Saio Tomohide 齋尾智英

… Alternative Names

Tomohide Saio 齋尾智英

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Researcher Number	80740802
Other IDs
Affiliation (Current)	2023: 徳島大学, 先端酵素学研究所, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 徳島大学, 先端酵素学研究所, 教授 2016 – 2020: 北海道大学, 理学研究院, 助教 2015: 北海道大学, 理学(系)研究科(研究院), 助教 2015: 北海道大学, 大学院理学研究院, 助教
Review Section/Research Field	Principal Investigator Complex systems / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 43020:Structural biochemistry-related / Transformative Research Areas, Section (II) / Biological Sciences / Molecular biology / Structural biochemistry Except Principal Investigator Bio-related chemistry / Basic Section 34020:Analytical chemistry-related / Broad Section F … More / Medium-sized Section 38:Agricultural chemistry and related fields / Transformative Research Areas, Section (II) / Basic Section 43020:Structural biochemistry-related / Broad Section B Less
Keywords	Principal Investigator NMR / シャペロン / 立体構造 / ダイナミクス / 結合キネティクス / タンパク質フォールディング / 構造変化 / マルチドメインタンパク質 / ランタニドイオン / 高速AFM … More / フォールディング / 過渡的相互作用 / 複合体立体構造 / 立体構造解析 / 常磁性ランタニド / 過渡的構造 / 中性子散乱 / 光技術 / 蛋白質フォールディング / キネティクス / 遅延制御 / ランタノイド / SAXS / ESR / 常磁性ランタノイドイオン / 活性制御 / 細胞壁合成 / 核磁気共鳴法 / 常磁性 / MurD / 常磁性タグ / フォールディング中間体 / 多量体 / 相互作用解析 / 天然変性タンパク質 / LCタンパク質 / 液-液相分離 / トリガーファクター / 二量体 / 速度論 / プロリン異性化 / 結合解離速度 / 分子シャペロン / 常磁性金属 / シャペロン複合体 / 溶液構造 / 電子伝達 / 呼吸鎖 … More Except Principal Investigator タンパク質 / 液-液相分離 / 構造揺らぎ / ナノディスク / シトクロムc / シトクロムc酸化酵素 / 蛍光プローブ / パターン認識 / 相互作用 / メタボロン / 天然ゴム / フラボノイド / 植物特化代謝 / ミスフォールディング / 超分子化学 / フォールディング / 遅延制御 / cross-β polymer / 低複雑性配列 / LLPS / 相分離制御 / 相分離駆動 / 相分離破綻 / アミロイド線維 / LCドメイン / cross-βポリマー / 中間径フィラメント / 相分離シャペロン / 天然変性タンパク質 / 相分離生物学 / 生物学的相分離 / 重水素化 / 蛋白質ダイナミクス / 租視化分子動力学計算 / 中性子準弾性散乱 / MD連携解析 / 蛋白質階層間連携ダイナミクス / 蛋白質重水素化 / 計算機連携解析 / ドメインライゲーション / タンパク質重水素化 / 中性子溶液散乱 / 階層関連ダイナミクス / 分子動力学計算 / ドメイン選択重水素化 / 階層間連携ダイナミクス / 中性子散乱 / 新世代中性子構造生物学 / 電子伝達複合体 / 構造的揺らぎ / 脱水和 / 電子伝達経路 / TCS / 電子伝達 / ミトコンドリア呼吸鎖 / 電子伝達系 / シトクロム酸化酵素 / 生体膜モデル / ドッキングシミュレーション / MSP / ヘム / 電子伝達反応 Less

植物特化代謝における超分子的代謝マシナリの形成：多元構造解析による統合的理解
- Principal Investigator
  
  中山亨
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Tohoku University
Molecular dissection of plant specialized metabolism machineries
- Principal Investigator
  
  中山亨
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section F
- Research Institution
  Tohoku University
Stratification of Protein Aggregation States based on Pattern Recognition for Screening Factors Controlling Phase Separation
- Principal Investigator
  
  冨田峻介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Mechanism of chaperone activity modulation through promiscuous recognitionsPrincipal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokushima
光技術と構造生物学の融合による過渡構造解析Principal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokushima
Organization of kinetics-driven supramolecular chemistry
- Principal Investigator
  
  村岡貴博
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tokyo University of Agriculture and Technology
Unraveling the mechanism of kinetic regulation in biomolecular foldingPrincipal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokushima
Structural basis for recognition and regulation of protein folding intermediate by molecular chaperones in the endoplasmic reticulumPrincipal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokushima
Regulatory mechanism of biological phase separation
- Principal Investigator
  
  森英一朗
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Nara Medical University
Structural basis for chaperone network mediated by semi-specific recognitionsPrincipal Investigator
- Principal Investigator
  
  SAIO Tomohide
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokushima
  Hokkaido University
相分離を介したシグナル伝達制御の構造基盤Principal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Neutron Structural Biology for New Generation
- Principal Investigator
  
  杉山正明
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section B
- Research Institution
  Kyoto University
分子シャペロンの基質選択と活性発現における動的構造基盤Principal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
NMRを主体としたタンパク質構造推移解析のための複合手法の開発と応用Principal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Dynamic Structural Characterization of Electron Transfer Complex in Respiratory Chain of Mitochondria and Its Electron Transfer Regulation Mechanism
- Principal Investigator
  
  Ishimori koichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Hokkaido University
Analysis of respiratory electron transport chain using the paramagnetic probesPrincipal Investigator
- Principal Investigator
  
  SAIO Tomohide
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
  Molecular biology
- Research Institution
  Hokkaido University
NMRを主体としたタンパク質構造推移解析のための複合手法の開発と応用Principal Investigator
- Principal Investigator
  
  齋尾智英
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Functional and Structural Characterization of Electron Transfer Reactions in Mitochondria Respiratory Chain Utilizing Nanodisc
- Principal Investigator
  
  Ishimori Koichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Hokkaido University

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] Experimental Approaches of NMR Spectroscopy: Methodology and Application to Life Science and Materials Science, Chapter 8 Structural study of proteins by paramagnetic lanthanide probe methods2017
- Author(s)
  Tomohide Saio and Fuyuhiko Inagaki
- Total Pages
  636
- Publisher
  Springer
- ISBN
  9789811059667
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Book] Advanced Methods in Structural Biology, Chapter 17, NMR Structural Biology Using Paramagnetic Lanthanide Probe.2016
- Author(s)
  Tomohide Saio, Fuyuhiko Inagaki.
- Total Pages
  340
- Publisher
  Tokyo: Springer Japan
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Book] Advanced Methods in Structural Biology, Chapter 20, NMR Structural Biology using Paramagnetic Lanthanide Probe2016
- Author(s)
  Tomohide Saio, Fuyuhiko Inagaki
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Journal Article] Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex2021
- Author(s)
  Rizzolo Kamran、Yu Angela Yeou Hsiung、Ologbenla Adedeji、Kim Sa-Rang、Zhu Haojie、Ishimori Koichiro、Thibault Guillaume、Leung Elisa、Zhang Yi Wen、Teng Mona、Haniszewski Marta、Miah Noha、Phanse Sadhna、Minic Zoran、Lee Sukyeong、Caballero Julio Diaz、Babu Mohan、Tsai Francis T. F.、Saio Tomohide、Houry Walid A.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 281-281
- DOI
  10.1038/s41467-020-20553-x
- NAID
  120007186802
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Journal Article] Conformational dynamics of a multidomain protein by neutron scattering and computational analysis2021
- Author(s)
  Nakagawa Hiroshi、Saio Tomohide、Nagao Michihiro、Inoue Rintaro、Sugiyama Masaaki、Ajito Satoshi、Tominaga Taiki、Kawakita Yukinobu
- Journal Title
  
  Biophysical Journal
  
  Volume: 120 Issue: 16 Pages: 3341-3354
- DOI
  10.1016/j.bpj.2021.07.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H02944, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-19KK0071
[Journal Article] C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers2021
- Author(s)
  Nanaura Hitoki、Aiba Yuichiro、Nakanishi Mari、Shiota Tomo、Hibino Masaki、Kikuchi Sotaro、Nagata Riko、Morikawa Naritaka、Iguchi Naohiko、Kiriyama Takao、Nagamori Shushi、Sugie Kazuma、Saio Tomohide、Yoshizawa Takuya、Mori Eiichiro et al.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 5301-5301
- DOI
  10.1038/s41467-021-25560-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-19K16060, KAKENHI-PROJECT-20K16583, KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-18H03984, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-20K06493, KAKENHI-PROJECT-20K06527, KAKENHI-PROJECT-20K06569, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-21K15032, KAKENHI-PROJECT-19KK0071, KAKENHI-PROJECT-22KJ0024
[Journal Article] Deuteration Aiming for Neutron Scattering2021
- Author(s)
  Okuda Aya、Inoue Rintaro、Morishima Ken、Saio Tomohide、Yunoki Yasuhiro、Yagi-Utsumi Maho、Yagi Hirokazu、Shimizu Masahiro、Sato Nobuhiro、Urade Reiko、Kato Koichi、Sugiyama Masaaki
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 18 Issue: 0 Pages: 16-27
- DOI
  10.2142/biophysico.bppb-v18.003
- NAID
  130008000165
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-20K22629, KAKENHI-PROJECT-19KK0071, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-18J21063, KAKENHI-PROJECT-19K16088
[Journal Article] Zinc-Dependent Oligomerization of Thermus thermophilus Trigger Factor Chaperone2021
- Author(s)
  Zhu Haojie、Matsusaki Motonori、Sugawara Taiga、Ishimori Koichiro、Saio Tomohide
- Journal Title
  
  Biology
  
  Volume: 10 Issue: 11 Pages: 1106-1106
- DOI
  10.3390/biology10111106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15969, KAKENHI-PLANNED-19H05769, KAKENHI-PROJECT-18H05229
[Journal Article] Conformational ensemble of a multidomain protein explored by Gd3+ electron paramagnetic resonance2021
- Author(s)
  Saio, T., Hiramatsu, S., Asada, M., Nakagawa, H., Shimizu, K., Kumeta, H., Nakamura, T., Ishimori, K.
- Journal Title
  
  Biophys. J.
  
  Volume: 120 Issue: 15 Pages: 2943-2951
- DOI
  10.1016/j.bpj.2021.06.033
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05769, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H02944
[Journal Article] Biological phase separation: cell biology meets biophysics2020
- Author(s)
  Takuya Yoshizawa、Ryu-Suke Nozawa、Tony Z. Jia、Tomohide Saio、Eiichiro Mori
- Journal Title
  
  Biophysical Reviews
  
  Volume: 12 Issue: 2 Pages: 519-539
- DOI
  10.1007/s12551-020-00680-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16060, KAKENHI-PROJECT-18K14354, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H03190, KAKENHI-PUBLICLY-19H04945
[Journal Article] Dynamics of proteins with different molecular structures under solution condition2020
- Author(s)
  Inoue Rintaro、Oda Takashi、Nakagawa Hiroshi、Tominaga Taiki、Saio Tomohide、Kawakita Yukinobu、Shimizu Masahiro、Okuda Aya、Morishima Ken、Sato Nobuhiro、Urade Reiko、Sato Mamoru、Sugiyama Masaaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 21678-21678
- DOI
  10.1038/s41598-020-78311-4
- NAID
  120007193758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06527, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-19KK0071, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-18H02391, KAKENHI-PROJECT-20H02944, KAKENHI-PROJECT-19K16088
[Journal Article] 検出技術：天然変性蛋白質の構造生物学2020
- Author(s)
  小田　隆、齋尾智英
- Journal Title
  
  生物工学
  
  Volume: 98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05229
[Journal Article] Distance Distribution between Two Iodine Atoms Derived from Small-Angle X-ray Scattering Interferometry for Analyzing a Conformational Ensemble of Heavy Atom-Labeled Small Molecules2020
- Author(s)
  Taguchi Yuya、Saio Tomohide、Kohda Daisuke
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 11 Issue: 14 Pages: 5451-5456
- DOI
  10.1021/acs.jpclett.0c01107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05229
[Journal Article] Toxic PR poly-dipeptides encoded by the C9orf72 repeat expansion target Kapβ2 and dysregulate phase separation of low-complexity domains.2019
- Author(s)
  Nanaura H, Kawamukai H, Fujiwara A, Uehara T, Nakanishi M, Shiota T, Hibino M, Aiba Y, Wiriyasermkul P, Kikuchi S, Nagata R, Matsubayashi M, Nagamori S, Shoji O, Ishimori K, Matsumura H, Sugie K, Saio T*, Yoshizawa T*, Mori E
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/812099
- Open Access
- Data Source
  KAKENHI-PROJECT-19K21306, KAKENHI-PUBLICLY-19H04945
[Journal Article] Accelerating structural life science by paramagnetic lanthanide probe methods2019
- Author(s)
  Saio Tomohide、Ishimori Koichiro
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: － Issue: 2 Pages: 129332-129332
- DOI
  10.1016/j.bbagen.2019.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05657, KAKENHI-PROJECT-18H05229, KAKENHI-PUBLICLY-17H05867, KAKENHI-PLANNED-19H05769, KAKENHI-PUBLICLY-19H04945
[Journal Article] Dynamic assembly of protein disulfide isomerase in catalysis of oxidative folding2019
- Author(s)
  Okumura Masaki、Noi Kentaro、Kanemura Shingo、Kinoshita Misaki、Saio Tomohide、Inoue Yuichi、Hikima Takaaki、Akiyama Shuji、Ogura Teru、Inaba Kenji
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 5 Pages: 499-509
- DOI
  10.1038/s41589-019-0268-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05657, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-17H06521, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-18H03978, KAKENHI-PLANNED-26116005, KAKENHI-PUBLICLY-17H05867, KAKENHI-PUBLICLY-19H04945
[Journal Article] Polyethylene glycol promotes autoxidation of cytochrome c2018
- Author(s)
  Sato Wataru、Uchida Takeshi、Saio Tomohide、Ishimori Koichiro
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1862 Issue: 6 Pages: 1339-1349
- DOI
  10.1016/j.bbagen.2018.03.010
- NAID
  120006585774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04173, KAKENHI-PROJECT-17J01146
[Journal Article] Oligomerization of a molecular chaperone modulates its activity2018
- Author(s)
  Saio Tomohide、Kawagoe Soichiro、Ishimori Koichiro、Kalodimos Charalampos G
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.35731
- NAID
  120006581597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05657, KAKENHI-PUBLICLY-17H05867
[Journal Article] Structural insight into proline cis/trans isomerization of unfolded proteins catalyzed by the trigger factor chaperone2018
- Author(s)
  Kawagoe Soichiro、Nakagawa Hiroshi、Kumeta Hiroyuki、Ishimori Koichiro、Saio Tomohide
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 39 Pages: 15095-15106
- DOI
  10.1074/jbc.ra118.003579
- NAID
  120006585777
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05657, KAKENHI-PROJECT-18H05229, KAKENHI-PUBLICLY-17H05867
[Journal Article] Investigation of the Redox-dependent Modulation of Structure and Dynamics in Human Cytochrome c2016
- Author(s)
  Imai, M., Saio, T., Kumata, H., Uchida, T., Inagaki, F., Ishimori, K.
- Journal Title
  
  Biochemical and Biophysical Research Communication
  
  Volume: 469 Pages: 978-984
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25288072
[Journal Article] Energetic Mechanism of Cytochrome c - Cytochrome c Oxidase Electron Transfer Complex Formation under Turnover Conditions Revealed by Mutational Effects and Docking Simulation2016
- Author(s)
  W. Sato, S. Hitaoka, K. Inoue, M. Imai, T. Saio, T. Uchida, K. Shinzawa-Itoh, S. Yoshikawa, K. Yoshizawa, and K. Ishimori
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 29 Pages: 15320-15331
- DOI
  10.1074/jbc.m115.708065
- NAID
  120006324913
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24109014, KAKENHI-PROJECT-26291033, KAKENHI-PROJECT-15K13710, KAKENHI-PROJECT-15K20829
[Journal Article] Investigation of the redox-dependent modulation of structure and dynamics in human cytochrome c.2016
- Author(s)
  Imai M, Saio T, Kumeta H, Uchida T, Inagaki F, Ishimori K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469 Issue: 4 Pages: 978-984
- DOI
  10.1016/j.bbrc.2015.12.079
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K20829
[Journal Article] Ligand-driven conformational changes of MurD visualized by paramagnetic NMR.2015
- Author(s)
  Saio T, Ogura K, Kumeta H, Kobashigawa Y, Shimizu K, Yokochi M, Kodama K, Yamaguchi H, Tsujishita H, Inagaki F.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 16685-16685
- DOI
  10.1038/srep16685
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01624, KAKENHI-PROJECT-15H05183
[Presentation] 新規光応答性シャペロンの創製とそれを利用した液-液相分離の制御2022
- Author(s)
  太田帆香，川越聡一郎，松崎元紀，久米田博之，石森浩一郎，齋尾智英
- Organizer
  2021年度生物物理学会北海道支部-東北支部合同例会
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] タンパク質液滴の形成・制御・破綻の分子メカニズム2022
- Author(s)
  齋尾智英
- Organizer
  日本化学会第102春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Mechanistic insight into chaperone-mediated protein homeostasis2021
- Author(s)
  Tomohide Saio
- Organizer
  The 16th International Symposium of the Institute Network for Biomedical Sciences & KEY FORUM 2021 International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Mechanistic insights into a molecular chaperone in protein folding and degradation2021
- Author(s)
  Tomohide Saio
- Organizer
  2021 virtual Cold Spring Harbor Asia Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] ALS-associated factor PRn inhibit the function of KapB22021
- Author(s)
  Honoka Kawamukai, Koichiro Ishimori, Tomohide Saio
- Organizer
  The 16th International Symposium of the Institute Network for Biomedical Sciences & KEY FORUM 2021 International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] NMR investigation of molecular chaperones manipulating protein folding2021
- Author(s)
  Tomohide Saio
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Structural and kinetic insights into a molecular chaperone for protein folding, translocation, and degradation2021
- Author(s)
  Tomohide Saio
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Large-scale conformational distribution of a multi-domain protein enzyme investigated by NMR and EPR2021
- Author(s)
  Tomohide Saio
- Organizer
  第59回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] 多量体形成を介したシャぺロンの機能制御2021
- Author(s)
  齋尾智英
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] ストレス応答を制御する転写因子Heat shock factor1の酸化還元依存的な相転移2021
- Author(s)
  川越聡一郎、松崎元紀、石森浩一郎、齋尾智英
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] 常磁性金属と分子シャペロン2020
- Author(s)
  齋尾智英
- Organizer
  2020年度日本分光学会NMR分光部会集中講義
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] シャペロンから理解する細胞内タンパク質の動態制御メカニズム2020
- Author(s)
  齋尾智英
- Organizer
  第93回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Exploiting paramagnetic metal ions for protein structural study in solution2020
- Author(s)
  齋尾智英, 石森浩一郎
- Organizer
  第 58 回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] On and off between molecular chaperones and clients: Appropriate distance and timing for protein folding2020
- Author(s)
  Tomohide Saio
- Organizer
  21st Hokudai-RIES International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] 細胞内恒常性維持を担うシャペロンの動的構造基盤と制御2019
- Author(s)
  齋尾智英
- Organizer
  日本生化学会北海道支部第56 回支部例会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] Applications of paramagnetic lanthanide ions in NMR and ESR2019
- Author(s)
  Tomohide Saio
- Organizer
  International IPR Seminar -Open up a new era of structural biology with advanced NMR study-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] Applications of paramagnetic lanthanide ions in NMR and ESR2019
- Author(s)
  T. Saio
- Organizer
  International IPR Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] 細胞内恒常性維持を担うシャペロンの動的構造基盤と制御2019
- Author(s)
  齋尾智英
- Organizer
  日本化学会北海道支部奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019
- Author(s)
  T.Saio
- Organizer
  8th Asia-Pacific NMR Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Protein structure and dynamics by solution NMR2019
- Author(s)
  Tomohide Saio
- Organizer
  ASUKA Symposium 2019
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] タンパク質フォールディングにおける分子シャペロンの機能とメカニズム: 立体構造と速度論からのアプローチ2019
- Author(s)
  齋尾智英
- Organizer
  第92 回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] 金属イオンを用いたSAXSとNMRによるマルチドメインタンパク質の動的構造解析2019
- Author(s)
  齋尾智英
- Organizer
  PF研究会 -BioSASが拓く生体高分子の分子間相互作用解析の最前線-
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] 金属イオンを用いたSAXSとNMRによるマルチドメイン蛋白質の動的構造解析2019
- Author(s)
  齋尾智英
- Organizer
  PF研究会「BioSASが拓く生体高分子の分子間相互作用解析の最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Exploring conformational states of a protein enzyme using paramagnetic lanthanide ions2019
- Author(s)
  T.Saio
- Organizer
  Biometal Science 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] QENS of protein solutions measured by the TOF near Backscattering Spectrometer DNA2019
- Author(s)
  H. Nakagawa, T. Saio, T. Oda, M. Sato, R. Inoue, M. Sugiyama, T. Tominaga, Y. Kawakita
- Organizer
  J-PARC Symposium 2019
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Exploring conformational states of a protein enzyme using paramagnetic lanthanide ions2019
- Author(s)
  Tomohide Saio
- Organizer
  Biometal Science 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] 低複雑性タンパク質の液-液相分離の制御と破綻のメカニズム: NMRによる解析2019
- Author(s)
  齋尾智英
- Organizer
  第 4 回 LLPS 研究会・ASUKA 若手交流会 2019
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019
- Author(s)
  Tomohide Saio
- Organizer
  8th Asia-Pacific NMR Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019
- Author(s)
  Tomohide Saio, Soichiro Kawagoe, Charalampos G Kalodimos, Koichiro Ishimori
- Organizer
  8TH Asia-Pacific NMR 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] Structural and kinetic basis for functional modulation of a molecular chaperone2019
- Author(s)
  Tomohide Saio, Soichiro Kawagoe, Charalampos G Kalodimos, Koichiro Ishimori
- Organizer
  8TH Asia-Pacific NMR 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05657
[Presentation] Structure and dynamics of molecular chaperones in protein folding, holding, and degradation2019
- Author(s)
  齋尾智英
- Organizer
  第2回タンパク質可塑性についての研究会－タンパク質と人工分子のダイナミクスと機能相関－
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] 低複雑性蛋白質の液-液相分離の制御と破綻のメカニズム: NMRによる解析2019
- Author(s)
  齋尾智英
- Organizer
  第4回LLPS研究会・ASUKA若手交流会2019
- Invited
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Structural and kinetic insights into molecular chaperones2019
- Author(s)
  T. Saio
- Organizer
  International Symposium on Protein Folding and Misfolding-related Aggregation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05229
[Presentation] Structural and kinetic insights into molecular chaperones2019
- Author(s)
  Tomohide Saio
- Organizer
  International Symposium on Protein Folding and Misfolding-related Aggregation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04945
[Presentation] Diverse activities of molecular chaperones through non-selective binding2018
- Author(s)
  Tomohide Saio, Charalampos Kalodimos, Koichiro Ishimori
- Organizer
  日本生物物理学会第56回年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] Modulation of chaperone activity by oligomerization2018
- Author(s)
  Tomohide Saio, Soichiro Kawagoe, Koichiro Ishimori, Charalampos G. Kalodimos
- Organizer
  28th International Conference on Magnetic Resonance in Biological Systems (ICMRBS)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] Diverse activities of molecular chaperones through non-selective binding2018
- Author(s)
  Tomohide Saio, Charalampos Kalodimos, Koichiro Ishimori
- Organizer
  日本生物物理学会第56回年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05657
[Presentation] パルスEPRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2018
- Author(s)
  平松蒼野，齋尾智英，浅田瑞枝，瀧下俊平，中村敏和，石森浩一郎
- Organizer
  第55回生化学会北海道支部例会
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] Structural and kinetic insights into chaperone activities of Trigger Factor.2018
- Author(s)
  Tomohide Saio
- Organizer
  International Symposium -Proteins: from the Cradle to the Grave-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] パルスEPRとGd3+を用いたマルチドメイン蛋白質MurDの立体構造変化の解析2018
- Author(s)
  平松蒼野，齋尾智英，浅田瑞枝，瀧下俊平，中村敏和，石森浩一郎
- Organizer
  第57回電子スピンサイエンス学会年会(SEST2018)
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] Modulation of chaperone activity by oligomerization2018
- Author(s)
  Tomohide Saio, Soichiro Kawagoe, Koichiro Ishimori, Charalampos G. Kalodimos
- Organizer
  28th International Conference on Magnetic Resonance in Biological Systems (ICMRBS)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05657
[Presentation] Structural and kinetic insights into chaperone activities of Trigger Factor.2018
- Author(s)
  Tomohide Saio
- Organizer
  International Symposium -Proteins: from the Cradle to the Grave-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05657
[Presentation] Exploring conformational equilibria of a multi-domain protein MurD by paramagnetic lanthanide probe in NMR and EPR2017
- Author(s)
  Tomohide Saio, Soya Hiramatsu, Mizue Asada, Shunpei Takishita, Toshikazu Nakamura, Koichiro Ishimori
- Organizer
  第17回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] パルスESRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2017
- Author(s)
  平松蒼野，齋尾智英，浅田瑞枝，瀧下俊平，稲垣冬彦，中村敏和，石森浩一郎
- Organizer
  第17回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター (宮城県・仙台市)
- Year and Date
  2017-06-20
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Presentation] パルスESRとガドリニウムタグを用いたマルチドメイン蛋白質MurDの構造変化解析2017
- Author(s)
  平松蒼野，齋尾智英，浅田瑞枝，瀧下俊平，稲垣冬彦，中村敏和，石森浩一郎
- Organizer
  化学系学協会北海道支部2017冬季研究発表会
- Place of Presentation
  北海道大学 (北海道・札幌市)
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Presentation] パルスESRとガドリニウムタグを用いたマルチドメイン蛋白質MurDの構造変化解析2017
- Author(s)
  平松蒼野, 齋尾智英, 浅田瑞枝, 瀧下俊平, 稲垣冬彦, 中村敏和, 石森浩一郎
- Organizer
  化学系学協会北海道支部2017冬季研究発表会
- Place of Presentation
  北海道大学 (北海道・札幌市)
- Data Source
  KAKENHI-PROJECT-15K20829
[Presentation] Exploring conformational equilibria of a multi-domain protein MurD by paramagnetic lanthanide probe in NMR and EPR2017
- Author(s)
  Tomohide Saio, Soya Hiramatsu, Mizue Asada, Shunpei Takishita, Toshikazu Nakamura, Koichiro Ishimori
- Organizer
  第17回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター (宮城県・仙台市)
- Year and Date
  2017-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-15K20829
[Presentation] パルスESRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2017
- Author(s)
  平松蒼野，齋尾智英，浅田瑞枝，瀧下俊平，中村敏和，石森浩一郎
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] マルチドメインタンパク質における構造アンサンブルと各構造の存在比の解析2017
- Author(s)
  瀧下俊平, 齋尾智英, 平松蒼野, 久米田博之, 清水和美, 石森浩一郎
- Organizer
  第56回 NMR討論会
- Data Source
  KAKENHI-PUBLICLY-17H05867
[Presentation] パルスESRとGd3+を用いたマルチドメイン蛋白質MurDの構造変化解析2017
- Author(s)
  平松蒼野, 齋尾智英, 浅田瑞枝, 瀧下俊平, 稲垣冬彦, 中村敏和, 石森浩一郎
- Organizer
  第17回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター (宮城県・仙台市)
- Year and Date
  2017-06-20
- Data Source
  KAKENHI-PROJECT-15K20829
[Presentation] Exploring conformational equilibria of a multi-domain protein MurD by paramagnetic lanthanide probe in NMR and EPR2017
- Author(s)
  Tomohide Saio, Soya Hiramatsu, Mizue Asada, Shunpei Takishita, Toshikazu Nakamura, Koichiro Ishimori
- Organizer
  第17回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター (宮城県・仙台市)
- Year and Date
  2017-06-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Presentation] Dynamic Structural Changes Of A Multi-Domain Protein Probed By Paramagnetic NMR2016
- Author(s)
  Shumpei Takishita, Tomohide Saio, Hiroyuki Kumeta, Fuyuhiko Inagaki, Koichiro Ishimori
- Organizer
  The XXVIIth International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  国立京都国際会館 (京都府・京都市)
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Presentation] マルチドメインタンパク質の動的構造変化の解析への常磁性ランタノイドプローブを用いたNMR法の応用2016
- Author(s)
  瀧下俊平, 齋尾智英, 久米田博之, 稲垣冬彦, 石森浩一郎
- Organizer
  日本生物物理学会北海道支部例会
- Place of Presentation
  北海道大学 (北海道札幌市)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Presentation] ランタノイドイオンを用いたマルチドメインタンパク質の動的解析2016
- Author(s)
  瀧下俊平，齋尾智英，久米田博之，稲垣冬彦，石森浩一郎
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市)
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PUBLICLY-15H01624
[Presentation] Visualizing conformational changes of MurD by paramagnetic lanthanide probe2016
- Author(s)
  Tomohide Saio
- Organizer
  The 5th International Symposium on Drug Discovery and Design by NMR
- Place of Presentation
  理化学研究所横浜事業所 (神奈川県・横浜市)
- Year and Date
  2016-08-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01624

1. Ishimori Koichiro (20192487)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. Takeshi Uchida (30343742)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 井上倫太郎 (80563840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 奥村正樹 (50635810)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 森英一朗 (70803659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 中山亨 (80268523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 和氣駿之 (10793705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 田中良和 (20374225)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 山下哲 (70361186)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 竹下浩平 (80346808)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 杉山正明 (10253395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 中川洋 (20379598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 矢木真穂 (40608999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 富永大輝 (50513694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 佐藤衛 (60170784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 苙口友隆 (90589821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小田隆 (00573164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. 金村進吾 (50803178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 吉澤拓也 (50779056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 菊池壮太郎 (90866386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 松崎元紀 (90817040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 川越聡一郎 (10980716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 村岡貴博 (70509132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中曽根祐介 (00613019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 高橋征司 (90343061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 戸澤譲 (90363267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 冨田峻介 (50726817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 菅井祥加 (10905566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 七浦仁紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 吉澤一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 杉江和馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 桐山敬生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 塩田智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 井口直彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saio Tomohide 齋尾 智英

Tomohide Saio 齋尾 智英

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Mechanism of chaperone activity modulation through promiscuous recognitionsPrincipal Investigator

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光技術と構造生物学の融合による過渡構造解析Principal Investigator

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Unraveling the mechanism of kinetic regulation in biomolecular foldingPrincipal Investigator

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Structural basis for recognition and regulation of protein folding intermediate by molecular chaperones in the endoplasmic reticulumPrincipal Investigator

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Structural basis for chaperone network mediated by semi-specific recognitionsPrincipal Investigator

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相分離を介したシグナル伝達制御の構造基盤Principal Investigator

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分子シャペロンの基質選択と活性発現における動的構造基盤Principal Investigator

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NMRを主体としたタンパク質構造推移解析のための複合手法の開発と応用Principal Investigator

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Saio Tomohide 齋尾智英

Tomohide Saio 齋尾智英