Matsusaki Motonori 松崎元紀

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MATSUSAKI Motonori 松崎元紀

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Researcher Number	90817040
Other IDs
Affiliation (Current)	2025: 徳島大学, 先端酵素学研究所, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 徳島大学, 先端酵素学研究所, 助教 2020: 東北大学, 学際科学フロンティア研究所, 特別研究員(PD) 2019: 東北大学, 多元物質科学研究所, 特別研究員(PD)
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Complex systems / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 43020:Structural biochemistry-related
Keywords	Principal Investigator 小胞体ストレス応答 / IRE1 / ジスルフィド結合 / タンパク質品質管理 / 小胞体 / 小胞体ストレスセンサー / ミスフォールドタンパク質 / PDIファミリー / 情報熱力学 / インスリン … More Except Principal Investigator … More 蛋白質品質管理 / メゾスケール構造体 / 分泌経路 / セクレトーム解析 / NMR / 立体構造 / 結合キネティクス / タンパク質フォールディング / シャペロン Less

分泌経路におけるメゾスケール構造体プロファイリングの開拓
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Tohoku University
Multidimensional endoplasmic reticulum stress sensing by IRE1Principal Investigator
- Principal Investigator
  
  MATSUSAKI Motonori
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  The University of Tokushima
細胞内ストレス応答の情報熱力学的な理解Principal Investigator
- Principal Investigator
  
  松崎元紀
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokushima
Mechanism of chaperone activity modulation through promiscuous recognitions
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokushima
Molecular mechanism of disulfide-bonded active oligomerization by an endoplasmic stress sensor IRE1Principal Investigator
- Principal Investigator
  
  MATSUSAKI Motonori
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  The University of Tokushima
Molecular mechanism of ER stress response regulation by PDI family proteinsPrincipal Investigator
- Principal Investigator
  
  松崎元紀
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Tohoku University

All 2024 2023 2021 2020 2019

All Journal Article Presentation

[Journal Article] Client recognition differences between PDI and ERp46 to guide oxidative folding2024
- Author(s)
  Saio Tomohide、Ishii Kotone、Matsusaki Motonori、Kumeta Hiroyuki、Kanemura Shingo、Okumura Masaki
- Journal Title
  
  bioRxiv
  
  Volume: 2024.03.04 Pages: 583432-583432
- DOI
  10.1101/2024.03.04.583432
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0105, KAKENHI-PLANNED-21H05095
[Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021
- Author(s)
  Okumura M, Kanemura S., Matsusaki M., Kinoshita M., Saio T., Ito D., Hirayama C., Kumeta H., Watabe M., Amagai Y., Lee Y. H., Akiyama S. and Inaba K.
- Journal Title
  
  Structure
  
  Volume: 29 Issue: 12 Pages: 1-14
- DOI
  10.1016/j.str.2021.03.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19J00893, KAKENHI-PROJECT-20J11932, KAKENHI-PROJECT-19K06520, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PUBLICLY-19H04945, KAKENHI-PLANNED-21H05253
[Journal Article] Conjugate of Thiol and Guanidyl Units with Oligoethylene Glycol Linkage for Manipulation of Oxidative Protein Folding2021
- Author(s)
  Okada Shunsuke、Matsusaki Motonori、Okumura Masaki、Muraoka Takahiro
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 4 Pages: 879-879
- DOI
  10.3390/molecules26040879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-19J00893, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19H02828, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095
[Journal Article] Functional Interplay between P5 and PDI/ERp72 to Drive Protein Folding.2021
- Author(s)
  Matsusaki M, Okada R, Tanikawa Y, Kanemura S, Ito D, Lin Y, Watabe M, Yamaguchi H, Saio T, Lee YH, Inaba K, and *Okumura M.
- Journal Title
  
  Biology
  
  Volume: 10 Issue: 11 Pages: 1112-1112
- DOI
  10.3390/biology10111112
- NAID
  120007168792
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
[Journal Article] Zinc-Dependent Oligomerization of Thermus thermophilus Trigger Factor Chaperone2021
- Author(s)
  Zhu Haojie、Matsusaki Motonori、Sugawara Taiga、Ishimori Koichiro、Saio Tomohide
- Journal Title
  
  Biology
  
  Volume: 10 Issue: 11 Pages: 1106-1106
- DOI
  10.3390/biology10111106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15969, KAKENHI-PLANNED-19H05769, KAKENHI-PROJECT-18H05229
[Journal Article] Ca2+ Regulates ERp57-Calnexin Complex Formation.2021
- Author(s)
  Tanikawa Y,# Kanemura S,# Ito D, Lin Y, Matsusaki M, Kuroki K, Yamaguchi H, Maenaka K, Lee YH, Inaba K, and *Okumura M.
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 10 Pages: 2853-2853
- DOI
  10.3390/molecules26102853
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
[Journal Article] PDI Family Members as Guides for Client Folding and Assembly2020
- Author(s)
  Kanemura S., Matsusaki M., Inaba K. and Okumura M.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 24 Pages: 9351-9351
- DOI
  10.3390/ijms21249351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19J00893
[Journal Article] 小胞体内におけるMHCの品質管理2020
- Author(s)
  金村進吾 , 松崎元紀 , 前仲勝実 , 稲葉謙次 , 奥村正樹
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 74 Pages: 419-426
- Data Source
  KAKENHI-PROJECT-19J00893
[Journal Article] 小胞体におけるMHCの品質管理2020
- Author(s)
  金村進吾 , 松崎元紀 , 前仲勝実 , 稲葉謙次 , 奥村正樹
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 74 Pages: 419-426
- Data Source
  KAKENHI-PROJECT-20K15969
[Journal Article] Regulation of plant ER oxidoreductin 1 (ERO1) activity for efficient oxidative protein folding2019
- Author(s)
  Matsusaki Motonori、Okuda Aya、Matsuo Koichi、Gekko Kunihiko、Masuda Taro、Naruo Yurika、Hirose Akiho、Kono Keiichi、Tsuchi Yuichiro、Urade Reiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 49 Pages: 18820-18835
- DOI
  10.1074/jbc.ra119.010917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06587, KAKENHI-PROJECT-19J00893
[Journal Article] Protein Disulfide Isomerase family: from Proteostasis to Pathogenesis2019
- Author(s)
  Matsusaki M.#, Kanemura S.#, Kinoshita M.#, Lee Y.H., Inaba K.*, and Okumura M.* (#equal contribution *corresponding authors)
- Journal Title
  
  Biochim Biophys Acta-general subjects
  
  Volume: in press Issue: 2 Pages: 30080-30087
- DOI
  10.1016/j.bbagen.2019.04.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-17H06521, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-19J00893
[Presentation] 小胞体ストレスセンサーIRE1による活性酸素種の直接的感知と分子シャペロンによるその制御2024
- Author(s)
  松崎元紀、金村進吾、齋尾智英、稲葉謙次、奥村正樹
- Organizer
  日本農芸化学会2024度大会
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] Elucidating the enzymatic reductive unfolding mechanism of spike/envelope proteins to guide anti-virus activities2023
- Author(s)
  Shingo Kanemura, Rina Hashimoto, Motonori Matsusaki, Takuya Mabuchi, Mai Watabe, Tomohide Saio, Kazuo Takayama, Young-Ho Lee, Masaki Okumura
- Organizer
  第23回日本蛋白質科学会年会　★若手賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 多量体分析で解き明かす小胞体ストレスセンサーが細胞応答を量的に調節する仕組み2023
- Author(s)
  松崎元紀、奥村正樹
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 小胞体ストレスセンサーIRE1の多量体形成ポテンシャルとストレス感知2023
- Author(s)
  松崎元紀、横山武司、次田篤史、金村進吾、田尻道子、明石知子、野井健太郎、齋尾智英、稲葉謙次、奥村正樹
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 小胞体ストレスセンサーIRE1 によるストレス感知と越膜シグナル変換の分子機構2023
- Author(s)
  松崎元紀、横山武司、次田篤史、金村進吾、田尻道子、明石知子、野井健太郎、齋尾智英、稲葉謙次、奥村正樹
- Organizer
  第96回日本生化学会
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 分子間ジスルフィド結合による小胞体ストレスセンサーIRE1の会合状態制御2021
- Author(s)
  松崎元紀, 横山武司, 次田篤史, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
- Organizer
  第6回東北大学若手研究者アンサンブルワークショップ
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] 分子間ジスルフィド結合による小胞体ストレスセンサーIRE1の会合状態制御2021
- Author(s)
  松崎元紀, 横山武司, 次田篤史, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
- Organizer
  第6回東北大学若手研究者アンサンブルワークショップ
- Data Source
  KAKENHI-PROJECT-20K15969
[Presentation] ミスフォールドタンパク質およびジスルフィド結合依存的なIRE1の会合状態制御2021
- Author(s)
  松崎元紀, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-20K15969
[Presentation] ミスフォールドタンパク質およびジスルフィド結合依存的なIRE1の会合状態制御2021
- Author(s)
  松崎元紀, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] Novel Insight into PDI Family-regulated IRE1 Activation/Inactivation2020
- Author(s)
  Motonori Matsusaki, Shingo Kanemura, Kenji Inaba, Masaki Okumura
- Organizer
  第20回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] Novel Insight into PDI Family-regulated IRE1 Activation/Inactivation2020
- Author(s)
  Motonori Matsusaki, Shingo Kanemura, Kenji Inaba, Masaki Okumura
- Organizer
  第20回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20K15969
[Presentation] PDI family酵素によるヒト由来ガレクチンの機能制御機構の解明2019
- Author(s)
  金村進吾、黒井邦巧、松崎元紀、山口宏、中林孝和、稲葉謙次、奥村正樹
- Organizer
  第92回日本生化学大会
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] 新規レドックス分子による酸化的フォールディングの促進と応用2019
- Author(s)
  松崎元紀、岡田隼輔、荒井堅太、日高雄二、稲葉謙次、村岡貴博、奥村正樹
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] Newly developed thiol-disulfide exchange agent, guanidino-thiol2019
- Author(s)
  M. Matsusaki, S. Okada, K. Arai, Y. Hidaka, K. Inaba, T. Muraoka, and M. Okumura.
- Organizer
  the 14the ER and Redox Club meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] Coupling effects of thiol and urea-type groups for promotion of oxidative folding2019
- Author(s)
  M. Matsusaki, S. Okada, K. Inaba, T. Muraoka, and M. Okumura.
- Organizer
  International Symposium on Disordered Proteins, Protein Folding, and Disease-causing Aggregation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] 新規レドックス分子のデザイン法確立と酸化的フォールディングへの応用2019
- Author(s)
  松崎元紀、岡田隼輔、荒井堅太、日高雄二、稲葉謙次、村岡貴博、奥村正樹
- Organizer
  第92回日本生化学大会
- Data Source
  KAKENHI-PROJECT-19J00893
[Presentation] PDIファミリーによるβ2-microglubulinの品質管理機構の解明2019
- Author(s)
  木下岬、金村進吾、松崎元紀、李映昊、稲葉謙次、奥村正樹
- Organizer
  第92回日本生化学大会
- Data Source
  KAKENHI-PROJECT-19J00893

1. 齋尾智英 (80740802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 川越聡一郎 (10980716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 奥村正樹 (50635810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 横山武司 (20719447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 村岡貴博 (70509132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 金村進吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 松尾光一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsusaki Motonori 松崎 元紀

MATSUSAKI Motonori 松崎 元紀

Research Projects

Research Products

Co-Researchers

分泌経路におけるメゾスケール構造体プロファイリングの開拓

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multidimensional endoplasmic reticulum stress sensing by IRE1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞内ストレス応答の情報熱力学的な理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of chaperone activity modulation through promiscuous recognitions

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of disulfide-bonded active oligomerization by an endoplasmic stress sensor IRE1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of ER stress response regulation by PDI family proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Client recognition differences between PDI and ERp46 to guide oxidative folding2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conjugate of Thiol and Guanidyl Units with Oligoethylene Glycol Linkage for Manipulation of Oxidative Protein Folding2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional Interplay between P5 and PDI/ERp72 to Drive Protein Folding.2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Zinc-Dependent Oligomerization of Thermus thermophilus Trigger Factor Chaperone2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ca2+ Regulates ERp57-Calnexin Complex Formation.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PDI Family Members as Guides for Client Folding and Assembly2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 小胞体内におけるMHCの品質管理2020

Author(s)

Journal Title

Matsusaki Motonori 松崎元紀

MATSUSAKI Motonori 松崎元紀