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Chang Song Ho  張 成虎

ORCIDConnect your ORCID iD *help
Researcher Number 80780551
Other IDs
Affiliation (based on the past Project Information) *help 2019: 東京大学, 医学部附属病院, 助教
2019: 東京大学, 医学部附属病院, 特任臨床医
2018: 東京大学, 医学部附属病院, 登録研究員
2017: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field
Principal Investigator
Orthopaedic surgery
Except Principal Investigator
Orthopaedic surgery
Keywords
Principal Investigator
メカニカルストレス / VEGFR2 / NF-kBシグナル / 力学的負荷 / 軟骨代謝 / 力学的ストレス / 変形性関節症
Except Principal Investigator
骨・軟骨代謝学 / 変形性関節症 / 骨軟骨代謝学 … More / 関節最表層 / 整形外科学 / メカニカルストレス / 滑膜組織 / 軟骨前駆細胞 / メカノセンサー / Fluid Flow Shear Stress / Lubricin / 軟骨分化 / メカノトランスデューサー / 関節軟骨表層 / 軟骨細胞 / Trpv2 / メカノセンシティブイオンチャネル / 変形性膝関節症 / 医療・福祉 / laser micro dissection / FACS / RNAシークエンス / LMD / 腱再生 / 腱 Less
  • Research Projects

    (4 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (14 People)
  •  Elucidation of tendon regeneration mechanism using achilles tendon resection model.

    • Principal Investigator
      Uehara Kosuke
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Mechano-sensor TRPV2 is involved in lubricin induction and suppression of ectopic endochondral ossification in articular joints

    • Principal Investigator
      Kawaguchi Kohei
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Investigation of new osteoarthritis treatment targeting GREM1 induced by excessive mechanical stress loading.Principal Investigator

    • Principal Investigator
      Chang Song Ho
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Regulation of Articular Chondrocyte Differentiation

    • Principal Investigator
      Saito Taku
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo

All 2020 2019 2017

All Journal Article Presentation

  • [Journal Article] Association between fall history and performance-based physical function and postural sway in patients with rheumatoid arthritis.2020

    • Author(s)
      Kawabata K, Matsumoto T, Kasai T, Chang SH, Hirose J, Tanaka S.
    • Journal Title

      Mod Rheumatol

      Volume: 1-7 Issue: 2 Pages: 373-379

    • DOI

      10.1080/14397595.2020.1731134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10956
  • [Journal Article] Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling2020

    • Author(s)
      Okada Keita、Mori Daisuke、Makii Yuma、Nakamoto Hideki、Murahashi Yasutaka、Yano Fumiko、Chang Song Ho、Taniguchi Yuki、Kobayashi Hiroshi、Semba Hiroaki、Takeda Norihiko、Piao Wen、Hanaoka Kenjiro、Nagano Tetsuo、Tanaka Sakae、Saito Taku
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 5425-5425

    • DOI

      10.1038/s41598-020-62463-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-19H05414, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-18H02360, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-18K09017, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-20K09405
  • [Journal Article] Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-52019

    • Author(s)
      Miyauchi Aya、Kim-Kaneyama Joo-ri、Lei Xiao-Feng、Chang Song Ho、Saito Taku、Haraguchi Shogo、Miyazaki Takuro、Miyazaki Akira
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 15770-15770

    • DOI

      10.1038/s41598-019-52301-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K08590, KAKENHI-PROJECT-19K09033, KAKENHI-PROJECT-19H03110, KAKENHI-PROJECT-17K09869, KAKENHI-PROJECT-17K10713, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
  • [Journal Article] Excessive mechanical loading promotes osteoarthritis through the gremlin-1?NF-κB pathway2019

    • Author(s)
      Chang Song Ho、Mori Daisuke、Kobayashi Hiroshi、Mori Yoshifumi、Nakamoto Hideki、Okada Keita、Taniguchi Yuki、Sugita Shurei、Yano Fumiko、Chung Ung-il、Kim-Kaneyama Joo-ri、Yanagita Motoko、Economides Aris、Canalis Ernesto、Chen Di、Tanaka Sakae、Saito Taku
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 1442-1442

    • DOI

      10.1038/s41467-019-09491-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17K16675, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-17K19715, KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K22620, KAKENHI-PUBLICLY-18H04673, KAKENHI-PROJECT-17H04187, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955
  • [Journal Article] Sandwich-type PLLA-nanosheets loaded with BMP-2 induce bone regeneration in critical-sized mouse calvarial defects2017

    • Author(s)
      Huang KC, Yano F, Murahashi Y, Takano S, Kitaura Y, Chang SH, Soma K, Ueng SWN, Tanaka S, Ishihara K, Okamura Y, Moro T, Saito T
    • Journal Title

      Acta Biomater

      Volume: 59 Pages: 12-20

    • DOI

      10.1016/j.actbio.2017.06.041

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462
  • [Journal Article] A Mouse Intervertebral Disc Degeneration Model by Surgically-Induced Instability2017

    • Author(s)
      Oichi T, Taniguchi Y, Soma K, Chang SH, Yano F, Tanaka S, Saito T
    • Journal Title

      Spine

      Volume: ― Issue: 10 Pages: 1-1

    • DOI

      10.1097/brs.0000000000002427

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10811, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955
  • [Journal Article] Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63.2017

    • Author(s)
      Taniguchi Y, Kawata M, Chang SH, Mori D, Okada K, Kobayashi H, Sugita S, Hosaka Y, Inui H, Taketomi S, Yano F, Ikeda T, Akiyama H, Mills AA, Chung UI, Tanaka S, Kawaguchi H, and Saito T*
    • Journal Title

      Arthritis Rheumatol.

      Volume: 69 Issue: 3 Pages: 598-609

    • DOI

      10.1002/art.39976

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H04311, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-25713052
  • [Presentation] 過剰なメカニカルストレスは Gremlin-1-NF-kB シグナルを介して変形性関節症を引き起こす2020

    • Author(s)
      張成虎
    • Organizer
      第33回 日本軟骨代謝学会
    • Data Source
      KAKENHI-PROJECT-17K16675
  • [Presentation] GREMLIN1 INDUCED BY EXCESSIVE MECHANICAL STRESS LOADING ENHANCES CARTILAGE DEGRADATION.2019

    • Author(s)
      張成虎
    • Organizer
      The 7th Seoul Symposium on Bone Health,Seoul,Korea 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16675
  • 1.  Saito Taku (30456107)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  Uehara Kosuke (20599063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Kawaguchi Kohei (40794227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  森崎 裕 (30508099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  矢野 文子 (80529040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  武冨 修治 (70570018)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  小林 寛 (20407951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  OKA Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  金山 朱里
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  川口 浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  鄭 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  乾 洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  岡田 慶太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  森 大典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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