Hojo Hironori 北條宏徳

Researcher Number	80788422
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 准教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 東京大学, 大学院医学系研究科(医学部), 准教授 2017 – 2018: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 57:Oral science and related fields / Basic Section 90110:Biomedical engineering-related / Basic Section 57060:Surgical dentistry-related / Surgical dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 57:Oral science and related fields / Surgical dentistry / Basic Section 57020:Oral pathobiological science-related / Basic Section 57070:Developmental dentistry-related … More / Broad Section I / Basic Section 37030:Chemical biology-related / Biomedical engineering/Biomaterial science and engineering / Oral Science and related fields Less
Keywords	Principal Investigator 一細胞解析 / １細胞解析 / エピゲノム / 骨発生 / 転写制御 / 骨形成 / 骨芽細胞 / エンハンサー / 一細胞CRISPRスクリーニング / SNP … More / CRISPRスクリーニング / GWAS / CRISPR / 細胞系譜実験 / 遺伝子発現制御 / 細胞系譜 / 遺伝子発現機構 / 骨修復 / シグナルネットワーク / 骨再生 / バイオインフォマティクス / 発現制御 / 発生・分化 / 転写因子 / Runx2 / 一細胞RNA-seq / エンハンサースクリーニング / ゲノム編集 … More Except Principal Investigator 変形性関節症 / 一細胞解析 / 骨 / 骨再生 / バイオマテリアル / エピゲノム解析 / 骨代謝 / 唾液腺発生 / 遺伝子発現変動 / ChIP-seq / Foxc1 / 滑膜 / 関節滑膜組織 / 顎関節症 / 関節軟骨 / ルブリシン / エンハンサー / インディアンヘッジホッグ / 骨格系 / 歯科矯正学 / 次世代シーケンサー / 臍帯組織 / 口唇口蓋裂 / 関節炎 / 免疫細胞 / 運動器 / 骨免疫 / 関節リウマチ / シングルセル解析 / 運動器恒常性維持 / 骨欠損 / 線維化 / 組織リモデリング / ヘリオキサンチン類縁体 / 多能性幹細胞 / へリオキサンチン類縁体 / 軟骨 / ミトコンドリア / 骨軟骨分化 / ケミカルバイオロジー / ゲノム編集 / ヒト多能性幹細胞 / 骨誘導 / hPSCs / １細胞解析 / 幹細胞 / 幹細胞ニッシ / open chromatin analysis / GREAT解析 / 造血-間葉相互作用 / 骨髄間葉系幹細胞 / ATAC-seq / RNA-seq / single cell RNA-seq / 幹細胞niche / 多能性前駆細胞 / 骨髄 / ＥＳ細胞 / 破骨細胞 / 骨芽細胞 / ES細胞 / 統合インターフェース / 骨軟骨 / シグナル / 人工骨 / ハイドロゲル / 骨軟骨生物学 / 再生医工学 / エピゲノム / 再生医学 / in vivoイメージング / ゲノムワイド解析 / バイオインフォマティクス / 細胞遊走 Less

ヒト内軟骨性骨化を模倣する骨オルガノイド法の開発と骨系統疾患の研究基盤の構築Principal Investigator
- Principal Investigator
  
  北條宏徳
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Establishment of an integrated locomotive science including spatiotemporal dynamics of bone-articular cells
- Principal Investigator
  
  田中栄
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  The University of Tokyo
The mechanism of joint homeostasis in the coupling of articular cartilage and synovium
- Principal Investigator
  
  矢野文子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Showa University
Foxc1によるFgfr2発現機構の解明
- Principal Investigator
  
  行森茜
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Showa University
Evaluation of properties by epigenome analysis for human umbilical cord-derived stromal cells and research for bone regenerative medicine
- Principal Investigator
  
  金澤三四朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
Sp7-Dlx相互作用の顎顔面骨再生における機能の解明と歯科矯正治療への応用
- Principal Investigator
  
  大久保和美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  The University of Tokyo
ヒト骨発生機構の理解に基づく組織再生研究基盤の構築
- Principal Investigator
  
  鄭雄一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Prohibitinの軟骨分化機能解析とその知見を用いた変形性関節症薬の探索
- Principal Investigator
  
  下畑宣行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Keio University
  Ritsumeikan University
Development of a functional GWAS-SNP detection method using single-cell CRISPR screening methodPrincipal Investigator
- Principal Investigator
  
  Hojo Hironori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  The University of Tokyo
Investigation of the mechanism of actions of the helioxanthin-derivative and its application as a multi-kinase inhibitor
- Principal Investigator
  
  Ohba Shinsuke
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
  Nagasaki University
Development of bone regeneration methods based on understanding of tissue remodeling
- Principal Investigator
  
  Tei Yuichi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Comprehensive understanding of the enhancer cluster that regulates the expression of Indian hedgehog in the skeletal system
- Principal Investigator
  
  大庭伸介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
  Nagasaki University
Comparative Analysis of Epigenomic Dynamics in Bone Development and Repair and its Application to Bone RegenerationPrincipal Investigator
- Principal Investigator
  
  Hojo Hironori
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
In vitro modeling of human bone metabolism using pluripotent stem cell-derived bone organoids
- Principal Investigator
  
  OHBA Shinsuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nagasaki University
  The University of Tokyo
Development of functional enhancer screening system by integrating genome editing technology with single-cell RNA-seqPrincipal Investigator
- Principal Investigator
  
  Hojo Hironori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  The University of Tokyo
Elucidation of stem cell signal using genome structure as an index and application to bone regenerative medicine
- Principal Investigator
  
  Hoshi Kazuto
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
Identification of regulatory factors contributing to migration or recruitment of osteoblast progenitors by genome-wide approach and the application for bone repair
- Principal Investigator
  
  Takato Tsuyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Oral Science and related fields
- Research Institution
  The University of Tokyo
Fundamental study of bone regeneration with site-specific epigenome editing
- Principal Investigator
  
  Ohba Shinsuke
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
  The University of Tokyo
Understanding of Runx2-mediated hierarichical gene regulatory network in bone formation and application of the network for bone regenerationPrincipal Investigator
- Principal Investigator
  
  Hojo Hironori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Identification of osteoclast-supporting cells and the investigation of the in vivo functions of the cells using mouse ES cells
- Principal Investigator
  
  Okayasu Mari
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Development of 4-dimensional scaffold system that integrates signaling factors and 3-dimensional structural biomaterials
- Principal Investigator
  
  Tei Yuichi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book Patent

[Book] 先進医療NAVIGATOR 再生医療・細胞医療の研究と産業化の最前線第２章 14 骨再生医療等の現状と課題2019
- Author(s)
  北條宏徳，鄭　裕一，大庭伸介
- Total Pages
  93
- Publisher
  日本医学出版（先進医療フォーラム編）
- ISBN
  9784865770308
- Data Source
  KAKENHI-PROJECT-18H02998
[Journal Article] Injectable phase-separated tetra-armed poly(ethylene glycol) hydrogel scaffold allows sustained release of growth factors to enhance the repair of critical bone defects2024
- Author(s)
  Nepal Shant、Si Jinyan、Ishikawa Shohei、Nishikawa Masaki、Sakai Yasuyuki、Akimoto Aya M.、Okada Hiroyuki、Ohba Shinsuke、Chung Ung-il、Sakai Takamasa、Hojo Hironori
- Journal Title
  
  Regenerative Therapy
  
  Volume: 25 Pages: 24-34
- DOI
  10.1016/j.reth.2023.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885
[Journal Article] Percolation-induced gel-gel phase separation in a dilute polymer network2023
- Author(s)
  Ishikawa Shohei、Iwanaga Yasuhide、Uneyama Takashi、Li Xiang、Hojo Hironori、Fujinaga Ikuo、Katashima Takuya、Saito Taku、Okada Yasushi、Chung Ung-il、Sakumichi Naoyuki、Sakai Takamasa
- Journal Title
  
  Nature Materials
  
  Volume: 22 Issue: 12 Pages: 1564-1570
- DOI
  10.1038/s41563-023-01712-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18325, KAKENHI-PROJECT-21K09243, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21H04688, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K22458, KAKENHI-PROJECT-23K24060, KAKENHI-PROJECT-23K27718
[Journal Article] Modeling of intramembranous ossification using human pluripotent stem cell-derived paraxial mesoderm derivatives.2023
- Author(s)
  Ikeda Y., Tani S., Moriishi T., Kuroda A., Matsuo Y., Saeki N., Inui-Yamamoto C., Abe M., Maeda T., Rowe DW., Chung UI., Hojo H., Matsushita Y., Sawase T., Ohba S.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 24 Pages: 536-546
- DOI
  10.1016/j.reth.2023.09.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06295, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K21494
[Journal Article] Runt-related Transcription Factors and Gene Regulatory Mechanisms in Skeletal Development and Diseases2023
- Author(s)
  Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  Current Osteoporosis Reports
  
  Volume: 21 Issue: 5 Pages: 485-492
- DOI
  10.1007/s11914-023-00808-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05318, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K21494
[Journal Article] Stem cell-based modeling and single-cell multiomics reveal gene-regulatory mechanisms underlying human skeletal development2023
- Author(s)
  Tani Shoichiro, Okada Hiroyuki, Onodera Shoko, Chijimatsu Ryota, Seki Masahide, Suzuki Yutaka, Xin Xiaonan, Rowe David W., Saito Taku, Tanaka Sakae, Chung Ung-il, Ohba Shinsuke, Hojo Hironori
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 4 Pages: 112276-112276
- DOI
  10.1016/j.celrep.2023.112276
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05318, KAKENHI-PROJECT-22K08773, KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-21J12970, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K21494, KAKENHI-PROJECT-23K27718
[Journal Article] Conditional inactivation of the L‐type amino acid transporter LAT1 in chondrocytes models idiopathic scoliosis in mice2022
- Author(s)
  Iwahashi Sayuki、Lyu Jiajun、Tokumura Kazuya、Osumi Ryoma、Hiraiwa Manami、Kubo Takuya、Horie Tetsuhiro、Demura Satoru、Kawakami Noriaki、Saito Taku、Park Gyujin、Fukasawa Kazuya、Iezaki Takashi、Suzuki Akane、Tomizawa Akane、Ochi Hiroki、Hojo Hironori、Ohba Shinsuke、Hinoi Eiichi
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 237 Issue: 11 Pages: 4292-4302
- DOI
  10.1002/jcp.30883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15350, KAKENHI-PROJECT-20H03885
[Journal Article] A neomorphic variant in SP7 alters sequence specificity and causes a high-turnover bone disorder2022
- Author(s)
  Lui Julian C.、Raimann Adalbert、Hojo Hironori、Dong Lijin、Roschger Paul、Kikani Bijal、Wintergerst Uwe、Fratzl-Zelman Nadja、Jee Youn Hee、Haeusler Gabriele、Baron Jeffrey
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 700-700
- DOI
  10.1038/s41467-022-28318-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883
[Journal Article] Sp7 Action in the Skeleton: Its Mode of Action, Functions, and Relevance to Skeletal Diseases2022
- Author(s)
  Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 10 Pages: 5647-5647
- DOI
  10.3390/ijms23105647
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K19611, KAKENHI-PROJECT-23K21494
[Journal Article] Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development2022
- Author(s)
  Nagata K, Hojo H, Chang SH, Okada H, Chijimatsu R, Omata Y, Mori D, Makii Y, Kawata M, Kaneko T, Iwanaga Y, Nakamoto H, Maenohara Y, Tachibana N, Ishikura H, Higuchi J, Taniguchi Y, Ohba S, Chung Ul, Tanaka S, Saito T
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 6187-6204
- DOI
  10.1038/s41467-022-33744-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08773, KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-22KK0272, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-21K16703, KAKENHI-PROJECT-21K20942
[Journal Article] Single-cell RNA sequencing unravels heterogeneity of skeletal progenitors and cell-cell interactions underlying the bone repair process2022
- Author(s)
  Nakayama Mika、Okada Hiroyuki、Seki Masahide、Suzuki Yutaka、Chung Ung-il、Ohba Shinsuke、Hojo Hironori
- Journal Title
  
  Regenerative Therapy
  
  Volume: 21 Pages: 9-18
- DOI
  10.1016/j.reth.2022.05.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-22KK0272, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-23K21494
[Journal Article] intra-single cell sequencing (iSCseq) spotlights transcriptomic and epigenetic heterogeneity inside multinucleated osteoclast2022
- Author(s)
  Okada Hiroyuki、Terui Yuta、Omata Yasunori、Seki Masahide、Tani Shoichiro、Miyahara Junya、Makabe Kenta、Terashima Asuka、Kanazawa Sanshiro、Hosonuma Masahiro、Yano Fumiko、Kajiya Hiroshi、Saito Taku、Suzuki Yutaka、Okabe Koji、Baron Roland、Tanaka Sakae、Chung Ung-il、Hojo Hironori
- Journal Title
  
  bioRxiv
  
  Volume: 0 Pages: 0-0
- DOI
  10.1101/2022.09.05.506360
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22KK0272, KAKENHI-PROJECT-21K16703, KAKENHI-PROJECT-23K15736
[Journal Article] Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages2022
- Author(s)
  Hojo Hironori, Saito Taku, He Xinjun, Guo Qiuyu, Onodera Shoko, Azuma Toshifumi, Koebis Michinori, Nakao Kazuki, Aiba Atsu, Seki Masahide, Suzuki Yutaka, Okada Hiroyuki, Tanaka Sakae, Chung Ung-il, McMahon Andrew P., Ohba Shinsuke
- Journal Title
  
  Cell Reports
  
  Volume: 40 Issue: 10 Pages: 111315-111315
- DOI
  10.1016/j.celrep.2022.111315
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05318, KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-22KK0272, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-23K21494, KAKENHI-PROJECT-21H03146
[Journal Article] Orally administrable peptides derived from egg yolk promote skeletal repair and ameliorate degenerative skeletal disorders in mouse models2022
- Author(s)
  Kitaura Yoshiaki、Nakamura Utano、Awada Chihiro、Yamaguchi Motonori、Kim Mujo、Ikeda Yuki、Matsuo Yuki、Moriishi Takeshi、Sawase Takashi、Chung Ung-il、Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  Regenerative Therapy
  
  Volume: 21 Pages: 584-595
- DOI
  10.1016/j.reth.2022.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19611, KAKENHI-PROJECT-21K19883
[Journal Article] Involvement of activator protein-1 family members in β-catenin and p300 association on the genome of PANC-1 cells2022
- Author(s)
  Doi Tomomitsu、Hojo Hironori、Ohba Shinsuke、Obayashi Kunie、Endo Motoyoshi、Ishizaki Toshimasa、Katoh Akira、Kouji Hiroyuki
- Journal Title
  
  Heliyon
  
  Volume: 8 Issue: 2 Pages: e08890-e08890
- DOI
  10.1016/j.heliyon.2022.e08890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K07972, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19611, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-20K08530
[Journal Article] Mesenchymal stromal cells in the bone marrow niche consist of multi-populations with distinct transcriptional and epigenetic properties2021
- Author(s)
  Kanazawa Sanshiro、Okada Hiroyuki、Hojo Hironori、Ohba Shinsuke、Iwata Junichi、Komura Makoto、Hikita Atsuhiko、Hoshi Kazuto
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 15811-15811
- DOI
  10.1038/s41598-021-94186-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22973, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-21K16703, KAKENHI-PROJECT-23K21494
[Journal Article] Induction and expansion of human PRRX1+ limb-bud-like mesenchymal cells from pluripotent stem cells2021
- Author(s)
  Yamada Daisuke、Nakamura Masahiro、Takao Tomoka、Takihira Shota、Yoshida Aki、Kawai Shunsuke、Miura Akihiro、Ming Lu、Yoshitomi Hiroyuki、Gozu Mai、Okamoto Kumi、Hojo Hironori、Kusaka Naoyuki、Iwai Ryosuke、Nakata Eiji、Ozaki Toshifumi、Toguchida Junya、Takarada Takeshi
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 5 Issue: 8 Pages: 926-940
- DOI
  10.1038/s41551-021-00778-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-23K21368, KAKENHI-PROJECT-22K09401
[Journal Article] Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin2021
- Author(s)
  Wang JS, Kamath T, Mazur CM, Mirzamohammadi F, Rotter D, Hojo H, Castro CD, Tokavanich N, Patel R, Govea N, Enishi T, Wu Y, da Silva Martins J, Bruce M, Brooks DJ, Bouxsein ML, Tokarz D, Lin CP, Abdul A, Macosko EZ, Fiscaletti M, Munns CF, Ryder P, Kost-Alimova M, Byrne P, Cimini B, Fujiwara M, Kronenberg HM, Wein MN.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 6271-6271
- DOI
  10.1038/s41467-021-26571-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21K19883
[Journal Article] ChIP-Seq Assays from Mammalian Cartilage and Chondrocytes.2021
- Author(s)
  Hojo H, Ohba S et al.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2245 Pages: 167-178
- DOI
  10.1007/978-1-0716-1119-7_12
- ISBN
  9781071611180, 9781071611197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02998
[Journal Article] The Progress of Stem Cell Technology for Skeletal Regeneration2021
- Author(s)
  Tani Shoichiro、Okada Hiroyuki、Chung Ung-il、Ohba Shinsuke、Hojo Hironori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1404-1404
- DOI
  10.3390/ijms22031404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-20K22973, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-21K16703
[Journal Article] Stepwise strategy for generating osteoblasts from human pluripotent stem cells under fully defined xeno-free conditions with small-molecule inducers2020
- Author(s)
  Zujur Denise、Kanke Kosuke、Onodera Shoko、Tani Shoichiro、Lai Jenny、Azuma Toshifumi、Xin Xiaonan、Lichtler Alexander C.、Rowe David W.、Saito Taku、Tanaka Sakae、Masaki Hideki、Nakauchi Hiromitsu、Chung Ung-il、Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  Regenerative Therapy
  
  Volume: 14 Pages: 19-31
- DOI
  10.1016/j.reth.2019.12.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H03007, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K11898, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19H03833, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Hedgehog Activation Regulates Human Osteoblastogenesis2020
- Author(s)
  Onodera Shoko、Saito Akiko、Hojo Hironori、Nakamura Takashi、Zujur Denise、Watanabe Katsuhito、Morita Nana、Hasegawa Daigo、Masaki Hideki、Nakauchi Hiromitsu、Nomura Takeshi、Shibahara Takahiko、Yamaguchi Akira、Chung Ung-il、Azuma Toshifumi、Ohba Shinsuke
- Journal Title
  
  Stem Cell Reports
  
  Volume: 15 Issue: 1 Pages: 125-139
- DOI
  10.1016/j.stemcr.2020.05.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-20H03894, KAKENHI-PROJECT-18H03007
[Journal Article] Understanding paraxial mesoderm development and sclerotome specification for skeletal repair2020
- Author(s)
  Tani Shoichiro、Chung Ung-il、Ohba Shinsuke、Hojo Hironori
- Journal Title
  
  Experimental & Molecular Medicine
  
  Volume: 52 Issue: 8 Pages: 1166-1177
- DOI
  10.1038/s12276-020-0482-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885
[Journal Article] Gene regulatory landscape in osteoblast differentiation.2020
- Author(s)
  Hojo H, Ohba S.
- Journal Title
  
  Bone
  
  Volume: Epub 2020 Pages: 115458-115458
- NAID
  120006988169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02998
[Journal Article] Gene regulatory landscape in osteoblast differentiation2020
- Author(s)
  Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  Bone
  
  Volume: 137 Pages: 115458-115458
- DOI
  10.1016/j.bone.2020.115458
- NAID
  120006988169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-20H03885
[Journal Article] Insights into Gene Regulatory Networks in Chondrocytes2019
- Author(s)
  Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 24 Pages: 6324-6324
- DOI
  10.3390/ijms20246324
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998
[Journal Article] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds2019
- Author(s)
  Kawata Manabu、Mori Daisuke、Kanke Kosuke、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Yano Fumiko、Masaki Hideki、Otsu Makoto、Nakauchi Hiromitsu、Tanaka Sakae、Saito Taku
- Journal Title
  
  Stem Cell Reports
  
  Volume: 13 Issue: 3 Pages: 530-544
- DOI
  10.1016/j.stemcr.2019.07.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K19600, KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] ゲノムワイドデータとバイオインフォマティクスに基づく転写制御因子とゲノムDNAの相互作用分析2019
- Author(s)
  大庭伸介, 北條宏徳
- Journal Title
  
  バイオマテリアル－生体材料－
  
  Volume: 37 Pages: 244-251
- Data Source
  KAKENHI-PROJECT-17H04403
[Journal Article] Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone2019
- Author(s)
  Xuan Fengjun、Yano Fumiko、Mori Daisuke、Chijimatsu Ryota、Maenohara Yuji、Nakamoto Hideki、Mori Yoshifumi、Makii Yuma、Oichi Takeshi、Taketo Makoto Mark、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Tanaka Sakae、Saito Taku
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 21 Issue: 1 Pages: 247-247
- DOI
  10.1186/s13075-019-2041-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Generation of orthotopically functional salivary gland from embryonic stem cells2018
- Author(s)
  Tanaka Junichi、Ogawa Miho、Hojo Hironori、Kawashima Yusuke、Mabuchi Yo、Hata Kenji、Nakamura Shiro、Yasuhara Rika、Takamatsu Koki、Irie Tarou、Fukada Toshiyuki、Sakai Takayoshi、Inoue Tomio、Nishimura Riko、Ohara Osamu、Saito Ichiro、Ohba Shinsuke、Tsuji Takashi、Mishima Kenji
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4216-4216
- DOI
  10.1038/s41467-018-06469-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11488, KAKENHI-PROJECT-18K09540, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-17H04011, KAKENHI-PROJECT-17H04373, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-15K06853, KAKENHI-PROJECT-16K11459, KAKENHI-PROJECT-15K15737, KAKENHI-PROJECT-17K19775, KAKENHI-PROJECT-17K17088, KAKENHI-PROJECT-15H02575
[Journal Article] Bone regeneration by human dental pulp stem cells using a helioxanthin derivative and cell-sheet technology.2018
- Author(s)
  Fujii Y, Kawase-Koga Y, Hojo H, Yano F, Sato M, Chung UI, Ohba S, Chikazu D.
- Journal Title
  
  Stem Cell Res Ther
  
  Volume: 9 Issue: 1 Pages: 24-24
- DOI
  10.1186/s13287-018-0783-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K19744, KAKENHI-PROJECT-26221311, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K15536
[Journal Article] Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions2017
- Author(s)
  Zujur D, Kanke K, Lichtler AC, Hojo H, Chung UI, Ohba S
- Journal Title
  
  Science Advanvces
  
  Volume: 3 Issue: 5
- DOI
  10.1126/sciadv.1602875
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-26221311, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-16H06762, KAKENHI-PROJECT-17H05106
[Journal Article] Identification of the gene-regulatory landscape in skeletal development and potential links to skeletal regeneration.2017
- Author(s)
  Hojo H, Chung UI, Ohba S
- Journal Title
  
  Regenerative Therapy
  
  Volume: 6 Pages: 100-107
- DOI
  10.1016/j.reth.2017.04.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19744, KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-15K15732, KAKENHI-PROJECT-17H05106
[Journal Article] Local administration of a hedgehog agonist accelerates fracture7healing in a mouse model.2016
- Author(s)
  Kashiwagi M, Hojo H, Kitaura Y, Maeda Y, Aini H, Takato T, Chung U, Ohba S.
- Journal Title
  
  Biochem Biophys Res Comm
  
  Volume: 479 Issue: 4 Pages: 772-778
- DOI
  10.1016/j.bbrc.2016.09.134
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-26221311, KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-26670859, KAKENHI-PROJECT-15K15732
[Patent] 椎板細胞の製造方法および該椎板細胞の利用2022
- Inventor(s)
  大庭伸介、谷彰一郎、北條宏徳、鄭雄一
- Industrial Property Rights Holder
  大庭伸介、谷彰一郎、北條宏徳、鄭雄一
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-17H04403
[Patent] 椎板細胞の製造方法および該椎板細胞の利用2021
- Inventor(s)
  大庭伸介、谷彰一郎、北條宏徳、鄭雄一
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-041384
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-18K19635
[Patent] 椎板細胞の製造方法および該椎板細胞の利用2021
- Inventor(s)
  大庭伸介、谷彰一郎、北條宏徳、鄭雄一
- Industrial Property Rights Holder
  大庭伸介、谷彰一郎、北條宏徳、鄭雄一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-041384
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-17H04403
[Patent] 再生医療用ゲル材料2020
- Inventor(s)
  酒井崇匡、北條宏徳、谷彰一郎、増井公祐、成田真一
- Industrial Property Rights Holder
  酒井崇匡、北條宏徳、谷彰一郎、増井公祐、成田真一
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] Modeling of skeletal development using human pluripotent stem cells and exploring the gene regulatory networks2023
- Author(s)
  Hironori Hojo
- Organizer
  The Korean Society for Biotechnology and Bioengineering (KSBB)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10261
[Presentation] Injectable phase-separated tetra-armed polyethylene glycol (PEG) hydrogel scaffold allows sustained release of signaling factors to enhance the repair of cranial bone defects2023
- Author(s)
  Shant Nepal, Jinyan Si, Shohei Ishikawa, Hiroyuki Okada, Shinsuke Ohba, Ung-il Chung, Takamasa Sakai, Hironori Hojo
- Organizer
  ASBMR 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Exploring Gene Regulatory Networks (GRNs) in skeletal development using human Pluripotent Stem Cells (PSCs) and future perspective for clinical applications2023
- Author(s)
  Hironori Hojo
- Organizer
  International Congress of Osteoporosis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Injectable phase-separated tetra-armed polyethylene glycol (PEG) hydrogel scaffold allows sustained release of signaling factors to enhance the repair of cranial bone defects2023
- Author(s)
  Shant Nepal, Jinyan Si, Shohei Ishikawa, Hiroyuki Okada, Shinsuke Ohba, Ung-il Chung, Takamasa Sakai, Hironori Hojo
- Organizer
  ASBMR 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19589
[Presentation] Emerging gene regulatory networks in skeletal development in the mouse and human models2023
- Author(s)
  北條　宏徳
- Organizer
  第41回日本骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05318
[Presentation] Human pluripotent stem cell-based systems recapitulating intramembranous ossification.2023
- Author(s)
  Ikeda Y, Tani S, Moriishi T, Kuroda A, Matsuo Y, Inui C, Abe N, Maeda T, Chung UI, Hojo H, Matsushita Y, Sawase T, Ohba S
- Organizer
  International Society for Stem Cell Research 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] Modeling of skeletal development using human pluripotent stem cells and exploring the gene regulatory networks2023
- Author(s)
  Hironori Hojo
- Organizer
  The Korean Society for Biotechnology and Bioengineering (KSBB) 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] 運動器発のサブセルラーシーケンスで細胞生物学の常識に挑む2023
- Author(s)
  岡田　寛之, 照井　悠太, 小俣　康徳, 関　真秀, 谷　彰一郎, 宮原　潤也, 真壁　健太, 寺島　明日香, 金澤　三四朗, 細沼　雅弘, 矢野　文子, 小野寺　晶子, 鍛治屋　浩, 斎藤　琢, 鈴木　穣, 岡部　幸司, Roland Baron, 田中　栄, 鄭　雄一, 北條　宏徳
- Organizer
  第41回日本骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Identifying gene regulatory networks in human skeletal development using human pluripotent stem cells and single cell analysis.2023
- Author(s)
  Hojo H, Tani S, Okada H, Chung UI, Ohba S
- Organizer
  Human Development-from Embryos to Stem Cell Models-Cold Spring Harbor Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] Exploring Gene Regulatory Networks (GRNs) in skeletal development using human Pluripotent Stem Cells (PSCs) and future perspective for clinical applications2023
- Author(s)
  Hironori Hojo
- Organizer
  International Congress of Osteoporosis 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Emerging gene regulatory networks in skeletal development in the mouse and human models2023
- Author(s)
  北條　宏徳
- Organizer
  第41回日本骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Injectable phase-separated tetra-armed polyethylene glycol (PEG) hydrogel scaffold allows sustained release of signaling factors to enhance the repair of cranial bone defects2023
- Author(s)
  Shant Nepal, Jinyan Si, Shohei Ishikawa, Hiroyuki Okada, Shinsuke Ohba, Ung-il Chung, Takamasa Sakai, Hironori Hojo
- Organizer
  ASBMR 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Subcellular sampling and sequencing by iSCseq connects transcriptomics with morphological, physical, and physiological findings in osteoimmunology2023
- Author(s)
  Hiroyuki Okada, Yuta Terui , Yasunori Omata, Masahide Seki , Shoichiro Tani, Junya Miyahara, Kenta Makabe, Asuka Terashima, Sanshiro Kanazawa, Masahiro Hosonuma, Shoko Onodera, Fumiko Yano, Hiroshi Kajiya, Taku Saito, Yutaka Suzuki, Koji Okabe, Roland Baron, Sakae Tanaka, Ung-il Chung, Hironori Hojo
- Organizer
  Cold Spring Harbor Laboratory Meeting “Single Cell Analyses 2023”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Emerging gene regulatory networks in skeletal development in the mouse and human models2023
- Author(s)
  北條　宏徳
- Organizer
  第41回日本骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K10261
[Presentation] Modeling of skeletal development using human pluripotent stem cells and exploring the gene regulatory networks2023
- Author(s)
  Hironori Hojo
- Organizer
  The Korean Society for Biotechnology and Bioengineering (KSBB) 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] 卵黄由来生理活性ペプチドの経口投与は骨粗鬆症と骨形成不全症モデルマウスにおいて骨量と骨強度を改善する2022
- Author(s)
  北浦義昭, 粟田ちひろ, 重光隆成, 青笹正義, 山口基徳, 金武祚, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第21回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-21K19611
[Presentation] Understanding skeletal development through single-cell analysis of human pluripotent stem cell-derived endochondral bone tissues.2022
- Author(s)
  大庭伸介, 谷彰一郎, 岡田寛之, 鄭雄一, 北條宏徳
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Elucidating gene regulatory mechanisms underlying human skeletal development using human pluripotent stem cell-derived bone tissuesand single-cell multiome analysis2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ECTS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Elucidating gene regulatory mechanisms underlying human skeletal development using human pluripotent stem cell-derived bone tissuesand single-cell multiome analysis2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ECTS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Elucidating Gene Regulatory Networks Underlying Human Skeletal Development by Integrating a Model of Human Endochondral Bones and Single-cell Multiomics2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ASBMR 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19883
[Presentation] Elucidating gene regulatory meshanisms underlying human skeletal development by integrating single-cell dynamics of chromatin accessibility and gene expression.2022
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  International Society for Stem Cell Research 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] ELUCIDATING GENE REGULATORY NETWORKS UNDERLYING HUMAN SKELETAL DEVELOPMENT BY INTEGRATING SINGLE-CELL DYNAMICS OF CHROMATIN ACCESSIBILITY AND GENE EXPRESSION2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ISSCR 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] ヒト多能性幹細胞由来の3次元骨組織誘導とシングルセル・マルチオーム解析を用いたヒト骨形成機構の解明.2022
- Author(s)
  谷彰一郎, 岡田寛之, 関真秀, 鈴木穣, 斎藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介：ヒト多能性幹細胞由来の3次元骨組織誘導とシングルセル・マルチオーム解析を用いたヒト骨形成機構の解明.
- Organizer
  第95回日本整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] １細胞多層解析を用いたヒト骨発生における遺伝子制御ネットワークの解明2022
- Author(s)
  谷彰一郎, 岡田寛之, 齊藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第40回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] Elucidating Gene Regulatory Networks Underlying Human Skeletal Development by Integrating a Model of Human Endochondral Bones and Single-cell Multiomics2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ASBMR 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] 転写因子Runx2を中心とした骨発生エンハンサーネットワークの解明.2022
- Author(s)
  北條宏徳, 齋藤琢, 小野寺晶子, 東俊文, 関真秀, 鈴木穣, 饗場篤, 鄭雄一, 大庭伸介
- Organizer
  NGS Expo 2022
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] "Gene regulatory networks underlying human endochondral bone formation "2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ICORS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19589
[Presentation] Elucidating Gene Regulatory Networks Underlying Human Skeletal Development by Integrating a Model of Human Endochondral Bones and Single-cell Multiomics2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ASBMR 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] Understanding mechanisms underlying cell fate specification of dental mesenchymal cells in the developing tooth germ through single-cell transcriptome2022
- Author(s)
  Dahlia Eldeeb, Hironori Hojo, Hiroyuki Okada, Yutaka Suzuki, Masahide Seki, Junichi Tanaka, Shinsuke Ohba, Ung-il Chung
- Organizer
  MBSJ 2022
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] ELUCIDATING GENE REGULATORY NETWORKS UNDERLYING HUMAN SKELETAL DEVELOPMENT BY INTEGRATING SINGLE-CELL DYNAMICS OF CHROMATIN ACCESSIBILITY AND GENE EXPRESSION2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ISSCR 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] The gene expression and epigenetic regulation of individual nuclei within the same osteoclast is heterogeneous: Evidence from Intra-single cell sequencing (iscSeq)2022
- Author(s)
  Hiroyuki Okada, Shoichiro Tani, Yasunori Omata, Asuka Terashima, Taku Saito, Roland Roland, Sakae Tanaka, Ung-il Chung, Hironori Hojo
- Organizer
  第95回日本生化学大会
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] intra-single cell sequencing（iSC-seq）による破骨細胞の多核間制御メカニズム解明2022
- Author(s)
  岡田寛之, 照井悠太, 小俣康徳, 関真秀, 谷彰一郎, 宮原潤也, 真壁健太, 寺島明日香, 金澤三四朗, 細沼雅弘, 矢野文子, 鍛治屋浩, 斎藤琢, 鈴木　穣, 岡部幸司, Roland Baron, 田中栄, 鄭雄一, 北條宏徳
- Organizer
  NGS expo 2022
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] Understanding mechanisms underlying cell fate specification of dental mesenchymal cells in the developing tooth germ through single-cell transcriptome2022
- Author(s)
  Dahlia Eldeeb, Hironori Hojo, Hiroyuki Okada, Yutaka Suzuki, Masahide Seki, Junichi Tanaka, Shinsuke Ohba, Ung-il Chung
- Organizer
  MBSJ 2022
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] 卵黄由来生理活性ペプチドの経口投与は骨粗鬆症と骨形成不全症モデルマウスにおいて骨量と骨強度を改善する.2022
- Author(s)
  北浦義昭, 池田悠希, 森石武史, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19611
[Presentation] "Gene regulatory networks underlying human endochondral bone formation "2022
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ICORS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19883
[Presentation] intra-single cell sequencing( iSC-seq )による破骨細胞の多核間制御メカニズム解明2022
- Author(s)
  岡田寛之、照井悠太、小俣康徳、関真秀、谷彰一郎、宮原潤也、真壁健太、寺島明日香、細沼雅弘、矢野文子、斎藤琢、鈴木穣、Roland Baron、田中栄、鄭雄一、北條宏徳
- Organizer
  第9回日本リウマチ学会ベーシックリサーチカンファ
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] 器官培養系を用いた骨軟骨分化に対する低分子化合物の影響2022
- Author(s)
  下畑宣行、林桜子、北條宏徳、鄭雄一
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K05318
[Presentation] The gene expression and epigenetic regulation of individual nuclei within the same multinucleated osteoclast is heterogeneous: Evidence from Intra-single cell sequencing (iscSeq)2022
- Author(s)
  Hiroyuki Okada, Yuta Terui, Yasunori Omata, Shoichiro Tani, Asuka Terashima, Taku Saito, Roland Baron, Sakae Tanaka, Ung-il Chung, Hironori Hojo
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K10212
[Presentation] 1細胞多層解析を用いたヒト骨発生における遺伝子制御ネットワークの解明.2022
- Author(s)
  谷彰一郎, 岡田寛之, 齋藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] Understanding mechanisms underlying cell fate specification of dental mesenchymal cells in the developing tooth germ through single-cell transcriptome2022
- Author(s)
  Dahlia Eldeeb, Hironori Hojo, Hiroyuki Okada, Yutaka Suzuki, Masahide Seki, Junichi Tanaka, Shinsuke Ohba, Ung-il Chung
- Organizer
  MBSJ 2022
- Data Source
  KAKENHI-PROJECT-22K10261
[Presentation] Elucidating gene regulatory networks underlying human skeletal development by integrating a model of human endochondral bones and single-cell multiomics.2022
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  2022 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] Elucidating gene regulatory meshanisms underlying human skeletal development using human plurioitent stem cell-derived bone tissues and single-cell multiome analysis.2022
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  ECTS (European Calcified Tissue Society) 2022 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] 骨格形成における遺伝子制御ランドスケープの解明2021
- Author(s)
  北條宏徳
- Organizer
  17th Meeting of Bone Biology Forum
- Invited
- Data Source
  KAKENHI-PROJECT-21K19589
[Presentation] Understanding a Mechanism Underlying Bone Repair Process by Combinational Analysis of Lineage Tracing and Single-Cell RNA Sequencing2021
- Author(s)
  Mika Nakayama, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Shinsuke Ohba, Hironori Hojo
- Organizer
  ISSCR 2021
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Elucidating human skeletal development using single-cell analysis by inducing bone tissue formation from human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  2021 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] EXPLORING HUMAN SKELETAL DEVELOPMENT USING AN INDUCED HUMAN BONE TISSUE DERIVED FROM HUMAN PLURIPOTENT STEM CELLS2021
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ISSCR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19883
[Presentation] Exploring human skeletal development using a human bone tissue induced from human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  International Society for Stem Cell Research 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] ヒト多能性幹細胞を用いたヒト骨形成過程の再現と応用2021
- Author(s)
  谷彰一郎, 岡田寛之, 関真秀, 鈴木穣, 斎藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第36回日本整形外科学会基礎集会
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] ヒト多能性幹細胞由来の3次元骨組織誘導とシングルセル・マルチオーム解析を用いたヒト骨形成機構の解明2021
- Author(s)
  谷彰一郎, 岡田寛之, 関真秀, 鈴木穣, 斎藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] 骨髄ニッチを構成する間葉系間質細胞の転写およびエピジェネティック解析による特性解明2021
- Author(s)
  金澤三四朗, 岡田寛之, 北條宏徳, 大庭伸介、古村真, 疋田温彦, 星和人
- Organizer
  第6回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] Elucidating human skeletal development by single-cell analyses with a model of endochondral bone formation using human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  ESA (Endocrine Society of Australia)-SRB (Society for Reproductive Biology)-ANZBMS (Australian and New Zealand Bone and Mineral Society) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] Elucidating human skeletal development using single-cell analysis by inducing bone tissue formation from human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  2021 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19611
[Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021
- Author(s)
  Hironori Hojo
- Organizer
  SICEM 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19589
[Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021
- Author(s)
  Hironori Hojo
- Organizer
  SICEM 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] ヒト多能性幹細胞由来3次元骨組織誘導法と単一細胞解析を用いたヒト骨形成機構の探索2021
- Author(s)
  谷彰一郎, 岡田寛之, 齋藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021
- Author(s)
  Hironori Hojo
- Organizer
  SICEM 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19883
[Presentation] Understanding a mechanism underlying bone repair process and application for bone regeneration2021
- Author(s)
  Hironori Hojo
- Organizer
  SICEM 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05318
[Presentation] 骨格形成における遺伝子制御ランドスケープの解明2021
- Author(s)
  北條宏徳
- Organizer
  17th Meeting of Bone Biology Forum
- Invited
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Elucidating human skeletal development by integrating single-cell analysis and bone tissue induction using human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  ISSCR/JSRM International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Elucidating human skeletal development by integrating single-cell analysis and bone tissue induction using human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  ISSCR/JSRM International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19611
[Presentation] ヒト多能性幹細胞を用いた骨形成過程の再現と応用2021
- Author(s)
  "谷彰一郎,　岡田寛之,　関真秀,　鈴木穣,　齊藤琢,　田中栄,　鄭雄一,　北條宏徳,　大庭伸介 "
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] "ELUCIDATING HUMAN SKELETAL DEVELOPMENT BY INTEGRATING SINGLE-CELL ANALYSIS AND BONE TISSUE INDUCTION USING HUMAN PLURIPOTENT STEM CELLS"2021
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Taku Saito, Sakae Tanaka, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ISSCR tokyo
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] EXPLORING HUMAN SKELETAL DEVELOPMENT USING AN INDUCED HUMAN BONE TISSUE DERIVED FROM HUMAN PLURIPOTENT STEM CELLS2021
- Author(s)
  Shoichiro Tani, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Hironori Hojo and Shinsuke Ohba
- Organizer
  ISSCR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Exploring human skeletal development using a human bone tissue induced from human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  International Society for Stem Cell Research 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Understanding skeletal development through single-cell analysis of human pluripotent stem cell-derived endochondral bone tissues.2021
- Author(s)
  大庭伸介, 谷彰一郎, 岡田寛之, 鄭雄一, 北條宏徳
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21494
[Presentation] ヒト多能性幹細胞由来3次元骨組織誘導法と単一細胞解析を用いたヒト骨形成機構の探索2021
- Author(s)
  谷彰一郎, 岡田寛之, 齊藤琢, 田中栄, 鄭雄一, 北條宏徳, 大庭伸介
- Organizer
  第39回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Elucidating human skeletal development by single-cell analyses with a model of endochondral bone formation using human pluripotent stem cells.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  ESA (Endocrine Society of Australia)-SRB (Society for Reproductive Biology)-ANZBMS (Australian and New Zealand Bone and Mineral Society) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Elucidating dynamic gene regulatory networks in human skeletal development using single cell analyses on a human pluripotent stem cell-based model of endocohondoral ossification.2021
- Author(s)
  Tani S, Okada H, Seki M, Suzuki Y, Saito T, Tanaka S, Chung UI, Hojo H, Ohba S
- Organizer
  ASHBi Symposium 2021
- Data Source
  KAKENHI-PROJECT-21K19611
[Presentation] Understanding a Mechanism Underlying Bone Repair Process by Combinational Analysis of Lineage Tracing and Single-Cell RNA Sequencing2021
- Author(s)
  Mika Nakayama, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Shinsuke Ohba, Hironori Hojo
- Organizer
  ISSCR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19883
[Presentation] Understanding a Mechanism Underlying Bone Repair Process by Combinational Analysis of Lineage Tracing and Single-Cell RNA Sequencing2021
- Author(s)
  Mika Nakayama, Hiroyuki Okada, Masahide Seki, Yutaka Suzuki, Ung-il Chung, Shinsuke Ohba, Hironori Hojo
- Organizer
  ISSCR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04952
[Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development2020
- Author(s)
  Hironori Hojo, Taku Saito, Shoko Onodera, Toshifumi Azuma, Ung-il Chung, Masahide Seki, Yutaka Suzuki, Andrew P. McMahon, Shinsuke Ohba
- Organizer
  American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development2020
- Author(s)
  Hojo H, Saito T, Onodera S, Azuma T, Chung UI, Seki M, Suzuki Y, McMahon AP, Ohba S
- Organizer
  American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development2020
- Author(s)
  Hironori Hojo, Taku Saito, Shoko Onodera, Toshifumi Azuma, Ung-il Chung, Masahide Seki, Yutaka Suzuki, Andrew P. McMahon, Shinsuke Ohba
- Organizer
  American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19636
[Presentation] Runx2は骨格発生においてクロマチンランドスケープを規定する2020
- Author(s)
  北條宏徳、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
- Organizer
  日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-18K19636
[Presentation] Runx2は骨格発生においてクロマチンランドスケープを規定する2020
- Author(s)
  北條宏徳、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
- Organizer
  日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] Runx2 defines the osteoblast chromatin landscape in skeletal development.2020
- Author(s)
  Hojo H, Saito T, Onodera S, Azuma T, Chung UI, Seki M, Suzuki Y, McMahon AP, Ohba S
- Organizer
  42nd Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19635
[Presentation] Runx2は骨格発生においてクロマチンランドスケープを規定する2020
- Author(s)
  北條宏徳、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
- Organizer
  第38回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-20H03885
[Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する2019
- Author(s)
  北條宏徳、山川晃、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19636
[Presentation] De novo missense mutation in SP7 in a patient with cranial hyperostosis, long bone fragility, and increased osteoblast number.2019
- Author(s)
  Lui J, Raimann A, Dong L, Hojo H, Roschger P, Fratzl-Zelman N, Jee YH, Haeusler G, Baron J
- Organizer
  2019 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する2019
- Author(s)
  北條宏徳、山川晃、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes.2019
- Author(s)
  Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP.
- Organizer
  2019 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19636
[Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する2019
- Author(s)
  1.北條宏徳、山川晃、齋藤琢、小野寺晶子、東俊文、鄭雄一、大庭伸介
- Organizer
  第37回日本骨代謝学会学術集会,
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Identification of bone marrow mesenchymal stromal cell population and stem cell niche signal.2019
- Author(s)
  Kanazawa S, Hojo H, Ohba S, Hikita A, Hamada Y, Hoshi K
- Organizer
  International Society for Stem Cell Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19635
[Presentation] A Novel SP7/OSTN Axis Controls Osteocyte Morphology and Function2019
- Author(s)
  Wang JS, Mirzamohammadi F, Hojo H, Rotter D, Castro Andrade CD, Fiscaletti M, Kronenberg HM, Wein MN
- Organizer
  2019 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes.2019
- Author(s)
  Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP.
- Organizer
  2019 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] A chondrocyte-specific Indian hedgehog enhancer as an OA-driving enhancer.2019
- Author(s)
  Yamakawa A, Hojo H, Chung UI, Ohba S
- Organizer
  Orthopedic Research Society 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19636
[Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes2019
- Author(s)
  Hojo H, Ohba S et al
- Organizer
  2019 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02998
[Presentation] A chondrocyte-specific indian hedgehog enhancer as an OA-driving enhancer2019
- Author(s)
  Yamakawa Akira, Hojo Hironori, Chung Ung-il, Ohba Shinsuke
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02998
[Presentation] Runx2は骨格発生において細胞種特異的な転写制御領域に作用する.2019
- Author(s)
  北條宏徳, 山川晃, 齋藤琢, 小野寺晶子, 東俊文, 鄭雄一, 大庭伸介
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Cell-type disctinct Runx2 regulatory action underlies its distinct functions in osteoblast and chondrocytes.2019
- Author(s)
  Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP
- Organizer
  American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] A chondrocyte-specifc Indian hedgehog enhancer as an OA-driving enhancer2019
- Author(s)
  Akira Yamakawa, Hironori Hojo, Ung-il Chung, Shinsuke Ohba
- Organizer
  Orthopaedic Research Society (ORS) 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Cell-type-distinct regulatory action of Runx2 on the genome underlies its distinct roles in osteoblasts and chondrocytes.2019
- Author(s)
  Hojo H, Ohba S, Yamakawa A, Guo Q, He X, Saito T, Onodera S, Azuma T, Chung UI, McMahon AP.
- Organizer
  2019 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Generation of functional salivary gland organoid from mouse embryonic stem cells by Sox9 and Foxc1 transduction.2019
- Author(s)
  Tanaka J, Ogawa M, Hojo H, Mabuchi Y, Yasuhara R, Takamatsu K, Ohba S, Tsuji T, Mishima K
- Organizer
  International Society for Stem Cell Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19635
[Presentation] Identification of a chondrocyte-specific Indian hedgehog enhancer and Sox9-mediated mechanisms of the enhancer activation2018
- Author(s)
  Yamakawa A, Hojo H, Chung UI, Ohba S
- Organizer
  OARSI World Congress on Osteoarthritis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Role of Osterix (SP7) in Regulating Osteocyte Biology and Dendrite Formation2018
- Author(s)
  Mirzamohammadi F, Hojo H, Enishi T, Govea N, Kronenberg HM, Wein MN
- Organizer
  2018 Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Identification of a chondrocyte-specific Indian hedgehog enhancer and Sox9-mediated mechanisms of the enhancer activation2018
- Author(s)
  Akira Yamakawa, Hironori Hojo, Ung-il Chung, Shinsuke Ohba
- Organizer
  2018 OARSI World Congress on Osteoarthritis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Identification of a chondrocyte-specific Indian hedgehog enhancer and Sox9-mediated mechanisms of the enhancer activation2018
- Author(s)
  Yamakawa Akira, Hojo Hironori, Chung Ung-il, Ohba Shinsuke
- Organizer
  2018 OARSI World Congress on Osteoarthritis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02998
[Presentation] 軟骨細胞特異的なIndian hedgehogのエンハンサーの同定とSox9による活性化機構2018
- Author(s)
  山川晃, 北條宏徳, 鄭雄一, 大庭伸介
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] Enhancer network for Ihh transcription in chondrocytes.2017
- Author(s)
  Yamakawa A, Hojo H, Chung UI, Ohba S
- Organizer
  Orthopaedic Research Society (ORS) 2017 Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] Modeling of bone remodeling by three-dimensional co-culture of mouse embryonic stem cell-derived osteoblasts and osteoclast precursors2017
- Author(s)
  Zujur DC, Hikita A, Kanke K, Hojo H, Chung UI, Ohba S
- Organizer
  International Society for Stem Cell Research 15th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Modeling of bone remodeling by three-dimensional co-culture of mouse embryonic stem cell-derived osteoblasts and osteoclast precursors.2017
- Author(s)
  Zujur DC, Hikita A, Kanke K, Hojo H, Chung UI, Ohba S
- Organizer
  International Society for Stem Cell Research 15th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] In vivo bone formation by osteoblasts generated from human induced pluripotent stem cells under fully defined xeno-free conditions.2017
- Author(s)
  Zujur DC, Kanke K, Hojo H, Onodera S, Azuma T, Chung UI, Ohba S
- Organizer
  39th Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] 軟骨細胞特異的なIhhのエンハンサーの同定とSox9によるその活性化機構.2017
- Author(s)
  山川晃, 北條宏徳, 鄭雄一, 大庭伸介
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] A system level investigation to unravel mechanisms and potential direct targets of the osteogenic small molecule TH2017
- Author(s)
  Ichsan M, Kanke K, Hojo H, Chung UI, Ohba S
- Organizer
  EMBL Conference: Mammalian Genetics and Genomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] Modeling of bone remodeling by three-dimensional co-culture of mouse embryonic stem cell-derived osteoblasts and osteoclast precursors.2017
- Author(s)
  Zujur DC, Hikita A, Kanke K, Hojo H, Chung UI, Ohba S
- Organizer
  International Society for Stem Cell Research 15th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04403
[Presentation] 軟骨細胞におけるエンハンサーネットワークを介したIndian hedgehogの発現制御機構.2017
- Author(s)
  山川晃, 北條宏徳, 鄭雄一, 大庭伸介
- Organizer
  第90回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] In vivo bone formation by osteoblasts generated from human induced pluripotent stem cells under fully defined xeno-free conditions2017
- Author(s)
  Zujur DC, Kanke K, Hojo H, Onodera S, Azuma T, Chung UI, Ohba S
- Organizer
  39th Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05106
[Presentation] In vivo bone formation by osteoblasts generated from human induced pluripotent stem cells under fully defined xeno-free conditions.2017
- Author(s)
  Zujur DC, Kanke K, Hojo H, Onodera S, Azuma T, Chung UI, Ohba S
- Organizer
  39th Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312
[Presentation] Hedgehog agonist promotes callus formation in a mouse fracture model.2017
- Author(s)
  Kashiwagi M, Hojo H, Kitaura Y, Maeda Y, Aini H, Takato T, Chung UI, Ohba S
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312

1. Ohba Shinsuke (20466733)

# of Collaborated Projects: 14 results

# of Collaborated Products: 89 results
2. Tei Yuichi (30345053)

# of Collaborated Projects: 4 results

# of Collaborated Products: 42 results
3. 酒井崇匡 (70456151)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 岡田寛之 (10883481)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
5. Hoshi Kazuto (30344451)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 疋田温彦 (60443397)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 金澤三四朗 (60823466)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 森石武史 (20380983)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 松尾友紀 (40792601)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 小俣康徳 (40570734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. Takato Tsuyoshi (90171454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Okayasu Mari (10610941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 位高啓史 (60292926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 菅家康介 (90779810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 下畑宣行 (30419709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 関真秀 (90749326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 田中栄 (50282661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 齋藤琢 (30456107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 高柳広 (20334229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 藤尾圭志 (70401114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 鈴木穣 (40323646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 寺島明日香 (30596937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 井上登紀子 (70240736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 大久保和美 (10396715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 西條英人 (80372390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 矢野文子 (80529040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 小笠原徹 (20359623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 細沼雅弘 (20836457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 行森茜 (60813748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 美島健二 (50275343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 田中準一 (40710166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 安原理佳 (20453649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. ZUJUR Denise

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. ABE Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 井上富雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 中村史朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 家崎高志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 千々松良太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 岩永康秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 森大典

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hojo Hironori 北條 宏徳

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ヒト内軟骨性骨化を模倣する骨オルガノイド法の開発と骨系統疾患の研究基盤の構築Principal Investigator

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Development of a functional GWAS-SNP detection method using single-cell CRISPR screening methodPrincipal Investigator

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Comparative Analysis of Epigenomic Dynamics in Bone Development and Repair and its Application to Bone RegenerationPrincipal Investigator

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Development of functional enhancer screening system by integrating genome editing technology with single-cell RNA-seqPrincipal Investigator

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Hojo Hironori 北條宏徳

[Book] 先進医療NAVIGATOR 再生医療・細胞医療の研究と産業化の最前線第２章 14 骨再生医療等の現状と課題2019