Itoh Tsunetoshi 伊藤恒敏

… Alternative Names

ITOH Tsunetoshi 伊藤恒敏

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Researcher Number	90004746
Affiliation (based on the past Project Information) *help	2015 – 2017: 東北福祉大学, 健康科学部, 教授 2007 – 2011: Tohoku University, Graduate School of Medicine, Professor 2006: 東北大学, 大学院医学系研究科, 教授 1999 – 2005: School of medicine, Tohoku Univ., Professor, 大学院・医学系研究科, 教授 2001 – 2002: 東北大学, 大学院・医学研究科, 教授 1994 – 1998: 東北大学, 医学部, 教授 1991 – 1992: TOHOKU UNIVERSITY SCHOOL OF MEDICINE, DEPARTMENT OF ANATOMY, PROFESSOR, 医学部, 教授
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) / General anatomy (including histology/embryology) Except Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) / Orthopaedic surgery / Digestive surgery
Keywords	Principal Investigator Thymus / 胸腺 / Microenvironment / Selection / Differentiation / Thymocytes / 微小環境 / 小腸 / パーフォリン / DNA断片化 … More / Cell death / Apoptosis / Clonal deletion / 細胞死 / 選択 / 分化 / 胸腺リンパ球 / 上皮細胞 / マウス / IEL / DNA修復 / 抗CD3抗体 / Perforin / Granzyme B / 粘膜固有層 / マクロファージ / グランザイム / TNFα / γδ-IELs / T lymphocyte / Cytokine / Lineage commitment / Hematopoietic stem cells / Tリンパ球 / サイトカイン / 系統分化 / 造血幹細胞 / TCR / Gene expression / Surface marker / Cell sorter / 同定 / セルソーティング / T細胞抗原受容体 / 遺伝子発現 / 表面マーカー / セルソーター / 肢芽 / pyknosis / apoptosis / アポトーシス / クローン排除 / Cell-cell interaction / Colony-stimulating factors / Stromal cells / Hemopoiesis / Fetal liver hemopoiesis / Fetal liver / Liver / GMーCSF / MーCSF / 造血前駆細胞 / 造血支持機能 / 胎生肝 / 細胞間相互作用 / コロニー増殖因子 / 支質細胞 / 造血 / 肝細胞 / 胎仔肝 / 肝 / Flow Cytometer / in vivo / グランザイムB / iIEL / 絨毛上皮細胞 / Flow Cytometry / 電子顕微鏡 / 免疫組織化学 / TNF / 腸上皮内リンパ球(IEL) / TUNEL法 / 小腸絨毛粘膜上皮 … More Except Principal Investigator Rad50 / γ-H2AX / v-ATPase / MMP / IL-6 / CAPD / 抗CD3抗体 / DNA修復 / DNA断片化 / 破骨細胞 / Antigen recognition / Antigen specificity / MHC / Thymic development / Thymic selection / T cell receptor / 胸腺 / 分化 / 選択 / Tリンパ球 / 抗原認識 / 抗原特異性 / 主要組織適合性抗原 / 胸腺分化 / 胸腺選択 / T細胞受容体 / Mrell / DNA repair / DNA fragmentation / anti-CD3 mAb / intra-epithelial lymphocyte (IEL) / intestinal epithelial cells (IEC) / パーフォリン / TNFα / Mre11 / 上皮細胞間リンパ球 / 小腸絨毛上皮細胞 / synovial cell / Rheumatoid arthritis / 滑膜細胞 / 関節リウマチ / Elastase / Collagen-induced arthritis / Bisphosphonate / Neutrophils / Bone Destruction / Rheumatoid Arthritis / 造血 / ビスフォスフォネト / エラスターゼ / コラーゲン誘導関節炎 / ビスフォスフォネート / 好中球 / 骨破壊 / 慢性リウマチ性関節炎 / cytokine / peritoneal lavage / salt solution / 侵襲 / 生理的食塩水 / サイトカイン / 腹腔洗浄 / 生理食塩水 / in vivo / 電子顕微鏡 / 免疫組織化学 / 上皮細胞 / iIEL / 小腸 / 脾臓 / 骨髄 / 顆粒球 / 赤血球造血 / マクロファージ / ビスフオスフオネート Less

Analysis of the autocrine DNA fragmentation mechanisms in mouse intestinal intraepithelial lymphocytesPrincipal Investigator
- Principal Investigator
  
  Itoh Tsunetoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Tohoku Fukushi University
Distribution of Intraepithelial lymphocytes in the murine small intestine : The variability of the morphological property and functionPrincipal Investigator
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
DNA fragmentation of mouse small intestinal epithelial cells by iIEL and DNA repair in the epithelial cells
- Principal Investigator
  
  OGATA Masaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
Explore the cause of CDR3 shortening during thymocyte selection
- Principal Investigator
  
  OGATA Masaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
Factors determining T lineage commitment in haematopoietic stem cell.Principal Investigator
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
DNA fragmentation factor of small intestinal enterocyte induced by activation of intraepithelial lymphocyte
- Principal Investigator
  
  MATSUTANI Takaji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
アポトーシス誘導後の断片化DNAの修復Principal Investigator
- Principal Investigator
  
  伊藤恒敏
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
Analysis of gene expression in FACS-sorted thymocytesPrincipal Investigator
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
The proton release mechanism in synovial fibroblasts of rheumatoid arthritis
- Principal Investigator
  
  OHTSU Susumu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tohoku University
Analysis of the mechanism of bone destruction by neutrophils
- Principal Investigator
  
  NAKAMURA Masanori
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Showa University
  Tohoku University
Mechanisms of pyknotic cell death in vivo and their biological significancePrincipal Investigator
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  TOHOKU UNIVERSITY
Development of new composition of peritoneal savage fluids
- Principal Investigator
  
  SHINEHA Ryuzaburo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHOKU UNIVERSITY
Microenvironment for thymocyte differentiation, selection and clonal eliminationPrincipal Investigator
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
アミノビスフオスフオネートの赤血球造血特にマクロファージへの効果
- Principal Investigator
  
  NAKAMURA Masanori
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
ANALYSIS OF HEMOPOIETIC MECHANISMS IN THE FETAL LIVER USING AN ESTABLISHED FETAL HEPATOCYTIC CELL CLONEPrincipal Investigator
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University

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All Journal Article Presentation

[Journal Article] マウス小腸におけるIELの活性化および転帰の形態学的解析2016
- Author(s)
  尾形雅君, 香川慶輝, 安本有希, 宮崎啓史, 伊藤恒敏, 大和田祐二
- Journal Title
  
  Proceedings Clinical Electron Microscopy
  
  Volume: 35 Pages: 13-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08146
[Journal Article] Gamma/delta intraepithelial lymphocytes in the mouse small intestine.2016
- Author(s)
  Ogata M, Itoh T.
- Journal Title
  
  Anatomical Science International
  
  Volume: 91 Issue: 4 Pages: 301-312
- DOI
  10.1007/s12565-016-0341-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08146
[Journal Article] Shortening of complementarity determining region 3 of the T cell receptor α chain during thymocyte development.2011
- Author(s)
  Matsutani T, Ogata M, Fujii Y, Kitaura K, Nishimoto N,Suzuki R, Itoh T.
- Journal Title
  
  Molecular Immunology.
  
  Volume: 48(4) Pages: 623-629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] マウス小腸絨毛におけるiIELの分布および形態学的性状2011
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Journal Title
  
  リンパ学
  
  Volume: 34(1) Pages: 49-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] マウス小腸絨毛におけるiIELの分布および形態学的性状2011
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Journal Title
  
  リンパ学 34(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Shortening of complementarity determining region 3 of the T cell receptor α chain during thymocyte development.2011
- Author(s)
  Matsutani T, Ogata M, Fujii Y, Kitaura K, Nishimoto N,Suzuki R, Itoh T.
- Journal Title
  
  Molecular Immunology. 48(4)
  
  Pages: 623-629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Comprehensive analysis and characterization of the TCR alpha chain sequences in the common marmoset.2010
- Author(s)
  Fujii Y, Matsutani T, Kitaura K, Suzuki S, Itoh T, Takasaki T, Suzuki R, Kurane I.
- Journal Title
  
  Immunogenetics. 6
  
  Pages: 383-395
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Comprehensive analysis and characterization of the TCR alpha chain sequences in the common marmoset.2010
- Author(s)
  Fujii Y, Matsutani T, Kitaura K, Suzuki S, Itoh T, Takasaki T, Suzuki R, Kurane I.
- Journal Title
  
  Immunogenetics.
  
  Volume: (6) Pages: 383-395
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] DNA repair after DNA fragmentation in mouse small intestinal epithelial cells.2009
- Author(s)
  Ogata M, Oomori T, Soga H, Ota Y, Itoh A, Matsutani T, Nanno M, Suzuki R, Itoh T.
- Journal Title
  
  Cell and Tissue Research. 335
  
  Pages: 371-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] 培養細胞株の微細形態学的検索2009
- Author(s)
  会津清英、伊藤恒敏
- Journal Title
  
  医学と生物学 153
  
  Pages: 488-492
- NAID
  40016891676
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] DNA repair after DNA fragmentation in mouse small intestinal epithelial cells.2009
- Author(s)
  Ogata M, Oomori T, Soga H, Ota Y, Itoh A, Matsutani T, Nanno M, Suzuki R, Itoh T.
- Journal Title
  
  Cell and Tissue Research.
  
  Volume: 335 Pages: 371-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] The interaction of monocytes with rheumatoid synovial cells is a key step in LIGHT-mediated inflammatory bone destruction.2009
- Author(s)
  shida S, Yamane S, Nakano S, Yanagimoto T, Hanamoto Y, Maeda-Tanimura M, Toyosaki-Maeda T, Ishizaki J, Matsuo Y, Fukui N, Itoh T, Ochi T, Suzuki R.
- Journal Title
  
  Immunology.
  
  Volume: 125
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] iIELによる小腸絨毛上皮細胞のDNA断片化後のDNA修復2009
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Journal Title
  
  リンパ学
  
  Volume: 32 Pages: 71-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] 培養細胞株の微細形態学的検索2009
- Author(s)
  会津清英、伊藤恒敏
- Journal Title
  
  医学と生物学
  
  Volume: 153 Pages: 488-492
- NAID
  40016891676
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] BALB/cマウスにおけるT細胞レセプターレパトア解析組織・性別・週齢およびヒドロコルチゾン投与による影響2009
- Author(s)
  北浦一孝、金山喜一、藤井克樹、塩原教之、田中こなぎ、倉根一郎、鈴木さつき、伊藤恒敏、鈴木隆二
- Journal Title
  
  Experimental Animals
  
  Volume: 58 Pages: 159-168
- NAID
  10024838349
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] T cell receptor repertoire in BALB/c mice varies according to tissue type, sex, age, and hydrocortisone treatment.2009
- Author(s)
  Kitaura K, Kanayama K, Fujii Y, Shiobara N, Tanaka K, Kurane I, Suzuki S, Itoh T, Suzuki R.
- Journal Title
  
  Experimental Animals.
  
  Volume: 58 Pages: 159-168
- NAID
  10024838349
- Data Source
  KAKENHI-PROJECT-21590207
[Journal Article] iIELによる小腸絨毛上皮細胞のDNA断片化後のDNA修復2009
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Journal Title
  
  リンパ学 32
  
  Pages: 71-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] T cell receptor repertoire in BALB/c mice varies according to tissue type, sex, age, and hydrocortisone treatment.2009
- Author(s)
  Kitaura K, Kanayama K, Fujii Y, Shiobara N, Tanaka K, Kurane I, Suzuki S, Itoh T, Suzuki R.
- Journal Title
  
  Experimental Animals. 58
  
  Pages: 159-168
- NAID
  10024838349
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] BALB/c マウスにおけるT 細胞レセプターレパトア解析組織・性別・週齢およびヒドロコルチゾン投与による影響2009
- Author(s)
  北浦一孝、金山喜一、藤井克樹、塩原教之、田中こなぎ、倉根一郎、鈴木さつき、伊藤恒敏、鈴木隆二
- Journal Title
  
  Experimental Animals. 58
  
  Pages: 159-168
- NAID
  10024838349
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] The interaction of monocytes with rheumatoid synovial cells is a key step in LIGHT-mediated inflammatory bone destruction.2009
- Author(s)
  Ishida S, Yamane S, Nakano S, Yanagimoto T, Hanamoto Y, Maeda-Tanimura M, Toyosaki-Maeda T, Ishizaki J, Matsuo Y, Fukui N, Itoh T, Ochi T, Suzuki R.
- Journal Title
  
  Immunology. 128
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] iIELによる絨毛上皮細胞のDNA断片化誘発機構と上皮細胞におけるDNA修復機構2008
- Author(s)
  尾形雅君、松谷隆治、伊藤亜里、伊藤恒敏
- Journal Title
  
  リンパ学 31
  
  Pages: 6-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Discovery of novel non-peptide thrombopoietin mimetic compounds that induce megakaryocytopoiesis.2008
- Author(s)
  Yamane N, Takahashi K, Tanaka Y, Kato K, Takayama M, Ohyabu N, Shiota T, Takenaka H, Yoshida Y, Hara S, Murashi T, Nakamura E, Nishitani Y, Ishizaki J, Yamane S, Nagata K, Koizumi K, Yutsudo T, Suzuki R, Itoh T, Takemoto H.
- Journal Title
  
  Bioscience Reports. 28
  
  Pages: 275-285
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients.2008
- Author(s)
  Yamane S, Ishida S, Hanamoto Y, Kumagai K, Masuda R, Tanaka K, Shiobara N, Yamane N, Mori T, Juji T, Fukui N, Itoh T, Ochi T, Suzuki R.
- Journal Title
  
  Journal of Inflammation (Lond). 5
  
  Pages: 5-5
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] LIGHT induces cell proliferation and inflammatory responses of rheumatoid arthritis synovial fibroblasts via lymphotoxin beta receptor.2008
- Author(s)
  Ishida S, Yamane S, Ochi T, Nakano S, Mori T, Juji T, Fukui N, Itoh T, Suzuki R.
- Journal Title
  
  The Journal of Rheumatology. 35
  
  Pages: 960-968
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Characterization of novel non-peptide thrombopoietin mimetics, their species specificity and the activation mechanism of the thrombopoietin receptor.2008
- Author(s)
  Yamane N, Tanaka Y, Ohyabu N, Yamane S, Maekawa K, Ishizaki J, Suzuki R, Itoh T, Takemoto H.
- Journal Title
  
  European Journal of Pharmacology. 586
  
  Pages: 44-51
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Absence of Ku70 gene obliterates X-ray-induced lacZ mutagenesis of small deletions in mouse tissues.2008
- Author(s)
  Uehara Y, Ikehata H, Komura J, Ito A, Ogata M, Itoh T, Hirayama R, Furusawa Y, Ando K, Paunesku T, Woloschak GE, Komatsu K, Matsuura S, Ikura T, Kamiya K, Ono T.
- Journal Title
  
  Radiation Research. 170
  
  Pages: 216-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Inhibition of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 reduces the severity of collagen-induced arthritis.2008
- Author(s)
  Tanaka K, Horikawa T, Suzuki S, Kitaura K, Watanabe J, Gotoh A, Shiobara N, Itoh T, Yamane S, Suzuki R, Fukui N, Ochi T.
- Journal Title
  
  The Journal of Rheumatology. 35
  
  Pages: 2316-2324
- Data Source
  KAKENHI-PROJECT-20590181
[Journal Article] Comparison of CDR3 length among thymocyte subpopulations- impacts of MHC and BV segment on the CDR3 shortening2007
- Author(s)
  Matsutani T, Ohmori T, Ogata M, Soga H, Kasahara S, Yoshioka T, Suzuki R, Itoh T.
- Journal Title
  
  Molecular Immunology 44(9)
  
  Pages: 2378-2387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Journal Article] DNA fragmentation of mouse small intestineal epithelial cells and their DNA repair2007
- Author(s)
  Ogata M, Matsutani T, Itoh A, Itoh T.
- Journal Title
  
  Japanese Journal of Lymphology 31(In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Journal Article] 胸腺は個々のTリンパ球の抗原特異性の決定にどこまで関与しているのか2006
- Author(s)
  伊藤恒敏
- Journal Title
  
  Japanese journal of lymphology 29
  
  Pages: 41-42
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590178
[Journal Article] Alteration of T-cell receptor repertoires during thymic T-cell development2006
- Author(s)
  Matsutani T, Ohmori T, Ogata M, Soga H, Yoshioka T, Suzuki R, Itoh T.,
- Journal Title
  
  Scandinavian journal of immunology 64(1)
  
  Pages: 53-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Journal Article] Does the thymus dictate the specificity of each T cells2006
- Author(s)
  Itoh T.
- Journal Title
  
  Japanese Journal of Lymphology 29
  
  Pages: 41-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Journal Article] Limited VH gene usage in B-cell clones established with nurse-like cells from patients with rheumatoid arthritis2006
- Author(s)
  Nakamura-Kikuoka S, Takahi K, Tsuboi H, Toyosaki-Maeda T, Maeda-Tanimura M, Wakasa C, Kikuchi N, Norioka S, Iwasaki M, Matsutani T, Itoh T, Yamane S, Takemoto H, Tsuruta Y, Shimaoka Y, Yukioka M, Suzuki R, Ochi T.
- Journal Title
  
  Rheumatology (Oxford) 45(5)
  
  Pages: 549-557
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Journal Article] Alterations of T cell receptor repertoire and CDR3 length by thymic selection2006
- Author(s)
  Matsutani T, Ohmori T, Ogata M, Soga H, Itoh T.
- Journal Title
  
  Japanese Journal of Lymphology 29
  
  Pages: 32-35
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Journal Article] Accumulation of intestinal intraepithelial lymphocytes in association with lack of polymeric immunoglobulin receptor.2005
- Author(s)
  Yamazaki, K., Shimada, S., Kato-Nagoka, N., Soga, H., Itoh, T., Nanno, M.
- Journal Title
  
  Eur.J.Immunol. (In press)
- Data Source
  KAKENHI-PROJECT-15659042
[Journal Article] Accumulation of intestinal intraepithelial lymphocytes in association with lack of polymeric immunoglobulin receptor.2005
- Author(s)
  Yamazaki, K., Shimada, S., Kato-Nagoka, N., Soga, H., Itoh, T., Nanno, M.
- Journal Title
  
  Eur.J.Immunol. (In press)
- Data Source
  KAKENHI-PROJECT-16590132
[Journal Article] Accumulation of intestinal intraepithelial lymphocytes in association with lack of polymeric immunoglobulin receptor.2005
- Author(s)
  Yamazaki, K., Shimada, S., Kato-Nagoka, N., Soga, H., Itoh, T., Nanno, M.
- Journal Title
  
  Eur.J.Immunol. (In press)
- Data Source
  KAKENHI-PROJECT-16390045
[Journal Article] Evidence for existence of oligoclonal tumor-infiltrating lymphocytes and predominant production of T helper1/cytotoxic 1 type cytokines in gastric and colorectal tumors.2004
- Author(s)
  Matsutani, T., Shiiba, K., Yoshioka, T., Tsuruta, Y., Suzuki, R., Ochi, T., Itoh, T., Musha, H., Mizoi, T., Sasaki, I.
- Journal Title
  
  Int.J.Oncol. 25
  
  Pages: 133-141
- Data Source
  KAKENHI-PROJECT-16590132
[Journal Article] DNA fragmentation and detachment of enterocytes induced by anti-CD3 mAb-activated intraepithelial lymphocytes.2004
- Author(s)
  Yaguchi, K., Kayaba, S., Soga, H., Yamagishi, M., Tamura, A., Kasahara, S., Itoh, T.
- Journal Title
  
  Cells Tissue Res. 315
  
  Pages: 71-84
- Data Source
  KAKENHI-PROJECT-16390045
[Journal Article] DNA fragmentation and detachment of enterocytes induced by anti-CD3 mAb-activated intraepithelial lymphocytes.2004
- Author(s)
  Yaguchi, K., Kayaba, S., Soga, H., Yamagishi, M., Tamura, A., Kasahara, S., Itoh, T.
- Journal Title
  
  Cell Tissue Res. 315
  
  Pages: 71-84
- Data Source
  KAKENHI-PROJECT-15659042
[Journal Article] Evidence for existence of oligoclonal tumor-infiltrating lymphocytes and predominant production of T helper1/cytotoxic 1 type cytokines in gastric and colorectal tumors.2004
- Author(s)
  Matsutani, T., Shiiba, K., Yoshioka, T., Tsuruta, Y., Suzuki, R., Ochi, T., Itoh, T., Musha, H., Mizoi, T., Sasaki, I.
- Journal Title
  
  Int.J.Oncol. 25
  
  Pages: 133-141
- Data Source
  KAKENHI-PROJECT-15659042
[Journal Article] DNA fragmentation and detachment of enterocytes induced by anti-CD3 mAb-activated intraepithelial lymphocytes.2004
- Author(s)
  Yaguchi, K., Kayaba, S., Soga, H., Yamagishi, M., Tamura, A., Kasahara, S., Itoh, T.
- Journal Title
  
  Cell Tissue Res. 315
  
  Pages: 71-84
- Data Source
  KAKENHI-PROJECT-16590132
[Journal Article] Evidence for existence of oligoclonal tumor-infiltrating lymphocytes and predominant production of T helper1/cytotoxic 1 type cytokines in gastric and colorectal tumors.2004
- Author(s)
  Matsutani, T., Shiiba, K., Yoshioka, T., Tsuruta, Y., Suzuki, R., Ochi, T., Itoh, T., Musha, H., Mizoi, T., Sasaki, I.
- Journal Title
  
  Int.J.Oncol. 25
  
  Pages: 133-141
- Data Source
  KAKENHI-PROJECT-16390045
[Presentation] Ndufs4欠損マウスにおける顎下腺・副腎の形態異常とステロイド合成障害2018
- Author(s)
  小林祐太、尾形雅君、南都文香、香川慶輝、山本由似、宮崎啓史、伊藤将人、香取幸夫, 阿部高明、大和田祐二
- Organizer
  第123回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-15K08146
[Presentation] 腸上皮細胞間リンパ球の活性化に伴う小腸絨毛上皮細胞の剥離機構2018
- Author(s)
  尾形雅君、上条桂樹、伊藤恒敏、大和田祐二
- Organizer
  第123回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-15K08146
[Presentation] 腸上皮細胞間リンパ球(IEL)の抗体刺激に伴う絨毛上皮細胞の剥離機構2017
- Author(s)
  尾形雅君、香川慶輝、安本有希、伊藤恒敏、大和田祐二
- Organizer
  第122回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-15K08146
[Presentation] 腸上皮細胞間リンパ球(IEL)の抗体刺激に伴う絨毛上皮細胞の剥離機構2017
- Author(s)
  尾形雅君, 香川慶輝, 安本有希, 伊藤恒敏, 大和田祐二
- Organizer
  第122回日本解剖学会総会
- Place of Presentation
  長崎大学（長崎県長崎市）
- Year and Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-15K08146
[Presentation] 腸上皮間リンパ球(IEL)における自己作用型DNA傷害およびDNA修復2016
- Author(s)
  尾形雅君, 香川慶輝, 安本有希, 伊藤恒敏, 大和田祐二
- Organizer
  第62回日本解剖学会東北・北海道連合支部学術集会
- Place of Presentation
  帯広畜産大学（北海道帯広市）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-15K08146
[Presentation] 腸上皮細胞間リンパ球(IEL)による新たなDNA断片化誘導機構2012
- Author(s)
  尾形雅君, 伊藤恒敏
- Organizer
  第117回日本解剖学会総会・全国学術総会
- Place of Presentation
  甲府
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21590207
[Presentation] マウス腸上皮細胞間リンパ球(IEL)の活性化および細胞死2011
- Author(s)
  尾形雅君, 大田祐太, 伊藤恒敏
- Organizer
  第35回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21590207
[Presentation] マウスの小腸絨毛におけるiIELの分布および形態学的性状2010
- Author(s)
  尾形雅君, 大田祐太, 松谷隆治, 伊藤恒敏
- Organizer
  第34回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21590207
[Presentation] マウスの小腸絨毛におけるiIELの分布および形態学的性状2010
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Organizer
  第34回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-20590181
[Presentation] マウス小腸絨毛における腸上皮細胞間リンパ球の解析2010
- Author(s)
  大田祐太, 尾形雅君, 松谷隆治, 伊藤恒敏
- Organizer
  第115回日本解剖学会総会
- Place of Presentation
  盛岡
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590207
[Presentation] マウス小腸絨毛における腸上皮細胞間リンパ球の解析2010
- Author(s)
  大田祐太、尾形雅君、松谷隆治、伊藤恒敏
- Organizer
  第115回日本解剖学会総会
- Place of Presentation
  盛岡
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20590181
[Presentation] iIELによる小腸絨毛上皮細胞のDNA断片化後のDNA修復2009
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Organizer
  第33回日本リンパ学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20590181
[Presentation] コモンマーモセットT細胞受容体α鎖およびβ鎖配列の網羅的解析2009
- Author(s)
  Fujii Y, Kitaura K, Matsutani T, Takasaki Too, Ogata M, Suzuki S, Itoh T, Kurane I, Suzuki R
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21590207
[Presentation] マウス小腸における絨毛上皮細胞のDNA修復機構2009
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Organizer
  第114回日本解剖学会総会・全国学術集会
- Place of Presentation
  岡山
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-20590181
[Presentation] iIELによる小腸絨毛上皮細胞のDNA断片化後のDNA修復2009
- Author(s)
  尾形雅君, 大田祐太, 松谷隆治, 伊藤恒敏
- Organizer
  第33回日本リンパ学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21590207
[Presentation] コモンマーモセットT細胞受容体α鎖およびβ鎖配列の網羅的解析2009
- Author(s)
  Fujii Y, Kitaura K, Matsutani T, Takasaki Too, Ogata M, Suzuki S, Itoh T, Kurane I, Suzuki R.
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20590181
[Presentation] iIEL活性化によるマウス小腸絨毛上皮細胞のDNA断片化誘発機構2008
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Organizer
  第32回日本リンパ学会総会
- Place of Presentation
  東京
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20590181
[Presentation] DNA fragmentation and DNA repair of small intestinal epithelial cells2008
- Author(s)
  Ogata M, Matsutani T, Itoh A, Itoh T
- Organizer
  The 113th Annual Meeting of the Japanese Association of Anatomists
- Place of Presentation
  Oita
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Presentation] 腸上皮細胞間リンパ球(iIEL)による小腸絨毛上皮細胞のDNA断片化誘発機構2008
- Author(s)
  尾形雅君、大田祐太、松谷隆治、伊藤恒敏
- Organizer
  日本解剖学会第54回東北・北海道連合支部学術集会
- Place of Presentation
  郡山
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-20590181
[Presentation] DNA repair of mouse small intestinal epithelial cells after DNA fragmentation2007
- Author(s)
  Ogata M, Matsutani T, Itoh A, Itoh T
- Organizer
  The 112nd Annual Meeting of the Japanese Association of Amatomists
- Place of Presentation
  Osaka
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Presentation] γ-H2AX expression in thymocytes undergoing V(D)J recombination2007
- Author(s)
  Itoh A, Matsutani T, Ogata M, Itoh T
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Shinagawa
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Presentation] DNA fragmentation of mouse small intestinal epithelial cells by iIEL and DNA repair in the epithelial cells2007
- Author(s)
  Ogata M, Matsutani T, Itoh A, Itoh T
- Organizer
  The 31st Annual Meeting of the Japanese Society of Lymphology
- Place of Presentation
  Sendai
- Year and Date
  2007-06-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Presentation] 胸腺内Tリンパ球前駆細胞のV(D)J recombinationに伴って発現するγ-H2AXの解析2007
- Author(s)
  伊藤亜里
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  品川
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Presentation] 生体内V(D)J再結合中の胸腺リンパ球におけるγ-H2AXの検出2007
- Author(s)
  伊藤亜里
- Organizer
  第31回日本リンパ学会総会
- Place of Presentation
  仙台
- Year and Date
  2007-06-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Presentation] DNA repair of small intestinal epithelial cells after DNA fragmentation2007
- Author(s)
  Ogata M, Itoh T
- Organizer
  The 18th satellite symposium on the lymphatic and immune system
- Place of Presentation
  Osaka
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178
[Presentation] Detection of γ-H2AX in thymocytes undergoing V(D)J recombination in vivo2007
- Author(s)
  Itoh A, Matsutani T, Ogata M, Itoh T
- Organizer
  The 31st Annual Meeting of the Japanese Society of Lymphology
- Place of Presentation
  Sendai
- Year and Date
  2007-06-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590178

1. OGATA Masaki (50311907)

# of Collaborated Projects: 6 results

# of Collaborated Products: 40 results
2. MATSUTANI Takaji (70372290)

# of Collaborated Projects: 5 results

# of Collaborated Products: 28 results
3. NAKAMURA Masanori (50180394)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. SOGA Hiroyuki (20282121)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
5. YAGI Hideki (40250740)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. YAMAGISHI Mai (90332501)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. SHINEHA Ryuzaburo (20192106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TERASAWA Takayuki (10292319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAYAMA Junzo (60292322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIYAZAKI Syukichi (50282075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAMURA Shinri (20124604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KONDO Shintaro (60186848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. EGAWA Kaoru (60119162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHTSU Susumu (90312553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOKUBUN Shoichi (60186658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OONUMA Masahiro (90344663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SUZUKI Ryuji (70373470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 笠原森 (70161007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 知久一雄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 南野昌信

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Itoh Tsunetoshi 伊藤 恒敏

ITOH Tsunetoshi 伊藤 恒敏

Research Projects

Research Products

Co-Researchers

Analysis of the autocrine DNA fragmentation mechanisms in mouse intestinal intraepithelial lymphocytesPrincipal Investigator

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Distribution of Intraepithelial lymphocytes in the murine small intestine : The variability of the morphological property and functionPrincipal Investigator

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DNA fragmentation of mouse small intestinal epithelial cells by iIEL and DNA repair in the epithelial cells

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Explore the cause of CDR3 shortening during thymocyte selection

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Factors determining T lineage commitment in haematopoietic stem cell.Principal Investigator

Principal Investigator

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DNA fragmentation factor of small intestinal enterocyte induced by activation of intraepithelial lymphocyte

Principal Investigator

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アポトーシス誘導後の断片化DNAの修復Principal Investigator

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Analysis of gene expression in FACS-sorted thymocytesPrincipal Investigator

Principal Investigator

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The proton release mechanism in synovial fibroblasts of rheumatoid arthritis

Principal Investigator

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Analysis of the mechanism of bone destruction by neutrophils

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Mechanisms of pyknotic cell death in vivo and their biological significancePrincipal Investigator

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Development of new composition of peritoneal savage fluids

Principal Investigator

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Research Institution

Microenvironment for thymocyte differentiation, selection and clonal eliminationPrincipal Investigator

Principal Investigator

Project Period (FY)

Itoh Tsunetoshi 伊藤恒敏

ITOH Tsunetoshi 伊藤恒敏