiro、Oguchi Yasuharu、Omori Tomoko、Ishida Yumi、Shintake Hiroaki、Tomita Ryutaro、Kasai Akihito、Ogasawara Masashi、Sugano Yukinori、Itagaki Kanako、Ojima Akira、Machida Takeshi、Sekine Hideharu、Sekiryu Tetsuju
- Journal Title
  
  Sci Rep
  
  Volume: 11 Pages: 8464-8464
- DOI
  10.1038/s41598-021-87340-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18882, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-20K09776, KAKENHI-PROJECT-21K07083
[Journal Article] Anaphylatoxin concentration in aqueous and vitreous humor in the eyes with vitreoretinal interface abnormalities2020
- Author(s)
  Yasuharu Oguchi , Tetsuju Sekiryu , Tomoko Omori , Yutaka Kato , Masashi Ogasawara , Yukinori Sugano , Kanako Itagaki , Akira Ojima , Takeshi Machida , Hideharu Sekine
- Journal Title
  
  Experimental Eye Research
  
  Volume: 195 Pages: 108025-108025
- DOI
  10.1016/j.exer.2020.108025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11427, KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K08392
[Journal Article] Complement Activation Products and Cytokines in Pachychoroid Neovasculopathy and Neovascular Age-Related Macular Degeneration2020
- Author(s)
  Kato Yutaka、Oguchi Yasuharu、Omori Tomoko、Shintake Hiroaki、Tomita Ryutaro、Kasai Akihito、Ogasawara Masashi、Sugano Yukinori、Itagaki Kanako、Ojima Akira、Machida Takeshi、Sekine Hideharu、Sekiryu Tetsuju
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 61 Pages: 39-39
- DOI
  10.1167/iovs.61.13.39
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-20K09776, KAKENHI-PROJECT-19K18882
[Journal Article] Evidence for activation of lectin and classical pathway complement components in aqueous humor of neovascular age-related macular degeneration2020
- Author(s)
  Omori T, Oguchi Y, Machida T, Kato Y, Ishida Y, Ojima A, Itagaki K, Shintake H, Tomita R, Kasai A, Sugano
- Journal Title
  
  Ophthalmic Research
  
  Volume: 63 Pages: 252-258
- DOI
  10.1159/000503258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11427, KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-18K08392
[Journal Article] A novel complement inhibitor sMAP‐FH targeting both the lectin and alternative complement pathways2020
- Author(s)
  Takasumi M, Omori T, Machida T, Ishida Y, Hayashi M, Suzuki T, Homma Y, Endo Y, Takahashi M, Ohira H, Fujita T, Sekine H
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Pages: 6598-6612
- DOI
  10.1096/fj.201902475r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K08392
[Journal Article] Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway2019
- Author(s)
  Manabu Hayashi, Takeshi Machida, Yumi Ishida, Yusuke Ogata, Tomoko Omori, Mika Takasumi, Yuichi Endo, Toshiyuki Suzuki, Masayuki Sekimata, Yoshimi Homma, Masahito Ikawa, Hiromasa Ohira, Teizo Fujita, and Hideharu Sekine
- Journal Title
  
  the J Immunol
  
  Volume: 203 Pages: 1411-1416
- DOI
  10.4049/jimmunol.1900605
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-18K08895, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K15789, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17K16975
[Journal Article] Complement Activation by Autoantigen Recognition in the Growth Process of Benign Prostatic Hyperplasia2019
- Author(s)
  Hata Junya、Machida Takeshi、Matsuoka Kanako、Hoshi Seiji、Akaihata Hidenori、Hiraki Hiroyuki、Suzuki Toshiyuki、Ogawa Soichiro、Kataoka Masao、Haga Nobuhiro、Ishibashi Kei、Homma Yoshimi、Sekine Hideharu、Kojima Yoshiyuki
- Journal Title
  
  SOCIENTIFIC REPORTS
  
  Volume: 9 Pages: 00-00
- DOI
  10.1038/s41598-019-57001-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-19K09733, KAKENHI-PROJECT-17K16802
[Journal Article] Response to Comment on “Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway”2019
- Author(s)
  Takeshi Machida, Manabu Hayashi, Teizo Fujita, and Hideharu Sekine
- Journal Title
  
  The Journal of Immunology
  
  Volume: 203 Pages: 3091-3092
- DOI
  10.4049/jimmunol.1901087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-19K07610
[Journal Article] Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice2018
- Author(s)
  Takeshi Machida, Natsumi Sakamoto, Yumi Ishida, Minoru Takahashi, Teizo Fujita, and Hideharu Sekine
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 1191-1191
- DOI
  10.3389/fimmu.2018.01191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08392
[Journal Article] 補体異常値を示す疾患とそのメカニズム2015
- Author(s)
  関根英治、大森智子、町田　豪
- Journal Title
  
  補体
  
  Volume: 52 Pages: 14-26
- NAID
  40020953030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670478
[Journal Article] Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces.2014
- Author(s)
  Takeshi Machida, Natsumi Sakamoto, Tomoko Omori, and Hideharu Sekine
- Journal Title
  
  Proceedings of the Japanese Society for Immunology
  
  Volume: 43 Pages: 189-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670478
[Journal Article] A dual role for IFN-γ in development of peripheral B cells in lupus-prone MRL/lpr mice.2014
- Author(s)
  Takeshi Machida, Natsumi Sakamoto, Gary S. Gilkeson, and Hideharu Sekine
- Journal Title
  
  Arthritis Rheum
  
  Volume: 66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670478
[Journal Article] Involvement of both the lectin and classical pathways in peanut-induced complement activation and anaphylaxis2012
- Author(s)
  Kodama T,Sekine H,Endo Y,Takahashi M,Iwaki D,Machida T,Kanno K,Ishida Y,Fujita T
- Journal Title
  
  Immunobiology
  
  Volume: 218 Pages: 844-844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790542
[Journal Article] Chloroplastic NADPH-dependent thioredoxin reductase in Chlorella vulgaris alleviates environmental stresses in yeast with 2-Cys peroxiredoxin2012
- Author(s)
  Machida T,Ishibashi A,Kirino A,Sato J,Kawasaki S,Niimura Y,Honjoh K,Miyamoto T
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790542
[Journal Article] Chloroplastic NADPH- dependent thioredoxin reductase in Chlorella vulgaris alleviates environmental stresses in yeast with 2-Cys peroxiredoxin2012
- Author(s)
  Takeshi Machida
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- DOI
  10.1371/journal.pone.0045988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790542
[Journal Article] Circulating myeloid-derived suppressor cells are increased and correlate to immune supperssion,inflammation,and hypoproteinemia in patients with cancer2012
- Author(s)
  Ohki S,Shibata M,Gonda K,Machida T,Shimura T,Nakamura I.Ohtake T,Koyama Y.Suzuki S.Ohto H.Takenoshita S
- Journal Title
  
  Oncol Rep
  
  Volume: 28 Pages: 453-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] MASP-3の活性化におけるレクチン経路の認識分子の役割2021
- Author(s)
  草刈　浩平、石田　由美、大森　智子、鈴木　俊幸、関亦　正幸、町田　豪、関根　英治
- Organizer
  日本補体学会
- Data Source
  KAKENHI-PROJECT-19K07610
[Presentation] The significance of complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway in the long-term retention of MASP-3 in the circulation2021
- Author(s)
  Takeshi Machida, Kohei Kusakari, Yumi Ishida, Tomoko Omori, Toshiyuki Suzuki, Masayuki Sekimata, Teizo Fujita, and Hideharu Sekine
- Organizer
  28th International Complement Virtual Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07610
[Presentation] The significance of complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway in the long-term retention of MASP-3 in the circulation2021
- Author(s)
  Takeshi Machida, Kohei Kusakari, Yumi Ishida, Tomoko Omori, Toshiyuki Suzuki, Masayuki Sekimata, Teizo Fujita, and Hideharu Sekine
- Organizer
  28th International Complement Virtual Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07083
[Presentation] MASP-3 の活性化におけるレクチン経路の認識分子の役割2021
- Author(s)
  草刈浩平、石田由美、大森智子、鈴木俊幸、関亦正幸、町田豪、関根英治
- Organizer
  第57回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07083
[Presentation] A FUSION PROTEIN OF SMAP AND FACTOR H INHIBITS BOTH THE LECTIN AND ALTERNATIVE COMPLEMENT PATHWAYS IN VIVO2019
- Author(s)
  Hideharu Sekine, Mika Takasumi, Tomoko Omori, Takeshi Machida, Yumi Ishida, and Teizo Fujita
- Organizer
  The 17th European Meeting on Complement in Human Disease (EMCHD 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07610
[Presentation] SLEモデルMRL/lprマウスの抗dsDNA抗体産生における脾臓辺縁帯B細胞の役割2018
- Author(s)
  町田豪、関根英治
- Organizer
  Rheumatology Conference 2018
- Data Source
  KAKENHI-PROJECT-18K08392
[Presentation] マウス型リコンビナントタンパクrmMAp44-PA, rmMAp44-Igの作製と補体レクチン経路の阻害作用2015
- Author(s)
  高住美佳、高橋実、大森智子、町田豪、坂本夏美、石田由美、関根英治
- Organizer
  日本補体学会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26670478
[Presentation] 補体因子MASP-1/3欠損のMRL/lprマウスでは補体第二経路の活性化が抑制され、糸球体腎炎が改善される2015
- Author(s)
  坂本夏美、町田豪、高橋実、関根英治
- Organizer
  Rheumatology Conference 2015
- Place of Presentation
  東京都中央区
- Year and Date
  2015-06-06
- Data Source
  KAKENHI-PROJECT-26670478
[Presentation] Lack of interferon regulatory factor-1 accelerates development of interstitial nephritis, renal vasculitis, and pulmonary granulomas with predominant Th2 polarity in MRL/lpr mice2012
- Author(s)
  Takeshi Machida
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場, 兵庫
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] Role of complement in a murine model of peanut-induced anaphylaxis2012
- Author(s)
  Kodama T, Endo Y, Takahashi M, IwakiD, Machida T, Fujita T, Sekine H
- Organizer
  XXIV International Complement Workshop
- Place of Presentation
  Crete, Greece
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] MRL/lprマウスで系統特異的に観察されるIFN-γ誘導性B細胞欠損2012
- Author(s)
  町田豪、坂本夏美、山内直人、関根英治
- Organizer
  研究連携セミナー2012
- Place of Presentation
  福島県立医科大学
- Year and Date
  2012-12-18
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] IRF-1 deficient lupus-prone MRL/lpr mice show reduced glomerulonephritis but develop severe interstitial nephritis, renal vasculitis and pulmonary granulomas with propensity for Th2 polarity2012
- Author(s)
  Sekine H, Machida T, Sakamoto N, SuzukiE, Zhang X, Reily CM, Gilkeson GS
- Organizer
  IRF-1 deficient lupus-prone MRL/lpr mice show reduced glomerulonephritis but develop severe interstitial nephritis, renal vasculitis and pulmonary granulomas with propensity for Th2 polarity
- Place of Presentation
  Washington DC, USA
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] Lack of interferon regulatory factor-1 accelerates development of interstitial nephritis, renal vasculitis, and pulmonary granulomas with predominant Th2 polarity in MRL/lpr mice2012
- Author(s)
  Machida T, Sakamoto N, Suzuki E, Zhang X, Reily CM, Gilkeson GS, Sekine H
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] MRL/lprマウスで系統特異的に観察されるIFN-γ誘導性B細胞欠損2012
- Author(s)
  町田　豪
- Organizer
  研究連携セミナーポスター発表会2012
- Place of Presentation
  福島県立医科大学, 福島
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] IRF-4 deficient lupus-prone MRL/lpr mice develop granulomatous lesions in multiple organs with strong propensity for Th1 polarity.2011
- Author(s)
  町田豪
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] Interferon regulatory factor-4 deficient lupus-prone MRL/lpr mice show strong propensity for Th1 polarity and develop granulomatous lesions in multiple organs2011
- Author(s)
  Sekine H, Machida T, Suzuki E, KinserTTH, Avila EM, Ruiz P, Reilly CM, Gilkeson GS
- Organizer
  2011-Annual Scientific Meeting of the American College of Rheumatology
- Place of Presentation
  Chicago, USA
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] IRF-4 deficient lupus-prone MRL/lprmice develop granulomatous lesions in multiple organs with strong propensity for Th1 polarity2011
- Author(s)
  Machida T, Honma K, Matsuyama T, YuiK, Ruiz P, Fujita T, Gilkeson GS, Sekine H
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23790542
[Presentation] Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces.
- Author(s)
  Takeshi Machida, Natsumi Sakamoto, Tomoko Omori, and Hideharu Sekine
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26670478
[Presentation] Takeshi Machida, Natsumi Sakamoto, Gary S. Gilkeson, and Hideharu Sekine, A dual role for IFN-γ in development of peripheral B cells in lupus-prone MRL/lpr mice.
- Author(s)
  Takeshi Machida, Natsumi Sakamoto, Gary S. Gilkeson, and Hideharu Sekine
- Organizer
  2014-Annual Scientific Meeting of the American College of Rheumatology
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2014-11-13 – 2014-11-18
- Data Source
  KAKENHI-PROJECT-26670478

1. SEKINE Hideharu (40363759)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
2. TAKAHASHI MINORU (00285024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 林学 (80745787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. SEKIRYU Tetsuju

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. OJIMA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. ISHIBASHI Kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. HATA Junya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 村上明子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 関亦正幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 大森智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
12. 小島祥敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 羽賀宣博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 赤井畑秀則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 笠井暁仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Machida Takeshi 町田 豪

MACHIDA TAKESHI 町田 豪

MACHIDA Takeshi 町田 豪

Research Projects

Research Products

Co-Researchers

Serpinによる補体第二経路D因子の新規な制御機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the protease in blood that activates complement factor MASP-3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the activation mechanism of the complement factor MASP-3 of the alternative complement pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role for splenic marginal zone-B cells in autoantibody production in systemic lupus erythematosusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of complement component MASP-1/3 inhibitors for treatment of lupus animal models.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function analysis of MASP-1 as a therapeutic target for lupus-pronenephritis in MRL/lpr micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ARMS2 and CFH polymorphism and intraocular complement activation in neovascular age-related macular degeneration2022

Author(s)

Journal Title

Data Source

[Journal Article] Changes in complement activation products after anti‐VEGF injection for choroidal neovascularization in age‐related macular degeneration and pachychoroid disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anaphylatoxin concentration in aqueous and vitreous humor in the eyes with vitreoretinal interface abnormalities2020

Author(s)

Journal Title

DOI

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[Journal Article] Complement Activation Products and Cytokines in Pachychoroid Neovasculopathy and Neovascular Age-Related Macular Degeneration2020

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[Journal Article] Evidence for activation of lectin and classical pathway complement components in aqueous humor of neovascular age-related macular degeneration2020

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[Journal Article] A novel complement inhibitor sMAP‐FH targeting both the lectin and alternative complement pathways2020

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[Journal Article] Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway2019

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[Journal Article] Complement Activation by Autoantigen Recognition in the Growth Process of Benign Prostatic Hyperplasia2019

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Machida Takeshi 町田豪

MACHIDA TAKESHI 町田豪

MACHIDA Takeshi 町田豪