KIKUCHI Shinsuke 菊地信介

Researcher Number	80596297
Other IDs
Affiliation (Current)	2025: 旭川医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 旭川医科大学, 医学部, 講師 2016 – 2020: 旭川医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55030:Cardiovascular surgery-related / Cardiovascular surgery Except Principal Investigator Basic Section 55030:Cardiovascular surgery-related
Keywords	Principal Investigator 末梢動脈疾患 / 静脈グラフト / 閉塞性動脈硬化症 / 大伏在静脈 / 静脈弁 / グラフト狭窄 / 下肢動脈疾患 / 内膜肥厚 / 足部重症度 / 包括的高度慢性下肢虚血 … More / 重症虚血肢 / 自家静脈 / 血行再建術 / バイパス術 / 弁 / 下肢動脈バイパス術 / グラフト不全 / 末梢バイパス術 / 重症虚血 / 外科的血行再建 / 弁部内膜肥厚 / 自家静脈グラフト / 下肢動脈バイパス / 弁部 … More Except Principal Investigator 内膜肥厚 / 閉塞性動脈硬化症 / 静脈グラフト / ROS / FIR / FIRAPY / 遠赤外線 / 冠動脈バイパス / 下肢末梢動脈バイパス / グラフト狭窄 / ヒートショックプロテイン / 熱ショック蛋白 / 活性酸素種 / VSMC / 線維芽細胞 / 血管平滑筋細胞 / 重症下肢虚血 / 自家静脈グラフト / 血行再建 / 血管内皮前駆細胞 / 末梢動脈疾患 / 酸化ストレス / 生活習慣病 / マイクロRNA / 幹細胞機能 / 生命予後 / 下肢閉塞性動脈硬化症 Less

静脈グラフト内膜肥厚における外膜細胞由来細胞外小胞の役割と外膜前駆細胞の重要性Principal Investigator
- Principal Investigator
  
  菊地信介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Asahikawa Medical College
包括的高度慢性下肢虚血が与える自家静脈グラフトへの分子細胞学的影響Principal Investigator
- Principal Investigator
  
  菊地信介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Asahikawa Medical College
遠赤外線照射による熱ショック蛋白を介した血管内膜肥厚抑制の機序解明
- Principal Investigator
  
  内田大貴
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Asahikawa Medical College
Establishment of an animal method for controlling vein graft intimal thickening based on genetic analysis of clinical specimens
- Principal Investigator
  
  東信良
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Asahikawa Medical College
Development of FIR therapy for suppressing vascular intimal hyperplasia
- Principal Investigator
  
  UCHIDA DAIKI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Asahikawa Medical College
Clinical study of stem cell function in patients with peripheral arterial disease: Role of stem cell senescence in poor prognosis of patients.
- Principal Investigator
  
  Nobuyoshi Azuma
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Asahikawa Medical College
Identification and elucidating of function of cells involved with intimal hyperplasia in a valve site of vein graftPrincipal Investigator
- Principal Investigator
  
  Kikuchi Shinsuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Asahikawa Medical College
Mechanism of intimal hyperplasia development at valve site of human vein graftPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Shinsuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Asahikawa Medical College

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Super-Elderly Case of Acute Lower Limb Ischemia Treated with Indigo Aspiration System in Japan2024
- Author(s)
  Kikuchi Shinsuke、Ohira Seima、Doita Tsutomu、Kamada Keisuke、Kuriyama Naoya、Tamaru Yuya、Tatsukawa Takamitsu、Yoshida Yuri、Uchida Daiki、Azuma Nobuyoshi
- Journal Title
  
  Ann Vasc Dis
  
  Volume: 17 Issue: 1 Pages: 63-68
- DOI
  10.3400/avd.cr.23-00095
- ISSN
  1881-641X, 1881-6428
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08910
[Journal Article] Venous Screening Activities at the Site of Hokkaido East Iburi Earthquake: Report from the Result of Venous Screening in Preventive Awareness Activities2023
- Author(s)
  Kamada Keisuke、Uchida Daiki、Okuda Hiroko、Koya Atsuhiro、Ohira Seima、Ikura Maiko、Kikuchi Shinsuke、Hanzawa Kazuhiko、Azuma Nobuyoshi
- Journal Title
  
  Ann Vasc Dis
  
  Volume: 16 Issue: 3 Pages: 163-168
- DOI
  10.3400/avd.oa.23-00046
- NAID
  130007977694
- ISSN
  1881-641X, 1881-6428
- Year and Date
  2023-09-25
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08910
[Journal Article] Giant Superior Mesenteric Artery Aneurysm Treated by Endovascular Treatment in a Very Elderly Female2023
- Author(s)
  Okubo Ryo、Kikuchi Shinsuke、Otani Norifumi、Tsutsui Masahiro、Kamiya Hiroyuki
- Journal Title
  
  Vascular Specialist International
  
  Volume: 39 Pages: 10-10
- DOI
  10.5758/vsi.230020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08910
[Journal Article] A case of lymphoma mimicking infected internal iliac artery aneurysm2023
- Author(s)
  Ichikawa Yohei、Kikuchi Shinsuke、Moriyama Hiroya、Tatsukawa Takamitsu、Ohira Seima、Kamikokura Yuki、Yoshida Yuri、Hatayama Mayumi、Yuzawa Sayaka、Wada Naoki、Uchida Daiki、Koya Atsuhiro、Azuma Nobuyoshi
- Journal Title
  
  Surgical Case Reports
  
  Volume: 9 Issue: 1 Pages: 84-84
- DOI
  10.1186/s40792-023-01665-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08910
[Journal Article] Predictive Model for Postoperative Ambulatory Function after Lower Extremity Bypass in Chronic Limb-Threatening Ischemia2021
- Author(s)
  Keisuke Miyake, Shinsuke Kikuchi, Takamitsu Tatsukawa, Daiki Uchida, Atsuhiro Koya, Yoshiki Sawa, Nobuyoshi Azuma
- Journal Title
  
  Ann Vasc Surg .
  
  Volume: 71 Pages: 321-330
- DOI
  10.1016/j.avsg.2020.07.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16380
[Journal Article] Inhibitory Effects of PRG4 on Migration and Proliferation of Human Venous Cells2020
- Author(s)
  Lei Wang, Shinsuke Kikuchi, Tannin A Schmidt, Max Hoofnagle, Thomas N Wight, Nobuyoshi Azuma, Gale L Tang, Michael Sobel, Gautum R Velamoor, Nahush A Mokadam, Richard D Kenagy
- Journal Title
  
  J Surg Res .
  
  Volume: 253 Pages: 53-62
- DOI
  10.1016/j.jss.2020.03.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16380
[Journal Article] <i>NT5E</i> Genetic Mutation Is a Rare But Important Cause of Intermittent Claudication and Chronic Limb-Threatening Ischemia2020
- Author(s)
  Azuma N, Uchida T, Kikuchi S, Sadahiro M, Shintani T, Yanagi K, Higashita R, Yamashita A, Makita Y, Kaname T.
- Journal Title
  
  Circ J
  
  Volume: 84 Issue: 7 Pages: 1183-1188
- DOI
  10.1253/circj.CJ-20-0153
- NAID
  130007864270
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2020-06-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09916, KAKENHI-PROJECT-18K16380
[Journal Article] Extracellular Vesicles Are Key Regulators of Tumor Neovasculature2020
- Author(s)
  Naoya Kuriyama, Yusuke Yoshioka, Shinsuke Kikuchi, Nobuyoshi Azuma, Takahiro Ochiya
- Journal Title
  
  Front Cell Dev Biol .
  
  Volume: 8 Pages: 611039-611039
- DOI
  10.3389/fcell.2020.611039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16380
[Journal Article] Collateral artery bypass in the infrapopliteal segment2020
- Author(s)
  Tochikubo A, Koya A, Uchida D, Tada Y, Kikuchi S, Azuma N.
- Journal Title
  
  J Vasc Surg Cases Innov Tech .
  
  Volume: 7 Issue: 1 Pages: 30-34
- DOI
  10.1016/j.jvscit.2020.12.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16380
[Journal Article] Development of gene therapy with a cyclic adenosine monophosphate response element decoy oligodeoxynucleotide to prevent vascular intimal hyperplasia2020
- Author(s)
  Uchida Daiki、Saito Yukihiro、Kikuchi Shinsuke、Yoshida Yuri、Hirata Satoshi、Sasajima Tadahiro、Azuma Nobuyoshi
- Journal Title
  
  Journal of Vascular Surgery
  
  Volume: 71 Issue: 1 Pages: 229-241
- DOI
  10.1016/j.jvs.2019.02.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16379, KAKENHI-PROJECT-18K16380
[Journal Article] Involvement of Extracellular Vesicles in Vascular-Related Functions in Cancer Progression and Metastasis2019
- Author(s)
  Kikuchi Shinsuke、Yoshioka Yusuke、Prieto-Vila Marta、Ochiya Takahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 10 Pages: 2584-2584
- DOI
  10.3390/ijms20102584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16380, KAKENHI-PROJECT-15H05791
[Journal Article] Effectiveness and Safety of Ultrasound Guided Lower Extremity Nerve Blockade in Infragenicular Bypass Grafting for High Risk Patients With Chronic Limb Threatening Ischaemia2019
- Author(s)
  Kikuchi Shinsuke、Yamaguchi Takuya、Miyake Keisuke、Uchida Daiki、Koya Atsuhiro、Iida Takafumi、Kurosawa Atsushi、Sasakawa Tomoki、Kunisawa Takayuki、Azuma Nobuyoshi
- Journal Title
  
  European Journal of Vascular and Endovascular Surgery
  
  Volume: 58 Issue: 2 Pages: 206-213
- DOI
  10.1016/j.ejvs.2019.03.023
- NAID
  40022289507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16380
[Journal Article] Smooth muscle cells of human veins show an increased response to injury at valve sites2018
- Author(s)
  Kikuchi Shinsuke、Chen Lihua、Xiong Kevin、Saito Yukihiro、Azuma Nobuyoshi、Tang Gale、Sobel Michael、Wight Thomas N.、Kenagy Richard D.
- Journal Title
  
  Journal of Vascular Surgery
  
  Volume: 67 Issue: 5 Pages: 1556-1570.e9
- DOI
  10.1016/j.jvs.2017.03.447
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19962
[Journal Article] mooth Muscle Cells of Human Veins Show An Increased Response to Injury at Valve Sites2017
- Author(s)
  Shinsuke Kikuchi, Lihua Chen, Kevin Xiong, Yukihiro Saito, Nobuyoshi Azuma, Gale Tang, Michael Sobel, Thomas N Wight, Richard D Kenagy
- Journal Title
  
  Journal of Vascular Surgery
  
  Volume: 未定
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19962
[Presentation] Human saphenous vein smooth muscle cells uptake extracellular vesicles from adeventitial cells2023
- Author(s)
  Shinsuke Kikuchi, Keisuke Kamada, Kazuki Takahashi, Yusuke Yoshioka, Takamitsu Tatsukawa, Naoya Kuriyama, Yuri Yoshida, Daiki Uchida, Richard D. Kenagy, Gale L Tang, Takahiro Ochiya, Nobuyoshi Azuma
- Organizer
  International Society of Extracellular Vesicles 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08910
[Presentation] Importance of Pedal Microcirculation to Wounds for Wound Healing After Bypass Surgery in Chronic Limb-threatening Ischemia2023
- Author(s)
  Keisuke Miyake, Shinsuke Kikuchi, Daiki Uchida, Shigeru Miyagawa, Nobuyoshi Azuma
- Organizer
  Vascular Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08910
[Presentation] Impact of Hemodynamic Success of Revascularization Measured by Skin Perfusion Pressure on Wound Healing in Chronic Limb-threatening Ischemia2023
- Author(s)
  Ying-Sheng Li, Shinsuke Kikuchi, Kazuki Takahashi, Keisuke Kamada, Yuri Yoshida, Daiki Uchida, and others
- Organizer
  Vascular Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08910
[Presentation] Importance of Limb Severity on Primary Graft Patency of Ipsilateral Single Saphenous Vein Grafts for Lower Extremity Artery Bypass in Chromic Limb-threatening Ischemia2023
- Author(s)
  Shinsuke Kikuchi
- Organizer
  Vascular Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08910
[Presentation] 大伏在静脈壁構成細胞内のコミュニケーションにおけるエクソソームの関与2022
- Author(s)
  菊地信介、竜川貴光、髙橋一輝、大平成真、栗山直也、吉田有里、内田大貴、吉岡祐亮、落谷孝広、東信良
- Organizer
  日本細胞外小胞学会2022
- Data Source
  KAKENHI-PROJECT-22K08910
[Presentation] Development of a biomarker for peripheral artery disease using extracellular vesicles associated miRNA2021
- Author(s)
  栗山直也、吉岡祐亮、菊地信介、東信良、落谷孝広
- Organizer
  International Society for Extracellular Vesicles 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08749
[Presentation] Pre-operative d-ROMs as a biomarker for predicting graft failure after distal bypass surgery in CLTI patients2020
- Author(s)
  Daiki.U，Kikuchi S, Uchida D, Kuriyama N, Takahashi K, Kamada K, Tatsukawa T, Tochikubo A, Yoshida Y, Koya A, Azuma N
- Organizer
  SVS 2020 Vascular Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08749
[Presentation] Possibility of Exosomal MicroRNAs Associated with Chronic Limb-Threatening Ischemia as a promising Biomarker2020
- Author(s)
  菊地信介、吉岡祐亮、栗山直也、吉田有里、大塚蔵嵩、山本雄介、東信良、落谷孝広
- Organizer
  International Society for Extracellular Vesicles 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08749
[Presentation] Possibility of >> Exosomal MicroRNAs Associated with Chronic Limb-Threatening Ischemia as a >> promising Biomarker2020
- Author(s)
  Shinsuke Kikuchi, Yusuke Yoshioka, Naoya Kuriyama, Yuri Yoshida, Kurataka Otsuka, Yusuke Yamamoto, Nobuyoshi Azuma, Takahiro Ochiya
- Organizer
  International Society for Extracellular Vesicles 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16380
[Presentation] Significance of Recovery of Limb Function after surgical revascularization in Chronic Limb-Threatening Ischemia2020
- Author(s)
  Kikuchi S, Uchida D, Kuriyama N, Takahashi K, Kamada K, Tatsukawa T, Tochikubo A, Yoshida Y, Koya A, Azuma N
- Organizer
  2020 Vascular Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16380
[Presentation] 末梢動脈疾患による重症下肢虚血におけるExosomal　microRNAによるスクリーニグモダリティとしての可能性2020
- Author(s)
  菊地信介、吉岡祐亮、栗山直也、吉田有里、東信良、落谷孝広
- Organizer
  第7回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-18K08749
[Presentation] Develpment of a biomarker for peripheral artery disease using extracellular vesicles associated miRNA2020
- Author(s)
  Naoya Kuriyama, Yusuke Yoshioka, Shinsuke Kikuchi, Nobuyoshi Azuma, Takahiro Ochiya
- Organizer
  International Society for Extracellular Vesicles 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16380
[Presentation] Factors Related to Postoperative Delirium in Vascular Surgery in an Aging Society2020
- Author(s)
  A. Tochikubo, S. Kikuchi, K. Takahashi, T. Tatsukawa, Y. Yoshida, D. Uchida, A. Koya, N. Azuma
- Organizer
  34th ESVS Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16380
[Presentation] 末梢動脈疾患による重症下肢虚血におけるExsomal microRNA　発現プロファイルから見たリキッドバイオプシーの可能性2020
- Author(s)
  菊地信介、吉岡祐亮、大塚蔵嵩、山本雄介、東信良、落谷孝広
- Organizer
  第4回Liquid　Biopsy　研究会
- Data Source
  KAKENHI-PROJECT-18K08749
[Presentation] A Change of Duplex Sonographic Velocities and Flow of Infrapopliteal Vein Graft in 30 Days After Surgery is a Strong Predictor for 1-year Graft Patency2019
- Author(s)
  Naoya Kuriyama, Shinsuke Kikuchi, Takamitsu Tatsukawa, Ai Tochikubo, Daiki Uchida, Atsuhiro Koya, Nobuyoshi Azuma
- Organizer
  ESVS Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16380
[Presentation] Prognostic Factors of Long-term Survivors After Surgical Revascularization in Dialysis-dependent Patients with Chronic Limb Threatening Ischemia2019
- Author(s)
  Shinsuke Kikuchi, Naoya Kuriyama, Ai Tochikubo, Daiki Uchida, Atsuhiro Koya, Tadahiro Sasajima, Nobuyoshi Azuma
- Organizer
  ESVS Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16380

1. UCHIDA DAIKI (80422038)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. Nobuyoshi Azuma (30250559)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 吉田有里 (50646057)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. 大平成真 (70899814)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 竜川貴光 (80837914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 古屋敦宏 (90463752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 齊藤幸裕 (80540583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KIKUCHI Shinsuke 菊地 信介

Research Projects

Research Products

Co-Researchers

静脈グラフト内膜肥厚における外膜細胞由来細胞外小胞の役割と外膜前駆細胞の重要性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

包括的高度慢性下肢虚血が与える自家静脈グラフトへの分子細胞学的影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遠赤外線照射による熱ショック蛋白を介した血管内膜肥厚抑制の機序解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of an animal method for controlling vein graft intimal thickening based on genetic analysis of clinical specimens

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of FIR therapy for suppressing vascular intimal hyperplasia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinical study of stem cell function in patients with peripheral arterial disease: Role of stem cell senescence in poor prognosis of patients.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and elucidating of function of cells involved with intimal hyperplasia in a valve site of vein graftPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of intimal hyperplasia development at valve site of human vein graftPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Super-Elderly Case of Acute Lower Limb Ischemia Treated with Indigo Aspiration System in Japan2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Venous Screening Activities at the Site of Hokkaido East Iburi Earthquake: Report from the Result of Venous Screening in Preventive Awareness Activities2023

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Giant Superior Mesenteric Artery Aneurysm Treated by Endovascular Treatment in a Very Elderly Female2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of lymphoma mimicking infected internal iliac artery aneurysm2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictive Model for Postoperative Ambulatory Function after Lower Extremity Bypass in Chronic Limb-Threatening Ischemia2021

Author(s)

KIKUCHI Shinsuke 菊地信介