Furusawa Yukihiro 古澤之裕

… Alternative Names

FURUSAWA Yukihiro 古澤之裕

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Researcher Number	80632306
Other IDs
Affiliation (Current)	2025: 富山県立大学, 工学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 富山県立大学, 工学部, 准教授 2015 – 2019: 富山県立大学, 工学部, 講師 2014: 慶應義塾大学, 薬学部, 助教 2012 – 2013: 東京大学, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 38050:Food sciences-related / Basic Section 49070:Immunology-related / Gastroenterology / Immunology Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 90110:Biomedical engineering-related / Basic Section 52040:Radiological sciences-related / Basic Section 90150:Medical assistive technology-related / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Biomedical engineering/Biomaterial science and engineering / Immunology
Keywords	Principal Investigator 制御性T細胞 / 炎症性腸疾患 / エピジェネティクス / Treg / HDAC / 短鎖脂肪酸 / Transcription factor / Lysine acetyaltion / Butyrate / 腸管免疫 … More / 難消化性多糖類 / 大腸炎 / 腸内細菌 / 食物繊維 / PD-L1 / がん免疫 / IBD / 炎症生腸疾患 / DNAメチル化 … More Except Principal Investigator 超音波 / ゼブラフィッシュ / ピエゾ1 / メカノセンシング / 胆汁酸 / 腸内細菌 / タウリン / 炎症性サイトカイン / マクロファージ / 脂肪性肝炎 / 透過性 / 腸管上皮細胞 / アポトーシス / 大気圧プラズマ / ナノ粒子 / アクティブターゲティング / ナノメディシン / 細胞死 / 放射線 / 金ナノ粒子 / 光制御 / 深部体温 / 静脈血酸素飽和度 / 血中酸素飽和度 / ウェアラブルセンサ / 遺伝子改変個体 / 実験モデル動物 / 光 / 生体信号 / 細胞時計 / 体内時計 / miRNA / 熱作用 / 遺伝子発現 / 石灰化 / マイクロRNA / アクチン / 細胞分化 / カップリング因子 / 骨折モデル / 骨代謝 / ウロコ / 比較生理学 / トランスクリプトーム解析 / 細胞外小胞 / 破骨細胞分化 / 蛍光タンパク / 遺伝子組み換えゼブラフィッシュ / 骨修復過程 / 遺伝子応答 / パイエル板 / Ｍ細胞 / 粘膜免疫学 / M細胞 / 粘膜免疫 Less

Role of butyrate-targeted HDAC isozyme in the regulation of intestinal inflammationPrincipal Investigator
- Principal Investigator
  
  古澤之裕
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Toyama Prefectural University
Mechanistic elucidation of the preventive effect of pig-derived bile acids on life-related diseases through the improvement of gut barrier impairment
- Principal Investigator
  
  渡辺志朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Toyama
Elucidation of the health-promoting effects of taurine mediated by gut microbiota
- Principal Investigator
  
  村上茂
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fukui Prefectural University
Ultrasound mechanosensing: elucidation of the role of piezo1 on its regulation of cellular function
- Principal Investigator
  
  田渕圭章
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  University of Toyama
Enhancement of radiation-induced cancer cell death using active targetting gold nanoparticles
- Principal Investigator
  
  Kondo Taakshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Toyama
Preventive effect of indigestible polysaccharide on of inflammatory bowel disease through the alteration of gut microenvironment.Principal Investigator
- Principal Investigator
  
  Furusawa Yukihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Toyama Prefectural University
Elucidation of the role of miRNA on the control of cellular function by ultrasound
- Principal Investigator
  
  Tabuchi Yoshiaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  University of Toyama
体内時計の評価系の開発と光応答の理解によるヒト体内時計を光で調節する系の基盤確立
- Principal Investigator
  
  平山順
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90150:Medical assistive technology-related
- Research Institution
  Komatsu University
Identification of novel coupling factors produced by osteoclasts and clarification of their secretory phase
- Principal Investigator
  
  北村敬一郎
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  Kanazawa University
Enhancement of the anticancer immune response by epigenetic modificationPrincipal Investigator
- Principal Investigator
  
  Furusawa Yukihiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Toyama Prefectural University
Control of cell differentiation and proliferation by ultrasound: elucidation of the role of epigenome
- Principal Investigator
  
  Tabuchi Yoshiaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  University of Toyama
Induction of regulatory T cells by histone modification for the treatment of inflammation bowel diseasePrincipal Investigator
- Principal Investigator
  
  Furusawa Yukihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Toyama Prefectural University
  Keio University
Host-microbe interaction mediated by intestinal M cells
- Principal Investigator
  
  Hase Koji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Keio University
  The University of Tokyo
Commensal microbiota maintains gut homeostasis through epigenetic modificationPrincipal Investigator
- Principal Investigator
  
  FURUSAWA Yukihiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Effect of Wheat-Derived Arabinoxylan on the Gut Microbiota Composition and Colonic Regulatory T Cells.2023
- Author(s)
  Chudan S., Ishibashi R., Nishikawa M., Tabuchi Y., Nagai Y., Ikushiro S., Furusawa Y (Corresponding author).
- Journal Title
  
  Molecules
  
  Volume: 28 Issue: 7 Pages: 3079-3079
- DOI
  10.3390/molecules28073079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05929
[Journal Article] daptation to the shallow sea floor environment of a species of marine worms, Oligobrachia mashikoi, generally inhabiting deep-sea water.2023
- Author(s)
  Shouzo Ogiso, Kazuki Watanabe, Yusuke Maruyama, Hiroshi Miyake, Kaito Hatano, Jun Hirayama, Atsuhiko Hattori, Yukina Watabe, Toshio Sekiguchi, Yoichiro Kitani, Yukihiro Furusawa, Yoshiaki Tabuchi, Hajime Matsubara, Mana Nakagiri, Kenji Toyota, Yuichi Sasayama, Nobuo Suzuki.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 6299-6299
- DOI
  10.1038/s41598-023-33309-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15163, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-23K16821, KAKENHI-PROJECT-22KJ2575, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-23K05844, KAKENHI-PROJECT-21K05725
[Journal Article] Effect of soluble oat fiber on intestinal microenvironment and TNBS-induced colitis.2023
- Author(s)
  Chudan S., Ishibashi R., Nishikawa M., Tabuchi Y., Nagai Y., Ikushiro S., Furusawa Y (Corresponding author).
- Journal Title
  
  Food Funct
  
  Volume: 14 Issue: 4 Pages: 2188-2199
- DOI
  10.1039/d2fo03396h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05929, KAKENHI-PROJECT-21H02143
[Journal Article] Kynurenine promotes Calcitonin secretion and reduces cortisol in the Japanese flounder Paralichthys olivaceus2023
- Author(s)
  Ikari T, Furusawa Y, Tabuchi Y, Maruyama Y, Hattori A, Kitani Y, Toyota K, Nagami A, Hirayama J, Watanabe K, Shigematsu A, Rafiuddin MA, Ogiso S, Fukushi K, Kuroda K, Hatano K, Sekiguchi T, Kawashima R, Srivastav AK, Nishiuchi T, Sakatoku A, Yoshida M, Matsubara H, Suzuki N
- Journal Title
  
  Sci. Rep.
  
  Volume: In press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04565
[Journal Article] Possible involvement of Calcitonin I and II in calcium metabolism of the female reproductive physiology of goldfish (Carassius auratus).2023
- Author(s)
  Kuroda K, Hatano K, Kawamura R, Fukushima A, Sasayama Y, Tabuchi Y, Furusawa Y, Ikegame M, Hattori A, Hirayama J, Fukuda T, Uekura S, Matsubara H, Kawago U, Sekiguchi T, Srivastav A.K, Suzuki N
- Journal Title
  
  Int. Aquat. Res.
  
  Volume: 15 Pages: 15-26
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04565
[Journal Article] Osteoclastic and Osteoblastic Responses to Hypergravity and Microgravity: Analysis Using Goldfish Scales as a Bone Model2022
- Author(s)
  Yamamoto Tatsuki、Ikegame Mika、Furusawa Yukihiro、Tabuchi Yoshiaki、Hatano Kaito、Watanabe Kazuki、Kawago Umi、Hirayama Jun、Yano Sachiko、Sekiguchi Toshio、Kitamura Kei-ichiro、Endo Masato、Nagami Arata、Matsubara Hajime、Maruyama Yusuke、Hattori Atsuhiko、Suzuki Nobuo
- Journal Title
  
  Zoological Science
  
  Volume: 39 Issue: 4 Pages: 388-396
- DOI
  10.2108/zs210107
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-21K05725, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-18K11016, KAKENHI-PROJECT-20K06718, KAKENHI-PROJECT-20K12619, KAKENHI-PROJECT-22KJ2575
[Journal Article] Analysis of the thermal responses in Japanese pearl oysters, Pinctada fucata martensii2022
- Author(s)
  Hatano K, Kawamura R, Watabe Y, Ogiso S, Nagami A, Matsubara H, Urata M, Matsumoto K, Yachiguchi K, Shimizu N, Hirayama J, Furusawa Y, Tabuchi Y, Srivastav AK, Suzuki N
- Journal Title
  
  Int. J. Zool. Inv.
  
  Volume: 8 Pages: 371-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04565
[Journal Article] Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin use and regulation as a countermeasure2022
- Author(s)
  Hirayama Jun、Hattori Atsuhiko、Takahashi Akihisa、Furusawa Yukihiro、Tabuchi Yoshiaki、Shibata Masahiro、Nagamatsu Aiko、Yano Sachiko、Maruyama Yusuke、Matsubara Hajime、Sekiguchi Toshio、Suzuki Nobuo
- Journal Title
  
  Journal of Pineal Research
  
  Volume: 74 Issue: 1
- DOI
  10.1111/jpi.12834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05725, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-18K11016
[Journal Article] Activation of RANKL-producing cells under simulated microgravity with a three-dimensional clinostat in regenerating goldfish scales2022
- Author(s)
  Yamamoto, T., Ikegame, M., Kuroda, K., Kobayashi-Sun, J., Hirayama, J., Kobayashi, I., Kawamura, R., Endo, M., Tabuchi, Y., Furusawa, Y., Yachiguchi, K., Sekiguchi, T., Matsubara, H., Yano, S., Hattori, A. and Suzuki, N.
- Journal Title
  
  Biological Sciences in Space
  
  Volume: 36 Issue: 0 Pages: 9-14
- DOI
  10.2187/bss.36.9
- ISSN
  0914-9201, 1349-967X
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06718, KAKENHI-PROJECT-20K12619
[Journal Article] Hydroxylated benzo[c]phenanthrene metabolites cause osteoblast apoptosis and skeletal abnormalities in fish2022
- Author(s)
  Suzuki Nobuo, Honda Masato, Sekiguchi Toshio, Toriba Akira, Tang Ning, Edward Nagato Go, Zhang Lulu, Hayakawa Kazuichi, et all.
- Journal Title
  
  Ecotoxicology and Environmental Safety
  
  Volume: 234 Pages: 113401-113401
- DOI
  10.1016/j.ecoenv.2022.113401
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20309, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-19K20435, KAKENHI-PROJECT-21K05725, KAKENHI-PROJECT-22K11823, KAKENHI-PROJECT-18K11016, KAKENHI-PROJECT-19K09794, KAKENHI-PROJECT-20K12619
[Journal Article] The Impact of Low‐Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha‐Cyclodextrin in Intestinal Inflammation2022
- Author(s)
  Yamanouchi Yuka、Chudan Seita、Ishibashi Riko、Ohue‐Kitano Ryuji、Nishikawa Miyu、Tabuchi Yoshiaki、Kimura Ikuo、Nagai Yoshinori、Ikushiro Shinichi、Furusawa Yukihiro
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 66 Issue: 22 Pages: 2200063-2200063
- DOI
  10.1002/mnfr.202200063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-20K05929, KAKENHI-PROJECT-20K11600
[Journal Article] Ultrasound-induced DNA damage and cellular response: Historical review, mechanisms analysis, and therapeutic implications2022
- Author(s)
  Furusaw Y, Kondo T, Tachibana K, Feril LB
- Journal Title
  
  Radiation Res
  
  Volume: 197 Issue: 6 Pages: 662-672
- DOI
  10.1667/rade-21-00140.1.s1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07668, KAKENHI-PROJECT-21K07697
[Journal Article] Low-intensity ultrasound inhibits melanoma cell proliferation in vitro and tumor growth in vivo2021
- Author(s)
  Feril Loreto B.、Yamaguchi Kazuki、Ikeda-Dantsuji Yurika、Furusawa Yukihiro、Tabuchi Yoshiaki、Takasaki Ichiro、Ogawa Ryohei、Cui Zheng-Guo、Tachibana Katsuro
- Journal Title
  
  Journal of Medical Ultrasonics
  
  Volume: 48 Issue: 4 Pages: 451-461
- DOI
  10.1007/s10396-021-01131-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10449, KAKENHI-PROJECT-20K12619
[Journal Article] Genetic response to low-intensity ultrasound on mouse ST2 bone marrow stromal cells2021
- Author(s)
  Tabuchi Yoshiaki、Hasegawa Hideyuki、Suzuki Nobuo、Furusawa Yukihiro、Hirano Tetsushi、Nagaoka Ryo、Hirayama Jun、Hoshi Nobuhiko、Mochizuki Takashi
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 23 Issue: 3 Pages: 173-173
- DOI
  10.3892/mmr.2020.11812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12619, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-18KT0068, KAKENHI-PROJECT-19H04277, KAKENHI-PROJECT-21K19846
[Journal Article] De novo transcriptome analysis and gene expression profiling of fish scales isolated from Carassius auratus during space flight: Impact of melatonin on gene expression in response to space radiation2020
- Author(s)
  Furusawa Yukihiro、Yamamoto Tatsuki、Hattori Atsuhiko、Suzuki Nobuo、Hirayama Jun、Sekiguchi Toshio、Tabuchi Yoshiaki
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 22 Pages: 2627-2636
- DOI
  10.3892/mmr.2020.11363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11016, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-18KT0068
[Journal Article] HIKESHI silencing can enhance mild hyperthermia sensitivity in human oral squamous cell carcinoma cells2020
- Author(s)
  YOSHIAKI TABUCHI, KEITA MAEKAWA, MISAKO TORIGOE, YUKIHIRO FURUSAWA, TETSUSHI HIRANO, SATSUKI MINAGAWA, TATSUYA YUNOKI, ATSUSHI HAYASHI
- Journal Title
  
  Int J Mol Med
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01353
[Journal Article] Expression of sclerostin in the regenerating scales of goldfish and its increase under microgravity during space flight2020
- Author(s)
  Yamamoto, T., Ikegame, M., Hirayama, J., Kitamura, K., Tabuchi, Y., Furusawa, Y., Sekiguchi, T., Endo, M., Mishima, H., Seki, A., Yano, S., Matsubara H., Hattori, A. and Suzuki, N.
- Journal Title
  
  Biomed. Res.
  
  Volume: 41 Issue: 6 Pages: 279-288
- DOI
  10.2220/biomedres.41.279
- NAID
  130007948844
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06718, KAKENHI-PROJECT-20K12619, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-18K05830, KAKENHI-PROJECT-18KT0068
[Journal Article] Low-intensity pulsed ultrasound promotes the expression of immediate-early genes in mouse ST2 bone marrow stromal cells2020
- Author(s)
  Tabuchi Y, Hasegawa H, Suzuki N, Furusawa Y, Hirano T, Nagaoka R, Takeuchi SI, Shiiba M, Mochizuki T
- Journal Title
  
  J Med Ultrason
  
  Volume: 47 Issue: 2 Pages: 193-201
- DOI
  10.1007/s10396-020-01007-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01353
[Journal Article] Detection of RANKL-producing cells and osteoclastic activation by the addition of exogenous RANKL in the regenerating scales of goldfish.2020
- Author(s)
  Yamamoto, T., Ikegame, M., Kawago, U., Tabuchi, Y., Hirayama, J., Sekiguchi, T., Furusawa, Y., Yachiguchi, K., Matsubara, H., Urata, M., Hattori, A. and Suzuki, N.
- Journal Title
  
  Biological Science in Space
  
  Volume: 34 Issue: 0 Pages: 34-40
- DOI
  10.2187/bss.34.34
- NAID
  130007884615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06718, KAKENHI-PROJECT-20K12619, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-18K05830, KAKENHI-PROJECT-18KT0068
[Journal Article] Melatonin is a potential drug for the prevention of bone loss during space flight2019
- Author(s)
  Ikegame Mika、7名、Sekiguchi Toshio、43名、Suzuki Nobuo
- Journal Title
  
  Journal of Pineal Research
  
  Volume: 67 Issue: 3 Pages: 1-13
- DOI
  10.1111/jpi.12594
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06312, KAKENHI-PROJECT-18K06432, KAKENHI-PROJECT-18K07668, KAKENHI-PROJECT-18K11016, KAKENHI-PROJECT-18KT0068, KAKENHI-PROJECT-16H04812, KAKENHI-PROJECT-17H03867, KAKENHI-PROJECT-18H02473, KAKENHI-PROJECT-20K20309, KAKENHI-PROJECT-16K11442, KAKENHI-PROJECT-18K06331
[Journal Article] Identification of genes and genetic networks associated with BAG3?dependent cell proliferation and cell survival in human cervical cancer HeLa cells2018
- Author(s)
  Furusawa Yukihiro、Yunoki Tatsuya、Hirano Tetsushi、Minagawa Satsuki、Izumi Hironori、Mori Hisashi、Hayashi Atsushi、Tabuchi Yoshiaki
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 18 Pages: 4138-4146
- DOI
  10.3892/mmr.2018.9383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01353, KAKENHI-PROJECT-17H06706
[Journal Article] Sequencing and Expression Analysis of Calcitonin Receptor in the Scales of Goldfish, Carassius auratus2018
- Author(s)
  Ikari Takahiro, Sekiguchi Toshio, Urata Makoto, Furusawa Yukihiro, Ikegame Mika, Kinoshita Yasuko, Kitamura Kei-ichiro, Nakabayashi Itsuko, Horita Motoshi, Tabuchi Yoshiaki, Hattori Atsuhiko, Srivastav Ajai K, Suzuki Nobuo
- Journal Title
  
  International Journal of Zoological Investigations
  
  Volume: 4 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01353
[Journal Article] 腸内細菌によるエピゲノム修飾を介した腸管制御性T細胞の誘導機構2017
- Author(s)
  古澤之裕
- Journal Title
  
  腸内細菌学会誌
  
  Volume: 31 Pages: 15-22
- NAID
  130005306433
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26713026
[Journal Article] 腸内細菌由来代謝物による免疫エピゲノム制御2015
- Author(s)
  古澤之裕，尾畑佑樹,　長谷耕二
- Journal Title
  
  細胞 2015年2月号
  
  Volume: 2 Pages: 5-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713026
[Journal Article] Pitfalls in global normalization of ChIP-seq data; A possible solution strategy2014
- Author(s)
  Furusawa Y, et. al.
- Journal Title
  
  Genomics Data
  
  Volume: 2 Pages: 176-180
- DOI
  10.1016/j.gdata.2014.06.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26713026
[Journal Article] Epigenetic regulator Uhrf1 is critical for functional expansion of colonic regulatory T cells2014
- Author(s)
  Obata Y, Furusawa Y , Endo TA, Sharif J, Takahashi D, Atarashi K, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi T, Tajima S, Ohara O, Honda K, Hori S, Ohno H, Koseki H, Hase K
- Journal Title
  
  Nat. Immunol
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24890293
[Journal Article] The epigenetic regulator Uhrf1 facilitates proliferation and maturation of colonic regulatory T cells2014
- Author(s)
  Yuuki Obata*, Yukihiro Furusawa*, Takaho A. Endo, Jafar Sharif, Daisuke Takahashi, Koji Atarashi, Manabu Nakayama, Satoshi Onawa, Yumiko Fujimura, Masumi Takahashi, Tomokatsu Ikawa, Takeshi Otsubo, Yuki I. Kawamura, Taeko Dohi, Shoji Tajima, Osamu Ohara, Kenya Honda, Shohei Hori, Hiroshi Ohno, Haruhiko Koseki and Koji Hase. 【* : 筆頭筆者】
- Journal Title
  
  Nature Immunology
  
  Volume: 15 Issue: 6 Pages: 571-579
- DOI
  10.1038/ni.2886
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PLANNED-23114008, KAKENHI-PROJECT-23247030, KAKENHI-PROJECT-23249015, KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24890293, KAKENHI-PUBLICLY-25118732, KAKENHI-PUBLICLY-25118733, KAKENHI-PROJECT-25291025, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460965, KAKENHI-PUBLICLY-26116709, KAKENHI-PROJECT-26293229, KAKENHI-PROJECT-26670472
[Journal Article] Commensal microbiota regulates T cell fate decision in the gut2014
- Author(s)
  Yukihiro Furusawa, Yuuki Obata and Koji Hase.
- Journal Title
  
  Seminars in Immunopathology
  
  Volume: 37 Issue: 1 Pages: 017-025
- DOI
  10.1007/s00281-014-0455-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PROJECT-25293114, KAKENHI-PUBLICLY-26116709, KAKENHI-PROJECT-26713026
[Journal Article] Commensal microbe-derived butyrate induces colonic regulatory T cells2013
- Author(s)
  Yukihiro Furusawa, Yuuki Obata, Shinji Fukuda, Takaho A. Endo, Gaku Nakato, Daisuke Takahashi, Yumiko Nakanishi, Chikako Uetake, Keiko Kato, Tamotsu Kato, Masumi Takahashi, Noriko N. Fukuda, Shinnosuke Murakami, Eiji Miyauchi, Shingo Hino, Koji Atarashi, Satoshi Onawa, Yumiko Fujimura, Trevor Lockett, Julie M. Clarke, David L. Topping, Masaru Tomita, Shohei Hori, Osamu Ohara, Tatsuya Morita, Haruhiko Koseki, J un Kikuchi, Kenya Honda, Koji Hase and Hiroshi Ohno
- Journal Title
  
  Nature
  
  Volume: 506 Issue: 7480 Pages: 446-450
- DOI
  10.1038/nature12721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PROJECT-13J05482, KAKENHI-PROJECT-23780131, KAKENHI-PUBLICLY-24117524, KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24249029, KAKENHI-PROJECT-24380072, KAKENHI-PUBLICLY-25118733, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25513012, KAKENHI-PROJECT-25660101, KAKENHI-PROJECT-23390123
[Presentation] HikeshiノックアウトHSC-3ヒト口腔扁平上皮がん細胞の温熱感受性．2023
- Author(s)
  田渕圭章，柚木達也，古澤之裕，皆川沙月，平野哲史，林　篤志
- Organizer
  日本ハイパーサーミア学会第 40 回大会
- Data Source
  KAKENHI-PROJECT-23K11802
[Presentation] マウス骨由来細胞における骨形成分化に対する低出力パルス超音波の作用2023
- Author(s)
  田渕圭章，平野哲史，古澤之裕，長岡　亮，大村眞朗，鈴木信雄，長谷川英之
- Organizer
  日本超音波医学会令和5年度第4回超音波分子診断治療研究会
- Data Source
  KAKENHI-PROJECT-23K11802
[Presentation] 宇宙空間における新規メラトニン誘導体のウロコの骨代謝に対する作用と地上における骨疾患モデル動物を用いた解析2023
- Author(s)
  鈴木信雄，古澤之裕，田渕圭章，関あずさ，高垣裕子，染井正徳，江尻貞一，池亀美華，黒田康平，関口俊男，松原　創，高橋昭久，平山　順，服部淳彦．
- Organizer
  日本宇宙生物科学会第37回大会
- Data Source
  KAKENHI-PROJECT-23K11802
[Presentation] 大気圧プラズマ誘発細胞死の温熱による増強2023
- Author(s)
  近藤隆, 村谷珠輝, 古澤之裕, 斉藤淳一, 橋爪博司, 田中宏昌, 石川健司, 堀勝
- Organizer
  第40回日本ハイパーサーミア学会
- Data Source
  KAKENHI-PROJECT-21K07697
[Presentation] アルファシクロデキストリン摂取による腸内微小環境の変化と薬剤誘発性腸炎の抑制2022
- Author(s)
  古澤之裕
- Organizer
  第38回シクロデキストリンシンポジウム
- Data Source
  KAKENHI-PROJECT-20K05929
[Presentation] 腸内微小環境に影響を与える水溶性食物繊維の比較検討2022
- Author(s)
  古澤之裕
- Organizer
  第18回食品免疫学会学術大会
- Data Source
  KAKENHI-PROJECT-20K05929
[Presentation] 水溶性食物繊維による腸内環境変化と腸炎抑制効果の比較2022
- Author(s)
  古澤之裕, 山之内祐香,中段晴太,石橋璃子,西川美宇, 長井良憲, 生城真一
- Organizer
  第27回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20K05929
[Presentation] Commensal microbiota maintains gut homeostasis through its metabolic products and epigenetic modification2021
- Author(s)
  Furusawa Y.
- Organizer
  6th Toyama-Basel Joint Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05929
[Presentation] 低粘性水溶性食物繊維による腸内微小環境の変動と実験的腸炎の抑制.2021
- Author(s)
  古澤之裕
- Organizer
  第75回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-20K05929
[Presentation] メラトニンは宇宙空間で引きこされる骨吸収を抑制する治療薬になる可能性がある.2019
- Author(s)
  鈴木信雄,　池亀美華，田渕圭章，古澤之裕，北村敬一郎，関口俊男，山本樹、矢野幸子，平山　順，服部淳彦.
- Organizer
  2019宇宙生物科学会
- Data Source
  KAKENHI-PROJECT-18K06331
[Presentation] 腸内細菌によるエピゲノム修飾を介した腸管免疫恒常性維持機構の解明2016
- Author(s)
  古澤　之裕
- Organizer
  第20回腸内細菌学会
- Place of Presentation
  東京
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-26713026
[Presentation] 腸内細菌によるエピジェネティクス修飾を介した免疫調節2016
- Author(s)
  古澤　之裕
- Organizer
  第9回北陸バイオシンポジウム
- Place of Presentation
  石川
- Year and Date
  2016-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-26713026
[Presentation] 腸内細菌によるエピジェネティクス修飾と免疫調節2016
- Author(s)
  古澤　之裕
- Organizer
  第7回北陸ライフサイエンスクラスターシンポジウム
- Place of Presentation
  石川
- Invited
- Data Source
  KAKENHI-PROJECT-26713026
[Presentation] A commensal microbe-derived short-chain fatty acid epigenetically induces colonic regulatory T cells.2013
- Author(s)
  Yukihiro Furusawa, Yuuki Obata and Koji Hase
- Organizer
  The 12th Awaji International Forum on Infection & Immunity.
- Place of Presentation
  Awaji, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25293114
[Presentation] Commensal microbiota shapes the gut immune system through epigenetic modifications2013
- Author(s)
  Yukihiro Furusawa, Yuuki Obata, Jafar Sharif, Shohei Hori, Hiroshi Ohno, Haruhiko Koseki, Koji Hase
- Organizer
  International Congress of Mucosal Immunology (ICMI 2013)
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-24890293
[Presentation] Commensal microbiota shapes gut immune system through epigenetic modification2013
- Author(s)
  Furusawa Y, Obata Y, Sharif J, Hori S, Ohno H, Koseki H, Hase K
- Organizer
  International Congress of Mucosal Immunology
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-24890293
[Presentation] Commensal microbiota shapes the gut immune system through epigenetic modifications2012
- Author(s)
  古澤　之裕
- Organizer
  IEIIS2012
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24890293
[Presentation] 腸内細菌によるエピジェネティック修飾を介した制御性T細胞の誘導
- Author(s)
  古澤之裕，尾畑佑樹,　長谷耕二,　大野博司,　福田真嗣
- Organizer
  第66回日本細胞生物学会
- Place of Presentation
  奈良
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26713026
[Presentation] 腸内細菌による免疫バリア修飾作用の解明
- Author(s)
  古澤之裕，尾畑佑樹,　長谷耕二
- Organizer
  第135年会日本薬学会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26713026

1. Tabuchi Yoshiaki (20322109)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. 長谷川英之 (00344698)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. 鈴木信雄 (60242476)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. 平山順 (90510363)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
5. ENDO Takaho (40384862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Hase Koji (20359714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. MIMURO Hitomi (80396887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KIMURA Shunsuke (40444525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kondo Taakshi (40143937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 星信彦 (10209223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 池亀美華 (70282986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 北村敬一郎 (80283117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 小林功 (30774757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 野川雅道 (40292445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 三澤雅樹 (60358083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 齋藤淳一 (70572816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 趙慶利 (90313593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 延山知弘 (20900294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 渡邉康春 (80646307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 渡辺志朗 (00222406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 村上茂 (50740990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 宮崎照雄 (60532687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 伊藤崇志 (80423119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 松崎千秋 (90747924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. CUI Zheng-guo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. TOU Nei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. NAGAI Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 服部淳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
29. 豊田賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 松原創

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 鳥羽陽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 早川和一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 長門豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 関口俊男

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Furusawa Yukihiro 古澤 之裕

FURUSAWA Yukihiro 古澤 之裕

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Role of butyrate-targeted HDAC isozyme in the regulation of intestinal inflammationPrincipal Investigator

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Preventive effect of indigestible polysaccharide on of inflammatory bowel disease through the alteration of gut microenvironment.Principal Investigator

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Enhancement of the anticancer immune response by epigenetic modificationPrincipal Investigator

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Induction of regulatory T cells by histone modification for the treatment of inflammation bowel diseasePrincipal Investigator

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Commensal microbiota maintains gut homeostasis through epigenetic modificationPrincipal Investigator

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Furusawa Yukihiro 古澤之裕

FURUSAWA Yukihiro 古澤之裕