JINGUSHI KENTARO 神宮司健太郎

… Alternative Names

Jingushi Kentaro 神宮司健太郎

JINGUSHI Kentaro 神宮司健太郎

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Researcher Number	80707571
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院薬学研究科, 講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 大阪大学, 大学院薬学研究科, 特任講師(常勤) 2019 – 2021: 大阪大学, 薬学研究科, 特任講師(常勤) 2017: 大阪大学, 医学系研究科, 寄附講座助教 2016: 大阪大学, 大学院薬学研究科・分子細胞生理学, 招へい教員 2013 – 2014: 大阪大学, 薬学研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 47040:Pharmacology-related / Basic Section 56030:Urology-related / Pathological medical chemistry / Biological pharmacy Except Principal Investigator Basic Section 56030:Urology-related / Urology
Keywords	Principal Investigator 腎癌 / 腫瘍免疫 / EV抗体 / 癌組織放出細胞外小胞 / 抗癌EV抗体 / 大腸癌 / 癌組織EV / 癌EV / 癌EV抗体 / 細胞外小胞 … More / 癌 / 癌微小環境 / 癌抑制性miRNA / バイオマーカー / エクソソーム / 血清エクソソーム / TGF-β/Smadシグナル伝達経路 / EMT / ccRCC / TGF-bシグナル伝達経路 / miR-629 … More Except Principal Investigator 腎細胞癌 / 尿路上皮癌 / 細胞外小胞 / エクソソーム / 血液 / 細菌叢 / Ｄアミノ酸 / CD31 / 血管新生 / Cutibacterium acnes / 制御性T細胞 / Firmicutes / 癌免疫療法 / 細菌関連代謝物 / 血液内細菌叢 / 血液細菌叢 / 腫瘍微小環境 / 腫瘍免疫 / 腫瘍代謝 / Dアラニン / 早期血液診断薬 / Dアミノ酸 / 腎癌組織内免疫 / 血液内細菌情報 / 細菌遺伝情報 / 再発予測因子 / マイクロアレイ解析 / マイクロRNA / miRNA Less

血液細胞外小胞を基軸とした腸-腫瘍連関メカニズムの解明Principal Investigator
- Principal Investigator
  
  神宮司健太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Osaka
腎細胞癌局所内免疫状態を構築する血液内細菌叢の同定
- Principal Investigator
  
  植村俊彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
尿路上皮癌患者におけるD-アミノ酸発現意義の解明
- Principal Investigator
  
  山本顕生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
Elucidation of the cancer local immune status constructed by the systemic circulating microbiome and bacterial-related metabolism in urogenital cancer
- Principal Investigator
  
  河嶋厚成
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
Development of humanized anti-Te-EVs antibody for novel cancer therapyPrincipal Investigator
- Principal Investigator
  
  Jingushi Kentaro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka University
Identification and analysis of tumor suppressive miRNAs in RCCPrincipal Investigator
- Principal Investigator
  
  Jingushi Kentaro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
血清エクソソームバイオマーカーによる腎癌早期診断実現に向けた研究Principal Investigator
- Principal Investigator
  
  神宮司健太郎
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Development of a novel method to analyze cancer-derived circulating exosomes
- Principal Investigator
  
  Uemura Motohide
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Osaka University
Analysis of highly expressed miR-629 in clear cell renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  JINGUSHI Kentaro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2019 2017 2015 2014 Other

All Journal Article Presentation Patent

[Journal Article] Cutibacterium acnes‐derived extracellular vesicles promote tumor growth in renal cell carcinoma2024
- Author(s)
  Jingushi Kentaro、Kawashima Atsunari、Tanikawa Sayaka、Saito Takuro、Yamamoto Akinaru、Uemura Toshihiro、Sassi Nesrine、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Hase Hiroaki、Nonomura Norio、Tsujikawa Kazutake
- Journal Title
  
  Cancer Science
  
  Volume: 1 Issue: 8 Pages: 1-1
- DOI
  10.1111/cas.16202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24472
[Journal Article] Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma2023
- Author(s)
  Uemura Toshihiro、Kawashima Atsunari、Jingushi Kentaro、Motooka Daisuke、Saito Takuro、Nesrine Sassi、Oka Toshiki、Okuda Yohei、Yamamoto Akinaru、Yamamichi Gaku、Tomiyama Eisuke、Ishizuya Yu、Yamamoto Yoshiyuki、Kato Taigo、Hatano Koji、Tsujikawa Kazutake、Wada Hisashi、Nonomura Norio
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 9 Pages: e19800-e19800
- DOI
  10.1016/j.heliyon.2023.e19800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09469, KAKENHI-PROJECT-23K24472
[Journal Article] Circulating extracellular vesicles carrying Firmicutes reflective of the local immune status may predict clinical response to pembrolizumab in urothelial carcinoma patients2022
- Author(s)
  Jingushi Kentaro,Kawashima Atsunari、Saito Takuro、Kanazawa Takayuki、Motooka Daisuke、Kimura Tomonori、Mita Masashi、Yamamoto Akinaru、Uemura Toshihiro、Yamamichi Gaku、Okada Koichi、Tomiyama Eisuke、Koh Yoko、Matsushita Makoto、Kato Taigo、Hatano Koji、Uemura Motohide、Tsujikawa Kazutake、Wada Hisashi、Nonomura Norio
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 71 Issue: 12 Pages: 2999-3011
- DOI
  10.1007/s00262-022-03213-5
- Data Source
  KAKENHI-PROJECT-21K20968, KAKENHI-PROJECT-23K24472
[Journal Article] Extracellular vesicles isolated from human renal cell carcinoma tissues disrupt vascular endothelial cell morphology via azurocidin2017
- Author(s)
  Jingushi Kentaro、Uemura Motohide、Ohnishi Naomi、Nakata Wataru、Fujita Kazutoshi、Naito Takuya、Fujii Risa、Saichi Naomi、Nonomura Norio、Tsujikawa Kazutake、Ueda Koji
- Journal Title
  
  International Journal of Cancer
  
  Volume: 142 Issue: 3 Pages: 607-617
- DOI
  10.1002/ijc.31080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-17K14999, KAKENHI-PROJECT-26710007, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17K17848
[Journal Article] miR-629 Targets TRIM33 to Promote TGFb/Smad Signaling and Metastatic Phenotypes in ccRCC2015
- Author(s)
  Kentaro Jingushi, Yuko Ueda, Kaori Kitae, Hiroaki Hase, Hiroshi Egawa, Ikumi Ohshio, Ryoji Kawakami, Yuri Kashiwagi, Yohei Tsukada, Takumi Kobayashi, Wataru Nakata, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura, and Kazutake Tsujikawa
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 13 Issue: 3 Pages: 565-574
- DOI
  10.1158/1541-7786.mcr-14-0300
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25893113
[Patent] がん検査方法及びがん治療剤2023
- Inventor(s)
  辻川和丈、神宮司健太郎
- Industrial Property Rights Holder
  辻川和丈、神宮司健太郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-107773
- Filing Date
  2023
- Acquisition Date
  2023
- Data Source
  KAKENHI-PROJECT-21K06575
[Presentation] Colorectal cancer-derived Te-EVs function as tumor promoter by targeting monocytes via EVs-tRNA2022
- Author(s)
  Yuya Monoe, Kentaro Jingushi, Yoshiaki Takano, Kohei Taniguchi, Kazumasa Komura, Kazutake Tsujikawa
- Organizer
  ISEV2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06575
[Presentation] Colorectal cancer derived Te-EVs function as tumor promoter by targeting monocytes via EVs-RNA2021
- Author(s)
  Yuya Monoe, Kentaro Jingushi, Yoshiaki Takano, Kohei Taniguchi, Komura Kazumasa, Hiroaki Hase, Kazutake Tsujikawa
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06575
[Presentation] 大腸癌放出細胞外小胞に内包されるsmall ＲＮＡ　は単球におけるＴｏｌｌ－ｌｉｋｅ　Ｒｅｃｅｐｔｏｒ　８を介して腫瘍促進的に働く2021
- Author(s)
  物江祐弥, 神宮司健太郎, 内藤拓也, 高野義章, 谷口高平, 小村和正, 長谷拓明, 辻川和丈
- Organizer
  第8回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06575
[Presentation] 腎癌予後不良性遺伝子群を包括的に標的とする癌抑制性miRNAの探索と評価2019
- Author(s)
  服部功、神宮司健太郎、長谷拓明、北惠郁緒里、上田裕子、植村元秀、野々村祝夫、辻川和丈
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K18583
[Presentation] Glycosylation promotes azurocidin sorting into EVs in clear cell renal cell carcinoma cells.2017
- Author(s)
  Jingushi K, Naito T, Uemura M, Ueda K, Fujita K, Nonomura N, Tsujikawa K
- Organizer
  ISEV 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17848
[Presentation] 糖鎖修飾はａｚｕｒｏｃｉｄｉｎのＥＶへの搭載に重要である2017
- Author(s)
  神宮司健太郎、植村元秀、植田幸嗣、藤田和利、河嶋厚成、氏家剛、辻川和丈、野々村祝夫
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K17848
[Presentation] MiR-629 targets TRIM33 to promote TGF-β/Smad signaling in clear cell renal cell carcinoma2014
- Author(s)
  Kentaro Jingushi, Wataru Nakata, Yuko Ueda, Kaori Kitae, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura, Kazutake Tsujikawa
- Organizer
  American Association for Cancer Research Annual Meeting 2014
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-25893113
[Presentation] 淡明細胞型腎細胞癌においてmiR-629はTRIM33を介してTGF-b/Smadシグナルを促進する
- Author(s)
  神宮司健太郎、江川博、中田渡、藤田和利、植村元秀、野々村祝夫、辻川和丈
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (横浜)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25893113
[Presentation] MiR-629 targets TRIM33 to promote TGF-b/Smad signaling in clear cell renal cell carcinoma
- Author(s)
  Kentaro Jingushi, Wataru Nakata, Yuko Ueda, Kaori Kitae, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura, Kazutake Tsujikawa
- Organizer
  AACR annual meeting 2014
- Place of Presentation
  San Diego Convention Center (San Diego)
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25893113

1. NONOMURA Norio (30263263)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. 河嶋厚成 (50746568)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. Uemura Motohide (40631015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. TSUJIKAWA Kazutake (10207376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 藤田和利 (50636181)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 木村友則 (00631300)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 植村俊彦 (60905941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 山本顕生 (50909653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 元岡大祐 (10636830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 西塔拓郎 (20646468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 和田尚 (70243459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UEDA Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

JINGUSHI KENTARO 神宮司 健太郎

Jingushi Kentaro 神宮司 健太郎

JINGUSHI Kentaro 神宮司 健太郎

Research Projects

Research Products

Co-Researchers

血液細胞外小胞を基軸とした腸-腫瘍連関メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腎細胞癌局所内免疫状態を構築する血液内細菌叢の同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

尿路上皮癌患者におけるD-アミノ酸発現意義の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the cancer local immune status constructed by the systemic circulating microbiome and bacterial-related metabolism in urogenital cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of humanized anti-Te-EVs antibody for novel cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and analysis of tumor suppressive miRNAs in RCCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

血清エクソソームバイオマーカーによる腎癌早期診断実現に向けた研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel method to analyze cancer-derived circulating exosomes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of highly expressed miR-629 in clear cell renal cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cutibacterium acnes‐derived extracellular vesicles promote tumor growth in renal cell carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circulating extracellular vesicles carrying Firmicutes reflective of the local immune status may predict clinical response to pembrolizumab in urothelial carcinoma patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracellular vesicles isolated from human renal cell carcinoma tissues disrupt vascular endothelial cell morphology via azurocidin2017

Author(s)

Journal Title

DOI

Data Source

JINGUSHI KENTARO 神宮司健太郎

Jingushi Kentaro 神宮司健太郎

JINGUSHI Kentaro 神宮司健太郎

[Presentation] 大腸癌放出細胞外小胞に内包されるsmall ＲＮＡ　は単球におけるＴｏｌｌ－ｌｉｋｅ　Ｒｅｃｅｐｔｏｒ　８を介して腫瘍促進的に働く2021

[Presentation] 腎癌予後不良性遺伝子群を包括的に標的とする癌抑制性miRNAの探索と評価2019