Yokomizo Tomomasa 横溝智雅

Researcher Number	80590314
Other IDs
Affiliation (Current)	2025: 東京女子医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 東京女子医科大学, 医学部, 講師 2015 – 2021: 熊本大学, 国際先端医学研究機構, 特定事業研究員 2015: 熊本大学, 国際先端医学研究機構, 助教 2014: 順天堂大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields Except Principal Investigator Basic Section 50010:Tumor biology-related / Tumor therapeutics
Keywords	Principal Investigator 造血幹細胞 / 発生 / 移植・再生医療 / 発生・分化 / 造血システム / 造血発生 / 多能性幹細胞 / 血液 Except Principal Investigator 白血病 / 分子標的治療 … More / 分指標的治療 / マウスモデ / RUNX / マウスモデル / AYA世代がん / 内科 / トランスレーショナルリサーチ / 癌 Less

The physiological and evolutionary significance of the limited site and timing of hematopoietic stem cell developmentPrincipal Investigator
- Principal Investigator
  
  横溝智雅
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokyo Women's Medical University
Development of methods for inducing hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  横溝智雅
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Tokyo Women's Medical University
Elucidation of the molecular basis for age-dependent leukemogenesis towards a novel therapeutic strategy
- Principal Investigator
  
  大里元美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kumamoto University
Analysis of hematopoietic system development using lineage tracingPrincipal Investigator
- Principal Investigator
  
  Yokomizo Tomomasa
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokyo Women's Medical University
  Kumamoto University
Elucidating the mechanism of hematopoietic stem cell development and maturation by using a novel reporter mousePrincipal Investigator
- Principal Investigator
  
  Yokomizo Tomomasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Development of a novel therapeutic method against acute megakaryoblastic leukemia by NOTCH agonists
- Principal Investigator
  
  Osato Motomi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kumamoto University
Elucidating the mechanism of genome-wide transcriptional repression in hematopoietic stem cell developmentPrincipal Investigator
- Principal Investigator
  
  Yokomizo Tomomasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
  Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Metabolic regulation in erythroid differentiation by systemic ketogenesis in fasted mice2024
- Author(s)
  Ma Wenjuan、Arima Yuichiro、Umemoto Terumasa、Yokomizo Tomomasa、Xu Yuqing、Miharada Kenichi、Tanaka Yosuke、Suda Toshio
- Journal Title
  
  Experimental Hematology
  
  Volume: 129 Pages: 104124-104124
- DOI
  10.1016/j.exphem.2023.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18305, KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-23K27628, KAKENHI-PROJECT-23K27632
[Journal Article] Development of the hematopoietic system: expanding the concept of hematopoietic stem cell-independent hematopoiesis2024
- Author(s)
  Yokomizo Tomomasa、Suda Toshio
- Journal Title
  
  Trends in Cell Biology
  
  Volume: 34 Issue: 2 Pages: 161-172
- DOI
  10.1016/j.tcb.2023.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18305, KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-23K27632
[Journal Article] Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells2023
- Author(s)
  Koh CP., Bahirvani AG., Wang CQ., Yokomizo T., Ng CEL., Du L., Tergaonkar V., Voon DC., Kitamura H., Hosoi H., Sonoki T., Michelle MMH., Tan LJ., Niibori-Nambu A., Zhang Y., Perkins AS., Hossain Z., Tenen DG., Ito Y., Venkatesh B., Osato M.
- Journal Title
  
  Gene
  
  Volume: 851 Pages: 147049-147049
- DOI
  10.1016/j.gene.2022.147049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-21K16248, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18KK0440, KAKENHI-PROJECT-23K24165
[Journal Article] Hematopoietic system formation during embryogenesis2023
- Author(s)
  横溝智雅
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 64 Issue: 9 Pages: 869-874
- DOI
  10.11406/rinketsu.64.869
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-23K18305, KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-23K27632
[Journal Article] Childhood hematopoietic stem cells constitute the permissive window for RUNX1-ETO leukemogenesis.2023
- Author(s)
  Abdallah MG, Teoh VSI, Dutta B, Yokomizo T, Osato M.
- Journal Title
  
  Int J Hematol
  
  Volume: - Issue: 6 Pages: 830-838
- DOI
  10.1007/s12185-023-03605-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-23K24165
[Journal Article] Independent origins of fetal liver haematopoietic stem and progenitor cells2022
- Author(s)
  Yokomizo Tomomasa、Ideue Takako、Morino-Koga Saori、Tham Cheng Yong、Sato Tomohiko、Takeda Naoki、Kubota Yoshiaki、Kurokawa Mineo、Komatsu Norio、Ogawa Minetaro、Araki Kimi、Osato Motomi、Suda Toshio
- Journal Title
  
  Nature
  
  Volume: 609 Issue: 7928 Pages: 779-784
- DOI
  10.1038/s41586-022-05203-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-23K24165
[Journal Article] Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells2022
- Author(s)
  Takihara Yuji、Higaki Takumi、Yokomizo Tomomasa、Umemoto Terumasa、Ariyoshi Kazunori、Hashimoto Michihiro、Sezaki Maiko、Takizawa Hitoshi、Inoue Toshihiro、Suda Toshio、Mizuno Hidenobu
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 776-776
- DOI
  10.1038/s42003-022-03733-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-22K19549, KAKENHI-ORGANIZER-22H05092, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20H03289, KAKENHI-PROJECT-20K09774, KAKENHI-PLANNED-18H05492
[Journal Article] Hepatic leukemia factor-expressing paraxial mesoderm cells contribute to the developing brain vasculature2022
- Author(s)
  Koui Yuta、Ideue Takako、Boylan Michael、Anderson Matthew J.、Osato Motomi、Suda Toshio、Yokomizo Tomomasa、Mukouyama Yoh-suke
- Journal Title
  
  Biology Open
  
  Volume: 11 Issue: 9
- DOI
  10.1242/bio.059510
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-23K24165
[Journal Article] RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner2021
- Author(s)
  Abdallah Mohamed Gaber、Niibori-Nambu Akiko、Morii Mariko、Yokomizo Takako、Yokomizo Tomomasa, at al.
- Journal Title
  
  Leukemia
  
  Volume: 35 Issue: 10 Pages: 2983-2988
- DOI
  10.1038/s41375-021-01268-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02952, KAKENHI-PROJECT-19J40166, KAKENHI-PROJECT-17K07199, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-21K19512, KAKENHI-PROJECT-18KK0440, KAKENHI-PROJECT-23K21285
[Journal Article] Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates2021
- Author(s)
  Hashimoto Michihiro、Umemoto Terumasa、Nakamura-Ishizu Ayako、Matsumura Takayoshi、Yokomizo Tomomasa、Sezaki Maiko、Takizawa Hitoshi、Suda Toshio
- Journal Title
  
  Blood Advances
  
  Volume: 5 Issue: 6 Pages: 1594-1604
- DOI
  10.1182/bloodadvances.2020002410
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-18J20690, KAKENHI-PROJECT-19J00952, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H05284
[Journal Article] Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs2021
- Author(s)
  Jeon Hyojung、Asano Keigo、Wakimoto Arata、Kulathunga Kaushalya、Tran Mai Thi Nhu、Nakamura Megumi、Yokomizo Tomomasa、Hamada Michito、Takahashi Satoru
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 4374-4374
- DOI
  10.1038/s41598-021-83652-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07499, KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-20K21513, KAKENHI-PROJECT-21K15003
[Journal Article] Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors.,2019
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Terumasa Umemoto, Junichi Matsuo, Ryota Harai, Yoshihiko Kihara, Eri Nakamura, Norihiro Tada, Tomohiko Sato, Tomoiku Takaku, Akihiko Shimono, Hitoshi Takizawa, Naomi Nakagata, Seiichi Mori, Mineo Kurokawa, Daniel Tenen, Motomi Osato, Toshio Suda, and Norio Komatsu.
- Journal Title
  
  J Exp Med
  
  Volume: 216 Issue: 7 Pages: 1599-1614
- DOI
  10.1084/jem.20181399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18K16127, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-17K09958
[Journal Article] Runx Family Genes in Tissue Stem Cell Dynamics.2017
- Author(s)
  Wang CQ, Mok MM, Yokomizo T, Tergaonkar V, Osato M.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 962 Pages: 117-138
- DOI
  10.1007/978-981-10-3233-2_9
- ISBN
  9789811032318, 9789811032332
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04312, KAKENHI-PROJECT-26461454, KAKENHI-PROJECT-16K14613
[Journal Article] Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors.2016
- Author(s)
  Kaimakis P, de Pater E, Eich C, Solaimani Kartalaei P, Kauts ML, Vink CS, van der Linden R, Jaegle M, Yokomizo T, Meijer D, Dzierzak E.
- Journal Title
  
  Blood
  
  Volume: 127 Issue: 11 Pages: 1426-1437
- DOI
  10.1182/blood-2015-10-673749
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461454, KAKENHI-PROJECT-15H04312
[Journal Article] RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity.2016
- Author(s)
  Chin DW, Sakurai M, Nah GS, Du L, Jacob B, Yokomizo T, Matsumura T, Suda T, Huang G, Fu XY, Ito Y, Nakajima H, Osato M.
- Journal Title
  
  Blood Cancer J.
  
  Volume: 6 Issue: 1 Pages: e379-e379
- DOI
  10.1038/bcj.2015.105
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461454, KAKENHI-PROJECT-15H04312
[Journal Article] Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence.2016
- Author(s)
  Iizuka K, Yokomizo T, Watanabe N, Tanaka Y, Osato M, Takaku T, Komatsu N.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0156427-e0156427
- DOI
  10.1371/journal.pone.0156427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04312, KAKENHI-PROJECT-26461454, KAKENHI-PROJECT-16K14613
[Journal Article] Hematopoietic stem cell enhancer: a powerful tool in stem cell biology.2015
- Author(s)
  Koh CP, Ng CE, Nah GS, Wang CQ, Tergaonkar V, Matsumura T, Yokomizo T, Suda T, Osato M.
- Journal Title
  
  Histol Histopathol
  
  Volume: 30 Pages: 661-72
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04312
[Journal Article] Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation.2015
- Author(s)
  Solaimani Kartalaei P, Yamada-Inagawa T, Vink CS, de Pater E, van der Linden R, Marks-Bluth J, van der Sloot A, van den Hout M, Yokomizo T, van Schaick-Solernó ML, Delwel R, Pimanda JE, van IJcken WF, Dzierzak E.
- Journal Title
  
  J Exp Med
  
  Volume: 212 Issue: 1 Pages: 93-106
- DOI
  10.1084/jem.20140767
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04312
[Presentation] 造血幹細胞は卵黄嚢で発生するのか2023
- Author(s)
  横溝智雅
- Organizer
  第27 回造血器腫瘍研究会(広島大学広仁会館）
- Data Source
  KAKENHI-PROJECT-23K24165
[Presentation] Independent origins of fetal liver hematopoietic stem and progenitor cells2022
- Author(s)
  Tomomasa Yokomizo
- Organizer
  The 8th International Forum on Stem Cells, Virtual, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758
[Presentation] Tracing the origin of hierarchical hematopoietic structure in the fetal liver2022
- Author(s)
  Tomomasa Yokomizo
- Organizer
  The 51th Annual Scientific Meeting, International Society for Experimental Hematology, Edinburgh, UK
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08758
[Presentation] Tracing the origin of hierarchical hematopoietic structure in fetal liver2021
- Author(s)
  Tomomasa Yokomizo, Takako Ideue, Mineo Kurokawa, Norio Komatsu, Kimi Araki, Motomi Osato, Toshio Suda
- Organizer
  第１８回　幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-20K08758
[Presentation] In vivo tracing of hematopoietic stem and progenitor cell formation in the mouse embryo2020
- Author(s)
  Tomomasa Yokomizo, Takako Ideue, Kimi Araki, Mineo Kurokawa, Norio Komatsu, Motomi Osato, Toshio Suda
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08758
[Presentation] Fate tracing of Hlf+ hematopoietic clusters in the developing mouse embryo2019
- Author(s)
  Tomomasa Yokomizo, Takako Ideue, Mineo Kurokawa, Motomi Osato, Toshio Suda
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09958
[Presentation] Hlf expression marks the developmental pathway for hematopoietic stem cells but not for erythroid-myeloid progenitors2018
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Terumasa Umemoto, Tomoiku Takaku, Mohamed Gaber, Seiichi Mori, Mineo Kurokawa, Daniel G Tenen, Toshio Suda, Motomi Osato, Norio Komatsu
- Organizer
  第16回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-17K09958
[Presentation] Evi-1/Hlf axis regulates HSC maturation in the mouse embryo2018
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Terumasa Umemoto, Tomoiku Takaku, Toshio Suda, Mineo Kurokawa, Norio Komatsu, Motomi Osato
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09958
[Presentation] Hlf expression marks the developmental pathway for hematopoietic stem cells but not for erythroid-myeloid progenitors2018
- Author(s)
  Tomomasa Yokomizo, Seiichi Mori, Mineo Kurokawa, Motomi Osato, Norio Komatsu
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09958
[Presentation] Development of HSC-dependent and independent lineages in the mouse embryo2017
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Tomoiku Takaku, Seiichi Mori, Motomi Osato and Norio Komatsu
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-17K09958
[Presentation] Hlf expression marks developmental pathway for hematopoietic stem cells, but not for erythroid-myeloid progenitors2017
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Terumasa Umemoto, Tomoiku Takaku, Seiichi Mori, Mineo Kurokawa, Toshio Suda, Motomi Osato and Norio Komatsu
- Organizer
  21st international Runx conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09958
[Presentation] Developmental origins of HSC-dependent and independent lineages in the mouse embryo2017
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Tomoiku Takaku, Seiichi Mori, Motomi Osato and Norio Komatsu
- Organizer
  第７９回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09958
[Presentation] Cellular heterogeneity of hematopoietic clusters in the mouse embryo2016
- Author(s)
  Tomomasa Yokomizo
- Organizer
  Hematopoietic stem cell researchers symposium at IMS
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2016-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-26461454
[Presentation] Whole-mount three-dimensional analysis of hematopoietic development in the mouse embryonic head2016
- Author(s)
  Yokomizo T, Iizuka K, Osato M, Takaku T, Komatsu N
- Organizer
  JSPS-NUS Joint Symposium
- Place of Presentation
  Singapore (Singapore)
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04312
[Presentation] Whole-mount three-dimensional analysis of hematopoietic development in the mouse embryonic head2016
- Author(s)
  Yokomizo T, Iizuka K, Watanabe N, Tanaka Osato M, Takaku T, Komatsu N
- Organizer
  JSPS-NUS Joint Symposium
- Place of Presentation
  Singapore (Singapore)
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461454
[Presentation] Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal and adult hematopoietic stem cells2015
- Author(s)
  Osato M, Koh CP, Yokomizo T
- Organizer
  13th Stem Cell Symposium
- Place of Presentation
  University of Tokyo (Tokyo, Japan)
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461454
[Presentation] Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal and adult hematopoietic stem cells2015
- Author(s)
  Osato M, Koh CP, Yokomizo T
- Organizer
  13th Stem Cell Research Symposium
- Place of Presentation
  University of Tokyo (Tokyo, Japan)
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04312

1. Osato Motomi (90314286)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. MORI Seiichi (10334814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 指田吾郎 (70349447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 岩崎正幸 (70790913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IIZUKA Kazuhide

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 多田昇弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 濱田理人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yokomizo Tomomasa 横溝 智雅

Research Projects

Research Products

Co-Researchers

The physiological and evolutionary significance of the limited site and timing of hematopoietic stem cell developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of methods for inducing hematopoietic stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular basis for age-dependent leukemogenesis towards a novel therapeutic strategy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of hematopoietic system development using lineage tracingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the mechanism of hematopoietic stem cell development and maturation by using a novel reporter mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel therapeutic method against acute megakaryoblastic leukemia by NOTCH agonists

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidating the mechanism of genome-wide transcriptional repression in hematopoietic stem cell developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Metabolic regulation in erythroid differentiation by systemic ketogenesis in fasted mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of the hematopoietic system: expanding the concept of hematopoietic stem cell-independent hematopoiesis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hematopoietic system formation during embryogenesis2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Childhood hematopoietic stem cells constitute the permissive window for RUNX1-ETO leukemogenesis.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Independent origins of fetal liver haematopoietic stem and progenitor cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells2022

Author(s)

Yokomizo Tomomasa 横溝智雅