YOSHIMI AKIHIDE 吉見昭秀

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YOSHIMI Akihide 吉見昭秀

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Researcher Number	80609016
Other IDs	https://orcid.org/0000-0002-0664-7281
Affiliation (Current)	2024: 国立研究開発法人国立がん研究センター, 研究所, 分野長
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人国立がん研究センター, 研究所, 分野長 2021 – 2022: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2016 – 2017: 東京大学, 医学部附属病院, 特任助教 2014 – 2015: 東京大学, 医学部附属病院, 助教 2013 – 2014: 東京大学, 医学部附属病院, 特任助教 2012: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 50010:Tumor biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / General internal medicine(including psychosomatic medicine) / Hematology Except Principal Investigator Hematology / Basic Section 56030:Urology-related / Basic Section 55020:Digestive surgery-related / Basic Section 62010:Life, health and medical informatics-related
Keywords	Principal Investigator がん / 核酸医薬 / スプライシング / ASO / 白血病 / iPS細胞 / イントロン保持 / Splicing / 質量分析 / RNA分解 … More / RNA結合蛋白質 / 神経膠腫 / RNA binding protein / Leukemia / Thymoma / Bladder carcinoma / Multi-omics analysis / Cancer / RNA splicing / 腫瘍生物学 / RNAスプライシング / 再生医療 / 好中球 / 細胞株化 / 化学療法 / サイトカイン / 顆粒球輸血 / 顆粒球輸注 / 白血病幹細胞 / トランスクリプト―ム / エピゲノム / エピゲノム解析 / 発現解析 / 標的遺伝子 / 慢性骨髄単球性白血病 / 急性骨髄性白血病 … More Except Principal Investigator 腫瘍合成致死 / 耐性 / がん / 化学放射線療法 / 発癌機構 / 大腸癌 / ゲノム変異 / スプライシング / クラウド / 大規模データ解析 / スプライシング異常 / 公共データ / トランスクリプトーム / 多能性幹細胞 / 人工多能性幹細胞 / 造血幹細胞 / iPS細胞 / アザシチジン / 耐性化メカニズム / shRNAライブラリ / 全エクソームシークエンシング / 抵抗性メカニズム / 骨髄異形成症候群 Less

scTranscriptome解析による難治性右側大腸癌の発癌機構の解明
- Principal Investigator
  
  向山順子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  International University of Health and Welfare
Understanding novel cell principle and cancer pathogenesis through comprehensive analysis of RNA degradationPrincipal Investigator
- Principal Investigator
  
  吉見昭秀
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Cancer Center Japan
RNA分解の時空間的解析科学の創生Principal Investigator
- Principal Investigator
  
  吉見昭秀
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  National Cancer Center Japan
スプライシング異常を伴うがんに対する新規核酸医薬治療法の開発Principal Investigator
- Principal Investigator
  
  吉見昭秀
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
Comprehensive understanding and novel therapeutic approaches for spliceosome mutant cancersPrincipal Investigator
- Principal Investigator
  
  吉見昭秀
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Cancer Center Japan
大規模トランスクリプトームからの自律的知能獲得システム基盤の開発
- Principal Investigator
  
  白石友一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  National Cancer Center Japan
Development of synthetic lethal approach for treating solid tumors that have progressed despite chemoradiation therapy.
- Principal Investigator
  
  小村和正
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Establishment of transplantable hematopoietic stem cells using human iPSCs
- Principal Investigator
  
  Taoka Kazuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Establishment of scientific basis for iPS cell-rerived granulocyte transfusion strategyPrincipal Investigator
- Principal Investigator
  
  Yoshimi Akihide
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  The University of Tokyo
Exploration of genes associated with efficacy of DNA methytransferase inhibitors for low risk MDS.
- Principal Investigator
  
  NANNYA Yasuhito
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Development of leukemia stem cell-specific therapy based on establishment of induced pluripotent stem cells derived from acute myeloid leukemia.Principal Investigator
- Principal Investigator
  
  YOSHIMI Akihide
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] mRNAの制御機構の解明と治療薬・ワクチンへの活用2023
- Author(s)
  西野貴大, 網代将彦, 吉見昭秀
- Total Pages
  411
- Publisher
  技術情報協会
- ISBN
  9784861049378
- Data Source
  KAKENHI-PROJECT-21H04828
[Book] RNA Therapeutics for Cancers2022
- Author(s)
  Michiko Kurikawa, Marimu Sakumoto and Akihide Yoshimi
- Total Pages
  24
- Publisher
  IntechOpen
- Data Source
  KAKENHI-PROJECT-21H04828
[Book] RNA Therapeutics for Cancers2022
- Author(s)
  Michiko Kurikawa, Marimu Sakumoto and Akihide Yoshimi
- Total Pages
  24
- Publisher
  IntechOpen
- Data Source
  KAKENHI-PROJECT-22KF0409
[Book] 『カラーテキスト血液病学第2版』2013
- Author(s)
  吉見昭秀、黒川峰夫（木崎昌弘編著）
- Total Pages
  688
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24790964
[Book] 『カラーテキスト血液病学第2 版』(in Japanese)第2 章D.骨髄系腫瘍の発症機構2013
- Author(s)
  吉見昭秀, 黒川峰夫
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Pathogenic Roles of RNA-Binding Proteins in Sarcomas2022
- Author(s)
  Hai Yu、Kawachi Asuka、He Xiaodong、Yoshimi Akihide
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 15 Pages: 3812-3812
- DOI
  10.3390/cancers14153812
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828, KAKENHI-PROJECT-22KF0409
[Journal Article] Systematic identification of intron retention associated variants from massive publicly available transcriptome sequencing data2022
- Author(s)
  Shiraishi Yuichi、Okada Ai、Chiba Kenichi、Kawachi Asuka、Omori Ikuko、Mateos Ra?l Nicol?s、Iida Naoko、Yamauchi Hirofumi、Kosaki Kenjiro、Yoshimi Akihide
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 5357-5357
- DOI
  10.1038/s41467-022-32887-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04828, KAKENHI-PROJECT-21H03549, KAKENHI-PROJECT-22KF0409
[Journal Article] Structural basis of cytokine-mediated activation of ALK family receptors2021
- Author(s)
  De Munck Steven、Provost Mathias、Kurikawa Michiko、Omori Ikuko、Mukohyama Junko、Felix Jan、Bloch Yehudi、Abdel-Wahab Omar、Bazan J. Fernando、Yoshimi Akihide、Savvides Savvas N.
- Journal Title
  
  Nature
  
  Volume: 600 Issue: 7887 Pages: 143-147
- DOI
  10.1038/s41586-021-03959-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828, KAKENHI-PROJECT-20K17687
[Journal Article] Physical interaction between BAALC and DBN1 induces chemoresistance in leukemia2021
- Author(s)
  Maki Hiroaki、Yoshimi Akihide、Shimada Takashi、Arai Shunya、Morita Ken、Kamikubo Yasuhiko、 Ikegawa Masaya、Kurokawa Mineo
- Journal Title
  
  Experimental Hematology
  
  Volume: 94 Pages: 31-36
- DOI
  10.1016/j.exphem.2020.12.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21538, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-20H02932, KAKENHI-PROJECT-21H04805, KAKENHI-PROJECT-21H04828
[Journal Article] Efficient production of human neutrophils from iPSCs that prevent murine lethal infection with immune cell recruitment.2021
- Author(s)
  Miyauchi M, Ito Y, Nakahara F, Hino T, Nakamura F, Iwasaki Y, Kawagoshi T, Koya J, Yoshimi A, Arai S, Kagoya Y, Kurokawa M
- Journal Title
  
  Blood
  
  Volume: 138 Issue: 24 Pages: 2555-2569
- DOI
  10.1182/blood.2021011576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04805, KAKENHI-PROJECT-21H04828
[Journal Article] Aberrant RNA splicing and therapeutic opportunities in cancers2021
- Author(s)
  Yamauchi Hirofumi、Nishimura Kazuki、Yoshimi Akihide
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 2 Pages: 373-381
- DOI
  10.1111/cas.15213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04828
[Journal Article] Loss-of-function mutations in BCOR contribute to chemotherapy resistance in acute myeloid leukemia.2021
- Author(s)
  Honda A, Koya J, Yoshimi A, Miyauchi M, Taoka K, Kataoka K, Arai S, Kurokawa M.
- Journal Title
  
  Experimental Hematology
  
  Volume: - Pages: 42-48.e11
- DOI
  10.1016/j.exphem.2021.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21538, KAKENHI-PROJECT-21H04805, KAKENHI-PROJECT-21H04828
[Journal Article] Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia.2014
- Author(s)
  Sato T, Goyama S, Kataoka K, Nasu R, Tsuruta-Kishino T, Kagoya Y, Nukina A, Kumagai K, Kubota N, Nakagawa M, Arai S, Yoshimi A, Honda H, Kadowaki T, Kurokawa M.
- Journal Title
  
  Oncogene
  
  Volume: 33 Issue: 42 Pages: 5028-5038
- DOI
  10.1038/onc.2014.108
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-24790962, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-26670464, KAKENHI-PROJECT-26860474, KAKENHI-PROJECT-26860721
[Journal Article] 白血病幹細胞とclonal evolution2014
- Author(s)
  吉見昭秀, 黒川峰夫
- Journal Title
  
  日本臨牀
  
  Volume: 72 Pages: 1012-1017
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] AML の予後を規定する遺伝子発現2014
- Author(s)
  吉見昭秀
- Journal Title
  
  血液内科
  
  Volume: 68 Pages: 267-272
- NAID
  40020006999
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Recurrent CDC25C mutations drive malignant transformation in FPD/AML2014
- Author(s)
  Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, Nakagawa M, Nannya Y, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Ichikawa M, Mano H, Kurokawa M
- Journal Title
  
  Nature communications
  
  Volume: 5 Issue: 1 Pages: 4770-4770
- DOI
  10.1038/ncomms5770
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24390268, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670482, KAKENHI-PROJECT-25830139, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-26461598, KAKENHI-PROJECT-26860474
[Journal Article] Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16.2014
- Author(s)
  Ueda K, Yoshimi A, Kagoya Y, Nishikawa S, Marquez VE, Nakagawa M, Kurokawa M.
- Journal Title
  
  Cancer Science
  
  Volume: （in press） Issue: 5 Pages: 0-0
- DOI
  10.1111/cas.12386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-24890045, KAKENHI-PROJECT-26860474
[Journal Article] Development of hairy cell leukemia in familial platelet disorder with predisposition to acute myeloid leukemia.2014
- Author(s)
  Toya T, Yoshimi A, Morioka T, Arai S, Ichikawa M, Usuki K, Kurokawa M
- Journal Title
  
  Platelets
  
  Volume: 25 Issue: 4 Pages: 300-302
- DOI
  10.3109/09537104.2013.818636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02699, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26860474
[Journal Article] JAK2V617F+ myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2.2014
- Author(s)
  Kagoya Y, Yoshimi A, Tsuruta-Kishino T, Arai S, Satoh T, Akira S, Kurokawa M.
- Journal Title
  
  Blood
  
  Volume: 124 Issue: 19 Pages: 2996-3006
- DOI
  10.1182/blood-2014-04-570572
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-25893047, KAKENHI-PROJECT-26860474
[Journal Article] EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis.2014
- Author(s)
  Tanaka M, Suzuki HI, Shibahara J, Kunita A, Isagawa T, Yoshimi A, Kurokawa M, Miyazono K, Aburatani H, Ishikawa S, Fukayama M.
- Journal Title
  
  Oncogene
  
  Volume: 33(19) Issue: 19 Pages: 2454-63
- DOI
  10.1038/onc.2013.204
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134003, KAKENHI-PROJECT-24689018, KAKENHI-PROJECT-25860263, KAKENHI-PROJECT-25860289, KAKENHI-PROJECT-26860474
[Journal Article] NF-・B/TNF- positive feedback loop with active proteasome machinery supports myeloid leukemia initiating cell capacity2014
- Author(s)
  Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 124 Pages: 528-42
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.2014
- Author(s)
  Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M.
- Journal Title
  
  J Clin Invest.
  
  Volume: 124 Issue: 2 Pages: 528-542
- DOI
  10.1172/jci68101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-26860474
[Journal Article] ゲノム創薬時代の血液疾患分子標的薬の研究2014
- Author(s)
  吉見昭秀, 黒川峰夫
- Journal Title
  
  日本臨牀
  
  Volume: 72 Pages: 1005-1011
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukaemia.2013
- Author(s)
  Nukina A, Kagoya Y, Watanabe-Okochi N, Arai S, Ueda K, Yoshimi A, Nannya Y, and Kurokawa M.
- Journal Title
  
  Br J Haematol
  
  Volume: In Press Issue: 3 Pages: 580-91
- DOI
  10.1111/bjh.12726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790961, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26860474
[Journal Article] The shortest isoform of C/EBP・・ Liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model2013
- Author(s)
  Watanabe-Okochi N, Yoshimi A, Sato T, Ikeda T, Kumano K, Taoka K, Satoh Y, Shinohara A, Tsuruta T, Masuda A, Yokota H, Yatomi Y, Takahashi K, Kitaura J, Kitamura T, Kurokawa M
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 54 Pages: 749-58
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Treatment with azacitidine for myelodysplastic syndrome transformed from essential thrombocythemia2013
- Author(s)
  Iizuka H, Yoshimi A, Yamamoto G, Masuda A, Nannya Y, Ichikawa M, Yatomi Y, Kurokawa M
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 54 Pages: 468-72
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Successful allogeneic stem cell transplantation for Lennert lymphoma2013
- Author(s)
  Uni M, Yoshimi A, Nakamura F, Takazawa Y, Fukayama M, Kurokawa M
- Journal Title
  
  Annals of Hematology
  
  Volume: 92 Pages: 859-60
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP) , collaborates with Evi1 to induce AML in a mouse BMT model2013
- Author(s)
  Okochi, N., Yoshimi, A., Sato, T., Ikeda, T., Kumano, K., Taoka, K., Sato, Y., Shinohara, A., Tsuruta, A., Masuda, A., Yokota, H., Yatomi, Y., Takahashi, K., Kitaura, J., Kitamura, T. and Kurokawa, M
- Journal Title
  
  Blood
  
  Volume: 121 Issue: 20 Pages: 4142-4155
- DOI
  10.1182/blood-2011-07-368654
- NAID
  10031196292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24659457, KAKENHI-PROJECT-24790961, KAKENHI-PROJECT-24790964, KAKENHI-PUBLICLY-23130503
[Journal Article] The shortest isoform of C/EBP・, Liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model2013
- Author(s)
  Watanabe-Okochi N, Yoshimi A, Sato T, Ikeda T, Kumano K, Taoka K, Satoh Y, Shinohara A, Tsuruta T, Masuda A, Yokota H, Yatomi Y, Takahashi K, Kitaura J, Kitamura T, Kurokawa M
- Journal Title
  
  Blood
  
  Volume: 121 Pages: 4142-55
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Successful treatment with recombinant thrombomodulin for B-cell lymphomaassociated hemophagocytic syndrome complicated by disseminated intravascular coagulation2013
- Author(s)
  Uni M, Yoshimi A, Maki H, Maeda D, Nakazaki K, Nakamura F, Fukayama M, Kurokawa M
- Journal Title
  
  International Journal of Clinical and Experimental Pathology
  
  Volume: 6 Pages: 1190-4
- NAID
  120007089059
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] 鉄欠乏性貧血の雑学2013
- Author(s)
  吉見昭秀
- Journal Title
  
  Medical Practice
  
  Volume: 30 Pages: 896-896
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Unique association of Waldenström macroglobulinemia with optic neuritis and monoclonal T-cell expansion2013
- Author(s)
  Morita K, Yoshimi A, Masuda A, Ichikawa M, Yatomi H, Kurokawa M
- Journal Title
  
  International Journal of Hematology
  
  Volume: 98 Pages: 247-9
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] A role for RUNX1 in hematopoiesis and myeloid leukemia.2013
- Author(s)
  Ichikawa M, Yoshimi A, Nakagawa M, Nishimoto N, Watanabe-Okochi N, and Kurokawa M.
- Journal Title
  
  Int J Hematol
  
  Volume: 97 Issue: 6 Pages: 726-734
- DOI
  10.1007/s12185-013-1347-3
- NAID
  10031183728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25670445
[Journal Article] A Role for RUNX1 in Hematopoiesis and Myeloid Leukemia2013
- Author(s)
  Ichikawa M, Yoshimi A, Nakagawa M, Nishimoto N, Watanabe-Okochi N, Kurokawa M
- Journal Title
  
  International Journal of Hematology
  
  Volume: 97 Pages: 726-34
- NAID
  10031183728
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Transformation of follicular lymphoma in the retroperitoneal muscles demonstrated by CT-guided needle biopsy of FDG-avid lesions; case series2013
- Author(s)
  Uni M, Nakamura F, Yoshimi A, Shinozaki-Ushiku A, Hosoi A, Nakazaki K, Nannya Y, Fukayama M, Kurokawa M
- Journal Title
  
  International Journal of Clinical and Experimental Pathology
  
  Volume: 7 Pages: 402-6
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] 難治性AML の遺伝子発現プロファイル2012
- Author(s)
  吉見昭秀
- Journal Title
  
  血液内科
  
  Volume: 65 Pages: 665-669
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] 正常核型急性骨髄性白血病における遺伝子変異とその意義2012
- Author(s)
  吉見昭秀, 黒川峰夫
- Journal Title
  
  Medical Practice
  
  Volume: 29 Pages: 1295-1298
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] 白血病がん遺伝子Evi1 を介したエピゲノム異常とシグナル異常2012
- Author(s)
  吉見昭秀
- Journal Title
  
  血液内科
  
  Volume: 64 Pages: 179-184
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Efficacy of pleural biopsy for diagnosis of pleural effusion due to chronic GVHD after hematopoietic stem cell transplantation2012
- Author(s)
  Miyauchi M, Yoshimi A, Nannya Y, Takazawa Y, Ichikawa M, Fukayama M, Kurokawa M
- Journal Title
  
  International Journal of Hematology
  
  Volume: 96 Pages: 146-8
- NAID
  10030954843
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Hepatocellular carcinoma in cirrhotic liver with graft-versus-host disease2012
- Author(s)
  Yoshimi A, Yamamoto G, Goto T, Fukayama M, Kurokawa M
- Journal Title
  
  Annals of Hematology
  
  Volume: 91 Pages: 1501-2
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] 難治性AML における遺伝子発現異常2012
- Author(s)
  吉見昭秀, 黒川峰夫
- Journal Title
  
  最新医学
  
  Volume: 67 Pages: 2466-2471
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Development of hairy cell leukemia in familial platelet disorder with predisposition to acute myeloid leukemia
- Author(s)
  Toya T, Yoshimi A, Morioka T, Arai S, Ichikawa M, Usuki K, Kurokawa M
- Journal Title
  
  Platelets
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Evi1 Defines Leukemia-initiating Capacity and Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia
- Author(s)
  Sato T, Goyama S, Kataoka K, Nasu R, Tsuruta-Kishino T, Kagoya Y, Nukina A, Kumagai K, Kubota N, Nakagawa M, Arai S, Yoshimi A, Honda H, Kadowaki T, Kurokawa M
- Journal Title
  
  Oncogene
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Safety of high-dose micafungin for patients with hematological diseases
- Author(s)
  Yamazaki S, Nakamura F, Yoshimi A, Ichikawa M, Nannya Y, Kurokawa M
- Journal Title
  
  Leukemia & Lymphoma
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of MLL fusion leukemia through up-regulation of p16
- Author(s)
  Ueda K, Yoshimi A, Kagoya Y, Nishikawa S, Marquez V, Nakagawa M, Kurokawa M
- Journal Title
  
  Cancer Science
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukaemia
- Author(s)
  Nukina A, Kagoya Y, Watanabe-Okochi N, Arai S, Ueda K, Yoshimi A, Nannya Y, Kurokawa M
- Journal Title
  
  British Journal of Haematology
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790964
[Journal Article] EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis
- Author(s)
  Tanaka M, Suzuki HI, Shibahara J, Kunita A, Isagawa T, Yoshimi A, Kurokawa M, Miyazono K, Aburatani H, Ishikawa S, Fukayama M
- Journal Title
  
  Oncogene
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Targeting Splicing-Associated Variants in Leukemias2023
- Author(s)
  Akihide Yoshimi
- Organizer
  2023 Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies Symposium(
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0409
[Presentation] がんのスプライシング異常を標的とした治療法探索2023
- Author(s)
  吉見昭秀
- Organizer
  第47回セルセラピーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] RNAスプライシング異常を標的としたがん治療法2023
- Author(s)
  吉見昭秀
- Organizer
  超異分野学会東京大会2023基調講演
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] RNAスプライシング異常を標的としたがん治療法2023
- Author(s)
  吉見昭秀
- Organizer
  超異分野学会東京大会2023基調講演
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0409
[Presentation] がんにおけるRNA生物学の理解と治療法の探索2023
- Author(s)
  吉見昭秀
- Organizer
  第70回よこはまNMR研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Targeting Splicing-Associated Variants in Leukemias2023
- Author(s)
  吉見昭秀
- Organizer
  2023 Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] RNAスプライシング異常からがんを理解する2023
- Author(s)
  吉見昭秀
- Organizer
  第3回SAMURAI研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] 次世代核酸医薬による新規がん治療法の展開2022
- Author(s)
  吉見昭秀
- Organizer
  BioJapan 2022
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Coordinated Alterations in RNA Splicing and Epigenome in Cancers2022
- Author(s)
  Akihide Yoshimi
- Organizer
  第81回日本癌学会学術総会 International session(
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0409
[Presentation] がんのRNAスプライシング異常2022
- Author(s)
  吉見昭秀
- Organizer
  第一三共株式会社オンコロジー研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Understanding and Targeting Aberrant RNA Splicing in Leukemias2022
- Author(s)
  吉見昭秀
- Organizer
  The 8th Canadian Conference on Epigenetics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] RNAスプライシング異常を標的にした治療戦略2022
- Author(s)
  吉見昭秀
- Organizer
  第10回Cancer Stem Cell Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] 遺伝子変異に起因する RNA スプライシング異常から紐解く発がんメカニズム2022
- Author(s)
  吉見昭秀
- Organizer
  第51回日本環境変異原ゲノム学会年次大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Understanding and Targeting Aberrant RNA Splicing in Leukemias2022
- Author(s)
  吉見昭秀
- Organizer
  第81回日本癌学会学術総会 JCA-Mauveynay Award Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Aberrant RNA splicing in hematologic malignancies2022
- Author(s)
  Akihide Yoshimi
- Organizer
  The 84th Japanese Society of Hematology Annual Meeting Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0409
[Presentation] がんのRNAスプライシング異常2022
- Author(s)
  吉見昭秀
- Organizer
  愛知県がんセンター研究所招聘セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] 造血器腫瘍のRNAスプライシングスプライシング異常を起点にした治療法2022
- Author(s)
  吉見昭秀
- Organizer
  第17回北関東小児セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] 次世代核酸医薬による新規がん治療法の展開2022
- Author(s)
  吉見昭秀
- Organizer
  BioJapan 2022
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0409
[Presentation] Aberrant RNA Splicing and Alterations in Epigenome Coordinately Drive Tumorigenesis2022
- Author(s)
  吉見昭秀
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] 白血病におけるスプライシング異常による病態理解と治療法開発2022
- Author(s)
  吉見昭秀
- Organizer
  第81回日本癌学会学術総会モーニングレクチャー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] がん横断的解析から理解するスプライシング異常2022
- Author(s)
  吉見昭秀
- Organizer
  令和3年度国際がん研究シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] がん横断的解析から理解するスプライシング異常2022
- Author(s)
  Yoshimi A
- Organizer
  令和3年度国際がん研究シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] 遺伝子変異に起因する RNA スプライシング異常から紐解く発がんメカニズム2022
- Author(s)
  吉見昭秀
- Organizer
  第51回日本環境変異原ゲノム学会年次大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0409
[Presentation] Understanding and Targeting Aberrant RNA Splicing in Leukemias2022
- Author(s)
  Akihide Yoshimi
- Organizer
  The 8th Canadian Conference on Epigenetics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0409
[Presentation] RNAスプライシング異常からがんを理解する2022
- Author(s)
  吉見昭秀
- Organizer
  MSD Urology Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Coordinated Alterations in RNA Splicing and Epigenome in Cancers2022
- Author(s)
  吉見昭秀
- Organizer
  第81回日本癌学会学術総会 International session
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Understanding and Targeting Aberrant Splicing in Leukemias2022
- Author(s)
  Yoshimi A
- Organizer
  4.The 1st JCA-AACR Precision Cancer Medicine International Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] RNAスプライシング異常から理解するがんの病態と治療法の開発2022
- Author(s)
  吉見昭秀
- Organizer
  第159回小児血液・腫瘍・免疫懇話会特別講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Aberrant RNA splicing in hematologic malignancies2022
- Author(s)
  吉見昭秀
- Organizer
  The 84th Japanese Society of Hematology Annual Meeting Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Understanding and Targeting Aberrant Splicing in Cancers2021
- Author(s)
  Yoshimi A
- Organizer
  5.The 39th Sapporo International Cancer Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] 米国東海岸留学のすすめ2021
- Author(s)
  吉見昭秀
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Mutant IDH1 promotes aberrant splicing in gliomas2021
- Author(s)
  Michiko Kuirkawa, Kuan-Ting Lin, Takaki Omura, Ikuko Omori, Hirofumi Yamauchi, Hanako Nakamura, Xiaohui Song, Atsuro Oishi, Adrian R. Krainer, Yoshitaka Narita, Akihide Yoshimi
- Organizer
  The 39th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Mutations in the RNA Splicing Factor SF3B1 Target PPP2R5A to Promote Tumorigenesis through MYC Stabilization2021
- Author(s)
  Hirofumi Yamauchi, Zhaoqi Liu, Michiko Kurikawa, Ikuko Omori, Xiaohui Song, Hanako Nakamura, Hana Cho, Lillian Bitner, Bo Liu, Atsuro Oishi, Anthony R. Mato, Peter Ruvolo, Giulia Fabbri, Laura Pasqualucci, Omar Abdel-Wahab, Raul Rabadan, Akihide Yoshimi
- Organizer
  The 39th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Healthcare workers’ attitudes toward COVID-19 mRNA vaccine technology: a nation-wide cross-sectional survey from Croatia2021
- Author(s)
  Tomislav Mestrovic, Simona Hren, Chirag Raval, Xiaodong He, Akihide Yoshimi
- Organizer
  The 19th International mRNA Health Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04828
[Presentation] Recurrent CDC25C mutations drive malignant transformation in FPD/AML2014
- Author(s)
  Akihide Yoshimi, Takashi Toya, Masahito Kawazu, Toshihide Ueno, Ayato Tsukamoto, Hiromitsu Iizuka, Masahiro Nakagawa, Yasuhito Nannya, Shunya Arai, Motoshi Ichikawa, Hironori Harada, Kensuke Usuki, Yasuhide Hayashi, Etsuro Ito, Keita Kirito, Hideaki Nakajima, Hiroyuki Mano, Mineo Kurokawa
- Organizer
  American Association for Cancer Research 2014
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Evi1 Defines Leukemia-initiating Capacity and Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia2014
- Author(s)
  Tomohiko Sato, Susumu Goyama, Keisuke Kataoka, Ryo Nasu, Takako Tsuruta-Kishino, Yuki Kagoya, Arika Nukina, Katsuyoshi Kumagai, Naoto Kubota, Masahiro Nakagawa, Shunya Arai, Akihide Yoshimi, Hiroaki Honda, Takashi Kadowaki and Mineo Kurokawa
- Organizer
  AACR 2014
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] JAK2V617F Mutation Evokes Paracrine DNA Damage To Adjacent Normal Cells Via Secretion Of Lipocalin-22013
- Author(s)
  Yuki Kagoya, Shunya Arai, Akihide Yoshimi, Takako Tsuruta-Kishino1, Keisuke Kataoka and Mineo Kurokawa
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] 発難治性T細胞リンパ腫にに対するmodified ESHAP療法の後方視的検討2013
- Author(s)
  木暮泰寛, 吉見昭秀, 植田航希, 南谷泰仁, 市川幹, 中村文彦, 黒川峰夫
- Organizer
  第53回リンパ網内系学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Modified ESHAP regimen for relapsed/refractory T-cell lymphoma : A retrospective analysis2013
- Author(s)
  木暮泰寛, 吉見昭秀, 植田航希, 南谷泰仁, 市川幹, 中村文彦, 黒川峰夫
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] NF-kB/TNF-a positive feedback loop with active proteasome system controls leukemia stem cell capacity2013
- Author(s)
  Yuki Kagoya, Akihide Yoshimi, Keisuke Kataoka, Masahiro Nakagawa, Keiki Kumano, Shunya Arai, Mineo Kurokawa
- Organizer
  Keystone Symposia Stem Cell Regulation in Homeostasis and Disease
- Place of Presentation
  Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation2013
- Author(s)
  Akihide Yoshimi, Takashi Toya, Masahiro Nakagawa, Masahito Kawazu, Yasuhito Nannya, Motoshi Ichikawa, Shunya Arai, Hironori Harada, Kensuke Usuki, Yasuhide Hayashi, Etsuro Ito, Keita Kirito, Hideaki Nakajima, Hiroyuki Mano, Mineo Kurokawa
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  New orleans, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Exome sequencing combined with single cell sequencing reveals genetic mechanisms of malignant transformation in FPD/AML2013
- Author(s)
  吉見昭秀、遠矢嵩、飯塚浩光、荒井俊也、中川正宏、河津正人、市川幹、桐戸敬太、間野博行、黒川峰夫
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Constitutive NF-kB activation maintained by autocrine TNF-a signaling and active proteasome system supports leukemia stem cell capacity2013
- Author(s)
  Yuki Kagoya, Akihide Yoshimi, Keisuke Kataoka, Masahiro Nakagawa, Kumano Keiki, Shunya Arai, Mineo Kurokawa
- Organizer
  The 11th Stem Cell Research Symposium
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] 家族性血小板異常症の病態解析2013
- Author(s)
  吉見昭秀、飯塚浩光、間野博行、荒井俊也、黒川峰夫
- Organizer
  造血器腫瘍研究会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Clonal and mutational evolution reveals genetic mechanisms of leukemia transformation of FPD/AML2013
- Author(s)
  吉見昭秀、遠矢嵩、飯塚浩光、荒井俊也、中川正宏、河津正人、市川幹、桐戸敬太、間野博行、黒川峰夫
- Organizer
  日本血液学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Clonal and mutational evolution reveals genetic mechanisms of leukemia transformation of FPD/AML2013
- Author(s)
  吉見昭秀, 遠矢嵩, 飯塚浩光, 荒井俊也, 中川正宏, 河津正人, 市川幹, 桐戸敬太, 間野博行, 黒川峰夫
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] JAK2V617F mutation evokes paracrine DNA damage to adjacent cells and drives leukemic transformation2013
- Author(s)
  籠谷勇紀, 吉見昭秀, 鶴田貴子, 片岡圭亮, 荒井俊也, 黒川峰夫
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Pathological analysis of familial platelet disorder with propensity to myeloid malignancy2013
- Author(s)
  Akihide Yoshimi, Hiromitsu Iizuka, Takashi Toya, Tomohiko Sato, Masahito Kawazu, Keiki Kumano, Motoshi Ichikawa, Keita Kirito, Hiroyuki Mano, Shunya Arai, Mineo Kurokawa
- Organizer
  RUNX Workshop
- Place of Presentation
  Wilsede, Germany
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] EZH2 targeting as a therapeutic strategy against MLL fusion leukemia stem cell2013
- Author(s)
  Koki Ueda, Akihide Yoshimi, Masahiro Nakagawa, Satoshi Nishikawa, Keiki Kumano, and Mineo Kurokawa
- Organizer
  Keystone Symposia Stem Cell Regulation in Homeostasis and Disease
- Place of Presentation
  Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Adiponectin promotes proliferation of hematopoietic cells in vivo2013
- Author(s)
  Yosuke Masamoto, Shunya Arai, Tomohiko Sato, Akihide Yoshimi, Iseki Takamoto, Naoto Kubota, Takashi Kadowaki, Mineo Kurokawa
- Organizer
  The 11th Stem Cell Research Symposium
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Anti-Obese Hormone Adiponectin Regulates Emergency Hematopoiesis and Antibacterial Response Through Downregulation Of Socs3 In Hematopoietic Progenitor Cells2013
- Author(s)
  Yosuke Masamoto, Shunya Arai, Tomohiko Sato, Akihide Yoshimi, Iseki Takamoto, Naoto Kubota, Takashi Kadowaki and Mineo Kurokawa
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Exome sequencing combined with single cell sequencing reveals genetic mechanisms of malignant transformation in FPD/AML2013
- Author(s)
  Akihide Yoshimi, Takashi Toya, Hiromitsu Iizuka, Shunya Arai, Masahiro Nakagawa, Masahito Kawazu, Motoshi Ichikawa, KeitaKirito, Hiroyuki Mano, Mineo Kurokawa
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Single-cell gene expression analysis reveals clonal architecture of blast-phase chronic myeloid leukemia2013
- Author(s)
  貫名有香, 籠谷勇紀, 大河内直子, 植田航希, 吉見昭秀, 南谷泰仁, 荒井俊也, 黒川峰夫
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Identification of miRNA targeting Evi12013
- Author(s)
  山本春菜, 横山和明, 呂軍, 大庭成喜, 川俣豊隆, 吉見昭秀, 森下和広, 黒川峰夫, 幸谷愛
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] 家族性血小板異常症の病態解析2013
- Author(s)
  飯塚浩光, 吉見昭秀, 間野博行, 荒井俊也, 黒川峰夫
- Organizer
  第17回造血器腫瘍研究会
- Place of Presentation
  宮崎
- Year and Date
  2013-02-02
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] A Randomized Controlled Study Evaluating The Efficacy Of Aprepitant For Highly Emetogenic Chemotherapies In Hematological Malignancies2013
- Author(s)
  Ryo Nasu, Yasuhito Nannya, Akihide Yoshimi, Masataka Hosoi, Kouki Ueda, Yumiko Yoshiki, Shunya Arai, Akihito Shinohara, Fumihiko Nakamura and Mineo Kurokawa
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Adiponectin promotes proliferation of hematopoietic cells in vivo2013
- Author(s)
  正本庸介, 荒井俊也, 佐藤智彦, 吉見昭秀, 高本偉碩, 窪田直人, 門脇孝, 黒川峰夫
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation2013
- Author(s)
  Akihide Yoshimi, Takashi Toya, Masahiro Nakagawa, Masahito Kawazu, Yasuhito Nannya, Motoshi Ichikawa, Shunya Arai, Hironori Harada, Kensuke Usuki, Yasuhide Hayashi, Etsuro Ito, Keita Kirito, Hideaki Nakajima, Hiroyuki Mano and Mineo Kurokawa
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Pathological analysis of familial platelet disorder with propensity to myeloid malignancy2013
- Author(s)
  Akihide Yoshimi, Hiromitsu Iizuka, Takashi Toya, Tomohiko Sato, Masahito Kawazu, Keiki Kumano, Motoshi Ichikawa, Keita Kirito, Hiroyuki Mano, Shunya Arai, Mineo Kurokawa
- Organizer
  Runx Workshop 2013
- Place of Presentation
  Wilsede, Germany
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] JAK2V617F mutation evokes paracrine DNA damage to adjacent cells and drives leukemic transformation2013
- Author(s)
  Yuki Kagoya, Akihide Yoshimi, Takako Tsuruta-Kishino, Keisuke Kataoka, Shunya Arai, Mineo Kurokawa
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] TNFa の自己分泌能と高いプロテアソーム活性によるNF-kB の恒常的活性化が骨髄性白血病幹細胞の増殖に重要な役割を担う2013
- Author(s)
  籠谷勇紀, 吉見昭秀, 黒川峰夫
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] NF-κB/TNF-α Positive Feedback Loop with Active Proteasome Machinery Supports Myeloid Leukemia Initiating Cell Capacity2012
- Author(s)
  Yuki Kagoya, Akihide Yoshimi, Shunya Arai, Keisuke Kataoka, Masahiro Nakagawa, Keiki Kumano and Mineo Kurokawa
- Organizer
  54th ASH Annual Meeting and Exposition
- Place of Presentation
  Atlanta, GA, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Identification of microRNAs targeting Evi-12012
- Author(s)
  Jun Lu1 Shigeyoshi Oba, Akihide Yoshimi, Kiyoshi Ando, Kazuhiro Morishita, Mineo Kurokawa, Ai Kotani
- Organizer
  第74回日本血液学会総会
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] NF-kB-TNF-a positive feedback loop is universally essential for maintenance of myeloid leukemia stem cells2012
- Author(s)
  Yuki Kagoya, Akihide Yoshimi, Shunya Arai, Masahiro Nakagawa, Keiki Kumano, Mineo Kurokawa
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] The histone methyltransferase EZH2 plays a crucial role in MLL-related leukemia2012
- Author(s)
  Koki Ueda, Akihide Yoshimi, Masahiro Nakagawa, Satoshi Nishikawa, Keiki Kumano, Mineo Kurokawa
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Evi1はポリコーム複合体との相互作用を介してエピジェネティックにPTEN の発現を抑制し, AKT/mTOR シグナルを活性化する2012
- Author(s)
  吉見昭秀, 合山進, 渡辺-大河内直子, 吉識由美子, 南谷泰仁, 仁田英里子, 荒井俊也, 佐藤智彦, 島辺宗健, 中川正宏, 今井陽一, 北村俊雄, 黒川峰夫
- Organizer
  第8回血液学若手研究者勉強会(麒麟塾)
- Place of Presentation
  品川
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Inhibition of EZH2 Depletes MLL Fusion Leukemia Stem Cells Through Restoration of p16 Expression2012
- Author(s)
  Koki Ueda, Akihide Yoshimi, Masahiro Nakagawa, Satoshi Nishikawa, Victor E Marquez, Keiki Kumano and Mineo Kurokawa
- Organizer
  54th ASH Annual Meeting and Exposition
- Place of Presentation
  Atlanta, GA, USA
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] The histone methyltransferase EZH2 plays a crucial role in MLL-related leukemia2012
- Author(s)
  Koki Ueda, Akihide Yoshimi, Masahiro Nakagawa, Satoshi Nishikawa, Keiki Kumano, Mineo Kurokawa
- Organizer
  第74回日本血液学会総会
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] NF-kB-TNF-a positive feedback loop is essential for maintenance of myeloid leukemia stem cells2012
- Author(s)
  Yuki Kagoya, Akihide Yoshimi, Shunya Arai, Masahiro Nakagawa, Keiki Kumano, Mineo Kurokawa
- Organizer
  第74回日本血液学会総会
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24790964
[Presentation] Modeling chronic myelomonocytic leukemia through patient-derived induced pluripotent stem cells
- Author(s)
  Kazuki Taoka, Shunya Arai, Masataka Hosoi, Fumihiko Nakamura, Masashi Miyauchi, Sho Yamazaki, Akira Honda, Takashi Kobayashi, Keisuke Kataoka, Keiki Kumano, Akihide Yoshimi, Koji Eto, Hiromitsu Nakauchi, Tatsutoshi Nakahara, Mineo Kurokawa
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26860474
[Presentation] Modeling chronic myelomonocytic leukemia through patient-derived induced pluripotent stem cells
- Author(s)
  Kazuki Taoka, Shunya Arai, Masataka Hosoi, Fumihiko Nakamura, Masashi Miyauchi, Sho Yamazaki, Akira Honda, Takashi Kobayashi, Keisuke Kataoka, Keiki Kumano, Akihide Yoshimi, Koji Eto, Hiromitsu Nakauchi, Tatsutoshi Nakahara, Mineo Kurokawa
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860474
[Presentation] Recurrent CDC25C mutations drive malignant transformation in FPD/AML
- Author(s)
  Akihide Yoshimi, Takashi Toya, Masahito Kawazu, Toshihide Ueno, Ayato Tsukamoto, Hiromitsu Iizuka, Masahiro Nakagawa, Yasuhito Nannya, Shunya Arai, Motoshi Ichikawa, Hironori Harada, Kensuke Usuki, Yasuhide Hayashi, Etsuro Ito, Keita Kirito, Hideaki Nakajima, Hiroyuki Mano, Mineo Kurokawa
- Organizer
  American Association for Cancer Research
- Place of Presentation
  San Diego、USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26860474
[Presentation] Generation of iPSC from primary CML patient samples
- Author(s)
  Akihide Yoshimi, Masashi Miyauchi, Tomohiko Sato, Keiki Kumano, Mineo Kurokawa
- Organizer
  16th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy
- Place of Presentation
  Philadelphia、USA
- Year and Date
  2014-09-04 – 2014-09-07
- Invited
- Data Source
  KAKENHI-PROJECT-26860474

1. NANNYA Yasuhito (60451811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Taoka Kazuki (30529178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 荒井俊也 (00579716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 白石友一 (70516880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 飯田直子 (40360557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 向山順子 (70734987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小村和正 (10789853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 辻川和丈 (10207376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 東治人 (40231914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 谷口高平 (70779686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松井佑介 (90761495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUKAMOTO Ayato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AILIKEN GUZHANUER

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HARADA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 黒川峰夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
16. 北村俊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 北浦次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 原田浩徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 石川俊平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 熊野恵城

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIMI AKIHIDE 吉見 昭秀

YOSHIMI Akihide 吉見 昭秀

Research Projects

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Co-Researchers

scTranscriptome解析による難治性右側大腸癌の発癌機構の解明

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Understanding novel cell principle and cancer pathogenesis through comprehensive analysis of RNA degradationPrincipal Investigator

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RNA分解の時空間的解析科学の創生Principal Investigator

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スプライシング異常を伴うがんに対する新規核酸医薬治療法の開発Principal Investigator

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Comprehensive understanding and novel therapeutic approaches for spliceosome mutant cancersPrincipal Investigator

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大規模トランスクリプトームからの自律的知能獲得システム基盤の開発

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Development of synthetic lethal approach for treating solid tumors that have progressed despite chemoradiation therapy.

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Establishment of transplantable hematopoietic stem cells using human iPSCs

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Establishment of scientific basis for iPS cell-rerived granulocyte transfusion strategyPrincipal Investigator

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Exploration of genes associated with efficacy of DNA methytransferase inhibitors for low risk MDS.

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Development of leukemia stem cell-specific therapy based on establishment of induced pluripotent stem cells derived from acute myeloid leukemia.Principal Investigator

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[Book] mRNAの制御機構の解明と治療薬・ワクチンへの活用2023

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[Book] RNA Therapeutics for Cancers2022

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YOSHIMI AKIHIDE 吉見昭秀

YOSHIMI Akihide 吉見昭秀