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Saio Tomohide  齋尾 智英

… Alternative Names

Tomohide Saio  齋尾 智英

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Researcher Number 80740802
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-3639-7399
Affiliation (Current) 2025: 徳島大学, 先端酵素学研究所, 教授
Affiliation (based on the past Project Information) *help 2020 – 2025: 徳島大学, 先端酵素学研究所, 教授
2016 – 2020: 北海道大学, 理学研究院, 助教
2015: 北海道大学, 理学(系)研究科(研究院), 助教
2015: 北海道大学, 大学院理学研究院, 助教
Review Section/Research Field
Principal Investigator
Complex systems / Basic Section 43020:Structural biochemistry-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Transformative Research Areas, Section (II) / Biological Sciences / Molecular biology
Except Principal Investigator
Bio-related chemistry / Basic Section 34020:Analytical chemistry-related / Broad Section F / Medium-sized Section 38:Agricultural chemistry and related fields / Transformative Research Areas, Section (II) / Basic Section 43020:Structural biochemistry-related / Broad Section B
Keywords
Principal Investigator
NMR / シャペロン / 立体構造 / タンパク質フォールディング / ダイナミクス / 結合キネティクス / 構造変化 / マルチドメインタンパク質 / ランタニドイオン / 高速AFM … More / フォールディング / 過渡的相互作用 / 複合体立体構造 / 立体構造解析 / 常磁性ランタニド / 多量体 / 相互作用解析 / 相分離シャペロン / 天然変性タンパク質 / LCタンパク質 / 液-液相分離 / 過渡的構造 / 中性子散乱 / 光技術 / 蛋白質フォールディング / キネティクス / 遅延制御 / 過渡構造 / ランタノイド / SAXS / ESR / 常磁性ランタノイドイオン / 活性制御 / 細胞壁合成 / 核磁気共鳴法 / 常磁性 / MurD / 常磁性タグ / フォールディング中間体 / 小胞体 / トリガーファクター / 二量体 / 速度論 / プロリン異性化 / 結合解離速度 / 分子シャペロン / 常磁性金属 / シャペロン複合体 / 溶液構造 / 電子伝達 / 呼吸鎖 … More
Except Principal Investigator
タンパク質 / 液-液相分離 / 構造揺らぎ / ナノディスク / シトクロムc / シトクロムc酸化酵素 / 神経変性疾患 / 蛍光プローブ / パターン認識 / 相互作用 / 天然ゴム / フラボノイド / フラボノイドメタボロン / 天然ゴム生合成マシナリ / 植物代謝マシナリ / タンパク質間相互作用 / メタボロン / 植物特化代謝 / ミスフォールディング / フォールディング / 超分子化学 / 遅延制御 / cross-β polymer / 低複雑性配列 / LLPS / アミロイド線維 / 中間径フィラメント / 天然変性タンパク質 / 相分離生物学 / 相分離破綻 / 相分離制御 / 相分離駆動 / 相分離シャペロン / アミロイド様線維 / 生物学的相分離 / cross-βポリマー / LCドメイン / 蛋白質ダイナミクス / 租視化分子動力学計算 / 中性子準弾性散乱 / MD連携解析 / 蛋白質階層間連携ダイナミクス / 蛋白質重水素化 / 階層関連ダイナミクス / 分子動力学計算 / ドメイン選択重水素化 / 新世代中性子構造生物学 / 計算機連携解析 / ドメインライゲーション / タンパク質重水素化 / 中性子溶液散乱 / 階層間連携ダイナミクス / 分子動力学シミュレーション / 重水素化 / 生体高分子ダイナミクス / 中性子散乱 / 電子伝達複合体 / 構造的揺らぎ / 脱水和 / 電子伝達経路 / TCS / 電子伝達 / ミトコンドリア呼吸鎖 / 電子伝達系 / シトクロム酸化酵素 / 生体膜モデル / ドッキングシミュレーション / MSP / ヘム / 電子伝達反応 Less
  • Research Projects

    (19 results)
  • Research Products

    (94 results)
  • Co-Researchers

    (36 People)
  •  化学・計測・数理の融合によるタンパク質フォールディングの過渡構造解析Principal Investigator

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      The University of Tokushima
  •  植物特化代謝における超分子的代謝マシナリの形成:多元構造解析による統合的理解

    • Principal Investigator
      中山 亨
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      Tohoku University
  •  Molecular dissection of plant specialized metabolism machineries

    • Principal Investigator
      中山 亨
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section F
    • Research Institution
      Tohoku University
  •  Stratification of Protein Aggregation States based on Pattern Recognition for Screening Factors Controlling Phase Separation

    • Principal Investigator
      冨田 峻介
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 34020:Analytical chemistry-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  光技術と構造生物学の融合による過渡構造解析Principal Investigator

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokushima
  •  Mechanism of chaperone activity modulation through promiscuous recognitionsPrincipal Investigator

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      The University of Tokushima
  •  Unraveling the mechanism of kinetic regulation in biomolecular foldingPrincipal Investigator

    • Principal Investigator
      SAIO Tomohide
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      The University of Tokushima
  •  Organization of kinetics-driven supramolecular chemistry

    • Principal Investigator
      Muraoka Takahiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Structural basis for recognition and regulation of protein folding intermediate by molecular chaperones in the endoplasmic reticulumPrincipal Investigator

    • Principal Investigator
      SAIO Tomohide
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokushima
  •  Regulatory mechanism of biological phase separation

    • Principal Investigator
      Mori Eiichiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Nara Medical University
  •  Structural basis for chaperone network mediated by semi-specific recognitionsPrincipal Investigator

    • Principal Investigator
      SAIO Tomohide
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      The University of Tokushima
      Hokkaido University
  •  相分離を介したシグナル伝達制御の構造基盤Principal Investigator

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Hokkaido University
  •  Neutron Structural Biology for New Generation

    • Principal Investigator
      Sugiyama Masaaki
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section B
    • Research Institution
      Kyoto University
  •  分子シャペロンの基質選択と活性発現における動的構造基盤Principal Investigator

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  NMRを主体としたタンパク質構造推移解析のための複合手法の開発と応用Principal Investigator

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Hokkaido University
  •  Dynamic Structural Characterization of Electron Transfer Complex in Respiratory Chain of Mitochondria and Its Electron Transfer Regulation Mechanism

    • Principal Investigator
      Ishimori koichiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bio-related chemistry
    • Research Institution
      Hokkaido University
  •  Analysis of respiratory electron transport chain using the paramagnetic probesPrincipal Investigator

    • Principal Investigator
      SAIO Tomohide
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Hokkaido University
  •  NMRを主体としたタンパク質構造推移解析のための複合手法の開発と応用Principal Investigator

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Hokkaido University
  •  Functional and Structural Characterization of Electron Transfer Reactions in Mitochondria Respiratory Chain Utilizing Nanodisc

    • Principal Investigator
      Ishimori Koichiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bio-related chemistry
    • Research Institution
      Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book Patent

  • [Book] Experimental Approaches of NMR Spectroscopy: Methodology and Application to Life Science and Materials Science, Chapter 8 Structural study of proteins by paramagnetic lanthanide probe methods2017

    • Author(s)
      Tomohide Saio and Fuyuhiko Inagaki
    • Total Pages
      636
    • Publisher
      Springer
    • ISBN
      9789811059667
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Book] Advanced Methods in Structural Biology, Chapter 17, NMR Structural Biology Using Paramagnetic Lanthanide Probe.2016

    • Author(s)
      Tomohide Saio, Fuyuhiko Inagaki.
    • Total Pages
      340
    • Publisher
      Tokyo: Springer Japan
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Book] Advanced Methods in Structural Biology, Chapter 20, NMR Structural Biology using Paramagnetic Lanthanide Probe2016

    • Author(s)
      Tomohide Saio, Fuyuhiko Inagaki
    • Publisher
      Springer
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Journal Article] Enzymatic and synthetic regulation of polypeptide folding2024

    • Author(s)
      Muraoka Takahiro、Okumura Masaki、Saio Tomohide
    • Journal Title

      Chemical Science

      Volume: 15 Issue: 7 Pages: 2282-2299

    • DOI

      10.1039/d3sc05781j

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23KK0105, KAKENHI-ORGANIZER-21H05093, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-23K23472
  • [Journal Article] Heat-Induced Conformational Transition Mechanism of Heat Shock Factor 1 Investigated by Tryptophan Probe2022

    • Author(s)
      Kawagoe Soichiro、Kumashiro Munehiro、Mabuchi Takuya、Kumeta Hiroyuki、Ishimori Koichiro、Saio Tomohide
    • Journal Title

      Biochemistry

      Volume: 61 Issue: 24 Pages: 2897-2908

    • DOI

      10.1021/acs.biochem.2c00492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H05229, KAKENHI-PLANNED-19H05769
  • [Journal Article] Structural and Kinetic Views of Molecular Chaperones in Multidomain Protein Folding2022

    • Author(s)
      Kawagoe Soichiro、Ishimori Koichiro、Saio Tomohide
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 5 Pages: 2485-2485

    • DOI

      10.3390/ijms23052485

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20J20761
  • [Journal Article] Biophysical elucidation of neural network and chemical regeneration of neural tissue2022

    • Author(s)
      Takahiro Muraoka, Tomohide Saio, Masaki Okumura
    • Journal Title

      Biophysics and Physicobiology

      Volume: 19 Issue: 0 Pages: n/a

    • DOI

      10.2142/biophysico.bppb-v19.0024

    • ISSN
      2189-4779
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21H05093, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-23K23472
  • [Journal Article] Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells2022

    • Author(s)
      Miyake Masato、Sobajima Mitsuaki、Kurahashi Kiyoe、Shigenaga Akira、Denda Masaya、Otaka Akira、Saio Tomohide、Sakane Naoki、Kosako Hidetaka、Oyadomari Seiichi
    • Journal Title

      Cell Chemical Biology

      Volume: 7 Issue: 6 Pages: 996-1009

    • DOI

      10.1016/j.chembiol.2022.01.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02853, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-22K15253, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20K08909
  • [Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021

    • Author(s)
      Okumura M, Kanemura S., Matsusaki M., Kinoshita M., Saio T., Ito D., Hirayama C., Kumeta H., Watabe M., Amagai Y., Lee Y. H., Akiyama S. and Inaba K.
    • Journal Title

      Structure

      Volume: 29 Issue: 12 Pages: 1-14

    • DOI

      10.1016/j.str.2021.03.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19J00893, KAKENHI-PROJECT-20J11932, KAKENHI-PROJECT-19K06520, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PUBLICLY-19H04945, KAKENHI-PLANNED-21H05253
  • [Journal Article] Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex2021

    • Author(s)
      Rizzolo Kamran、Yu Angela Yeou Hsiung、Ologbenla Adedeji、Kim Sa-Rang、Zhu Haojie、Ishimori Koichiro、Thibault Guillaume、Leung Elisa、Zhang Yi Wen、Teng Mona、Haniszewski Marta、Miah Noha、Phanse Sadhna、Minic Zoran、Lee Sukyeong、Caballero Julio Diaz、Babu Mohan、Tsai Francis T. F.、Saio Tomohide、Houry Walid A.
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 281-281

    • DOI

      10.1038/s41467-020-20553-x

    • NAID

      120007186802

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229, KAKENHI-PUBLICLY-19H04945
  • [Journal Article] Conformational dynamics of a multidomain protein by neutron scattering and computational analysis2021

    • Author(s)
      Nakagawa Hiroshi、Saio Tomohide、Nagao Michihiro、Inoue Rintaro、Sugiyama Masaaki、Ajito Satoshi、Tominaga Taiki、Kawakita Yukinobu
    • Journal Title

      Biophysical Journal

      Volume: 120 Issue: 16 Pages: 3341-3354

    • DOI

      10.1016/j.bpj.2021.07.001

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H02944, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-19KK0071
  • [Journal Article] C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers2021

    • Author(s)
      Nanaura Hitoki、Aiba Yuichiro、Nakanishi Mari、Shiota Tomo、Hibino Masaki、Kikuchi Sotaro、Nagata Riko、Morikawa Naritaka、Iguchi Naohiko、Kiriyama Takao、Nagamori Shushi、Sugie Kazuma、Saio Tomohide、Yoshizawa Takuya、Mori Eiichiro et al.
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 5301-5301

    • DOI

      10.1038/s41467-021-25560-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-19K16060, KAKENHI-PROJECT-20K16583, KAKENHI-PROJECT-18H03984, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-20K06493, KAKENHI-PROJECT-20K06527, KAKENHI-PROJECT-20K06569, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-21K15032, KAKENHI-PROJECT-19KK0071, KAKENHI-PROJECT-22KJ0024, KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-19H05648
  • [Journal Article] Deuteration Aiming for Neutron Scattering2021

    • Author(s)
      Okuda Aya、Inoue Rintaro、Morishima Ken、Saio Tomohide、Yunoki Yasuhiro、Yagi-Utsumi Maho、Yagi Hirokazu、Shimizu Masahiro、Sato Nobuhiro、Urade Reiko、Kato Koichi、Sugiyama Masaaki
    • Journal Title

      Biophysics and Physicobiology

      Volume: 18 Issue: 0 Pages: 16-27

    • DOI

      10.2142/biophysico.bppb-v18.003

    • NAID

      130008000165

    • ISSN
      2189-4779
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-20K22629, KAKENHI-PROJECT-19KK0071, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-18J21063, KAKENHI-PROJECT-19K16088
  • [Journal Article] Zinc-Dependent Oligomerization of Thermus thermophilus Trigger Factor Chaperone2021

    • Author(s)
      Zhu Haojie、Matsusaki Motonori、Sugawara Taiga、Ishimori Koichiro、Saio Tomohide
    • Journal Title

      Biology

      Volume: 10 Issue: 11 Pages: 1106-1106

    • DOI

      10.3390/biology10111106

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K15969, KAKENHI-PLANNED-19H05769, KAKENHI-PROJECT-18H05229
  • [Journal Article] Conformational ensemble of a multidomain protein explored by Gd3+ electron paramagnetic resonance2021

    • Author(s)
      Saio, T., Hiramatsu, S., Asada, M., Nakagawa, H., Shimizu, K., Kumeta, H., Nakamura, T., Ishimori, K.
    • Journal Title

      Biophys. J.

      Volume: 120 Issue: 15 Pages: 2943-2951

    • DOI

      10.1016/j.bpj.2021.06.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05769, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H02944
  • [Journal Article] Solution NMR for investigation of liquid-liquid phase separation2020

    • Author(s)
      Saio Tomohide、Okumura Masaki、Lee Young-Ho
    • Journal Title

      Journal of the Korean Magnetic Resonance Society

      Volume: 24 Pages: 47-52

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Journal Article] Biological phase separation: cell biology meets biophysics2020

    • Author(s)
      Takuya Yoshizawa、Ryu-Suke Nozawa、Tony Z. Jia、Tomohide Saio、Eiichiro Mori
    • Journal Title

      Biophysical Reviews

      Volume: 12 Issue: 2 Pages: 519-539

    • DOI

      10.1007/s12551-020-00680-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16060, KAKENHI-PROJECT-18K14354, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H03190, KAKENHI-PUBLICLY-19H04945
  • [Journal Article] Dynamics of proteins with different molecular structures under solution condition2020

    • Author(s)
      Inoue Rintaro、Oda Takashi、Nakagawa Hiroshi、Tominaga Taiki、Saio Tomohide、Kawakita Yukinobu、Shimizu Masahiro、Okuda Aya、Morishima Ken、Sato Nobuhiro、Urade Reiko、Sato Mamoru、Sugiyama Masaaki
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 21678-21678

    • DOI

      10.1038/s41598-020-78311-4

    • NAID

      120007193758

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06527, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-19KK0071, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-18H02391, KAKENHI-PROJECT-20H02944, KAKENHI-PROJECT-19K16088, KAKENHI-PUBLICLY-19H04945
  • [Journal Article] 検出技術:天然変性蛋白質の構造生物学2020

    • Author(s)
      小田 隆、齋尾智英
    • Journal Title

      生物工学

      Volume: 98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Journal Article] Distance Distribution between Two Iodine Atoms Derived from Small-Angle X-ray Scattering Interferometry for Analyzing a Conformational Ensemble of Heavy Atom-Labeled Small Molecules2020

    • Author(s)
      Taguchi Yuya、Saio Tomohide、Kohda Daisuke
    • Journal Title

      The Journal of Physical Chemistry Letters

      Volume: 11 Issue: 14 Pages: 5451-5456

    • DOI

      10.1021/acs.jpclett.0c01107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H05229, KAKENHI-PUBLICLY-19H04945
  • [Journal Article] Toxic PR poly-dipeptides encoded by the C9orf72 repeat expansion target Kapβ2 and dysregulate phase separation of low-complexity domains.2019

    • Author(s)
      Nanaura H, Kawamukai H, Fujiwara A, Uehara T, Nakanishi M, Shiota T, Hibino M, Aiba Y, Wiriyasermkul P, Kikuchi S, Nagata R, Matsubayashi M, Nagamori S, Shoji O, Ishimori K, Matsumura H, Sugie K, Saio T*, Yoshizawa T*, Mori E
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/812099

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K21306, KAKENHI-PUBLICLY-19H04945
  • [Journal Article] Accelerating structural life science by paramagnetic lanthanide probe methods2019

    • Author(s)
      Saio Tomohide、Ishimori Koichiro
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: - Issue: 2 Pages: 129332-129332

    • DOI

      10.1016/j.bbagen.2019.03.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05657, KAKENHI-PROJECT-18H05229, KAKENHI-PUBLICLY-17H05867, KAKENHI-PLANNED-19H05769, KAKENHI-PUBLICLY-19H04945
  • [Journal Article] Dynamic assembly of protein disulfide isomerase in catalysis of oxidative folding2019

    • Author(s)
      Okumura Masaki、Noi Kentaro、Kanemura Shingo、Kinoshita Misaki、Saio Tomohide、Inoue Yuichi、Hikima Takaaki、Akiyama Shuji、Ogura Teru、Inaba Kenji
    • Journal Title

      Nature Chemical Biology

      Volume: 15 Issue: 5 Pages: 499-509

    • DOI

      10.1038/s41589-019-0268-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05657, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-17H06521, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-18H03978, KAKENHI-PLANNED-26116005, KAKENHI-PUBLICLY-17H05867, KAKENHI-PUBLICLY-19H04945
  • [Journal Article] Polyethylene glycol promotes autoxidation of cytochrome c2018

    • Author(s)
      Sato Wataru、Uchida Takeshi、Saio Tomohide、Ishimori Koichiro
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1862 Issue: 6 Pages: 1339-1349

    • DOI

      10.1016/j.bbagen.2018.03.010

    • NAID

      120006585774

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04173, KAKENHI-PROJECT-17J01146
  • [Journal Article] Oligomerization of a molecular chaperone modulates its activity2018

    • Author(s)
      Saio Tomohide、Kawagoe Soichiro、Ishimori Koichiro、Kalodimos Charalampos G
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.35731

    • NAID

      120006581597

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05657, KAKENHI-PUBLICLY-17H05867
  • [Journal Article] Structural insight into proline cis/trans isomerization of unfolded proteins catalyzed by the trigger factor chaperone2018

    • Author(s)
      Kawagoe Soichiro、Nakagawa Hiroshi、Kumeta Hiroyuki、Ishimori Koichiro、Saio Tomohide
    • Journal Title

      Journal of Biological Chemistry

      Volume: 293 Issue: 39 Pages: 15095-15106

    • DOI

      10.1074/jbc.ra118.003579

    • NAID

      120006585777

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05657, KAKENHI-PROJECT-18H05229, KAKENHI-PUBLICLY-17H05867
  • [Journal Article] Investigation of the Redox-dependent Modulation of Structure and Dynamics in Human Cytochrome c2016

    • Author(s)
      Imai, M., Saio, T., Kumata, H., Uchida, T., Inagaki, F., Ishimori, K.
    • Journal Title

      Biochemical and Biophysical Research Communication

      Volume: 469 Pages: 978-984

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25288072
  • [Journal Article] Energetic Mechanism of Cytochrome c - Cytochrome c Oxidase Electron Transfer Complex Formation under Turnover Conditions Revealed by Mutational Effects and Docking Simulation2016

    • Author(s)
      W. Sato, S. Hitaoka, K. Inoue, M. Imai, T. Saio, T. Uchida, K. Shinzawa-Itoh, S. Yoshikawa, K. Yoshizawa, and K. Ishimori
    • Journal Title

      J. Biol. Chem.

      Volume: 291 Issue: 29 Pages: 15320-15331

    • DOI

      10.1074/jbc.m115.708065

    • NAID

      120006324913

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24109014, KAKENHI-PROJECT-26291033, KAKENHI-PROJECT-15K13710, KAKENHI-PROJECT-15K20829
  • [Journal Article] Investigation of the redox-dependent modulation of structure and dynamics in human cytochrome c.2016

    • Author(s)
      Imai M, Saio T, Kumeta H, Uchida T, Inagaki F, Ishimori K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 469 Issue: 4 Pages: 978-984

    • DOI

      10.1016/j.bbrc.2015.12.079

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20829
  • [Journal Article] Ligand-driven conformational changes of MurD visualized by paramagnetic NMR.2015

    • Author(s)
      Saio T, Ogura K, Kumeta H, Kobashigawa Y, Shimizu K, Yokochi M, Kodama K, Yamaguchi H, Tsujishita H, Inagaki F.
    • Journal Title

      Sci Rep.

      Volume: 5 Issue: 1 Pages: 16685-16685

    • DOI

      10.1038/srep16685

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01624, KAKENHI-PROJECT-15H05183
  • [Patent] 液滴及びその製造方法2020

    • Inventor(s)
      奥村正樹,松﨑元 紀,金村進吾,稲葉 謙次,齋尾智英
    • Industrial Property Rights Holder
      奥村正樹,松﨑元 紀,金村進吾,稲葉 謙次,齋尾智英
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-100517
    • Filing Date
      2020
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] “Conformational distribution of a multi-domain protein enzyme investigated by paramagnetic NMR and ESR2023

    • Author(s)
      T. Saio
    • Organizer
      3rd India-Japan NMR WORK SHOP
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Structural insight into regulation and dysregulation of protein assembly and folding2023

    • Author(s)
      T. Saio
    • Organizer
      The 1st IMEG Meeting of The Research Center for High Depth Omics, Kumamoto
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Structural and kinetic views of regulators for protein folding and assembly2022

    • Author(s)
      T. Saio
    • Organizer
      International Symposium on Unfolded Proteins, Protein folding, and Disease-causing Aggregation, Korea
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] 新規光応答性シャペロンの創製とそれを利用した液-液相分離の制御2022

    • Author(s)
      太田 帆香,川越 聡一郎,松崎 元紀,久米田 博之,石森 浩一郎,齋尾 智英
    • Organizer
      2021年度 生物物理学会 北海道支部-東北支部合同例会
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] タンパク質液滴の形成・制御・破綻の分子メカニズム2022

    • Author(s)
      齋尾 智英
    • Organizer
      日本化学会第102春季年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Mechanistic insight into chaperone-mediated protein homeostasis2021

    • Author(s)
      Tomohide Saio
    • Organizer
      The 16th International Symposium of the Institute Network for Biomedical Sciences & KEY FORUM 2021 International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Mechanistic insights into a molecular chaperone in protein folding and degradation2021

    • Author(s)
      Tomohide Saio
    • Organizer
      2021 virtual Cold Spring Harbor Asia Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] ALS-associated factor PRn inhibit the function of KapB22021

    • Author(s)
      Honoka Kawamukai, Koichiro Ishimori, Tomohide Saio
    • Organizer
      The 16th International Symposium of the Institute Network for Biomedical Sciences & KEY FORUM 2021 International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] NMR investigation of molecular chaperones manipulating protein folding2021

    • Author(s)
      Tomohide Saio
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Mechanistic insights into a molecular chaperone in protein folding and degradation2021

    • Author(s)
      Tomohide Saio
    • Organizer
      2021 virtual Cold Spring Harbor Asia Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Structural and kinetic insights into a molecular chaperone for protein folding, translocation, and degradation2021

    • Author(s)
      Tomohide Saio
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Large-scale conformational distribution of a multi-domain protein enzyme investigated by NMR and EPR2021

    • Author(s)
      Tomohide Saio
    • Organizer
      第59回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] 多量体形成を介したシャぺロンの機能制御2021

    • Author(s)
      齋尾 智英
    • Organizer
      第44回 日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] ストレス応答を制御する転写因子Heat shock factor1の酸化還元依存的な相転移2021

    • Author(s)
      川越聡一郎、松崎元紀、石森浩一郎、齋尾智英
    • Organizer
      第44回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] 常磁性金属と分子シャペロン2020

    • Author(s)
      齋尾 智英
    • Organizer
      2020年度日本分光学会NMR分光部会 集中講義
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] シャペロンから理解する細胞内タンパク質の動態制御メカニズム2020

    • Author(s)
      齋尾 智英
    • Organizer
      第93回日本生化学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] On and off between molecular chaperones and clients: Appropriate distance and timing for protein folding2020

    • Author(s)
      Tomohide Saio
    • Organizer
      21st Hokudai-RIES International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] シャペロンから理解する細胞内タンパク質の動態制御メカニズム2020

    • Author(s)
      齋尾 智英
    • Organizer
      第93回日本生化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Exploiting paramagnetic metal ions for protein structural study in solution2020

    • Author(s)
      齋尾 智英, 石森 浩一郎
    • Organizer
      第 58 回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] 常磁性金属と分子シャペロン2020

    • Author(s)
      齋尾 智英
    • Organizer
      2020年度日本分光学会NMR分光部会 集中講義
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Exploiting paramagnetic metal ions for protein structural study in solution2020

    • Author(s)
      齋尾 智英, 石森 浩一郎
    • Organizer
      第 58 回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] On and off between molecular chaperones and clients: Appropriate distance and timing for protein folding2020

    • Author(s)
      Tomohide Saio
    • Organizer
      21st Hokudai-RIES International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] 細胞内恒常性維持を担うシャペロンの動的構造基盤と制御2019

    • Author(s)
      齋尾 智英
    • Organizer
      日本生化学会北海道支部 第56 回支部例会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Applications of paramagnetic lanthanide ions in NMR and ESR2019

    • Author(s)
      Tomohide Saio
    • Organizer
      International IPR Seminar -Open up a new era of structural biology with advanced NMR study-
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Applications of paramagnetic lanthanide ions in NMR and ESR2019

    • Author(s)
      T. Saio
    • Organizer
      International IPR Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] 細胞内恒常性維持を担うシャペロンの動的構造基盤と制御2019

    • Author(s)
      齋尾 智英
    • Organizer
      日本化学会北海道支部 奨励賞受賞講演
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019

    • Author(s)
      T.Saio
    • Organizer
      8th Asia-Pacific NMR Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Protein structure and dynamics by solution NMR2019

    • Author(s)
      Tomohide Saio
    • Organizer
      ASUKA Symposium 2019
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] タンパク質フォールディングにおける分子シャペロンの機能とメカニズム: 立体構造と速度論からのアプローチ2019

    • Author(s)
      齋尾 智英
    • Organizer
      第92 回 日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] 金属イオンを用いたSAXSとNMRによるマルチドメインタンパク質の動的構造解析2019

    • Author(s)
      齋尾 智英
    • Organizer
      PF研究会 -BioSASが拓く生体高分子の分子間相互作用解析の最前線-
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] 金属イオンを用いたSAXSとNMRによるマルチドメイン蛋白質の動的構造解析2019

    • Author(s)
      齋尾智英
    • Organizer
      PF研究会「BioSASが拓く生体高分子の分子間相互作用解析の最前線」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Exploring conformational states of a protein enzyme using paramagnetic lanthanide ions2019

    • Author(s)
      T.Saio
    • Organizer
      Biometal Science 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] QENS of protein solutions measured by the TOF near Backscattering Spectrometer DNA2019

    • Author(s)
      H. Nakagawa, T. Saio, T. Oda, M. Sato, R. Inoue, M. Sugiyama, T. Tominaga, Y. Kawakita
    • Organizer
      J-PARC Symposium 2019
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Exploring conformational states of a protein enzyme using paramagnetic lanthanide ions2019

    • Author(s)
      Tomohide Saio
    • Organizer
      Biometal Science 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] 低複雑性タンパク質の液-液相分離の制御と破綻のメカニズム: NMRによる解析2019

    • Author(s)
      齋尾 智英
    • Organizer
      第 4 回 LLPS 研究会・ASUKA 若手交流会 2019
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019

    • Author(s)
      Tomohide Saio
    • Organizer
      8th Asia-Pacific NMR Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019

    • Author(s)
      Tomohide Saio, Soichiro Kawagoe, Charalampos G Kalodimos, Koichiro Ishimori
    • Organizer
      8TH Asia-Pacific NMR 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019

    • Author(s)
      Tomohide Saio, Soichiro Kawagoe, Charalampos G Kalodimos, Koichiro Ishimori
    • Organizer
      8TH Asia-Pacific NMR 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05657
  • [Presentation] Structure and dynamics of molecular chaperones in protein folding, holding, and degradation2019

    • Author(s)
      齋尾 智英
    • Organizer
      第2回 タンパク質可塑性についての研究会 -タンパク質と人工分子のダイナミクスと機能相関-
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] 低複雑性蛋白質の液-液相分離の制御と破綻のメカニズム: NMRによる解析2019

    • Author(s)
      齋尾智英
    • Organizer
      第4回LLPS研究会・ASUKA若手交流会2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Structural and kinetic insights into molecular chaperones2019

    • Author(s)
      T. Saio
    • Organizer
      International Symposium on Protein Folding and Misfolding-related Aggregation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05229
  • [Presentation] Structural and kinetic insights into molecular chaperones2019

    • Author(s)
      Tomohide Saio
    • Organizer
      International Symposium on Protein Folding and Misfolding-related Aggregation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04945
  • [Presentation] Diverse activities of molecular chaperones through non-selective binding2018

    • Author(s)
      Tomohide Saio, Charalampos Kalodimos, Koichiro Ishimori
    • Organizer
      日本生物物理学会第56回年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] Modulation of chaperone activity by oligomerization2018

    • Author(s)
      Tomohide Saio, Soichiro Kawagoe, Koichiro Ishimori, Charalampos G. Kalodimos
    • Organizer
      28th International Conference on Magnetic Resonance in Biological Systems (ICMRBS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] Diverse activities of molecular chaperones through non-selective binding2018

    • Author(s)
      Tomohide Saio, Charalampos Kalodimos, Koichiro Ishimori
    • Organizer
      日本生物物理学会第56回年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05657
  • [Presentation] パルスEPRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2018

    • Author(s)
      平松 蒼野,齋尾 智英,浅田 瑞枝,瀧下 俊平,中村 敏和,石森 浩一郎
    • Organizer
      第55回生化学会北海道支部例会
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] Structural and kinetic insights into chaperone activities of Trigger Factor.2018

    • Author(s)
      Tomohide Saio
    • Organizer
      International Symposium -Proteins: from the Cradle to the Grave-
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] パルスEPRとGd3+を用いたマルチドメイン蛋白質MurDの立体構造変化の解析2018

    • Author(s)
      平松 蒼野,齋尾 智英,浅田 瑞枝,瀧下 俊平,中村 敏和,石森 浩一郎
    • Organizer
      第57回電子スピンサイエンス学会年会(SEST2018)
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] Modulation of chaperone activity by oligomerization2018

    • Author(s)
      Tomohide Saio, Soichiro Kawagoe, Koichiro Ishimori, Charalampos G. Kalodimos
    • Organizer
      28th International Conference on Magnetic Resonance in Biological Systems (ICMRBS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05657
  • [Presentation] Structural and kinetic insights into chaperone activities of Trigger Factor.2018

    • Author(s)
      Tomohide Saio
    • Organizer
      International Symposium -Proteins: from the Cradle to the Grave-
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05657
  • [Presentation] Exploring conformational equilibria of a multi-domain protein MurD by paramagnetic lanthanide probe in NMR and EPR2017

    • Author(s)
      Tomohide Saio, Soya Hiramatsu, Mizue Asada, Shunpei Takishita, Toshikazu Nakamura, Koichiro Ishimori
    • Organizer
      第17回 日本蛋白質科学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] パルスESRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2017

    • Author(s)
      平松 蒼野,齋尾 智英,浅田 瑞枝,瀧下 俊平,稲垣 冬彦,中村 敏和,石森 浩一郎
    • Organizer
      第17回 日本蛋白質科学会年会
    • Place of Presentation
      仙台国際センター (宮城県・仙台市)
    • Year and Date
      2017-06-20
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Presentation] パルスESRとガドリニウムタグを用いたマルチドメイン蛋白質MurDの構造変化解析2017

    • Author(s)
      平松 蒼野,齋尾 智英,浅田 瑞枝,瀧下 俊平,稲垣 冬彦,中村 敏和,石森 浩一郎
    • Organizer
      化学系学協会北海道支部2017冬季研究発表会
    • Place of Presentation
      北海道大学 (北海道・札幌市)
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Presentation] パルスESRとガドリニウムタグを用いたマルチドメイン蛋白質MurDの構造変化解析2017

    • Author(s)
      平松 蒼野, 齋尾 智英, 浅田 瑞枝, 瀧下 俊平, 稲垣 冬彦, 中村 敏和, 石森 浩一郎
    • Organizer
      化学系学協会北海道支部2017冬季研究発表会
    • Place of Presentation
      北海道大学 (北海道・札幌市)
    • Data Source
      KAKENHI-PROJECT-15K20829
  • [Presentation] Exploring conformational equilibria of a multi-domain protein MurD by paramagnetic lanthanide probe in NMR and EPR2017

    • Author(s)
      Tomohide Saio, Soya Hiramatsu, Mizue Asada, Shunpei Takishita, Toshikazu Nakamura, Koichiro Ishimori
    • Organizer
      第17回 日本蛋白質科学会年会
    • Place of Presentation
      仙台国際センター (宮城県・仙台市)
    • Year and Date
      2017-06-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K20829
  • [Presentation] パルスESRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2017

    • Author(s)
      平松 蒼野,齋尾 智英,浅田 瑞枝,瀧下 俊平,中村 敏和,石森 浩一郎
    • Organizer
      第17回 日本蛋白質科学会年会
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] マルチドメインタンパク質における構造アンサンブルと各構造の存在比の解析2017

    • Author(s)
      瀧下俊平, 齋尾智英, 平松蒼野, 久米田博之, 清水和美, 石森浩一郎
    • Organizer
      第56回 NMR討論会
    • Data Source
      KAKENHI-PUBLICLY-17H05867
  • [Presentation] パルスESRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2017

    • Author(s)
      平松 蒼野, 齋尾 智英, 浅田 瑞枝, 瀧下 俊平, 稲垣 冬彦, 中村 敏和, 石森 浩一郎
    • Organizer
      第17回 日本蛋白質科学会年会
    • Place of Presentation
      仙台国際センター (宮城県・仙台市)
    • Year and Date
      2017-06-20
    • Data Source
      KAKENHI-PROJECT-15K20829
  • [Presentation] Exploring conformational equilibria of a multi-domain protein MurD by paramagnetic lanthanide probe in NMR and EPR2017

    • Author(s)
      Tomohide Saio, Soya Hiramatsu, Mizue Asada, Shunpei Takishita, Toshikazu Nakamura, Koichiro Ishimori
    • Organizer
      第17回 日本蛋白質科学会年会
    • Place of Presentation
      仙台国際センター (宮城県・仙台市)
    • Year and Date
      2017-06-20
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Presentation] Dynamic Structural Changes Of A Multi-Domain Protein Probed By Paramagnetic NMR2016

    • Author(s)
      Shumpei Takishita, Tomohide Saio, Hiroyuki Kumeta, Fuyuhiko Inagaki, Koichiro Ishimori
    • Organizer
      The XXVIIth International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      国立京都国際会館 (京都府・京都市)
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Presentation] マルチドメインタンパク質の動的構造変化の解析への常磁性ランタノイドプローブを 用いたNMR法の応用2016

    • Author(s)
      瀧下 俊平, 齋尾 智英, 久米田 博之, 稲垣 冬彦, 石森 浩一郎
    • Organizer
      日本生物物理学会北海道支部例会
    • Place of Presentation
      北海道大学 (北海道札幌市)
    • Year and Date
      2016-03-14
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Presentation] ランタノイドイオンを用いたマルチドメインタンパク質の動的解析2016

    • Author(s)
      瀧下 俊平,齋尾 智英,久米田 博之,稲垣 冬彦,石森 浩一郎
    • Organizer
      第16回 日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場 (福岡県・福岡市)
    • Year and Date
      2016-06-07
    • Data Source
      KAKENHI-PUBLICLY-15H01624
  • [Presentation] Visualizing conformational changes of MurD by paramagnetic lanthanide probe2016

    • Author(s)
      Tomohide Saio
    • Organizer
      The 5th International Symposium on Drug Discovery and Design by NMR
    • Place of Presentation
      理化学研究所横浜事業所 (神奈川県・横浜市)
    • Year and Date
      2016-08-29
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01624
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