Takeda Daisuke 武田大介

Researcher Number	80755637
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 神戸大学, 医学部附属病院, 助教 2019: 神戸大学, 医学部附属病院, 特定助教 2017 – 2018: 神戸大学, 医学部附属病院, 医員 2016: 神戸大学, 医学研究科, 医学研究員
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 口腔がん / がん悪液質 / インスリン抵抗性 / ミトコンドリア機能不全 / 筋肉量減少 / 骨格筋萎縮 / 経皮的炭酸ガス療法 / 歯学 / 癌 / 頸部リンパ節転移 … More / リンパ管新生能因子 / 疾患特異的生存率 / 分化度 / 低酸素 / 幹細胞性因子 / 癌幹細胞 / 口腔癌 … More Except Principal Investigator 口腔癌 / 炭酸ガス / 癌関連線維芽細胞 / 副作用 / 放射線抵抗性 / 低酸素環境 / 放射線治療 / 治療抵抗性 / 放射線 Less

がん悪液質を想定した筋肉量減少に対するミトコンドリア機能改善を介した新規治療法Principal Investigator
- Principal Investigator
  
  武田大介
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kobe University
ミトコンドリアの正常化と癌関連線維芽細胞の再教育を目指した新規口腔癌治療法の開発
- Principal Investigator
  
  長谷川巧実
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kobe University
がん悪液質に着目した口腔がん新規治療法の検討Principal Investigator
- Principal Investigator
  
  武田大介
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kobe University
Development of cancer therapies to improve resistance and reduce side effects
- Principal Investigator
  
  Hasegawa Takumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kobe University
Examination of metastasis suppression effect focusing on tumor microenvironment around cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  Takeda Daisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Transcutaneous carbon dioxide suppresses skeletal muscle atrophy in a mouse model of oral squamous cell carcinoma2024
- Author(s)
  Sasaki Aki、Takeda Daisuke、Kawai Hotaka、Tadokoro Yoshiaki、Murakami Aki、Yatagai Nanae、Arimoto Satomi、Nagatsuka Hitoshi、Akashi Masaya、Hasegawa Takumi
- Journal Title
  
  PLOS ONE
  
  Volume: 19 Issue: 4 Pages: 1-13
- DOI
  10.1371/journal.pone.0302194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18724
[Journal Article] Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model2023
- Author(s)
  Tadokoro Yoshiaki、Takeda Daisuke、Murakami Aki、Yatagai Nanae、Saito Izumi、Arimoto Satomi、Kakei Yasumasa、Akashi Masaya、Hasegawa Takumi
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 8 Pages: e0290357-e0290357
- DOI
  10.1371/journal.pone.0290357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10193
[Journal Article] Relationship of Mitochondrial-Related Protein Expression with the Differentiation, Metastasis, and Poor Prognosis of Oral Squamous Cell Carcinoma2023
- Author(s)
  Murakami Aki、Takeda Daisuke、Hirota Junya、Saito Izumi、Amano-Iga Rika、Yatagai Nanae、Arimoto Satomi、Kakei Yasumasa、Akashi Masaya、Hasegawa Takumi
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 16 Pages: 4071-4071
- DOI
  10.3390/cancers15164071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10193
[Journal Article] The Efficacy of Carbon Dioxide Paste in Alleviating Pain in Patients After Neck Dissection: Protocol for a Double-Blinded, Randomized Controlled Trial2023
- Author(s)
  Tadokoro Yoshiaki、Takeda Daisuke、Saito Izumi、Yatagai Nanae、Kakei Yasumasa、Akashi Masaya、Hasegawa Takumi
- Journal Title
  
  JMIR Research Protocols
  
  Volume: 12 Pages: e50500-e50500
- DOI
  10.2196/50500
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K21014, KAKENHI-PROJECT-22K10193
[Journal Article] Exploratory clinical trial to evaluate the efficacy and safety of carbon dioxide paste in healthy people2022
- Author(s)
  Yatagai Nanae、Hasegawa Takumi、Kyotani Katsusuke、Noda Tomohiro、Amano Rika、Saito Izumi、Arimoto Satomi、Takeda Daisuke、Kakei Yasumasa、Akashi Masaya
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 29 Pages: e29511-e29511
- DOI
  10.1097/md.0000000000029511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10193, KAKENHI-PROJECT-22K21014, KAKENHI-PROJECT-19K19156
[Journal Article] Local application of a transcutaneous carbon dioxide paste prevents excessive scarring and promotes muscle regeneration in a bupivacaine‐induced rat model of muscle injury2022
- Author(s)
  Hirota Junya、Hasegawa Takumi、Inui Atsuyuki、Takeda Daisuke、Amano‐Iga Rika、Yatagai Nanae、Saito Izumi、Arimoto Satomi、Akashi Masaya
- Journal Title
  
  International Wound Journal
  
  Volume: 20 Issue: 4 Pages: 1151-1159
- DOI
  10.1111/iwj.13974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10193, KAKENHI-PROJECT-22K21014, KAKENHI-PROJECT-19K19156
[Journal Article] Local Application of Transcutaneous Carbon Dioxide Paste Decreases Inflammation and Accelerates Wound Healing2021
- Author(s)
  Amano-Iga Rika、Hasegawa Takumi、Takeda Daisuke、Murakami Aki、Yatagai Nanae、Saito Izumi、Arimoto Satomi、Kakei Yasumasa、Sakakibara Akiko、Akashi Masaya
- Journal Title
  
  Cureus
  
  Volume: 13
- DOI
  10.7759/cureus.19518
- NAID
  120007179182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09788, KAKENHI-PROJECT-19K19156
[Journal Article] Transcutaneous Carbon Dioxide Decreases Immunosuppressive Factors in Squamous Cell Carcinoma In Vivo2021
- Author(s)
  Yatagai Nanae、Hasegawa Takumi、Amano Rika、Saito Izumi、Arimoto Satomi、Takeda Daisuke、Kakei Yasumasa、Akashi Masaya
- Journal Title
  
  BioMed Research International
  
  Volume: 5568428 Issue: 1 Pages: 1-9
- DOI
  10.1155/2021/5568428
- NAID
  120007125723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09788, KAKENHI-PROJECT-19K19156
[Journal Article] Induced Pluripotent Stem Cell-related Genes Correlate With Poor Prognoses of Oral Squamous Cell Carcinoma.2019
- Author(s)
  Muraki Y, Hasegawa T, Takeda D, Ueha T, Iwata E, Saito I, Amano R, Sakakibara A, Akashi M, Komori T.
- Journal Title
  
  ANTICANCER RESEARCH
  
  Volume: 39 Issue: 3 Pages: 1205-1216
- DOI
  10.21873/anticanres.13231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20575
[Journal Article] Lymphangiogenesis and Lymph Node Metastasis in Oral Squamous Cell Carcinoma.2018
- Author(s)
  Arimoto S, Hasegawa T, Takeda D, Saito I, Amano R, Akashi M, Komori T.
- Journal Title
  
  ANTICANCER RESEARCH
  
  Volume: 38 Issue: 11 Pages: 6157-6162
- DOI
  10.21873/anticanres.12968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20575
[Journal Article] Induced Pluripotent-stem-cell Related Genes Contribute to De-differentiation in Oral Squamous Cell Carcinoma.2017
- Author(s)
  Takeda D, Hasegawa T, Ueha T, Iwata E, Harada R, Sakakibara A, Kawamoto T, Minamikawa T, Sakai Y, Komori T.
- Journal Title
  
  Anticancer Res.
  
  Volume: 37 Issue: 3 Pages: 1075-1082
- DOI
  10.21873/anticanres.11419
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K20575
[Presentation] 口腔扁平上皮癌におけるミトコンドリア関連タンパク質発現と分化、転移、予後との関係．2023
- Author(s)
  村上明希，長谷川巧実，武田大介，廣田純也，黒澤泉，伊賀利香，八谷奈苗，有本智美，筧康正，明石昌也
- Organizer
  第68回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K10193
[Presentation] がん関連線維芽細胞マーカーの発現抑制に着目した炭酸ガス吸収療法による抗腫瘍効果の検討.2023
- Author(s)
  田所慶誠, 長谷川巧実, 廣田純也, 村上明希, 佐々木亜紀, 武田大介, 筧康正, 明石昌也.
- Organizer
  第68回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K10193
[Presentation] 局所的炭酸ガス投与による口腔扁平上皮癌の腫瘍免疫抑制に対する改善効果2022
- Author(s)
  八谷奈苗，長谷川巧実，武田大介，筧　康正，榊原晶子，明石昌也．
- Organizer
  第76回日本口腔科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K10193
[Presentation] 炭酸ガスを使用した効率的な低酸素環境改善による口腔癌の新規治療法の開発と治療抵抗性の改善効果2019
- Author(s)
  長谷川巧実、武田大介、斉藤　泉、岩田英治、筧康正、榊原晶子、明石昌也、南川勉、古森孝英
- Organizer
  第37回日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-18K09788
[Presentation] 口腔扁平上皮癌におけるリンパ管新生とリンパ節転移2019
- Author(s)
  有本智美・長谷川巧実・八谷奈苗・天野利香・齊藤泉・武田大介・明石昌也
- Organizer
  第64回(公社)日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K20575
[Presentation] 口腔扁平上皮癌における人工多能性幹細胞関連因子の発現について2019
- Author(s)
  武田大介・長谷川巧実・江崎友美・榊原晶子・明石昌也・南川勉・古森孝英
- Organizer
  第37回(一社)日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K20575
[Presentation] 口腔扁平上皮癌におけるiPS細胞関連因子の発現率と予後の関連性2018
- Author(s)
  江崎友美・長谷川巧実・武田大介・筧　康正・明石昌也・南川　勉・古森孝英
- Organizer
  第63回(公社)日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K20575
[Presentation] 効率的な低酸素環境改善による口腔癌の新規治療法の開発と治療抵抗性の改善効果2018
- Author(s)
  長谷川巧実、武田大介、斉藤泉、岩田英治、筧　康正、榊原晶子、明石昌也、南川勉、古森孝英
- Organizer
  第63回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-18K09788

1. Hasegawa Takumi (50546497)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. 明石昌也 (40597168)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. 榊原晶子 (00569866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Takeda Daisuke 武田 大介

Research Projects

Research Products

Co-Researchers

がん悪液質を想定した筋肉量減少に対するミトコンドリア機能改善を介した新規治療法Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミトコンドリアの正常化と癌関連線維芽細胞の再教育を目指した新規口腔癌治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん悪液質に着目した口腔がん新規治療法の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of cancer therapies to improve resistance and reduce side effects

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of metastasis suppression effect focusing on tumor microenvironment around cancer stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Transcutaneous carbon dioxide suppresses skeletal muscle atrophy in a mouse model of oral squamous cell carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relationship of Mitochondrial-Related Protein Expression with the Differentiation, Metastasis, and Poor Prognosis of Oral Squamous Cell Carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Efficacy of Carbon Dioxide Paste in Alleviating Pain in Patients After Neck Dissection: Protocol for a Double-Blinded, Randomized Controlled Trial2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exploratory clinical trial to evaluate the efficacy and safety of carbon dioxide paste in healthy people2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Local application of a transcutaneous carbon dioxide paste prevents excessive scarring and promotes muscle regeneration in a bupivacaine‐induced rat model of muscle injury2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Local Application of Transcutaneous Carbon Dioxide Paste Decreases Inflammation and Accelerates Wound Healing2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Transcutaneous Carbon Dioxide Decreases Immunosuppressive Factors in Squamous Cell Carcinoma In Vivo2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Induced Pluripotent Stem Cell-related Genes Correlate With Poor Prognoses of Oral Squamous Cell Carcinoma.2019

Author(s)

Journal Title

DOI

Takeda Daisuke 武田大介