nakakaji rina 中鍛治里奈

… Alternative Names

NAKAKAJI Rina 中鍛治里奈

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Researcher Number	80845511
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2019 – 2023: 横浜市立大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / 0907:Oral science and related fields Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Basic Section 90110:Biomedical engineering-related / Basic Section 53020:Cardiology-related / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator 口腔癌 / 口腔がん / EP４ / ミトコンドリア / PGE2受容体 / ミトコンドリア呼吸能 / EP4 / Fe(Salen) / 磁性抗癌剤 / 鉄アセン … More / 磁性体 / ドラッグデリバリー / 医工連携研究 / 磁性化 / 有機磁性体 … More Except Principal Investigator 交流磁場 / EP4 / 口腔癌 / ハイパーサーミア / すい臓がん細胞 / 抗細胞増殖作用 / ｃAMP / 心筋保護 / 心機能 / Epac / cAMP / 交感神経 / 頸部転移マウスモデル / 遊走能抑制効果 / 心臓線維化 / 細胞遊走 / p21 / p53 / 心毒性 / Orai1 / ドキソルビシン / 心臓線維芽細胞 / Geranylgeraniol / クロモン誘導体 / ハイパーサミア / マイルドハイパーサーミア / 併用療法 / 腫瘍選択性磁性体 / 低侵襲性治療 / 癌細胞特異的指向性酸化鉄微粒子 / 近赤外線 / 磁性酸化鉄ナノ粒子 / ICG / 新規癌指向性磁性酸化鉄ナノ粒子 / 細胞透過性ペプチド Less

心臓線維芽細胞におけるドキソルビシンの心毒性メカニズムの解析
- Principal Investigator
  
  梅村将就
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Yokohama City University
口腔癌における交流磁場が持つ遊走能抑制効果の分子生物学的研究
- Principal Investigator
  
  光藤健司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Yokohama City University
Molecular mechanism of magnetic sensor in pancreatic cancer cells
- Principal Investigator
  
  石川義弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Yokohama City University
PGE2受容体EP4の口腔癌における遊走性亢進作用のメカニズム解析Principal Investigator
- Principal Investigator
  
  中鍛治里奈
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Yokohama City University
Development of minimally invasive therapy for oral cancer by hyperthermia with tumor-specific targeting magnetic nanoparticles
- Principal Investigator
  
  Tohnai Iwai
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Meikai University
Development of oral cancer therapy using the novel magnetic anti-cancer medicinePrincipal Investigator
- Principal Investigator
  
  NAKAKAJI Rina
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0907:Oral science and related fields
- Research Institution
  Yokohama City University
Regulation of cardiac function by the autonomic nervous system
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Yokohama City University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Potentiation of anticancer activity of G<sub>2</sub>/M blockers by mild hyperthermia2023
- Author(s)
  Tagawa Y, SAKAGAMI H, TANUMA S, AMANO S, UOTA S, BANDOW K, TOMOMURA M, UESAWA Y, TAKAO K, SUGITA Y, YAMAMOTO N, SAKASHITA H, NAKAKAJI R, KOIZUMI T, MITSUDO K, TOHNAI I
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 8 Pages: 3429-3439
- DOI
  10.21873/anticanres.16518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03893
[Journal Article] Physiological Functions of Calcium Signaling via Orai1 in Various Cancers2023
- Author(s)
  Umemura M, Nakakaji R, Ishikawa Y
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 73 Issue: 1 Pages: 21-21
- DOI
  10.1186/s12576-023-00878-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06928, KAKENHI-PROJECT-23K25180
[Journal Article] Store-operated calcium entry via ORAI1 regulates doxorubicin-induced apoptosis and prevents cardiotoxicity in cardiac fibroblasts2022
- Author(s)
  Nemoto H, Umemura M, Suzuki F, Nagasako A, Nagao K, Hidaka Y, Nakakaji R, Uchida K, Suzuki S, Masuda M, Ishikawa Y,
- Journal Title
  
  PLoS One
  
  Volume: 17(12) Issue: 12 Pages: e0278613-e0278613
- DOI
  10.1371/journal.pone.0278613
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06928, KAKENHI-PROJECT-19H03657, KAKENHI-PROJECT-23K25180
[Presentation] 口腔がんの転移はEP4-CaMKK2シグナルを介して促進する2024
- Author(s)
  石川聡一郎, 中鍛治里奈, 山下絵利子, 大澤昂平, 來生知 ,光藤健司
- Organizer
  第42回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K10154
[Presentation] PYK2 regulates PD-1L1 Expression via JAK/STAT signaling in melanoma.2023
- Author(s)
  Mizuno Y, Umemura M, Suzuki F, Nakakaji R, Yamaguchi Y, Ishikawa Y.
- Organizer
  First international Societies for investigative Dermatology Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25180
[Presentation] IFN-γ regulates PD-L1 transcription via PYK2 in melanoma2023
- Author(s)
  鈴木文菜, 水野雄斗, 梅村将就, 永迫茜, 中鍛治里奈, 長尾景充, 石川聡一郎, 石川義弘
- Organizer
  第100回日本生理学会大会, 京都, 2023,3.
- Data Source
  KAKENHI-PROJECT-22K06928
[Presentation] EP4は口腔がん細胞のミトコンドリアの呼吸と生合成を亢進する2023
- Author(s)
  中鍛治里奈
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-23K25180
[Presentation] EP4 promotes mitochondrial respiration and biogenesis2023
- Author(s)
  中鍛治里奈, 梅村将就, 石川聡一郎, 永迫茜, 長尾景充, 水野雄斗, 大澤昂平, 石川義弘
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K15492
[Presentation] Heated Tobacco Products (HTPs) Promotes Cell Proliferation in Human Oral Cancer Cells2023
- Author(s)
  長尾景充, 梅村将就, 髙安笙太, 鈴木文菜, 水野雄斗, 石川聡一郎, 中鍛治里奈, 永迫茜, 堀之内孝広, 山本哲哉, 石川義弘
- Organizer
  第100回日本生理学会大会, 京都, 2023,3.
- Data Source
  KAKENHI-PROJECT-22K06928
[Presentation] EP4 promoted cell migration via mitochondrial biogenesis in oral cancer cells.2023
- Author(s)
  Ishikawa S, Umemura M, Nakakaji R, Nagasako A, Nagao K, Mizuno Y, Suzuki F, Osawa K, Kioi M, Mitsudo K, Ishikawa Y.
- Organizer
  American Association for Cancer Research 2023 Annual Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25180
[Presentation] 口腔癌に対する磁性ナノ粒子の動注療法と近赤外線を用いた組織内温熱療法の有効性2023
- Author(s)
  小倉寛哉、天野滋、坂上宏、田沼靖一、山本信治、中鍛治里奈、小泉敏之、光藤健司、藤内祝
- Organizer
  第68回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20H03893
[Presentation] EP4 promoted cell migration via mitochondrial biogenesis in oral cancer cells2023
- Author(s)
  Ishikawa S, Umemura M, Nakakaji R, Nagasako A, Nagao K, Mizuno Y, Suzuki F, Osawa K, Kioi M, Mitsudo K, Ishikawa Y
- Organizer
  The American Association for Cancer Research Annual Meeting (AACR 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06928
[Presentation] 口腔癌に対するICG/Au/Ferucarbotran結合腫瘍細胞透過性ペプチドの動注療法とNIRを用いた細胞内温熱療法2023
- Author(s)
  小倉寛哉、天野滋、坂上宏、田沼靖一、山本信治、中鍛治里奈、小泉敏之、光藤健司、藤内祝
- Organizer
  第40回日本ハイパーサーミア学会
- Data Source
  KAKENHI-PROJECT-20H03893
[Presentation] EP4 increases the mitochondrial respiration and promotes cell migration in oral cancer2023
- Author(s)
  Nakakaji R, Umemura M, Osawa K, Ishikawa S, Mitsudok K, Ishikawa Y
- Organizer
  The American Association for Cancer Research Annual Meeting (AACR 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06928
[Presentation] EP4 increases the mitochondrial respiration and promotes cell migration in oral cancer.2023
- Author(s)
  Nakakaji R, Umemura M, Osawa K, Ishikawa S, Mitsudo K, Ishikawa Y.
- Organizer
  American Association for Cancer Research 2023 Annual Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25180
[Presentation] 口腔がん細胞におけるEP4受容体のミトコンドリア生合成を介した遊走調節機構の解明.2023
- Author(s)
  石川聡一郎, 梅村将就, 中鍛治里奈, 永迫茜, 大澤昂平, 深江和奏, 山下絵利子, 光藤健司, 石川義弘.
- Organizer
  第32回日本病態生理学会.
- Data Source
  KAKENHI-PROJECT-23K25180
[Presentation] EP4は口腔がん細胞のミトコンドリアの呼吸と生合成を亢進する.2023
- Author(s)
  中鍛治　里奈
- Organizer
  日本生理学会第100回記念大会.
- Data Source
  KAKENHI-PROJECT-23K25180
[Presentation] EP4 promotes mitochondrial respiration and biogenesis in oral cancer cells2023
- Author(s)
  中鍛治里奈, 梅村将就, 石川聡一郎, 永迫茜, 長尾景充, 水野雄斗, 大澤昂平, 石川義弘
- Organizer
  第100回日本生理学会大会, 京都, 2023,3.
- Data Source
  KAKENHI-PROJECT-22K06928
[Presentation] EP4 increases the mitochondrial respiration and promotes cell migration in oral cancer2023
- Author(s)
  Rina Nakakaji, Masanari Umemura, Kohei Osawa, Soichiro Ishikawa, Kenji Mitsudo, Yoshihiro Ishikawa
- Organizer
  American Association for Cancer Research Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15492
[Presentation] EP4受容体は口腔がん細胞においてミトコンドリアの生合成を介して細胞遊走を促進する2023
- Author(s)
  石川聡一郎, 中鍛治里奈, 山下絵利子, 大澤昂平, 來生知 ,光藤健司
- Organizer
  第68回　日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K10154
[Presentation] EP4 promoted cell migration via mitochondrial biogenesis in oral cancer cells2023
- Author(s)
  石川聡一郎, 梅村将就, 中鍛治里奈, 永迫茜, 長尾景充, 水野雄斗, 大澤昂平, 來生知, 光藤健司, 石川義弘
- Organizer
  第100回日本生理学会大会, 京都, 2023, 3.
- Data Source
  KAKENHI-PROJECT-22K06928
[Presentation] 口腔がん細胞に対する G2/M ブロッカーとマイルドハイパーサーミアの併用効果2022
- Author(s)
  田川裕也、坂上宏、天野滋、田沼靖一、山本信治、坂下英明、中鍛治里奈、小泉敏之、光藤健司、藤内祝
- Organizer
  第39回日本ハイパーサーミア学会大会 2022
- Data Source
  KAKENHI-PROJECT-20H03893
[Presentation] 口腔がん細胞遊走におけるEP4受容体のCa2+シグナルを介したメカニズムの解明2022
- Author(s)
  石川聡一郎, 梅村将就, 内野萌, 中鍛治里奈, 永迫茜, 大澤昂平, 來生知, 光藤健司, 石川義弘
- Organizer
  第31回日本病態生理学会大会, 岐阜, 2022.
- Data Source
  KAKENHI-PROJECT-22K06928
[Presentation] 口腔がん細胞遊走におけるEP4受容体のCa2+シグナルを介したメカニズムの解明.2022
- Author(s)
  石川聡一郎, 梅村将就, 内野萌, 中鍛治里奈, 永迫茜, 大澤昂平, 來生知, 光藤健司, 石川義弘.
- Organizer
  第31回日本病態生理学会大会.
- Data Source
  KAKENHI-PROJECT-23K25180
[Presentation] ドキソルビシンの心毒性メカニズムの解析.2022
- Author(s)
  鈴木文菜, 梅村将就, 内野萌, 根本寛子, 日髙祐子, 永迫茜, 中鍛治里奈, 石川義弘
- Organizer
  第30回日本病態生理学会大会, (ハイブリッド開催), 福岡, 2022, 1.
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] Physiological analysis of doxorubicin-induced cardiotoxicity in H9C2 cells.2022
- Author(s)
  鈴木文菜, 梅村将就, 内野萌, 根本寛子, 日髙祐子, 永迫茜, 中鍛治里奈, 石川義弘.
- Organizer
  第99回日本生理学会大会,（ハイブリッド開催）, 仙台, 2022.3.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] Doxorubicin (DOX) Induces Fibrotic Change in Cardiac Fibroblasts. 病態生理の視点からの臓器線維化メカニズムの探索.2022
- Author(s)
  梅村将就, 成川雅俊, 鈴木文菜, 根本寛子, 永迫　茜, 中鍛治里奈, 石川義弘.
- Organizer
  第99回日本生理学会大会,（ハイブリッド開催）, 仙台, 2022,3.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] ストア作動性カルシウム流入機構を介するドキソルビシン関連心不全の新たな機序.2022
- Author(s)
  根本寛子, 梅村将就, 中鍛治里奈, 永迫　茜, 長尾景充, 日高祐子, ISLAM RAFIKUL, 石川聡一郎, 水野雄斗, 内野　萌, 鈴木文菜, 鈴木伸一, 石川義弘.
- Organizer
  第99回日本生理学会大会,（ハイブリッド開催）, 仙台, 2022,3.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] 心臓線維芽細胞におけるOrai1を介したドキソルビシン関連心不全の新たな機序.2022
- Author(s)
  根本寛子,梅村将就, 中鍛治里奈, 永迫茜, 長尾景充, 日高祐子, Rafikul Islam, 鈴木文菜, 鈴木伸一, 石川義弘.
- Organizer
  第30回日本病態生理学会大会, (ハイブリッド開催), 福岡, 2022, 1.
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] ドキソルビシンが心臓線維芽細胞へ与える影響と心臓障害の新たなメカニズム．2021
- Author(s)
  根本寛子, 梅村将就, 中鍛治里奈, 永迫茜, 長尾景充, 日髙祐子,Md Rafikul Islam, 石川聡一郎, 水野雄斗, 鈴木文菜, 鈴木伸一, 石川義弘.
- Organizer
  生理学研究所研究会,　(WEB開催), 2021,11.
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] ヒト口腔扁平上皮がん細胞に対する抗がん剤および過酸化水素とマイルドハイパーサーミアの併用効果2021
- Author(s)
  田川裕也、坂上宏、天野滋、友村美根子、坂東健二郎、高尾浩一、杉田義昭、植沢芳広、山本信治、坂下英明、中鍛治里奈、小泉敏之、光藤健司、藤内祝
- Organizer
  ハイパーサーミア学会
- Data Source
  KAKENHI-PROJECT-20H03893
[Presentation] 口腔がん細胞に対する抗がん剤および過酸化水素とマイルドハイパーサーミアの併用効果2021
- Author(s)
  田川裕也１）、坂上宏２）、天野滋２）、山本信治１）、坂下英明１）、中鍛治里奈３）、小泉敏之４）、光藤健司４）、藤内祝５）
- Organizer
  口腔外科学会
- Data Source
  KAKENHI-PROJECT-20H03893
[Presentation] ドキソルビシンが心臓線維芽細胞へ与える影響と心臓障害の新たなメカニズム．2021
- Author(s)
  根本寛子, 梅村将就, 中鍛治里奈，永迫茜，長尾景充，日髙祐子，Md Rafikul Islam，石川聡一郎，水野雄斗，鈴木文菜，鈴木伸一，石川義弘.
- Organizer
  生理学研究所研究会.
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] 心臓線維芽細胞に対するドキソルビシンの線維化促進作用．2020
- Author(s)
  梅村将就，田中　遼，成川雅俊，中鍛治里奈，Islam R，大澤昂平，引地真由，石川義弘
- Organizer
  第93回日本薬理学会年会（WEB開催）
- Data Source
  KAKENHI-PROJECT-19H03657
[Presentation] Prostaglandin E2 receptor EP4 regulates fibrotic changes via intracellular calcium in cardiac fibroblast cells．2019
- Author(s)
  Umemura M，Osawa K，Ryo T，Hikichi M，Nakakaji R，Ishikawa Y.
- Organizer
  American Heart Association’s Scientific Sessions.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03657

1. 梅村将就 (50595353)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. ISHIKAWA Yoshihiro (40305470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
3. 光藤健司 (70303641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. 永迫茜 (70902675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. 長尾景充 (40903654)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
6. Tohnai Iwai (50172127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 杉田義昭 (20255029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 友村美根子 (30217559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 坂上宏 (50138484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. 坂東健二郎 (50347093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 山本信治 (60385185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. 高尾浩一 (70337484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 小泉敏之 (80323575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. 天野滋 (90167958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. 植沢芳広 (90322528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 坂下英明 (10178551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 奥平准之 (10635585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中村隆 (30772371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 奥村敏 (60233475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 横山詩子 (70404994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

nakakaji rina 中鍛治 里奈

NAKAKAJI Rina 中鍛治 里奈

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心臓線維芽細胞におけるドキソルビシンの心毒性メカニズムの解析

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口腔癌における交流磁場が持つ遊走能抑制効果の分子生物学的研究

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Molecular mechanism of magnetic sensor in pancreatic cancer cells

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PGE2受容体EP4の口腔癌における遊走性亢進作用のメカニズム解析Principal Investigator

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Development of minimally invasive therapy for oral cancer by hyperthermia with tumor-specific targeting magnetic nanoparticles

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Development of oral cancer therapy using the novel magnetic anti-cancer medicinePrincipal Investigator

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Regulation of cardiac function by the autonomic nervous system

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[Journal Article] Potentiation of anticancer activity of G<sub>2</sub>/M blockers by mild hyperthermia2023

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[Journal Article] Physiological Functions of Calcium Signaling via Orai1 in Various Cancers2023

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[Journal Article] Store-operated calcium entry via ORAI1 regulates doxorubicin-induced apoptosis and prevents cardiotoxicity in cardiac fibroblasts2022

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[Presentation] 口腔がんの転移はEP4-CaMKK2シグナルを介して促進する2024

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[Presentation] PYK2 regulates PD-1L1 Expression via JAK/STAT signaling in melanoma.2023

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[Presentation] IFN-γ regulates PD-L1 transcription via PYK2 in melanoma2023

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[Presentation] EP4は口腔がん細胞のミトコンドリアの呼吸と生合成を亢進する2023

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[Presentation] EP4 promotes mitochondrial respiration and biogenesis2023

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nakakaji rina 中鍛治里奈

NAKAKAJI Rina 中鍛治里奈