Ikegami Kuniko 池上久仁子

Researcher Number	80779116
Affiliation (Current)	2025: 関西医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2016 – 2023: 大阪大学, 歯学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontology
Keywords	Principal Investigator 老化 / 歯周病 / 細胞老化 / 歯根膜細胞 / CXCR4/SDF-1 / microRNA / 歯根膜 / 鉄 / Ferritin / 幹細胞 … More / micro RNA-34a / ステムセルエイジング / SATB2 / miR-34a / 歯学 Less

CXCR4/SDF-1 axis ameliorates the impaired wound healing and tissue regeneration in aged periodontal tissuePrincipal Investigator
- Principal Investigator
  
  池上久仁子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Physiological and pathophysiological roles of ferritin for cellular senescence in periodontal tissuePrincipal Investigator
- Principal Investigator
  
  Ikegami Kuniko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Analysis of stem-cell aging by targeting miR-34a-SATB2 axisPrincipal Investigator
- Principal Investigator
  
  Ikegami Kuniko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Analysis of micro RNA-34a in senescent periodontal ligament cells.Principal Investigator
- Principal Investigator
  
  Ikegami Kuniko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontology
- Research Institution
  Osaka University

All 2023 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue2023
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Tomomi Nakamura, Koki Hashimoto, Jirouta Kitagaki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Journal Title
  
  Aging
  
  Volume: 15(5) Pages: 1279-1305
- DOI
  10.18632/aging.204569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09963, KAKENHI-PROJECT-22K09979
[Journal Article] Autophagy facilitates type I collagen synthesis in periodontal ligament cells2021
- Author(s)
  Nakamura Tomomi、Yamashita Motozo、Ikegami Kuniko、Suzuki Mio、Yanagita Manabu、Kitagaki Jirouta、Kitamura Masahiro、Murakami Shinya
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41598-020-80275-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21674, KAKENHI-PROJECT-20K18532, KAKENHI-PROJECT-20K18534
[Journal Article] Long-term exposure to cigarette smoke influences characteristics in human gingival fibroblasts2021
- Author(s)
  Mari Tatsumi, Manabu Yanagita, Motozo Yamashita, Shiori Hasegawa, Kuniko Ikegami, Masahiro Kitamura, Shinya Murakami
- Journal Title
  
  J Periodontal Res
  
  Volume: 56(5) Issue: 5 Pages: 951-963
- DOI
  10.1111/jre.12891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21674, KAKENHI-PROJECT-20K18534
[Journal Article] Relative Contribution of Genetic and Environmental Factors to Periodontitis in Elderly Twins2020
- Author(s)
  池上久仁子, 山下元三, 三木康史, 久留島悠子, 高阪貴之, 鈴木美麻, 榎木香織, 松田謙一, 北村正博, 池邉一典, 大阪ツインリサーチグループ, 村上伸也
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 63 Issue: 3 Pages: 236-244
- DOI
  10.11471/shikahozon.63.236
- NAID
  130007871260
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18534
[Journal Article] Clinical Outcome of Periodontal Tissue Regeneration Therapy by Administration of Basic Fibroblast Growth Factor (FGF-2)2020
- Author(s)
  沢田啓吾北村正博長谷川詩織森本千晶平井麻絵今井昂川嵜公輔橋本康樹麻生桃子辻井翔一野田亜利紗花田滉輔政近健司藤田翔子鈴木美麻八木寛子池上久仁子山本智美森健太中村友美小笹匡雄北垣次郎太岩山智明柏木陽一郎藤原千春三木康史竹立匡秀山下元三野崎剛徳村上伸也
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 63 Issue: 3 Pages: 219-227
- DOI
  10.11471/shikahozon.63.219
- NAID
  130007871208
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18534, KAKENHI-PROJECT-18H02982
[Presentation] 早老症Werner症候群患者の歯周病治療2023
- Author(s)
  池上久仁子、山下元三、川口美紅、吉田悠作、板橋光輝、我妻奈都子、北村正博、村上伸也
- Organizer
  第66回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09963
[Presentation] NAD+依存性のミトコンドリアの異常が老化歯根膜における酸化ストレスに及ぼす影響2021
- Author(s)
  橋本康樹，山下元三，池上久仁子，中村友美，西川有彩，森川竜也，北村正博，村上伸也
- Organizer
  第64回秋季日本歯周病学会総会
- Data Source
  KAKENHI-PROJECT-20K18534
[Presentation] 特定臨床研究：歯周炎を対象とした歯周組織再生剤(REGROTH)と人工骨(Cytrans Granules)の併用療法の安全性及び有効性の評価2021
- Author(s)
  北村正博、山下元三、三木康史、池上久仁子、竹立匡秀、柏木陽一郎、野崎剛徳、増田聖、石原容子、山中克之、熊谷知弘、村上伸也
- Organizer
  第64回秋季日本歯周病学会総会
- Data Source
  KAKENHI-PROJECT-20K18534
[Presentation] 高齢者双生児研究に基づく歯周病病態に関連する遺伝・環境要因の解析2020
- Author(s)
  池上久仁子、山下元三、三木康史、鈴木美麻、西川有彩、橋本康樹、森川竜也、竹下登、池邉一典、北村正博、村上伸也
- Organizer
  第63回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-20K18534
[Presentation] 大阪大学歯学部附属病院における塩基性線維芽細胞増殖因子（FGF-2）製剤を用いた歯周組織再生療法の臨床成績2020
- Author(s)
  池上久仁子　沢田啓吾　長谷川詩織　三木康史　竹立匡秀　山下元三　野崎剛徳　北村正博　村上伸也
- Organizer
  特定非営利活動法人　日本臨床歯周病学会第８回JACP関西支部・大学合同研修会
- Data Source
  KAKENHI-PROJECT-20K18534
[Presentation] Genetic and Environmental Factors on Periodontitis in Elderly Twins.2020
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Koji Miki, Arisa Nishikawa, Kouki Hashimoto, Tatsuya Morikawa, Noboru Takeshita, Kazunori Ikebe, Masahiro Kitamura and Shinya Murakami.
- Organizer
  第106回アメリカ歯周病学会共催日本歯周学会・日本臨床歯周病学会2020年大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18534
[Presentation] 老化ヒト歯根膜細胞における活性酸素産生に及ぼすマイトファジーの役割2019
- Author(s)
  鈴木美麻，山下元三，池上久仁子，中村友美，西川有彩，橋本康樹，北村正博，村上伸也
- Organizer
  2019年度日本歯科保存学会春季学術大会（第150回）
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] 老化歯根膜細胞におけるマイトファジーの機能解析2019
- Author(s)
  山下元三、鈴木美麻、池上久仁子、西川有梨沙、橋本康樹、柳田学、北村正博、村上伸也
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] タバコ煙の長期曝露が歯肉線維芽細胞の細胞機能に及ぼす影響2019
- Author(s)
  辰己真理，柳田学，長谷川詩織，鈴木美麻，池上久仁子，山下元三，北村正博，村上伸也
- Organizer
  2019年度日本歯科保存学会春季学術大会（第150回）
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] MiR-34a Regutates Stem Cell Aging in Periodontal ligament Stem Cells.2019
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Kouki Hashimoto, Tomomi Nakamura, Koji Miki, Manabu Yanagita, Masahiro Kitamura and Shinya Murakami.
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] Analysis of Mitophagy in Senescent HPDL Cell.2019
- Author(s)
  Motozo Yamashita, Mio Suzuki, Kuniko Ikegami, Tomomi Nakamura, Arisa Nishikawa, Kouki Hashimoto, Tatsuya Morikawa, Koji Miki, Manabu Yanagita, Masahiro Kitamura and Shinya Murakami.
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] Senescence-associated miR-34a accelerates periodontal stem-cell aging by targeting SATB22018
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Arisa Nishikawa, Tomomi Nakamura, Koji Miki, Jirouta Kitagaki, Manabu Yanagita, Masahiro Kitamura and Shinya Murakami
- Organizer
  American Academy of Periodontology (AAP) 104th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] Optical dissection of the mitophagy dynamics in HPDL cells.2018
- Author(s)
  Motozo Yamashita, Mio Suzuki, Kuniko Ikegami, Tomomi Nakamura, Arisa Nishikawa, Koji Miki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Organizer
  American Academy of Periodontology (AAP) 104th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] Dissection of the mitophagy dynamics in HPDL cells by fluorescent probe.2018
- Author(s)
  Mio Suzuki, Motozo Yamashita, Kuniko Ikegami, Tomomi Nakamura, Arisa Nishikawa, Kouki Hashimoto, Koji Miki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Organizer
  第66回国際歯科研究学会日本部会総会・学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] Effects of long-term exposure of cigarette smoke on gingival fibroblasts2018
- Author(s)
  Mari Tatsumi, Manabu Yanagita, Shiori Hasegawa, Mio Suzuki, Kuniko Ikegami, Motozo Yamashita, Masahiro Kitamura, Shinya Murakami
- Organizer
  第66回国際歯科研究学会日本部会総会・学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] Senescence-associated miR-34a suppress osteoblastic differentiation in periodontal stem cell.2018
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Arisa Nishikawa, Tomomi Nakamura, Koji Miki, Manabu Yanagita, Masahiro Kitamura and Shinya Murakami
- Organizer
  第66回国際歯科研究学会日本部会総会・学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17064
[Presentation] ヒト老化歯根膜細胞におけるmicroRNA-34a -SATB2を介した硬組織形成制御2017
- Author(s)
  池上久仁子、山下元三、鈴木美麻、三木康史、北垣次郎太、柳田学、北村正博、村上伸也
- Organizer
  日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] 歯周組織の老化性炎症におけるmicroRNA-34aの役割2017
- Author(s)
  池上久仁子、山下元三、鈴木美麻、山本智美、沢田啓吾、森健太、粟田敏仁、大原廣之、柏木陽一郎、小笹匡雄、竹立匡秀、北垣次郎太、柳田学、野崎剛徳、山田聡、北村正博、村上伸也
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] 歯周組織の老化性炎症におけるmicroRNA-34aの役割2017
- Author(s)
  池上久仁子、山下元三、鈴木美麻、山本智美、沢田啓吾、森健太、粟田敏仁、大原廣之、柏木陽一郎、小笹匡雄、竹立匡秀、北垣次郎太、柳田学、野崎剛徳、山田聡、北村正博、村上伸也
- Organizer
  第16回　日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] 歯根膜の老化性炎症における細胞老化の役割2016
- Author(s)
  池上久仁子、山下元三、鈴木美麻、柳田学、野崎剛徳、山田聡、北村正博、村上伸也
- Organizer
  第59回秋季日本歯周病学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] microRNA-34a によるヒト歯根膜細胞の老化制御2016
- Author(s)
  山下元三、池上久仁子、鈴木美麻、柳田学、山田聡、北村正博、村上伸也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] 歯周病に関与する遺伝因子と環境因子の検討－双生児研究からの解析－2016
- Author(s)
  三木康史、山下元三、池上久仁子、鈴木美麻、久留島悠子、池邉一典、北村正博、前田芳信、村上伸也
- Organizer
  第23回　日本歯科医学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16H06962

1. YAMASHITA MOTOZO (90524984)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. MURAKAMI SHINYA (70239490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 柏木陽一郎 (20598396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ikegami Kuniko 池上 久仁子

Research Projects

Research Products

Co-Researchers

CXCR4/SDF-1 axis ameliorates the impaired wound healing and tissue regeneration in aged periodontal tissuePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological and pathophysiological roles of ferritin for cellular senescence in periodontal tissuePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of stem-cell aging by targeting miR-34a-SATB2 axisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of micro RNA-34a in senescent periodontal ligament cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autophagy facilitates type I collagen synthesis in periodontal ligament cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term exposure to cigarette smoke influences characteristics in human gingival fibroblasts2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relative Contribution of Genetic and Environmental Factors to Periodontitis in Elderly Twins2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Clinical Outcome of Periodontal Tissue Regeneration Therapy by Administration of Basic Fibroblast Growth Factor (FGF-2)2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] 早老症Werner症候群患者の歯周病治療2023

Author(s)

Organizer

Data Source

[Presentation] NAD+依存性のミトコンドリアの異常が老化歯根膜における酸化ストレスに及ぼす影響2021

Author(s)

Organizer

Data Source

[Presentation] 特定臨床研究：歯周炎を対象とした歯周組織再生剤(REGROTH)と人工骨(Cytrans Granules)の併用療法の安全性及び有効性の評価2021

Author(s)

Organizer

Data Source

[Presentation] 高齢者双生児研究に基づく歯周病病態に関連する遺伝・環境要因の解析2020

Author(s)

Organizer

Data Source

[Presentation] 大阪大学歯学部附属病院における塩基性線維芽細胞増殖因子（FGF-2）製剤を用いた歯周組織再生療法の臨床成績2020

Author(s)

Organizer

Data Source

[Presentation] Genetic and Environmental Factors on Periodontitis in Elderly Twins.2020

Ikegami Kuniko 池上久仁子